Insulin Humalog: yuav ua li cas thov, ntau npaum li cas yog qhov siv tau thiab nqi

Humalog® QuickPentTM txhaj 100 IU / ml, 3 ml

1 ml ntawm kev daws

cov tshuaj heev - insulin lispro 100 IU (3.5 mg),

zam txim: metacresol, glycerin, zinc oxide (hais txog Zn ++), sodium hydrogen phosphate, hydrochloric acid 10% txhawm rau kho cov pH, sodium hydroxide 10% tov los kho cov pH, dej rau kev txhaj tshuaj.

Cov kua ntshiab tsis muaj kua

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Cov chaw muag tshuaj ntawm lyspro insulin yog pom los ntawm kev nqus sai thiab ncov cov ntshav tom qab 30 - 70 feeb tom qab txhaj tshuaj subcutaneous.

Lub sijhawm ua haujlwm ntawm cov insulin lispro tuaj yeem sib txawv hauv cov neeg mob sib txawv lossis txawv sijhawm hauv tus neeg mob tib yam thiab nyob ntawm koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, kub cev thiab kev tawm dag zog.

Thaum cov tshuaj insulin raug txhaj, lyspro qhia tau tias kev nqus sai dua li piv nrog kev lom neeg tib neeg cov kua dej hauv cov neeg mob raum thiab mob hepatic tsis txaus, ntxiv rau kev tshem tawm sai dua rau cov neeg mob uas tsis muaj kabmob hepatic. Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus nrog ntau lub raum ua rau lub raum ua haujlwm, qhov txawv ntawm cov tshuaj lyspro insulin thiab insulin luv luv feem ntau ua rau thiab tsis nyob ntawm kev mob raum.

Glucodynamic lo lus teb rau lyspro insulin tsis yog nyob ntawm kev ua haujlwm tsis ua haujlwm ntawm lub siab thiab lub raum.

Lyspro insulin tau pom tias yog ua kom sib luag rau tib neeg cov tshuaj insulin, tab sis nws cov kev ua tshwm sim sai dua thiab kav rau lub sijhawm luv.

Cov Tshuaj Hauv Tshuaj

Lyspro insulin yog ib qho DNA sib txuas ntawm tib neeg cov tshuaj insulin. Nws txawv ntawm tib neeg cov insulin hauv kev rov qab hloov zuj zus ntawm cov amino acids ntawm txoj haujlwm 28 thiab 29 ntawm cov kab hluav taws xob insulin B.

Kev ua tseem ceeb ntawm insulin lyspro yog kev cai ntawm cov metabolism hauv cov piam thaj. Ntxiv rau, nws muaj anabolic thiab anti-catabolic cuam tshuam rau ntau cov ntaub so ntswg lub cev. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab kev nce ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Cov chaw muag tshuaj profile ntawm insulin lyspro hauv cov menyuam yaus zoo ib yam li ntawd rau cov laus.

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj ntawm Humalog® yog txiav txim los ntawm tus kws kho mob tshwj xeeb, nyob ntawm qhov xav tau ntawm tus neeg mob.

Humalog® tuaj yeem muab rau noj ua ntej noj mov, yog tias tsim nyog tam sim tom qab noj mov. Humalog® yuav tsum tau muab tshuaj raws li kev txhaj tshuaj subcutaneous. Yog tias tsim nyog (piv txwv, tswj cov theem ntawm cov piam thaj hauv cov ntshav thaum lub caij ketoacidosis, mob hnyav, tom qab lub sijhawm txiav lossis tom qab lub sijhawm ua haujlwm) Humalog® tuaj yeem muab tshuaj.

Txhaj tshuaj subcutaneous yuav tsum tau muab rau lub xub pwg, lub duav, lub pob tw lossis lub plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom qhov chaw qub tsis siv ntau tshaj li ib hlis ib zaug.

Nrog rau kev tswj hwm ntawm subcutaneous ntawm Humalog®, kev saib xyuas yuav tsum ua kom tsis txhob nkag rau cov hlab ntshav thaum txhaj tshuaj. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Cov neeg mob yuav tsum tau kawm txog cov txheej txheem kev txhaj tshuaj kom raug.

Humalog® yog tus cwj pwm los ntawm kev pib sai dua thiab lub sijhawm ua haujlwm luv (2-5 teev) nrog kev tswj hwm subcutaneous piv rau cov neeg ua haujlwm insulin. Kev pib sai ntawm kev nqis tes ua tso cai rau koj los tswj cov tshuaj tam sim ntawd ua ntej noj mov. Lub sijhawm ua li cas ntawm ib qho insulin tuaj yeem sib txawv hauv cov neeg sib txawv thiab ntau lub sijhawm ntawm tib tug neeg. Lub sijhawm pib sai dua ntawm kev ua ntawm cov tshuaj, piv nrog soluble tib neeg cov tshuaj insulin, nws tswj tau tsis hais qhov chaw ntawm qhov chaw txhaj tshuaj. Lub sijhawm ua haujlwm ntawm Humalog® nyob ntawm lub koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, qhov kub thiab lub cev ua si ntawm tus neeg mob.

Ntawm kev pom zoo ntawm tus kws kho mob tau mus kawm, Humalog® nyob rau hauv hom kev txhaj tshuaj subcutaneous tuaj yeem kho nrog kev ua kom ntev nrog insulins lossis sulfonylurea derivatives.

Npaj rau kev qhia

Kev daws ntawm cov tshuaj yuav tsum yog cov ntshiab thiab tsis muaj kob. Ib qho huab, tuab lossis xim me ntsis ntawm cov tshuaj, lossis yog tias cov khoom tawg tau pom los rau hauv nws, yuav tsum tsis txhob siv.

Kev Siv Cov Ntsuas Ua Ntej Ua Kom Siv Cov Cwj Mem

Ua ntej muab cov tshuaj insulin, koj yuav tsum ua tib zoo nyeem QuickPen-Syringe cwj mem cov lus qhia rau Siv. Hauv cov txheej txheem ntawm kev siv QuickPenTM koob txhaj tshuaj, nws yog qhov tsim nyog yuav tsum ua raws li cov lus pom zoo tau muab hauv Phau Ntawv Qhia.

Xaiv qhov chaw txhaj tshuaj.

Npaj cov tawv nqaij ntawm qhov chaw txhaj tshuaj raws li kws kho mob pom zoo.

Tshem lub hau tiv thaiv sab nraud ntawm rab koob.

Kho cov tawv nqaij los ntawm kev khaws nws hauv qhov ntau quav.

Ntxig lub koob txhaj tshuaj subcutaneously mus rau hauv cov quav ntim thiab ua kev txhaj tshuaj raws li cov lus qhia siv kev siv tus xaum xim.

Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj nrog paj rwb pas nrig rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.

Siv lub hau sab tiv thaiv ntawm rab koob, unscrew lub koob tawm thiab pov tseg.

Tso lub hau rau ntawm tus cwj mem xaum qhuav.

Nws yog ib qho tsim nyog yuav tsum tau hloov chaw txhaj tshuaj kom qhov chaw qub tsis siv ntau tshaj ib hlis ib zaug.

Cov phwj uas siv cov khoom muag, cov khoom tsis siv, koob tshuaj, thiab cov khoom siv yuav tsum tau muab pov tseg kom ua raws li hauv zos.

QuickPen ™ Daim duab qhia txog cwj mem

Thaum siv QUICKPEN AND SYRINGE HANDLES, THOV nyeem cov ntaub ntawv tseem ceeb no ua ntej.

Taw qhia

QuickPen ™ syringe cwj mem tau yooj yim siv. Nws yog cov cuab yeej siv los tswj cov tshuaj insulin (ib qho “insulin cwj mem”) muaj 3 ml (300 units) ntawm kev npaj tshuaj insulin nrog ib qho dej ntawm 100 IU / ml. Koj tuaj yeem hno ntawm 1 txog 60 units ntawm insulin rau ib zaug txhaj. Koj tuaj yeem tsim koj koob tshuaj ib zaug zuj zus. Yog tias koj tau teeb tsa ntau cov koog, koj tuaj yeem kho qhov koob tshuaj uas tsis muaj qhov poob ntawm insulin.

Ua ntej siv QuickPen ™ Syringe cwj mem, nyeem phau ntawv qhia tag nrho thiab ua raws li nws cov lus qhia kom meej. Yog tias koj tsis ua raws li tag nrho cov lus qhia no, koj yuav tau txais cov tshuaj insulin tsawg dhau los yog siab dhau.

Koj daim QuickPen ™ insulin cwj mem yuav tsum siv rau kev txhaj tshuaj nkaus xwb. Tsis txhob kis tus cwj mem los yog rab koob rau lwm tus, vim qhov no yuav ua rau kis tus kab mob. Siv ib rab koob tshiab rau txhua txoj kev txhaj tshuaj.

TSIS TXHOB SIV cov xaum xaum hluav taws xob yog ib qho ntawm nws qhov chaw raug puas tsuaj lossis tawg.

Yuav tsum tau xaum ib qho xaum xoob xoob uas siv thaum siv xaum xaum los yog nws puas ntsoog.

Nws tsis raug nquahu kom siv cov kua xaum xaum rau cov neeg mob uas tsis pom kev lossis tsis pom kev zoo yam tsis muaj kev pab cuam ntawm cov neeg tsis muaj teeb meem tsis pom kev, kev kawm los ua haujlwm nrog cov xaum xaum hluav taws xob.

Cwj mem ceev ceev Kev npaj™

Nyeem thiab ua raws cov lus qhia rau kev siv teev tseg hauv cov lus qhia no rau kev siv tshuaj.

Kuaj daim ntawv lo rau ntawm lub phwj qhwv ua ntej txhua yam kev txhaj tshuaj kom paub tseeb tias hnub tas sij hawm ntawm cov tshuaj tsis tau tas sij hawm thiab koj siv hom insulin tseeb, tsis txhob tshem daim ntawv lo los ntawm tus cwj mem syringe.

