Atorvastatin C3

• Stabilizes qib qab zib kom ntev
• Rov kho cov tshuaj insulin pancreatic

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Qhov teeb meem ntawm cov ntshav siab hauv cov ntshav hnub no tau ntsib ntau yam. Tus kws kho mob thiab kws kho plawv tau soj ntsuam qhov ntsuas no nrog kev saib xyuas tshwj xeeb, vim nws hais txog kev mob hauv cov hlab ntsha nyob, lawv kev sib tw, thiab lawv muaj peev xwm sib cog lus.

Txo cov qib roj cholesterol nrog tshuaj. Feem ntau, Atorvastatin ua tau zoo ntawm qhov no. Koj yuav tsum tau noj nws tsuas yog tom qab sab laj tus kws kho mob thiab dhau kev kuaj mob uas tsim nyog, uas yuav paub meej tias muaj cov ntsuas thiab cia koj xaiv ib qho zuj zus.

Cov tshuaj no rau cov chav kawm pharmacological ntawm statins, uas pab nres kev txhim kho ntawm cov plahaum roj ntshav ntawm phab ntsa ntawm cov hlab ntsha. Tib lub sijhawm, thaj chaw ntawm thaj chaw cuam tshuam ntawm cov hlab ntsha tom qab kev kho mob tseem zoo li qub. Cov tshuaj uas muaj hauv cov tshuaj muaj peev xwm ua rau qeeb ntawm kev muaj mob ntawm cov ntshav plawv, mob tsis txaus ntawm ob txhais ceg thiab cov kab mob cerebrovascular.

Atorvastatin yog qhov nqus tau zoo heev, tab sis cov zaub mov tuaj yeem cuam tshuam me ntsis ntawm qhov ntsuas no, txawm hais tias qhov txo qis hauv LDL cov ntsiab lus hauv cov ntshav tsis hloov.

Dab tsi yog ib feem ntawm cov tshuaj no? Calcium trihydrate yog ib qho tshuaj ua haujlwm ntawm cov tshuaj, thiab cov tshuaj ntxiv muaj xws li:

1. cellulose
2. calcium carbonate
3. silica
4. titanium
5. macrogol.

Cov tshuaj tuaj yeem muas hauv qhov ntau npaum li 10, 20, 40 thiab 80 milligrams.

Txhawm rau kom pom cov txiaj ntsig ntawm kev siv, koj yuav tsum noj cov ntsiav tshuaj tsis tu ncua ob lub lis piam yam tsis muaj qhov ua kom dhau. Tom qab ib hlis, qhov muaj txiaj ntsig zoo tshaj plaws ntawm kev txais tos tshwm sim, uas yuav khaws cia hauv tib theem lub sijhawm tag nrho kev kho.

Cov lus qhia rau kev siv tshuaj

Cov hau kev rau kev kho mob ntawm atherosclerosis thiab ntshav siab cov roj (cholesterol) yuav tsum muaj txhij txhua. Yog li no, atorvastatin pom zoo kom noj ib txhij nrog kev soj ntsuam ntawm kev noj tshuaj tiv thaiv kab mob, uas yuav tsum tau nyob ntev ntawm kev kho kom zoo.

Koj tuaj yeem noj tshuaj yam tsis tas yuav hais txog kev noj zaub mov, uas yog, txhua lub sijhawm yooj yim rau ib tus neeg. Qhov ntau npaum li cas yog muab rau ntawm ib leeg zuj zus los ntawm tus kws kho mob mus koom rau hauv lub hauv paus ntawm kev tshuaj ntsuam. Thoob plaws hauv chav kawm, cov qib roj cholesterol yuav tsum tau saib xyuas, thiab, raws li qhov no, yog tias tsim nyog, kho cov koob tshuaj thiab lub sijhawm kho tom qab ob mus rau plaub lub lis piam.

Kev kho mob pib nrog 10 milligrams ntawm cov tshuaj, nws yuav tsum noj ib hnub ib zaug. Tom qab ntawd tus nqi ntawm cov tshuaj tuaj yeem sib txawv ntawm 10-80 milligrams ib hnub. Yog tias cov tshuaj tau sau ua ke nrog Cyclosporine, ces tus nqi ntawm Atorvastatin yuav tsum tsis pub ntau dua 10 milligrams.

Yog tias noj tshuaj muaj feem xyuam nrog kev txhim kho ntawm kev txheeb ze lossis homozygous hypercholesterolemia, ces kev noj tshuaj yuav tsum muaj li 80 mg rau ib hnub. Tus nqi no yuav tsum tau muab faib ua plaub daim ntawv thov ntawm 20 milligrams txhua. Cov neeg mob lub raum tsis ua haujlwm tsis tas yuav kho cov tshuaj ntau npaum li cas, tsis zoo li cov neeg mob siab tsis ua haujlwm.

Yog tias kev noj tshuaj ntau dhau lossis haus tshuaj tsis haum tshwm sim, koj yuav tsum mus ntsib kws kho mob sai li sai tau txhawm rau kho cov tsos mob.

Kev taw qhia thiab contraindications rau siv

Thaum sau daim ntawv tshuaj noj, qhov muaj qhov tuaj yeem tiv thaiv kab mob rau kev siv yeeb tshuaj yuav tsum ua tib zoo xav.

Kev tswj hwm tus kheej ntawm cov tshuaj yog nruj me ntsis txwv tsis pub.

