Cov lus qhia rau kev siv tshuaj Torvacard thiab nws cov analogues

Hauv kev kho mob ntshav qab zib, tsis tsuas yog cov tshuaj uas cuam tshuam rau cov piam thaj hauv ntshav tau siv.

Ntxiv rau cov no, koj tus kws kho mob tuaj yeem sau tshuaj noj kom pab txo cov roj tsawg.

Ib cov tshuaj zoo li no yog Torvacard. Koj yuav tsum nkag siab tias nws yuav pab tau li cas rau cov mob ntshav qab zib thiab kev siv nws li cas.

Cov ntaub ntawv dav dav, muaj pes tsawg leeg, tso tawm daim ntawv

Thaiv Txhaws Roj Statin Thaiv

Cov cuab yeej no yog ib qho ntawm cov statins - tshuaj noj kom ntshav qis. Nws lub luag haujlwm tseem ceeb yog txo qis qhov kev xav ntawm cov rog hauv lub cev.

Nws siv tau zoo los tiv thaiv thiab tawm tsam atherosclerosis. Ib qho ntxiv, Torvacard tuaj yeem txo cov piam thaj hauv cov ntshav, uas yog cov txiaj ntsig zoo rau cov neeg mob uas muaj kev pheej hmoo ntawm kev mob ntshav qab zib.

Lub hauv paus ntawm cov tshuaj yog cov tshuaj Atorvastatin. Nws nyob rau hauv kev sib xyaw nrog cov khoom sib ntxiv ntxiv kom ua tiav cov hom phiaj.

Nws yog tsim nyob rau hauv lub Czech koom pheej. Koj tuaj yeem yuav cov tshuaj tsuas yog hauv cov qauv hauv cov ntsiav tshuaj. Txhawm rau ua qhov no, koj xav tau daim ntawv qhia los ntawm koj tus kws kho mob.

Cov nquag muaj kev cuam tshuam ntau yam ntawm tus neeg mob tus mob, yog li ntawd kev coj tus kheej nrog nws yog qhov tsis lees txais. Nco ntsoov tias tau txais cov lus qhia ib yam nkaus.

Cov tshuaj no tau muag hauv cov qauv hauv ncoo. Lawv cov khoom xyaw nquag yog Atorvastatin, qhov ntau hauv ib chav tuaj yeem yog 10, 20 lossis 40 mg.

Nws yog ntxiv los ntawm cov koom haum pabcuam uas pab txhawb qhov kev ua tau zoo ntawm Atorvastatin:

• magnesium oxide
• microcrystalline cellulose,
• silicon dioxide
• croscarmellose sodium,
• lactose monohydrate,
• magnesium stereate,
• hydroxypropyl cellulose,
• talcum hmoov
• macrogol
• titanium dioxide
• hypromellose.

Cov ntsiav tshuaj muaj lub puab puag ncig thiab dawb (lossis yuav luag dawb) xim. Lawv muab tso rau hauv cov hlwv ntawm 10 pcs. Cov pob tuaj yeem tuaj yeem nruab nrog 3 lossis 9 lub hlwv.

Cov chaw muag tshuaj thiab tshuaj pharmacokinetics

Qhov kev ua ntawm atorvastatin yog ua rau inhibit qhov enzyme uas coj los ua haujlwm ntawm cov cholesterol. Vim qhov no, cov roj (cholesterol) txo qis.

Cholesterol receptors pib ua ntau yam, vim qhov uas cov compound nyob rau hauv cov ntshav yuav noj sai dua.

Qhov no txwv tsis pub tsim ntawm atherosclerotic tso nyiaj rau hauv cov hlab. Tsis tas li ntawd, nyob rau ntawm cawv ntawm Atorvastatin, qhov kev txiav txim ntawm triglycerides thiab piam thaj txo.

Torvacard muaj cov txiaj ntsig sai. Cov cawv ntawm nws cov khoom siv tau mus txog rau nws cov kev siv nyiaj ntau tshaj tom qab 1-2 teev. Atorvastatin yuav luag txhua txoj hlua khi rau cov ntshav protein.

Nws cov metabolism hauv lub siab tshwm sim nrog kev tsim cov khoom noj tshwj xeeb. Nws siv sijhawm 14 teev los tshem tawm nws. Cov tshuaj tawm hauv lub cev nrog bile. Nws cov nyhuv mob tsawv rau 30 teev.

Kev taw qhia thiab contraindications

Torvacard raug pom zoo nyob rau hauv cov xwm txheej hauv qab no:

• cov roj (cholesterol) siab
• nce triglycerides
• hypercholesterolemia,
• kab mob plawv nrog rau kev pheej hmoo ntawm cov hlab plawv plawv,
• qhov ntxim nyiam ntawm theem nrab myocardial infarction.

Tus kws kho mob tuaj yeem sau tshuaj rau hauv lwm qhov xwm txheej, yog tias nws txoj kev siv yuav pab txhim kho txoj kev noj qab haus huv ntawm tus neeg mob.

Tab sis rau qhov no nws yog qhov tsim nyog tias tus neeg mob tsis muaj cov yam ntxwv li hauv qab no:

• mob rau daim siab hnyav
• lactase tsis muaj peev xwm
• lactose thiab piam thaj tsis pub haus,
• hnub nyoog qis dua 18 xyoo
• intolerance mus rau Cheebtsam
• cev xeeb tub
• ntuj pub mis.

Cov nta no yog contraindications, vim tias qhov uas siv ntawm Torvacard yog txwv tsis pub.

Tsis tas li, cov lus qhia tau hais txog tus neeg mob thaum koj tuaj yeem siv cov cuab yeej no nrog kev saib xyuas mob tas li xwb:

• quav cawv
• leeg ntshav siab
• qaug dab peg
• metabolic ntshawv siab
• mob ntshav qab zib mellitus
• sepsis
• raug mob hnyav lossis phais mob loj.

Hauv cov xwm txheej zoo li no, cov tshuaj no yuav ua rau muaj kev tsis haum siab, yog li yuav tsum tau ceev faj.