Nco tseg: Cov xim ntawm QuickPick ™ syringe cwj mem koob khawm sib raug rau cov xim ntawm pob txaij ntawm daim duab lo tus xaum xaj thiab nyob ntawm hom insulin. Hauv phau ntawv no, khawm koob tshuaj yog grayed tawm. Cov xim xiav ntawm QuickPen ring syringe cwj mem lub cev qhia tau tias nws yog npaj rau siv nrog cov khoom lag luam Humalog®.

Xim Coding ntawm Koob Yees Duab:

DNA recombinant tib neeg cov tshuaj insulin. Nws txawv ntawm qhov kawg hauv kev rov ua dua ntawm cov amino acids ntawm txoj haujlwm 28 thiab 29 ntawm cov kab hluav taws xob insulin B.

Lub txiaj ntsig tseem ceeb ntawm cov tshuaj yog kev tswj hwm ntawm cov metabolism hauv qab ntuj. Tsis tas li ntawd, nws muaj qhov ua kom anabolic. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab kev nce ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Hauv cov neeg mob uas muaj hom 1 thiab hom 2 mob ntshav qab zib mellitus, thaum siv cov tshuaj insulin lyspro, hyperglycemia uas tshwm sim tom qab noj mov tau nce ntau dua piv rau kev tiv thaiv tib neeg cov kua dej. Rau cov neeg mob tau txais cov tshuaj insulins luv luv thiab hauv paus, nws yog ib qho tsim nyog yuav tsum xaiv cov koob tshuaj ntawm ob qho insulins thiaj li ua tiav cov ntshav qabzib kom zoo thoob plaws ib hnub.

Ib yam li txhua qhov kev npaj tshuaj insulin, lub sijhawm lyspro insulin ua haujlwm tuaj yeem sib txawv hauv cov neeg mob lossis sijhawm sib txawv ntawm tib tus neeg mob thiab nyob ntawm lub koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, kub cev thiab kev tawm dag zog.

Cov yam ntxwv ntawm lyspro insulin hauv cov menyuam yaus thiab cov hluas yog cov zoo sib xws ntawm cov neeg laus saib.

Hauv cov neeg mob uas muaj ntshav qab zib hom 2 tau txais cov tshuaj sulfonylurea ntau tshaj plaws, qhov ntxiv ntawm lyspro insulin ua rau muaj qhov txo qis hauv glycated hemoglobin.

Lyspro insulin kho nyob rau hauv cov neeg mob uas muaj hom 1 thiab ntshav qab zib hom 2 yog nrog nws cov neeg tsawg zuj zus mus ntawm nocturnal hypoglycemia.

Qhov glucodynamic lo lus teb rau isulin lispro tsis vam khom rau kev ua haujlwm tsis zoo ntawm lub raum lossis nplooj siab.

Lyspro insulin tau pom tias yog ua kom sib luag rau tib neeg cov tshuaj insulin, tab sis nws cov kev ua tshwm sim sai dua thiab kav rau lub sijhawm luv.

Lyspro insulin yog tus cwj pwm los ntawm qhov pib sai ntawm kev coj ua (li 15 feeb), raws li Nws muaj qhov nqus dej siab, thiab qhov no tso cai rau koj nkag mus rau nws tam sim ntawd ua ntej noj mov (0-15 feeb ua ntej noj mov), hauv kev sib piv rau cov pa luv luv ua yeeb yam (30-45 feeb ua ntej noj mov). Lyspro insulin muaj lub sijhawm luv dua (2 mus rau 5 teev) piv rau tib neeg cov tshuaj insulin.

Xuas thiab faib khoom

Tom qab cov tswj hwm sc, Lyspro insulin yog nqus tau sai thiab nce mus txog C_max hauv cov ntshav ntshav tom qab 30-70 feeb. V_d Lyspro insulin thiab insulin cov tib neeg ib txwm muaj zoo ib yam thiab muaj nyob hauv qhov ntau ntawm 0.26-0.36 l / kg.

Nrog sc tswj hwm T_1/2 lyspro insulin yog li 1 teev. Cov neeg mob lub raum thiab hepatic insufficiency tau tuav tus nqi ntawm lyspro insulin nqus ntau dua piv rau tib neeg cov tshuaj insulin.

- mob ntshav qab zib mellitus hauv cov neeg laus thiab menyuam yaus, yuav tsum tau siv cov tshuaj insulin los pab tswj cov ntshav qabzib kom ntau.

Tus kws kho mob txiav txim siab muab koob tshuaj ib leeg zuj zus, nyob ntawm qhov xav tau ntawm tus neeg mob. Cov tshuaj Humalog ® tuaj yeem muab noj ua ntej noj mov, yog tias yuav tsum tau ua sai tom qab noj mov.

Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.

Humalog ® raug tswj s / c nyob rau hauv daim ntawv ntawm kev txhaj tshuaj lossis hauv daim ntawv ntawm kev txuas ntxiv s / c infusion siv lub twj tso kua mis. Yog tias tsim nyog (ketoacidosis, mob hnyav, lub sijhawm ntawm kev ua haujlwm lossis sijhawm hla sijhawm) Humalog ® tuaj yeem nkag mus rau hauv / hauv.

SC yuav tsum muab rau lub xub pwg, ncej puab, pob tw, lossis plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj 1 zaug hauv ib hlis. Thaum s / qhia txog cov tshuaj Humalog ®, yuav tsum saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntsha. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug.

Cov cai ntawm kev tswj hwm ntawm cov tshuaj Humalog ®

Npaj rau kev qhia

Tshuaj yeeb tshuaj Humalog Hum yuav tsum yog pob tshab thiab xim tsis muaj xim. Ib qho huab, tuab lossis xim me ntsis ntawm cov tshuaj, lossis yog tias cov khoom tawg tau pom los rau hauv nws, yuav tsum tsis txhob siv.

Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj (tus cwj mem-txhaj), txuas lub koob thiab coj kev txhaj tshuaj insulin, nws yog qhov yuav tsum tau ua raws li cov khw muag cov lus qhia uas txuas nrog txhua tus xaum xim.

2. Xaiv lub xaib rau kev txhaj tshuaj.

3. Tshuaj tua kab mob los kho cov tawv nqaij ntawm qhov chaw txhaj tshuaj.

4. Tshem tawm lub hau ntawm rab koob.

5. Kho cov tawv nqaij los ntawm kev ncab nws lossis los ntawm kev ruaj ntseg ntawm cov quav loj. Ntxig lub koob txhaj tshuaj raws li cov lus qhia siv kev xaum xim.

6. Nias lub pob ntawd.

7. Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.

8. Kev siv rab koob rab koob, tshem tawm rab koob thiab rhuav tshem nws.

9. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom qhov chaw qub siv tsis ntau tshaj li 1 zaug hauv ib hlis.

Kev tswj hwm ntawm insulin

Kev txhaj tshuaj ntawm cov tshuaj Humalog ® yuav tsum ua raws li kev siv tshuaj txhaj rau txoj kev txhaj tshuaj, piv txwv, txhaj tshuaj bolus tswj lossis siv cov txheej txheem infusion. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav.

Lub tshuab ua ke nrog cov ntsiab lus los ntawm 0.1 IU / ml txog rau 1.0 IU / ml insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose daws yog ruaj khov nyob rau hauv chav tsev rau 48 teev.

P / C insulin infusion siv lub twj tso kua mis

Rau Txoj kev lis ntshav ntawm Humalog ®, Minimed thiab Disetronic twj tuaj yeem siv rau insulin infusion. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Txoj kev lis ntshav yog hloov pauv txhua 48 teev .Thaum txuas lub infusion system, kev cai aseptic tau pom. Thaum muaj qhov qog ntawm hypoglycemic, Txoj kev lis ntshav yog nres kom txog rau thaum rov zoo. Yog tias pheej rov qab lossis qis dua cov piam thaj hauv cov ntshav tau sau tseg, tom qab ntawd nws yog qhov yuav tsum tau qhia rau tus kws kho mob txog qhov no thiab txiav txim siab txo lossis tso tseg qhov insulin infusion. Lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav tuaj yeem ua rau nce ntxiv hauv cov piam thaj. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, npaj Humalog ® yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.

Sab nyhuv cuam tshuam nrog cov nyhuv tseem ceeb ntawm cov tshuaj: ntshav qog. Kev mob ntshav khov ntau heev tuaj yeem ua rau tsis nco qab (hypoglycemic coma) thiab, tshwj tsis yog rau kev tuag.

Kev tsis haum tshuaj: kev ua xua nyob hauv zos muaj peev xwm ua tau - liab, o lossis khaus ntawm qhov chaw txhaj tshuaj (feem ntau yuav ploj mus li ob peb hnub lossis ob peb asthiv), kev tsis haum tshuaj (feem ntau tsis tshua muaj, tab sis muaj mob loj dua) - ua kom khaus, ua pob khaus, mob txha caj qaum, ua npaws, ua tsis taus pa, tsawg HELL, tachycardia, nce hws. Cov uas muaj mob hnyav raug neeg lub cev tuaj yeem tas sim neej.

Cov tshuaj tiv thaiv hauv zos: lipodystrophy ntawm thaj chaw txhaj tshuaj.

- Hypersensitivity rau cov tshuaj.

Txog rau hnub no, tsis muaj qhov xav tau ntawm Lyspro insulin rau kev xeeb tub lossis kev noj qab haus huv ntawm tus menyuam / tus menyuam tshiab tau pom. Tsis muaj cov kev tshawb fawb nthuav txog kab mob sib kis.

Lub hom phiaj ntawm insulin txoj kev kho mob thaum cev xeeb tub yog tswj hwm cov ntshav qabzib kom txaus rau cov neeg mob ntshav qab zib insulin-los yog mob ntshav qab zib hauv lub ntsej muag. Qhov xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb thaum cev xeeb tub.Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.

Cov poj niam muaj hnub nyoog yug menyuamCov neeg mob ntshav qab zib yuav tsum qhia lawv tus kws kho mob txog kev xeeb tub uas tab tom npaj lossis npaj ua ntej. Thaum cev xeeb tub, cov neeg mob ntshav qab zib yuav tsum ua tib zoo saib xyuas cov ntshav qabzib, nrog rau kev saib xyuas neeg mob txhua yam.

Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.

Cov tsos mob hypoglycemia, nrog rau cov tsos mob hauv qab no: qaug zog, tawm hws ntau, mob tachycardia, mob taub hau, ntuav, tsis meej pem.

Kev Kho Mob: ntshav qab zib tsawg feem ntau nres ntawm kev noj cov piam thaj lossis lwm yam piam thaj, lossis los ntawm cov khoom uas muaj suab thaj.

Kev kho cov ntshav qog ntshav me ntsis tuaj yeem nqa nrog kev pab los ntawm a / m lossis s / c tswj hwm ntawm glucagon, tom qab ntawd kev noj zaub mov carbohydrates tom qab kev tswj hwm tus neeg mob lub cev. Cov neeg mob uas tsis teb rau glucagon raug muab iv dextrose (glucose) tov.

Yog tias tus neeg mob tsis nco qab, tom qab ntawd glucagon yuav tsum tau txhaj rau hauv / m lossis s / c. Thaum tsis muaj cov glucagon los sis yog tias tsis muaj tshuaj tiv thaiv rau nws txoj kev tswj hwm, nws yog qhov tsim nyog los qhia qhov kev daws teeb meem ntawm cov tshuaj tov ua kua (glucose). Tam sim ntawd tom qab rov qab nco qab, tus neeg mob yuav tsum tau txais cov zaub mov muaj carbohydrate-nplua nuj.

Ntxiv rau kev txhawb nqa cov carbohydrate kom tsawg thiab kev tshuaj xyuas cov neeg mob tej zaum yuav tsum ua, raws li Ib qho kev rov qab los ntawm hypoglycemia yog ua tau.

Cov nyhuv hypoglycemic txo tau los ntawm qhov ncauj qhov kev tiv thaiv, corticosteroids, thyroid hormone npaj, danazol, beta₂-adrenomimetics (suav nrog rhytodrine, salbutamol, terbutaline), tricyclic antidepressants, thiazide diuretics, chlorprotixen, diazoxide, isoniazid, lithium carbonate, nicotinic acid, phenothiazine derivatives.

Cov nyhuv hypoglycemic ntawm Humalog yog txhim kho los ntawm beta-blockers, ethanol thiab ethanol-muaj cov tshuaj, anabolic steroids, fenfluramine, guanethidine, tetracyclines, tshuaj tiv thaiv hypoglycemic, salicylates (piv txwv li, acetylsalicylic acid, aniloprilactyl antagonists, MAP inhibitors, Ml. angiotensin II cov neeg txais.

Humalog alog yuav tsum tsis txhob tov nrog tsiaj tshuaj insulin.

Humalog ® tuaj yeem siv (nyob rau hauv kev saib xyuas ntawm tus kws kho mob) hauv kev sib xyaw nrog cov insulin ua haujlwm ntev dua los yog siv cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, sulfonylurea derivatives.

Cov tshuaj yog ntawv yuav tshuaj.

Sau npe B. Cov tshuaj yuav tsum muab cia kom ncav tsis cuag ntawm cov menyuam yaus, hauv lub tub yees, ntawm qhov txias li 2 ° txog 8 ° C, tsis txhob cia kom khov. Txee lub neej yog 2 xyoos.

Cov tshuaj yeeb hauv kev siv yuav tsum khaws cia hauv chav sov li ntawm 15 ° txog 25 ° C, tiv thaiv los ntawm tshav ntuj ncaj qha thiab kub. Txee lub neej - tsis pub dhau 28 hnub.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo qis nrog lub siab tsis ua haujlwm.

Hauv cov neeg mob uas muaj daim siab tsis txaus, tus nqi ntau dua ntawm kev nqus ntawm lyspro insulin tseem piv rau cov neeg muaj peev xwm insulin.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo nrog lub raum tsis ua haujlwm.

Hauv cov neeg mob uas lub raum tsis ua haujlwm, ntau dua qhov feem ntau ntawm kev nqus ntawm lyspro insulin yog tswj piv rau cov neeg siv tshuaj insulin.

Hloov chaw ntawm tus neeg mob mus rau lwm hom lossis hom tshuaj insulin yuav tsum tau ua raws li kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tsim tawm), hom (piv txwv, tsis tu ncua, NPH, Daim kab xev), hom (tsiaj, tib neeg, tib neeg insulin analogue) thiab / lossis cov qauv kev tsim tawm (DNA recombinant insulin lossis insulin ntawm keeb kwm tsiaj) yuav xav tau hloov pauv cov koob tshuaj.

Kev mob uas cov cim qhia ntxov ntawm hypoglycemia yog qhov tsis tseem ceeb thiab tsis tshua hais tawm muaj xws li txuas ntxiv cov ntshav qab zib mellitus, kev kho mob insulin ntau ntxiv, kab mob hauv cov kab mob ntshav qab zib mellitus, lossis tshuaj noj, xws li beta-blockers.

Hauv cov neeg mob hypoglycemic tshua tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tswj tsis tau tus mob hypoglycemic lossis hyperglycemic tshua tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag.

Kev noj tshuaj tsis txaus lossis tsis ua haujlwm ntawm kev kho mob, tshwj xeeb tshaj yog cov tshuaj insulin-mob ntshav qab zib mellitus, tuaj yeem ua rau hyperglycemia thiab ntshav qab zib ketoacidosis, cov xwm txheej uas yuav tsim kev phom sij rau lub neej ntawm tus neeg mob.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo cov neeg mob lub raum tsis ua haujlwm, zoo ib yam li cov neeg mob lub siab ua haujlwm vim qhov ua haujlwm tsawg kawg ntawm gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin.

Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce nrog cov kis kab mob, kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov carbohydrates hauv cov zaub mov noj.

Yog hais tias tus neeg mob lub cev qoj ib ce ntau zog los yog pauv noj zaub mov zoo ces kuj tseem yuav tsum tau txhaj koob tshuaj. Kev tawm dag zog tam sim ntawd tom qab noj mov tas yuav ua rau muaj ntshav qab zib tsawg dua. Ib qhov tshwm sim ntawm lub pharmacodynamics ntawm kev ua yeeb yam sai sai ntawm insulin analogues yog tias yog tias cov ntshav qog ntshav qab zib, tom qab ntawd nws tuaj yeem txhim kho tom qab txhaj tshuaj dua li thaum txhaj cov tshuaj tiv thaiv tib neeg cov tshuaj insulin.

Tus neeg mob yuav tsum tau ceeb toom tias yog tias tus kws kho mob tau sau ib qho tshuaj insulin nrog rau 40 IU / ml hauv lub vial, ces cov tshuaj insulin yuav tsum tsis txhob los ntawm daim cartridge nrog cov tshuaj insulin ntawm 100 IU / ml nrog koob txhaj rau kev txhaj tshuaj insulin nrog qhov sib luag ntawm 40 IU / ml.

Yog tias nws yuav tsum tau noj lwm yam tshuaj tib lub sijhawm uas Humalog ®, tus neeg mob yuav tsum sab laj nrog kws kho mob.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Nrog hypoglycemia lossis hyperglycemia cuam tshuam nrog kev noj tshuaj tsis zoo, kev ua txhaum ntawm kev muaj peev xwm mloog zoo thiab qhov ceev ntawm psychomotor cov tshuaj tiv thaiv tuaj yeem tau. Qhov no tuaj yeem dhau los ua kev pheej hmoo rau cov haujlwm muaj kev phom sij (suav nrog kev tsav tsheb lossis kev ua haujlwm nrog cov tshuab).

Cov neeg mob yuav tsum tau ceev faj kom tsis txhob muaj hypolycemia thaum tsav tsheb. Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas muaj qhov txo qis los yog tsis hnov qhov zoo ntawm cov tsos mob ua ntej rau tus mob ntshav qab zib tsawg, los yog leej twg muaj qee yam cov ntshav qog ntshav qis. Hauv cov xwm txheej no, nws yog qhov yuav tsum tau los ntsuas qhov ua tau ntawm kev tsav tsheb. Cov neeg mob ntshav qab zib muaj peev xwm tiv thaiv nws tus kheej los ntawm kev muaj ntshav qabzib tsawg tsawg los ntawm kev noj ntshav qabzib lossis zaub mov ntau hauv carbohydrates (Nws raug nquahu kom koj ib txwm muaj tsawg kawg 20 g piam thaj nrog koj). Tus neeg mob yuav tsum qhia tus kws kho mob uas koom nrog paub txog qhov hloov pauv hypoglycemia.

Insulin Humalog: yuav ua li cas thov, ntau npaum li cas yog qhov siv tau thiab nqi

Video (nyem mus ua si).

Dua li ntawm qhov tseeb hais tias cov kws tshawb fawb tswj tau kom rov ua tiav cov tshuaj insulin molecule, uas tsim tawm hauv tib neeg lub cev, qhov kev ua ntawm cov tshuaj hormones tseem ua rau qeeb qeeb vim lub sijhawm xav kom nqus mus rau hauv cov ntshav. Thawj cov tshuaj ntawm kev ua kom zoo dua yog cov tshuaj insulin Humalog. Nws pib ua haujlwm tau ntev lawm 15 feeb tom qab txhaj tshuaj, yog li ntawd cov suab thaj los ntawm cov ntshav pauv mus rau cov ntaub so ntswg hauv lub sijhawm, thiab txawm tias lub sijhawm luv luv hyperglycemia tsis tshwm sim.

Video (nyem mus ua si).

Piv nrog cov neeg tsim insulins yav dhau los, Humalog qhia tau zoo dua: hauv cov neeg mob, txhua hnub hloov pauv hauv qab zib yog li 22%, glycemic qhov ntsuas tau zoo, tshwj xeeb tshaj yog yav tav su, thiab qhov muaj feem yuav ua rau muaj ntshav siab qeeb tsawg dua. Vim tias qhov nrawm nrawm, tab sis qhov kev txiav txim ruaj khov, qhov insulin no nce hauv kev mob ntshav qab zib.