Lub sijhawm ua haujlwm yuav tsum yog tus kws kho mob tau koom nrog, coj mus rau hauv tus account muaj peev xwm ua tau contraindications thiab cov yam ntxwv ntawm tus neeg mob lub cev.

Vim li cas Atorvastatin feem ntau hais tseg?

Cov tshuaj no tau qhia:

• Nrog cov roj (cholesterol) siab.
• Nrog pathologies ntawm cov hlab ntsha thiab lub plawv (txawm tias cov kab mob no tsis tau tshawb pom, tab sis muaj kev pheej hmoo txaus ntshai xws li kev rog dhau, ntshav qab zib, hnub nyoog muaj hnub nyoog, kub siab, thiab mob riav).
• Tom qab tus neeg mob tau mob hlab ntsha tawg, mob plawv, thiab kuaj pom tus mob angina pectoris.

Raws li tau hais ua ntej, kev kho mob nrog Atorvastatin yuav tsum muab sib xyaw nrog kev noj haus.

Zoo li lwm yam tshuaj, cov tshuaj no muaj qee qhov contraindications rau siv.

Xws li cov khoom siv sib kis yog:

1. lub raum tsis ua hauj lwm
2. nquag ua daim siab mob
3. cev xeeb tub thiab lub sijhawm lactation,
4. hnub nyoog rau kaum yim,
5. intolerance rau cov tshuaj ntawm cov tshuaj, hauv kev sib txuas nrog uas ua xua tuaj yeem tshwm sim.

Atorvastatin yuav tsum tsis txhob coj los ntawm cov menyuam yaus, nrog rau cov hluas thaum muaj hnub nyoog qis dua, vim qhov tseeb tias kev nyab xeeb ntawm kev siv thiab qhov zoo ntawm kev kho mob nrog cov tshuaj no hauv cov menyuam hnub nyoog tseem tsis tau txhim kho.

Nws kuj tsis paub meej tias cov tshuaj tuaj yeem ua kom tshem tawm hauv niam mis. Txawm li cas los xij, coj mus rau hauv tus account qhov ntxim nyiam ntawm kev tshwm sim tsis zoo hauv cov menyuam mos, thaum qhia txog kev siv tshuaj rau cov poj niam thaum pub mis, nws yog ib qho tsim nyog kom tsis txhob pub mis niam.

Raws li rau cov poj niam uas tau kho kho thaum lawv lub hnub nyoog deev me nyuam, lawv yuav tsum siv cov kev tswj kom tsis muaj menyuam thaum lub sijhawm kho.

Feem ntau, kev teem sij hawm ntawm Atorvastatin ntawm lub hnub nyoog no tsuas yog tsim nyog thaum muaj qhov muaj feem yuav cev xeeb tub tsawg, thiab thaum tus poj niam paub txog qhov muaj feem yuav muaj kev pheej hmoo rau kev kho tus me nyuam hauv plab.

Phiv phiv ntawm kev siv tshuaj

Zoo li lwm yam tshuaj feem ntau, atorvastatin muaj ntau cov kev mob tshwm sim thaum nws siv tshuaj kho.

Qhov tshwm sim ntawm cov kev mob tshwm sim yuav tsum muab xam thaum noj tshuaj.

Txhawm rau tiv thaiv qhov ua tsis zoo nyob rau hauv lub cev, cov tshuaj yuav tsum raug sau tseg los ntawm koj tus kws kho mob nkaus xwb.

Kev siv cov tshuaj Atorvastatin tuaj yeem ua rau mob tshwm sim:

• kub siab, xeev siab, tsam plab thiab tso quav tsis xis nyob,
• kev fab tshuaj tsis haum
• thrombocytopenia, ntshav liab,
• mob ntsws thiab mob ntsws,
• mob urogenital, ntxiv rau muaj o,
• nce tawm hws,
• do hau
• cov tsos ntawm kev hnov ​​qab ntau dua rau lub teeb,
• qhov muag qhuav, leeg ntshav ntswg,
• tinnitus, mob taub hau thiab kiv taub hau,
• insomnia
• seborrhea, eczema,
• tawm hws ntau dhau
• khaus thiab tawm pob rau ntawm daim tawv nqaij,
• poob qis libido rau cov poj niam, tsis hnov ​​mob ejaculation thiab impotence rau txiv neej,
• myalgia, mob caj dab, mob leeg.

Kev cuam tshuam nrog lwm yam tshuaj

Nws tsis pom zoo kom siv cov tshuaj ib txhij nrog:

1. Antifungal tshuaj.
2. Cov kab mob tua kab mob, cov tshuaj tua kab mob.
3. Cyclosporine.
4. Derivatives ntawm fibroic acid.

Nrog rau kev sib txuam ntawm cov tshuaj no, kev nce siab ntawm Atorvastatin thiab kev pheej hmoo ntawm myalgia yog qhov tsis txaus ntseeg.

Kev siv ntawm kev ncua kev kawm, uas sib xyaw nrog aluminium thiab magnesium, tuaj yeem pab txo qis cov tshuaj ntawm cov tshuaj. Tab sis lawv tsis cuam tshuam qhov feem pua ​​ntawm cov txo cov roj (cholesterol) thiab LDL tag.

Nrog rau kev ceev faj, ib qho yuav tsum kho kev sib xyaw ntawm Atorvastatin nrog cov tshuaj uas txo cov tshuaj hormones steroid (piv txwv li, Ketoconazole lossis Spironolactone).

