Acarbose (Acarbose) | > Kev khomob thiab kev tiv thaiv

Kev sib tw thiab thim rov qab inhibits pancreatic alpha-amylase (hydrolyzes polysaccharides rau oligosaccharides) thiab cov plab hnyuv membrane-khi alpha-glucosidases (zom oligo-, tri- thiab disaccharides rau cov piam thaj thiab lwm yam monosaccharides) hauv cov lumen ntawm cov hnyuv me. Txo cov kev tsim thiab nqus ntawm cov piam thaj hauv cov hnyuv, txo qis tom qab hyperglycemia, muaj kev hloov pauv nyob rau txhua hnub ntawm cov piam thaj hauv cov ntshav. Tsis nce insulin nce ntxiv thiab tsis ua rau cov ntshav qog ntshav qab zib.

Hauv kev sim tshuaj hauv vitro thiab hauv vivo tsis muaj pov thawj ntawm mutagenicity. Kev tswj hwm cov nas nrog zaub mov tsis cuam tshuam rau kev ua kom muaj tub ki thiab tag nrho kev muaj me nyuam.

Kwv yees li 35% ntawm cov koob tshuaj muab tau los ntawm lub plab zom mov, tej zaum nyob rau hauv daim ntawv ntawm metabolites (ntawm uas 2% yog nyob rau hauv daim ntawv tseem ceeb), bioavailability yog 1-2%. C_max ua tiav tom qab 1 teev, metabolites - tom qab 14-24 teev. Hauv cov neeg mob raum tsis ua haujlwm (Cl creatinine 2) C_max nce 5 zaug, hauv cov neeg laus - los ntawm 1.5 zaug. Nws yog metabolized tshwj xeeb hauv cov hnyuv plab, feem ntau los ntawm cov kab mob plab hnyuv thiab qee qhov zom zaws, nrog kev tsim tsawg kawg 13 lub tebchaw. Cov khoom noj tseem ceeb tau txheeb pom tias yog derivatives ntawm 4-methylpyrogallol (hauv daim ntawv ntawm sulfate, methyl thiab glucuronic conjugates). Ib qho tshuaj metabolite, uas yog ib qho khoom lag luam ntawm qhov txav ntawm cov kua nplaum nyob rau hauv acarbose, muaj peev xwm inhibit alpha glucosidase. Cov tshuaj tsis haum rau lub cev (li 51% ntawm koob tshuaj) yog txau nrog quav rau 96 teev. Kwv yees li 34% ntawm cov koob tshuaj tau tawm los ntawm lub raum ua cov tshuaj metabolites, tsawg dua 2% - tsis hloov pauv thiab hauv daim ntawv tshuaj ua kom lub cev muaj zog. T_1/2 nyob rau theem kev faib khoom - 4 teev, hauv theem ntawm kev zam - 10 teev

Kev siv tshuaj tiv thaiv Acarbose

Hom 2 mob ntshav qab zib mellitus nrog kev kho kev noj haus tsis muaj txiaj ntsig (qhov kev kawm yuav tsum yog tsawg kawg 6 lub hlis) lossis sulfonylurea tsis txaus ntseeg tiv thaiv kev noj zaub mov kom tsis tshua muaj rog, hom 1 mob ntshav qab zib mellitus (ua ib feem ntawm kev sib xyaw ua ke), hom 2 mob ntshav qab zib mellitus tiv thaiv (nyob rau hauv cov neeg mob uas tsis haum piam thaj nyob rau hauv ua ke nrog nrog kev noj haus thiab qoj ib ce).

Cov Yuav Tsum Muaj

Cov kab mob siab ntsws, mob ntshav qab zib ketoacidosis, mob rau daim siab, mob plab thiab mob plab hnyuv, muaj teeb meem los ntawm kev zom zaub mov thiab nqus dej tsis haum (suav nrog malabsorption syndrome, maldigestion syndrome), Remkheld's syndrome, lub plab zom mov nrog cov roj ntau ntxiv, mob plab, plab hnyuv, t .h. muaj ib feem los yog qhov mob ua rau nws, nruj thiab mob plab hnyuv, mob pob txha loj, mob raum tsis ua hauj lwm (creatinine cov ntsiab lus saum toj 2 mg / dl), cev xeeb tub, pub niam mis.

Kev phiv los ntawm cov tshuaj Acarbose

Los ntawm sab ntawm txoj hnyuv: mob plab, pom pob, xeev siab, raws plab, tsis tshua muaj - kev nce qib ntawm kev hloov pauv (ALT thiab AST), mob plab hnyuv, mob daj ntseg, mob siab (mob feem tsawg, muaj tsis txaus nrog lub txiaj ntsig tuag).

Kev tsis haum tshuaj: daim tawv nqaij ua pob, hyperemia, exanthema, urticaria.

Lwm yam: tsis tshua muaj - o.

Kev sib txuam

Cov nyhuv txo cov roj carbon activated thiab lwm cov hnyuv adsorbents, plab enzyme npaj muaj pancreatin lossis amylase. Thiazide diuretics, corticosteroids, phenothiazines, cov thyroid hormones, estrogens, suav nrog raws li ib feem ntawm kev tiv thaiv qhov ncauj, phenytoin, nicotinic acid, sympathomimetics, calcium antagonists, isoniazid thiab lwm yam tshuaj uas ua rau hyperglycemia, ua rau tsis muaj zog txog cov haujlwm tshwj xeeb (ua tau decompensation ntawm ntshav qab zib mellitus), sulfonylureas, insulin, metformin - txhim kho hypoglycemic effect.

Ceev faj ntawm cov tshuaj Acarbose

Nws yog ib qho tsim nyog yuav tsum tau nruj me ntsis ua raws kev noj haus. Nws yuav tsum tau yug los rau hauv lub siab tias cov zaub mov thiab dej haus uas muaj cov khoom noj carbohydrates ntau, cov piam thaj hauv qab zib tuaj yeem ua rau mob plab hnyuv. Kev kho yuav tsum tau ua nyob rau hauv kev tswj hwm ntawm theem ntawm cov piam thaj hauv cov ntshav thiab / lossis zis, glycosylated hemoglobin thiab transaminases hauv thawj xyoo ntawm kev kho mob - 1 zaug hauv 3 hlis thiab tom qab ntawd ib ntu. Kev nce ntxiv rau ntau dua 300 mg / hnub yog nrog los ntawm qhov txuas ntxiv, tab sis me ntsis cov lus qhia txo qis hauv postprandial hyperglycemia nrog tib lub sijhawm nce nyob rau hauv kev pheej hmoo ntawm hyperfermentemia (nce concentration ntawm AST thiab ALT hauv cov ntshav). Nrog rau kev siv sulfonylurea lossis tshuaj insulin ib txhij, nws muaj peev xwm los txhim kho hypoglycemia, uas raug kho los ntawm kev ntxiv cov piam thaj (piam thaj, tab sis tsis sucrose) rau zaub mov, lossis intravenously qhia ntshav qab zib, lossis siv glucagon (hauv kis mob loj). Thaum muaj kev mob ntshav qab zib tsawg, nws yuav tsum tau yug los rau hauv lub siab tias cov zaub mov muaj piam thaj ntau dua maj mam tawg rau hauv fructose thiab qabzib thaum kho thiab tsis tsim nyog rau kev tshem tawm sai ntawm hypoglycemia, nyob rau hauv cov rooj plaub no nws raug nquahu kom siv cov piam thaj hauv kev txhaj tshuaj loj.

