TromboMag® (TromboMag)
Cov tshuaj tsis sib haum xeeb ua rau muaj kev cuam tshuam ntawm cyclooxygenases 1 thiab 2, uas koom nrog kev coj ua hauv kev tswj hwm ntawm prostaglandin synthesis (ua rau o thiab tsim kev mob tshwm sim).
Thrombopol ntsiav tshuaj muaj analgesic, anti-inflammatory, antipyretic zoo.
Cov nquag tivthaiv yog acetylsalicylic acid.
Ib qho kev txo qis hauv prostaglandins nyob rau hauv thermoregulation chaw ua rau muaj kev poob hauv lub cev kub vim tawm hws ntau zog thiab ua paug ntawm daim tawv nqaij ua ke. Raws li qhov nruab nrab ntawm lub hauv nruab nrab thiab lub ntsiab lus ntawm lub ntsiab tivthaiv, qhov ua haujlwm analgesic tau tiav.
Cov tshuaj txo cov haujlwm tsawg mob ntsws vwm vim yog kev tsuj tawm ntawm kev ua ke ntawm thromboxane A2 hauv cov ntshav los ntawm platelets. Cov tshuaj maj mam txo cov kev nplaum thiab kev sau cov platelets.
Ua tiav nrog kev pab ntawm yeeb tshuaj Thrombopol (ib koob tshuaj) antiplatelet nyhuv cawm 7 hnub. Hauv cov neeg mob uas tsis muaj lub hlwb tsis khov, cov tshuaj yuav txo tau txoj kev pheej hmoo ntawm myocardial infarction, kev ploj tuag.
Cov tshuaj yog siv rau kev tiv thaiv thawj thiab theem nrab ntawm myocardial infarction.
Ib koob tshuaj txhua hnub ntawm 6 grams nce lub sijhawm prothrombin, inhibits synthesis ntawm prothrombin hauv daim siab mob siab.
Raws li kev nqis tes ua ntawm acetylsalicylic acid, qhov kev sib txuam ntawm coagulation yam poob qis (2,7,9,10), kev ua si ntshav fibrinolytic nce.
Thaum muaj kev cuam tshuam kev phais mob, cov tshuaj tsub kom ntau zaus ntawm cov ntshav hemorrhagic, ua rau muaj qhov los ntshav ntau ntxiv.
Thrombopol tshuaj stimulates txheej txheem excretion uric acid (cov txheej txheem ntawm uric acid reabsorption nyob rau hauv ob lub raum tau cuam tshuam).
Kev ntsuas rau siv
Cov tshuaj yog tshuaj rau kev nyem kev hnov mob mob (mob me, hnyav) ntawm ntau yam hauv paus: mob hniav, mob taub hau, mob taub hau, neuralgia, algodismenorea, radicular syndrome, lumbago, myalgia, arthralgia, mob taub hau nrog ntsoos ntsoos cawv mob.
Cov tshuaj yeeb yog siv rau febrile mob tawm tsam keeb kwm ntawm kev kis tus kab mob thiab mob pathology.
Cov Yuav Tsum Muaj
Cov lus qhia rau kev siv ntawm thrombopol tsis pom zoo kom muab tshuaj rau cov tshuaj rau qhov tsis haum rau acetylsalicylic acid, nrog hemorrhagic diathesislub plab zom zaws, nrog rau kev hloov pauv thiab ulcerative ntawm lub plab zom mov hauv qhov mob siab, nrog mob ntsws asthma (ib daim ntawv uas ua los ntawm kev noj salicylates thiab cov tshuaj NSAID), nrog kev kho mob tib lub sijhawm methotrexate ntawm qhov ntau npaum ntawm 15 toj ib lub lis piam lossis ntau dua.
Cov tshuaj Thrombopol tsis raug kho rau kev xeeb tub, thaum pub niam mis. Cov tshuaj yog contraindicated rau hauv cov menyuam yaus.