Cov lus qhia rau kev siv

Tsuas yog tswj hwm qhov ncauj ntawm cov tshuaj yog xyaum. Raws li cov lus qhia dav dav, thaum thawj theem koj yuav tsum haus cov tshuaj hauv qhov ntau npaum li 10 mg. Cov kev ntsuam xyuas txuas ntxiv tau coj tawm, raws li cov txiaj ntsig tau los ntawm tus kws kho mob tuaj yeem nce qhov koob tshuaj rau 20 mg.

Qhov nyiaj ntau ntawm Torvacard ib hnub yog 80 mg. Qhov zoo tshaj plaws yog txiav txim siab ntawm tus kheej rau txhua kis.

Ua ntej siv, ntsiav tshuaj tsis tas yuav tsum zuaj. Txhua tus neeg mob nqa lawv ntawm lub sijhawm zoo rau nws tus kheej, tsis tsom mus rau khoom noj, vim tias kev noj mov tsis cuam tshuam qhov tshwm sim.

Lub sijhawm kho yuav txawv. Ib qho txiaj ntsig yuav dhau los ua kom pom tom qab 2 lub lis piam, tab sis nws yuav siv sijhawm ntev heev los ua kom rov zoo li qub.

Zaj dab neeg video los ntawm Dr. Malysheva txog statins:

Cov Neeg Mob Tshwj Xeeb thiab Cov Lus Qhia

Rau qee tus neeg mob, cov tshuaj ua haujlwm hauv cov tshuaj yuav ua tau txawv txawv.

Nws siv yuav tsum tau ceev faj txog cov pawg hauv qab no:

1. Cov poj niam cev xeeb tub. Thaum lub sijhawm ua haujlwm ntawm tes, cov roj (cholesterol) thiab cov tshuaj uas cuam tshuam los ntawm nws yog qhov tsim nyog. Yog li, kev siv atorvastatin rau lub sijhawm no yog qhov txaus ntshai rau tus menyuam uas muaj kev loj hlob tsis zoo. Yog li, cov kws kho mob tsis pom zoo kom kho cov tshuaj no.
2. Cov niam xyaum kev xyoob ntoo pub mis. Cov tshuaj ua haujlwm nquag ntawm cov tshuaj kis mus rau niam mis, uas yuav cuam tshuam rau kev noj qab haus huv ntawm tus menyuam. Yog li, kev siv Torvacard thaum pub mis niam yog txwv tsis pub.
3. Menyuam yaus thiab tub ntxhais hluas. Yuav ua li cas Atorvastatin ua rau lawv tsis paub meej. Txhawm rau zam kev pheej hmoo txaus ntshai, kev teem sij hawm tshuaj no tsis suav nrog.
4. Cov neeg ntawm qub. Cov tshuaj muaj feem rau lawv ib yam nkaus li lwm tus neeg mob uas tsis muaj kev sib kis ntawm nws txoj kev siv. Qhov no txhais tau hais tias rau cov neeg laus laus tsis tas yuav ntau qhov hloov kho.

Tsis muaj lwm yam kev ceev faj rau cov tshuaj no.

Lub hauv paus ntsiab lus ntawm kev kho mob kev ua yog cuam tshuam los ntawm xws li ib qho ua raws li concomitant pathologies. Yog tias muaj, qee zaum yuav tsum tau ceev faj dua hauv kev siv tshuaj yeeb.

Rau Torvacard, xws li pathologies yog:

1. Lub siab ua mob rau daim siab. Lawv lub xub ntiag yog nyob rau ntawm cov lus tsis sib haum rau kev siv cov khoom.
2. Ntxiv kev ua si ntawm kev hloov ntshav hloov ntshav. Qhov tshwj xeeb ntawm lub cev no tseem ua haujlwm yog lub laj thawj rau qhov tsis kam noj tshuaj.

Kev tsis sib haum xeeb hauv kev ua haujlwm ntawm lub raum, uas feem ntau muaj nyob rau hauv cov npe ntawm contraindications, tsis tshwm sim muaj rau lub sijhawm no. Lawv qhov tshwm sim tsis cuam tshuam qhov tshwm sim ntawm Atorvastatin, yog li cov neeg mob zoo li no tau tso cai siv tshuaj txawm tias tsis muaj tshuaj kho.

Ib qho tseem ceeb heev yog kev siv txoj kev tswj kom tsis pub muaj txiaj ntsig hauv kev kho mob ntawm poj niam ntawm kev yug menyuam nrog lub cuab yeej no. Thaum lub sijhawm tswj hwm ntawm Torvacard, qhov pib ntawm kev xeeb tub yog qhov tsis tuaj yeem.

Phiv thiab haus tshaj

Thaum siv Torvacard, cov kev mob tshwm sim hauv qab no tej zaum yuav tshwm sim:

• mob taub hau
• insomnia
• Kev ntxhov siab thaum sawv ntxov
• xeev siab
• muaj kev ntxhov siab hauv kev ua haujlwm ntawm txoj hnyuv,
• pancreatitis
• tsis qab los
• leeg thiab leeg mob
• cramps
• anaphylactic kev poob siab,
• khaus
• daim tawv nqaij ua pob,
• kev sib daj sib deev.

Yog tias cov kev ua txhaum no thiab lwm yam kev ua txhaum raug txheeb xyuas, koj yuav tsum sab laj nrog koj tus kws kho mob thiab piav qhia qhov teeb meem Kev ywj pheej ywj pheej kom tshem tawm nws tuaj yeem ua rau muaj kev nyuaj.

Kev overdose nrog kev siv tshuaj kom yog qhov tsis zoo. Thaum nws tshwm sim, kev kho mob yam ntxwv qhia tau.

Kev cuam tshuam nrog lwm yam tshuaj

Txhawm rau zam lub cev tsis zoo, nws yog qhov yuav tsum tau coj mus rau hauv tus peculiarities ntawm kev ua ntawm lwm cov tshuaj noj rau cov hauj lwm zoo ntawm Torvacard.

Ceev faj yog xav tau thaum siv nws ua ke nrog:

• Erythromycin
• nrog antimycotic cov neeg sawv cev
• fibrates
• Cyclosporine
• nicotinic acid.

