Cov tshuaj Argosulfan: cov lus qhia rau kev siv > Kev khomob thiab kev tiv thaiv

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm 2% cream, uas sawv cev rau homogeneous loj ntawm dawb lossis dawb nrog lub tint los ntawm lub teeb grey rau liab.

Cov tshuaj nquag ntawm Argosulfan yog nyiaj sulfathiazole. 1 g ntawm cream muaj 20 mg ntawm lub nquag sib xyaw ua noj.

Cov neeg txais tshuaj ntawm cov tshuaj no:

Cetostearyl cawv - 84.125 mg,
Vaseline dawb - 75.9 mg,
Ua kua paraffin - 20 mg,
Glycerol - 53.3 mg,
Sodium lauryl sulfate - 10 mg,
Cov poov tshuaj dihydrogen phosphate - 1.178 mg,
Methylhydroxybenzoate - 0.66 mg,
Ntsev sodium hydrogen phosphate - 13,052 mg,
Propylhydroxybenzoate - 0.33 mg,
Dej d / i - txog 1 g.

Argosulfan qab zib muag tau muag hauv txhuas lub raj ntawm 15 lossis 40 g, ntim rau hauv cov thawv ntawv thawv ntawm 1 pc.

Kev ntsuas rau kev siv Argosulfan

Cov tshuaj yog tawm rau kev kub hnyiab ntawm txhua qib ntawm txhua qhov chiv keeb (suav nrog lub hnub ci, cua sov, hluav taws xob, hluav taws xob, tshuaj lom neeg), lub qhov txhab purulent, kev raug mob hauv tsev neeg me (kev ua xeb, txiav).

Kev siv cov tshuaj Argosulfan tau ua haujlwm zoo hauv kev mob rau qhov mob txhawm rau sab qis ntawm ntau yam etiologies, suav nrog obliterating endarteritis, erysipelas, mob txha mos tsis txaus, thiab mob hlab ntsha hauv ntshav qab zib mellitus.

Ntxiv rau, cov tshuaj nplaum yog siv rau cov tshuaj tiv thaiv frostbite, bedsores, microbial eczema, impetigo, streptostaphyloderma, sib cuag tau yooj yim thiab mob dermatitis.

Cov Yuav Tsum Muaj

Cov Lus Cog Tseg rau kev siv Argosulfan yog:

Lub sijhawm yug thiab menyuam yaus txog li ob lub hlis (vim tias qhov pheej hmoo ntawm kev txhim kho "nuclear" jaundice),
Kev tsis txaus yug lub cev ntawm enzyme qabzib-6-phosphate dehydrogenase,
Cov tshuaj tiv thaiv tsis haum rau cov nyiaj sulfathiazole thiab lwm yam sulfonamides.

Muab koob tshuaj thiab kev tswj hwm ntawm Argosulfan

Argosulfan qab zib yog npaj rau kev siv sab nraud. Nws tuaj yeem siv rau qhib cov tawv nqaij lossis siv cov khaub ncaws ua paug (hermetic). Cuam tshuam rau thaj tsam ntawm daim tawv nqaij yuav tsum tau ua ntej ntxuav, thiab tom qab ntawd thov cov qab zib hauv qab cov kab mob.

Nrog cov qhov txhab ntub (nrog rau kev tsim exudate) ua ntej siv Argosulfan, daim tawv nqaij tau kho nrog 3% aqueous tov ntawm boric acid los yog 0.1% daws ntawm chlorhexidine.

Cov tshuaj nplaum tau thov rau thaj chaw muaj kev tiv thaiv nrog txheej txheej 2-3 hli tuab kom txog thaum cov ntaub so ntswg raug kho kom zoo, thiab yog tias daim tawv nqaij txhuam cov tawv nqaij, kom txog rau thaum lub qhov txhab mob tau npaj rau kev phais. Thaum kho nrog Argosulfan, cov tshuaj nplaum yuav tsum npog tag nrho cov tawv nqaij puas.

Lub sijhawm sijhawm ntawm kev kho thiab qhov txhaj ntawm cov tshuaj tau txiav txim siab ntawm tus kheej hauv txhua kis.