Sab sij huam
Thrombopol tuaj yeem ua rau xeev siab, Tus Mob Reye Syndrome (kev loj hlob ntawm daim siab tsis ua hauj lwm hauv kev sib txuam nrog cov kev nce qib ceev ceev rog ua lub siab thiab concomitant encephalopathy), kev tsis haum (hauv daim ntawv ntawm bronchospasm, angioedema thiab daim tawv nqaij ua pob), raws plab, ua kom ntshav khov, thrombocytopenia, gastralgia, qab los tsawg, mob leukopenia.
Kev kho mob ntev ntev tuaj yeem ua rau mob taub hau, kiv taub hau, los ntshav, hypocoagulation, voos thiab viav vias ua rau lub plab zom mov, ntuav, bronchospasm, tinnitus, thiab txo qhov pom ntawm lub qhov muag pom. interstitial jade, pom kev txawv txav, o, nce cov tsos mob ntawm lub plawv tsis ua haujlwm, aseptic mob hlwbnephrotic syndrome, lub raum tsis ua haujlwm, papillary necrosis, prerenal azotemia nyob rau hauv nrog hypercalcemia thiab hypercreatininemia, nce daim siab enzymes.
Thrombopol, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)
Thrombopol yog noj ntawm qhov ncauj. Anti-inflammatory thiab analgesic zoo yog exerted los ntawm koob tshuaj ntawm cov tshuaj nyob rau hauv dhau ntawm 400-500 mg.
Nrog rau mob thiab febrile syndrome teem taw 0.5-1 grams tauj ib hnub (3 koob tshuaj).
Lub chav kawm ntawm kev kho mob yuav tsum tsis pub ntau tshaj 2 lub lis piam. Kev noj tshuaj ib zaug rau effervescent cov tshuaj yog 0.25-1 grams (3-4 zaug hauv ib hnub).
Noj ntau dhau
Cov tsos mob ntau dhau: ua ntuav, xeev siab, ua pa sai, pom kev, hnov lus thiab pom kev tsis meej, mob taub hau, tsaug zog. Ntawm ib koob tshuaj ntawm cov feem cuam tshuam ntawm ntau tshaj 500 mg rau ib kg, qhov muaj txiaj ntsig yuav ua tau yog qhov ua tau.
Yaug lub plab, txhuav qhov ntuav, muab cov pa hluav taws. Koj tsis tuaj yeem coj barbiturates. Tsis muaj cov tshuaj antidote.
Kev sib txuam
Thrombopol yog tuaj yeem txhim kho cov tshuaj lom methotrexatetxo nwslub raum kev ntshiab.
Cov tshuaj pab kho qhov ua tau zoo ntawm heparin, narcotic analgesics, indirect anticoagulantscov kab mob hypoglycemic, cov tshuaj antiplatelet, thrombolyticssulfonamides.
Acetylsalicylic acid txo cov kev ua haujlwm ntawm kev noj tshuaj (furosemide, spironalokton), cov tshuaj tiv thaiv kab mob, uricosuric tshuaj kho mob(sulfinpyrazone, benzbromarone).
Ethanol-npaj npaj, ethanol nws tus kheej thiab glucocorticosteroids nce ntxiv qhov kev puas tsuaj ntawm cov tshuaj rau ntawm phab ntsa mucous ntawm lub plab zom mov, uas tuaj yeem ua rau mob plab zom mov.
Thrombopol nce qib ntawm barbiturates, digoxin thiab lithium ntsev hauv cov ntshav.
Kev nqus tau poob qis nrog kev kho mob kom zoo ib yam tshuaj tiv thaiv kab mob.
Myelotoxic tshuaj txhim kho cov nyhuv hematotoxic ntawm thrombopol.
Cov lus qhia tshwj xeeb
Lub chav kawm ntawm kev noj cov tshuaj acetylsalicylic acid thiaj li ua tiav cov nyhuv analgesic tsis tau nrog kws kho mob yuav tsum tsis pub tshaj 5 hnub.
Thrombopol yog tsis kho raumob kis myocarditisrheumatoid kev mob caj dab, rheumatism, pericarditis thiab rheumatic chorea.
Cov tshuaj raug muab tso tseg 5-7 hnub ua ntej muaj kev tuaj yeem kho mob.
