Diuver: cov lus qhia rau kev siv, analogues thiab tshuaj xyuas, tus nqi hauv cov khw muag tshuaj ntawm Russia

Cov ntsiav tshuaj yog milky dawb, puag ncig, biconvex nrog bevel ntawm ib sab thiab digital engraving ntawm lwm qhov, uas nws txawv nyob ntawm seb ntau npaum li cas ntawm cov khoom siv tseem ceeb. Ntau 5 mg torasemidesib raug tus lej 915, thiab 10 mg - 916 nyob rau sab nraum qab ntawm lub ntsiav tshuaj.

Cov tshuaj lag luam yog muag hauv cov hlwv ntim ntawm polymer zaj duab xis thiab txhuas ntawv ci, hauv txhua lub voj voog li 10 ntsiav tshuaj. Muaj ob daim paib hauv thawv ntawv thawv (20 daim ib lub thawv).

Pharmacological kev txiav txim

Diuver (INN - Diuver) Puas yog neeg siv yeeb tshuaj tso tawm, tso pawg voj voos txhawb zog tshuaj, uas yog, cov nyhuv tseem ceeb ntawm cov tshuaj yog tsom rau lub voj ntawm Henle (ib qho ntawm cov khoom siv tseem ceeb ntawm cov qauv ua haujlwm ntawm lub raum - nephron) Cov nyhuv feem ntau ntawm cov tshuaj pharmacological yog inhibition ntawm thim rov qab nqus ntawm sodium thiab chlorine ions nyob rau hauv lub hauv caug nce saum toj ntawm lub voj, uas yog manifested nyob rau hauv ib tug txo nyob rau hauv osmotic tsis muaj kua ntawm intracellular kua. Raws li qhov tshwm sim, nws yog qhov inhibited lub raum reabsorption dejniaj hnub nce ntxiv diuresis thiab cov kua dej dhau los yog tshem tawm los ntawm lub cev.

Cov txheej txheem ntawm kev ua ntawm kev npaj tshuaj yog nqa tawm los ntawm thaiv cov ion thauj nyob rau hauv apical ib feem ntawm lub qaum (lwm lub npe rau ntu yog tuab) ib feem ntawm lub kauj nephron. Receptors tseem thaiv aldosteronenyob hauv lub plawv leeg. Qhov no tso cai ntxivnce dej kom ntau ntxiv, txij li thaum lub cev qog noj ntawm cov qog adrenal tsis txhawb qhov thim rov qab nqus cov kua dej.

Lub plawv cia tso cai normalize diastolic myocardial muaj nuj nqi, Txij li thaum tshaj tawm nrog lub ntim ntau ntxiv yog tiv thaiv (lub ntsiab pathophysiological ua rau lub plawv valve tsis txaus thiab tom qab ntawd hypertrophy ntawm lub siab). Vim yog lub caij nyoog ntev ntawm myocardium thiab ntev dua diastole tsawg dua fibrosing thiab sclerosis cov leeg nqaij ntawm lub twj tso kua mis sab hauv.

Diuver tseem tuaj yeem ua tau antihypertensive tus neeg sawv cev, txij li qhov kev nqis tes ntawm Torasemide, lub ntsiab lus nquag ua haujlwm, yog pom tau hais tias vimtxo ntawm peripheral vascular tsis kam (overload tivthaiv, ua rau lub siab ua haujlwm ntxiv thiab, yog li ntawd, nce ntxiv ntshav siab) Tus txheej txheem ntawm qhov kev txiav txim no yog stimulation ntawm cov poov tshuaj ion kev ua si nyob rau hauv cov hlwb mos ntawm cov leeg txheej ntawm lub vascular txaj, vim hais tias lub phab ntsa teb rau cov kev cuam tshuam ntawm cov xov xwm lom tau tsawg dua (cov tshuaj endogenous, piv txwv li, kev ua noj ua hauslossis vasopressinkev loj hlob ntawm cov posterior pituitary caj pas).

Nws yog tsim nyog sau cia tias torasemidenyiam thiazide diuretic, muaj ib tug xov tooj ntawm cov zoo piv rau lub ntsiab tshuaj npaj ntawm qhov kev txiav txim no - Furosemide:

  • rau qhov tsawg dua me ntsis, muaj kab mob pathological xws li hypokalemia,
  • kev siv tshuaj yaj yeeb torasemide saum toj no
  • cov nyhuv exerted los ntawm Diuver yog ntau lub sijhawm ntev, uas tso cai rau kev kho lub sijhawm ntev nrog cov tshuaj no.

Pharmacodynamics thiab pharmacokinetics

Diuver yog txais lusceev thiab kuj tiav (kev noj qab nyob zoocov tshuaj yog 80-90 feem pua, nyob ntawm tus neeg cov yam ntxwv ntawm lub cev) yog adsorbed ntawm txoj hnyuv huam. Qhov ntshav siab tshaj plaws ntawm cov khoom siv nquag tau pom tom qab 1-2 teev, tom qab noj cov ntsiav tshuaj. Hauv cov ntshav torasemidekhi rau cov ntshav plasma protein, uas muab diuretic nyhuv tshaj kaum yim teev tom ntejCov. Qhov ntau zaus ntawm kev tso zis nce uniformly nyob rau tag nrho lub sijhawm ntawm cov tshuaj, uas yog tseeg tias qhov zoo ntawm cov tshuaj (tsis zoo li Furosemide, nws tsis yuam kom txwv tus neeg mob cov haujlwm tam sim ntawd tom qab noj cov ntsiav tshuaj).

Metabolizedtshuaj kho mob hauv lub siab, hauv qab qhov kev txiav txim ntawm cov enzymes hauv lub cev cytochrome P450Cov. Daim ntawv tshuaj lom neeg hydroxylated metabolitesuas khi rau cov ntshav plasma los ntawm 86-97 feem pua ​​(muaj txaus ntawm txoj kev sib khi nyob ntawm kev hloov pauv roj ntsha ntawm cov khoom sib txuas thiab ua ntu zus ntawm cov hlau oxidation thiab cov kauj vuam hydroxylation).

Yog qhiaDiuver tsuas yog los ntawm lub raum (lub raum tshem tawm torasemideyog 10 ml / min, tawm tsam tom qab ntawm tag nrho - 40 ml / min) nyob rau hauv daim ntawv ntawm lub cev tsis muaj zog, txog yim caum feem pua ​​ntawm ib koob tshuaj. Ib nrab-lub neej kev npaj tshuaj yog li 3-4 teev (yog tias lub raum tsis ua haujlwm, qhov ntsuas tsis txawv ib qho). Ib feem me me ntawm metabolites torasemideNws yog tawm los ntawm hemodialysis thiab hemofiltration.

Kev Taw Qhia Diuver

Qhov tseeb tshaj plaws rau kev siv cov tshuaj diuretic raws torasemideyog edematous mob siab tawm tsam keeb kwm ntawm ntau pathologies. Yog li ntawd nrog kab mob ntawm lub raum, mob siab, ntsws hauv kev kho ua txoj, nws muaj nqis nrog rau cov tshuaj ntawm kev ua zoo sib xws.