Cov tshuaj no muaj peev xwm nce lub siab ntawm atorvastatin hauv cov ntshav, vim tias qhov ntawd muaj kev pheej hmoo ntawm kev phiv.

Nws tseem yuav tsum tau ua tib zoo saib xyuas kev nce qib ntawm kev kho mob yog tias cov tshuaj xws li tau ntxiv rau Torvacard:

• Colestipol,
• Cimetidine
• Ketoconazole,
• tshuaj tiv thaiv qhov ncauj
• Digoxin.

Txhawm rau txhim kho txoj cai kho mob kom zoo, tus kws kho mob yuav tsum paub txog txhua yam tshuaj uas tus neeg mob tau noj. Qhov no yuav tso cai nws soj ntsuam cov duab.

Ntawm cov tshuaj uas tsim nyog los hloov cov tshuaj hauv cov lus nug txhais tau tias tuaj yeem hu ua:

Lawv siv yuav tsum pom zoo nrog kws kho mob. Yog li, yog tias yuav tsum xaiv cov tshuaj pheej yig ntawm cov tshuaj no, koj yuav tsum hu rau tus kws tshaj lij.

Tus neeg mob lub tswv yim

Kev tshuaj xyuas txog cov tshuaj Torvakard yog qhov tsis sib haum xeeb - ntau tus tuaj nrog tshuaj, tab sis ntau tus neeg mob tau yuam kom tsis kam noj tshuaj vim tias muaj kev phiv, uas ib zaug ntxiv tau lees tias yuav tsum tau sab laj nrog tus kws kho mob thiab soj ntsuam kev siv.

Kuv tau siv Torvacard tau ntau xyoo. Qhov ntsuas ntawm cov cholesterol yog txo qis los ntawm ib nrab, kev phiv tsis tshwm sim. Tus kws kho mob tau hais tias sim ua lwm txoj kev kho ntxiv, tab sis kuv tsis kam.

Kuv muaj ntau qhov phiv los ntawm Torvacard. Mob taub hau tsis xwm yeem, xeev siab, cramps thaum hmo ntuj. Nws tau raug kev txom nyem rau ob lub lis piam, tom qab ntawd nug tus kws kho mob kom hloov cov tshuaj no nrog lwm yam.

Kuv tsis nyiam cov tshuaj no. Thaum xub thawj txhua yam yog nyob rau hauv kev txiav txim, thiab tom qab ib hlis lub siab pib dhia, insomnia thiab mob taub hau heev tshwm sim. Tus kws kho mob tau hais tias cov kev sim tau dhau los ua qhov zoo dua, tab sis kuv tus kheej tau xav tsis zoo heev. Kuv yuav tsum tau tsis kam lees.

Kuv tau siv Torvard tau rau lub hlis tam sim no thiab kuv txaus siab heev. Cholesterol yog qhov qub, qab zib tau qis me ntsis, lub siab tau rov qab zoo li qub. Kuv tsis pom tias muaj kev mob tshwm sim.

Tus nqi ntawm Torvacard nws txawv nyob ntawm qhov ntau npaum ntawm Atorvastatin. Rau 30 ntsiav tshuaj ntawm 10 mg, koj yuav tsum them 250-330 rubles. Txhawm rau yuav ib pob khoom ntawm 90 ntsiav tshuaj (20 mg) yuav xav tau 950-1100 rubles. Cov ntsiav tshuaj nrog cov ntsiab lus siab tshaj plaws ntawm cov tshuaj nquag (40 mg) raug nqi 1270-1400 rubles. Cov pob no muaj 90 pcs.

Atherosclerosis yog dab tsi thiab dab tsi yog nws txaus ntshai?

Atherosclerosis yog ib qho kab mob nyob rau hauv cov hlab ntshav tshwm sim los ntawm kev tsim cov roj hauv plaques nyob rau sab hauv ntawm cov hlab ntsha tseem ceeb, uas ua rau txoj kev txhim kho ntawm cov kab mob loj heev uas ua rau tuag taus:

• Ntshav siab Performance index,
• Pathology ntawm lub plawv hloov tachycardia, arrhythmia thiab angina pectoris,
• Myocardial infarction thiab mob hlwb infarction,
• Hemorrhagic yam mob stroke,
• Atherosclerosis ntawm cov nqua coj mus rau kev ua tub rog nrog kev txiav tawm.

Cov teeb meem phom sij ua rau muaj kev nce ntxiv hauv tag nrho cov roj (cholesterol) hauv cov ntshav thiab cov lipoproteins tsawg cov roj (lipoproteins) ntawm LDL thiab VLDL.

Qhov qis qis qis dua cov tshuaj lipoproteins molecular tsawg thiab qhov siab dua cov lipoproteins molecular ceev hauv cov ntshav, txo qis kev pheej hmoo ntawm kev tsim kab mob atherosclerosis.

Cov statins ntawm pab pawg ntawm statins uas thaiv qhov kev txiav txim siab ntawm HMG-CoA reductase, uas ua ke cov mevalonic acid nyob rau hauv lub siab ua haujlwm, pab ua kom cov lipoprotein feem ua haujlwm tsawg, uas ua rau muaj kev sib txuas ntawm cov lipoproteins tsawg molecular phaus.

Tus sawv cev ntawm Torvacard pawg statins zoo rau txo cov roj (cholesterol) phem nrog cov kev ua:

• Mob ntshav qab zib mellitus
• Nrog rau cov hlab ntsha o,
• Nrog rau qhov kev pheej hmoo loj ntawm kev tsim mob plhaw plhaw.

Tus nquag ua hauj lwm hauv statin Torvacard yog atorvastatin, uas ua kom qis:

• Tag nrho cov ntsiab lus ntawm cov roj (cholesterol) hauv cov ntshav los ntawm 30.0% 46.0%,
• Qhov kev sib xyaw ntawm LDL lwg me me ntawm 40.0% 60.0%,
• Muaj qhov txo qis hauv cov ntsiab lus triglyceride.

Atherosclerosis

Cov muaj pes tsawg leeg ntawm cov tshuaj pab pawg ntawm statins Torvard

Torvacard yog tsim nyob rau hauv daim ntawv ntawm puag ncig thiab convex ntsiav tshuaj nyob rau hauv lub plhaub nrog lub ntsiab tshuaj atorvastatin hauv kev noj tshuaj ntawm 10.0 milligrams, 20.0 milligrams, 40.0 milligrams.