Lub sij hawm ntev txoj kev kho yuav tsum yog kev kuaj quav thiab kuaj ntshav.
Hauv cov menyuam yaus, kev noj tshuaj Thrombopol tuaj yeem ua rau Reye's syndrome (nce rau daim siab, qhov kev loj hlob ntawm lub sijhawm mob encephalopathy, mob ntev, tsis nco qab ntuav).
Ib txhij kev kho mob ntawm cov tshuaj uas ua rau neutrality acidity ntawm lub plab kua txiv, muaj peev xwm txo tau cov kev tsis haum xeeb ntawm acetylsalicylic acid ntawm lub plab ntawm cov phab ntsa ntawm cov hnyuv.
Thrombopol yog tus yam ntxwv teratogenic cov teebmeem (ua ntej qhov kaw ntawm lub plab hlab ntsha, ua kom lub qhov ncauj sab sauv thiab lwm yam kev hloov ntawm tus me nyuam hauv plab).
Hauv cov neeg mob gout, cov tshuaj yuav ua rau muaj mob hnyav vim tias txo qis uric acid tsis pom zoo thaum noj cov tshuaj acetylsalicylic acid.
Ib qho kev tsis kam lees haus dej haus cawv thaum lub sijhawm tag nrho kev kho mob yog qhov yuav tsum tau ua.
Yuav siv li cas: noj ntau thiab hom tshuaj kho
Sab hauv, 1-2 teev tom qab noj mov, 1 lub sijhawm hauv ib hnub.
Cov ntsiav tshuaj ntawm TromboMag npaj tau nqos tag nrho (tuaj yeem zom lossis zom kom zoo), ntxuav nrog dej.
Cov tshuaj yog npaj rau kev siv sijhawm ntev. Lub sijhawm tiv thaiv yog txiav txim los ntawm tus kws kho mob.
Thawj qhov kev tiv thaiv ntawm cov kab mob plawv, xws li thrombosis thiab mob plawv tsis ua hauj lwm, muaj cov kev pheej hmoo (piv txwv li ntshav qab zib, hyperlipidemia, kub siab, rog rog, haus luam yeeb, muaj hnub nyoog laus)
Thawj hnub - 1 ntsiav tshuaj muaj 150 mg ntawm acetylsalicylic acid, tom qab ntawd 1 lub ntsiav tshuaj muaj 75 mg ntawm acetylsalicylic acid.
Kev tiv thaiv ntawm myocardial infarction thiab txog hlab ntshav thrombosis
1 ntsiav tshuaj muaj 75 mg lossis 150 mg ntawm acetylsalicylic acid.
1 ntsiav tshuaj muaj 75 mg lossis 150 mg ntawm acetylsalicylic acid.
Kev tiv thaiv ntawm thromboembolism tom qab kev phais mob vascular (e.g. coronary artery bypass grafting, percutaneous transluminal coronary angioplasty)
1 ntsiav tshuaj muaj 75 mg lossis 150 mg ntawm acetylsalicylic acid.
Yog tias koj plam ib lossis ntau dua ntawm cov tshuaj ThromboMag, koj yuav tsum noj lub sijhawm ploj ntawm cov tshuaj sai thaum tus neeg mob nco qab qhov no. Txhawm rau zam kom tsis txhob txhaj tshuaj ntau ntxiv, koj yuav tsum tsis txhob noj lub ntsiav tshuaj uas ploj lawm yog tias lub sijhawm siv sijhawm ntxiv los yuav txog.
Peculiarities ntawm kev coj thaum thawj tswj hwm lossis tshem tawm ntawm cov tshuaj tsis tau pom.
Pharmacological kev txiav txim
Lub tshuab ua haujlwm ntawm cov tshuaj tiv thaiv kev ua kom tsis haum ntawm acetylsalicylic acid (ASA) yog ua raws li kev tsis tuaj yeem ua rau lub zog ntawm cyclooxygenase enzyme (COX-1), vim tias qhov uas thromboxane A2 synthesis yog txhaws thiab platelet aggregation yog suppressed.