Dosage daim ntawv

50 mg thiab 100 mg ntsiav tshuaj

Ib ntsiav tshuaj muaj

cov tshuaj nquag - acarbose 50 lossis 100 mg,

kev zam: colloidal anhydrous silicon dioxide, magnesium stearate, pob kws nplej siab, microcrystalline cellulose.

Cov ntsiav tshuaj los ntawm xim dawb mus dawb nrog lub tinge daj ntawm cov xim, puag ncig ntawm cov duab, nrog tus txaij "G 50" ntawm ib sab thiab kos npe Bayer hla ntawm ib sab (rau kev ntsuas ntawm 50 mg).

Cov ntsiav tshuaj los ntawm xim dawb mus rau xim daj nrog lub ntsej muag daj, lub ntsej muag ຮູບ, nrog lub cim thiab kos "G 100" ntawm ib sab thiab kos cim nyob rau sab nraud (rau ntau npaum ntawm 100 mg).

Cov chaw muag tshuaj

Cov tshuaj pharmacokinetics ntawm acarbose tau kawm tom qab lub qhov ncauj tswj hwm ntawm kev siv tshuaj tua kab mob (200 mg).

Txij li kwv yees li 35% ntawm tag nrho cov xov tooj cua (tas nrho cov tshuaj thiab cov tshuaj tiv thaiv kab mob) raug tso tawm los ntawm lub raum rau 96 teev, nws xav tias qhov degree ntawm kev nqus yog nyob hauv cov kev txwv no.

Plasma tag nrho cov radioactivity ntau yog pom los ntawm ob lub siab. Thawj qhov siab tshaj plaws, sib npaug rau qhov nruab nrab nruab nrab ntawm acarbose ntawm 52.2 + 15.7 μg / L, raug pom tom qab 1.1 + 0.3 teev. Qhov thib ob ncov nruab nrab 586.3 + 282.7 μg / L thiab raug pom tom qab 20.7 + 5.2 teev. Tsis zoo li cov xov tooj cua dav dav, qhov siab tshaj plaws ntawm cov tshuaj tiv thaiv kab mob hauv ntshav yog 10-20 zaug qis dua. Qhov tshwm sim ntawm qhov ncov thib ob tom qab txog 14-24 teev yog pom tseeb vim tias qhov nqus ntawm cov khoom xyaw cov khoom lwj los ntawm qhov tob ntawm txoj hnyuv.

Lub bioavailability ntawm cov tshuaj yog tsuas yog 1-2%. Qhov feem ntau tsis tshua muaj ntau ntawm qhov muaj txiaj ntsig yog qhov tsim nyog vim tias acarbose ua haujlwm tsuas yog nyob hauv txoj hnyuv. Yog li, qhov qis ntawm bioavailability ntawm cov tshuaj tsis cuam tshuam rau kev kho mob.

Cov pom pom tseeb faib tau yog 0.32 l / kg lub cev hnyav.

Kev tshem tawm ib nrab-lub neej rau kev faib tawm thiab tawm qib yog 3.7 + 2.7 teev thiab 9.6 + 4.4 teev, ntsig txog, 51% ntawm cov tshuaj nquag raug tso tawm los ntawm txoj hnyuv tsis pub dhau 96 teev, 1.7% tsis hloov pauv thiab nquag metabolite - dhau los ntawm ob lub raum.

Lub tshuaj nquag ua haujlwm ntawm cov tshuaj Glucobay® - acarbose yog pseudotetrasaccharide ntawm microbial keeb kwm. Glucobay® tuaj yeem siv kho ob qho tib si los ntawm kev siv tshuaj insulin thiab cov ntshav qab zib tsis muaj zog ntawm ntshav qab zib.

Acarbose ua haujlwm nyob rau theem ntawm txoj hnyuv, tiv thaiv kev ua si ntawm cov hnyuv plab me me (alpha-glucosidase), uas koom nrog kev rhuav tshem ntawm di-, oligo- thiab polysaccharides. Raws li qhov tshwm sim, kev noj tshuaj-ncua sij hawm nyob rau hauv kev zom zaub mov ntawm cov khoom noj khoom haus carbohydrates tshwm sim, tom qab los ntawm kev tso tawm qeeb thiab nqus cov piam thaj, uas tau tsim thaum lub sijhawm rhuav tshem ntawm carbohydrates. Yog li, acarbose qeeb thiab txo qhov kev xav tom qab kev nce siab nyob rau hauv cov concentration ntawm cov piam thaj hauv cov ntshav. Vim tias kev nqus ntawm cov piam thaj ntau dua ntawm cov hnyuv, qhov nruab nrab ntawm cov piam thaj thiab nws cov ntshav nruab hnub muaj tsawg. Nyob rau hauv cov ntaub ntawv ntawm kev nce nyob rau hauv lub concentration ntawm glycosylated hemoglobin, acarbose txo nws qib.

Hauv kev sim xaiv, nws tau pom tias hauv cov neeg mob uas pom tias tsis muaj peev xwm txo cov ntshav qabzib, kev tswj hwm ntawm Glucobaya® txo cov kev pheej hmoo ntawm kev mob ntshav qab zib hom 2. Ntxiv rau, nws tau pom tias tib lub sijhawm lawv txo qis kev tshwm sim ntawm cov hlab plawv thiab myocardial infarction.

Kev siv cov Glucobaya® rau cov ntshav qab zib hom 2 txo txoj kev pheej hmoo ntawm kev tsim mob plawv thiab myocardial infarction.

Kev ntsuas rau siv

- kev kho mob ntshav qab zib ntxiv rau txoj kev kho kev noj haus

- kev tiv thaiv tus mob ntshav qab zib hom 2 hauv cov neeg mob uas pom tias muaj cov piam thaj tsis haum * ua ke nrog kev noj haus thiab kev tawm dag zog

* yog txhais raws li ntshav ntshav qab zib concentration 2 teev tom qab cov ntshav qabzib 7.8-11 mmol / l (140-200 mg / dl) thiab yoo cov kua nplaum ntau ntau ntawm 5,6 - 7.0 mmol / l (100-125 mg / dl) )

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj ntawm cov tshuaj yog xaiv los ntawm cov kws kho mob koom nrog ib tus zuj zus rau txhua tus neeg mob, vim tias nws cov txiaj ntsig thiab kev tiv taus sib txawv.

Glucobaya ® cov ntsiav tshuaj ua haujlwm tau zoo yog tias lawv tau noj tam sim ntawd ua ntej noj mov tag nrho, tsis tas yuav zom, nrog rau qhov ua kua, lossis zom nrog thawj feem ntawm cov zaub mov.

Kev kho mob ntshav qab zib ntxiv rau kev noj zaub mov zoo

Tshwj tsis yog muaj lwm qhov kev teev tseg, cov koob tshuaj hauv qab no raug pom zoo:

Thawj koob tshuaj yog 1 ntsiav tshuaj ntawm 50 mg 3 zaug hauv ib hnub nrog txhua pluas noj lossis ½ ntsiav tshuaj ntawm 100 mg 3 zaug hauv ib hnub nrog txhua pluas noj. Yav tom ntej, cov koob tshuaj yuav tsum tau nce rau qhov nruab nrab ib hnub twg ntawm 300 mg ib hnub (2 ntsiav tshuaj ntawm 50 mg 3 zaug hauv ib hnub nrog txhua pluas noj lossis 1 ntsiav tshuaj ntawm 100 mg 3 zaug hauv ib hnub nrog txhua pluas noj).