Ntxiv rau atorvastatin, Torvacard ntsiav tshuaj suav nrog:

• Microcrystalline cellulose lwg me me,
• Magnesium stearate thiab lawv oxide,
• Croscarmellose sodium lwg me me,
• Hypromellose thiab lactose,
• Silica ion
• Titanium ion dioxide,
• Tshuaj macrogol 6000.0,
• Talc.

Torvacard noj tshuaj thiab nws cov tshuaj noj hauv cov khw muag tshuaj tsuas yog muag los ntawm cov kws kho mob uas koom nrog.

Croscarmellose sodium

Daim foos tso tawm tshuaj Torvard

Torvacard statin ntsiav tshuaj muaj nyob hauv cov hlwv ntawm 10.0 pieces thiab ntim hauv cov thawv ntawv cardboard ntawm 3, lossis 9 blisters. Hauv txhua lub thawv, cov ntsiav tshuaj tsim cov lus qhia rau kev siv, tsis tas kawm uas koj tsis tuaj yeem pib noj Torvacard.

Tus nqi ntawm cov tshuaj hauv lub khw muag tshuaj network nyob ntawm qhov ntau npaum li cas ntawm cov tshuaj tivthaiv tseem ceeb ntawm atorvastatin thiab nyob ntawm cov naj npawb ntawm cov tshuaj hauv pob, thiab nyob ntawm lub teb chaws ntawm kev tsim khoom.

Cov Lavxias analogues yog cov pheej yig dua:

Hauv Lavxias, koj tuaj yeem yuav cov tshuaj analogues ntawm Torvacard pheej pheej yig los ntawm cov chaw tsim khoom hauv Lavxias, ua piv txwv, cov tshuaj Atorvastatin ntawm tus nqi nce mus txog 100.00 rubles Lavxias.

Qhov ntsuas mob no yog txoj kev siv nyiaj ntau tshaj plaws.

Cov Tshuaj Hauv Tshuaj

Torvacard yog ib qho tshuaj yeeb tshuaj statin uas tsom rau HMG-CoA reductase kom txwv qhov synthesis ntawm tag nrho cov roj (cholesterol). Cov ntshav muaj cov cholesterol nyob rau hauv txhua feem.

Torvacard, vim nws lub ntsiab lus tseem ceeb ntawm atorvastatin, txo qis qhov kev xav hauv cov ntshav:

• Cov roj (index) tag nrho,
• Tsawg heev lipoprotein lwg me me,
• Cov lipoproteins uas tsis tshua muaj ceeb thawj,
• Cov kua roj Triglyceride.

Qhov kev txiav txim ntawm statin Torvakard tshwm sim txawm nrog kev txhim kho ntawm cov caj ces xws li pathologies:

• Homozygous thiab heterozygous raws caj ces hypercholesterolemia,
• Thawj pathology ntawm hypercholesterolemia,
• Mixed pathology ntawm dyslipidemia.

Tsev neeg txog kab mob sib kis los teb tsis zoo rau kev kho mob nrog lwm cov tshuaj.

Torvacard muaj cov yam ntxwv ntawm kev ua haujlwm ntawm lub siab ua haujlwm kom nce cov synthesis ntawm lipoproteins siab molecular, uas txo txoj kev pheej hmoo ntawm kev txhim kho cov kab mob zoo li no hauv lub plawv thiab cov ntshav.:

• Tsis khov tsis khov uas lub ischemia ntawm lub plawv hloov khoom nruab nrog,
• Myocardial infarction
• Ischemic thiab hemorrhagic yam mob stroke,
• Thrombosis ntawm cov hlab ntsha tseem ceeb,
• Mob atherosclerosis.

Kev noj tshuaj txhua hnub Torvakard raug xaiv los ntawm tus kws kho mob tuaj koom nrog kev ntsuas thiab cov yam ntxwv ntawm tus neeg mob lub cev.

Kev noj tshuaj txhua hnub Torvacard raug xaiv los ntawm tus kws kho mob tuaj koom

Cov Tshuaj Pharmacokinetics

Lub pharmacokinetics ntawm cov tshuaj ntawm Torvacard pawg ntawm statins tsis yog nyob ntawm lub sijhawm ntawm kev noj cov ntsiav tshuaj thiab tsis khi rau noj mov:

