Cov lus sib xyaw thiab tus nqi ntawm cov tshuaj "Liraglutid" hauv cov lus qhia rau kev siv, cov tshuaj zoo, tshuaj xyuas

Cov tshuaj "Liraglutide" tau kis hauv Tebchaws Asmeskas hauv qab lub npe "Victoza." Nws tau siv txij li xyoo 2009 rau kev kho mob ntshav qab zib nrog hom 2 pathology. Qhov no yog qhov tshuaj pleev ntshav hypoglycemic, txhaj nrog nws. Tebchaws Asmeskas, Russia thiab ob peb lwm lub tebchaws tau txais kev tso cai siv. Cov tshuaj yuav muaj ntau lub npe sib txawv nyob ntawm seb lub teb chaws ntawm kev tsim khoom. "Liraglutide" kuj tseem siv tau rau kev kho kev rog rau cov neeg laus.

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tshuaj tov. Nws yog qhia rau subcutaneous tswj hwm. Cov khoom siv tseem ceeb yog liraglutide. Kuj suav nrog ntxiv rau hauv cov khoom muaj pes tsawg leeg:

propylene glycol
hydrochloric acid
phenol
dej
sodium hydrogen phosphate.

Cov nkauj no yog tsim nyog tshaj plaws rau kev ua yeeb yam tshaj tawm los ntawm cov tuam ntxhab. Cov tshuaj nquag ua haujlwm yog qhov sib pev ntawm glucan-zoo li tib neeg peptide. Cov roj ntsha ua kom muaj zog hauv kev tsim cov tshuaj insulin hauv beta hlwb. Yog li, adipose thiab cov leeg nqaij pib nqus cov piam thaj sai dua, muab faib rau hauv cov hlwb, txo nws cov ntsiab lus hauv cov hlab ntshav. Nws hloov tawm tias cov tshuaj yog hypoglycemic. Nws ua tau zoo heev, raws li qhov kev piav qhia nws yog tus cwj pwm los ntawm kev ua kom ntev. Thaum muab tshuaj ib hnub ib zaug, nws khaws cov nyhuv thaum nruab hnub.

Daim ntawv tso tawm

Cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj thiab hauv cov kev daws teeb meem. Tom qab nkag mus rau hauv lub cev, nws tam sim ntawd kho qhov tsim tawm ntawm cov tshuaj insulin. Cov enzymes yog tshuaj ib txwm muaj. Cov koob tshuaj ua haujlwm sai dua piv rau cov ntsiav tshuaj. Hauv qhov hais no, cov kws kho mob tau sau ntawv txhaj tshuaj rau kev siv los ua cov tshuaj tiv thaiv kev rog. "Liraglutide" rau kev txhaj tshuaj muaj nyob rau hauv cov xaum xaum tshwj xeeb nrog rab koob. 1 ml ntawm cov tshuaj muaj 6 mg ntawm cov nquag siv.

Hauv thawv ntawv thawv nrog cov lus qhia tuaj txog 1, 2 lossis 3 syringes. Ib qho kev daws teeb meem ntawm ib qho yog txaus rau 10, 15 lossis 30 hno. Lawv tau tsim nyob hauv qab daim tawv nqaij - hauv xub pwg, plab lossis ncej puab. Nws yog txwv tsis pub txwv tsis pub coj mus ua cov leeg lossis cov leeg ntshav.

Yog tias koj tsis ua txhaum lub ceev ntawm lub pob, ces lub txee lub neej yog 30 hli. Tus cwj mem tau khaws cia ib hlis tom qab txhaj tshuaj thawj, cov tshuaj qhib yuav tsum muab tso rau hauv tub yees ntawm 2 - 8 degrees. Nws yog txwv tsis pub khov, txwv tsis pub cov tshuaj yuav poob qhov hauj lwm zoo.

Pharmacodynamics thiab pharmacokinetics

Cov tshuaj yog cov tshuaj tiv thaiv kab mob zoo, nws pab rau qhov hnyav li qub. Kev pham muaj ntau dhau los ntawm cov neeg mob ntshav qab zib nrog hom 2 qhov txhab.