Qee qhov xwm txheej, yog tias tsim nyog, cov koob tshuaj yuav raug nce rau 200 mg 3 zaug hauv ib hnub nrog txhua pluas mov loj.

Cov koob tshuaj tuaj yeem raug nce ntxiv tom qab 4-8 lub lis piam yog tias qhov tsim nyog siv hauv chaw kho mob tsis tau nyob hauv cov neeg mob ntawm lub koob tshuaj dhau los.

Yog hais tias tus neeg mob, txawm tias muaj kev coj ua nruj rau kev noj haus, kev mob plab thiab mob plab zom zaws, tom qab ntawd qhov kev nce ntxiv ntawm cov tshuaj yuav tsum nres, thiab qee qhov kev txhaj tshuaj txo qis.

Qhov nruab nrab ib hnub ntawm cov tshuaj yog 300 mg rau ib hnub.

Kev tiv thaiv kab mob ntshav qab zib hom 2 hauv cov neeg mob uas muaj kev tiv thaiv ntshav qabzib nrog kev noj mov thiab tawm dag zog

Qhov tshuaj thawj zaug yog 50 mg ib hnub ib zaug (50 ntsiav tshuaj mg lossis ½ 100 mg ntsiav tshuaj ib hnub ib zaug). Lub sijhawm 3 lub hlis, cov koob tshuaj thawj zaug yog maj mam nce ntxiv rau qhov kev pom zoo ntawm koob tshuaj 100 mg 3 zaug hauv ib hnub (2 ntsiav tshuaj ntawm 50 mg lossis 1 ntsiav tshuaj ntawm 100 mg peb zaug ib hnub nrog txhua pluas noj).

Ib qho hloov pauv ntawm cov tshuaj lossis ntau npaum li cas yog tsis tas yuav.

Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo

Hauv cov neeg mob uas lub siab tsis ua hauj lwm zoo, hloov pauv ntawm tsuas tshuaj yog tsis tas yuav tsum muaj.

Tsis muaj kev txwv rau lub sijhawm tag nrho ntawm kev noj tshuaj Glucobay®.

Noj thiab poob ceeb thawj

Qhov no yog qhov teeb meem loj. Cov lus qhia yooj yim xws li lim cov rog kom tsawg thiab nce ntau ntawm cov zaub, nqaij ntses thiab zaub mov hauv cov khoom noj tsis haum rau tib neeg. Raws li txoj cai, ib qho xav noj dab tsi ua rau muaj kev lom zem tshaj plaws, ua kom hnov tsw qab. Thiab thaum lub sijhawm tsis tsuas yog nce phaus, tab sis kuj tau tshem ntawm cov khoom ntau ntxiv. Hmoov tsis zoo, tsis muaj txuj ci tseem ceeb hauv ntiaj teb. Yog tias koj noj ntau calories ntau dua li koj siv, lawv yuav muab tso rau ntawm ob sab.

Tab sis txoj cai no tsis pom tseeb rau txhua tus. Txwv tsis pub, yuav ua li cas piav qhia txog kev tawg sai sai ntawm ntau yam blockers ntawm cov rog thiab carbohydrates? Kev tshaj tawm cog lus rau peb tias koj tuaj yeem txaus siab rau koj cov tais nyiam, tsuas yog tom qab noj tshuaj ntsiav. Thiab txhua yam noj yuav tawm ntawm lub cev yam tsis muaj mob. Puas yog li no - cia peb xam ua ke.

Txhua txhais tau tias zoo

Nws yog qhov yooj yim heev kom tuaj rau txoj kev txiav txim siab no, nws yog qhov txaus los xav txog kev ua lag luam ntawm cov tshuaj niaj hnub los txo qhov hnyav. Ntawm lawv yog cov tshuaj thiab txawm tias siv tshuaj tua kab, tshuaj hormonal. Tsis ntev los no, ib hom tshuaj uas tau npaj los kho cov neeg mob ntshav qab zib tau pib muaj koob meej. Nws yog siv rau qhov poob phaus "Acarbose". Kev tshuaj xyuas ntawm cov neeg uas tau sim cov tshuaj no muaj kev sib txawv ntawm ib leeg, qee tus tsis zoo. Tsis yog, tib neeg yeej poob ceeb thawj, tab sis cov kev mob tshwm sim yog tias cov txiaj ntsig tsis tau zoo siab. Yog li txhua tus neeg muaj lub sijhawm los xav txog qhov yuav tshwm sim, hnub no peb yuav xav txog cov yam ntxwv ntawm cov tshuaj no, nws lub hom phiaj thiab cuam tshuam rau lub cev.

Tsis yog panacea

Tus yeeb ncuab txaus ntshai tshaj plaws ntawm daim duab zoo nkauj yog khoom qab zib. Nws yog qhov nyuaj heev kom tsis kam lees bar lossis ncuav qab zib, ncuav qab zib lossis khoom qab zib. Thiab vim li ntawd, lub cev tau txais cov nyiaj ntawm cov carbohydrates ceev ceev. Tau kawg, koj tsis tuaj yeem siv lawv, tshwj tsis yog koj ua haujlwm lub cev ntawm qhov chaw tsim kho.

Vim li ntawd qhov kev saib xyuas ntawm cov poj niam yog nyiam rau cov tshuaj uas tuaj yeem thaiv cov khoom noj uas yooj yim, vim tias lawv tuaj yeem siv rau qhov hnyav. Muaj ntau qhov kev soj ntsuam sib txawv txog "Acarbose", tab sis koj yuav tsum nco ntsoov tias cov tshuaj no tau tsim tawm los muab kev pabcuam tsim nyog rau cov ntshav qab zib. Lub cev yuag yog nws cov kev mob tshwm sim.

Yam khoom muaj sia

Yog tsis muaj daim ntawv yuav tshuaj los ntawm kws kho mob, yuav luag tsis yooj yim yuav. Ntawm chav kawm, nws tsis zoo li koj yuav tuaj yeem ntseeg tus kws endocrinologist uas koj xav tau nws kho cov kab mob hauv lub cev. Nov yog cov khoom kho mob, kev siv uas yuav tsum tau kho kom zoo. Ntxiv rau, nrog kev sib koom ua ke ntawm "Acarbose" thiab lwm yam tshuaj, cov kev mob tshwm sim tuaj yeem yuav nce ntxiv.

Cov tshuaj phiv yog acarbose, tus thaiv ntawm alpha-glucosidase, ib qho enzyme ntawm lub tsev txiav. Nws zom cov piam thaj ntau dhau rau cov piam thaj thiab fructose. Cia peb xaus ntawm no me ntsis, vim tias nws yog ib qho tseem ceeb kom nkag siab tias cov tshuaj ua haujlwm li cas thiab vim li cas "Acarbose" pab txhawb rau kev poob phaus. Kev tshuaj xyuas ntawm cov kws kho mob tsis tshua zoo, lawv tsuas tsis qhia kom sim ua rau lawv noj qab haus huv.

Yog li, ib qho alpha glucosidase inhibitor inhibits qhov kev zom thiab nqus ntawm cov carbohydrates hauv txoj hnyuv me. Yog li, qhov nce hauv cov piam thaj hauv cov ntshav yuav txo qis tom qab siv cov khoom noj uas muaj carbohydrate. Raws li qhov tshwm sim, koj lub cev tau txais tsawg dua calories, uas yuav ua rau koj poob phaus.