• Cov txheej txheem kev nqus ntawm cov tshuaj los ntawm lub cev. Kev nqus tau tshwm sim hauv cov hnyuv thiab tom qab noj cov ntsiav tshuaj, qhov siab tshaj plaws nyob rau hauv cov ntshav hauv 1 2 teev. Qeb ntawm kev nqus tau nyob ntawm kev haus ntawm cov khoom nquag hauv Torvacard ntsiav tshuaj. Lub bioavailability ntawm cov tshuaj yog 14.0%, thiab cov nyhuv inhibitory ntawm reductase nce txog 30.0%. Yog tias cov tshuaj siv thaum yav tsaus ntuj, tom qab ntawd tag nrho cov roj (cholesterol) tag nrho raug txo los ntawm 30.0%, thiab lub sijhawm ntawm kev tswj hwm tsis nyob ntawm qhov ntsuas ntawm qhov txo qis nws cov roj molecular phaus feem,
• Kev faib tawm ntawm cov nquag tivthaiv ntawm atorvastatin hauv lub cev. Ntau tshaj 98.0% ntawm cov nquag sib xyaw ntawm atorvastatin khi rau cov protein.Kev tshawb txog cov tshuaj pom tias atorvastatin kis mus rau niam mis, uas txwv tsis pub noj Torvacard thaum tus poj niam pub mis rau menyuam,
• Tshuaj metabolism hauv. Kev tiv thaiv kab mob tshwm sim heev sib zog thiab cov khoom siv ua rau lub cev muaj ntau dua 70.0% ntawm cov nyhuv inhibitory ntawm reductase,
• Tshem cov tshuaj ntxuav pov tseg ntawm cov tshuaj sab nraud lub cev. Ib qho loj (txog 65.0%) ib feem ntawm cov nquag sib xyaw ntawm atorvastatin yog tawm sab nraud lub cev nrog cov kua tsib acid. Ib nrab-lub neej ntawm cov tshuaj rau 14 teev. Hauv cov zis, tsis pub ntau tshaj 2.0% ntawm atorvastatin raug kuaj pom. Tus so ntawm cov tshuaj yog tawm siv cov quav,
• Cov cwj pwm sib deev ntawm cov nyhuv ntawm Torvacard, nrog rau cov neeg mob lub hnub nyoog. Hauv cov neeg mob ntawm cov txiv neej laus, qhov feem pua ​​ntawm qhov qis LDL lwg me yog qhov ntau dua rau cov txiv neej uas muaj hnub nyoog yau dua. Hauv cov ntshav ntawm tus poj niam lub cev, qhov concentration ntawm cov tshuaj Torvard yog ntau dua, txawm hais tias qhov no tsis muaj feem cuam tshuam rau feem pua ​​txo hauv LDL feem. Torvacard tsis raug tso rau cov menyuam yaus hnub nyoog qis dua feem ntau,
• Pathology ntawm lub raum hloov khoom nruab nrog. Hloov khoom nruab nrog cev, lossis lwm qhov chaw raum tsis cuam tshuam qhov kev txiav txim ntawm atorvastatin hauv tus neeg mob cov ntshav, yog li ntawd, kev kho tshuaj txhua hnub tsis tas yuav ua. Atorvastatin khi cov khoom sib txuas rau cov protein ntau, uas tsis cuam tshuam los ntawm cov txheej txheem hemodialysis,
• Pathology ntawm lub siab ua hlwb. Yog tias cov kab mob siab hepatic cuam tshuam nrog kev haus cawv haus cawv, tom qab ntawd cov tshuaj tiv thaiv ntawm atorvastatin tau nce siab hauv cov ntshav.

Lub chaw muag tshuaj ntawm cov tshuaj ntawm Torvacard pawg ntawm cov statins tsis yog nyob ntawm lub sijhawm ntawm kev noj cov tshuaj

Kev cuam tshuam nrog lwm yam tshuaj

Cov ntaub ntawv qhia hauv feem pua ​​piv yog qhov sib txawv hauv cov ntaub ntawv hais txog kev siv Torvacard cais. AUC - thaj chaw hauv qab nkhaus qhia txog qib ntawm atorvastatin rau lub sijhawm twg. C max - cov ntsiab lus siab tshaj plaws ntawm cov khoom xyaw hauv cov ntshav.

Cov tshuaj sib xyaw ua ke ntawm Torvacard thiab cov tshuaj yeeb yaj kiab nrog cov tshuaj no tuaj yeem ua rau muaj kev pheej hmoo ntawm kev txhim kho cov leeg pob txha nqaij rhabdomyolysis:

• Cov tshuaj cyclosporin,
• Cov tshuaj yog styripentol,
• Ua ke cov statins nrog telithromycin thiab clarithromycin,
• Noj tshuaj Delavirdine,
• Ketocanazole thiab Voriconazole,
• Cov tshuaj Posaconazole thiab Itraconazole,
• HIV tiv thaiv kab mob inhibitors.

Cov tshuaj sib xyaw ua ke ntawm Torvacard thiab nws cov duab sib xyaw nrog cov tshuaj no tuaj yeem ua rau muaj kev pheej hmoo ntawm kev txhim kho cov leeg pob txha ntawm lub pob txha caj dab

Cov Tshuaj Kho Mob Torvacard thiab cov tshuaj pleev ib ce

Torvacard tshuaj thiab nws cov analogues yog tshuaj raws li kev tiv thaiv lwm yam:

• Hauv lub sijhawm tom qab lub sijhawm tsis pub dhau,
• Tom qab ischemic thiab hemorrhagic mob stroke,
• Tom qab tshem tawm ntawm thrombosis hauv pathology ntawm thrombosis.

Torvacard thiab nws cov analogues kuj tau sau tseg los tiv thaiv kev txhim kho ntawm atherosclerosis thiab lub plawv pathologies, hauv cov neeg mob uas muaj cov kev pheej hmoo txaus ntshai:

• Laus lub caij nyoog
• Cawv muaj yees
• Kev haus luam yeeb quav yeeb,
• Nrog rau cov hlab ntsha o.

Qhia cov tshuaj Torvakard, lossis nws cov analogues rau cov kab mob zoo li no hauv tib neeg lub cev:

• Lub siab ntawm apoliprotein B, nrog rau cov kev sib koom siab ntawm cov roj (cholesterol) tag nrho thiab nws cov roj ntsha qis, cov ntsiab lus ntawm triglycerides nyob rau hauv cov ntshav muaj pes tsawg leeg rau kev noj qab haus huv thiab theem nrab thaum siv ua ke nrog kev noj haus,
• Lub siab ntsuas ntawm triglyceride lwg me me ntawm hom 4 (Kev faib tawm Fredrickson), thaum lwm yam tshuaj tsis ua hauj lwm zoo,
• Nrog pathology, hom 3 dysbetalipoproteinemia (Fredrickson kev faib tawm),
• Nrog cov kab mob pathologies nrog kev pheej hmoo siab ntawm kev mob hlab ntsha hauv ischemia.

Cov Tshuaj Tiv Thaiv Torvacard lossis nws cov khoom sib txig

Tsis txhob sau tshuaj rau Torvacard noj tshuaj, nrog rau nws cov analogues hauv cov xwm txheej zoo li no:

• Siab siab ntawm lub cev mus rau hauv Cheebtsam hauv cov ntsiav tshuaj,
• Pathology ntawm lub siab ua haujlwm nrog kev ua haujlwm nce ntawm transminase lwg me me,
• Me-Pugh daim siab mob hlwb (qib A lossis B),
• Congenital pathologies ntawm lactose intolerance,
• Cov poj niam muaj menyuam hnub nyoog tsis muaj lub cev xeeb tub,
• Cov poj niam cev xeeb tub thiab cov niam laus saib xyuas,
• Loj hlob koj tus menyuam mus txog 18 xyoo.