Cov txiaj ntsig los tiv thaiv kev sib txuas lus feem ntau tau hais tawm hauv platelets, txij li lawv tsis tuaj yeem rov coj los ua ke nrog COX. Nws ntseeg tau tias ASA muaj lwm cov txheej txheem rau kev txo cov kabmob platelet, uas nthuav dav nws txoj hauv kev hauv ntau cov kab mob vascular. ASA kuj tseem muaj cov tshuaj los tiv thaiv, antipyretic thiab analgesic zoo.
Magnesium hydroxide - ib qho antacid, txo cov kev tsis haum xeeb ntawm ASA ntawm lub plab zom mov.
Cev xeeb tub thiab lactation
Kev siv cov tshuaj salicylates hauv kev txhaj tshuaj ntau rau thawj lub hlis thaum cev xeeb tub muaj feem cuam tshuam nrog qhov nce ntawm cov me nyuam hauv plab kev loj hlob tsis zoo (cais tawm ntawm lub qhov ncauj sab sauv, lub plawv tsis zoo). Kev siv cov tshuaj nyob rau hauv thawj peb lub hlis ntawm cev xeeb tub yog contraindicated. Hauv lub hlis thib ob ntawm cev xeeb tub, cov tshuaj muaj peev xwm tsuas yog tau coj mus rau hauv qhov kev ntsuam xyuas nruj ntawm qhov sib piv ntawm cov txiaj ntsig ntawm kev kho mob leej niam thiab muaj kev pheej hmoo rau tus me nyuam hauv plab, hauv cov koob tshuaj tsis pub tshaj 150 mg / hnub rau lub sijhawm luv. Hauv lub hlis thib peb ntawm cev xeeb tub, salicylates hauv kev txhaj tshuaj ntau dua (ntau dua 300 mg / hnub) ua rau inhibition ntawm kev ua haujlwm, ua ntej ntawm txoj hlab ntaws hauv lub menyuam hauv plab, nce ntshav hauv niam thiab tus menyuam, thiab siv tam sim ntawd ua ntej yug menyuam tuaj yeem ua rau mob ntshav khov, tshwj xeeb tshaj yog cov menyuam tsis tau yug menyuam ntxov. Kev siv cov tshuaj nyob rau hauv III ntawm lub sijhawm cev xeeb tub yog contraindicated.
Salicylates thiab lawv cov metabolites hauv cov khoom me me kis mus rau niam mis. Cov ntaub ntawv kho mob txhawm rau ntsuas kev nyab xeeb ntawm acetylsalicylic acid lub sijhawm pub mis niam tsis txaus. Ua ntej sau cov tshuaj acetylsalicylic acid lub sijhawm lactation, kev kwv yees cov txiaj ntsig ntawm kev siv tshuaj kho mob thiab kev pheej hmoo rau menyuam yaus yuav tsum raug ntsuas. Kev noj cov salicylates ntau thaum lub sijhawm lactation tsis yog nrog kev txhim kho cov nyom hauv tus menyuam thiab tsis tas yuav tsum tsis tsum txog kev pub niam mis rau menyuam noj. Txawm li cas los xij, yog tias koj xav tau kev siv tshuaj ntev ntev, kev pub niam mis yuav tsum nres tam sim ntawd.
Nosological kev faib tawm (ICD-10)
Zaj duab xis-coated ntsiav tshuaj | 1 tab. |
yam tshuaj: | |
acetylsalicylic acid | 75/150 mg |
magnesium hydroxide | 15.2 / 30.39 mg |
tus zam: pob kws nplej siab - 9.5 / 19 mg, qos hmoov txhuv nplej siab - 2/4 mg, MCC - 9.07 / 18.15 mg, citric acid - 3.43 / 6.86 mg, magnesium stearate - 0.15 / 0, 3 mg | |
zaj duab xis sheath: hypromellose - 0.36 / 0.72 mg, macrogol 4000 - 0.07 / 0.14 mg, talc - 0.22 / 0.44 mg |
Tsuas tshuaj thiab tswj hwm
Sab hauv 1-2 teev tom qab noj mov, 1 lub sijhawm ntawm ib hnub.