Cov lus qhia txog kev siv tshuaj insulin Humalog yog qhov hluav taws xob heev, thiab cov ntu piav qhia txog kev phiv thiab cov lus qhia rau kev siv nyob ntau dua ib kab lus. Cov lus piav qhia ntev ntev uas sib xyaw nrog qee cov tshuaj tau pom los ntawm cov neeg mob yog lus ceeb toom txog kev phom sij ntawm kev coj lawv. Qhov tseeb, txhua yam muaj qhov sib txawv: ib qho loj, cov lus qhia ntxaws ntxaws - cov ntaub ntawv pov thawj ntawm ntau yam kev sim siabtias cov tshuaj no thev taus zoo.

Humalogue tau txais kev pom zoo rau kev siv ntau dua 20 xyoo dhau los, thiab tam sim no nws muaj kev ruaj ntseg hais tias cov tshuaj insulin no muaj kev nyab xeeb ntawm kev siv tshuaj. Nws tau txais kev pom zoo rau kev siv los ntawm ob tus neeg laus thiab menyuam yaus; nws tuaj yeem siv rau hauv txhua kis nrog los ntawm kev tsis muaj tshuaj tiv thaiv hnyav: hom 1 thiab hom 2 mob ntshav qab zib, mob ntshav qab zib hauv lub cev, thiab phais mob phais.

Cov ntaub ntawv dav dav txog qhov Humalogue:

Ntshav qab zib Hom 1, tsis hais tus kheej ntawm tus kabmob.
Hom 2, yog tias cov kab mob ntshav qog ntshav qab zib thiab kev noj zaub mov tsis pub ua rau lub cev tsis ua haujlwm glycemia.
Yam 2 thaum siv tes taw, ntshav qab zib hauv lub tes taw.
Ob hom ntshav qab zib thaum kho nrog ketoacidotic thiab hyperosmolar coma.

tshuaj los kho kev mob ntshav siab nrog cov nyhuv diuretic,
kev npaj tshuaj hormones, suav nrog qhov ncauj tawm tsam,
nicotinic acid siv los kho mob ntshav qab zib.

Txhim khu cov nyhuv:

cawv
hypoglycemic cov neeg sawv cev siv los kho hom 2 mob ntshav qab zib,
tshuaj aspirin
ib feem ntawm cov tshuaj tiv thaiv kab mob.

Yog tias cov tshuaj no tsis tuaj yeem hloov los ntawm lwm tus, qhov tshuaj ntawm Humalog yuav tsum tau kho ib ntus.

Ntawm cov kev mob tshwm sim, hypoglycemia thiab kev fab tshuaj tsis haum yog feem ntau pom (1-10% ntawm neeg mob ntshav qab zib). Tsawg dua 1% ntawm cov neeg mob tsim muaj lipodystrophy ntawm thaj chaw txhaj tshuaj. Qhov ntau zaus ntawm lwm cov kev tsis sib haum yog tsawg dua 0.1%.

Hauv tsev, Humalog yog tswj hwm subcutaneously siv rab koob xaum qhuav los yog lub tshuab nqus insulin. Yog tias muaj mob loj heev yuav tsum raug tshem tawm, kev tswj hwm cov tshuaj no kuj tuaj yeem ua rau hauv cov chaw kho mob. Hauv qhov no, nquag tswj cov piam thaj yog qhov tsim nyog kom tsis txhob noj ntau dhau.

Cov tshuaj nquag ua haujlwm ntawm cov tshuaj yog insulin lispro. Nws txawv ntawm tib neeg cov tshuaj hormones hauv kev npaj cov amino acids hauv cov qauv molecule. Xws li kev hloov kho tsis tiv thaiv cov cell receptors los ntawm kev paub txog cov tshuaj hormones, yog li lawv yooj yim dhau suab thaj rau lawv tus kheej Qhov humalogue tsuas muaj cov tshuaj insulin monomers - ib qho, tsis txuas yam tsis txawv. Vim tias qhov no, nws yog nqus tau nrawm thiab tusyees, pib txo cov piam thaj sai dua li cov tshuaj insulin tsis haum.

Qhov tshuaj Humalog yog qhov tshuaj yeeb-luv dua li piv txwv li, Humulin lossis Actrapid. Raws li kev faib tawm, nws tau xa mus rau cov tshuaj insulin sib piv nrog cov kev ua kom haum. Qhov pib ntawm nws cov kev ua tau nrawm dua, li 15 feeb, yog li cov neeg mob ntshav qab zib tsis tas tos kom txog thaum cov tshuaj ua haujlwm, tab sis koj tuaj yeem npaj zaub mov noj tom qab txhaj tshuaj. Ua tsaug rau qhov tsis txaus no, nws yuav yooj yim rau kev npaj zaub mov noj, thiab qhov kev pheej hmoo tsis nco qab cov zaub mov tom qab kev txhaj tshuaj yog txo qis dua.

Rau kev tswj zoo glycemic, kev siv tshuaj tua kab mob sai yuav tsum tau ua ke nrog qhov tsim nyog siv ntawm cov insulin ntev. Tib qho kev zam tsuas yog kev siv lub tshuab nqus dej twj tso kua mis rau ntawm lub sijhawm txuas ntxiv.

Kev noj tshuaj Humalog ntau nyob ntawm ntau yam thiab txiav txim siab ntawm tus kheej rau txhua tus mob ntshav qab zib. Kev siv cov qauv txheem yog tsis pom zoo, vim tias lawv ua rau kev mob ntshav qab zib hnyav dua. Yog tias tus neeg mob ua raws li cov zaub mov uas tsis muaj carbohydrate tsawg, qhov koob tshuaj ntawm Humalog yuav tsawg dua li cov qauv ntawm kev tswj hwm tuaj yeem muab tau. Hauv qhov no, nws pom zoo kom siv cov tshuaj insulin uas tsis muaj zog tuaj.

Ultrashort cov tshuaj hormones muab cov nyhuv loj tshaj. Thaum hloov mus rau Humalog, nws qhov kev pib noj tshuaj yog xam raws li 40% ntawm kev siv insulin luv luv. Raws li cov txiaj ntsig ntawm glycemia, ntau npaum li cas tau kho. Qhov xav tau qhov nruab nrab ntawm kev npaj rau ib khob cij yog 1-1.5 units.

Lub humalogue yog pricked ua ntej txhua pluas noj, tsawg kawg peb zaug hauv ib hnubCov. Nyob rau hauv cov ntaub ntawv ntawm cov piam thaj siab, kho cov menyuam hlob nyob nruab nrab ntawm kev txhaj tshuaj tseem ceeb raug tso cai. Cov kev qhia rau kev siv pom zoo xam lub xav tau cov tshuaj insulin raws li cov khoom noj uas tau npaj rau kev noj mov tom ntej. Txog 15 feeb yuav tsum dhau los ntawm kev txhaj tshuaj mus rau cov zaub mov.

Raws li kev txheeb xyuas, lub sijhawm no feem ntau tsawg dua, tshwj xeeb yog thaum tav su, thaum cov tshuaj tiv thaiv insulin tsawg dua. Qhov nqus tus nqi yog nruj me ntsis rau ib tus neeg, nws tuaj yeem raug suav siv rov ua ntsuas ntsuas cov ntshav qab zib sai sai tom qab txhaj. Yog tias cov ntshav qab zib ua rau pom qhov cuam tshuam sai dua li cov lus qhia, lub sijhawm ua ntej noj mov yuav tsum raug txo kom tsawg.

Humalog yog ib qho tshuaj sai tshaj plaws, yog li nws yooj yim siv nws ua kev pabcuam thaum muaj xwm txheej ceev rau cov ntshav qab zib yog tias tus neeg mob tau hem nrog lub cev kub ntxhov.

Lub ncov ntawm ultrashort insulin yog pom 60 feeb tom qab nws tswj hwm. Lub sijhawm ua haujlwm nyob ntawm lub koob tshuaj; qhov loj dua nws yog, ntev li ntawm cov suab thaj txo qis dua yog nyob hauv nruab nrab - kwv yees li 4 teev.

Neej Neeg tshaj 25

Txhawm rau kom ntsuas qhov tseeb ntawm qhov tshwm sim ntawm Humalog, qabzib yuav tsum tau ntsuas tom qab lub sijhawm no, feem ntau qhov no ua tiav ua ntej noj mov tom ntej. Kev ntsuas ua ntej yog xav tau yog xav tias tsam lub qog ntshav qab zib tsawg.

Lub sijhawm luv luv ntawm lub Humalog tsis yog qhov ua tsis zoo, tab sis qhov zoo ntawm cov tshuaj. Ua tsaug rau nws, cov neeg mob ntshav qab zib mellitus tsis tshua muaj kev tiv thaiv ntshav qab zib, tshwj xeeb tshaj yog thaum tsaus ntuj.

Koj puas mob siab los ntshav siab? Koj puas paub tias kub siab ua rau lub plawv nres thiab ntaus cwj nrag? Ntsig koj lub siab nrog. Lub tswv yim thiab cov lus qhia hais txog tus qauv nyeem ntawm no >>

Ntxiv rau qhov Humalog, lub tuam txhab kev lag luam kws tsim tshuaj Lilly France tsim cov Humalog Mix. Nws yog kev sib xyaw ntawm lyspro insulin thiab protamine sulfate. Ua tsaug rau qhov kev sib txuam no, lub sijhawm pib ntawm cov tshuaj hormone tseem zoo li qub, thiab lub sijhawm ua haujlwm tau nce ntxiv.

Humalog Mix yog muaj nyob rau hauv 2 ntau qhov:

Cov lus qhia rau kev siv luv-ua yeeb yam insulin Humalog (kev daws thiab rho tawm Mix)

Lub teb chaws Fabkis zoo tshuaj insulin Humalog tau ua pov thawj nws zoo tshaj li analogues, uas yog ua tiav vim muaj kev sib txuam zoo ntawm cov kev ua haujlwm tseem ceeb thiab cov khoom pab txhawb nqa. Kev siv cov tshuaj insulin no ua kom yooj yim rau kev sib ntaus los tiv thaiv hyperglycemia hauv cov neeg mob kev mob ntshav qab zib.

