NovoMix - cov lus qhia rau kev siv, tshuaj xyuas, sib piv thiab tso tawm cov ntawv (tso tawm lossis daws rau subcutaneous txhaj ntawm 100 PIECES hauv 1 ml hauv rab koob tshuaj los yog cartridge) ntawm cov tshuaj rau kev kho mob ntshav qab zib rau cov laus, menyuam yaus thiab cev xeeb tub

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj yaj yeeb NovoMiksCov. Muab tswv yim los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg siv khoom ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws kho mob tshwj xeeb txog kev siv NovoMix hauv lawv cov kev coj ua. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Cov qauv ntawm NovoMix nrog cov qauv txheej txheem. Siv rau kev kho mob ntshav qab zib hauv cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation.

NovoMiks - Tus neeg sawv cev hypoglycemic. Nws yog ob-ncua kev ncua muaj xws li ntawm cov tshuaj insulin aspart (30% ua yeeb yam insulin analog) thiab muaju ntawm aspart tiv thaiv insulin (70% nruab nrab-ua yeeb yam insulin analog). Cov tshuaj muaj zog ntawm NovoMix yog cov tshuaj insulin aspart, tsim los ntawm cov qauv ntawm txoj kev tso ua ke deoxyribonucleic acid (DNA) biotechnology siv tshuaj Saccharomyces cerevisiae hom. Cov tshuaj insulin aspart yog equipotential soluble tib neeg insulin raws li nws cov molarity.

Kev poob qis hauv cov ntshav qab zib tshwm sim vim qhov nce ntxiv hauv nws txoj kev thauj mus los tom qab kev khi ntawm insulin aspart rau insulin receptors ntawm cov leeg nqaij thiab cov nqaij rog thiab ib txhij inhibition ntawm qabzib ntau los ntawm lub siab. Tom qab subcutaneous tswj hwm ntawm NovoMix, cov nyhuv tshwm sim tsis pub dhau 10-20 feeb. Qhov siab tshaj plaws pom tau pom nyob hauv thaj tsam li 1 txog 4 teev tom qab kev txhaj tshuaj. Lub sijhawm tiv thaiv ntawm cov tshuaj nce mus txog 24 teev.

Muaj pes tsawg leeg

Ob-theem insulin aspart + excipients (30 Penfill, 30 Flexpen, 50 Flexpen, 70 Flexpen).

Cov Tshuaj Pharmacokinetics

Hauv cov tshuaj insulin aspart, kev hloov pauv ntawm cov amino acid proline ntawm txoj hauj lwm B28 rau aspartic acid txo qhov nyiam ntawm molecules los ua hexamers hauv cov tshuaj NovoMix feem, uas tau pom nyob hauv tib neeg cov kua dej. Hauv qhov no, insulin aspart (30%) yog nqus tau los ntawm cov rog subcutaneous sai dua li cov tshuaj solulin hauv cov neeg insulin biphasic. Qhov seem 70% poob rau lub ntsej muag crystalline ntawm cov tshuaj tiv thaiv-insulin aspart, qhov kev nqus ntawm uas yog tib yam li ntawm tib neeg nruab nrab tiv thaiv Hagedorn (NPH insulin). Hauv cov neeg ua haujlwm noj qab haus huv, tom qab tswj hwm kev noj qab haus huv ntawm NovoMix tshuaj ntawm tus nqi 0.2 PIECES rau 1 kg ntawm lub cev qhov hnyav, qhov siab tshaj plaws ntawm cov tshuaj insulin aspart hauv cov ntshav cov ntshav tau mus txog tom qab 60 feeb. Ib nrab-lub neej ntawm NovoMix, uas qhia txog tus nqi ntawm kev nqus ntawm cov tshuaj tiv thaiv-cuam tshuam nrog ntu, yog 8-9 teev. Ntshav dej insulin qib rov qab rau hauv lub hauv paus 15-18 teev tom qab kev saib xyuas ntawm cov tshuaj ntawm cov tshuaj. Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, qhov siab tshaj plaws tau mus txog 95 feeb tom qab kev tswj hwm thiab nyob twj ywm saum toj saud tsawg kawg 14 teev

Cov Khoom Qhia

cov ntshav qab zib tsis yog insulin-tiv thaiv kev mob ntshav qab zib,
insulin-tiv thaiv ntshav qab zib mellitus.

Tso Tawm Cov Ntawv

Kev Rau Txim rau lub luag haujlwm tswj ntawm 100 tus PIECES hauv 1 ml hauv rab koob tshuaj los yog 3 ml cartridge (qee zaus yuam kev hu ua txoj kev daws teeb meem).

Cov lus qhia rau kev siv thiab ntau npaum li cas

Cov tshuaj yog muab tshuaj subcutaneously. Koj tsis tuaj yeem nkag rau NovoMiks txhaj tshuaj, vim tias qhov no tuaj yeem ua rau mob ntshav qab zib siab heev. Intramuscular thawj coj ntawm NovoMix tseem yuav tsum zam. NovoMix tsis tuaj yeem siv rau subcutaneous insulin infusions hauv cov twj tso kua mis.

Cov koob tshuaj NovoMix yog txiav txim los ntawm tus kws kho mob tshwj xeeb hauv txhua kis, raws li qhov xav tau ntawm tus neeg mob. Txhawm rau kom ua tiav qib siab ntawm glycemia, nws raug nquahu kom tswj cov concentration ntawm cov piam thaj hauv cov ntshav thiab kho qhov ntau ntawm cov tshuaj.

NovoMix tuaj yeem raug kho rau cov neeg mob ntshav qab zib hom 2 ntshav qab zib mellitus xws li kev kho mob monotherapy lossis sib xyaw nrog cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj, nyob rau hauv cov teeb meem uas cov ntshav qabzib hauv lub cev tsis txaus los ntawm kev siv tshuaj los ntawm lub qhov ncauj hypoglycemic xwb.

Rau cov neeg mob uas muaj ntshav qab zib hom 2 uas tau tsim cov tshuaj insulin thawj zaug, qhov xav kom pib ntawm NovoMix yog 6 chav ua ntej noj tshais thiab 6 chav ua ntej noj hmo. Nws tseem raug tso cai los qhia 12 chav nyob rau ib hnub nyob rau yav tsaus ntuj (ua ntej noj hmo).

Hloov chaw ntawm tus neeg mob los ntawm lwm yam tshuaj insulin

Thaum hloov mus rau tus neeg mob los ntawm biphasic human insulin mus rau NovoMix, ib qho yuav tsum pib nrog tib lub koob tshuaj thiab hom kev tswj hwm. Tom qab ntawv kho cov koob tshuaj raws li qhov xav tau ntawm tus neeg mob. Raws li ib txwm muaj, thaum hloov tus neeg mob mus rau ib hom tshuaj insulin tshiab, kev tswj hwm kev tswj hwm nruj yog qhov tsim nyog thaum lub sijhawm hloov ntawm tus neeg mob thiab hauv thawj lub lis piam ntawm kev siv tshuaj tshiab.

Nws yog qhov ua tau kom ntxiv dag zog rau NovoMix kev kho mob los ntawm kev hloov pauv ntawm ib zaug tshuaj mus rau ib ob. Nws raug nquahu tias tom qab tau txais 30 koob ntawm cov tshuaj hloov mus rau kev siv NovoMix 2 zaug hauv ib hnub, faib qhov koob rau hauv ob qhov sib luag - thaum sawv ntxov thiab yav tsaus ntuj (ua ntej noj tshais thiab noj hmo).

Txoj kev hloov mus rau kev siv NovoMix 3 zaug hauv ib hnub yog tau los ntawm kev faib cov koob tshuaj thaum sawv ntxov ua ob ntu sib luag thiab qhia ob ntu no thaum sawv ntxov thiab thaum noj su (peb zaug noj ib hnub).

Yuav kom kho qhov koob tshuaj NovoMix, qhov qis tshaj ntawm cov ntshav nrawm nyob hauv peb hnub dhau los yog siv. Txheeb xyuas qhov tsim nyog ntawm cov koob tshuaj dhau los, siv tus nqi ntawm cov concentration ntawm cov piam thaj hauv cov ntshav ua ntej noj mov tom ntej.

Kev hloov pauv koob tshuaj tuaj yeem nqa tawm ib zaug ib lub lim tiam kom txog thaum lub hom phiaj nqi ntawm glycated hemoglobin (HbA1c) tau mus txog. Tsis txhob nce qhov koob tshuaj ntawm cov tshuaj yog tias lub ntsej muag hypoglycemia tau pom nyob hauv lub sijhawm no. Kev hloov koob tshuaj yuav tsim nyog thaum ua kom tus neeg mob lub cev ua si, hloov nws li kev noj zaub mov kom zoo, lossis muaj lub ntsej muag comorbid.

Yog tias qhov concentration ntawm cov piam thaj hauv cov ntshav ua ntej noj mov tsawg dua 4.4 mmol / l (tsawg dua 80 mg / dl), qhov tshuaj ntawm NovoMix yuav tsum raug txo los ntawm 2 pawg. Thaum cov concentration ntawm cov piam thaj hauv cov ntshav ua ntej noj mov 4.4-6.1 mmol / l (80-110 mg / dl), tsis tas yuav hloov kho cov tshuaj. Yog tias cov concentration ntawm cov piam thaj hauv cov ntshav ua ntej noj mov yog 6.2-7.8 mmol / l (111-140 mg / dl), qhov koob tshuaj yuav tsum tau nce ntxiv los ntawm 2 pawg. Nyob rau theem ntawm cov piam thaj ntawm 7.9-10 mmol / l (141-180 mg / dl) - nce ntxiv los ntawm 4 pawg. Yog tias qhov kev nyeem ntawm cov piam thaj hauv cov ntshav ua ntej noj mov ntau dua 10 mmol / l (ntau dua 180 mg / dl) - nce ntawm 6 ib pawg.