Rau avid qab zib hniav

Nws yog pawg no ntawm cov neeg uas feem ntau sim ua rau cov nyhuv ntawm cov tshuaj ntawd rau lawv tus kheej. Nyob rau hauv txhua rooj plaub, qhov no yog pov thawj los ntawm kev txheeb xyuas. "Acarbose" rau kom poob phaus zoo li haum. Tam sim no koj tuaj yeem tsis ceev txoj kev suav lub carb. Txaus siab rau cov zaub mov koj nyiam uas tsis muaj kev ntshai ntawm nrhiav qhov dav ntxiv ntawm koj lub duav thiab lub duav.

Tib lub sijhawm, ntau tus neeg yuav muaj lus nug: lub cev yuav ua li cas yam tsis muaj carbohydrates? Txawm hais tias rau tus neeg noj qab haus huv, qhov no yog fraught nrog cov teeb meem loj, thiab yog tias peb tham txog cov neeg mob ntshav qab zib mellitus, lawv tuaj yeem poob rau hauv lub cev tsis xeev plab los ntawm kev tshaib plab. Cov neeg tsim khoom tshaj tawm tias qhov ua kom lub ntsej muag tsis zoo ntawm qhov tshuaj muaj tsawg. Qhov ntawd yog, nws tsis tuaj yeem txo cov ntshav qab zib kom qis dua ib qib tseem ceeb.

Thawj qhov kev tshoov siab

Tam sim no cia saib seb lub cuab yeej no ua haujlwm li cas. Nws cov khoom muaj txiaj ntsig yog li hauv qab no:

Cov tshuaj yuav luag txhua qhov txwv tsis pub qhov nqus ntawm cov khoom noj carbohydrates, tsuas yog zam ntawm ib qho me me ntawm lawv. Raws li qhov tseeb, qhov hnyav pib poob sai sai. Nws hais txog tib yam li yog koj muab cov qab zib, khob cij, yob thiab ncuav pastries.
Txoj kev no tsis cuam tshuam rau cov leeg nqaij, vim tias cov protein ntau rau hauv lub cev nqus tau yam tsis muaj teeb meem.
Cov tshuaj txo cov kev qab los noj mov, yog li cov txheej txheem ntawm kev poob phaus yuav yooj yim dua.

Nws yuav tsum raug sau tseg tias tsis tsuas yog "Acarbose", tab sis kuj tseem siv lwm cov tshuaj hypoglycemic muaj ib qho kev mob tshwm sim. Muaj ntshav qab zib, cov neeg mob txo qis lawv cov khoom qab zib, ncuav pastries thiab khob cij, yog li tsis muaj teeb meem ntawm kev noj tshuaj. Tab sis ib tus neeg dog dig tsis paub txog cov kev cai no thiab tseem muaj noj tshais nrog dej qab zib nrog mis nyuj, yob lossis ncuav qab zib. Yuav muaj dab tsi tshwm sim? Nyob rau hauv cov hnyuv muaj qhov tshaj ntawm cov carbohydrates, tsis muaj ib yam dab tsi rau lawv zom, mob plab zom mov, mob thiab yaum kom tso zis tso quav. Tsis xav ua qhov kev xav zoo li no? Zam qhov chaw ntawm carbohydrates, tshwj tsis yog rau tag nrho cov cereal hom cawv. Tom qab ntawd cov tshuaj hypoglycemic tsis tas yuav. Cov nyhuv yuav tuaj nws tus kheej.

Cov no yog cov lus qhia los ntawm feem ntau cov kws kho mob, khoom noj khoom haus thiab endocrinologist. Tsis thas noj cov tshuaj uas raug pom meej meej rau lwm lub hom phiaj. Tab sis, qhov tseeb tiag, cov poj niam muaj mob hnyav heev. Thiab yog tias koj txiav txim siab siv "Acarbose" / analogues ntawm cov tshuaj no, lawv yuav tsis tsum. Zoo, kev zoo nkauj yuav tsum muaj kev txi. Tab sis puas yog cov neeg raug tsim txom hauv cov lus hais nrov? Koj yuav tsum xav txog qhov yuav tshwm ntawm qhov kev ntxaws ntawd.

Yam koj yuav tsum paub

Feem ntau, tus neeg mob tsis tas yuav kawm cov tshuaj sib xyaw thiab xaiv qhov ntau npaum li cas, yog tias tus kws kho mob tau muab lus pom zoo thiab muab cov tshuaj ntau npaum li cas. Tab sis yog tias koj txiav txim siab coj nws tus kheej, nco ntsoov nyeem cov lus qhia rau kev siv. "Acarbose" yog siv rau cov ntshav qab zib hom 2 nrog kev tsis muaj txiaj ntsig ntawm kev noj zaub mov noj. Ntxiv mus, lub caij nyoog kawg yuav tsum yog tsawg kawg 6 lub hlis. Tus neeg sawv cev kuj tseem raug kho ua ib feem ntawm txoj kev kho rau cov ntshav qab zib hom 1.

Sab sij huam

Qhov no yog qhov mob siab, vim hais tias daim ntawv teev "cov kev mob tshwm sim" yog qhov zoo nkauj heev. Tab sis feem ntau cov tshuaj aspirin tuaj yeem nyuaj hu ua kev nyab xeeb tag nrho. Cov kev mob tshwm sim nram qab no yog teev nyob rau hauv cov lus qhia:

Mob vascular ntshaus
Kev ua xua tsis haum.
Teeb meem hauv lub zom zaub mov. Uas yog flatulence, raws plab, xeev siab.
Kev tawm tsam los ntawm daim siab. Cov no tuaj yeem yog kev yoog me uas tsis cuam tshuam rau kev nyob zoo. Tab sis nws kuj tseem ua tau qhov kev loj hlob ntawm jaundice.

Nws yuav muaj txiaj ntsig kom paub qhov zoo ntawm koj tus kheej nrog kev tshuaj xyuas ntawm kev noj tshuaj. "Acarbose" rau kom poob phaus yog siv, txawm hais tias tag nrho cov lus ceeb toom ntawm kev noj haus. Qhov tseeb, muaj ntau tus neeg uas tsis tau ntsib kev mob tshwm sim thiab tau txaus siab rau cov nyhuv ntawm cov tshuaj. Qee qhov kev txheeb xyuas hu nws ntau dua rau lub cev dua Xenical, uas tseem muaj peev xwm ua rau muaj kev hnov mob heev, tshwj xeeb, yog tias ib qho yog fond ntawm cov khoom noj muaj roj.

Cov kev siv tswv yim

Qhov feem ntau tshwm sim, raws li hauv cov lus qhia, kev tsis zoo yog qhov muaj teeb meem ntawm txoj hnyuv plab. Tab sis muaj cov tib neeg tsis txaj muag ntau leej uas txiav txim siab los sim cov txiaj ntsig ntawm txuj ci tseem ceeb kho rau lawv tus kheej. Ntawm tus nqi "Acarbose" muaj nyob, qhov no yog lwm qhov laj thawj sim cov tshuaj no. Yog li ntawd, rau qee qhov poob phaus txhua yam yog qhov zoo uas lawv coj nws mus rau ob peb lub hlis sib law liag, tib lub sijhawm zoo siab lawv tus kheej nrog khoom qab zib thiab poob ob peb phaus. Hmoov tsis zoo, tsis yog txhua tus muaj hmoo.