Cov lus qhia rau Argosulfan tau hais tias cov tshuaj nplaum yuav tsum siv los ntawm 1 mus rau 3 zaug hauv ib hnub, thaum qhov siab tshaj plaws txhua hnub yuav tsum tsis pub tshaj 25 g. Lub sijhawm tiv thaiv ntev tshaj plaws ntawm kev kho mob yog 2 hli.

Qhov tshwm sim ntawm Argosulfan

Hauv cov xwm txheej cais, kev tsis haum rau daim tawv yog ua tau. Qee zaum ntawm qhov chaw ntawm daim ntawv thov ntawm lub lee, tawv nqaij yuav tshwm sim, ua kom pom los ntawm kev hnov mob hlawv.

Nrog rau kev siv lub sijhawm ntev heev ntawm Argosulfan, kev hloov pauv ntshav yog qhov ua tau, uas yog tus yam ntxwv ntawm txhua qhov systemon sulfonamides (agranulocytosis, mob leukopenia, thiab lwm yam), zoo li desquamative dermatitis.

Cov lus qhia tshwj xeeb

Kev saib xyuas yuav tsum tau ua thaum thov cov qab zib hauv cov neeg mob poob siab uas muaj kev kub nyhiab, vim tias tsis muaj txoj hauv kev los sau cov lus qhia txog kev tiv thaiv tsis haum.

Nrog rau kev kho mob ntev, cov ntshav ntshav, tshwj xeeb tshaj yog cov qib sulfatiazole, yuav tsum tau saib xyuas. Qhov no feem ntau txhawj xeeb cov neeg mob raum thiab mob siab.

Cov lus qhia rau Argosulfan hais tias nws tsis cuam tshuam rau lub peev xwm tsav tsheb thiab tuaj yeem siv rau hauv cov neeg mob uas cov kev ua ub no cuam tshuam nrog kev nce siab ntawm kev saib xyuas.

Cov qauv ntawm Argosulfan

Tsis muaj tag nrho cov analogues ntawm Argosulfan raws li cov nyiaj ntsev ntawm sulfathiazole. Lwm cov kab mob ntxiv, kab lus los yog tshuaj pleev ntawm sulfanilamide muaj pes tsawg leeg zoo li cov tshuaj no:

Arghedin (chaw tsim tshuaj paus Bosnalijek, Bosnia thiab Herzegovina), Dermazin (Lek, Slovenia) thiab Sulfargin (Tallinn Tshuaj Tsob Nroj, Estonia) yog cov tshuaj uas muaj cov khoom xyaw nquag yog nyiaj ntsev sulfadiazine. Lawv tau tsim nyob rau hauv ib lub raj ntawm 40, 50 g, ib yam li hauv hauv 250 g thawv. Lawv tau siv rau tib qhov taw qhia li Argosulfan. Ntxiv rau, cov sulfanamide no tawm tsam cov kab mob fungi ntawm cov genus Candida thiab dermatophytes, vim tias nws tuaj yeem kho tus mob candidiasis thiab lwm yam tawv nqaij mycoses,

Mafenide acetate tshuaj pleev 10% muaj nyob hauv ib pob ntawm 50 g hauv ib lub hwj. Cov tshuaj tseem muaj cov nyhuv antifungal tiv thaiv candida,

Cov tshuaj pleev Streptocide thiab cov tshuaj loog 5% thiab 10% muaj nyob rau hauv lub thawv ntawm 25 thiab 50 g. Cov lus qhia rau kev siv zoo ib yam li Argosulfan.

Cov chaw muag tshuaj

Argosulfan yog ib qho ntawm sab nraud tshuaj uas muaj cov nyhuv tshuaj tiv thaiv kab mob. Nws muab kev tiv thaiv zoo ntawm qhov mob ntawm qhov chaw los ntawm kev kis kab mob, txhawb qhov zoo ntawm trophic, hlawv thiab purulent txhab, txo lub sijhawm ntawm kev kho thiab lub sijhawm ntawm kev npaj ntawm lub qhov txhab rau hloov tawv nqaij. Feem ntau, pom muaj kev txhim kho, tshem tawm qhov xav tau kev hloov pauv.