Txoj kev siv statin Torvakard, lossis nws txoj kev sib txig sib xyaw ntawm cov tshuaj ib hnub thiab ib hnub twg

Lub sijhawm muaj txiaj ntsig zoo tshaj plaws rau kev noj cov tshuaj Torvacard, lossis nws cov analogues, yog ua ntej yuav mus pw, vim tias thaum hmo ntuj, cov ntsiab lus ntawm cov roj (cholesterol) yog qhov siab tshaj plaws.

Tag nrho cov chav kawm ntawm kev noj cov tshuaj nrog Torvacard analogues thiab cov tshuaj nws tus kheej yuav tsum nrog cov khoom noj muaj roj cholesterol.

Kev noj tshuaj txhua hnub ntawm cov ntsiav tshuaj thiab qhov tseeb ntawm lawv cov thawj coj:

• Thaum pib theem ntawm kev kho, qhov kev siv tshuaj txhua hnub ntawm 10.0 milligrams, lossis 20.0 milligrams, raug kho, nyob ntawm lipogram,
• Yog tias koj xav tau qis dua qhov ntsuas ntawm LDL lwg me me los ntawm 45.0% 50.0%, tom qab ntawd koj tuaj yeem pib kho nrog kev noj tshuaj 40.0 milligrams ib hnub twg. Yuav kom txo qis cov roj (cholesterol) sai, tus kws kho mob nws tus kheej tau txiav txim siab seb yuav siv cov tshuaj Torvacard, lossis Atorvastatin (Lavxias teb sab analogue),
• Qhov siab tshaj plaws tau tso cai noj tshuaj rau txhua hnub ntawm cov tshuaj no thiab nws cov tshuaj sib ntxiv yuav tsum tsis pub ntau dua 80.0 milligrams,
• Hloov cov tshuaj nrog nws cov tshuaj tiv thaiv kab mob tuaj yeem ua tiav tsis dhau 30 hnub tom qab pib kawm kho. Hloov pauv yog tsim yog tias cov tshuaj tsis qhia qhov tsim nyog kho tau, lossis tsis zoo cuam tshuam rau tus neeg mob lub cev. Nws yog ib qho tsim nyog los sab laj tus kws kho mob nrog cov mob tshwm sim, thiab nws yuav pom los ntawm cov analogues uas nws muaj kev nyab xeeb dua los hloov Torvacard,
• Tsis txhob siv Torvacard, lossis nws cov analogues li kev coj tus kheej,
• Thaum kho nrog statins, ib qho yuav tsum tsis txhob hnov ​​qab tias cov tshuaj ntawm pab pawg no thiab haus cawv tsis sib xws.

Kev siv Torvacard yog txwv tsis pub rau cov poj niam cev xeeb tub

Ntau tus ntxiv

Tshuaj, nyob rau hauv uas lub ntsiab feem yog atorvastatin, suav hais tias yog tshuaj analogues ntawm Torvacard. Tsis tas li, cov tshuaj tiv thaiv analogues ntawm cov tshuaj no tuaj yeem yog cov tshuaj noj, nyob hauv qhov uas ua kom sov yog rosuvastatin.

Cov analogues no cuam tshuam nrog cov kev ua tiav tshiab ntawm statins, qhov twg muaj tsawg dua qhov tshwm sim ntawm lub cev nrog kev siv tshuaj zoo.

Cov qauv ntsuas nrog cov tshuaj ua kom muaj zog atorvastatin:

• Statin Atoris,
• Lavxias analog ntawm Atorvastatin,
• Cov tshuaj Atomax
• Tshuaj Liprimar,
• Liptonorm ntsiav tshuaj,
• Tshuaj Tulip.

Cov tshuaj tiv thaiv uas muaj cov tshuaj rosuvastatin:

• Tshuaj Rosuvastatin,
• Noj Tshuaj Crestor,
• Rosucard ntsiav tshuaj,
• Tshuaj Roxer
• Cov tshuaj Rosulip.

Kev Sau ua ke, daim foos tso tawm

Atorvastatin - tsuas yog siv tshuaj ua haujlwm hauv Torvacard. Cov khoom siv ntxiv yog xav tau los muab cov ntsiav tshuaj ntau, nce nws lub neej txee, txhim kho kev zom zaub mov. Cov kev zam: magnesium oxide, cellulose, lactose monohydrate, croscarmellose sodium, hyprolose, silicon dioxide, magnesium stearate, plhaub (hypromellose, macrogol, titanium dioxide, talc).

Torvacard yog cov ntsiav tshuaj dawb-dawb, oval, muaj 10, 20, 40 mg ntawm cov tshuaj nquag. Cov pob khoom ntawm 30, 90 daim yog tsim.

Pharmacological kev txiav txim

Torvacard yog tus neeg saib xyuas kev tiv thaiv los ntawm pab pawg ntawm statins. Nws cov khoom xyaw nquag, atorvastatin, muaj lub peev xwm los thaiv cov haujlwm ntawm HMG-CoA reductase enzyme. Lub enzyme catalyzes ib qho ntawm cov thawj cov roj ntsha ua kom sib haum xeeb. Yog tsis muaj nws, txheej txheem ntawm kev tsim sterol nres. Ntshav roj yuav pib poob.

Kev sim kom them nyiaj rau kev ua kom tsis muaj menyuam yaus, lub cev tsoo "LDL" tsis zoo "uas muaj nws. Tib lub sij hawm, nws nce qhov khoom lag luam tsim "zoo" high-density lipoproteins (HDL), uas xav tau kom xa cov roj cholesterol mus rau hauv lub siab los ntawm cov ntaub so ntswg.

Noj cov tshuaj Torvacard tuaj yeem txo cov roj cholesterol los ntawm 30-46%, LDL - los ntawm 41-61%, triglycerides los ntawm 14-33%. Kev kho kom zoo ntawm cov lipid profile pab kom qeeb txoj kev loj hlob ntawm atherosclerosis. Nws ntseeg tau tias nce cov roj cholesterol LDL, nrog rau HDL tsawg, lub luag haujlwm tseem ceeb hauv nws txoj kev txhim kho.