Thaum siv cov tshuaj insulin, nyob rau hauv cov neeg mob ntawm cov pab pawg tshwj xeeb nws yuav tsum ua tib zoo saib xyuas cov kua nplaum hauv cov ntshav thiab kho cov tshuaj insulin raws li tus kheej.

NovoMix yuav tsum tau tswj hwm subcutaneously hauv tus ncej puab lossis sab hauv plab phab ntsa. Yog tias qhov xav tau, cov tshuaj no tuaj yeem siv rau hauv xub pwg lossis pob tw. Nws yog ib qho tsim nyog yuav tau hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical kom tiv thaiv kev txhim kho ntawm lipodystrophy.

Ib yam li lwm cov tshuaj insulin, lub sijhawm ntawm NovoMix nyob ntawm lub koob tshuaj, thaj chaw txhaj tshuaj, ntshav khiav ceev, qhov kub thiab qib ntawm lub cev qoj ib ce.

Piv nrog biphasic tib neeg cov tshuaj insulin, NovoMix pib ua kom nrawm dua, yog li nws yuav tsum raug tswj hwm tam sim ntawd ua ntej muaj kev txom nyem. Yog tias tsim nyog, koj tuaj yeem nkag mus rau NovoMiks tsis ntev tom qab noj tus neeg thov khawv.

Cov lus qhia rau tus neeg mob

NovoMix thiab koob yog npaj rau cov tib neeg siv nkaus xwb. Tsis txhob ntim roj los yog cwj mem. Txhua zaus yuav tsum siv rab koob tshiab rau txhua txoj kev txhaj tshuaj tiv thaiv kev kis mob. Nws yuav tsum qhia txog tus neeg mob uas xav kom sib xyaw NovoMix kev ncua tsis pub dhau ua ntej siv.

Ua ntej siv NovoMix, kos daim ntawv lo kom paub tseeb tias hom tshuaj insulin raug xaiv. Txhua zaus yuav tsum kuaj xyuas cov cartridge, suav nrog rubber piston. Tsis txhob siv lub cartridge yog tias nws pom kev puas tsuaj lossis qhov sib txawv pom ntawm lub piston thiab daim tawv dawb ntawm daim cartridge. Rau cov kev taw qhia ntxiv, saib mus rau cov lus qhia kom siv cov txheej txheem rau txheej txheem insulin.

Koj tsis tuaj yeem siv NovoMix hauv cov xwm txheej hauv qab no:

yog tias tus neeg mob tau ua xua (qhov tsis haum lub cev) rau insulin aspart lossis ib feem twg ntawm NovoMix,
yog tias tus neeg mob xav tias yuav ua lub ntsej muag ntshav qab zib qis (cov ntshav qab zib qis),
rau subcutaneous insulin infusion hauv insulin twj,
yog tias lub cartridge los yog cov khoom siv ntxig nrog daim cartridge uas tau nruab yog poob qis los yog lub cartridge raug puas los yog tsoo,
yog tias qhov chaw cia khoom ntawm cov tshuaj tau txhaum cai lossis nws khov,
yog tias cov tshuaj insulin tsis hloov zuj zus dawb thiab yog huab tom qab sib tov,
yog hais tias nyob rau hauv qhov kev npaj tom qab sib xyaw nws muaj cov lumps dawb lossis cov khoom dawb uas lo rau hauv qab lossis phab ntsa ntawm daim cartridge.

Sab sij huam

urticaria, tawv nqaij ua pob,
tshuaj tiv thaiv anaphylactic,
qog ntshav,
peripheral neuropathy (mob mob neuropathy),
kev ua haujlwm tsis meej
cov ntshav qab zib retinopathy,
ua yeeb yaj kiab
o tuaj
kev tawm ntawm qhov chaw txhaj tshuaj.

Kev mob ntshav qab zib yog qhov tshwm sim feem ntau tshwm sim. Nws tuaj yeem tsim kho yog tias qhov koob tshuaj insulin ntau dhau lawm hauv kev sib txuas nrog qhov xav tau ntawm cov tshuaj insulin. Kev mob ntshav nce siab ntau dhau los tuaj yeem ua rau tsis nco qab thiab / lossis rov huam, ib ntus lossis tsis tuaj yeem ua haujlwm ntawm lub hlwb kom mus txog rau qhov ua rau muaj kev ploj tuag. Cov tsos mob ntawm tus mob hypoglycemia, raws li txoj cai, tshwm sim sai. Cov no suav nrog kev tawm hws txias, pallor ntawm daim tawv nqaij, ua rau qaug zog, tshee lossis tshee tshee, ntxhov siab, nkees txawv lossis qaug zog, tsis meej pem, qis zuj zus, nkees nkees, tshaib plab, tsis pom kev, mob taub hau, xeev siab thiab lub plawv dhia. Cov kev tshawb fawb soj ntsuam pom tau tias qhov tshwm sim ntawm kev mob ntshav qab zib tsawg txawv nyob ntawm cov neeg mob, noj tshuaj ntau ntxiv, thiab tswj glycemic. Hauv kev sim tshuaj, tsis muaj qhov sib txawv ntawm qhov tshwm sim tag nrho ntawm kev mob hypoglycemia hauv cov neeg mob tau txais kev kho mob aspart insulin thiab cov neeg mob siv tib neeg cov tshuaj insulin.

Cov Yuav Tsum Muaj

ntxiv cov tib neeg rhiab rau insulin aspart lossis ib qho ntawm cov tshuaj,
cov me nyuam qis dua 6 xyoo.

Cev xeeb tub thiab lactation

Cov kev paub txog mob thaum siv NovoMix thaum cev xeeb tub muaj tsawg. Cov kev tshawb fawb txog nws qhov kev siv hauv cov poj niam cev xeeb tub tsis tau ua.

Nyob rau lub sijhawm ntawm kev pib ua kom cev xeeb tub thiab nyob rau tag nrho nws lub sijhawm, nws yuav tsum tau ua tib zoo saib xyuas cov neeg mob uas muaj ntshav qab zib mellitus thiab saib xyuas qhov kev nyeem ntawm cov piam thaj hauv cov ntshav. Qhov xav tau tshuaj insulin, raws li txoj cai, txo qis hauv thawj lub hlis thiab maj mam nce hauv qib thib 2 thiab 3 ntawm cev xeeb tub. Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub.

Thaum lub sijhawm pub mis niam, NovoMix tuaj yeem siv tsis muaj kev txwv. Qhov kev coj ntawm cov tshuaj insulin rau leej niam noj mis tsis yog kev hem thawj rau tus menyuam. Txawm li cas los xij, nws yuav tsim nyog kho qhov tshuaj ntawm cov tshuaj.

Siv rau menyuam yaus

Nws tsis pom zoo rau cov menyuam yaus hnub nyoog qis dua 6 xyoo, txij li kev tshawb fawb txog kev siv NovoMix 30 Penfill lossis FlexPen tsis tau ua.

NovoMix tuaj yeem siv los kho cov menyuam yaus thiab cov tub ntxhais hluas uas muaj hnub nyoog tshaj 10 xyoo nyob rau hauv rooj plaub uas xav siv cov tshuaj insulin ua ntej dua. Cov ntaub ntawv khomob tsawg tsawg muaj rau cov menyuam yaus 6–9 xyoo.

Siv rau cov neeg mob laus

NovoMix tuaj yeem siv rau cov neeg mob laus, txawm li cas los xij, kev paub nrog nws siv nrog kev siv tshuaj ntawm qhov ncauj hypoglycemic hauv cov neeg mob laus dua 75 xyoo tau txwv.

Cov lus qhia tshwj xeeb

Ua ntej taug kev ntev ntev uas muaj feem xyuam nrog kev hloov chaw ntawm lub sijhawm, tus neeg mob yuav tsum sab laj nrog lawv tus kws kho mob, vim tias hloov chaw ntawm lub sijhawm txhais tau tias tus neeg mob yuav tsum noj thiab noj cov tshuaj insulin rau lwm lub sijhawm.

Qhov tsis txaus noj tshuaj lossis tsis ncua kev kho mob, tshwj xeeb tshaj yog nrog hom 1 mob ntshav qab zib mellitus, tuaj yeem ua rau kev loj hlob ntawm hyperglycemia lossis ntshav qab zib ketoacidosis. Raws li txoj cai, thawj cov tsos mob ntawm hyperglycemia tshwm maj maj ntau ntau teev lossis hnub. Cov tsos mob ntawm hyperglycemia yog nqhis dej, tso zis ntau ntxiv, xeev ntuav, ntuav, nkees, liab thiab tawv nqaij ntawm daim tawv nqaij, lub qhov ncauj qhuav, tsis qab los noj mov, thiab tsis hnov tsw ntawm Acetone hauv cov pa ua pa. Yog tias tsis muaj kev kho mob uas tsim nyog, hyperglycemia hauv cov neeg mob uas muaj ntshav qab zib hom 1 tuaj yeem ua rau ketoacidosis mob ntshav qab zib, uas yog ib qho mob uas yuav ua rau tuag taus.

Noj zaub mov los sis ua tej yam qoj ib ce tsis txaus yuav ua rau lub qog ntshav qab zib. Kev mob ntshav qog ntshav siab kuj tseem tuaj yeem txhim kho tau yog tias koob tshuaj insulin ntau dhau heev lawm hauv kev sib piv rau tus neeg mob cov kev xav tau. Piv nrog biphasic tib neeg cov tshuaj insulin, NovoMix muaj cov txiaj ntsig hypoglycemic ntau dua li ntawm 6 teev tom qab kev tswj hwm. Hauv qhov no, qee qhov xwm txheej, nws yuav tsim nyog yuav tau kho lub koob tshuaj insulin thiab / los yog hom xwm ntawm kev noj haus.