Luv insulin Humalog yog tsim los ntawm Fabkis lub tuam txhab Lilly Fabkis, thiab cov qauv qauv ntawm nws tso tawm yog qhov pom tseeb thiab tsis muaj kob, muab ntim rau hauv tshuaj ntsiav lossis lub taub hau. Lub tom kawg tuaj yeem muag tau raws li ib feem ntawm qhov tau npaj Txiag ceev syringe cwj mem, lossis cais rau tsib ampoules rau 3 ml hauv ib lub hlwv. Raws li lwm txoj hauv kev, Humalog Mix npaj ua tau tsim nyob rau hauv daim ntawv ntawm kev ncua rau kev tswj hwm subcutaneous, qhov ib txwm Humalog Mix tuaj yeem muab tshuaj nrog dej.

Lub hauv paus ua haujlwm tseem ceeb ntawm Humalog yog insulin lispro - ob-theem tshuaj ntawm qhov kub siab ntawm 100 IU rau 1 ml ntawm kev daws, qhov kev ua ntawm uas tau tswj hwm los ntawm cov khoom siv hauv qab no ntxiv:

glycerol
metacresol
zinc oxide
sodium hydrogen phosphate heptahydrate,
hydrochloric acid daws,
Cov kua sodium hydroxide.

Los ntawm qhov pom ntawm cov pab pawg soj ntsuam thiab chaw muag tshuaj, Humalog yog hais txog cov yeeb yam ntawm cov neeg ua haujlwm insulin, tab sis txawv ntawm lawv hauv cov kab rov qab ntawm cov amino acids.Lub luag haujlwm tseem ceeb ntawm cov tshuaj yog tswj hwm kev nqus ntawm cov piam thaj, txawm hais tias nws tseem muaj cov yam ntxwv ntawm anabolic. Pharmacologically, nws ua raws li hauv qab no: hauv cov leeg nqaij, nce qib ntawm glycogen, fatty acids thiab glycerol yog kho, nrog rau kev nce ntxiv hauv cov concentration ntawm cov protein thiab kev noj cov amino acids los ntawm lub cev. Nyob rau hauv tib yam, cov txheej txheem xws li glycogenolysis, gluconeogenesis, lipolysis, protein catabolism, thiab ketogenesis qeeb.

Cov kev tshawb fawb pom tau tias hauv cov neeg mob uas muaj ob hom mob ntshav qab zib mellitus tom qab noj mov, cov ntshav qab zib nce tsawg dua sai dua yog tias Humalog siv es tsis txhob siv lwm cov tshuaj insulin.

Nws yog ib qho tseem ceeb kom nco ntsoov tias yog tias tus mob ntshav qab zib ib txhij tau txais cov tshuaj insulin luv luv thiab basal insulin, nws yuav tsim nyog kho qhov ntau npaum ntawm ob qho tshuaj thawj thiab thib ob kom tau txais txiaj ntsig zoo tshaj plaws. Dua li ntawm qhov tseeb tias Humalog yog cov insulins luv luv ua haujlwm, lub sijhawm kawg ntawm nws cov kev txiav txim siab raug txiav txim los ntawm ntau yam rau txhua tus neeg mob:

tsuas tshuaj
chaw txhaj tshuaj
lub cev kub
kev siv lub cev
zoo ntawm cov ntshav txaus.

Nyias, nws yog tsim nyog sau cia qhov tseeb tias Humalog insulin zoo sib xws rau tib neeg cov ntshav qab zib thiab kho cov menyuam yaus lossis cov hluas. Nws tseem tsis hloov pauv tias cov nyhuv ntawm cov tshuaj tsis yog nyob ntawm qhov yuav tshwm sim ntawm lub raum lossis lub siab ua haujlwm hauv tus neeg mob, thiab thaum ua ke nrog cov koob tshuaj sulfonylurea ntau, cov qib ntawm glycated hemoglobin ho txo qis. Feem ntau, tau muaj tus cim txo qis hauv cov neeg mob nocturnal hypoglycemia, los ntawm cov neeg mob ntshav qab zib feem ntau raug kev txom nyem yog tias lawv tsis noj cov tshuaj uas tsim nyog.

Cov yam ntxwv ntawm Humalog insulin qhia hauv cov lej zoo li qhov no: qhov pib ntawm kev nqis tes yog 15 feeb tom qab txhaj, lub sijhawm ua haujlwm yog los ntawm ob txog tsib teev. Ntawm ib sab tes, lub sijhawm ua haujlwm zoo ntawm cov tshuaj qis dua li ntawm cov tshuaj sib piv, thiab ntawm lwm qhov, nws tuaj yeem siv 15 feeb ua ntej noj mov, thiab tsis yog 30-35, zoo li lwm qhov insulins.

Insulin Humalog yog npaj rau txhua tus neeg mob uas mob hyperglycemia thiab xav tau kev kho mob insulin. Nws tuaj yeem yog ib lo lus nug ntawm ob hom 1 mob ntshav qab zib mellitus, uas yog cov kab mob tiv thaiv insulin, thiab hom ntshav qab zib hom 2, uas cov ntshav qab zib cov ntshav nce ntxiv tom qab ib pluas noj muaj carbohydrates.

Cov tshuaj insulin luv luv yuav ua tau zoo nyob rau txhua ntu ntawm tus kabmob, zoo rau cov neeg mob ntawm pojniam thiab pojniam txhua lub hnub nyoog. Raws li kev kho kom zoo, nws txoj kev sib xyaw ua ke nrog nruab nrab thiab ntev ua haujlwm insulins, pom zoo los ntawm tus kws kho mob tuaj koom, suav tias yog.

Muaj tsuas yog ob pawg kev sib txuam rau kev siv ntawm Humalog: tus neeg tsis kam mus rau ib qho lossis lwm qhov tshuaj ntawm cov tshuaj thiab mob qog ntshav qab zib, uas qhov tshuaj tiv thaiv hypoglycemic yuav tsuas txhim kho cov kev ua tsis zoo hauv lub cev. Txawm li cas los xij, ib tug xov tooj ntawm cov nta thiab taw qhia yuav tsum raug txiav txim siab thaum siv cov tshuaj insulin no:

cov kev tshawb fawb tsis qhia pom qhov tsis zoo ntawm Humalog rau kev xeeb tub thiab kev noj qab haus huv ntawm tus menyuam hauv plab (thiab cov menyuam tshiab),
insulin txoj kev kho yog qhia rau cov poj niam cev xeeb tub uas mob insulin-mob ntshav qab zib los yog mob ntshav qab zib hauv lub cev, thiab hauv cov ntsiab lus no, nws yuav tsum nco ntsoov tias qhov xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis, thiab tom qab ntawd nce los ntawm kev txiav tawm zaum ob thiab thib peb. Tom qab yug menyuam, qhov kev xav tau no yuav txo qis dua, uas yuav tsum tau coj mus rau hauv tus account,
thaum npaj kev cev xeeb tub, tus poj niam muaj ntshav qab zib yuav tsum sab laj nrog nws tus kws kho mob, thiab yav tom ntej, yuav tsum ua tib zoo saib xyuas nws tus mob,
tej zaum qhov yuav tsum tau kho qhov tshuaj ntawm lub Humalog thaum pub niam mis, nrog rau kev kho cov zaub mov noj,
cov mob ntshav qab zib nrog lub raum lossis hepatic insufficiency muaj qhov nqus tau sai ntawm Humalog piv rau lwm cov tshuaj insulin,
ib qho kev hloov pauv hauv kev kho tshuaj insulin xav tau kev soj ntsuam los ntawm kws kho mob: hloov mus rau lwm hom tshuaj insulin, hloov hom tshuaj, hloov qoj ib ce.

Cov kws kho mob tau qhia txog qhov tseeb txog tus mob ntshav qab zib! Mob ntshav qab zib yuav ploj mus nyob rau hauv 10 hnub yog tias koj haus nws sawv ntxov. »Nyeem ntxiv >>>

Nws yuav tsum nco ntsoov tias kev kho mob insulin ntau dua tuaj yeem ua rau tsis muaj qhov tsis txaus lossis tsis tshua muaj kev hais tawm tias yuav mob ntshav qab zib tsawg (qhov no tseem siv rau tus neeg mob hloov ntawm tsiaj insulin mus rau Humalog). Nws tseem ceeb heev uas yuav tsum xav txog qhov tseeb tias ob qho tib si kev noj tshuaj ntau dhau thiab kev tso cia qhov siv tsis tas ntawm nws txoj kev siv tuaj yeem ua rau hyperglycemia. Tus mob ntshav qab zib xav tau cov insulin nyhav ntxiv nrog rau ntxiv ntshav qab zib rau cov kab mob sib kis lossis kev ntxhov siab.

Raws li kev mob tshwm sim, cov tshuaj nquag ntawm cov tshuaj tuaj yeem ua rau cov ntshav qog ntshav qab zib, thaum lub sijhawm sib koom ua ke ntawm lwm tus neeg pabcuam hauv qee kis ua rau:

kev tawm tsam hauv zos (liab lossis khaus ntawm qhov chaw txhaj tshuaj),
kev tsis haum rau lub cev (ua kom khaus, ua kom khaus, mob ua npaws, kub cev, edema, tachycardia, txo cov ntshav siab, tawm hws ntau dhau),
lipodystrophy ntawm thaj chaw txhaj tshuaj.

Thaum kawg, noj tshuaj ntau dhau ntawm Humalog ua rau muaj ntshav qab zib ntau heev nrog txhua qhov tshwm sim: tsis muaj zog, tawm hws ntau ntxiv, lub plawv tsis sib luag, mob taub hau thiab ntuav. Kev mob hypoglycemic yog tso tseg los ntawm kev ntsuas tus qauv: kev noj cov piam thaj lossis lwm yam khoom muaj suab thaj.