Torvacard pab txo qis LDL hauv cov neeg mob uas muaj tsev neeg homozygous hypercholesterolemia. Tus txheej txheem no yog siv tshuaj ntau-ntau: qhov ntau dua koob, ntau qhov lawv cov concentration txo.

Atorvastatin nqus tau sai heev los ntawm lub cev. Hauv 1-2 teev tom qab kev tswj hwm, nws qib hauv cov ntshav nce mus txog qhov siab. Tom qab noj Torvacard, nws tseem nyob rau lwm 20-30 teev.

Cov tshuaj tau tso tawm los ntawm daim siab (98%), zoo li hauv lub raum (2%). Yog li, nws tuaj yeem raug kho rau cov neeg mob raum tsis ua haujlwm. Tab sis nrog teeb meem daim siab, nws yuav tsum ua nrog ceev faj.

Txo cov roj cholesterol, LDL tsis tau hais txog tam sim ntawd. Nws feem ntau yuav siv 2 lub lis piam kom ua tiav cov nyhuv thawj. Torvakard qhia pom qhov muaj zog tshaj plaws tom qab 4 lub lis piam los ntawm pib ntawm thawj coj.

Torvacard: kev taw qhia rau kev siv

Torvacard, zoo ib yam li ib qho statin, tau raug sau tseg rau cov neeg uas tsis tuaj yeem txhim kho cov roj cholesterol, LDL nrog zaub mov noj. Raws li cov lus qhia, Torvacard yog qhia rau:

• cov kab mob hom mob tib neeg- chaw mob ntshav siab, hterozygous hypercholesterolemia kom txo qis roj, LDL, apolipoprotein B, nce HDL,
• triglyceridemia,
• dysbetalipoproteinemia.

Hauv qee qhov tshwj xeeb, Torvacard raug xaj rau cov menyuam yaus hnub nyoog 10-17 xyoo, hauv leej twg, tom qab ib txoj kev qhia txog kev noj zaub mov, cov roj cholesterol tsis poob qis dua 190 mg / dl lossis LDL qis dua 160 mg / dl. Qhov taw qhia thib ob yuav tsum cuam tshuam nrog kev tiv thaiv kab mob kev tsis haum xeeb rau kev txhim kho cov kab mob plawv lossis muaj ≥ 2 qhov kev pheej hmoo rau lawv txoj kev loj hlob.

Atorvastatin tau sau tseg rau kev tiv thaiv kab mob ntawm cov kab mob plawv. Nrog rau daim ntawv asymptomatic ntawm cov kab mob plawv, cov neeg uas muaj ntau yam pheej hmoo rau nws txoj kev loj hlob (haus luam yeeb, cawv, ntshav siab, qis HDL, roj ntsha tsis sib haum), kev teem sijhawm ntawm atorvastatin pab tau:

• txo txoj kev pheej hmoo ntawm kev tsim mob stroke, lub plawv nres,
• tiv thaiv angina tawm tsam,
• Zam kev phais kom rov zoo ntshav li qub.

Cov neeg mob ntshav qab zib uas muaj qhov pheej hmoo txhim kho cov hlab plawv, cov tshuaj tau txhaj tshuaj kom txo qis kev pheej hmoo ntawm kev txhim kho mob hlab ntsha tawg, plawv nres.

Cov neeg mob plawv mob ntsig txog lub plawv txhawm rau siv Torvacard rau:

• txo cov kev pheej hmoo ntawm myocardial infarction, mob stroke (nrog / tsis tuag),
• txo tus naj npawb ntawm tsev kho mob rau mob plawv tsis ua haujlwm,
• tiv thaiv ntawm angina pectoris.

Txoj kev ntawm daim ntawv thov, ntau npaum li cas

Torvacard noj ib zaug / hnub, ua ntej, tom qab, lossis nrog zaub mov. Nws yog ib qho tseem ceeb kom ua raws tib lub sijhawm ntawm kev txais neeg kawm. Cov ntsiav tshuaj tau nqos tag nrho (tsis txhob zom, tsis txhob faib), ntxuav nrog ob peb sips dej.

Kev kho mob Torvacard pib nrog kev noj tshuaj tsawg kawg. Tom qab 4 lub lis piam, kws kho mob txheeb xyuas txog qib roj, LDL. Yog tias qhov txiaj ntsig xav tau tsis tiav, cov koob tshuaj tau nce ntxiv. Nyob rau hauv lub neej tom ntej, kev hloov kho koob tshuaj yog tau ua tiav nrog ntu nrog tsawg kawg 4 lub lis piam. Qhov tshuaj ntau ntau ntawm Torvacard yog 80 mg. Yog tias qhov tshuaj ntau npaum li no ntawm atorvastatin tsis muaj peev xwm kho cov roj cholesterol, cov tshuaj muaj zog ntau dua los yog tshuaj ntxiv nrog cov txiaj ntsig zoo ib yam li raug txiav txim.

Cov tshuaj pom zoo thaum pib ntawm Torvacard rau kev kho mob ntawm cov neeg mob muaj mob hypercholesterolemia, kev sib xyaw dyslipidemia yog 10-20 mg / hnub. Cov neeg mob uas xav tau kev txo qis sai cov roj (ntau dua 45%) yog cov siv 40 mg tam sim ntawd.

Cov kev kho mob zoo ib yam yog ua raws thaum sau tshuaj atorvastatin rau cov neeg mob ua mob rau cov hlab ntshav ntawm lub cev. Cov lus qhia rau Torvacard yog cov lus pom zoo los ntawm European Society rau Atherosclerosis rau cov hom phiaj ntawm kev kho lipid-txo qis. Nws ntseeg tias qhov ntsuas rau kev ua tiav yog qhov ua tiav ntawm cov roj (cholesterol) tag nrho

Raws li cov lus qhia rau kev siv Torvacard, cov tshuaj yuav tsum tsis txhob raug rau cov neeg mob rhiab ntawm atorvastatin, lwm yam tshuaj ntawm cov tshuaj lossis statins. Cov neeg mob uas tsis muaj mob lactose yuav tsum them sai sai rau qhov muaj cov lactose.