Nws yuav tsum tau nco ntsoov hais tias nws yog kev sim litmus tiag, uas qhia tau tias ntau dhau los ntawm kev noj zaub mov carbohydrates. Tab sis nws yog li ntawd, thiab nyob rau hnub tom ntej tib neeg ntseeg txog qhov no. Yog tias cov khoom noj sib xyaw ua kom sib npaug, ces tsis muaj qhov tsis xis nyob.

Ib qho kev zam yuav suav tau tias yog zawv plab lossis xeev siab hauv thawj 2-3 hnub ntawm kev noj tshuaj. Tab sis nws tsim nyog nce qab zib, zoo li "tsov rog" pib hauv plab. Kev nkag siab, txiav txim los ntawm kev tshuaj xyuas cov neeg txom nyem, yog qhov tsis zoo: mob, twists, txiav, rumbles thiab rages.

Txoj kev tawm

Peb twb tau kuaj xyuas cov txheej txheem ntawm kev ua ntawm Acarbose. Cov roj carbohydrates txuam nrog hauv txoj hnyuv, vim tias lawv tsis tuaj yeem sib cais thiab tsis tuaj. Muaj lawv roam, uas ua rau kom raug txim. Yog li ntawd, peb tuaj yeem hais tias qhov tshuaj no kuj muaj kev kawm ua haujlwm. Nws qhia koj kom noj khoom qab zib nkaus xwb hauv tsev thiab hnub so. Qhov no hauv nws tus kheej yog qhov zoo. Thiab yog tias nws pib "nrawm", tom qab ntawd peb tshem txhua cov carbohydrates, nrog rau khob cij thiab cereals, rau 4-6 teev - thiab txhua yam dhau. Yog li cov neeg sau hauv lawv kev tshuaj xyuas. Tab sis, nws puas tsim nyog poob txoj kev hnyav hauv txoj kev no? Qhov kev ntxhov siab hauv lub cev qee zaum tuaj yeem tsis ua txawv.

Tus txheej txheem ntawm kev ua thiab cov lus qhia rau kev siv Acarbose Glucobay

Tau ntau xyoo tsis muaj kev vam meej nrog DIABETES?

Lub taub hau ntawm lub koom haum: “Koj yuav xav tsis thoob tias yoojyim kho mob ntshav qab zib li cas los ntawm kev noj tshuaj txhua hnub.

Vim tias ntev ua tsis txaus ntawm cov tshuaj insulin, qhov mob hnyav ntawm cov endocrine tsim muaj nyob rau hauv lub cev - mob ntshav qab zib mellitus.

Qhov muaj peev xwm ntawm cov neeg uas muaj tus kab mob no tau txais kev txhawb nqa los ntawm cov tshuaj hypoglycemic uas tswj cov ntshav qabzib. Acarbose yog ib qho tshuaj tiv thaiv zoo rau kev kho mob ntshav qab zib.

Cov lus qhia rau kev teem caij

Cov tshuaj yog kws kho mob ntawm tus endocrinologist yog tias muaj cov tshuaj hauv qab no:

yam 2 mob ntshav qab zib,
ntau cov ntsiab lus nyob rau hauv cov ntshav thiab cov ntaub so ntswg ntawm cov kab mob lactic acid (mob ntshav qab zib ua rau tsis nco qab).

Tsis tas li ntawd, hauv kev sib xyaw nrog kev noj zaub mov, cov tshuaj tau qhia rau hom 1 ntshav qab zib mellitus.

Kev siv cov tshuaj tsis tsim nyog yog tias tus neeg mob muaj cov tshuaj hauv qab no:

tus kheej intolerance,
mob hnyav rau ntshav qab zib (ntshav qab zib ketoacidosis lossis DKA),
kev mob tsis ua hauj lwm ntawm lub siab nqaij (mob ntsws),
kev zom zaub mov nyuaj thiab mob (dyspepsia) ntawm qhov muaj mob ntev,
reflex ua haujlwm hloov plawv plawv uas tshwm sim tom qab noj mov (Remkheld's syndrome),
lub sijhawm uas xeeb tub thiab pub niam mis,
kev siv roj ntxiv hauv cov hnyuv,
ntev ua mob rau cov kab mob ntawm lub caj pas ntawm txoj hnyuv (ulcerative colitis),
protrusion ntawm plab plab hauv qab daim tawv nqaij (ventral hernia).

Txoj kev sib xyaw thiab cov tshuab ntawm kev txiav txim

Acarbose (Latin lub npe Acarbosum) yog polymeric carbohydrate muaj qhov me me ntawm cov suab thaj yooj yim, yooj yim soluble hauv kua.

Cov tshuaj yog sib txuas los ntawm kev ua biochemical nyob rau hauv kev cuam tshuam ntawm enzymes. Cov khoom siv raw yog Actinoplanes utahensis.

Acarbose hydrolyzes polymeric carbohydrates los ntawm inhibiting qhov cov tshuaj tiv thaiv enzyme. Yog li, qib kev tsim thiab lub zog nqus cov suab thaj hauv cov hnyuv yog txo.

Qhov no pab tswj cov ntshav ntshav qabzib. Cov tshuaj tsis ua kom txoj kev tsim khoom thiab tso zis ntawm cov tshuaj insulin los ntawm tus txiav thiab tsis pub ua kom cov ntshav qab zib tsawg. Cov tshuaj tsis tu ncua txo txoj kev pheej hmoo ntawm kev tsim mob plawv, thiab cov ntshav qab zib mob zuj zus.

Qhov nqus ntawm cov khoom nqus (nqus tau) tsis ntau dua li 35%. Qhov kev nkag siab ntawm ib yam khoom hauv lub cev tshwm sim hauv theem: thawj qhov kev nqus tau tshwm sim hauv ib thiab ib nrab sijhawm, theem nrab (kev nqus ntawm cov khoom lag luam metabolic) - nyob rau thaj tsam li ntawm 14 teev rau ib hnub.

Nrog rau kev ua kom tiav ntawm kev ua haujlwm tsis zoo rau lub raum (lub raum tsis ua haujlwm), qhov kev cia siab ntawm cov tshuaj yeeb tshuaj nce ntxiv tsib zaug, hauv cov neeg muaj hnub nyoog 60+ - 1.5 npaug.

Cov tshuaj yog tshem tawm los ntawm lub cev los ntawm txoj hnyuv thiab lub chaw tso zis. Lub sijhawm nruab nrab ntawm cov txheej txheem no tuaj yeem txog 10-12 teev.

Cov lus qhia rau kev siv

Kev siv cov acarbose cuam tshuam txog kev kho mob ntev ntev. Cov ntsiav tshuaj yuav tsum quag cawv tsawg kawg ntawm ib hlis twg ntawm ib teev ua ntej noj mov.

Hauv thawj lub sijhawm ntawm kev kho mob, 50 mg ntawm cov tshuaj yog kws kho peb zaug hauv ib hnub. Thaum tsis muaj qhov tshwm sim tsis zoo, lub koob tshuaj tau nce 2-4 zaug nrog ntu ncua 1-2 hli.

Qhov siab tshaj plaws ntau npaum li cas yog 200 mg, ib hnub - 600 mg.

Txog ntawm lub hom phiaj prophylactic, cov tshuaj tau tshwm sim hauv qhov tsawg kawg kiag (50 mg) ib hnub ib zaug. Raws li qhov ntsuas, qhov tsuas tshuaj tuaj yeem yog ob npaug.