Tom qab them nyiaj rau cov pluas noj carbohydrate, piv txwv li, thaum lub zog kev kho mob insulin, cov neeg mob yuav muaj cov tsos mob tshwm sim ua ntej ntawm hypoglycemia, uas cov neeg mob yuav tsum tau ceeb toom. Cov paib ceeb toom ib txwm yuav ploj thaum muaj ntshav qab zib ntev. Txij li NovoMix yuav tsum siv nyob rau hauv kev sib txuas ncaj qha nrog kev noj zaub mov, ib qho yuav tsum coj mus rau hauv lub siab ceev ntawm qhov pib ntawm cov nyhuv ntawm cov tshuaj hauv kev kho mob ntawm cov neeg mob concomitant los yog noj cov tshuaj uas ua rau qeeb dua qhov nqus ntawm cov khoom noj.

Cov kab mob tsis haum, tshwj xeeb tshaj yog kis thiab nrog kub taub hau, feem ntau ua rau lub cev xav tau cov tshuaj insulin. Koob tshuaj kuj tseem yuav tsum tau ua yog tias tus neeg mob tau muaj cov kab mob ntawm lub raum, mob siab, ua haujlwm tsis zoo hauv lub qog, lub caj pas pituitary lossis lub qog ua haujlwm.

Thaum hloov mus rau tus neeg mob mus rau lwm hom insulin, cov tsos mob thaum ntxov ntawm kev paub ua ntej ntawm hypoglycemia tuaj yeem hloov lossis tsis tau tshaj tawm dua li cov uas tau pom nrog hom insulin yav dhau los.

Hloov chaw ntawm tus neeg mob los ntawm lwm yam tshuaj insulin

Hloov chaw ntawm tus neeg mob mus rau ib hom tshiab ntawm insulin lossis kev tsim tshuaj insulin ntawm lwm cov tuam txhab yuav tsum tau ua nyob ntawm kev saib xyuas mob nkeeg nruj. Yog tias koj hloov qhov kev xav, hom, chaw tsim khoom thiab hom (tib neeg insulin, kev tsim ntawm tib neeg cov tshuaj insulin) ntawm cov tshuaj insulin thiab / lossis cov qauv ntawm kev tsim khoom, yuav tsum tau hloov cov koob tshuaj. Cov neeg mob hloov ntawm lwm cov tshuaj insulin los kho nrog NovoMix tej zaum yuav tsum tau txhaj tshuaj ntau dua lossis hloov cov koob tshuaj piv rau cov koob tshuaj ntawm kev siv tshuaj insulin uas tau siv yav dhau los. Yog tias tsim nyog, kev hloov kho tshuaj, nws tuaj yeem ua twb tau dhau los ntawm thawj kev txhaj tshuaj lossis thaum thawj lub limtiam lossis hli ntawm kev kho.

Cov tshuaj tiv thaiv ntawm qhov chaw txhaj tshuaj

Ib yam li lwm cov tshuaj insulin, cov tshuaj tiv thaiv tuaj yeem tsim kho ntawm qhov chaw txhaj tshuaj, uas pom los ntawm qhov mob, liab liab, tso zis, mob, mob ntshav, txhaws thiab khaus. Kev hloov pauv ntawm qhov chaw txhaj tshuaj hauv tib thaj av ib puag ncig ntawm lub cev txo qhov kev pheej hmoo ntawm cov kev cuam tshuam no. Cov kev tawm tsam feem ntau yuav ploj mus li ntawm ob peb hnub mus rau ntau lub lis piam. Tsis tshua muaj qee zaum, NovoMix tuaj yeem yuav tsum txiav tawm vim tias muaj kev cuam tshuam ntawm qhov chaw txhaj tshuaj.

Cov tshuaj tua kab mob insulin

Thaum siv cov tshuaj insulin, kev tsim cov tshuaj tiv thaiv yog ua tau. Tsis tshua muaj teeb meem, kev tsim cov tshuaj tiv thaiv lub cev yuav xav tau cov tshuaj insulin kom tiv thaiv cov mob ntawm hyperglycemia lossis hypoglycemia.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Lub peev xwm ntawm cov neeg mob kom pom tseeb thiab tus nqi tshuaj tiv thaiv tej zaum yuav ua rau lub sijhawm tsis muaj ntshav qab zib, uas tuaj yeem tsim kev puas tsuaj rau cov xwm txheej uas cov peev xwm no tshwj xeeb tshaj yog (piv txwv li, thaum tsav tsheb lossis ua haujlwm nrog tshuab). Cov neeg mob yuav tsum tau qhia rau kev ntsuas kom tiv thaiv kev mob ntshav qab zib thaum tsav tsheb lossis ua haujlwm nrog cov tshuab. Qhov no yog qhov tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj los yog ploj zuj zus ntawm cov tshwm sim ntawm kev muaj ntshav qab zib lossis kev txom nyem los ntawm kev pheej muaj ntshav tsis txaus. Hauv cov xwm txheej no, kev tsim nyog ntawm kev tsav tsheb thiab ua cov haujlwm no yuav tsum raug txiav txim siab.

Yeeb tshuaj sib cuam tshuam

Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin. Cov nyhuv hypoglycemic ntawm insulin yog txhim kho los ntawm qhov ncauj hypoglycemic tshuaj, monoamine oxidase inhibitors (MAOs), angiotensin converting enzyme inhibitors (ACEs), carbonic anhydrase inhibitors, tsis-xaiv beta-adrenergic thaiv cov kab mob, bromocriptolides, tetrabolofenolenenenenenenenofenolenen fenfluramine, lithium npaj, salicylates.

Cov nyhuv hauv lub ntsej muag ntawm insulin tsis muaj zog los ntawm kev tiv thaiv hauv lub qhov ncauj, glucocorticosteroids (GCS), cov thyroid hormones, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, somatropin, danazole, clonidine, calcium channel blockers, diazotinotin, morphine.

Beta-blockers tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib.

Octreotide / lanreotide tuaj yeem nce ntxiv thiab txo qis qhov xav tau ntawm lub cev.

Cawv yuav ua kom cov ntshav qis los tsis txaus.

Cov kab mob ntawm kev loj hlob ntawm kev mob plawv ntev (CHF) tau tshaj tawm qhia txog kev kho mob rau cov neeg mob thiazolidinediones sib xyaw nrog kev npaj tshuaj insulin, tshwj xeeb tshaj yog tias cov neeg mob no muaj kev phom sij los txhim kho CHF. Qhov tseeb no yuav tsum raug coj los txiav txim siab thaum sau ntawv kho kev sib xyaw nrog thiazolidinediones thiab tshuaj insulin rau cov neeg mob. Thaum sau tshuaj rau kev kho ua ke, nws yog ib qho tsim nyog los soj ntsuam kev kho mob ntawm cov neeg mob kom paub cov cim thiab cov tsos mob ntawm lub plawv tsis ua hauj lwm, nce lub cev hnyav thiab muaj cov edema. Yog hais tias cov tsos mob ntawm lub plawv tsis zoo nyob rau hauv cov neeg mob, kev kho mob nrog thiazolidinediones yuav tsum tau tsum txiav.

Txij li cov kev tshawb fawb ua tsis tau coj los ua, NovoMix yuav tsum tsis txhob sib xyaw nrog lwm cov tshuaj.

Cov tshuaj Analogues ntawm cov tshuaj NovoMiks

Cov qauv ntawm cov qauv ua haujlwm:

NovoMix 30 Penfill,
NovoMix 30 FlexPen,
NovoMix 50 FlexPen,
NovoMix 70 FlexPen.

Cov tshuaj tiv thaiv tshuaj NovoMix los ntawm pab pawg pharmacological (insulins):

Actrapid
Apidra
Berlinsulin,
Biosulin
Brinsulmidi
Brinsulrapi
Cia quaj
Gensulin
Qwj-insulin C
Isofan-Insulin Ntiaj Teb Khob,
Iletin
Insulin aspart,
Tshuaj insulin glargine,
Insulin glulisin,
Cov tshuaj insulin,
Tshuaj Insulin Isofanicum,
Cov ntaub thaiv insulin,
Tshuaj insulin maxirapid,
Insulin soluble nruab nrab
Insulin c
Nqaij npuas ua kua txig ntau dhau los ua tiav MK,
Insulin semilent,
Cov tshuaj Insulin Ultralente,
Neeg insulin
Tshuaj insulin QMS,
Insulong
Khoom Ntsuas
Neeg tsis ntseeg xav
Soj ntsuam
Mob siab
Siv tshuaj tua kabmob C
Lauj Teeb
Levemir,
Mikstard
Monoinsulin
Monotard
NovoMix 30 Penfill,
NovoMix 30 FlexPen,
NovoMix 50 FlexPen,
NovoMix 70 FlexPen,
NovoRapid,
Pensulin,
Cov tshuaj tiv thaiv insulin
Protafan
Recombinant tib neeg cov insulin,
Rinsulin
Rosinsulin,
Tresiba,
Tujeo SoloStar,
Ultratard NM,
Homolong
Qhov Homorap
Neej Neeg,
Neej Neeg Dab
Neeg lim hiam.

Endocrinologist cov tswv yim

Txhua tus ntawm kuv cov neeg mob ntshav qab zib muaj cov ntsej muag hauv tsev. Kuv sim qhia txhua tus neeg mob siv NovoMix kom raug, yuav kho cov koob tshuaj li cas. Tab sis, hmoov tsis, tsis yog txhua tus mob ntshav qab zib yog lub luag hauj lwm rau kev kho mob. Yog li no, muaj qee lub sijhawm thaum lawv txhim kho lub xeev ntawm hypo- lossis hyperglycemia ntawm qhov sib txawv zuj zus. Qee tus neeg mob tseem yuav tsum tau mus pw tsev kho mob. Tab sis feem ntau, NovoMix tau pom zoo zoo. Lwm qhov tsis zoo rau nws tshwm sim muaj tsawg. Tsuas yog nyob ntawm no lipodystrophy hauv thaj chaw ntawm kev tswj hwm tshuaj rau cov neeg mob ntshav qab zib nrog kev paub yuav zam tsis dhau.

Kev piav qhia ntawm daim ntawv tshuaj

Homogeneous dawb lump-tsis pub muab ncua. Flakes tuaj yeem tshwm sim hauv tus qauv.