Mob plawv nres Nws tseem muaj txiaj ntsig ntau dua los kho yog tias muaj voj diureticspab txhawm rau txo cov kua dej kom ntau hauv cov kab noj hniav thiab cov ntaub so ntswg.

Kev taw qhia rau kev siv Diuver nrog leeg ntshav siab nws tsis yog qhov tseeb, tab sis feem ntau cov kws kho mob siv cov tshuaj no hauv kev siv tshuaj rau txoj kev kho mob, vim nws muaj qhov muaj zog thiab kav ntev dua piv rau lwm cov tshuaj diuretics. Qhov ua tau zoo ntawm Diuver txoj kev siv kuj yog nws qhov peev xwm pharmacokinetic thiab koob tshuaj nyhuvtso cai kom meej meej tswj qhov kev xav ua kom zoo.

Cov Yuav Tsum Muaj

  • lub cev tsis haum lossis qhov tsis haum rau cov tshuaj ntawm kev npaj tshuaj,
  • lub raum tsis ua haujlwm hauv anuria,
  • lactase tsis muaj peev xwm (thiab lactose tsis kam lees, vim yog qhov tshwm sim ntawm nws) lossis tsis muaj kev nqus ntawm qabzib thiab galactose,
  • lub cev qhuav dej, exicosishypovolemic tej yam kev mob,
  • hepatic tsis meej pem,
  • lub sijhawm kev pub mis,
  • qaug cawv mob glycosides,
  • cov lus hais hypokalemialossis tshuaj mob siab ntsws,
  • ntse glomerulonephritis,
  • decompensated lub plawv valve qhov tsis xws luag (tshwj xeeb stenosis ntawm aortic thiab mitral qhib),
  • nce central venous siab siab tshaj 10 mmHg,
  • hnub nyoog qeb mus txog 18 xyoo.

Tseem muaj ntau tus kab mob pathological thaum cov tshuaj yuav tsum raug saib xyuas tsuas yog nyob rau hauv kev saib xyuas ntawm cov kws tshaj lij hauv kev kho mob hauv chaw kho mob (yog li nrog kev txhim kho cov kev mob tshwm sim tsis zoo ntawm kev kho txoj kev kho, kev pab yuav tsum tau muab kev pab sai li sai tau). Cov mob no suav nrog:

  • arterial hypotension,
  • atherosclerosis (tshwj xeeb tshaj yog cov hlab ntsha hlwb),
  • predisposition kom nce ntshav plasma concentration ntawm urates,
  • kev ua txhaum ntawm cov zis tawm ntawm cov zis (qhov ua haujlwm feem ntau benign prostatic hyperplasia rau tus txiv neej lossis stenotic inflammatory txheej txheem hauv poj niam),
  • mob theem myocardial infarction (txoj kev pheej hmoo ntawm kev tsim cardiogenic poob siab thiab qhov kev vam meej ntawm cov txheej txheem pathological tseem loj hlob tuaj),
  • mob ntshav qab zib mellitus (txo cov piam thaj hauv kev siab ntawm lub hlwb thiab txo cov nyhuv hypoglycemic ntawm cov tshuaj),
  • anemia,
  • hepatorenal mob siab.

Sab sij huam

Cov tshuaj yuav ua rau cov kev mob tshwm sim hauv qab no thaum kho cov mob edema syndrome:

  • Los ntawm hlab plawv:mob circulatory tsis ua hauj lwmntev li hauv txo nyob rau hauv cov ntshav siab txog cev qhuav dej, arrhythmias (feem ntau yog tachycardia), txo qis hauv cov ntim ntawm cov ntshav ncig.
  • Los ntawm cov kab mob zis: mob tso zis ceev heevnce qhov ua hauj lwm ntau ntawm cov ntsev uric acid hauv cov ntshav ntshav, hematuria(ntshav hauv cov zis) interstitial nephritis, hydronephrosis.
  • Los ntawm VEB thiab KSCHB: qhov txo qis hauv cov ntshav cov ntsiab lus ntawm sodium, potassium, chlorine, magnesium, calcium, metabolic alkalosis, tshuaj hypovolemia, lub cev qhuav dej, exicosis, ntshav siabthiab nce rau hauv cov ntshav viscosity.
  • Los ntawm metabolism hauv: hypercholesterolemia, hypertriglyceridemia thiab atherosclerosisvim li ntawd, kev nce siab hauv kev mloog zoo ntawm creatinine thiab urea hauv cov ntshav, gouty kab mob, txo cov piam thaj hauv kev siab ntev (ua rau npau taws tau kev qhia ntshav qab zib).
  • Lub plab zom mov: Cov tsos mob dyspeptic (xeev siab) ntuav, mob epigastric, zawv plab), ua txhaum txoj haujlwm ntawm kev ua haujlwm ntawm daim siab enzymes, pancreatitis (feem ntau ntse).
  • Los ntawm cov leeg hauv nruab nrab thiab hnov cov plab hnyuv siab raum: reversible lub rooj sib hais tsis zoo, tinnitusmob taub hau kiv taub hau, paresthesia.
  • Daim tawv nqaij integument: urticaria, khaus tawvfocal ua pob, dermatitis, photosensitization, vasculitis, anaphylactic thiab anaphylactoid kev tsis haum (txog kev tsim kho kev ua xua poob siab).
  • Los ntawm peripheral ntshav: tus lej ntawm cov platelets thiab cov qe ntshav dawb tsawg zuj zus (tom kawg tshwm los agranulocytosis), aplastic lossis hemolytic anemia.

Diuver, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)

Tshuaj tua kab noj lusnrog dej me me. Nws raug nquahu kom siv cov tshuaj tam sim ntawd tom qab noj tshais, thaum adsorption hauv txoj hnyuv plab yog kho los ntawm pob tw zaub mov.

Kev noj tshuaj ntau yog npaj los ntawm tus kws kho mob mus koom rau hauv tus account tus yam ntxwv ntawm lub cev thiab cim rau kev rov ua kom zoo, feem ntau nrog edematous mob siab tshuaj kho mob ntawm ntau yam keeb kwm yog 5 mg torasemideib hnub. Maj mam, cov tshuaj txhua hnub tuaj yeem nce ntxiv mus rau 20 thiab txawm 40 mg nyob rau ib zaug, yog tias muaj kab mob pathological ntawm tus neeg mob yuav tsum tau. Txiav kev kho tsuas yog tom qab ploj ntawm edema (kom paub meej tias muaj cov txiaj ntsig zoo, tswj kev hnyav thiab McClure-Aldrich kev xeem zais zais).