Cov ntsiav tshuaj ntawm TromboMag ® kev npaj tau nqos tag nrho (tuaj yeem zom lossis zom), ntxuav nrog dej.
Cov tshuaj TromboMag ® tau npaj rau kev siv mus sij hawm ntev. Lub sijhawm tiv thaiv yog txiav txim los ntawm tus kws kho mob.
Thawj qhov kev tiv thaiv ntawm cov kab mob plawv, xws li thrombosis thiab mob plawv tsis ua hauj lwm, muaj cov kev pheej hmoo (piv txwv li ntshav qab zib, hyperlipidemia, kub siab, rog dhau, haus luam yeeb, muaj hnub nyoog laus). Nyob rau thawj hnub - 1 lub rooj. ThromboMag ® kev npaj muaj 150 mg ntawm acetylsalicylic acid, tom qab ntawd - 1 lub rooj. ThromboMag ® muaj 75 mg ntawm acetylsalicylic acid.
Kev tiv thaiv ntawm rov ua dua myocardial infarction thiab cov hlab ntsha thrombosis. 1 tab. ThromboMag ® muaj 75 lossis 150 mg ntawm acetylsalicylic acid.
Tsis ruaj tsis khov angina pectoris. 1 tab. ThromboMag ® muaj 75 lossis 150 mg ntawm acetylsalicylic acid.
Kev tiv thaiv ntawm thromboembolism tom qab kev phais mob vascular (e.g. coronary artery bypass grafting, percutaneous transluminal coronary angioplasty). 1 tab. ThromboMag ® muaj 75 lossis 150 mg ntawm acetylsalicylic acid.
Thaum hla dhau ib lossis ntau qhov kev siv tshuaj ntawm TromboMag ® kev npaj, nws yog qhov yuav tsum tau noj cov koob tshuaj uas ploj lawm thaum tus neeg mob nco qab qhov no. Txhawm rau zam kom tsis txhob txhaj tshuaj ntau ntxiv, koj yuav tsum tsis txhob noj lub ntsiav tshuaj uas ploj lawm yog tias lub sijhawm siv sijhawm ntxiv los yuav txog.
Peculiarities ntawm kev coj thaum thawj tswj hwm lossis tshem tawm ntawm cov tshuaj tsis tau pom.
Daim ntawv tso tawm
Cov ntsiav tshuaj zaj duab xis-75 mg + 15.2 mg lossis 150 mg + 30.39 mg. 10 tab. hauv blister sawb ntim ua los ntawm cov ntawv luam tawm aluminium ntawv ci thiab txhuas ntawv ci, laminated PVC thiab polyamide zaj duab xis. 3 lossis 10 lub hlwv muab tso rau hauv ib pob khoom ntawm cardboard.
Chaw tsim tshuaj paus
Hemofarm LLC, Russia. 249030, Kaluga Thaj Tsam, Obninsk, Kievskoye sh., 62.
Xov tooj: (48439) 90-500, fax mus: (48439) 90-525.
Lub npe thiab chaw nyob ntawm tus neeg muaj cai nyob hauv uas lawv tau kos npe rau daim ntawv pov thawj / koom haum lees txais cov lus thov tau tawm. Nizhpharm JSC, Russia, 603950, Nizhny Novgorod, GSP-459, ul. Salgan, 7.
Xovtooj: (831) 278-80-88, fax: (831) 430-72-28.
Cov Tshuaj Pharmacokinetics
Ib zaug nyob rau hauv txoj hnyuv plab, ASA tau nqus sai thiab yuav luag tag. Nrog kev sib txig sib xyaw, kev nqus nqus tau qeeb. Nws raug qee yam metabolism hauv thaum lub sij hawm nqus.
Thaum lub sijhawm thiab tom qab nqus, ASA yog biotransformed rau hauv lub ntsiab metabolite - salicylic acid, uas tseem yog cov metabolized nyob rau hauv kev cuam tshuam ntawm enzyme (feem ntau hauv daim siab), uas ua rau muaj kev tsim cov metabolites xws li salicylic acid, glucuronide salicylate thiab phenyl salicylate, uas pom nyob hauv ntau lub cev thiab cov nqaij. Hauv cov poj niam, ASA metabolism qeeb qeeb (vim yog qis dua kev ua haujlwm ntawm cov enzymes hauv cov ntshav dej).