Cov lus qhia ntxiv rau siv

Ua ntej noj tshuaj Atorvastatin, nws raug nquahu kom koj ua tiav cov qib roj cholesterol los ntawm kev hloov koj txoj kev ua neej thiab kho koj li kev noj haus. Cov no yog qhov sib txawv ntawm kev tiv thaiv thiab kho cov hlab ntshav thiab lwm yam kab mob ntawm cov plab hnyuv siab raum.

Thaum noj tshuaj, myopathies yuav tshwm sim - qhov tsis muaj zog thiab mob hauv cov leeg ntawm lub cev. Yog tias muaj kev txhawj xeeb txog tus kab mob no, kev siv tshuaj yuav tsum nres tam sim ntawd. Ntxiv rau, qhov kev pheej hmoo ntawm kev txhim kho cov kab mob no yuav nce ntxiv nrog kev siv Atorvastatin nrog Erythromycin, Cyclosporine, tshuaj tua kab mob thiab nicotinic acid nrog tib lub sijhawm.

Thaum noj cov tshuaj, koj yuav tsum ua tib zoo saib thaum ua cov haujlwm uas xav tau qhov kev mloog ntxiv, zoo li thaum tsav tsheb.

Nws kuj tseem tsis pom zoo kom noj cov tshuaj statins thiab dej cawv, vim tias qhov no tuaj yeem hloov qhov cuam tshuam ntawm kev noj tshuaj lossis ua rau muaj kev cuam tshuam tshwm sim.

Cov tshuaj ntawm cov khoom kho mob

Cov tshuaj uas muaj cov tshuaj uas zoo ib yam thiab muaj cov nyhuv hauv lub cev, thiab tuaj yeem tsim kho kom tsis txhob siv Atorvastatin (analogues), suav nrog Atoris, Tulip, Lipoford, Ator, Torvakard, Lipramar, Rosulip thiab Liptonorm.

Lawv sib txawv li cas? Yog tias koj ua qhov kev sib piv, koj tuaj yeem pom tias qhov sib txawv ntawm qhov sib txawv tsuas yog txwv los ntawm lub teb chaws ntawm kev tsim cov tshuaj thiab cov chaw tsim khoom. Txhua yam tshuaj muaj lub cev sib xws ntawm cov khoom sib txuas (qhov hu ua generics) muaj cov npe sib txawv, uas ua rau muaj peev xwm ua tau patent lawv. Txij li tsis muaj qhov sib txawv hauv cov khoom xyaw dhia, cov tshuaj no tuaj yeem suav tias yog cov sib txig sib luag rau Atorvastatin.

Thaum lub sijhawm kho mob, Atorvastatin yuav tsum muab cia rau hauv qhov chaw deb chaw rau menyuam yaus nkag mus, thiab qhov twg tsis muaj hnub poob. Nws yog ib qho tseem ceeb tias qhov kub siab tsis tshaj 25 degrees Celsius.

Tus nqi ntawm cov tshuaj yog tsim cov nyiaj ib lub zuj zus los ntawm txhua lub tuam txhab kws tshuaj. Tus nqi nruab nrab ntawm cov tshuaj hauv 30 tus nqi yog:

• ntsiav tshuaj nrog tshuaj ntau npaum 10 mg - 140-250 rubles,
• ntsiav tshuaj nrog qhov ntau npaum ntawm 20 mg - 220-390 rubles,
• ntsiav tshuaj nrog qhov ntau npaum ntawm 40 mg - 170-610 rubles.

Tus nqi ntawm cov tshuaj kuj ntau nyob ntawm thaj av ntawm kev muag.

Raws li cov neeg mob uas tau siv cov tshuaj no, nws muaj cov txiaj ntsig zoo thiab ua rau muaj kev cuam tshuam ntawm cov roj khov hauv lub cev ceev ceev.

Atorvastatin tau piav qhia hauv video hauv kab lus no.

• Stabilizes qib qab zib kom ntev
• Rov kho cov tshuaj insulin pancreatic

Kev kho mob zoo li cas ntawm cov tshuaj

Atorvastatin S3 ntsiav tshuaj pab txo cov ntshav roj hauv cov ntshav. Thaum siv cov tshuaj, qhov tshwm sim ntawm tus neeg mob uas muaj cov kab mob hauv qab no ntawm cov hlab plawv tau raug txo:

Cov tshuaj txo cov kev pheej hmoo ntawm cov teeb meem ntawm atherosclerosis nyob ib puag ncig hauv qab no ua rau muaj kev cuam tshuam:

• hnub nyoog siab heev
• muaj cov nicotine yees,
• ntshav siab
• ntshav qab zib kom ntau.

Cov tshuaj Atorvastatin SZ pab txo cov ntshav viscosity. Nws txhim kho kev mob ntawm cov kab mob hematopoietic, tiv thaiv kev tawg ntawm atherosclerotic plaques.

Lub tswvyim ntawm kev siv yeeb tshuaj

Qhov pom zoo rau kev noj tshuaj txhua hnub txawv txav ntawm 10 txog 80 mg. Cov tshuaj yuav tsum haus ib zaug ib hnub.

Rau thawj hom hypercholesterolemia thiab sib xyaw ua ke hyperlipidemia, qhov tshuaj pom zoo txhua hnub yog 10 mg. Yog hais tias tus neeg mob tau homozygous tsev neeg hypercholesterolemia, thawj koob tshuaj yog xaiv ib tus zuj zus: nyob ntawm qhov mob hnyav ntawm cov tsos mob tseem ceeb ntawm tus kab mob.