Nosological kev faib tawm (ICD-10)

Cream rau kev siv sab nraud	1 g
yam tshuaj:
Nyiaj sulfathiazole	20 g
tus zam: cetostearyl cawv (methyl cawv - 60%, stearyl cawv - 40%) - 84.125 mg, kua paraffin - 20 mg, roj dawb petrolatum - 75,9 mg, glycerol - 53.3 mg, sodium lauryl sulfate - 10 mg, methyl parahydroxybenzoate - 0, 66 mg, propyl parahydroxybenzoate - 0.33 mg, potassium dihydrogen phosphate - 1.178 mg, sodium hydrogen phosphate - 13.052 mg, dej rau kev txhaj tshuaj - txog li 1 g

Cov Tshuaj Hauv Tshuaj

Argosulfan ® yog cov tshuaj tua kab mob siab tshaj plaws uas txhawb nqa cov qhov txhab ua kom mob zoo (suav nrog hlawv, trophic, purulent), muaj kev tiv thaiv zoo ntawm cov qhov txhab los ntawm kev kis tus kab mob, txo lub sijhawm kho thiab npaj lub sijhawm ntawm lub qhov txhab rau daim tawv nqaij hloov chaw, feem ntau ua rau kev txhim kho, tshem tawm qhov xav tau kev hloov pauv.

Sulfanilamide, ib cov nyiaj sulfathiazole, uas yog ib feem ntawm cov tshuaj nplaum, yog cov tshuaj tua kab mob ua kom yuag thiab muaj cov kab mob ntau yam ntawm cov kab mob bacteriostatic ua rau cov kab mob gram-positive thiab gram-negative. Tus txheej txheem ntawm antimicrobial nyhuv ntawm sulfathiazole - inhibition ntawm kev loj hlob thiab rov ua dua ntawm cov microbes - cuam tshuam nrog kev sib tw antagonism nrog PABA thiab kev cuam tshuam ntawm dihydropteroate synthetase, uas ua rau muaj kev cuam tshuam ntawm kev sib txuas ntawm dihydrofolic acid thiab, thaum kawg, nws nquag metabolite, tetrahydrofolic acid, tsim nyog rau kev sib txuas ntawm purines thiab pyroms.

Cov nyiaj ions muaj nyob rau hauv qhov kev npaj txhim kho cov nyhuv antibanial ntawm sulfanilamide - lawv inhibit kev loj hlob thiab faib cov kab mob los ntawm khi rau microbial cell DNA. Tsis tas li ntawd, ions nyiaj yuav ua rau tsis muaj zog ntawm cov khoom sulfonamide. Vim yog qhov tsawg kawg nkaus resorption ntawm cov tshuaj, nws tsis muaj kev phiv tshuaj lom.

Cov Tshuaj Pharmacokinetics

Cov nyiaj sulfathiazole uas muaj nyob hauv qhov kev npaj muaj cov solubility me me, qhov txiaj ntsig ntawm qhov ntawd, tom qab kev siv tshuaj pleev, kev saib xyuas ntawm cov tshuaj nquag hauv lub qhov txhab ntev tswj nyob rau tib theem. Tsuas yog ib qho nyiaj me me ntawm cov nyiaj sulfathiazole tshwm nyob rau hauv cov hlab ntshav, tom qab ntawd nws yauv ua tshuaj acetylation hauv lub siab. Hauv cov zis muaj nyob rau hauv daim ntawv tsis muaj zog metabolites thiab tsis hloov. Qhov nqus ntawm cov nyiaj sulfathiazole ntau ntxiv tom qab thov rau ntawm cov qhov txhab dav dav.

Kev ntsuas pom ntawm cov tshuaj Argosulfan ®

kub hnyiab ntawm ntau qib, ntawm ib qho xwm txheej (suav nrog cua sov, hnub ci, tshuaj lom neeg, hluav taws xob, hluav taws xob),

trophic mob rau sab ceg qis ntawm ntau yam hauv paus (nrog rau cov mob txha caj qaum tsis txaus, obliterating endarteritis, mob ntshav qab zib hauv ntshav qab zib mellitus, erysipelas),

kev raug mob hauv tsev neeg me (kev txiav, txhim kho),

cov kab mob dermatitis, mob impetigo, tiv thaiv yooj yim rau mob dermatitis, kab mob microbial,

Tsuas tshuaj thiab tswj hwm

Hauv zos ob qho tib si los ntawm txoj kev qhib qauv, thiab hauv kev hnav khaub ncaws occlusive.