Tom qab tau nkag mus rau hauv tus neeg mob cov ntshav, cov tshuaj ntau zaus ntau dua qhov kev xav ntawm peptides, uas tso cai rau koj kom lub cev ua haujlwm ntawm cov txiav ua haujlwm thiab ua haujlwm ntawm cov tshuaj insulin. Nws hloov tawm tias cov piam thaj hauv ntshav yuav pib poob qis rau kev coj ua. Ntxiv mus, tag nrho cov txiaj ntsig zoo uas nkag mus rau hauv lub cev nrog zaub mov tau nqus kom raug. Nws hloov tawm tias tus neeg lub cev qhov hnyav yog qhov ib txwm ua, qab los noj mov yog txo qis.

Kev noj cov tshuaj yog raug tso cai nruj me ntsis raws li kws kho mob pom zoo. Koj yuav tsum tsis txhob pib koj tus kheej daim ntawv thov txhawm rau tiv thaiv kev rog. Nws dhau los ua qhov kev xaiv zoo tshaj plaws rau cov neeg mob ntshav qab zib, uas ua rau qhov hnyav nce ntxiv.

"Liraglutide" tej zaum yuav raug muab tshuaj txhawm rau txhawm rau kom muaj qib tsis xwm yeem ntawm glycemia. Qhov kev nqus ntawm cov tshuaj nquag thaum txhaj tshuaj subcutaneous qeeb, thiab lub sijhawm ncav mus rau qhov siab tshaj plaws txog 12 teev tom qab kev tswj hwm.

Kev taw qhia thiab contraindications

Rau cov yuag yuag "Liraglutid" raug tso cai nkaus rau kev pom zoo ntawm cov kws tshaj lij. Nws feem ntau tau qhia rau cov neeg mob ntshav qab zib hom 2, qhia tias cov nyhuv tsis ua tiav tom qab ib txwm muaj noj haus thiab kev ua neej. Cov tshuaj pab ua rau rov ua haujlwm glycemic index thaum nws ua txhaum.

Contraindications rau siv muaj:

ntshav qab zib hom 1
lub cev sib xyaw rau cov Cheebtsam,
pathologies loj ntawm daim siab lossis ob lub raum,
lub siab tsis ua haujlwm 3, 4 qib,
o nyob rau hauv cov hnyuv
mob qog hauv cov qog ua ntshav,
lactation, cev xeeb tub.

Nws tsis raug cais tawm, tab sis feem ntau nws tsis pom zoo siv rau hauv cov xwm txheej zoo li no:

tib lub sijhawm xws li txhaj tshuaj insulin,
neeg dhau 75 xyoo
cov neeg mob pancreatitis.

Nrog kev ceev faj, tus kws kho mob sau ntawv rau "Liraglutid" rau cov kab mob plawv. Cov nyhuv thiab tshuaj tiv thaiv ntawm cov yeeb yaj kiab thaum tswjhwm nrog lwm txoj hauv kev rau qhov poob phaus tseem tsis tau tsim. Tsis tas yuav tsum ua kev sim, sim ntau cov qauv rau poob phaus. Cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo yuav tsum tsis txhob siv cov tshuaj, hauv kev nkag, tsuas yog tus kws kho mob tau sau tseg tom qab kuaj pom tus mob tas.

Sab sij huam

Tom qab paub koj tus kheej nrog cov lus qhia rau cov tshuaj, nws pom tseeb tias ua ntej koj pib kho nrog cov tshuaj, koj yuav tsum xyuas seb nws puas yuav ua mob rau lub xeev kev noj qab haus huv ntau dua.

Feem ntau cov kev phiv tshuaj rau cov ntsiav tshuaj lossis kev daws yog qhov mob plab zom zaub mov. Hauv 50% ntawm cov kev mob tshwm sim, xeev siab heev, ntuav rov qab tshwm sim.

Txhua tus neeg mob ntshav qab zib thib tsib nrog kev kho mob"Liraglutidom" yws cov teeb meem hauv kev ua haujlwm ntawm lub plab - feem ntau nws yog mob raws plab tsis txaus los yog cem quav tas li.