Yog tias daim siab ua haujlwm tsis zoo, kev ceev faj yuav tsum ua kom zoo thaum siv tshuaj vim qhov ua kom qeeb ntawm nws txoj kev tshem tawm hauv lub cev. Nyob rau ntawm qhov muaj cov kab mob sib xws, nws yog qhov tsim nyog los tswj cov kev ua ntawm hepatic transaminases:

Nrog rau kev ua haujlwm ntau ntawm hepatic transaminases, txo qis hauv kev pom zoo txhua hnub cov tshuaj yog qhov tsim nyog.

Yog tias tus neeg mob tau mob raum, tsis tas yuav hloov cov tshuaj. Cov neeg laus yuav tsum noj cov tshuaj raws li tus qauv (tsis muaj kev kho los ntawm kev siv tshuaj txhua hnub).

Cov Yuav Tsum Tau Ua

Raws li cov lus qhia rau kev siv, nws raug nquahu kom tso tseg kev siv tshuaj thaum lub sijhawm xav tias yuav muaj menyuam thiab pub mis. Cov tshuaj yuav tsum tsis txhob quag cawv thaum lub sij hawm cev xeeb tub. Nws yog kis rau cov neeg mob hnub nyoog qis dua 18 xyoo. Cov tshuaj yuav tsum tsis txhob noj nrog hypersensitivity rau nws lub Cheebtsam. Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm lactose intolerance, qabzib-galactose malabsorption.

Cov tshuaj yog siv nrog ceev faj nyob rau hauv muaj cov nram qab no pathologies:

• leeg ntshav siab
• qaug dab peg
• mob ntshav qab zib mellitus
• pathologies ntawm cov leeg nqaij,
• ua txhaum ntawm cov dej-electrolyte tshuav.

Sab sij huam

Thaum siv tshuaj, cov kev mob tshwm sim los ntawm cov leeg poob siab tuaj yeem tshwm sim:

• mob taub hau
• kiv taub hau
• pw tsis taus
• qhov tshwm sim ntawm asthenic syndrome,
• paresthesia
• peripheral neuropathy.

Thaum siv tshuaj, cov kev mob tshwm sim hauv qab no tuaj yeem pom:

• tinnitus
• lub plawv dhia,
• ntshav siab
• arrhythmia,
• taub ntswg
• thrombocytopenia
• xeev siab
• flatulence
• mob hauv plab,
• tsis zoo nyob rau hauv saj xaav
• tsis deev tsav,
• cov tsos ntawm kev o nyob rau hauv cov pob qij txha,
• mob leeg
• daim siab ua hauj lwm
• plaub hau poob
• khaus tawv
• peripheral edema,
• mob hauv siab
• nkees
• daim ntaub thaiv ua ntej lub qhov muag
• nco qab tsis zoo
• muaj zog concentration ntawm glycosylated hemoglobin.

Cov yam ntxwv ntawm kev sib txuam nrog lwm cov tshuaj

Atorvastatin SZ tsis pom zoo kom siv ib txhij nrog Varvarin. Ib cov tshuaj tsim los txo cov roj hauv lub cev ua haujlwm tsis zoo nrog rau cov tshuaj hauv qab no:

• tshuaj pom zoo nrog cov nyhuv antifungal,
• tshuaj tua kab mob macrolide,
• txhais tau tias nrog cov nyhuv immunosuppressive.

Thaum siv cov tshuaj antacids tsim los ua kom tsis haum hydrochloric acid, cov ntshav plasma cov ntsiab lus ntawm kev ua haujlwm ntawm cov tshuaj yuav txo qis. Yog tias nws yuav tsum tau siv cov tshuaj no ib txhij nrog Atorvastatin SZ, qhov kev txiav txim siab nce cov tshuaj lipid-txo cov tshuaj yuav tsum yog tus kws kho mob siv.

Lub txee lub neej ntawm cov tshuaj yog peb xyoos. Cov tshuaj yuav tsum muab cia rau hauv qhov chaw tiv thaiv los ntawm tshav ntuj ncaj qha. Qhov kub zoo rau khaws cov tshuaj yog 25 degrees.

Txij li thaum cov tshuaj muaj cov cim qhia tau hypolipidemic, kev tshuaj xyuas txog nws txoj kev siv feem ntau muaj txiaj ntsig. Cov tshuaj feem ntau tau noj nrog kev nce hauv cov ntshav hauv cov ntshav siab, nrog los ntawm angina pectoris.

Tib lub sijhawm, daim ntawv teev cov kev mob tshwm sim thaum siv Atorvastatin SZ yog qhov siab heev. Qhov no yog vim qhov kev tsis zoo xyuas ntawm tus neeg mob.

Yuav txhim kho cov nyhuv li cas ntawm cov tshuaj?

Txhawm rau txhim kho txoj kev kho kom zoo ntawm cov tshuaj, nws pom zoo kom ua raws li kev noj haus nruj. Nws lub hom phiaj tseem ceeb yog txhawm rau txhim kho lipid metabolism.

Nrog rau kev nce qib hauv cov roj (cholesterol) hauv lub cev, koj yuav tsum tau txwv kev ua zaub mov uas muaj cov rog cov tsiaj. Cov khoom noj muaj cov tais diav uas saturate lub cev nrog fiber ntau.

Yog tias koj muaj cov roj (cholesterol) siab, koj yuav tsum noj cov zaub mov uas muaj phytosterols ntau. Cov no suav nrog:

• noob hnav noob,
• cov khoom muaj cov kab mob nplej,
• paj noob hlis noob
• flaxseeds
• txiv roj roj
• av daj
• txiv hmap noob roj.