Kev siv ntawm Humalog pib nrog kev suav qhov suav tshuaj, uas tau txiav txim siab los ntawm tus kws kho mob tau kawm, nyob ntawm tus mob ntshav qab zib xav tau cov tshuaj insulin. Cov tshuaj no tuaj yeem muab rau ob leeg ua ntej thiab tom qab noj mov, txawm hais tias thawj txoj kev xaiv zoo dua. Nco ntsoov nco ntsoov tias kev daws teeb meem yuav tsum tsis txhob txias, tab sis sib piv nrog chav sov. Feem ntau, ib qho qauv koob txhaj tshuaj, cwj mem, lossis insulin twj tso kua mis yog siv los tswj nws, txhaj tshuaj subcutaneously, txawm li cas los xij, nyob rau qee qhov xwm txheej, kev tso ntshav nkag tseem raug tso cai.

Kev txhaj tshuaj subcutaneous tau nqis tes yog ntawm tus ncej puab, lub xub pwg, lub plab lossis lub pob tw, qhov chaw hloov mus rau lwm qhov thiaj li siv tib qho tsis ntau tshaj ib hlis ib zaug. Kev saib xyuas yuav tsum tau ua kom tsis txhob nkag mus rau txoj leeg ntshav, thiab nws kuj tseem yuav tsum nruj me ntsis kom tsis txhob zaws tawv nqaij hauv qhov chaw txhaj tshuaj tom qab nws tau ua. Lub humalog muas hauv daim ntawv ntawm tus cartridge rau daim ntawv xaum yog siv hauv qhov kev txiav txim hauv qab no:

koj yuav tsum ntxuav koj ob txhais tes nrog dej sov thiab xaiv qhov chaw rau kev txhaj tshuaj,
cov tawv nqaij hauv thaj chaw txhaj tshuaj yog tshuaj tua kab mob nrog cov tshuaj tua kab mob,
qhov kev tiv thaiv tau muab tshem tawm los ntawm rab koob,
daim tawv nqaij yog tsau manually los ntawm rub los yog rub tawm kom cov quav tau,
ib rab koob tau ntxig rau hauv daim tawv nqaij, lub pob nyem rau ntawm rab koob xaum yog nias,
lub koob raug tshem tawm, qhov chaw txhaj tshuaj yog maj mam nias rau ob peb feeb (tsis tas yuav zaws thiab txhuam),
nrog kev pab ntawm lub hau tiv thaiv, lub koob tau muab tso tseg thiab tshem tawm.

Tag nrho cov kev cai no siv rau cov hom tshuaj no zoo li Humalog Mix 25 thiab Humalog Mix 50, tsim nyob rau hauv daim ntawv ntawm ncua kev kawm. Qhov sib txawv nyob rau hauv qhov pom thiab npaj rau ntau hom tshuaj: kev daws teeb meem yuav tsum tsis muaj xim thiab pob tshab, thaum nws tam sim ntawd npaj rau kev siv, thaum lub sijhawm muab ncua yuav tsum tau co ob peb zaug kom lub cartridge muaj qhov tsis sib xws, kua huab, zoo ib yam li mis.

Kev siv tshuaj tiv thaiv ntawm Humalog yog nqa tawm hauv qhov chaw kho mob uas siv tus txheej txheem infusion uas qhov kev daws teeb meem yog tov nrog 0.9% sodium chloride tov lossis 5% dextrose daws. Kev siv cov tshuaj insulin twj rau kev qhia ntawm Humalog yog txhim tsa raws li cov lus qhia uas txuas rau ntawm lub cuab yeej. Thaum nqa tawm kev txhaj tshuaj ntawm ib yam twg, koj yuav tsum nco ntsoov cov piam thaj 1 ntau ntawm cov insulin txo cov piam thaj kom thiaj li ntsuas tau qhov koob tshuaj thiab tshuaj tiv thaiv ntawm lub cev. Qhov nruab nrab, qhov ntsuas no yog 2.0 mmol / L rau kev npaj tshuaj insulin feem ntau, uas kuj muaj tseeb rau Humalog.

Qhov sib cuam tshuam yeeb tshuaj ntawm Humalog nrog lwm cov tshuaj nyob rau hauv sib haum rau nws cov analogues. Yog li, qhov ua kom lub ntsej muag hypoglycemic yuav txo qis thaum nws tau ua ke nrog kev tiv thaiv qhov ncauj, glucocorticosteroids, cov tshuaj hormones rau cov thyroid caj pas, tus lej ntawm diuretics thiab tshuaj tiv thaiv kab mob, nrog rau nicotinic acid.

Tib lub sijhawm, cov nyhuv ntshav hypoglycemic ntawm insulin yuav ua rau muaj zog nrog kev siv tshuaj los ntawm kev siv:

beta blockers,
ethanol thiab tshuaj raws li nws,
anabolic tshuaj yuam
cov tshuaj hypoglycemic qhov ncauj,
sulfonamides.

Cov xov tooj ntawm tes yuav tsum muab tso rau hauv qhov chaw uas cov me nyuam nkag tsis tau rau hauv lub tub yees zoo, ntawm qhov kub ntawm +2 txog +8 degrees Celsius. Cov txheej txheem txee lub neej yog ob xyoos. Yog tias cov pob twb tau qhib lawm, cov tshuaj insulin no yuav tsum ceev cia hauv chav sov li ntawm +15 txog +25 degrees Celsius.

Kev saib xyuas yuav tsum tau ua kom ntseeg tau tias cov tshuaj tsis ua kom sov thiab tsis nyob rau hauv tshav ntuj. Thaum pib siv, lub txee lub neej txo mus rau 28 hnub.

Cov tshuaj tiv thaiv ncaj qha ntawm Humalog yuav tsum xav txog tag nrho cov tshuaj insulin npaj rau cov ntshav qab zib hauv txoj kev zoo sib xws. Ntawm cov nto moo tshaj plaws yog Actrapid, Vosulin, Gensulin, Insugen, Insular, Humodar, Isofan, Protafan thiab Homolong.

Rau cov neeg mob uas muaj mob ntshav qab zib hom 1, txhaj tshuaj insulin yog qhov yuav tsum tau ua nyob rau txhua hnub uas yuav pab tswj cov suab thaj kom huv.

Niaj hnub no, muaj ntau yam kev hloov ntawm cov tshuaj no.

Cov neeg mob teb tau zoo rau cov tshuaj Humalogmix, uas muaj ntawv sib txawv. Kuj, tsab xov xwm piav qhia cov lus qhia rau nws siv.

Humalog yog tshuaj uas yog ib qho tshuaj noj ntawm lub cev insulin tsim los ntawm tib neeg lub cev. DNA yog hloov kho tus neeg sawv cev. Qhov peculiarity yog tias Humalog hloov cov lus sib xyaw ntawm cov amino acid hauv cov kab txuas insulin. Cov tshuaj tswj cov metabolism hauv cov piam thaj hauv lub cev. Nws yog hais txog cov tshuaj uas muaj cov teebmeem anabolic.

Kev txhaj tshuaj ntawm cov tshuaj pab txhawm rau txhawm rau ntxiv glycerol, fatty acids thiab glocogen hauv lub cev. Pab ua kom muaj protein ntau sib txuas. Cov txheej txheem kev noj cov amino acids yog nrawm, uas ua rau kom txo qis ketogenesis, glucogenogenesis, lipolysis, glycogenolysis, protein catabolism. Cov tshuaj no muaj cov nyhuv luv luv.

Lub ntsiab lus ntawm Humalog yog insulin lispro. Kuj, qhov muaj pes tsawg leeg yog ntxiv nrog kev ua si ntawm kev ua hauv cheeb tsam. Tseem muaj qhov sib txawv ntawm cov tshuaj - Humalogmix 25, 50 thiab 100. Nws lub ntsiab sib txawv yog muaj Hagedorn nyob rau hauv nruab nrab provitamin, uas ua rau qeeb qeeb ntawm cov tshuaj insulin.

Tus xov tooj 25, 50 thiab 100 qhia tus naj npawb ntawm NPH hauv tshuaj. Ntau Humalogmix muaj qhov ua kom nruab nrab tsis txaus ntseeg Hagedorn, ntau dua cov tshuaj noj yuav ua. Yog li, koj tuaj yeem txo qhov xav tau ntau los ntawm kev txhaj tshuaj, tsim rau ib hnub. Kev siv cov tshuaj no pab tswj kev kho mob kom qab zib thiab ua lub neej yooj yim.

Zoo li txhua yam tshuaj Humalogmix 25, 50 thiab 100 muaj qhov tsis zoo.

Cov tshuaj tsis tso cai rau kev tswj hwm kom ua tiav cov ntshav qab zib.

Tseem muaj kev paub txog kev ua xua ntawm kev phiv tshuaj thiab lwm cov kev mob tshwm sim. Cov kws kho mob feem ntau sau ntawv tshuaj insulin Humalog nyob rau hauv daim ntawv ntshiab tsis yog kev sib tov, vim tias ntau npaum li cas ntawm NPH 25, 50 thiab 100 tuaj yeem ua rau cov ntshav qab zib tsis txaus, feem ntau lawv dhau los ua mob ntev. Nws yog qhov siv tau los siv ntau hom thiab ntau txoj kev kho mob rau cov neeg laus laus uas nyob nrog ntshav qab zib.

Feem ntau, cov kev xaiv ntawm cov tshuaj no yog vim muaj lub sijhawm luv luv ntawm cov neeg mob thiab kev loj hlob ntawm cov senile dementia. Rau cov seem ntawm cov neeg mob, Humalog hauv nws daim ntawv dawb huv yog kev pom zoo.

Yuav ua li cas kom qab zib kom zoo nyob rau hauv 2019

Cov ntawv sau los ntawm peb cov nyeem

Kuv tus niam pog tau mob ntshav qab zib tau ntev ntev (hom 2), tab sis tsis ntev los no cov teeb meem tau ploj mus ntawm nws ob txhais ceg thiab hauv nruab nrog cev.

Kuv txhob txwm nrhiav tau ib tsab xov xwm hauv Is Taws Nem uas khaws kuv lub neej. Nws yog qhov nyuaj rau kuv pom qhov tsim txom, thiab qhov tsis hnov tsw phem hauv chav tsev tau ua rau kuv vwm.