• nrog mob hepatic pathologies,
• nrog kev pheej tsis tu ncua hauv kev hloov pauv ntawm cov tsis paub keeb kwm,
• cov menyuam menyuam yaus (tshwj tsis yog rau cov menyuam yaus muaj kabmob heterozygous hypercholesterolemia),
• xeeb tub
• mis txiag
• Cov poj niam muaj hnub nyoog yug uas tsis siv tshuaj tiv thaiv kev cia siab.

Yog tias tus poj niam cev xeeb tub thaum noj Torvacard, cov tshuaj tam sim ntawd raug muab tso tseg. Cholesterol yog qhov tsim nyog rau tus me nyuam hauv plab kom nquag hloov kho. Cov kev sim ntawm nas tau pom tias cov tsiaj tau txais atorvastatin yug me nyuam mob cubs. Cov ntaub ntawv no zoo li rau cov kws tshwj xeeb tau txaus los txwv tsis pub siv cov statins ntawm cov poj niam cev xeeb tub

Cov neeg mob feem ntau zam cov tshuaj kom zoo. Cov kev mob tshwm sim tsis cuam tshuam rau lub neej zoo, dhau ob peb hnub lossis vas thiv. Qee pawg ntawm tib neeg zam cov kev kho mob nyuaj dua. Cov neeg mob ib leeg yuav ntsib kab mob loj. Cov teeb meem tshwm sim los ntawm Torvacard:

• mob ruas, mob caj pas,
• kev fab tshuaj tsis haum
• siab qab zib
• mob taub hau
• taub ntswg
• ua txhaum txoj kev zom zaub mov (cem quav, roj av, xeev siab, dyspepsia, raws plab),
• sib koom tes, mob leeg,
• mob leeg
• nce ALT, AST, GGT.

• qab zib tsawg
• huab hwm coj nce
• kev tsis nco qab
• insomnia
• npau suav phem
• kiv taub hau
• rhiab siab tsis xis nyob
• saj perversion
• amnesia
• qhov muag plooj
• tinnitus
• leeg tsis muaj zog
• caj dab mob
• o tuaj
• nkees
• npaws
• urticaria, khaus, tawm pob,
• leukocyturia,
• nce glycosylated hemoglobin.

• thrombocytopenia
• tshuaj mob hlwb
• pom kev pom
• cholestasis
• Quincke's edema,
• cov tshuaj tiv thaiv tsis zoo,
• mob hlwb
• mob o
• rhabdomyolysis,
• lub siab mos siab muag
• ua txhaum ntawm erection.

• anaphylaxis,
• lag ntseg
• daim siab ua hauj lwm
• gynecomastia
• interstitial mob ntsws.

Torvacard yog qhov tsim nyog nrog ceev faj rau cov neeg uas muaj lub siab nyiam rhabdomyolysis. Ua ntej pib kev kho mob, nrog rau thoob plaws hauv chav kawm, lawv yuav tsum tswj hwm theem ntawm creatine kinase. Cov neeg mob nrog:

• lub raum tsis ua hauj lwm zoo,
• cov thyroid deficiency (hypothyroidism),
• teeb meem muaj keeb muaj pob txha pob txha (nrog rau cov txheeb ze),
• myopathy / rhabdomyolysis tom qab noj keeb kwm ntawm statins,
• mob rau daim siab hnyav thiab / lossis kev quav dej caw.

Kev ceev faj tib yam yuav tsum tau ua raws rau cov neeg laus dua (laus dua 70), suav nrog lwm yam kev pheej hmoo.

Koj yuav tsum tau txwv tsis pub siv Torvacard, qhia koj tus kws kho mob yog tias koj muaj:

• txwv tsis pub cramps
• muaj ntshav siab / qis cov ntshav ntau ntau,
• lub siab poob zuj zus
• loj kis kab mob
• nyob rau hauv cov ntaub ntawv ntawm kev phais mob lossis thaum muaj xwm ceev.

Xaus

Kev siv tshuaj ntawm Torvakard pab pawg ntawm statins yog cov tshuaj muaj txiaj ntsig zoo nyob rau hauv kev sib tua tiv thaiv cov roj uas tsis tsim nyog thiab muaj kev phom sij, uas muaj cov kab mob loj dua ntawm cov tshuaj tiv thaiv kab mob, uas tso cai rau ib chav kawm tshuaj.

Cov nyhuv ntawm statins tsub kom cov zaub mov noj muaj roj. Tsis txhob siv Torvacard thiab analogues rau kev coj tus kheej ntawm koj tus kheej thiab koj tsev neeg.

Veronika, 35 xyoo: Kuv muaj hypercholesterolemia, thiab nws pom tias nws muaj tsev neeg ua. Kuv yuav tsum tau txo cov roj (cholesterol) nrog ntau yam tshuaj, tab sis tseem tus kws kho mob tau nres ntawm Torvakard ntsiav tshuaj.

Kuv tau noj lawv rau cov hlis ntawd, tab sis cov nyhuv thawj zaug kuv coj tom qab noj cov ntsiav tshuaj ib hlis tom qab. Thaum lub hlis no, kuv cov roj (cholesterol) tsis nce. Torvacard tsis muaj kev cuam tshuam zoo rau kuv lub cev.

Svyatoslav, 46 xyoo: Kuv raug kuaj mob atherosclerosis sai li sai tau thaum kuv muaj 40, thiab txij thaum ntawd los kuv tau tau niaj hnub kawm cov kev kho mob statin. Feem ntau, kev kho mob lub hom phiaj kav 10 12 lub hlis, tab sis nws cov nyhuv kav tsis ntev tshaj rau lub hlis, tom qab ntawd cov roj cholesterol yoov dua.

Ib xyoos thiab ib nrab dhau los, tus kws kho mob tau khaws tshuaj Torvakard rau kuv. Kuv tau noj nws rau 5 lub hlis, tab sis kuv xav tias qhov zoo ntawm cov tshuaj no tom qab ib hlis. Hauv lub sijhawm xyoo, kuv cov roj khov kho tau zoo li qub, tam sim no nws tau pib nce me ntsis, tab sis tsis muaj lub duav ceev.