Cov kev mob tshwm sim suav nrog kev mob hnyav, mob sai sai.

Qee zaum thaum noj cov tshuaj ntau kawg, cov piam thaj hauv cov hlab ntshav poob qis zuj zus. Hauv qhov xwm txheej no, ib rab diav ntawm zib ntab yuav pab sai sai rau tus neeg mob lub siab.

Tsuas tshuaj thiab tshaj

Qhov hno tsuas yog muab tau rau lwm tus hauv lub plab, xub pwg lossis ncej puab. Nws raug nquahu kom hloov qhov chaw txhaj tshuaj kom tsis txhob ua rau lipodystrophy. Ib qho ntxiv, txoj cai ntawm kev txhaj tshuaj yog cov lus qhia hauv tib lub sijhawm ntawm ib hnub. Tsuas tshuaj yog xaiv ib qho zuj zus los ntawm tus kws tshaj lij.

Kev kho mob feem ntau pib nrog 0.6 mg ib hnub ib zaug. Raws li qhov tsim nyog, qhov koob tshuaj tau nce ntxiv txog 1.2 mg thiab txawm txog 1.8 mg. Qhov koob txhaj tshuaj yuav tsum tsis txhob nce siab dhau 1.8 mg. Ib qho ntxiv, tus kws kho mob tuaj yeem sau tshuaj Metformin lossis cov tshuaj raws li cov tshuaj ua kom nquag los ntawm tib lub npe. Txhawm rau tiv thaiv cov ntshav qog ntshav qab zib, tus kws kho mob yuav tsum tau saib xyuas kev kho mob, tuaj yeem kho nws nyob ntawm qhov kev hloov pauv. Hloov pauv dab tsi rau koj tus kheej yog txwv tsis pub.

Yog qee qhov cai rau kev npaj thiab siv cwj mem-koob txhaj tshuaj:

nco ntsoov them rau lub txee lub neej,
txoj kev daws teeb meem yuav tsum ua kom pob tshab, tsis muaj ntxoov ntxoo, huab tshuaj noj txwv tsis pub siv,
cov koob uas siv tas yuav tsum nruj nreem txuas rau ntawm cov koob txhaj tshuaj,
sab nraud txoj phuam qhwv txoj phuam yog qhov ceev tseg, sab hauv yog pov tseg,
ib rab koob tshiab xav tau lub koob tshiab tiv thaiv kev tiv thaiv lossis txhaws,
yog tias rab koob yog khoov lawm, puas ntsoog, nws yog txwv tsis pub siv nws.

Nrog rau kev siv dhau lawm, cov duab hauv qab no soj ntsuam:

xeev siab, tsis muaj zog thiab ntuav
tsis qab los noj mov
nplawm
zawv plab

Kev mob hypoglycemia tsis txhim kho, muab tau tias tib lub sijhawm tus neeg mob tsis siv tshuaj rau qhov poob phaus.

Raws li cov lus qhia, nyob rau hauv cov ntaub ntawv ntawm kev noj ntau dhau, ntxias ua kom ntuav txhawm rau txhawm rau tso lub plab los ntawm cov tshuaj ntawm cov tshuaj thiab nws cov metabolites. Rau qhov no, sorbents uas xav tau, tom qab ntawd cov tsos mob kev kho mob tau pom tseeb. Qhov tshwm sim ntawm kev tshaj koob tshuaj tsuas yog zam tau yog tias cov qauv xaiv raug ua raws li nruj me ntsis. Nws tsim los ntawm tus kws kho mob, nws kuj tswj cov txheej txheem thiab cov txiaj ntsig.

Kev sib txuam

Hauv cov txheej txheem ntawm kev tshawb nrhiav tshuaj, "Liraglutide" pom tias tsis muaj peev xwm ntawm kev sib txuam tshuaj.

Thaum siv cov tshuaj no, kev tso quav me ntsis tuaj yeem tshwm sim, uas cuam tshuam rau cov txheej txheem nqus ntawm cov tshuaj noj ntawm qhov ncauj. Tab sis xws li cov nyhuv tsis tsim nyog yuav tsum tau txiav txim siab tseem ceeb. Ib qho kev kis mob ntawm zawv plab zom zaws tsis tshua pom muaj nrog kev siv tib neeg lub qhov ncauj.