Cov lus qhia rau kev siv Diuver nrog leeg ntshav siab sib txawv me ntsis. Thawj koob tshuaj yog 2.5 mg, uas yog, ib nrab ntawm lub ntsiav tshuaj nrog qhov loj torasemide5 mg (lossis peb lub hlis twg, feem, ntawm 10 mg ntawm cov tshuaj nquag ua haujlwm). Yog tias tsim nyog, ua kom cov nyhuv kho mob ntau dua, qhov koob tshuaj txhua hnub tuaj yeem nce txog 5 mg.

Noj ntau dhau

Kev nce ntshav ntau ntxiv nrog kev tswj tsis tau tswj hwm ntawm cov tshuaj ua rau cov tsos mob hauv qab no:

  • nquag tso zis tsawg zis kev nqus ntawm lub ntiajteb txawj nqus
  • ntau dhau circulatory deficiency,
  • cov lus txo hauv cov ntshav siab, nce mus txog orthostatic hypotension,
  • ua txhaum ntawm cov electrolyte thiab acid-puag qhov sib npaug ntawm lub cev,
  • lub plab zom zaws,
  • tsaug zog,
  • tsis meej pem,
  • cev qhuav dej- mob ntshav sai ua haujlwm.

Tshwj xeeb tshuaj tiv thaiv kab mob, uas yuav pab nrog Diuver kev qaug cawv hauv kev ua lag luam kws tshuaj, tab sis muaj cov kev kho kom zoo uas them rau cov mob pathological ntawm lub cev. Yog li cov nplua nuj siv Txoj kev lis ntshav kua ntshav isotonic thiab crystalline cov kev daws teeb meem los ua kom muaj kev ploj ntawm bcc. Raws li kev tswj hwm ntawm cov ntshav dej kom ntau ntawm electrolytes thiab hemocrit infused CBS cov neeg tswj hwm thiab VIBCov. Hauv cov xwm txheej nyuaj tshwj xeeb lawv tuaj yeem sivntshav hloov chaw thiab cov ntshav sib xyaw.

Yog tias siv tshuaj yeeb los tiv thaiv keeb kwm ntawm ib tus neeg nyuam qhuav noj ntau dua tshiab, tom qab ntawd siv tau pais plab lavage, ntuav provocation, kev khiav tawm ntawm cov ntsiab lus ntawm lub plab hauv txhua txoj kev ua tau (siv ob qho tib si kev saib xyuas, kev siv tshuaj kho mob, thiab cov hau kev ntawm kev siv lub cev ua haujlwm).

Kev sib txuam

Kev ntxaug- Ib qho tshuaj tiv thaiv tsis tshua muaj neeg nquag tuaj yeem cuam tshuam nrog kev siv tshuaj ntau. Yog li ib tug diuretic nce lub siab, thiab raws li kev pheej hmoo ntawm kev phiv thiab cov kev mob tshwm sim (tshwj xeeb tshaj yog oto- thiab nephrotoxicity) ntawm cov tshuaj xws li tshuaj tua kab mob pawg. cephalosporinthiab aminoglycosides, chloramphenicol, cisplatin, ethacrylic acid, amphotericin B (sib cuam tshuam li kev sib tw raum tsis zoo).

Nyias, nws tsim nyog sau cia tias Diuver txo qis kev ua haujlwmcov kab mob hypoglycemic, uas yuav tsum tau kho tsim nyog ntawm kev txuag kev saib xyuas mob ntshav qab zib. Lwm yam, kev tsim kho yog ua tau hyperglycemic lossis ketoacidotic coma thiab tsis hloov pauv hauv microvasculature. Cov nyhuv suav tshuaj kuj txo. allopurinolyog tias txoj kev kho mob ua ke ua cov tshuaj no nrog Torasemide-based diuretics.

Diuver yig txo qis raum kev ntshiab lithium npaj, Txij li thaum qhov ntau ntawm qhov ua kom tsis muaj zog ntawm cov zis yog zais cia (nrog cov kua muaj kua ntau ntxiv, lub ntsej muag ua haujlwm ntau lub zog tsis muaj zog). Qhov kev txiav txim no hem txoj kev loj hlob lithium intoxication, uas yuav tshwm sim raws li nram no:

  • Kev mob plab zom mov tsis haum (xeev siab, ntuav, thiab lwm yam)
  • nce neuromuscular kev tsis taus,
  • epileptic qaug dab peg thiab stupor,
  • ataxia,
  • loj tshee hnyo,
  • tsis meej pem, delirium,
  • lub raum tsis ua hauj lwm.

Cov tshuaj nonsteroidal anti-inflammatory txo txo ​​cov nyhuv diuretic torasemide, txij li thaum lawv inhibit synthesis prostaglandins, uas qhia tau nws tus kheej hauv kev ua txhaum ntawm cov kev ua ntawm xws li ib qho kev lom neeg li biologically tiv thaiv renin hauv ntshav ntshav Raws li qhov tshwm sim, lub raum cov ntshav poob qis thiab tso zis tsis ua haujlwm heev. Ib qho tseem ceeb ntawm kev ua haujlwm ntawm NSAIDs ua rau kom muaj txiaj ntsig hypotensive nyhuv tshuaj diuretic (renin- lub ntsiab lus tseem ceeb ntawm lub raum kev cai ntawm cov ntshav siab, exerting pressor nyhuv ntawm lub vascular txaj).

Nws yuav tsum tsis txhob koom ua ke hauv kev kho mob nyuaj thiab tshuaj uas tiv thaiv angiotensin-hloov pauv enzyme lossis angiotensin receptor agonists ua ke nrog voj diuretics, kev kho mob zoo li no tuaj yeem ua rau txo cov ntshav siab ntau ntxiv thiab txoj kev loj hlob ntawm cov mob ntshav tsis zoo kom tawg. Nrog qhov qhia tau tiag tiag, nws raug nquahu tias txoj kev kho kom zoo yuav tsum tau txo lossis txiav tawm ib ntus torasemide qhov ntawd.

Hauv cov neeg mob uas muaj feem yuav ua mob raum (nephropathyntau yam etiologies) yuav tsum zam cyclosporine thiab torasemide, vim tias qhov no tuaj yeem ua lub hauv paus rau qhov xwm txheej hnyav heev. Ib qho kev mob tshwm sim ntawm cyclosporin yog qhov ua txhaum ntawm kev nthuav dav ntawm cov ntsev uric acid los ntawm ob lub raum, thiab torasemide, nyeg, ua rau muaj kev nce ntxiv hauv lawv cov kev nkag siab hauv cov hlab ntshav. Xws li kev sib nrig sib yuav inevitably ua rau deposition ntawm urates lossis kev loj hlob ntawm gouty mob caj dab.

Cov lus qhia rau kev siv Diuver, haus ntau npaum

Cov tshuaj yog npaj rau hauv lub qhov ncauj. Cov ntsiav tshuaj tau noj thaum sawv ntxov tom qab noj tshais nrog ib qho kua me me.