Qhov siab tshaj plaws ntshav ntawm ASA tau txog 10-20 feeb tom qab noj ThromboMag qhov ncauj, salicylic acid - tom qab 18-120 feeb. Acetylsalicylic thiab salicylic acids khi rau qib siab rau cov ntshav plasma protein thiab tau muab faib sai sai hauv lub cev. Qhov khi ntawm salicylic acid rau cov ntshav plasma protein tsis yog-ib txoj kab thiab nyob ntawm qhov kev cia siab. Thaum muaj qhov ntau (0.4 mg / ml) - txog 75%.
Lub bioavailability ntawm acetylsalicylic acid yog 50-68%, salicylic acid - 80-100%. Salicylic acid hla dhau qhov chaw tiv thaiv kab mob thiab tso rau hauv niam mis.
Hauv cov menyuam tshiab, cov poj niam cev xeeb tub, thiab cov neeg mob lub raum tsis ua haujlwm, cov tshuaj salicylates tuaj yeem tshem cov bilirubin los ntawm kev koom nrog albumin thiab ua rau kev txhim kho bilirubin encephalopathy.
ASA thiab nws cov khoom ua kom tau ua paug yog sab hauv ob lub raum. Thaum noj ThromboMag hauv koob tshuaj tsawg, ib nrab-lub neej (T½) ntshav plasma acetylsalicylic acid yog 15-20 feeb, salicylic acid yog 120-180 min. Thaum noj cov tshuaj hauv qhov siab ntau vim yog qhov saturation ntawm cov enzymatic systems T½ nce siab.
Tsis zoo li lwm yam salicylates, non-hydrolyzed ASA tsis ntau ntau hauv cov ntshav cov ntshav thaum noj ntau zaus. Nrog lub raum ua haujlwm li qub, 80-100% ntawm qhov tau txais ntawm ASA raug tso tawm los ntawm lub raum hauv 24-72 teev.
Lub hydroxide uas yog ib feem ntawm ThromboMag magnesium tsis cuam tshuam rau qhov kev nyab xeeb ntawm cov neeg ASA.
Yeeb tshuaj sib cuam tshuam
Cov nyhuv antiplatelet ntawm ASA raug txo los ntawm: colestyramine, ibuprofen, systemic glucocorticosteroids thiab antacids uas muaj cov tshuaj magnesium thiab / lossis aluminium hydroxide.
ASA txhim kho cov nyhuv thiab ua rau muaj kev pheej hmoo ntau ntxiv thaum siv ib txhij nrog methotrexate (txo nws qhov kev ua kom lub raum thiab tshem tawm nws los ntawm cov ntshav plasma protein) thiab valproic acid (txav nws los ntawm cov ntshav plasma protein).
Ib yam li lwm cov NSAIDs, nyob rau hauv cov koob tshuaj siab, ASA tuaj yeem txo qhov kev ntxim siab hypotensive ntawm diuretics (inhibiting cov synthesis ntawm lub raum prostaglandins thiab txo tus nqi glomerular filtration) thiab cov tshuaj tiv thaiv antihypertensive. Hauv tshwj xeeb, vim muaj kev sib tw txhaws ntawm prostacyclin synthesis, cov tshuaj muaj peev xwm txo cov nyhuv ntawm angiotensin hloov mus rau enzyme (ACE) inhibitors.
Hauv kev txhaj tshuaj tsawg, ASA ua rau tsis muaj zog ntawm cov kab mob uricosuric (sulfinpyrazone, probenecid, benzbromarone), cov kev sib tw hauv lub plab hlaus rov qab ua paug ntawm uric acid.