Los ntawm cov chav kawm ntawm kev kho, lub granny txawm hloov nws lub siab. Nws tau hais tias nws ob txhais ceg tsis raug mob thiab qhov mob tsis huam vam li lawm; lwm lub lim tiam peb yuav mus tom kws kho mob. Tshaj tawm qhov txuas rau kab lus

Cov tshuaj yog muaj raws li kev ncua rau kev txhaj tshuaj hauv qab daim tawv. Cov tshuaj nquag yog insulin lispro 100 IU.

Cov tshuaj ntxiv hauv qhov muaj pes tsawg leeg:

1.76 mg metacresol,
0.80 mg ntawm phenol kua,
16 mg ntawm glycerol (glycerol),
0.28 mg provitamin sulfate,
3.78 mg ntawm sodium hydrogen phosphate,
25 mcg ntawm zinc oxide,
10% hydrochloric acid daws,
Txog li 1 ml ntawm dej rau kev txhaj tshuaj.

Cov tshuaj yog xim dawb nyob rau hauv cov xim, muaj peev xwm ua kom exfoliating. Qhov tshwm sim yog lub caij ntuj nag dawb thiab cov kua ntshiab ntshiab uas ntxiv rau hauv qhov nag lossis daus. Rau kev txhaj tshuaj, nws yog ib qhov tsim nyog los sib tov cov kua tsim nrog kev ua kom yoog los ntawm maj mam tuav cov ampoules. Humalog cuam tshuam txog txhais tau tias sib txuas cov analogues ntawm ntuj insulin nrog nruab nrab thiab luv ncua ntev ntawm kev nqis tes ua.

Sib tov 50 quicpen yog ib qho kev sib xyaw ntawm ntuj sai los ua insulin (insulin solution lispro 50%) thiab nruab nrab txiav txim (provitamin raug tshem tawm insulin lispro 50%).

Qhov kev tsom xam ntawm cov tshuaj no yog tswj cov kev zom zaub mov kom muaj suab thaj hauv lub cev. Cov ncauj lus anabolic thiab tiv thaiv catabolic hauv ntau lub hlwb ntawm lub cev puav leej raug sau tseg.

Lizpro yog cov tshuaj insulin, uas zoo sib xws rau cov tshuaj hormones tsim hauv tib neeg lub cev, txawm hais tias tag nrho cov ntshav qab zib cov ntshav tshwm sim sai dua, tab sis cov nyhuv kav ntev dua. Kev nqus ntawm cov ntshav thiab qhov pib ntawm qhov kev nqis tes ua ncaj qha nyob ntawm ntau yam:

qhov chaw txhaj tshuaj (nkag mus rau hauv plab, hips, pob tw),
ntau npaum (yuav tsum tau siv tshuaj insulin),
cov ntshav kev ua haujlwm
lub cev kub ntawm tus neeg mob
kev tawm dag zog lub cev.

Ua rau kev txhaj tshuaj, cov nyhuv ntawm cov tshuaj pib hauv 15 feeb tom ntej. Feem ntau, qhov kev ncua yog txhaj rau hauv qab daim tawv nqaij ob peb feeb ua ntej noj mov, uas yuav pab kom tsis txhob muaj cov kua nplaum duav ntxiv. Rau kev sib piv, qhov ua tau zoo ntawm lyspro insulin tuaj yeem sib piv los ntawm nws cov kev ua nrog tib neeg cov insulin - isophan, uas nws qhov kev txiav txim siab tuaj yeem ntev txog 15 teev.

Raws li kev tsim nyog rau kev siv cov tshuaj xws li Humalogmix 25, 50 thiab 100, cov lus qhia rau kev siv yuav tsim nyog. Nws yuav tsum tau nco qab tias cov tshuaj siv rau hauv ntshav qab zib mellitus rau kev kho mob ntawm cov neeg mob ntawm cov hnub nyoog sib txawv, rau lub neej ib txwm ntawm uas cov tshuaj insulin xav tau txhua hnub. Qhov yuav tsum tau txhaj ntau zaus thiab ntau zaus ntawm kev tswj hwm tsuas yog txiav txim los ntawm kws kho mob.

Nws muaj 3 txoj kev txhaj tshuaj:

Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!

Tsuas yog cov kws tshwj xeeb tuaj yeem muab cov tshuaj rau hauv cov chaw muaj mob. Qhov no yog vim qhov tseeb tias kev tswj hwm tus kheej ntawm cov tshuaj hauv txoj hauv kev no coj qee yam kev pheej hmoo. Cov insulin cartridge yog tsim los rov qab nqus cov ntawv xaum rau cov neeg mob ntshav qab zib. Taw qhia hauv txoj hauv kev no yog nqa tawm tshwj xeeb hauv qab daim tawv nqaij.

Qhov qhia tshuaj Chiv no yog nkag mus rau hauv lub cev hauv qhov siab ntev li 15 feeb. ua ntej noj mov, los sis ncaj qha li ib feeb tom qab noj mov. Qhov ntau zaus ntawm kev txhaj tshuaj tuaj yeem sib txawv ntawm 4 txog 6 zaug hauv ib hnub. Thaum cov neeg mob noj tshuaj insulin ntev, kev txhaj tshuaj txo tsawg dua 3 zaug hauv ib hnub. Nws yog txwv tsis pub tshaj qhov ntau tshaj qhov tau them los ntawm kws kho mob yog tias tsis muaj qhov mob xav tau sai.

Nyob rau hauv parallel nrog cov tshuaj no, lwm yam analogues ntawm lub cev ntuj kuj raug tso cai. Nws yog tswj hwm los ntawm kev sib xyaw ob yam khoom hauv ib leeg xaum, uas ua rau kev txhaj tshuaj yooj yim dua, yooj yim thiab nyab xeeb. Ua ntej kev txhaj tshuaj yuav pib, daim cartridge nrog cov tshuaj yuav tsum tov kom txog thaum tus, dov hauv xib teg ntawm koj txhais tes. Koj tsis tuaj yeem co thawv nrog cov tshuaj kom ntau, vim tias muaj kev pheej hmoo ntawm kev tsim npuas, cov lus qhia ntawm qhov tsis tsim nyog.

Cov kev qhia kwv yees cov nram qab no algorithm ntawm kev nqis tes, yuav ua li cas siv ntawm Humalogmix kom raug:

Ua ntej tshaj plaws, koj yuav tsum ntxuav koj txhais tes kom zoo, ib txwm siv xab npum.
Txheeb xyuas qhov chaw txhaj tshuaj, txhuam nws nrog daim ntawv caw cawv.
Nruab lub taub ntim hauv cov ntawv txhaj tshuaj, co maj mam mus rau ntau qhov kev qhia ntau zaus. Yog li cov tshuaj yeeb yaj kiab yuav nce tus yam ntxwv tsis sib thooj, ua pob tshab thiab tsis muaj xim. Tsuas siv cov roj cartridges nrog kua txheem tsis muaj huab seem.
Xaiv cov koob txhaj tshuaj rau kev tswj hwm.
Qhib lub koob txhaj los ntawm kev tshem lub hau.
Kho cov tawv nqaij.
Ntxig rau tag nrho cov koob txhaj tshuaj hauv qab daim tawv nqaij. Ua kom tiav qhov taw tes no, koj yuav tsum ua tib zoo kom tsis txhob nkag mus rau hauv cov hlab.
Tam sim no koj yuav tsum nias lub khawm, tuav cia.
Tos rau lub teeb liab kom ua tiav kev tswj hwm tshuaj los ua suab, suav 10 vib nas this. thiab rub tawm cov phwj hauv. Ua kom ntseeg tau tias cov koob xaiv tau raug tswj hwm tau ua tiav.
Tso cov ntawv caw cawv rau ntawm qhov chaw txhaj tshuaj. Nyob hauv ib qho xwm txheej twg yuav tsum koj tsis txhob nyem, txhuam lossis zaws ntawm qhov chaw txhaj tshuaj.
Kaw lub koob nrog lub hau tiv thaiv.

Thaum siv cov tshuaj, koj yuav tsum xav txog tias cov tshuaj hauv daim cartridge yuav tsum tau sov nyob hauv koj txhais tes mus rau chav sov ua ntej siv. Cov lus qhia hauv qab daim tawv nqaij nrog yeeb yaj kiab uas siv ib tus xaum xaum xaum yog nqa ntawm caj pas, xub pwg, hauv plab lossis pob tw. Nws raug nquahu kom tsis txhob txhaj rau tib qho chaw. Qhov chaw ntawm lub cev mus rau hauv cov insulin txhaj tshuaj txhua hli yuav tsum pauv hloov. Koj yuav tsum siv Humalog tsuas yog tom qab ntsuas ntsuas cov piam thaj nrog lub ntsej muag saib xyuas kom tsis txhob muaj kev txhim kho ntawm cov teeb meem.

Ntau tus neeg nyob nrog ntshav qab zib tau siv Humalogmix insulin 25, 50 thiab 100 rau ntau xyoo. Raws li, muaj ntau cov kev tshuaj xyuas, tab sis feem ntau zoo.

Kuv tau mob ntshav qab zib ntau dua 10 xyoo. Tsis ntev los no nrhiav tau Pom Humalog, uas tuaj yeem pricked nrog ib tug xaum xaum qhuav. Daim ntawv yooj yim rau kev taw qhia thiab ib txwm nyob ze. Txaus siab nrog kev ua sai ntawm cov tshuaj, uas tsis tas yuav tos ntev. Ua ntej rau qhov no, qhov sib xyaw ntawm Actrapid thiab Protafan tau txhaj, tab sis feem ntau tau cuam tshuam nrog kev mob ntshav qab zib. Thiab tib neeg qhia pab ua kom tsis nco qab txog qhov teeb meem.

Kuv tus ntxhais muaj mob ntshav qab zib hom 1 tau 3 xyoos. Txhua lub xyoo no tau nyob hauv qhov kev tshawb nrhiav ntawm cov tsheb nrawm. Nrog rau kev tshawb nrhiav rau cov tshuaj muaj yeeb tshuaj ntev, cov teeb meem zoo li no tsis tshwm sim. Ntawm cov tshuaj loj ntawm cov hom paub zoo, Humalog - Quickpein syringe mem - tau txais kev qhuas tshaj plaws. Qhov kev txiav txim tau zoo li ntxov tshaj li qhov so. Peb tau siv tshuaj yaj yeeb rau 6 lub hlis thiab tau tso tseg qhov kev tshawb fawb rau qhov zoo tshaj plaws.