Txog kev kho kab mob edematous syndrome, 1 ntsiav tshuaj ntawm Diuver 5 mg 1 lub sij hawm hauv ib hnub yog tshuaj. Yog tias tsim nyog, qhov tshuaj yuav tuaj yeem nce ntxiv mus rau 20-40 mg ib hnub ib zaug. Hauv qee qhov tshwj xeeb, qhov kev siv tshuaj txhua hnub yuav yog 200 mg.

Rau kev kho mob ntawm kev kub siab, ib nrab ib ntsiav tshuaj ntawm Diuver 5 mg (2.5 mg) 1 ib zaug hauv ib hnub yog tshuaj. Muaj qee kis, thaum kev txiav txim siab ntawm tus kws kho mob, ntau npaum li cas ntxiv tau nce txog 5 mg ib hnub twg.

Kev lees txais ntau dua 5 mg rau ib hnub twg tsis ua rau muaj kev txo ntshav siab ntxiv thiab tsis xav kom ua rau kev mob ntshav siab. Nws yuav tsum tau yug hauv siab tias qhov siab tshaj plaws kev ua haujlwm ntawm torasemide tiav 12 lub lis piam tom qab pib kho.

Cov neeg laus yuav tsum raug sau cia torasemide tsawg kawg kev noj thiab cov tshuaj txhaj kho nrog ceev faj.

Diuretic Diuver

Lub ntsiab ua haujlwm tseem ceeb hauv cov tshuaj yog torasemide, uas ua haujlwm ua cov diuretic uas muaj cov nyhuv ntev. Cov khoom siv ntxiv - cov hmoov txhuv nplej, lactose monohydrate, sodium carboxymethyl hmoov txhuv nplej siab. Nws muaj cov hlau nplaum magnesium stearate, anhydrous silicon dioxide. Cov tshuaj Diuver muaj kev taw qhia rau kev siv hauv puffiness, nws qhov kev txiav txim siab pab:

  • txo qis osmotic siab nyob rau hauv lub raum hlwb,
  • tshem tawm cov kua ntau ntawm cov ntaub so ntswg,
  • kev tsuj ntawm kev nqus ntawm dej, sodium ions,
  • txhim kho myocardial kev ua haujlwm,
  • ua kom cov poov xab rho tsawg,
  • txo cov leeg.

Diuver - kev qhia

Kev qhia rau kev siv tshuaj yog txiav txim los ntawm tus kws kho mob. Siv cov tshuaj Diuver, nws yog ib qho tsim nyog yuav tsum kawm cov lus qhia, uas qhia txog cov cai rau kev pub nkag, haus thiab pom zoo:

  • coj mus rau hauv tus account phiv, contraindications,
  • ua kev soj ntsuam ntshav tsis tu ncua
  • tib lub sijhawm haus Veroshpiron los khaws cia poov tshuaj,
  • ua raws li kev noj haus nrog kev siv ntev.

Raws li cov lus qhia rau kev siv, nws yog qhov tsim nyog:

  • ua ntej kev kho mob, kho cov dej-electrolyte tshuav nyiaj li cas,
  • kuaj xyuas ntshav qab zib rau ntshav qab zib,
  • siv cov khoom lag luam nrog ceev faj hauv ATP inhibitors - txo qhov txo qhov siab,
  • caiv txhob tsav tsheb,
  • haus poov tshuaj pab,
  • tshem tawm kev ua haujlwm nrog cov koog uas nyuaj.

Diuver - zaj lus tim khawv

Tom qab nyeem cov lus qhia, koj tuaj yeem nkag siab tias Diuver - kev qhia rau kev siv uas yog qhov tseeb ntawm edematous syndromes ntawm ntau yam keeb kwm, muaj cov nyhuv hauv ntau thaj chaw ntawm cov tshuaj. Cov tshuaj yog kws kho mob los ntawm kws kho mob thiab kws kho keeb, tus kws kho hlwb thiab kws kho plawv. Diuver ntsiav tshuaj muaj cov nyhuv rau cov kabmob:

  • raum
  • ntsws
  • mob siab
  • arterial tawg nyob rau hauv cov neeg laus,
  • mob plawv tsis ua hauj lwm.

Diuver - noj

Thaum teem cov Diuver - qhov ntsuas kev siv uas tau o, tus kws kho mob xub xaiv cov tshuaj me me. Thaum saib xyuas tus neeg mob, kev kho mob tau kho kom haum. Kev tswj hwm tus kheej ntawm diuretics yog qhov tsis tuaj yeem tsis txaus ntseeg vim muaj cov tshwm sim ntawm cov mob tshwm sim, contraindications. Cov tshuaj tau noj thaum sawv ntxov, tom qab noj mov, ntxuav nrog dej. Hauv qee kis, nws txoj kev siv lub neej yog qhov pom zoo. Thawj qhov tshuaj ntawm Diuver ib hnub:

  • nrog kub siab - 2.5 mg - ib nrab ib ntsiav tshuaj,
  • thaum mob ntsws, raum - 5 mg,
  • nrog lub plawv tsis ua haujlwm hnyav - txog 40 mg.

Diuver - contraindications

Lub diuretic yuav tsum tau siv nyob rau hauv kev saib xyuas ntawm tus kws kho mob, tsis yog tsuas yog vim cov tshuaj tseem ceeb tau ntxuav tawm hauv lub cev uas yuav tsum muaj kev soj ntsuam. Muaj cov contraindications Diuver:

  • lub raum tsis ua haujlwm, uas tso zis tsis nkag rau lub zais zis,
  • hepatic tsis meej pem
  • hyponatremia - ua kom cov ntsev tsawg zuj zus,
  • ua kom nrov nrov,
  • txo qis siab
  • lactose intolerance,
  • mob glomerulonephritis mob ntev.

Kev siv cov tshuaj thaum cev xeeb tub, menyuam yaus, cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo, thaum tseem pub niam mis noj tsis tau. Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm:

  • mob glycoside intoxication,
  • ua xua rau Cheebtsam,
  • nce siab venous siab
  • piam thaj kev tsis haum,
  • mob gout
  • mob myocardial infarction,
  • mob ntshav qab zib mellitus
  • anemia
  • kev ua txhaum ntawm outflow ntawm zis,
  • ventricular arrhythmias,
  • zawv plab.

Cov kws kho mob, paub txog tias diuver - kev taw qhia rau nws siv tsis tu ncua yog cov lus qhia, zoo rau kev kho mob, yuav tsum ua tib zoo xav txog kev phiv. Muaj cov tsis zoo li lub sijhawm los ntawm lub cev:

  • hlab plawv - lub siab poob, tsaus muag,
  • tso zis - tso zis cia, qhov tsos ntawm cov ntshav hauv nws, txo qis potency,
  • plab zom mov - raws plab, ntuav, exacerbation ntawm pancreatitis, tsis qab los,
  • poob siab - tinnitus, loog ntawm nqua, tsis pom kev zoo,
  • ntshav ncig - txo qis hauv cov ntshav liab, ua haujlwm tsis zoo ntawm cov kab ke.