Tau Acarbose Glucobai tuaj yeem siv rau qhov poob phaus?

Cov tshuaj feem ntau ua rau lub hauv paus ntawm Acarbose yog German tshuaj Glucobay. Nws cov nyhuv pharmacological, kev taw qhia thiab sib kis rau kev siv yog zoo ib yam rau Acarbose. Txawm li cas los xij, kev siv cov tshuaj tsis txwv rau kev kho mob ntshav qab zib.

Glyukobay yog nrov heev ntawm cov kws ncaws pob thiab cov neeg uas muaj kev sib ceg nrog cov rog dhau los. Qhov no yog vim qhov tseem ceeb ntawm cov tshuaj - lub peev xwm los tiv thaiv qhov tsim thiab nqus ntawm cov piam thaj. Qhov ua kom yuag dhau heev lawm, raws li txoj cai, yog cov khoom noj carbohydrates ntau dhau heev lawm. Tib lub sijhawm, carbohydrates yog qhov khoom tseem ceeb ntawm lub zog ntawm lub cev.

Thaum sib cuam tshuam nrog cov plab hnyuv plab zom mov, cov khoom noj khoom haus yooj yim carbohydrates yog nqus tau tam sim ntawd los ntawm txoj hnyuv, cov kev ua kom thoob tsib mus txog theem ntawm kev decomposition rau hauv cov yooj yim. Tom qab kev nqus tau tshwm sim, lub cev nrhiav kev nqus cov tshuaj thiab teeb lawv ntawm "hauv kev cia". Txhawm rau tiv thaiv cov txheej txheem no, cov neeg uas xav kom poob ceeb thawj coj Glucobai ua tus saib xyuas los ntawm cov carbohydrate.

Video khoom siv txog cov tshuaj carbohydrate-thaiv cov hlab:

Qhov tshwm sim, noj ntau dhau thiab cov lus qhia tshwj xeeb

Cov kev xav tsis zoo thaum lub sijhawm tswj hwm ntawm cov tshuaj tshwm sim feem ntau los ntawm daim tawv nqaij thiab txoj hnyuv huam.

Cov no suav nrog:

flatulence
chim quav
mob plab zom mov (dyspepsia),
nyuaj txhawb cov ntsiab lus ntawm cov hnyuv (hnyuv tawm tsam),
siab bilirubin qib (daj)
daim tawv liab ua pob los ntawm cov hlab ntshav (erythema),
cov ua xua ntawm caj ces.

Tshaj cov tshuaj noj tau yog pom los ntawm kev mob plab hnyuv, nce roj ntxiv, raws plab. Kev nyem ntawm tus mob no yog mob, ntxiv rau kev tshem tawm cov zaub mov carbohydrate los ntawm cov khoom noj.

Acarbose yog ntawv ceeb toom rau kev ceev faj rau cov neeg mob uas kis kab mob, nrog rau cov neeg muaj hnub nyoog qis dua 18 xyoo.

Thaum kho cov tshuaj, cov mob tseem ceeb yog:

tom qab noj zaub mov nruj
kev soj ntsuam tas mus li ntawm hemoglobin, transaminases thiab qab zib (ntshav suav).

Hauv cov zaub mov, sucrose yuav tsum tau hloov nrog piam thaj.

Analogues ntawm cov tshuaj

Cov tshuaj uas muaj cov nyhuv zoo sib xws muaj acarbose yog cov tshuaj tseem ceeb.

Ob yam tshuaj yog siv los hloov chaw:

Glucobay50 thiab 100 mg ntsiav tshuaj daim ntawvBAYER PHARMA, AG (Lub Tebchaws Yelemees) Alumina100 mg ntsiav tshuaj“Abdi Ibrahim Ilach Sanay thiab Tijaret A.Sh.” (Qaib ntxhw)

Tus neeg mob lub tswv yim

Los ntawm kev tshuaj xyuas cov neeg mob, nws tuaj yeem xaus lus tias Acarbose ua haujlwm zoo rau kev tswj cov ntshav qab zib kom tsawg, tab sis nws txoj kev tswj hwm feem ntau nrog cov kev mob tshwm sim tsis zoo, yog li nws qhov kev siv yog impractical los txo qhov hnyav.

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Cov tshuaj tau muab tshuaj yog cov kws kho mob sau thiab ua nruj raws li cov lus qhia. Ib qho ntxiv, Kuv noj 4 mg ntawm NovoNorm thaum noj su. Nrog kev pab ntawm ob lub tshuaj, nws yog ib qho ua tau kom cia qab zib nyob rau yav tav su. Acarbose "quenches" qhov cuam tshuam ntawm cov nyom hnyav, kuv qhov ntsuas ob teev tom qab noj yog 6.5-7.5 mmol / L. Sij hawm dhau los, qis dua 9-10 mmol / L tsis yog. Cov tshuaj ua haujlwm zoo tiag tiag.

Kuv muaj ntshav qab zib hom 2. Tus kws kho mob pom zoo Glucobai. Cov ntsiav tshuaj tsis tso cai rau cov piam thaj yuav nqus mus rau txoj hnyuv, vim li ntawd, cov suab thaj “tsis dhia”. Hauv kuv qhov teeb meem, cov tshuaj normalized qab zib rau cov cim tsawg heev rau cov ntshav qab zib.

Kuv sim Glucobai yog txhais tau tias yuav txo qhov hnyav. Tsim txom cov kev mob tshwm sim. Mob raws plab tsis tu ncua, ntxiv rau qaug zog. Yog tias koj tsis mob ntshav qab zib, tsis nco qab txog cov tshuaj no thiab poob phaus nrog kev pab cuam ntawm pluas noj thiab ua kom lub cev.

Cov tshuaj yog ntawv yuav tshuaj. Tus nqi ntawm Glucobai ntsiav tshuaj yog txog 560 rubles rau 30 daim, nrog muab tshuaj ntawm 100 mg.

Tshiab Tsim Tshuaj Hom 2 Tshuaj Ntshav Qab Zib

Tus neeg mob uas tau raug tshuaj kho rau hom 2 mob ntshav qab zib mellitus, cov tshuaj tau xaiv hauv kev sib xyaw. Lawv txoj kev txais tos feem ntau yuav tsis nres ib sim neej. Yog lawm, kev noj haus yog muab suav ua ntej. Thiab tsuas yog tom qab ntawd, yog tias qhov kev xav tau tshwm sim, yog kev kho nrog kev siv tshuaj. Qhov no tuaj yeem piav qhia los ntawm qhov tseeb tias ua tsaug rau khoom noj khoom haus, ntshav qabzib yuav tuaj yeem nyob ib txwm. Yog li tsis tas yuav muaj kev npaj tshuaj insulin. Nws tshwm sim thaum lub pathology pib sib zog.

Cov yam ntxwv ntawm kev siv tshuaj

Tus kab mob yog pom los ntawm kev nthuav dav zuj zus. Thaum pib, nws cov tsos mob tau hais tawm tsis muaj zog. Yog li ntawd, hmoov tsis, ntau tus tig mus rau kws kho mob thaum muaj teeb meem. Yog hais tias tus kab mob tsis quav ntsej tau ntev, qhov ua kom tsis meej tuaj yeem nrawm dua.

Lub hauv paus ntawm kev kho ntshav qab zib yog kev siv tshuaj kho mob. Cov tshuaj ntshav qab zib tuaj nyob hauv ntau pab pawg.