Cov tshuaj muaj ntau yam analogues thiab generics.

Lub npe ntawm cov tshuaj	Nqi	Txoj kev thov, tso tawm daim ntawv, cov yam ntxwv	Kev muab tshuaj txhua hnub
"Orsoten"	los ntawm 600 rubles	Nqa nrog zaub mov lossis tom qab ib teev. Muaj nyob hauv tsiav tshuaj	120 mg
Forsiga	los ntawm 2400 rub.	Nws yog tso tawm tsuas yog qhia los ntawm tus kws kho mob, nws ua rau qeeb dua qhov nqus ntawm cov piam thaj, txo qhov kev nqus ntawm cov tshuaj tom qab noj mov	nruab nrab 10 mg
Reduxin	los ntawm 1600 rub.	Nws muaj ntau yam contraindications, muaj nyob ntawm cov tshuaj, koj tuaj yeem siv sijhawm ntev kawg ntawm 2 xyoos	10 mg
Novonorm	los ntawm 160 rub.	Muaj cov ntawv yuav tshuaj, cov tus nqi pheej yig	16 mg
"Kev kuaj mob"	los ntawm 200 rub.	Txais tsuas yog ua ntej noj mov, tuaj yeem faib tau yam tsis muaj daim ntawv yuav tshuaj, tus nqi pheej yig	cov koob tshuaj thawj ntawm 0.5 mg, tom qab ntawd 4 mg

Tsuas yog kws kho mob tuaj yeem txiav txim siab qhov kev xav tau los hloov nrog analogues, qhov tsim nyog ntawm lawv siv rau qhov poob phaus. Nws yog qhov tsis tsim nyog los coj tus kheej-tshuaj, vim nws tuaj yeem ua rau muaj kev phom sij txaus ntshai thiab tsis muaj peev xwm nyob rau hauv cov txiaj ntsig ntawm cov nyiaj.

Tom qab ib hlis ntawm kev siv cov tshuaj, qab zib pib ua kom ruaj khov, txawm hais tias nws nyuaj heev rau kev ntsuas tsis tau ua ntej. Ib qho ntxiv, Kuv tau ua raws li tag nrho cov kev cai uas tus kws kho mob tau tsim - ib qho khoom noj. Nws tseem yuav tsum tau muab sau tseg tias tau muaj kev mob siab rau mob caj pas.

Valentina, 45 xyoo

Kuv noj "Liraglutide" rau 3 lub hlis, tsis muaj kev phiv tshuaj tshwm sim. Thawj ob peb hnub, xeev siab me ntsis thiab mob taub hau me ntsis tshwm sim tuaj. Ntxiv nrog rau qhov kev tshwm sim hypoglycemic, Kuv poob ceeb thawj, qab los noj mov tsis tau zoo heev.

Cov tshuaj "Liraglutid" tau tag nrho cov teeb meem ntawm cov ntshav qab zib kom ntau. Qhov tseem ceeb tshaj plaws yog los tshawb xyuas lub txee lub neej thiab qhov tseeb ntawm cov tshuaj ua ntej yuav. Koj yuav tsum tau yuav khoom raws li kws kho mob muab ntawv tshwj xeeb hauv khw muag tshuaj.

Tus nqi yog nyob ntawm qhov ntau npaum ntawm cov tshuaj nquag:

daws rau kev txhaj tshuaj 6 mg hauv 1 ml - los ntawm 10 txhiab rubles.,
cwj mem kua-18 mg rau ib 3 ml ntawm kev daws - los ntawm 9 txhiab rubles.

Xaus

Cov kws kho mob hais tias rau txhua tus neeg mob nws yuav tsum xaiv ib qho zuj zus los xaiv lub koob tshuaj "Liraglutid". Qhov no yuav pab kom tshem tawm qhov teeb meem yuag tshaj plaws, sai sai ua rau cov piam thaj ntau ntau. Vim li no, kev siv tshuaj kho mob raug tso cai tsuas yog tom qab sab laj tswv yim tshwj xeeb.