Diuver - analogues

Lub xub ntiag ntawm cov kev txwv tsis pub muaj ntau tus kws kho mob tau sau ntawv rau cov neeg mob, thaum qhia rau siv, txhais ntawm cov diuretics uas muaj cov tshuaj zoo sib xws. Cov lus qhia radar pom zoo Diuver cov qauv sib piv nrog cov sib xyaw zoo sib xws:

  • Aquaphor,
  • Aldacton
  • Arifon Retard,
  • Britomar,
  • Brinerdin,
  • Brusniver,
  • Tshuaj Ntsuab,
  • Bufenox,
  • Isobar
  • Zokardis ntxiv rau,
  • Indresspress
  • Clopamide
  • Lorvas
  • Lespeflan
  • Xas Las
  • Rov
  • Nebilong N,
  • Trigrim
  • Triamtel
  • Spironolactone
  • Furosemide
  • Phytolysin.

Nqe rau Diuver

Cov tshuaj diuretics tuaj yeem tuaj yeem yuav tom khw muag khoom ntawm cov khw muag tshuaj ze. Tsuas yog xaj tshuaj los ntawm cov ntawv teev npe thiab yuav hauv khw online. Tus nqi nyob ntawm tus naj npawb ntawm cov ntsiav tshuaj hauv pob, cov chaw tsim khoom. Nqe rau Diuver thiab analogues:

Cov tshuaj nquag, mg

Tus nqi tawg, rubles

Kanefron H, rub

Ekaterina, 48 xyoo Torasemid Canon tau tsim los ntawm tus kws kho keeb endocrinologist, qhia tias siv yog mob nrawm heev. Nws tsis paub yuav mus kev li cas - nws ob txhais ceg tsis haum rau khau. Kuv nyiam tias yam tshuaj ntawd ua mob sib khuav xwb, tsis muaj kev ntxhuam tas li mus tso quav tso zis. Twb tau nyob rau hnub thib ob, puffiness pib dhau, thiab ib lub lim tiam tom qab pom - yuag pib. Kuv zoo siab kawg.

Eugenia, 58 xyoo Raws li tus neeg mob txoj kev siab ntsws dhau los ntawm kev paub, Kuv raug soj ntsuam tas li los ntawm kws kho mob. Ntawm cov tshuaj uas kuv tau muab tshuaj rau qhov mob niaj hnub, muaj cov diuretics. Thaum xub thawj kuv haus Acetazolamide, tab sis nws muaj tus nqi siab rau cov neeg laus, ces tus kws kho mob hloov nws nrog Indapamide. Cov tshuaj tsis pheej yig, ua kom lub zog ruaj khov, tsis muaj kev cuam tshuam los ntawm kev yaum.

Valentina, hnub nyoog 52 xyoo. Thaum kuv paub hais tias muaj lub plawv tsis ua hauj lwm lawm, lawv tau muab tshuaj kho Veroshpilakton. Tus kws kho mob tau piav qhia hais tias cov tshuaj no tsis tsuas yog tshem tawm cov kua dej uas nyob qis qis, tab sis kuj tiv thaiv cov poov tshuaj los ntawm leach, uas yog qhov tseem ceeb heev rau cores. Qhov loj tshaj plaws yog tias qhov o tuaj rau tag nrho lub cev tau dhau mus, txawm hais tias lub qhov muag ntawm lub ntsej muag tau pom.

Cov Tshuaj Pharmacokinetics

Tom qab lub qhov ncauj tswj hwm, torasemide sai sai thiab yuav luag txhua yam hauv lub plab zom mov. Qhov siab tshaj plaws ntawm torasemide nyob rau hauv cov ntshav ntshav yog pom 1-2 teev tom qab noj tom qab ib pluas noj. Bioavailability yog 80-90% nrog tus neeg me muaj kev hloov pauv.

Cov nyhuv diuretic siv sijhawm ntev txog 18 teev, uas ua rau kom lub siab ntev ntawm kev kho mob vim tias tsis ntuav heev hauv thawj teev tom qab noj cov tshuaj hauv, ua rau muaj kev cuam tshuam ntawm cov neeg mob.

Kev sib txuas lus nrog cov protein plasma ntau dua 99%. Cov pom tseeb ntawm kev faib khoom yog 16 liv.

Nws yog metabolized hauv lub siab siv isoenzymes ntawm cytochrome P450 system. Raws li kev ua tiav ntawm cov oxidation, hydroxylation, lossis cov nplhaib hloov pauv, peb cov metabolites yog tsim (M1, M3, thiab M5), uas khi rau cov ntshav plasma protein ntau npaum li 86%, 95%, thiab 97%, feem.

Ib nrab-lub neej (T1 / 2) ntawm torasemide thiab nws cov metabolites yog 3-4 teev thiab tsis hloov pauv ntawm kev mob raum tsis ua haujlwm. Kev tshem tawm tag nrho ntawm torasemide yog 40 ml / min, lub raum tshem tawm - 10 ml / min. Qhov nruab nrab, kwv yees li 83% ntawm cov koob tshuaj uas tau noj yog tawm los ntawm ob lub raum: tsis hloov pauv (24%) thiab feem ntau tsis muaj zog metabolites (Ml - 12%, M3 - 3%, M5 - 41%).

Hauv raum tsis ua haujlwm, T1 / 2 tsis hloov, T1 / 2 ntawm metabolites M3 thiab M5 nce. Torasemide thiab nws cov metabolites yog tawm me ntsis los ntawm hemodialysis thiab hemofiltration.

Nrog kev ua haujlwm ntawm daim siab, qhov ua haujlwm ntawm torasemide hauv cov ntshav ntshav nce vim tias qhov txo qis hauv cov metabolism hauv cov tshuaj hauv lub siab. Hauv cov neeg mob uas muaj lub siab lossis daim siab tsis ua hauj lwm T1 / 2 ntawm torasemide thiab M5 metabolite yog nce me ntsis, kev sib txuam ntawm cov tshuaj tsis zoo li.

Nrog saib xyuas

Arterial hypotension, stenosing atherosclerosis ntawm lub cerebral cov hlab ntsha, hypoproteinemia, ib qho kev mob siab rau hyperuricemia, ua tsis tiav cov ntshav tawm (benign prostatic hyperplasia, nqig ntawm lub qhov zis lossis hydronephrosis), keeb kwm ntawm ventricular arrhythmia, mob ntshav qab zib, mob ntshav qab zib, mob ntshav qab zib, ntau ntxiv mob ntshav qab zib mellitus (txo qis qabzib tsis haum), hepatorenal syndrome, gout, anemia, cev xeeb tub.