Tom qab ntxuav thiab phais mob, cov tshuaj tau thov rau lub qhov txhab nrog txheej txheej 2-3 hli hauv kev ua raws li kev ua kom tsis taus mob 2-3 zaug hauv ib hnub. Lub qhov txhab thaum kho yuav tsum them nrog qab zib. Yog tias ib feem ntawm lub qhov txhab qhib, yuav tsum tau siv cov cream ntxiv. Ib qho kev hnav khaub ncaws sab nraud muaj peev xwm ua tau, tab sis tsis tas yuav tsum muaj.

Cov tshuaj pleev yog thov kom txog thaum lub qhov txhab raug kho kom zoo lossis mus txog rau thaum cov tawv nqaij hloov mus rau lwm qhov.

Yog tias cov tshuaj siv rau ntawm qhov mob txhab, exudate yuav tshwm sim.

Ua ntej thov cov qab zib, nws yog qhov yuav tsum ntxuav lub qhov txhab nrog 0.1% aqueous tov ntawm chlorhexidine lossis lwm yam antiseptic.

Qhov siab tshaj plaws niaj hnub noj yog 25 g. Qhov siab tshaj plaws ntawm kev kho mob yog 60 hnub.

Chaw tsim tshuaj paus

Kws tshuaj tsob nroj Elfa A.O. 58-500 Jelenia Gora, ul. B. Teb 21, Poland.

Tus tuav ntawm daim ntawv pov thawj rau npe: LLC "VALANTE". 115162, Russia, Moscow, ul. Shabolovka, 31, p. 5.

Kev thov cov neeg tau txais kev pabcuam yuav tsum raug xa mus rau LLC "VALANTE". 115162, Russia, Moscow, ul. Shabolovka, 31, p. 5.

Tel./fax: (495) 510-28-79.

Pharmacological kev txiav txim

Tshuaj pleev Argosulfan muaj cov nyhuv antimicrobial, ua rau muaj kev kho mob nrawm ntawm qhov txhab ntawm ntau yam etiologies (pur txhab txhab, trophic ulcerative hloov pauv, hlawv) Cov tshuaj ua rau mob hnyav ntxiv, tiv thaiv kev sib kis ntawm qhov txhab, txo lub sijhawm kho. Qee qhov xwm txheej, tawm tsam keeb kwm ntawm kev siv tshuaj, kev xav taukev sib hloov daim tawv nqaij flaps.

Argosulfan cream muaj ib qho ntawm sulfonamides - sulfathiazole, uas muaj lub suab hais txog kev ua haujlwm antimicrobial, ua yeeb yam rau cov kab mob me me bacteriostatically. Lub spectrum ntawm kev ua ntawm lub active tivthaiv yog gram-zoo microbes thiab gram-tsis zoo muaj. Lub tswv yim tseem ceeb ntawm cov tshuaj tua kab mob yog tsom rau kev txwv txoj kev rov ua dua tshiab thiab kev loj hlob ntawm cov kab mob me me los ntawm kev thaiv cov kev ua ntawm dihydroperoate synthetase thiab cov kev tawm tsam kev sib tw nrog PABA. Raws li qhov tshwm sim los ntawm cov tshuaj tiv thaiv, cov txheej txheem ntawm synthesizing dihydrofolic acid thiab nws lub ntsiab metabolite, tetrahydrofolic acid, uas yog qhov tseem ceeb rau cov tshuaj tiv thaiv, hloov pauv pyrimidines thiab purines microorganism.

Ua Tsaug Nyiaj ions antimicrobial nyhuv ntawm sulfonamide yog txhim kho los ntawm kev khi rau cov kab mob DNA thiab cov kev txwv tsis pub txuas ntxiv ntawm kev loj hlob thiab faib cov microbial cell. Tsis tas li ntawd, nyiaj ions cuam tshuam cov kev ua haujlwm ntawm sulfonamide rhiab heev.