Qhov kev noj haus yuav tsum muaj cov zaub mov uas muaj pectin ntxiv: cov txiv ntoo, cov txiv av txiv ntoo, cov txiv ntoo. Nrog rau cov ntshav siab cov rog, cov khoom lag luam hauv qab no kuj tseem siv tau:

• zaub ntsuab
• ntsuab zaub xas lav nplooj
• artichoke
• pauj niam
• dill
• zaub txhwb qaib.

Thaum siv cov tshuaj Atorvastatin SZ, nws raug nquahu kom tso tseg kev siv cov nqaij npuas, nqaij nqaij, nqaij ntsaj, haus nqaij, nqaij hnyuv ntxwm. Rog ntau yam ntawm ntses, liab caviar, cws, thiab ntses kaus poom tseem poob hauv qab qhov kev txwv.

Nws raug nquahu kom tsis suav cov zaub mov cov tais diav tau teev hauv cov npe:

• butter ci,
• mushroom si
• lee
• siab rog tsev cheese,
• qaub cream
• mis nyuj khov
• Chocolate khoom
• cov khoom siv roj
• mayonnaise
• ketchup.

Atorvastatin muaj cov yeeb yaj kiab (analogues). Tulip yog siv rau hauv kev kho mob los ntawm kev sib xyaw ua ke hyperlipidemia, thawj hypercholesterolemia.

Nws raug nquahu kom tso tseg txoj kev siv tshuaj nrog qhov mob siab rau nws lub Cheebtsam, lactose intolerance. Tulip txwv tsis pub siv thaum cev xeeb tub thiab pub niam mis. Cov tshuaj tsis raug tso cai raug txwv rau cov neeg mob hnub nyoog qis dua kaum yim.

Tulip yuav tsum tau siv nrog ceev faj nrog ntshav siab, sepsis, hluav taws xob tsis txaus.

Thaum noj tshuaj, cov kev mob tshwm sim txuas ntxiv tuaj yeem tshwm sim:

• asthenia
• mob taub hau
• muaj zog tiv thaiv tsis tau zoo
• cov tsos ntawm kev mob hauv pob qij txha,
• edema
• cov tsos ntawm daim tawv nqaij ua pob,
• tinnitus
• cov tsos ntawm hnyav dua
• tsawg potency
• qhov tshwm sim ntawm qaug dab peg,
• peripheral neuropathy,
• thrombocytopenia.

Kev noj tshuaj txhua hnub ntawm Tulip txawv ntawm 10 txog 80 mg. Feem ntau, tus neeg mob tau xaj 10-20 mg ntawm cov tshuaj ib hnub.

Lipitor kuj nyob nrog pab pawg ntawm statins. Cov tshuaj pab txo cov roj hauv cov neeg mob uas tau kuaj pom tias yog homozygous tsev neeg hypercholesterolemia.

Cov cim hauv qab no rau kev siv Lipitor paub qhov txawv:

• cev xeeb tub
• lub sij hawm pub niam mis,
• muaj lub cev tsis haum rau lub tshuaj,
• muaj cov mob siab hnyav pathologies.

Lipitor yog siv nrog ceev faj thaum muaj kev vam khom rau haus dej haus cawv, ntshav siab, thiab tsis txaus electrolyte. Thaum siv cov tshuaj, cov kev mob tshwm sim xws li xeev siab, tsis xis nyob hauv plab, qhov zoo li lub qhov ncauj qhuav, mob taub hau, tsaug zog, kiv taub hau, tuaj tsis ncav, thiab ntshav siab tau pom. Qee qhov xwm txheej, nrog kev siv Lipitor, cov teeb meem no tshwm sim:

• cov tsos ntawm cramps hauv cov leeg nqaij ntawm ob txhais ceg,
• qhov tshwm sim ntawm paum ntawm poj niam qhov chaw mos,
• lub plawv dhia
• qhuav conjunctiva
• nce tawm hws,
• qhov tshwm sim tshwm sim ntawm cov tsos mob ntawm ntsws los yog rhinitis.

Hauv kev xaus, nws yuav tsum raug sau tseg tias cov tshuaj siv nquag siv tsis yog rau kev tiv thaiv. Cov tshuaj txo qhov ntxim nyiam ntawm atherosclerosis nyob ib puag ncig muaj keeb tiv thaiv kab mob rau tus kab mob no.

Pharmacological kev txiav txim

Cov tshuaj muaj cov nyhuv inhibitory ntawm cov kev sib txuas ntawm cov tshuaj steroids thiab roj (cholesterol). Cov khoom nquag ua si muaj keeb kwm hluavtaws. Nws yog lub zog sib tw ntawm cov enzyme HMG-CoA reductase, uas yog lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm mevalonate - ib yam khoom uas tsim nyog rau kev tsim cov roj (cholesterol).

Cov cuab yeej tso cai rau koj kom txo qis roj, LDL, triglycerides nyob rau hauv cov neeg kev txom nyem los ntawm homo- lossis heterozygous tsev neeg hypercholesterolemia. Nws tseem tso cai rau koj nce qib ntawm cov lipoproteins uas muaj ntau, uas yog cov txiaj ntsig zoo rau lub cev.

Cov cuab yeej tso cai rau koj kom txo qis roj, LDL, triglycerides nyob rau hauv cov neeg kev txom nyem los ntawm heterozygous tsev neeg hypercholesterolemia.