Sab sij huam

Raws li cov lus qhia rau kev siv, kev teem sijhawm ntawm Diuver (5/10 mg) tuaj yeem nrog cov tshuaj phiv:

  • lub cev qhuav dej thiab ua kom cov ntshav concentration ntawm cov poov tshuaj, magnesium, calcium, chlorine thiab sodium,
  • qhov tseem ceeb txo nyob rau hauv cov ntshav siab,
  • arrhythmias thiab tachycardia, tsis tshua muaj vau,
  • thaj tsam muaj nyob rau hauv cov concentration ntawm urea thiab cov cholesterol nyob rau hauv cov ntshav,
  • interstitial nephritis lossis mob tso zis ceev,
  • pancreatitis thiab dyspeptic cuam tshuam,
  • paresthesia
  • tsis hnov ​​lus ib ntus
  • hloov hauv daim duab ntshav mus txog hemolytic thiab aplastic anemia,
  • kev tsis haum tshuaj ntawm daim tawv nqaij, nrog rau kev ua kom poob siab.

Yog tias pom cov tsos mob tshwm sim qhia qhov pib ntawm kev phiv tshuaj, nws raug nquahu kom koj tsum tsis txhob noj cov tshuaj ua ntej sab laj nrog koj tus kws kho mob.

Cov nyhuv diuretic ntawm cov tshuaj kav ntev txog 18 teev, vim tias, nyob rau thawj teev tom qab nws txoj kev tswj hwm, tsis muaj kev nquag nquag tso zis, txwv cov neeg ua haujlwm.

Cov Yuav Tsum Muaj

Diuver yog contraindicated hauv pawg neeg mob hauv qab no:

  • Nrog rau kev nkag siab ntau ntxiv rau torasemide thiab / lossis sulfonamides, ntxiv rau cov neeg muaj zog ntawm cov tshuaj,
  • Hauv cov mob uas nrog nrog tso zis ntws tawm mus rau hauv lub zais zis,
  • Nyob rau hauv lub xeev ntawm hepatic coma, yog tus cwj pwm los ntawm kev ua tsis tiav ntawm lub hauv nruab nrab lub paj hlwb, uas yog vim qhov loj inhibition ntawm daim siab ua haujlwm,
  • Hauv ib lub xeev muaj koob,
  • Nrog raum tsis ua haujlwm, uas nrog cov tsos mob ntawm nce azotemia,
  • Nrog arterial hypotension,
  • Nrog arrhythmia.

Vim tias tsis muaj kev tshawb fawb soj ntsuam thaum lub sijhawm pub mis, nws tsis pom zoo rau cov poj niam uas pub niam mis. Tsis tas li, cov tshuaj tsis raug pom zoo rau cov menyuam yaus hnub nyoog qis dua 18, vim tias nws muaj kev nyab xeeb thiab ua haujlwm zoo rau pawg neeg mob no tseem tsis tau tsim.

Thaum cev xeeb tub, kev siv ntawm Diuver tsuas yog txiav txim siab nkaus xwb yog qhov xwm txheej xav tau ceev. Kev txais neeg mob yuav tsum tau ua nyob rau hauv cov koob tshuaj tsawg kawg nkaus, nyob rau hauv chaw nyob ruaj ruaj thiab nyob rau hauv kev saib xyuas ntawm kws kho mob uas muaj tus poj niam hauv kev mob plab ua haujlwm.

Kev saib xyuas tas li ntawm tus me nyuam hauv plab yog qhov tseem ceeb, txij li thaum nkag mus rau hauv nws cov ntaub so ntswg, torasemide provokes cuam tshuam hauv cov dej-electrolyte metabolism, zoo li thrombocytopenia.

Noj ntau dhau

Thaum noj tshuaj ntau dhau ntawm Diuver hauv cov neeg mob, nws muaj peev xwm los tsim kom muaj dej-electrolyte cuam tshuam, mob siab, mob taub hau, mob ntshav khov, tsis meej pem thiab vascular tsis txaus.

Tsis tas li ntawd, kev txhim kho ntawm lub plab zom mov tsis haum.

Cov tshuaj tiv thaiv tshwj xeeb tsis paub. Discontinuation ntawm kev siv tshuaj lossis txo cov tshuaj noj yog qhia. Nrog rau cov tsos mob hnyav ntawm kev siv ntau dhau, dej-electrolyte tshuav qhov raug kho thiab cov kev kho mob cov tsos mob tau kho.

Siv thaum cev xeeb tub thiab lactation

Torasemide tsis muaj teratogenic effect thiab fetotoxicity, nkag mus rau hauv qhov chaw ntawm lub plab, ua rau muaj kev cuam tshuam hauv dej-electrolyte metabolism thiab thrombocytopenia hauv tus me nyuam hauv plab.

Cov tshuaj Diuver thaum cev xeeb tub tuaj yeem siv tsuas yog cov txiaj ntsig rau leej niam outweighs qhov kev pheej hmoo rau tus me nyuam hauv qab tsuas yog kev saib xyuas ntawm tus kws kho mob thiab tsuas yog siv tsawg kawg nkaus xwb.

Kuj tsis paub meej tias torasemide kis mus rau niam mis tau licas. Yog tias nws yog qhov yuav tsum tau siv cov tshuaj Diuver thaum lactation, nws yog ib qho tsim nyog kom tsis txhob pub mis niam.

Cov qauv ntawm Diuver, tus nqi hauv cov chaw muag tshuaj

Yog tias tsim nyog, Diuver tuaj yeem hloov nrog ib qho analogue ntawm cov tshuaj nquag - cov no yog cov tshuaj:

Thaum xaiv cov tshuaj analogues, nws yog ib qho tseem ceeb kom nkag siab tias cov lus qhia rau kev siv ntawm Diuver, tus nqi thiab tshuaj xyuas cov tshuaj uas muaj cov teebmeem zoo sib xws tsis siv. Nws yog ib qho tseem ceeb kom kws kho mob sab laj thiab tsis txhob hloov pauv cov tshuaj ywj siab.

Tus nqi hauv cov khw muag tshuaj ntawm Lavxias: Diuver ntsiav tshuaj 5 mg 20 pcs. - los ntawm 335 txog 391 rubles, 10 mg 20 pcs. - los ntawm 425 txog 439 rubles.

Khaws ntawm qhov kub thiab txias mus txog 30 ºС. Khaws tsis ncav cuag ntawm cov menyuam yaus. Txee lub neej yog 3 xyoos. Cov chaw muag tshuaj yog muag los ntawm cov tshuaj noj.

3 kev xyuas rau “Diuver”

Nws tshem tawm edema thiab txo qhov siab, tab sis muaj cov kev tsis zoo txaus ntshai (((

Tsis zoo li cov nqi sib tw kim dua, Diuver muaj ntau cov kev mob tshwm sim.

Kev kho mob zoo Diuver raug coj los ntawm kuv txiv vim yog lub plawv tsis ua kom tau txais kev tshem tawm ntawm kev mob siab rau ntau dhau (nws ob txhais ceg tau o loj, nws mus txog qhov uas nws tsis tuaj yeem txav nws tus kheej). Ua ntej Diuver, lawv tau sim txhua yam, tab sis tsis muaj ib qho pom tseeb thiab xav tias yuav ua tau zoo.