Thaum sawv ntsug, qhov kev ncua tawm delaminates, sib sau ua ib qho dawb nag lossis daus uas tsis muaj xim lossis yuav luag tsis muaj xim.

Thaum tov cov nag lossis daus raws li cov qauv qhia hauv cov lus qhia rau kev siv kho mob, ib qho kev ncua homogeneous yuav tsum tau tsim.

Tus tsim tawm thiab tsim khoom siv ntawm cov cuab yeej no yog lub tuam txhab Danish Novonordisk. Lub ntsiab tseem ceeb ntawm Novomix yog kev pib nrawm ntawm kev pib, kom cov tshuaj tuaj yeem nkag mus rau hauv lub cev txawm tias muaj zaub mov lossis tam sim ntawd tom qab noj mov. Qhov no ua rau cov tshuaj yooj yim heev rau kev kho mob ntawm cov menyuam yaus thiab cov hluas, thiab rau cov neeg laus uas tsis ua raws li cov kev cai niaj hnub.

Muaj peev xwm tswj cov tshuab

Yog tias, vim li cas rau ntau yam, hypoglycemia tshwm sim thaum noj cov tshuaj, tus neeg mob yuav tsis muaj peev xwm mloog tau zoo thiab muaj peev xwm teb tau qhov tshwm sim rau nws. Yog li ntawv, tsav tsheb los yog lub tshuab yuav tsum raug txwv. Txhua tus neeg mob yuav tsum paub txog kev ntsuas tsim nyog los tiv thaiv cov ntshav qab zib cov ntshav kom qis, tshwj xeeb yog tias koj yuav tsum tau tsav tsheb.

Hauv cov xwm txheej uas FlexPen lossis nws qhov tseeb ntawm lub ntsej muag siv, nws yuav tsum ua tib zoo ntsuas kev nyab xeeb thiab kev pom zoo ntawm kev tsav tsheb, tshwj xeeb tshaj yog nyob rau qee qhov xwm txheej ntawm cov ntshav qog ntshav tsis muaj zog lossis tsis tuaj.

Nosological kev faib tawm (ICD-10)

Txheeb xyuas cov tshuaj muaj txiaj ntsig tseem ceeb nyob ntawm lawv cov sijhawm thiab kev ua haujlwm. Nws yog tsim nyog sau cia tias muaj ntau hom tshuaj sib xyaw ua ke uas tuaj yeem hloov qee yam tshuaj los ntawm kev xaiv txoj kev siv tshuaj. Cov piam thaj txo cov tshuaj tau muab faib rau cov hom hauv qab no:

kev txiav txim luv
nruab nrab sijhawm
kev kub ceev
Lub sijhawm ua haujlwm ntev
sib xyaw (sib xyaw) txhais tau tias.

Siv thaum cev xeeb tub

Cov kev paub txog mob thaum siv NovoMix® 30 Penfill® / FlexPen® thaum cev xeeb tub muaj tsawg.

Cov kev tshawb fawb txog kev siv NovoMix® 30 Penfill® / FlexPen® hauv cov poj niam cev xeeb tub tsis tau ua.

Thaum cev xeeb tub thiab lactation, kev kho mob hauv kev paub nrog cov tshuaj muaj tsawg. Hauv chav kawm txog kev sim ntawm cov tsiaj, nws tau pom tias aspart li tib neeg cov tshuaj insulin tsis muaj peev xwm ua rau muaj kev tsis zoo rau lub cev (teratogenic lossis embryotoxic).

Cov kev soj ntsuam nrog NovoMix® 30 FlexPen® thaum cev xeeb tub muaj tsawg.

Nyob rau lub sijhawm ntawm qhov pib ua tau thiab thaum tag nrho lub sijhawm cev xeeb tub, ua tib zoo saib xyuas cov xwm txheej ntawm cov neeg mob ntshav qab zib mellitus thiab saib xyuas qib ntawm cov piam thaj hauv cov ntshav ntshav yog qhov tsim nyog. Qhov xav tau rau insulin, raws li txoj cai, txo qis hauv thawj peb hlis thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb ntawm cev xeeb tub.

Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub.

Lus Tshaj Tawm

xyov. d / nyob rau hauv. 100 IU / ml cartridge 3 ml, zes. rau hauv daim ntawv xaum hluav taws xob, No. 1 65.2 UAH.

xyov. d / nyob rau hauv. 100 IU / ml cartridge 3 ml, zes. rau hauv daim ntawv xaum hluav taws xob, No. 5 332.07 UAH.

Cov tshuaj insulin aspart 100 U / ml

ib tug xov tooj ntawm cov tshuaj cuam tshuam rau cov metabolism hauv cov piam thaj, uas yuav tsum tau txiav txim siab thaum txiav txim qhov koob tshuaj ntawm insulin.

Cov tshuaj uas txo qis qhov xav tau ntawm cov tshuaj insulin: cov tshuaj tiv thaiv kab mob hypoglycemic, octreotide, MAO inhibitors, tsis xaiv-β-adrenergic receptor blockers, ACE inhibitors, salicylates, cawv, anabolic steroids thiab sulfonamides.

Cov tshuaj uas ua kom muaj kev xav tau ntxiv rau cov tshuaj insulin: tshuaj tiv thaiv qhov ncauj, thiazides, glucocorticosteroids, cov thyroid hormones, sympathomimetics thiab danazol. Block-adrenoreceptor blockers tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib, haus dej cawv - kom txhim kho thiab ua kom ntev ntawm qhov kev tiv thaiv hypoglycemic ntawm insulin.

Incompatibility. Qhov sib ntxiv ntawm qee yam tshuaj rau cov tshuaj insulin tuaj yeem ua rau nws rhuav tshem, piv txwv li, cov tshuaj uas muaj thiols lossis sulfites. NovoMix 30 Flexpen tsis tuaj yeem raug ntxiv rau txoj kev daws teeb meem.

Ib daim ntawv teev tag nrho cov tshuaj muaj txiaj ntsig tau txhim kho uas tuaj yeem cuam tshuam cov metabolism hauv cov piam thaj hauv tib neeg lub cev. Qhov no raug nquahu kom coj mus rau hauv qhov nyiaj thaum xam xyuas qhov yuav tsum tau tshuaj. Nws raug nquahu kom teev ntawm qhov kev txhais tau uas txo qis qhov xav tau ntawm tib neeg lub cev rau cov tshuaj insulin:

qhov ncauj hypoglycemic,
MAO inhibitors
octreotide
ACE inhibitors
salicylates.

Tseem muaj cov neeg sawv cev uas ua rau kev xav tau ntxiv siv Novomix Flekspen insulin lossis nws qhov kev hloov pauv ntawm Novomix Penfill. Peb tab tom tham txog kev tiv thaiv qhov ncauj, Danazole thiab dej cawv.

Ntxiv rau, peb yuav tsum tsis txhob hnov qab txog thiazides, HSCs (qia hlwb), nrog rau kev siv cov thyroid hormones. Muab tag nrho cov no, Kuv xav kos lub ntsej muag rau hauv dab tsi yog cov yam ntxwv tseem ceeb hauv daim ntawv thov, nrog rau qhov ntau npaum li cas ntawm cov tshuaj tiv thaiv uas hais tawm.

Cov tshuaj yeeb dej caw uas sib luag nrog tib neeg cov kua dej tau txhim kho. Lawv tuaj yeem pib lawv qhov kev nqis tes tsuas yog 5 feeb tom qab txhaj rau cov ntshav.

Kev hloov pauv ntawm cov tsis tuaj yeem ua tiav tuaj yeem nqa tusyees thiab tsis ua rau pom kev zoo li ntawm hypoglycemia. Kev npaj tshuaj insulin yog tsim tshwj xeeb vim yog tsob ntoo keeb kwm.

Txhais tau tias muaj qhov txawv txav los ntawm lawv cov kev hloov pauv ntawm acidic mus rau cov khoom qub, cov ua kom tiav.

Insulin analogs tau txais los ntawm kev siv thev naus laus zis, suav nrog DNA tso tawm tshiab. Rov ua dua tsim cov zoo zoo analogues ntawm luv luv insulin thiab lwm yam kev ua, uas tau ua raws li cov khoom lag luam tseeb.

Cov tshuaj tso cai rau koj kom tau txais txiaj ntsig zoo ntawm kev pheej hmoo ntawm qab zib poob thiab cov txiaj ntsig glycemia. Kev tsis muaj cov tshuaj hormone ntau lawm tuaj yeem ua rau tus neeg mob mus rau hauv lub xeev coma qab.

Ib qho yeeb yaj kiab rau kev tswj hwm hauv cov roj ntsha subcutaneous, tsim los txhim kho cov piam thaj hauv siab, thiab nrog cov khoom zoo ib yam li tib neeg cov insulin. Cov tshuaj yog tsim los tswj cov tshuaj hypoglycemic.

Nrog rau txoj haujlwm tseem ceeb, cov tshuaj nqa tawm ua ke pom tawm ntawm cov piam thaj hauv lub siab. Qhov kev txiav txim pib yuav luag tam sim ntawd tom qab cov tshuaj pom.

Cov tshuaj yuav tsum tau siv los ntawm cov neeg muaj kev txom nyem los ntawm hom 1 thiab hom 2 mob ntshav qab zib mellitus, nrog rau kom txo qis tshaj qhov hnyav, los tiv thaiv hyperglycemic coma. Koj yuav tsum hloov mus rau lwm cov tshuaj yog tias koj fab rau ntawm ib qho tshuaj ntxiv lossis yog tias muaj ntshav qab zib tsawg.

Muaj ntau cov tshuaj uas tuaj yeem cuam tshuam cov metabolism hauv cov piam thaj hauv lub cev, uas yuav tsum tau coj mus rau hauv kev suav thaum xam qhov yuav tsum tau noj.

Txhais tau tias kev txo qis qhov xav tau rau insulin hormone suav nrog:

qhov ncauj hypoglycemic,
MAO inhibitors
octreotide
ACE inhibitors
salicylates,
anabolics
sulfonamides,
cawv muaj
tsis xaiv cov khoom blockers.