Txoj kev kho yuav tsum:

Ua kom muaj zog insulin ntau lawm.
Ua kom cov nqaij mos rhiab ua rau cov tshuaj hormones.
Txwv tsis pub qhov nqus ntawm cov piam thaj thiab txo cov gluconeogenesis, uas yog, nws cov lus coj ua.
Kho cov ntshav lipid feem.

Hauv ntej, nrog kev pabcuam ntawm kev kho yuav tsum tsim kom muaj kev tswj hwm ntev ntev thiab tiv thaiv kom tsis txhob muaj teeb meem.

Cov pab pawg tseem ceeb ntawm cov tshuaj rau ntshav qab zib hom 2 muaj:

Cov tshuaj noj, vim tias, cov txiav ua ke tsim cov tshuaj insulin zoo dua. Peb tab tom tham txog sulfonylurea kev npaj uas muaj cov qauv zoo sib xws hauv cov chemical thiab sib txawv los ntawm ib tiam. Tsis ntev los no, cov tshuaj tshiab, Novonorm thiab Starlix, kuj tau tshwm sim.
Biguanides, lub hom phiaj ntawm uas yog txhawm rau kom nce qib kev pheej hmoo ntawm tes rau qhov hormone. Qhov ob nto moo tshaj plaws yog raws li metformin (Siofor, Glucofage). Lawv tau sau tseg rau cov neeg rog, vim lawv pab txhawb nws kom txo.
Alpha glucosidase inhibitors. Ua rau cov piam thaj nqus qis. Feem ntau siv tshuaj "Glucobay."
Rhiab neeg (ua neeg muaj zog). Ua tsaug rau lawv, lub teb ntawm cov ntaub so ntswg rau cov tshuaj hormones ntau ntxiv. Raug rau cell receptors yog feem ntau ua tiav siv Actos.

Hauv ib pab pawg sib cais muaj cov tshuaj tiv thaiv ntshav kho mob ntshav qab zib hom 2. Lawv yuav tsum tau, thaum muaj teeb meem ntawm lub cev vascular. Ntshav siab feem ntau tswj hwm los ntawm thiazide diuretics, thiab ntxiv rau cov calcium calcium blockers (calcium antagonists).

Cov tshuaj insulin rhiab heev

Ntawm cov tshuaj, thiazolidinediones thiab biguanides yuav tsum tau txawv. Txhua pawg tau nws tus kheej zoo.

Cov tshuaj mob ntshav qab zib hom 2, xws li thiazolidinediones, siv rau:

txo txoj kev pheej hmoo ntawm exacerbating tshwm sim teeb meem nrog cov hlab ntsha,
qab zib stabilization,
pancreatic beta hlwb
tiv thaiv thiab kho mob lub hom phiaj.

Hmoov tsis zoo, lawv kuj muaj qhov tsis zoo.

Kev kho mob Thiazolidinedione tuaj yeem ua rau:

cov tsos ntawm phaus ntxiv,
o ntawm qis qis dua,
txha txha caj qaum.

Yuav kom ua tiav qhov txiaj ntsig ntau dua los sis tsawg dua, cov nyiaj yuav tsum siv sijhawm ntev. Tsis tas li ntawd, muaj kev txwv rau lawv kev siv.

Cov npe ntawm cov neeg mob uas txwv tsis pub siv cov tshuaj no suav nrog cov pojniam xeebtub thiab cov neeg muaj menyuam mos, nrog rau cov neeg muaj mob los ntawm:

mob siab mob hlwb,
lub plawv tsis ua hauj lwm
mob plawv plawv.

Koj tsis tuaj yeem ua ke ib qho insulin thiab thiazolidinediones.

Ib qho txiaj ntsig zoo kho tau zoo kuj pom los ntawm kev siv cov khoom loj.

muaj kev txhim kho nyob rau hauv cov ntshav muaj pes tsawg leeg, thaum tus nqi ntawm cov cholesterol raug txo qis,
hypoglycemia ploj,
txoj kev pheej hmoo ntawm lub plawv nres hauv cov neeg mob kev txom nyem los ntawm qhov hnyav tshaj yog txo kom tsawg.

Biguanides tsis ua rau kev rog. Txawm hais tias, thaum siv lawv, tus neeg mob yws yws vim muaj kev tsis xis nyob hauv txoj hnyuv plab.

daim siab ua hauj lwm
haus cawv
coj menyuam.

Cov kws kho mob nyiam siv cov tshuaj hauv qab no rau kev kho mob: Siofor, Glyukofazh, Metfogamma.

Tshuaj tua hluav taws xob

Cov kev txiav txim siab ua haujlwm yog qhib kom ua tiav nrog kev pab ntawm sulfonylurea derivatives thiab meglitinides. Qhov kev xaiv thawj yog cov tshuaj, cov nyhuv ntawm tau hnov zoo li yuav luag tam sim ntawd. Ua tsaug rau lawv, cov teeb meem vascular tshwm sim tsawg dua. Feem ntau tshuaj yog "Diabeton MV", "Maninil." Hauv qee kis, kev kho mob nrog sulfonylurea derivatives yog txwv tsis pub.

cov neeg mob raum tsis ua haujlwm lossis ketoacidosis,
xeeb tub
pub niam mis.

Txawm hais tias cov tshuaj muab tau cov txiaj ntsig sai, nws muaj peev xwm:

ntshav qab zib,
kev txhim kho tiv taus
thawj.

Raws li rau meglitinides, lawv tuaj yeem siv los ua kom cov suab thaj nyob hauv theem. Lawv kuj muaj cov nyhuv sai. Feem ntau, NovoNorm thiab Starlix yog koomhaum.

Qhov tsis zoo yog tseem muaj. Firstly, lub cev hnyav tuaj yeem nce ntxiv. Thib ob, nws tseem tsis tau muaj pov thawj tias nrog kev siv lub sijhawm ntev, cov hauj lwm zoo ntawm meglitinides tseem nyob.

Txhua yam ntawm cov tshuaj hais los saum toj no tuaj yeem ua rau muaj mob plawv, mob nkees thiab glycemic coma. Yog li no, nyob rau xyoo tas los no, feem ntau cov kws kho mob tsis kam lees cov nyiaj no, hloov lawv nrog cov tshuaj tshiab.

Siofor thiab Glyukofazh

Rau cov mob ntshav qab zib, cov tshuaj no yog ua raws metformin. Yog tias kev kuaj pom tus mob ntshav qab zib hom 2 tshwm sim thaum ntxov, yog tias tus neeg mob noj cov zaub mov muaj protein tsawg, thiab nws yuav noj tshuaj metformin tsis tu ncua, ces cov tshuaj ntxiv thiab kev txhaj tshuaj hormone yuav tsis tsim nyog.

"Siofor" yog qhia tsis yog rau cov neeg mob ntshav qab zib, tab sis kuj rau txhua tus neeg uas muaj kev cuam tshuam ntawm systolic thiab diastolic siab. Cov tshuaj pab ua rau lub cev poj niam rov qab ua dua qub thiab rov ua haujlwm rov muaj me nyuam.

Cov neeg mob tom qab 65, nrog rau cov neeg uas tau ntsib nrog lub cev ntau dhau ib hnub dhau ib hnub, yuav tsum tau muab cov tshuaj Siofor ua tib zoo (lactic acidosis, uas yog nrog los ntawm kev nce ntxiv hauv acidity, tsis yog txiav txim tawm).