Atorvastatin tsis tsuas yog inhibits qhov kev ua ub no ntawm enzyme koom nrog hauv kev sib txuas ntawm cov roj cholesterol, tab sis kuj tseem yuav pab tshem tawm qhov kev ua tom kawg. Qhov no yog ua tiav los ntawm nce ntau ntawm cov xov tooj ntawm tes uas khi rau cov lipoproteins uas tsis muaj ntau thiab muab lawv cov kev sib cais tshuaj ntxiv.

Atorvastatin ua rau muaj kev hloov pauv ntawm qhov sib piv ntawm cov lipoproteins siab thiab tsawg ntom nti los ntawm kev txwv cov khoom lag luam tom qab, lawv siv, nrog rau qhov kev hloov pauv tau zoo rau hauv cov khoom lawv tus kheej. Lub cuab yeej siv tau zoo nyob rau hauv cov xwm txheej uas thaum noj lwm cov tshuaj lipid-qis, qib ntawm LDL tsis txo qis.

Nyob hauv kev cuam tshuam ntawm atorvastatin, qhov kev nqus ntawm cov roj cholesterol hauv cov roj ntsha poob qis mus rau 50%, LDL txog 60%, apolipoprotein-B rau 50%, triglycerides txog 30%. Cov ntaub ntawv tau txais thaum lub sijhawm kuaj cov tshuaj yuav luag zoo sib xws hauv cov neeg raug mob los ntawm cov mob tsis muaj mob thiab tsis muaj ntshav ntawm hypercholesterolemia, sib xyaw hyperlipidemia thiab ntshav qab zib tsis muaj tshuaj insulin.

Nyob hauv kev cuam tshuam ntawm atorvastatin, rheological yam ntxwv ntawm cov ntshav tau txhim kho los ntawm kev txo nws cov viscosity. Txo qhov kev ua ub ua no ntawm kev ua kom cov plasmaets thiab qee qhov sib txuam ntawm cov coagulation system tau pom. Cov tshuaj cuam tshuam rau kev ua ntawm macrophages, tiv thaiv kev sib tawg ntawm atherosclerotic plaques, uas tuaj yeem tshwm sim nrog lawv koom tes.

Nyob hauv kev cuam tshuam ntawm atorvastatin, rheological yam ntxwv ntawm cov ntshav tau txhim kho los ntawm kev txo nws cov viscosity.

Lub cuab yeej tuaj yeem txo txoj kev pheej hmoo ntawm kev tuag vim cov ntaub so ntswg ischemia los ntawm 15% thaum noj ntau npaum 80 mg. Cov qib ntawm txo cov ntsiab lus ntawm cov qes lipoproteins tsawg ntawm cov roj ntsha yog nyob ntawm cov koob tshuaj noj.

Cov Tshuaj Pharmacokinetics

Cov tshuaj ua ke ntawm cov tshuaj thaum noj ntawm qhov ncauj yog nquag nqus los ntawm mucous daim nyias nyias ntawm lub plab zom mov. Qhov siab tshaj plaws kev ua tau zoo ntawm cov nquag ua haujlwm hauv plasma yog pom 60-120 feeb tom qab kev tswj hwm. Hauv cov neeg mob poj niam, cov ntsiab lus ntawm atorvastatin hauv cov hlab ntshav yog 1/5 siab dua txiv neej. Kev noj tshuaj ntau dua yog nqus tau ntau dua, cov ntshav plasma concentration nyob ntawm cov tshuaj noj kom tsawg.

Tag nrho bioavailability ntawm lub active tivthaiv yog 15%. Txog 30% ntawm cov koob tshuaj tau noj sib tw tiv thaiv HMG-CoA reductase. Qib ntawm bioavailability ntawm atorvastatin yog vim muaj kev hloov pauv hauv cov zom zaub mov uas cov tshuaj raug nyob rau hauv plab hnyuv mucosa thiab kab mob siab. Thaum noj cov zaub mov, ob qhov nrawm thiab qib ntawm kev nqus ntawm cov khoom nquag tau txo.

Thaum nws nkag mus rau hauv cov ntshav ntshav, cov tshuaj yuav luag txhua txoj hlua khi thauj peptides. Cov tshuaj yeeb qaug tshuaj hauv cov khoom me me nkag mus los ntawm cov kab mob ua kom cov ntshav liab.

Qib ntawm kev siv mentsis ntawm lub cev yog vim qhov hloov pauv hauv cov zaub mov uas nws raug nyob rau hauv plab hnyuv hnyuv.

Thaum lub zog hloov pauv ntawm atorvastatin, ob yam tshuaj yeeb tshuaj tau tsim. Cov kev ua ntawm metabolites yog sib piv nrog cov pib ntawm qhov pib. Txog li 70% ntawm cov nyhuv ntawm cov tshuaj yog muab vim yog cov kev ua ntawm cov metabolites.

Kev hloov tshuaj lom neeg ntawm atorvastatin nyob rau hauv kab mob hepatobiliary tshwm sim nyob rau hauv kev cuam tshuam ntawm CYP3A4 isoenzyme. Cov nquag ua haujlwm ntawm cov tshuaj rau qee qhov tsis haum nws cov kev ua.

Kev tshem tawm ntawm cov tshuaj tshwm sim feem ntau nrog ntws ntawm cov kua tsib. Ib nrab-lub neej yog me ntsis dhau 12 teev. Kev kho mob zoo ntawm atorvastatin kav li ib hnub.