ASA txhim kho cov nyhuv thiab nce qhov kev pheej hmoo ntawm kev phiv los ntawm cov tshuaj hauv qab no:
- lwm cov NSAIDs thiab narcotic analgesics (vim yog qhov sib txuam ntawm kev txiav txim),
- carbonic anhydrase inhibitors, piv txwv li, acetazolamide (kev txhim kho ntawm acidosis loj thiab muaj tshuaj lom muaj zog rau lub hauv nruab nrab cov hlab ntsha tau muaj),,
- digoxin thiab lithium (lawv qhov ua haujlwm hauv lub raum tsawg zuj zus, ntshav ntau ntxiv, ntshav ntau yuav tsum tau kuaj xyuas thiab kev kho qhov tsim nyog),,
- xaiv serotonin reuptake inhibitors, suav nrog paroxetine thiab sertraline (vim qhov kev txiav txim siab, nrog kev pheej hmoo ntawm ntshav los ntshav hauv lub plab hnyuv sab sauv),
- cov tshuaj antiplatelet (suav nrog clopidogrel thiab dipyridamole), anticoagulants tsis ncaj (nrog rau ticlopidine thiab warfarin), heparin, tshuaj thrombolytic (vim yog tawm ntawm cov ntshav plasma protein thiab synergism ntawm cov kev kho mob tseem ceeb),
- qhov ncauj hypoglycemic tus neeg sawv cev, uas yog derivatives ntawm sulfonylurea, thiab insulin ASA hauv kev noj tshuaj ntau dua txhua hnub (ntau tshaj 2000 mg) nws tus kheej muaj hypoglycemic thaj chaw, thiab tseem tshem tawm sulfonylurea derivatives los ntawm kev sib txuas nrog plasma protein,
- sulfonamides, suav nrog cov co-trimoxazole (ASA hloov lawv los ntawm kev sib txuas lus nrog cov ntshav plasma thiab ua rau muaj kev nce siab hauv cov ntshav ntshav),
- ethanol (nws cov nyhuv ua kev puas rau ntawm cov qog ua kua ntawm lub plab zom mov tau txhim kho, thiab qhov kev pheej hmoo ntawm cov hnyuv tawm tuaj).
Cov qauv ntawm ThromboMag yog: Cardiomagnyl, Thrombital, Thrombital Forte, Phasostabil.
Tshuaj los qhia
Thawj prophylaxis ntawm cov kab mob plawv xws li thrombosis thiab mob plawv tsis ua hauj lwm nrog kev pheej hmoo (piv txwv li ntshav qab zib mellitus, hyperlipidemia, kub siab, rog, haus luam yeeb, muaj hnub nyoog laus), kev tiv thaiv ntawm myocardial infarction thiab cov hlab ntshav thrombosis, kev tiv thaiv ntawm thromboembolism tom qab kev phais mob kev cuam tshuam vascular (kev kho mob rau cov leeg ntshav mob hla ntawm kev sib tsoo, percutaneous transluminal coronary coronary angioplasty), tsis khov kho angina pectoris.
ICD-10 cov lis dej numICD-10 code | Kev taw qhia |
I20.0 | Tsis khov tsis khov lub taub hau |
I21 | Mob myocardial infarction |
I26 | Pulmonary embolism |
I50.1 | Sab laug ventricular tsis ua haujlwm |
I74 | Embolism thiab leeg txoj hlab ntshav thrombosis |
I82 | Embolism thiab thrombosis ntawm lwm cov leeg ntshav |
Kev noj tshuaj ntxiv
Cov tshuaj tau noj qhov ncauj, 1-2 teev tom qab noj mov, 1 zaug / hnub. Cov ntsiav tshuaj yuav tsum nqos tag nrho nrog dej. Yog tias qhov xav tau, lub ntsiav tshuaj tuaj yeem tawg nyob rau hauv ib nrab, zom lossis ua ntej npaj rau hauv av.
Cov tshuaj yog npaj rau kev siv sijhawm ntev. Lub sijhawm tiv thaiv yog txiav txim los ntawm tus kws kho mob.