Kuv muaj ntshav qab zib tau ntev. Kuv raug kev txom nyem los ntawm tas mus li thiab ntse spikes hauv qab zib. Tsis ntev los no, kws kho mob tau sau ntawv qhia txog Humalog. Tam sim no tus mob tau zoo tuaj lawm, tsis muaj cov tsis cuam tshuam los txiav txim siab dua. Qhov tsuas yog qhov uas tsis thov yog tus nqi siab.

Mob ntshav qab zib ib txwm ua rau neeg tuag taus. Muaj ntshav qab zib ntau dhau yog qhov txaus ntshai heev.

Alexander Myasnikov nyob rau lub Kaum Ob Hlis 2018 tau piav qhia txog kev kho mob ntshav qab zib. Nyeem tag nrho

Kev piav qhia cuam tshuam rau 31.07.2015

Lub npe Latin: Neej Neeg
ATX Code: A10AB04
Yam tshuaj muaj sia: Tshuaj insulin Lizpro
Chaw tsim tshuaj paus: Lilly Fabkis S. A. S., Fab Kis

Tshuaj insulin Lizpro, glycerol, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, hydrochloric acid (sodium hydroxide tov), dej.

Qhov kev daws teeb meem tsis muaj kob, muaj pob tshab hauv 3 ml cartridges hauv cov hlwv ntim rau hauv pob ntawv cardboard. 15.
Lub thawv ntim hauv QuickPen syringe mem (5) yog nyob hauv ib lub thawv ntawv.
Qhov tshuaj lom neeg Humalog Mix 50 thiab Humalog Mix 25 kuj tseem muaj. Insulin Humalog Mix yog sib xyaw kom muaj vaj huam sib luag ntawm Lizpro ua yeeb yam luv luv insulin thiab Lizpro insulin ncua nrog ncua ntev.

Cov tshuaj Insulin Humalog yog DNA hloov kho cov qauv ntawm cov tshuaj insulin. Cov yam ntxwv tshwj xeeb yog kev hloov pauv ntawm kev sib xyaw ntawm cov amino acids nyob rau hauv insulin B saw.

Cov tshuaj tswj cov txheej txheem piam thaj metabolism thiab muaj anabolic sivCov. Thaum qhia rau hauv tib neeg cov leeg nqaij, cov ntsiab lus nce ntxiv glycerol, glycogenfatty acids zoo dua protein ua kom sib haum, kev noj ntawm cov amino acids yog nce ntxiv, txawm li cas los xij, thaum lub sij hawm zuj zus gluconeogenesis, ketogenesis, glycogenolysis, lipolysistso tawm amino acidsthiab catabolism muaj protein ntau.

Yog tias muaj mob ntshav qab zib mellitus 1thiab 2hom ntawmnrog rau kev qhia ntawm cov tshuaj tom qab noj mov, muaj lus tshaj tawm hyperglycemiahais txog kev nqis tes ntawm tib neeg insulin. Lub sijhawm ntawm Lizpro nws txawv thiab nyob ntawm ntau yam - koob tshuaj, kub cev, qhov chaw txhaj tshuaj, ntshav ntshav, kev ua haujlwm ntawm lub cev.

Lizpro insulin cov thawj coj yog nrog los ntawm kev txo qis hauv cov ntu nocturnal hypoglycemia hauv cov neeg mob ntshav qab zib mellitus, thiab nws txoj kev ua piv nrog tib neeg cov tshuaj insulin tshwm sim sai dua (nruab nrab tom qab 15 feeb) thiab kav ntev dua (txij li 2 txog 5 teev).

Tom qab kev tswj hwm, cov tshuaj tau nrawm nrawm thiab nws qhov siab tshaj plaws hauv cov ntshav tau mus txog tom qab ½ - 1 teev. Hauv cov neeg mob nrog lub raum tsis ua hauj lwm ntau dua nqus tus nqi piv rau tib neeg tshuaj insulinCov. Ib nrab-lub neej yog li ib teev.

Ntshav qab zib mob ntshav Insulin-mellitus: pluag tsis zoo ua rau lwm yam tshuaj insulin, postprandial hyperglycemiame ntsis kho los ntawm lwm yam tshuaj, mob insulin zoo,

Mob ntshav qab zib mellitus: nyob rau hauv kis ntawm tsis kam mus rau tshuaj tiv thaiv kab mob, nrog haujlwmthiab kab mob ua rau chaw kho mob ntshav qab zib.

Hypersensitivity rau cov tshuaj, ntshav qog.

Kev mob ntshav qab zib yog qhov tshwm sim tseem ceeb vim yog qhov kev txiav txim ntawm cov tshuaj. Kev mob ntshav khov ntau heev tuaj yeem ua rau hypoglycemic coma (tsis nco qab), tshwj tsis yog qee kis, tus neeg mob yuav tau kom tuag.

Ua xua: ntau dua nyob rau hauv qhov kev tshwm sim hauv zos - khaus ntawm qhov chaw txhaj tshuaj, liab lossis o, lipodystrophyntawm qhov chaw txhaj tshuaj, tsis tshua muaj kev tsis haum tshuaj - ua pob khaus ntawm daim tawv nqaij, npaws, txo cov ntshav siab, tawm hws, angioedema, txog siav, tachycardia.

Cov koob tshuaj ntawm cov tshuaj tau teeb tsa ua ib tus zuj zus nyob ntawm qhov rhiab ntawm cov neeg mob mus rau tshuaj exogenous thiab lawv mob. Nws raug nquahu kom tswj cov tshuaj tsis pub dhau 15 feeb ua ntej lossis tom qab noj mov. Cov txheej txheem kev tswj hwm yog tus kheej. Ua li ntawd, tshuaj kub yuav tsum tau nyob theem theem.

Kev ua txhua hnub tuaj yeem sib txawv, muaj ntau qhov ntau rau 0.5-1 IU / kg. Nyob rau yav tom ntej, cov koob tshuaj txhua hnub thiab ib zaug ntawm cov tshuaj tau raug hloov kho nyob ntawm tus neeg mob metabolism thiab cov ntaub ntawv los ntawm ntau cov ntshav thiab cov zis ntsuas cov ntshav qabzib.

Kev tswj hwm kev siv tshuaj ntawm Humalog yog nqa tawm raws li kev txhaj tshuaj rau cov tshuaj tua kabmob. Kev txhaj tshuaj subcutaneous yog tsim nyob rau hauv lub xub pwg, pob tw, ncej puab lossis hauv plab, ntu hloov lawv thiab tsis pub siv qhov chaw ntau tshaj ib hlis ib zaug, thiab qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Thaum ua cov txheej txheem, yuav tsum tau saib xyuas kom tsis txhob nkag rau hauv cov hlab ntshav.

Tus neeg mob yuav tsum tau kawm cov txheej txheem txhaj tshuaj kom raug.

Kev noj tshuaj ntau dhau hwv tuaj yeem ua rau ntshav qognrog los lus muaj mob nkees, tawm hws, ntuav, apathytshee hnyo, tsis hnov mob, tachycardiamob taub hau. Nyob rau tib lub sijhawm, hypoglycemia tuaj yeem tshwm sim tsis yog hauv kev siv tshuaj ntau dhau, tab sis kuj yog qhov tshwm sim kev siv tshuaj insulin ntau ntxivtshwm sim los ntawm lub zog siv los noj. Ua raws li qhov mob hnyav ntawm lub qog ntshav qab zib, cov kev ntsuas tsim nyog yuav tau ua.

Kev txo lub plawv tsis zoo ntawm cov tshuaj yog txo qis tshuaj tiv thaiv qhov ncauj, Tshuaj cov thyroid hormones, GKS, Danazol, beta 2-adrenergic agonists, tricyclic cov tshuaj tiv thaiv kev ntxhov siab, tshuaj kho mob, Diazoxide, Isoniazid, Chlorprotixen, lithium carbonatederivatives phenothiazine, nicotinic acid.

Kev txo lub plawv tsis zoo ntawm cov tshuaj yog kho kom zoo anabolic tshuaj yuam, beta blockerstshuaj ethanol-muaj cov tshuaj Fenfluramine, tetracyclines, Guanethidine, MAO inhibitors, cov tshuaj tiv thaiv qhov ncauj hypoglycemic, salicylates, sulfonamides, ACE inhibitors, Octreotide.

Cov tshuaj tiv thaiv pej xeem tsis pom zoo kom sib xyaw nrog cov tsiaj tshuaj insulin, tab sis nws tuaj yeem raug tshuaj nyob rau hauv kev saib xyuas ntawm kws kho mob nrog kev ua haujlwm ntev ntawm tib neeg.

Tsis txhob khov rau hauv tub yees ntawm qhov kub ntawm 2 ° txog 8 ° C.

Perekrest S.V., Shainidze K.Z., Korneva E.A. Txheej txheem ntawm orexin-muaj cov neurons. Cov qauv thiab kev khiav dej num, ELBI-SPb - M., 2012. - 80 p.
Mob ntshav qab zib, Tshuaj - M., 2016. - 603 c.
Khoom noj uas kho ntshav qab zib. - M.: Qws tsev so ua si, 2011. - 608 c.

Cia kuv qhia kuv tus kheej. Kuv lub npe yog Elena. Kuv tau ua haujlwm li endocrinologist rau ntau tshaj 10 xyoo. Kuv ntseeg hais tias tam sim no kuv yog tus kws tshaj lij hauv kuv daim teb thiab kuv xav pab txhua tus neeg tuaj xyuas lub vev xaib kom daws qhov nyuaj thiab tsis yog li cov haujlwm. Txhua cov ntaub ntawv rau lub xaib tau sau thiab ua tib zoo ua kom tiav thiaj li xa ntau li ntau tau cov ntaub ntawv tsim nyog. Ua ntej thov cov ntaub ntawv uas tau piav qhia hauv lub vev xaib, yuav tsum tau sab laj nrog tus kws kho mob tshwj xeeb.