Kev ntsuas rau siv

Kev qhia siv rau cov cuab yeej no yog:

• tsev neeg thiab tsis-tsev neeg hypercholesterolemia,
• tag nrho hyperlipidemia,
• cov kab mob cuam tshuam nrog kev tsis txaus ntseeg ntawm betalipoproteins,
• kab mob hypertriglyceridemia.

Atorvastatin tseem siv los ua yeeb tshuaj rau kev tiv thaiv kab mob ntawm cov hlab plawv. Nws kuj tseem siv los tiv thaiv cov teeb meem ntxiv hauv cov neeg mob plawv. Pab txo kev pheej hmoo ntawm kev tuag nyob hauv cov neeg mob ntawm pab pawg no.

Nrog saib xyuas

Kev xyuam xim tshwj xeeb thaum kho yuav tsum pom nyob hauv cov neeg mob siab tsis ua haujlwm. Cov txheeb ze tsis sib haum yog kev haus dej cawv, txij li kev haus dej cawv tuaj yeem ua rau qhov tshwm sim ntawm pathologies ntawm hepatobiliary huam.

Atorvastatin tsis pom zoo rau cov neeg uas muaj cov teeb meem no:

• kev tsis sib haum hauv qhov sib npaug ntawm electrolytes,
• hyperthyroidism
• metabolic ntshawv siab
• septicemia
• ntshav siab
• SD
• qaug dab peg
• kev phais kho tsis ntev los no.

Yuav noj li cas Atorvastatin C3

Cov tshuaj tau noj ntawm qhov ncauj, tsis hais lub sijhawm nruab hnub. Atorvastatin txoj kev kho yog ua tom qab sim ua rau tswj cov qib roj cholesterol uas yog siv cov khoom noj tshwj xeeb. Yog tias nws tsis muaj txiaj ntsig, ntxiv rau kev txwv khoom noj, tus neeg mob yuav tsum tau siv cov tshuaj no.

Atorvastatin C3 ntsiav tshuaj noj ib hnub ib zaug.

Thaum xaiv txoj kev txiav tshuaj ib leeg rau ib hnub, qhov mob hnyav npaum li cas los xam. Ntau li ntau tau, 80 mg ntawm cov tshuaj ib hnub tuaj yeem tsim kho. Cov ntsiav tshuaj noj ib zaug ib hnub.

Kev xaiv ntawm cov tshuaj uas yuav tsum tau muaj feem ntau pib nrog kev teem caij ntawm cov txheej txheem yam tsawg kawg nkaus ntawm 10 mg. Tom qab ntawd, txhua txhua ib nrab ntawm ib hlis lossis ib hlis, tus neeg mob yuav tsum ua ib qho kev soj ntsuam rau lub ntsiab lus ntawm lipids hauv cov hlab ntshav. Ua raws li cov txiaj ntsig ntawm kev kho mob, qhov tshuaj yuav ntau dua lossis nce nyob rau tib theem.

Lub plab zom mov

Yuav tuaj yeem kho cov kev kho mob uas muaj cov kev tsis zoo hauv qab no:

• lub plab zom mov
• tsam plab
• epigastric mob
• hyperactivation ntawm daim siab enzymes,
• dajntoo
• pancreatic o,
• xeev siab
• ntuav

Noj Atorvastatin C3 yuav ua rau tsam plab.

Los ntawm cov leeg musculoskeletal

• mob leeg
• mob tej pob txha
• cramps
• leeg leeg ruptures.

Atorvastatin C3 tuaj yeem ua rau mob nqaij pob txha.

• tshuaj tiv thaiv anaphylactic,
• tshuaj lom necrolysis.

Cov lus qhia tshwj xeeb

Thaum lub sij hawm kho nrog atorvastatin, pom cov nyhuv ntawm cov leeg pob txha raug mob. Qhov tseeb no yuav tsum tau saib xyuas ntawm theem ntawm creatine phosphokinase. Yog tias pom muaj myopathy tshwm sim, tsum tsis txhob siv cov tshuaj. Tus neeg mob yuav tsum tau sab laj nrog kws kho mob sai sai yog tias muaj mob ntawm cov leeg nqaij los yog cov leeg tsis muaj zog.

Cuam tshuam rau lub peev xwm los tswj cov tshuab

Thaum muaj kev phiv tshuaj los ntawm cov leeg hlwb, koj yuav tsum txwv lub sijhawm nyob tom qab lub log kom muaj kev nyab xeeb.

Yog tias muaj qhov tshwm sim tsis zoo los ntawm cov leeg poob siab tshwm sim, kev tswj hwm kev thauj khoom yuav tsum txwv.

Daim ntawv thov rau lub siab ua haujlwm tsis zoo

Kev kho mob ntawm cov neeg mob raum lub raum yuav tsum tau nqa nrog kev saib xyuas ntawm theem ntawm daim siab enzymes. Ua raws li qib ntawm lawv cov kev ua haujlwm, qhov ntau npaum ntawm cov tshuaj tau tswj hwm.

Lub raum tsis koom nrog hauv lub metabolism lossis qhov tawm ntawm cov tshuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Kev sib koom tes nrog phenazone tsis yog nrog los ntawm kev hloov pauv hauv cov khoom lag luam pharmacokinetic ntawm ob tus neeg sawv cev.

Kev siv ib txhij ntawm cov tshuaj antacids ua rau txo qis hauv cov ntsiab lus ntawm atorvastatin hauv cov hlab ntsha. Qhov no yog vim muaj qhov nqus tsis zoo ntawm cov tshuaj nquag.