Nws kuj muaj cov cuab yeej uas ua rau kom qhov kev xav tau ntxiv rau kev siv NovoMix 30 FlexPen insulin lossis nws cov roj ntsha sib txawv:

tshuaj tiv thaiv qhov ncauj
danazol
cawv
thiazides,
GSK,
cov thyroid hormones.

Hypoglycemic kev txiav txim ntawm cov tshuaj txhim khu qhov ncauj hypoglycemic tshuaj, Mao inhibitors, ACE inhibitors, carbonic anhydrase inhibitors, xim beta-blockers, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium npaj etanolsoderzhaschie npaj Cov.

Cov lus qhia rau tus neeg mob

kev noj tshuaj ntawm cov tshuaj insulin ib leeg zuj zus thiab txiav txim los ntawm tus kws kho mob raws li qhov xav tau ntawm tus neeg mob. Txij li thaum cov nyhuv ntawm NovoMix 30 FlexPen sai dua biphasic tib neeg cov tshuaj insulin, nws yuav tsum raug tswj hwm ua ntej noj mov. Yog tias tsim nyog, NovoMix 30 FlexPen tuaj yeem siv sijhawm luv luv tom qab noj mov. Qhov nruab nrab, tus neeg mob xav tau cov tshuaj insulin yog nyob ntawm lub cev qhov hnyav ntawm 0.5 txog 1.0 units / kg / hnub thiab tuaj yeem muab tag nrho lossis ib nrab los ntawm kev qhia ntawm cov tshuaj NovoMix 30 Flexpen. Cov kev xav tau txhua hnub rau insulin tuaj yeem nce ntxiv hauv cov neeg mob uas tiv thaiv nws (piv txwv, nrog kev rog) thiab txo qis hauv cov neeg mob uas muaj cov khoom seem muaj cov tshuaj insulin endogenous. NovoMix 30 FlexPen feem ntau yog pub rau sc rau thaj tsam ncej puab. Kev hno tuaj yeem ua tau nyob hauv thaj av ntawm thaj chaw ntawm sab xub ntiag lub plab, pob tw lossis pob txha leeg ntawm lub xub pwg. Txhawm rau kom tsis txhob lipodystrophy, qhov chaw txhaj tshuaj yuav tsum tau hloov txawm tias nyob hauv tib thaj chaw.

Zoo ib yam li lwm cov tshuaj insulin, lub sijhawm ua haujlwm yuav txawv raws qhov koob tshuaj, thaj chaw txhaj tshuaj, ntshav khiav nrawm, qhov ntsuas kub thiab qib ntawm lub cev. Qhov kev cia siab ntawm kev nqus ntawm cov tshuaj tso rau ntawm thaj chaw txhaj tshuaj tsis tau txheeb xyuas.

NovoMix 30 FlexPen tuaj yeem kho rau cov neeg mob ntshav qab zib hom II mob ntshav qab zib ua ob qho kev kho mob thiab ua ke nrog metformin hauv cov teeb meem no thaum cov piam thaj hauv ntshav tsis tuaj yeem tswj tau zoo siv cov tshuaj metformin nkaus xwb.

Qhov kev pom zoo xav kom pib ntawm NovoMix 30 FlexPen hauv kev sib xyaw nrog metformin yog 0.2 U / kg / hnub thiab yuav tsum tau hloov kho nyob ntawm tus neeg xav tau cov tshuaj insulin, suav raws cov ntshav qabzib.

Lub siab ua haujlwm lossis lub raum tsis zoo ua haujlwm tuaj yeem txo tus neeg mob txoj kev xav tau cov tshuaj insulin. Cov yam ntxwv ntawm kev nqis tes ntawm cov tshuaj NovoMix 30 Flexpen nyob rau hauv cov menyuam yaus hnub nyoog qis dua 18 xyoo tsis tau raug tshawb nrhiav.

NovoMix 30 FlexPen yog tsim rau kev txhaj tshuaj nkaus xwb. Cov tshuaj tsis tuaj yeem nkag mus rau hauv / hauv lossis ncaj qha rau hauv cov leeg. Txhawm rau kom tsis txhob tsim cov ntawv infiltrates, koj yuav tsum hloov tas mus li qhov chaw txhaj tshuaj. Cov chaw zoo tshaj plaws rau kev tswj hwm yog hauv ntej, phab ntsa plab, xub pwg, saum npoo ntawm ncej puab lossis xub pwg. Qhov kev ua ntawm insulin tshwm sim sai dua nrog kev qhia ntawm nws cov sc hauv lub duav.

Qhov ntau npaum li cas ntawm cov tshuaj tiv thaiv hormonal yuav tsum tau txiav txim siab tsuas yog txiav txim siab ib leeg, uas koom nrog kev teem caij los ntawm tus kws tshaj lij ntawm qee cov koob tshuaj, nyob ntawm qhov pom tseeb ntawm cov ntshav qab zib.

Muab tus nqi ntawm cov tshuaj ntawm lub cev, nws yog qhov pom zoo kom ua kom paub nws, raws li twb tau sau tseg, tam sim ua ntej noj zaub mov. Yog tias muaj qhov xav tau ntawd, tom qab ntawd cov tshuaj tiv thaiv hormonal yuav tsum tau qhia ntawm kev sib txuam luv tom qab noj zaub mov.

Yog tias koj taw tawm qee cov ntsuas nruab nrab, tom qab ntawd cov hom tshuaj tiv thaiv insulin yuav tsum tau siv nyob rau, tshwj xeeb, ntawm qhov nyhav ntawm cov ntshav qab zib. Tham txog qhov no, lawv tau them sai sai rau qhov tseeb tias nws yog txij li 0.5 txog 1 UNITS ib kg rau 24 teev.

Qhov kev xav tau yuav nce ntxiv rau cov neeg mob ntshav qab zib uas muaj qee qhov kev tawm tsam rau cov tshuaj tiv thaiv hormonal. Nws tuaj yeem txo qis nrog txuas ntxiv mus txuas ntxiv ntawm nws tus kheej hormonal feem.

P / c. Tsis txhob muab NovoMix® 30 Penfill® / FlexPen® iv vim qhov no tuaj yeem ua rau ua rau ntshav muaj ntshav qab zib siab heev. Kev tswj hwm i / m ntawm NovoMix® 30 Penfill® / FlexPen® tseem yuav tsum raug zam. Tsis txhob siv NovoMix® 30 Penfill® / FlexPen® rau subcutaneous insulin infusion (PPII) hauv cov tshuaj insulin.

Cov koob tshuaj NovoMix® 30 Penfill® / FlexPen® yog txiav txim los ntawm tus kws kho mob tshwj xeeb rau txhua kis, raws li tus neeg mob xav tau. Txhawm rau kom ua tiav qib siab ntawm glycemia, nws raug nquahu kom tswj cov concentration ntawm cov piam thaj hauv cov ntshav thiab kho qhov ntau ntawm cov tshuaj.

NovoMix® 30 Penfill® / FlexPen® tuaj yeem raug kho rau cov neeg mob ntshav qab zib hom 2 ntshav qab zib mellitus xws li kev kho mob monotherapy lossis sib xyaw nrog qhov ncauj tshuaj hypoglycemic hauv rooj plaub uas cov ntshav qabzib tsis txaus tsuas yog los ntawm cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj.

Rau cov neeg mob ntshav qab zib hom 2 uas yog thawj zaug tau txhaj tshuaj insulin, kev pom zoo pib siv ntawm NovoMix® 30 Penfill® / FlexPen® yog 6 ntu ua ntej noj tshais thiab 6 chav ua ntej noj hmo. Kev coj ntawm 12 pawg ntawm NovoMix® 30 Penfill® / FlexPen® ib zaug ib hnub nyob rau yav tsaus ntuj (ua ntej noj hmo) kuj tseem raug tso cai.

Hloov chaw ntawm tus neeg mob los ntawm lwm yam tshuaj insulin

Thaum hloov mus rau tus neeg mob los ntawm biphasic tib neeg cov tshuaj insulin rau NovoMix® 30 Penfill® / FlexPen®, ib qho yuav tsum pib nrog tib lub koob tshuaj thiab hom kev tswj hwm. Tom qab ntawv kho lub koob tshuaj raws li qhov xav tau ntawm tus neeg mob (saib

Hauv qab no yog cov lus qhia rau koob tshuaj titration). Raws li ib txwm muaj, thaum hloov tus neeg mob mus rau ib hom tshuaj insulin tshiab, kev tswj hwm kev tswj hwm nruj yog qhov tsim nyog thaum lub sijhawm hloov ntawm tus neeg mob thiab hauv thawj lub lis piam ntawm kev siv tshuaj tshiab.

Ntxiv dag zog NovoMix® 30 Penfill® / FlexPen® txoj kev kho yog tuaj yeem hloov los ntawm kev hloov pauv ntawm ib koob rau ib zaug. Nws raug nquahu tias tom qab tau txais 30 koob ntawm cov tshuaj hloov mus rau kev siv NovoMix® 30 Penfill® / FlexPen® 2 zaug hauv ib hnub, faib cov koob tshuaj ua ob feem sib luag - thaum sawv ntxov thiab yav tsaus ntuj (ua ntej noj tshais thiab noj hmo).

Txoj kev hloov mus rau kev siv NovoMix® 30 Penfill® / FlexPen® 3 zaug hauv ib hnub yog tau los ntawm kev faib cov koob tshuaj thaum sawv ntxov ua ob ntu sib luag thiab qhia ob ntu no thaum sawv ntxov thiab yav tav su (peb zaug noj ib hnub).

Txhawm rau kho qhov koob tshuaj NovoMix® 30 Penfill® / FlexPen®, cov ntshav qis tshaj plaws ntawm cov ntshav qabzib tau txais hauv peb hnub dhau los yog siv.

Txheeb xyuas qhov tsim nyog ntawm cov koob tshuaj dhau los, siv tus nqi ntawm cov concentration ntawm cov piam thaj hauv cov ntshav ua ntej noj mov tom ntej.