Qhov zoo tshaj plaws pH thiab hydrophilic lub hauv paus ntawm lub qab zib pab txhawb rau lub cev ntawm lub qhov txhab, ua kom zoo sai, ua kom tsis nco qab.

Cov lus qhia rau siv (Txujci thiab ntau npaum li cas)

Cov tshuaj tsis yog npaj rau kev tswj hwm qhov ncauj, tsuas yog siv sab nraud nkaus xwb. Cov tshuaj nplaum tuaj yeem thov qhib qhov txhab, siv qhov tshwj xeeb ntawm kev hnav khaub ncaws pub. Cov tshuaj yog thov rau cov tawv nqaij ntxuav, pom cov cai ntawm asepsis, antisepticsCov. Qhov pom ntawm exudate, kev kho ua ntej ntawm daim tawv nqaij nrog kev daws yog pom zoo. boric acid 3%, lossis daws teeb meemchlorhexidine0,1%.

Cov lus qhia rau Argosulfan:cov tshuaj yog thov nrog ib txheej nyias ntawm 2-3 hli tuab txog thaum lub qhov txhab raug kaw tag nrho los yog kom txog rau thaum cov tawv nqaij hloov cev. Txhua hnub pom zoo rau 2-3 cov txheej txheem. Txhua hnub koj tuaj yeem thov tsis pub tshaj 25 g ntawm ointment. Lub sijhawm tiv thaiv ntawm kev kho mob yog 2 hli. Nrog lub sijhawm ntev, kev kho mob tas mus li, yuav tsum ua qhov kev soj ntsuam ntawm cov haujlwm ua haujlwm ntawm lub siab thiab lub raum.

Hauv cev xeeb tub (thiab lactation)

Nyob rau lub sijhawm ua poj niam tes taw cev xeeb tub Argosulfan tuaj yeem siv tsuas yog thaum mob nrawm, piv txwv, thaum muaj kev puas tsuaj rau daim tawv nqaij nrog thaj tsam ntawm ntau tshaj 20%. Kev pub mis niam Nws raug nquahu kom tshem tawm vim qee qhov nqus ntawm cov tshuaj.

Argosulfan Xyuas

Hauv kev xyaum kho mob, lub lee tau tsim nws tus kheej ua ib qho cuab yeej zoo hauv kev kho mob ntawm thaj tsam kub hnyiab. Cov chaw sib tham thiab cov chaw kho mob uas cov neeg mob ib txwm sib koom lawv qhov kev xav tsuas muaj kev tshuaj xyuas zoo txog Argosulfan. Cov niam tsev hluas tseem tawm lawv cov kev tshuaj xyuas txog cov tshuaj pleev, thiab qhia tias nws ua tau zoo los ntawm cov menyuam yaus, kev ua haujlwm siab hauv kev kho mob ntawm kev ua kom puas, txiav thiab mob.

Cov lus qhia rau kev siv Argosulfan: txoj kev thiab ntau npaum li cas

Argosulfan qab zib yog siv sab nraud, kev kho yog tsim los ntawm txoj kev qhib lossis siv cov ris tsho occlusive.

Cov tshuaj nplaum yog thov rau thaj tsam cuam tshuam thiab faib rau hauv ib txheej txawm ntawm 2-3 hli. Kev tswj cov mob yog nqa tawm hauv cov kab mob tsis huv 2-3 zaug hauv ib hnub kom txog thaum lub qhov txhab raug kho tag nrho lossis hloov nqaij tawv. Thaum kho, cov cream yuav tsum npog tag nrho cov chaw ntawm qhov txhab, yog tias ib feem ntawm qhov txhab qhib, txheej txheej yuav tsum tau rov qab.

Yog hais tias exudate cov ntaub ntawv thaum kho cov mob muaj qhov txhab nrog Argosulfan, ua ntej rov ua cov tshuaj nplaum, lub qhov txhab yuav tsum raug muab ntxuav ntawm nws thiab kho nrog ib qho kev siv tshuaj tua kab mob (kev daws teeb meem ntawm chlorhexidine 0.1%).

Qhov siab tshaj plaws tau tso cai noj qab haus huv txhua hnub ntawm qab zib yog 25 g. Lub sijhawm tiv thaiv ntev tshaj plaws tsis pub dhau ob lub hlis.