Cov tshuaj uas ua rau kom muaj kev ua ntau ntawm CYP3A4 isoenzyme txo qis qhov kev xav ntawm cov tshuaj no hauv cov ntshav ntshav. Rifampicin muaj cov txiaj ntsig zoo rau lub plawv zawv plab hlaus, yog li ntawd, tsis cuam tshuam rau pharmacokinetics ntawm cov tshuaj.

Kev tswj hwm tib txhij ntawm Atorvastatin thiab Cyclosporine tuaj yeem ua rau muaj kev pheej hmoo ntawm cov leeg pathologies.

Kev siv yooj yim nrog digoxin hauv kev noj tshuaj tsawg tsis hloov pauv thaj chaw ntawm cov tshuaj. Ntawm qhov ntau tshaj txhua hnub ntau npaum li cas ntawm atorvastatin, nce 1/5 ntawm cov ntshav cov ntsiab lus plox Digoxin yog ua tau.

Cyclosporine yuav ua rau muaj kev pheej hmoo ntawm cov leeg tsis zoo.

Tsis muaj kev cuam tshuam tseem ceeb ntawm cov tshuaj nrog terfenadine tau sau tseg.

Cov kev hloov hauv qab no rau cov tshuaj no:

Atorvastatin C3 tshuaj xyuas

Gennady Ishchenko, kws kho plawv, Moscow

Atorvastatin yog cov tshuaj uas tso cai rau koj los tswj cov qib ntawm lipids hauv qee cov kab mob. Nws tau sau tseg ob qho tib si rau cov neeg uas muaj keeb kwm ntxiv hauv qhov kev mob siab nyob hauv lub plasma cov roj cholesterol thiab lwm yam rog, thiab rau cov neeg mob uas tau txais cov kab mob no.

Cov cuab yeej tso cai rau kev tiv thaiv cov mob plawv. Ua ke nrog kev noj zaub mov kom raug, cov neeg mob tuaj yeem tswj lub cev kom zoo thiab ua lub neej nyob sib luag yam tsis muaj kev txhawj xeeb txog cov teeb meem mob plawv.

Larisa Oleshchuk, kws kho mob, Ufa

Cov cuab yeej no muab rau cov neeg uas muaj tsev neeg endogenous hypercholesterolemia ib lub sijhawm rau lub neej zoo. Kuv sau ntawv tshuaj atorvastatin tsis yog rau lawv xwb, tab sis kuj rau lwm tus neeg mob uas muaj kev pheej hmoo siab ntawm atherosclerotic tso nyiaj thiab lawv cov kev xa mus ua pathologies.

Kuv tsis pom zoo kom yuav cov tshuaj ntawm lub tsev muag tshuaj ntawm koj tus kheej. Txoj kev kho yuav tsum yog txoj kev xaiv kom raug yog li niaj hnub noj thiab soj ntsuam ib ntus kom txog qib siab hepatic transaminases. Yog tias tsis ua raws li, txoj kev kho tuaj yeem ua rau muaj kev phiv loj heev.

Andrey, 48 xyoo, St. Petersburg

Kev kho mob zoo Ua ke nrog kev noj zaub mov tshwj xeeb, nws yuav pab tswj cov qib roj cholesterol kom tsis pub dhau. Kuv coj nws raws li kws kho mob hais, Kuv xeem dhau txhua qhov kev kuaj mob raws sijhawm. Txog tam sim no, tsis muaj kev tsis txaus siab tau tshwm sim. Yog tias koj ua txhua yam raws li sau hauv cov lus qhia rau kev siv, tom qab ntawv yuav tsis muaj teeb meem thaum kho. Tsis txhob saib xyuas tus kheej. Kev tshuaj xyuas tas li los ntawm kws kho mob yog tus yuam sij rau kev kho kom zoo.

Elizabeth, 55 xyoo, Perm

Kuv sim noj atorvastatin. Qhov kev kho mob kav ntev me ntsis dhau 2 lub lis piam. Tom qab ntawd nws pib pom tias tsis muaj zog hauv cov leeg, mob tau tshwm sim. Thaum xub thawj kuv tsis tau xa ib qho tseem ceeb rau qhov no, tab sis thaum cov tsos mob hnyav zuj zus, kuv tau mus ntsib kws kho mob. Lawv tau ua txhua qhov kev kuaj mob uas tsim nyog thiab muab tso rau hauv tsev kho mob. Txwv tsis pub mus noj tshuaj.

Yog li kuv tsis tsuas yog tsis zoo, tab sis kuj yuav luag ploj ntawm kuv qhov kev noj qab haus huv. Ceev faj nrog cov tshuaj no thiab nrhiav cov kws paub tshwj xeeb uas yuav saib xyuas koj zoo thaum kho.

Daniyees, 29 xyoos, Omsk

Kuv raug kev txom nyem los ntawm cov mob muaj keeb ntawm hypercholesterolemia. Qib ntawm lipids hauv cov ntshav tau yuav tsum tau txo tas li. Kuv ua qhov no nrog cov tshuaj zoo li Atorvastatin. Kev ntim khoom tsis kim heev thaum piv nrog cov neeg ua haujlwm txawv teb chaws, tab sis cov nyhuv yog tib yam. Kuv tuaj yeem pom cov cuab yeej no rau txhua tus neeg uas tau ntsib tus kab mob zoo ib yam. Yog tias kho tau raws li kev pom zoo los ntawm tus kws kho mob, koj tuaj yeem nyob tas lub neej.