Rau thawj txoj kev tiv thaiv cov kab mob plawv xws li thrombosis thiab mob plawv tsis ua hauj lwm hauv thaj chaw muaj kev pheej hmoo (piv txwv li, ntshav qab zib mellitus, hyperlipidemia, mob ntshav nce ntshav siab, rog rog, haus luam yeeb, muaj hnub nyoog laus), 1 tab. ib qho kev npaj muaj acetylsalicylic acid nyob rau hauv ib koob tshuaj ntawm 150 mg rau thawj hnub, tom qab ntawd 1 tab. ib qho kev npaj muaj acetylsalicylic acid nyob rau hauv ib koob tshuaj 75 mg 1 zaug / hnub.
Rau kev tiv thaiv ntawm mob rov qab myocardial infarction thiab cov hlab ntsha thrombosis, 1 kab. ib qho kev npaj muaj acetylsalicylic acid nyob rau hauv ib koob tshuaj 75-150 mg 1 zaug / hnub.
Txog kev tiv thaiv ntawm thromboembolism tom qab kev phais mob ntawm cov nkoj (hlab ntshav leeg hla kev los ntawm kev sib tsoo, percutaneous transluminal coronary angioplasty), 1 tab. ib qho kev npaj muaj acetylsalicylic acid nyob rau hauv ib koob tshuaj 75-150 mg 1 zaug / hnub.
Nrog lub pob taws tsis ruaj khov, 1 tab. ib qho kev npaj muaj acetylsalicylic acid nyob rau hauv ib koob tshuaj 75-150 mg 1 zaug / hnub.
Yog tias koj plam ib lossis ntau dua ntawm cov tshuaj, koj yuav tsum noj lub sijhawm ploj ntawm cov tshuaj kom sai li thaum tus neeg mob nco qab qhov no. Txhawm rau zam kom tsis txhob txhaj tshuaj ntau ntxiv, koj yuav tsum tsis txhob noj lub ntsiav tshuaj uas ploj lawm yog tias lub sijhawm siv sijhawm ntxiv los yuav txog.
Peculiarities ntawm kev ua ntawm cov tshuaj nyob rau ntawm thawj koob tshuaj lossis tshem tawm ntawm cov tshuaj tsis tau pom.
Sab sij huam
Nyob rau hauv dav dav, npaj muaj nrog no sib xyaw ua ke tau zoo zam.
Los ntawm cov kab mob hauv plab: feem ntau - mob taub hau, pw tsaug zog, ua tsis txaus ntseeg - kiv taub hau, tsaug zog, tsis tshua muaj - tinnitus, mob hlab ntsha hauv ntshav.
Los ntawm cov ntshav hemopoietic: feem ntau heev - nce los ntshav, tsis tshua muaj - ntshav txhaws, tsis tshua muaj heev - mob ntshav qog, hypoprothrombinemia, thrombocytopenia, neutropenia, leukopenia, eosinophilia, agranulocytosis. Muaj cov ntaub ntawv tshaj tawm ntawm cov neeg muaj mob hemolysis thiab hemolytic anemia rau cov neeg mob uas muaj ntshav qabzib ntau-6-phosphate dehydrogenase tsis txaus.
Los ntawm cov txheej txheem ua pa: feem ntau - bronchospasm.
Los ntawm cov txheej txheem hauv plab: feem ntau - kub siab, feem ntau - xeev siab, ntuav, ua tsis tau - mob hauv plab, mob rau ntawm lub plab zom mov ntawm lub plab thiab duodenum, mob plab zom mov, tsis tshua muaj - perforation ntawm lub plab rwj lossis duodenal mob rwj, nce kev ua haujlwm ntawm daim siab enzymes , tsis tshua muaj tshwm sim - stomatitis, esophagitis, erosive qhov txhab ntawm lub plab hnyuv (nrog rau nrog nruj), colitis, chim siab plob tsis so tswj syndrome.
Kev tsis haum tshuaj: ua haujlwm tsis xws luag - urticaria, Quincke's edema, tawv nqaij ua pob khaus, khaus, rhinitis, o ntawm lub qhov ntswg mob, tsis tshua muaj tshwm sim - anaphylactic shock, cardiorespiratory syndrome.
Lwm yam: tsis tshua muaj tshwm sim - lub raum tsis ua haujlwm.