Koob kev hloov kho tuaj yeem nqa tawm 1 zaug hauv ib lub lis piam kom txog thaum lub hom phiaj nqi HbA1c tau mus txog. Tsis txhob nce qhov koob tshuaj ntawm cov tshuaj yog tias lub ntsej muag hypoglycemia tau pom nyob hauv lub sijhawm no.

Kev hloov koob tshuaj yuav tsim nyog thaum ua kom tus neeg mob lub cev ua si, hloov nws li kev noj zaub mov kom zoo, lossis muaj lub ntsej muag comorbid.

Txhawm rau kho qhov koob tshuaj NovoMix® 30 Penfill® / FlexPen®, cov lus pom zoo rau nws cov titration tau muab hauv qab no (saib Cov Lus 1).

Cov pab pawg neeg tshwj xeeb

Raws li ib txwm muaj, thaum siv cov tshuaj insulin, nyob rau hauv cov neeg mob ntawm cov pab pawg tshwj xeeb, cov ntshav qabzib concentration yuav tsum ua tib zoo tswj hwm thiab qhov tshuaj ntawm aspart ua rau tus kheej hloov kho.

Cov neeg laus thiab cov neeg laus. NovoMix® 30 Penfill® / FlexPen® tuaj yeem siv rau cov neeg mob laus, txawm li cas los xij, kev paub nrog nws siv nyob rau hauv kev sib xyaw nrog qhov ncauj tshuaj hypoglycemic hauv cov neeg mob laus dua 75 xyoo tau txwv.

Cov neeg mob uas lub raum tsis zoo thiab lub siab ua haujlwm. Hauv cov neeg mob uas lub raum lossis hepatic tsis txaus, qhov kev xav tau yuav tsum tau txo tshuaj insulin.

Menyuam yaus thiab tub ntxhais hluas. NovoMix® 30 Penfill® / FlexPen® tuaj yeem siv los kho cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog tshaj 10 xyoo thaum siv tshuaj pleev ua ntej. Cov ntaub ntawv kho mob tsawg tsawg muaj rau cov menyuam yaus 6–9 xyoo (saib Pharmacodynamics).

NovoMix® 30 Penfill® / FlexPen® yuav tsum tau txhaj tshuaj subcutaneously mus rau tus ncej puab lossis sab hauv plab phab ntsa. Yog tias qhov xav tau, cov tshuaj no tuaj yeem siv rau hauv xub pwg lossis pob tw.

Nws yog ib qho tsim nyog yuav tau hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical kom tiv thaiv kev txhim kho ntawm lipodystrophy.

Ib yam li lwm yam insulin npaj, lub sijhawm ua haujlwm ntawm NovoMix® 30 Penfill® / FlexPen® nyob ntawm qhov koob tshuaj, qhov chaw tswj, ntshav txaus, qhov kub thiab theem ntawm kev siv lub cev.

Piv rau tib neeg cov tshuaj insulin, biphasic, NovoMix® 30 Penfill® / FlexPen® pib ua kom nrawm dua, yog li nws yuav tsum tau siv tam sim ua ntej muaj kev txom nyem. Yog tias tsim nyog, NovoMix® 30 Penfill® / FlexPen® tuaj yeem tswj hwm tau sai tom qab noj cov neeg thov.

Kev tiv thaiv kev nyab xeeb

NovoMix® 30 Penfill® / FlexPen® thiab koob yog rau kev siv tus kheej nkaus xwb. Tsis txhob ntim roj ntxiv rau Penfill® cartridge / FlexPen® koob txhaj tshuaj lim.

NovoMix® 30 Penfill® / FlexPen® siv tsis tau yog tias tom qab sib tov nws tsis dhau los ua ib qho dawb thiab huab.

Tus neeg mob yuav tsum tau hais txog qhov yuav tsum tau sib tov NovoMix® 30 Penfill® / FlexPen ® tshem tawm tam sim ntawd ua ntej siv.

Tsis txhob siv NovoMix® 30 Penfill® / FlexPen® yog tias nws tau khov. Cov neeg mob yuav tsum tau ceeb toom kom tsis txhob muab rab koob tom qab txhua txoj kev txhaj tshuaj.

NovoMix® 30 Penfill®

- Yog hais tias tus neeg mob ua xua (hypersensitive) rau insulin aspart lossis ib qho twg uas ua NovoMix® 30 Penfill® (saib “Txheej Txheem”),

- yog hais tias tus neeg mob xav tias mus rau hauv lub cev tsis muaj ntshav qab zib (cov ntshav qab zib qis) (saib Hypoglycemia),

- rau PPII hauv cov tshuaj insulin,

- Yog hais tias lub cartridge los yog lub tshuab ntxig rau hauv daim cartridge uas tau nruab los yog poob qis los yog daim cartridge raug puas los yog tsoo,

- Yog tias qhov chaw cia khoom ntawm cov tshuaj tau txhaum cai lossis nws khov,

- Yog hais tias cov tshuaj insulin tsis dhau los ua xim dawb thiab huab tom qab sib tov,

- yog tias nyob rau hauv qhov kev npaj tom qab sib xyaw nws muaj cov lumps dawb lossis dawb lo lo rau hauv qab lossis phab ntsa hauv daim cartridge.

- kos daim paib kom paub tseeb tias hom tshuaj insulin raug xaiv,

- ib txwm kuaj xyuas daim cartridge, suav nrog lub roj hmab piston, tsis txhob siv daim cartridge yog tias nws pom kev puas tsuaj lossis qhov sib txawv nruab nrab ntawm lub piston thiab daim pluaj dawb ntawm daim cartridge pom, rau cov lus qhia ntxiv xa mus rau cov lus qhia rau kev siv lub system rau insulin administration,

- ib txwm siv rab koob tshiab rau txhua txoj kev txhaj tshuaj tiv thaiv kev kis mob,

- NovoMix® 30 Penfill® thiab rab koob yog rau kev siv tus kheej nkaus xwb.

NovoMix 30 Flexpen qhia rau cov ntshav qab zib. Pharmacokinetics tsis tau kawm hauv cov pawg no ntawm cov neeg mob:

neeg laus neeg laus
cov menyuam
cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm.

Categorically, cov tshuaj yuav tsum tsis txhob siv rau hypoglycemia, ntau rhiab heev rau cov tshuaj aspart lossis lwm qhov tshuaj ntawm cov tshuaj teev tseg.

Dosage NovoMix 30 Flexpen yog tus neeg nruj me ntsis thiab muab rau kev teem caij ntawm tus kws kho mob, nyob ntawm seb pom tseeb qhov xav tau ntawm tus neeg mob. Vim tias cov tshuaj nrawm heev, nws yuav tsum tau ua haujlwm ua ntej noj mov. Yog tias tsim nyog, insulin, nrog rau penfill, yuav tsum tau muab tshuaj sai sai tom qab noj mov.

Yog tias peb tham txog cov ntsuas nruab nrab, ces NovoMix 30 FlexPen yuav tsum thov raws li qhov hnyav ntawm tus neeg mob thiab yuav los ntawm 0.5 txog 1 UNIT rau txhua qhov hnyav ib hnub. Qhov kev xav tau yuav nce ntxiv nyob rau hauv cov neeg mob ntshav qab zib uas muaj kev tiv thaiv insulin, thiab txo qis thaum muaj qee qhov tshwj tseg cov pa tawm ntawm lawv tus kheej lawm.

Flexpen feem ntau yog tswj xyuas subcutaneously hauv tus ncej puab. Los tseem muaj peev xwm ua tau hauv:

tsam plab (sab xub ntiag phab ntsa),
pob tw
deltoid leeg ntawm lub xub pwg.

Lipodystrophy tuaj yeem zam tau tias cov chaw txhaj tshuaj yog cov kev hloov chaw.

Ua raws li cov piv txwv ntawm lwm yam tshuaj, lub sijhawm sib kis ntawm cov tshuaj kuj txawv. Qhov no yuav cia siab rau:

tsuas tshuaj
chaw txhaj tshuaj
ntshav txaus
theem ntawm kev siv lub cev
lub cev kub.

Qhov kev cia siab ntawm kev nqus ntawm cov tshuaj tso rau ntawm thaj chaw txhaj tshuaj tsis tau txheeb xyuas.

Cov neeg mob uas muaj ntshav qab zib hom 2, NovoMix 30 FlexPen (thiab mem tes ua piv txwv) tuaj yeem raug kho raws li kev kho mob tseem ceeb, nrog rau kev sib xyaw nrog metformin. Qhov tom kawg yog qhov tsim nyog nyob rau hauv cov xwm txheej uas tsis tuaj yeem txo qhov kev nqus ntawm cov ntshav qab zib los ntawm lwm txoj hauv kev.

Thawj qhov kev pom zoo ntawm cov tshuaj nrog metformin yuav yog 0.2 units ntawm ib phaus ntawm tus neeg mob lub cev ib hnub. Qhov ntim ntawm cov tshuaj yuav tsum tau kho nyob ntawm cov kev xav tau ntawm txhua kis.

Nws tseem yog ib qho tseem ceeb kom them rau qib ntawm cov piam thaj hauv ntshav cov ntshav. Ib qho ua tsis zoo lub raum lossis hepatic muaj nuj nqi yuav txo qhov kev xav tau cov tshuaj hormone.

NovoMix 30 Flexpen tsis tuaj yeem siv los kho menyuam yaus.

Cov tshuaj hauv cov lus nug tsuas yog siv tau rau ntawm kev txhaj tshuaj ib leeg xwb. Nws tsis tuaj yeem raug categorically txhaj rau hauv cov leeg nqaij lossis leeg ntshav.

- nce ib tug neeg rhiab rau insulin aspart lossis lwm yam tshuaj.

Nws tsis raug nquahu kom siv cov tshuaj no rau menyuam yaus hnub nyoog qis dua 6 xyoo, vim tias cov kev tshawb fawb soj ntsuam txog kev siv NovoMix® 30 FlexPen® tsis tau ua.