Diuver, cov lus qhia rau siv: txoj kev thiab qhov ntau npaum li cas

Diuver ntsiav tshuaj yuav tsum tau noj qhov ncauj 1 zaug nyob rau ib hnub (tom qab noj tshais), ntxuav nrog cov dej txaus.

Pom zoo ib zaug (thiab txhua hnub nyob rau tib lub sijhawm) cov koob tshuaj:

  • Edema syndrome: thawj koob tshuaj yog 5 mg, yog tias cov txiaj ntsig tsis txaus, qhov koob tshuaj tau nce ntxiv txog 20-40 mg, qee kis - txog 200 mg. Nws yog ib qho tsim nyog yuav tsum coj Diuver kom txog thaum lub edema ploj, kev kho mob ntev yog ua tau,
  • Arterial hypertension: thawj koob tshuaj yog 2.5 mg (1/2 ntsiav tshuaj), yog tias tsim nyog, nce qhov koob rau 5 mg.

Cov lus qhia tshwj xeeb

Diuver yuav tsum tau coj nruj raws li tus kws kho mob tau qhia.

Cov nyhuv diuretic ntawm Diuver kav ntev txog 18 teev, vim qhov ntawd, hauv thawj teev tom qab nws txoj kev tswj hwm, tsis muaj kev nquag nquag tso zis, txwv cov neeg ua haujlwm.

Thaum noj tshuaj Diuver siab rau lub sijhawm ntev, kev pheej hmoo ntawm kev txhim kho hypokalemia, hyponatremia thiab metabolic alkalosis nce ntxiv, thiab yog li ntawd nws tau pom zoo kom ua raws li kev noj zaub mov nrog sodium sodium chloride txaus thiab ntxiv rau noj potassium npaj.

Hauv cov neeg mob uas lub raum tsis txaus, txoj kev pheej hmoo ntawm kev tsim cov dej-electrolyte tshuav kev cuam tshuam yog nce, yog li ntawd, thaum kho, tswj lub siab ntawm cov electrolytes hauv cov ntshav ntshav (suav nrog sodium, potassium, calcium thiab magnesium), acid-base xeev, residual nitrogen, uric acid yog qhov tsim nyog thiab creatinine. Muaj qee kis, kev kho mob kom tsim nyog yuav tsum tau, tshwj xeeb yog cov neeg mob uas ntuav nquag los yog tau txais kua dej ntau dhau.

Nyob rau hauv cov ntaub ntawv ntawm qhov tsos lossis ntxiv dag zog ntawm oliguria thiab azotemia hauv cov neeg mob uas muaj mob hnyav raum mob, kev kho nrog Diuver pom zoo kom raug ncua.

Kev xaiv ntawm cov tshuaj Diuver tsim nyog rau cov neeg mob uas muaj ascites uas tsim los ntawm kev mob qog ntawm daim siab yuav tsum tau nqa tawm hauv tsev kho mob, txij li kev cuam tshuam hauv lawv cov dej-electrolyte tshuav nyiaj tuaj yeem ua rau muaj kev txhim kho ntawm hepatic tsis nco qab. Ib qho ntxiv, hauv pawg no ntawm cov neeg mob, ntshav ntshav yuav tsum tau kuaj xyuas tsis tu ncua.

Hauv cov neeg mob uas txo qis ntshav qabzib thiab ntshav qab zib, nws yog ib qho tsim nyog yuav tsum tau soj ntsuam tas li cov kev ntsuas ntawm cov piam thaj hauv cov zis thiab ntshav.

Vim txoj kev pheej hmoo ntawm kev tso zis ceev, tswj cov zis tso zis yog qhov tsim nyog rau cov neeg mob nrog txoj kev nqaim thiab cov prostatic hyperplasia, ntxiv rau cov neeg mob hauv lub xeev tsis nco qab lawm.

Cev xeeb tub thiab lactation

  • Cev xeeb tub: Diuver tuaj yeem siv nrog kev ceev faj nyob rau hauv kev txhaj tshuaj tsawg kawg tom qab ntsuas qhov piv ntawm cov txiaj ntsig uas xav tias yuav raug rau cov kev pheej hmoo uas twb muaj lawm, torasemide tsis muaj teebmeem teratogenic thiab fetotoxicity, nkag mus rau qhov tsis muaj teeb meem, uas ua rau thrombocytopenia thiab cov dej tsis haum-cov kab mob ntshav hauv lub plab,
  • Lactation: kev kho yog contraindicated.

Yeeb tshuaj sib cuam tshuam

  • Aminoglycosides, cephalosporins, ethacrylic acid, amphotericin B, chloramphenicol, cisplatin: lawv qhov kev tsom xam thiab kev pheej hmoo ntawm kev txhim kho oto- thiab nephrotoxic cov teebmeem nce ntxiv
  • Theophylline, diazoxide, cov tshuaj tiv thaiv kev tiv thaiv: lawv cov nyhuv yog ua kom zoo dua,
  • Siv cov leeg ua kom ib ce nqaij (piv txwv li, suxamethonium): lawv cov leeg ntawm neuromuscular yog txhim kho,
  • Cov kev ua kom cov leeg ua kom lub cev tsis ua haujlwm (xws li tubocurarine), allopurinol, hypoglycemic agents: lawv cov hauj lwm tsawg dua,
  • Torasemide, pressor amines: ib qho kev sib nrig sib txo kom cov txiaj ntsig raug sau tseg,
  • Cov tshuaj uas thaiv cov tubular ua kom sib xyaw: nce siab ntxiv kom to taub qhov quav,
  • Kev npaj lithium: lawv lub raum tshem tawm thiab qhov ntxim nyiam ua kom qaug tshuaj,
  • Cyclosporine: muaj kev pheej hmoo ntawm kev tsim muaj mob gouty mob caj dab,
  • Amphotericin B, glucocorticosteroids: muaj peev xwm ntau ntxiv ntawm kev txhim kho hypokalemia,
  • Mob glycosides: kev pheej hmoo ntawm kev tsim glycoside intoxication vim yog hypokalemia thiab ntev rau ib nrab-lub neej,
  • Sucralfate, cov tshuaj tsis yog tshuaj steroidal: cov diuretic nyhuv ntawm Diuver txo,
  • Salicylates hauv kev txhaj tshuaj ntau: qhov kev pheej hmoo ntawm kev siv tshuaj lom neeg ntau ntxiv,
  • Angiotensin-hloov ua enzyme inhibitors, angiotensin II receptor antagonists: muaj zog txo cov ntshav siab tau,
  • Methotrexate, probenecid: lawv lub raum txo qis, qhov ua tau zoo ntawm torasemide tsawg dua.