Txhawm rau txhim kho qhov kev ua ntawm Siofor, endocrinologist pom zoo kom siv cov tshuaj tshiab - glucagon-zoo li peptide-1 receptor agonists (GLP-1) thiab dipeptyl peptidase-4 (DPP-4) inhibitors.

Hauv thawj qhov xwm txheej, nws yog tshuaj uas muaj cov tshuaj hormones uas ua rau tsis qab los noj mov thiab txhawb kev tsim cov tshuaj insulin. Muaj cov qauv hauv cov xaum xim. Kev txhaj tshuaj yuav tsum tau ua ib teev ua ntej noj mov. Ib qho txheej txheem muaj txaus ib hnub.

Qhov kev xaiv thib ob yog hom tshuaj uas muaj enzyme uas ua rau puas tsuaj ntawm GLP-1. Cov koob tshuaj pom zoo yog 1 ntsiav tshuaj thawm hnub.

Cov yam ntxwv zoo ntawm "Glucophage":

Txo kev nqus ntawm carbohydrates nyob rau hauv lub plab zom mov.
Txo cov kua nplaum tawm los ntawm nplooj siab.
Ua rau insulin rhiab heev.
Txhim kho txoj kev ua los ntawm kev ua kom muaj suab thaj los ntawm lub hlwb.

Ntawm qee tus neeg mob tsawg tsawg los ntawm kev noj cov tshuaj metformin, qhov tsis zoo yog ua tau rau hauv daim ntawv ntawm:

xeev siab
nws yog xim hlau saj hauv lub qhov ncauj kab noj hniav,

ntuav,
hnyuv colic
ntev mus tsub zuj zuj ntawm cov roj nyob hauv cov hnyuv,
zawv plab.

Txhawm rau kom tsis txhob muaj qhov tshwm sim, cov tshuaj ua haujlwm ntev tau tsim rau hom 2 mob ntshav qab zib mellitus, uas tsis ua rau muaj kev mob tshwm sim. Nws yog hais txog Glucofage Ntev.

Cov tshuaj ntsiav tau noj ib hnub ib zaug. Raws li qhov tshwm sim, metformin yog xa tawm maj thiab ntev ntev. Nws tsis muaj qhov pib spasmodic nyob rau hauv cov tshuaj muaj zog.

Nws yuav tsum tau hais cais txog cov teeb meem uas ob Siofor thiab Glucophage yog contraindicated.

Txhawm rau tsis kam kho nrog cov neeg sawv cev no yog qhov tsim nyog thaum:

Cov hlwv tsis ua haujlwm zoo li mob hepatic.
Hypoxia ntawm cov hlab plawv hlab ntsws lossis ua pa.
Lub plawv nres, angina pectoris, mob plawv dhia tsis xwm yeem.
Teeb meem nrog lub hlwb ncig.
Nyuaj siab thiab ntxhov siab.
Kev kis mob hnyav.

Kev raug mob.
Kev tiv thaiv ntawm cov hlau thiab folic acid.
Kev quav cawv.
Cev xeeb tub

Nyob rau lub sijhawm tomqab kawg, cov tshuaj no tseem raug txwv.

Nyiaj txiag tag

Feem ntau, rau kev mob ntshav qab zib hom 2, kev kho yog muab nrog ib cov tshuaj. Tab sis thaum txoj kev kho mob tsis coj qhov tshwm sim xav tau, nws yog ib qho tsim nyog yuav tsum tau siv lwm yam tshuaj ntxiv. Feem ntau, cov tshuaj xaiv tsis tuaj yeem daws txhua yam teeb meem tshwm sim. Yog li, nws hloov los ntawm tus neeg sawv cev sib xyaw ua ke.

Koj tuaj yeem kho nrog cov tshuaj zoo li no yam tsis muaj kev phom sij ntawm kev phiv. Feem ntau, cov kws kho mob siv rau kev sib txuas ntawm thiazolidinediones thiab metformin, zoo li sulfonylurea derivatives thiab tib yam metformin.

Cov tshuaj sib xyaw ntshav qab zib yog tsim los tiv thaiv kev txhim kho txuas ntxiv ntawm hyperinsulinemia. Vim li ntawd, qhov xav tau rau kev kho mob insulin ploj mus.

Cov tshuaj kho nrov yog Glibomet. Nws yog qhov tsim nyog thaum kev kho tsis tau ua tiav.

Txawm li cas los xij, Glibomet yuav tsum tau muab pov tseg yog tias muaj:

muaj teeb meem nrog kev ua haujlwm ntawm daim siab,
lub raum tsis ua hauj lwm.

Lwm yam tshuaj yog xaiv rau cov poj niam cev xeeb tub thiab pub mis.

"Glibomet" qee zaum ua rau muaj kev phiv nyob rau hauv daim ntawv ntawm:

tso quav tsis taus
xeev siab
kiv taub hau
tawv nqaij ua pob thiab khaus.

Cov tshuaj yuav tsum tau coj nruj me ntsis raws li cov lus qhia tshwj xeeb.

Ntshav Qab Zib Nyiam Siv Tshuaj Kho Mob

Yog tias tus neeg mob xav tau kev kho mob ntshav qab zib hom 2, nws tuaj yeem tau txais kev kho mob siab. Muaj ib daim ntawv tshwj xeeb uas teev txhua tus nqi tshwj xeeb uas tau muab tshuaj rau cov neeg mob txhua lub hlis thaum muaj xwm txheej ceev.

Tus mob ntshav qab zib tuaj yeem xav kom tau txais:

qee cov tshuaj - Acarbose, Glycvidon, Glibenclamide, Glucofage, Metformin, Gliclazide, Glimepiride, Rosiglitazone, Repaglinide,
tshuaj insulin rau kev txhaj tshuaj,
"Isofan-insulin" nyob rau hauv daim ntawv ntawm ncua kev kawm,
100 g ntawm ethyl cawv,
insulin koob txhaj tshuaj thiab koob.

Thaum tus neeg mob xav tau kev noj qab haus huv, nws tau muab ib qho glucometer, nrog rau cov khoom siv sib thooj, kom ntsuas peb zaug nyob rau ib hnub. Cov nyiaj muab tshaj tawm tus nqi txo tus nqi. Yog tias tsis tas yuav tshuaj insulin, ces nws yog qhov tsim nyog yuav tau ua kom zoo dua li qhov ntsuas tshwj xeeb. Koj tuaj yeem siv ib daim hlab ib hnub. Yog tias muaj teeb meem tsis pom kev zoo, cov neeg mob tau pub dawb ntawm lub ntsej muag, thiab cov ntaub ntawv uas tso cai rau kev tshuaj ntsuam ib hnub.

Yog tias koj ua tib zoo thiab nruj me ntsis ua raws cov lus pom zoo rau kev kho mob, siv cov tshuaj kho mob, ua raws li kev noj haus, tshem tawm cov khoom lag luam uas tsim kev puas tsuaj los ntawm cov ntawv qhia, qhov xwm txheej yuav tsim txoj hauv kev zoo tshaj plaws thiab hom 2 ntshav qab zib yuav raug tswj. Kev saib xyuas kev noj qab haus huv muaj lub neej tag nrho yam tsis muaj teeb meem txaus ntshai. Ua li no, koj tsuas yog xav kom tiv thaiv kom tsis txhob muaj piam thaj rau hauv qab zib.