Lub siab ua haujlwm tsis zoo tuaj yeem ua rau txo qis ntawm cov tshuaj insulin.

Lub raum khiav tsis zoo tuaj yeem ua rau txo qis ntawm cov tshuaj insulin.

Cov tshuaj Novulinum insulin yog ib qho ntawm ntau yam tshuaj - hloov rau ntuj tsim insulin los ntawm tib neeg ua los ntawm cov txiav. Thaum koj tus kheej hormone tsis tsim txaus, koj yuav tsum nkag mus rau nws los ntawm sab nraud los ntawm kev txhaj tshuaj. Rau qhov no, Novomix tshuaj kuj tseem xav tau.

Tso tawm daim ntawv thiab cov tshuaj yeeb tshuaj

Soluble aspartate
Cov tshuaj tiv thaiv crystalline asparagus.

Lawv tsim ib ob-theem aspart. Cov khoom xa tuaj rau hauv daim ntawv ntawm homogeneous dawb (tsis muaj suav nrog) raug tshem tawm npaj rau kev txhaj tshuaj. Vim nws homogeneity, nws tsis cais, tsis ua ib qho nag lossis daus. Nrog lub caij nyoog mus ntev, txawm li cas los xij, floc tsim yog tau. Ib zaug ntxiv ua homogeneous nrog nplawm.

Cov Yuav Tsum Muaj

hypoglycemia, ua kom tsis txaus siab rau cov tshuaj insulin aspart lossis ib qho tshuaj hauv cov tshuaj

Novomix Flekspen tau txais txiaj ntsig zoo rau kev siv rau hauv kev txiav txim siab kom tshem tau cov mob muaj kab mob ntshav qab zib.

Pharmacokinetics, uas yog, qhov txiaj ntsig ntawm kev muaj pes tsawg leeg ntawm tib neeg lub cev, tsis tau kawm txog hauv pawg ntawm cov neeg mob xws li cov neeg laus, cov menyuam yaus, thiab cov neeg mob uas tau ua txhaum hauv kev ua haujlwm ntawm lub siab thiab lub raum tau tshawb pom yav dhau los.

Nws yog categorically tsis pom zoo kom siv cov tshuaj tiv thaiv hormonal rau hypoglycemia, kev paub ntau ntxiv ntawm kev raug rau cov tshuaj aspart, ntxiv rau lwm yam tshuaj los ntawm cov tshuaj tau tshaj tawm.

nce ib tug neeg mob nkag siab rau insulin aspart lossis ib yam ntawm cov tshuaj.

Nws tsis pom zoo rau cov menyuam yaus hnub nyoog qis dua 6 xyoo, raws li cov kev tshawb nrhiav kev tshawb fawb txog kev siv NovoMix® 30 Penfill® / FlexPen® tsis tau ua tiav.

Cov nqi thiab khoom siv

Los rau ntawm kev muag hauv daim ntawv ntawm daim cartridges ntawm 3 ml lossis 300 IU. Tseem suav nrog yog tus cwj mem txhaj rau tshuab uas coj kev teeb meem ntxig tau. Nws muaj peev xwm los ntsuas qhov tsuas tshuaj. Nws ua haujlwm thaum tsim cov tshuaj cartridge rau hauv nws. Koob rau txoj siv yog muas nyias.

Cov tshuaj Insulin Novomiks 30 flekspen tau muag hauv cov thawv ntawv cardboard, uas, ntxiv rau tus cwj mem thiab tus cartridge, suav nrog cov lus qhia rau kev siv cov khoom lag luam. Qhov tsawg kawg nkaus tus nqi ntawm cov tshuaj yog 1500 - 1600 rubles nyob rau hauv Moscow.

Insulin NovoMiks: koob tshuaj ntawm kev tswj hwm, tshuaj xyuas

Stabilizes qib qab zib kom ntev
Rov kho cov tshuaj insulin pancreatic

Cov tshuaj Insulin NovoMiks yog cov tshuaj suav tshuaj ntawm cov tshuaj analogues ntawm tib neeg cov suab thaj. Nws yog muab rau hauv kev kho mob ntshav qab zib mellitus, ob qho tag nrho cov tshuaj insulin-cov tub rog thiab hom tsis muaj tshuaj insulin. Ntawm lub sijhawm melon, tus kabmob kis mus rau txhua fab ntawm lub ntiaj teb, thaum 90% ntawm cov neeg mob ntshav qab zib raug mob los ntawm daim ntawv thib ob ntawm tus kabmob, tshuav 10% - los ntawm thawj daim ntawv.

Cov tshuaj insulin yog qhov tseem ceeb, nrog kev tswj hwm tsis txaus, kev cuam tshuam tsis zoo hauv lub cev thiab txawm tias tuag tshwm sim. Yog li, txhua tus neeg uas kuaj pom tus mob ntshav qab zib mellitus, nws tsev neeg thiab cov phooj ywg yuav tsum "muaj riam phom" nrog kev paub txog cov tshuaj hypoglycemic thiab insulin, nrog rau kev siv raug.

Tus txheej txheem ntawm kev ua ntawm cov tshuaj

Cov tshuaj insulin muaj nyob hauv Denmark ua daim ntawv ncua, uas yog ib qho hauv 3 ml cartridge (NovoMix 30 Penfill) lossis hauv 3 ml koob txhaj tshuaj (NovoMix 30 FlexPen). Qhov kev ncua yog cov xim dawb, qee zaum tsim cov plaub ya raws tau. Nrog kev tsim cov dej nag dawb thiab cov kua translucent saum nws, koj tsuas yog yuav tsum tau co nws, raws li tau hais hauv cov lus qhia txuas nrog.

Cov tshuaj ua haujlwm ntawm cov tshuaj yog soluble insulin aspart (30%) thiab cov muaju, ib yam li insulin aspart tiv thaiv (70%). Ntxiv rau cov khoom xyaw no, cov tshuaj muaj mentsis glycerol, metacresol, sodium hydrogen phosphate dihydrate, zinc chloride thiab lwm yam tshuaj.

10-20 feeb tom qab kev qhia ntawm cov tshuaj nyob rau hauv daim tawv nqaij, nws pib nws cov nyhuv hypoglycemic. Cov tshuaj insulin aspart khi rau cov tshuaj hormones receptors, yog li cov piam thaj yog nqus los ntawm cov kab mob hlwb thiab qhov kev txwv tsis pub los ntawm nws cov khoom tawm los ntawm lub siab tshwm sim. Qhov zoo tshaj plaws ntawm kev siv tshuaj insulin yog pom tom qab 1-4 teev, thiab nws cov nyhuv ntev li 24 teev.

Pharmacological cov kev tshawb fawb thaum sib txuas nrog cov tshuaj insulin nrog cov ntshav qab zib kom tsawg dua ntawm cov tshuaj tiv thaiv kab mob ntshav qab zib thib ob tau qhia tias NovoMix 30 ua ke nrog metformin muaj cov nyhuv hypoglycemic ntau dua li kev sib xyaw ntawm sulfonylurea thiab metformin derivatives.

Txawm li cas los xij, cov kws tshawb fawb tseem tsis tau sim cov nyhuv ntawm cov tshuaj rau cov menyuam yaus, cov tib neeg muaj hnub nyoog laus thiab kev txom nyem los ntawm kab mob siab ntawm lub siab lossis ob lub raum.

Cov lus qhia rau kev siv tshuaj

Tsuas yog tus kws kho mob muaj cai sau qhov tseeb ntawm cov tshuaj ntshav ntawm insulin, suav rau hauv qib theem ntawm cov piam thaj hauv cov ntshav ntawm tus neeg mob. Nws yuav tsum tau rov qab hais tias cov tshuaj no tau muab ob qho tib si nrog rau thawj hom kabmob thiab nrog kev kho tsis muaj txiaj ntsig ntawm hom thib ob.

Muab tias biphasic hormone ua haujlwm nrawm dua li tib neeg txoj kev loj hlob, nws feem ntau raug tswj ua ntej noj zaub mov, txawm hais tias nws tseem tuaj yeem tswj hwm tau sai tom qab tau xau nrog zaub mov.

Qhov ntsuas nruab nrab ntawm qhov xav tau ntawm tus mob ntshav qab zib hauv cov tshuaj hormones, nyob ntawm nws qhov hnyav (hauv qhov phaus), yog 0.5-1 ib yam ntawm ib hnub.Kev noj tshuaj txhua hnub tuaj yeem nce ntxiv nrog cov neeg mob insensitive rau cov tshuaj hormones (piv txwv, nrog kev rog) lossis txo qis thaum tus neeg mob muaj qee qhov tshwj xeeb ntawm cov tshuaj insulin.

Nws yog qhov zoo tshaj plaws rau kev txhaj tshuaj hauv thaj chaw hauv tus ncej, tab sis nws kuj tseem muaj peev xwm nyob hauv thaj chaw hauv plab ntawm lub pob tw lossis xub pwg. Nws tsis tsim nyog yuav daig rau tib qho chaw, txawm tias nyob hauv thaj chaw ib txwm.

Insulin NovoMix 30 FlexPen thiab NovoMix 30 Penfill tuaj yeem siv cov cuab yeej tseem ceeb los yog ua ke nrog nrog lwm cov tshuaj hypoglycemic. Thaum ua ke nrog metformin, thawj koob tshuaj hormone yog 0.2 units ntawm kev ua nyob ntawm ib phaus ib hnub.

Tus kws kho mob yuav tuaj yeem kwv yees cov tshuaj ntawm ob lub tshuaj no raws li kev ntsuas ntawm cov piam thaj hauv ntshav thiab cov yam ntxwv ntawm tus neeg mob. Nws yuav tsum raug sau tseg tias lub raum lossis lub siab ua haujlwm tsis zoo tuaj yeem ua rau txo qis qhov xav tau rau cov ntshav qab zib hauv insulin.