Hauv cov neeg mob uas muaj kev pheej hmoo siab ntawm kev mob nephropathy uas tau noj Diuver, thaum cov neeg ua pa radiopaque tau txais kev pabcuam, lub raum tsis ua haujlwm ntau dua li cov neeg mob uas muaj kev pheej hmoo ntawm nephropathy uas tau tso dej haus ua ntej tswj hwm ntawm radiopaque.

Cov cim ntawm Diuver yog: Torasemide, Torasemide-SZ, Torasemide Vertex, Trigrim, Trifas, Britomar.

Kev txheeb xyuas txog Diuver

Kev txheeb xyuas txog Diuver feem ntau zoo. Cov neeg mob tus yam ntxwv ua rau nws ua lub siab ntev dhau los ua cov diuretic, maj mam thiab maj mam tshem tawm cov kua dej ntau dhau, uas ua rau muaj kev cuam tshuam ntawm ceg tawv nqaij thiab ua rau ntshav nce siab. Tsis tas li ntawd, qhov ua tau ntawm lub sijhawm ntev ntawm kev siv tshuaj yaj yeeb yog suav tias yog qhov zoo. Tus nqi kwv yees siab.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Diuver muaj nyob rau hauv cov qauv ntawm cov ntsiav tshuaj dawb ntawm ib puag ncig biconvex duab, uas muaj kev pheej hmoo sib faib ntawm ib sab thiab kos rau ntawm lwm yam. Lub ntsiab tseem ceeb sib xyaw ntawm cov tshuaj yog torasemide, nws cov ntsiab lus yog hauv ntsiav tshuaj nrog engraving:

Cov chaw kho mob thiab chaw muab tshuaj: diuretic.

Dab tsi pab Diuver?

Ua raws li cov lus qhia, Diuver pom zoo rau cov neeg mob uas muaj kev mob tshwm sim ntawm edema syndrome vim tias mob plawv tsis ua haujlwm, kab mob ntawm lub raum, ntsws thiab mob siab.

Sab sij huam

Nrog rau kev siv cov tshuaj kom zoo thiab soj ntsuam qhov koob tshuaj pom zoo los ntawm tus kws kho mob, cov kev mob tshwm sim hauv cov neeg mob tshwm sim hauv qee qhov tsis tshua muaj. Nrog rau ib tug neeg lub cev tsis nco qab lossis siv tsis tau tswj, cov kev mob tshwm sim txuas ntxiv tuaj:

  • Los ntawm ib sab ntawm dej-electrolyte thiab acid-puag qhov tshuav: hyponatremia, hypochloremia, hypokalemia, hypomagnesemia, hypocalcemia, metabolic alkalosis. Cov tsos mob uas qhia txog kev txhim kho ntawm electrolyte thiab acid-puag ua haujlwm tuaj yeem suav nrog mob taub hau, tsis meej pem, cramps, tetany, leeg tsis muaj zog, mob plawv thiab mob plab tsis ua hauj lwm, hypovolemia thiab lub cev qhuav dej (ntau zaus hauv cov neeg laus), uas tuaj yeem ua rau hemoconcentration nrog ib qho kev nyiam ntawm mob thrombosis.
  • Los ntawm cov hlab plawv: ntau dhau los txo cov ntshav siab, orthostatic hypotension, tsaus muag, tachycardia, arrhythmias, qhov txo qis hauv cov ntshav ntawm cov ntshav ncig.
  • Los ntawm ib sab ntawm cov metabolism: hypercholesterolemia, hypertriglyceridemia, ib qho kev hloov pauv zuj zus hauv cov concentration ntawm creatinine thiab urea hauv cov ntshav, kev nce siab hauv cov concentration ntawm uric acid nyob rau hauv cov ntshav, uas tuaj yeem ua rau lossis nce cov tsos mob ntawm gout, ib qho kev txo qis ntawm qabzib kam (ua tau tshwm sim ntawm mob ntshav qab zib mellitus).
  • Los ntawm cov kab mob tso zis: oliguria, mob tso zis ceev heev (piv txwv li, nrog prostatic hyperplasia, nqaim ntawm lub qhov zis, hydronephrosis), interstitial nephritis, hematuria, txo potency.
  • Los ntawm kev mob plab zom mov: xeev siab, ntuav, raws plab, mob cholestasis intrahepatic, ntau ntxiv kev ua haujlwm ntawm "daim siab" enzymes, mob leeg mob ntsig txog leeg.
  • Los ntawm cov hlab ntsha hauv nruab nrab, hnov ​​cov khoom hauv lub cev: hnov ​​lus tsis zoo, feem ntau thim rov qab, thiab / lossis tinnitus, tshwj xeeb tshaj yog nyob rau cov neeg mob raum tsis ua haujlwm lossis hypoproteinemia (nephrotic syndrome), paresthesia.
  • Ntawm daim tawv nqaij: tawv nqaij khaus, urticaria, lwm yam kev tawm pob lossis tawv nqaij tawv nqaij, tawv nqaij orythema, exfoliative dermatitis, purpura, kub taub hau, vasculitis, eosinophilia, photosensitivity, loj anaphylactic lossis anaphylactoid tshua tau piav txog tam sim no uas tsuas tau piav qhia rau hnub no. tom qab tswj hwm cov leeg.
  • Los ntawm cov ntshav peripheral: thrombocytopenia, leukopenia, agranulocytosis, aplastic lossis hemolytic anemia.

Muaj qee zaus, kev poob siab anaphylactic kuj yuav tshwm sim.

Cov chaw muag tshuaj

Diuver yog diuretic thiab muaj kev tshaj tawm lub suab kom hnov ​​qab thiab diuretic ua rau lub cev. Cov tshuaj nquag ntawm cov tshuaj xyaum tsis ua rau kev loj hlob ntawm hypokalemia, nyob rau hauv sib piv rau furosemide thiab lwm yam analogues ntawm cov tshuaj.

Tom qab noj cov tshuaj hauv sab hauv, cov tshuaj nquag yuav nqus mus rau hauv cov ntshav dav dav, cov txiaj ntsig kho ntawm cov tshuaj tau pom tom qab 2 teev. Cov tshuaj tau txais txiaj ntsig zoo los ntawm cov neeg mob, yog li nws tuaj yeem siv ntev ntev yog tias tsim nyog.

Thaum cev xeeb tub

Thaum cev xeeb tub, kev siv ntawm Diuver tsuas yog txiav txim siab nkaus xwb yog qhov xwm txheej xav tau ceev. Kev txais neeg mob yuav tsum tau ua nyob rau hauv cov koob tshuaj tsawg kawg nkaus, nyob rau hauv chaw nyob ruaj ruaj thiab nyob rau hauv kev saib xyuas ntawm kws kho mob uas muaj tus poj niam hauv kev mob plab ua haujlwm. Kev saib xyuas tas li ntawm tus me nyuam hauv plab yog qhov tseem ceeb, txij li thaum nkag mus rau hauv nws cov ntaub so ntswg, torasemide provokes cuam tshuam hauv cov dej-electrolyte metabolism, zoo li thrombocytopenia.

Cia Koj Saib