NovoMix yog muab cov tshuaj subcutaneously xwb (ntau ntxiv txog lub algorithm rau kev siv tshuaj insulin subcutaneously), nws yog nruj me ntsis txwv tsis pub ua kev txhaj tshuaj rau cov leeg nqaij lossis leeg ntshav. Txhawm rau kom tsis txhob tsim cov ntawv infiltrates, feem ntau nws yuav tsum hloov thaj chaw txhaj tshuaj. Kev txhaj tshuaj tuaj yeem tsim nyob rau hauv txhua qhov chaw tau hais tseg dhau los, tab sis cov nyhuv ntawm cov tshuaj tshwm sim ntau dhau los thaum nws qhia hauv thaj chaw duav.

Kev cuam tshuam nrog lwm yam tshuaj

Thaum tswj hwm NovoMix 30 cov tshuaj insulin, qhov tseem ceeb yuav tsum tau muab rau qhov tseeb tias qee cov tshuaj muaj feem cuam tshuam rau nws cov nyhuv hypoglycemic.

Cawv feem ntau ua rau cov suab thaj txo qis ntawm cov tshuaj insulin, thiab beta-adrenergic blockers npog cov cim qhia ntawm lub xeev hypoglycemic.

Ua raws li cov tshuaj siv ua ke nrog insulin, nws txoj haujlwm tuaj yeem nce ntxiv thiab txo qis.

Peb pom tias qhov kev txo qis ntawm cov tshuaj hormones yog thaum siv cov tshuaj hauv qab no:

sab hauv hypoglycemic tshuaj,
monoamine oxidase inhibitors (MAO),
angiotensin hloov mus ua enzyme (ACE) inhibitors,
tsis-xaiv beta-adrenergic blockers,
octreotide
anabolic tshuaj yuam
salicylates,
sulfonamides,
dej cawv.

Qee yam tshuaj ua rau txo cov dej num ntawm insulin thiab nce siab rau tus neeg mob xav tau nws. Xws li tus txheej txheem tshwm sim thaum siv:

cov thyroid hormones
glucocorticoids,
sympathomimetics
danazole thiab thiazides,
tshuaj tiv thaiv noj sab hauv.

Qee cov tshuaj feem ntau tsis sib haum nrog NovoMix insulin. Qhov no yog, ua ntej ntawm tag nrho cov, cov khoom muaj thiols thiab sulfites. Cov tshuaj tseem raug txwv tsis pub ntxiv rau txoj kev daws teebmeem. Siv cov tshuaj insulin nrog cov neeg sawv cev no tuaj yeem ua rau lub txim nyhav hnyav.

Tus nqi thiab tshuaj tshuaj

Txij li thaum cov tshuaj tsim tawm txawv teb chaws, nws tus nqi yog siab heev. Nws tuaj yeem yuav nrog cov tshuaj hauv lub tsev muag tshuaj lossis xaj online ntawm tus muag lub vev xaib. Tus nqi ntawm cov tshuaj yog nyob ntawm seb qhov kev daws teeb meem yog nyob rau hauv lub taub tshuaj los yog koob txhaj tshuaj thiab hauv lub ntim twg. Tus nqi sib txawv rau NovoMix 30 Penfill (5 daim cartridges rau ib pob) - los ntawm 1670 txog 1800 rubles Lavxias, thiab NovoMix 30 FlexPen (5 koob xaum ib pob) muaj tus nqi hauv qhov ntau ntawm 1630 txog 2000 Lavxias rubles.

Kev tshuaj xyuas ntawm cov neeg mob ntshav qab zib feem ntau uas tau txhaj tshuaj biphasic hormone yog qhov zoo. Ib txhia hais tias lawv hloov mus rau NovoMix 30 tom qab siv lwm yam insulins hluavtaws. Hauv qhov no, peb tuaj yeem paub qhov txawv xws li qhov zoo ntawm cov tshuaj kom yooj yim ntawm kev siv thiab txo qis dua qhov uas yuav muaj qhov tsis nco qab.

Tsis tas li ntawd, txawm hais tias cov tshuaj muaj ntau ntawm cov tshwm sim tsis zoo, lawv tsis tshua muaj tshwm sim. Yog li, NovoMix tuaj yeem raug suav hais tias yog ib qho tshuaj muaj kev vam meej kiag li.

Tau kawg, muaj kev txheeb xyuas hais tias nyob rau qee kis nws tsis haum. Tab sis txhua cov tshuaj muaj contraindications.

Cov tshuaj zoo sib xws

Thaum muaj kev kho kom haum tsis zoo rau tus neeg mob lossis ua rau muaj kev phiv, tus kws kho mob uas tuaj koom yuav hloov qhov kev kho mob. Txhawm rau ua qhov no, nws kho qhov tshuaj ntau npaum li cas los yog txawm ploj nws txoj siv. Yog li no, xav tau siv tshuaj nrog cov tshuaj zoo ib yam li hypoglycemic.

Nws yuav tsum raug sau tseg tias NovoMix 30 FlexPen thiab NovoMix 30 Penfill npaj tsis muaj cov analogues hauv cov khoom siv sib txuam - insulin aspart. Tus kws kho mob tuaj yeem sau tshuaj rau cov tshuaj uas muaj cov nyhuv zoo sib xws.

Cov tshuaj no yog muag los ntawm daim ntawv sau yuav tshuaj. Yog li, yog tias tsim nyog, kho tshuaj insulin, tus neeg mob yuav tsum sab laj nrog kws kho mob.

Cov tshuaj uas muaj cov nyhuv zoo xws li:

Humalog Mix 25 yog cov hluavtaws sib piv ntawm cov tshuaj hormones uas tsim los ntawm tib neeg lub cev. Lub ntsiab tivthaiv yog insulin lispro. Cov tshuaj kuj ua rau lub ntsej muag luv luv los ntawm kev tswj hwm cov ntshav qabzib thiab nws cov metabolism. Nws yog cov raug tshem tawm dawb, uas tawm hauv koob txhaj tshuaj hu ua cwj mem ceev. Tus nqi nruab nrab ntawm cov tshuaj (5 koob txhaj ntawm 3 ml ib) yog 1860 rubles.
Himulin M3 yog ib qho nruab nrab ntawm insulin uas tso tawm hauv kev ncua. Lub teb chaws ntawm kev tsim cov tshuaj yog Fabkis. Cov tshuaj nquag ntawm cov tshuaj yog tib neeg biosynthetic insulin. Nws ua hauj lwm zoo txo cov concentration ntawm cov piam thaj hauv cov ntshav yam tsis tau ua rau pib ntawm hypoglycemia. Hauv kev lag luam tshuaj Lavxias, ntau txoj kev siv tshuaj kho mob tuaj yeem muas tau, xws li Humulin M3, Humulin Tsis tu ncua lossis Humulin NPH. Tus nqi nruab nrab ntawm cov tshuaj (5 koob txhaj tshuaj ntawm 3 ml) yog sib npaug rau 1200 rubles.

Cov tshuaj niaj hnub tau nce siab, tam sim no cov tshuaj insulin yuav tsum tau ua ob peb zaug hauv ib hnub. Yooj yim syringe cwjmem pab txhawb cov txheej txheem no ntau zaus dhau mus. Kev ua lag luam pharmacological muab kev xaiv ntau ntawm ntau yam hluavtaws insulins. Ib qho ntawm cov tshuaj uas paub zoo yog NovoMix, uas txo cov ntshav qab zib kom muaj nuj nqis li qub thiab tsis ua rau cov ntshav qis. Nws siv kom zoo, nrog rau kev noj haus thiab ua si lub cev yuav ua kom lub neej ntev thiab tsis muaj mob rau cov ntshav qab zib.

Nta

Qhov kev npaj muaj ib qho sib xyaw ua ke ntawm cov tshuaj ntawm tib neeg cov tshuaj insulin, tau los ntawm kev tsim hluav taws xob, ntawm kev ua tau txawv ntau yam. 30% yog insulin aspart - yog ib qho tshuaj lom neeg uas ua tsis dhau 15 feeb tom qab kev tswj hwm. 70% yog daim qauv ntawm cov tshuaj hormones, uas, yog ib theem tsis txaus, muab cov kev ua haujlwm ntev ntev.

Vim tias pib sai ntawm cov nyhuv, qhov kev txhaj tshuaj yog nqa tawm tam sim ua ntej noj mov.

Qhov siab tshaj plaws tau tiav hauv 1-4 teev, thiab tag nrho lub sijhawm ua yog 18 teev (los ntawm 16 txog 24).

Kev ntsuas rau siv

Feem ntau ntawm cov neeg mob uas tau sau Novomix yog cov neeg mob ntshav qab zib hom 2 ntshav qab zib, leej twg lub hom phiaj glycemia thiab glycated hemoglobin tsis tiav los ntawm kev siv 2-3 ntsiav tshuaj ntawm cov tshuaj uas muaj suab thaj. Thaum twg lub cev qhuav dej vim qhov ua haujlwm ntev dhau los, kev teem sijhawm los ntawm cov tshuaj hormones los ntawm sab nraud coj cov metabolism hauv kev ua kom ze ze rau lub cev.

Ntawm hom 1 mob ntshav qab zib mellitus, cov tshuaj insulins sib xyaw ua ke tau sau tsawg dua vim tias qhov nyuaj ntawm kev kho qhov tshuaj tiv thaiv cov tshuaj tivthaiv ultrashort - kev ua haujlwm ntev kuj tseem nce, uas tuaj yeem ua rau lub qog ntshav qab zib. Nws yooj yim dua rau cov neeg mob hauv pawg no siv qhov pib bolus regimen ntawm cov tshuaj insulin.

Sab sij huam

Lub ntsiab tsis xav qhov tshwm sim, uas yog vim muaj cov tshuab ntawm kev ua ntawm cov tshuaj insulin, yog cov ntshav qab zib tsawg. Txhawm rau tiv thaiv cov mob no, cov koob tshuaj tau suav nrog suav cov zaub mov noj thiab tus naj npawb ntawm cov khob cij noj. Kev tshuaj xyuas cov ntshav qab zib kom tsis tu ncua yuav pab koj xaiv qhov zoo tshaj plaws uas tsis ua rau mob ntshav qab zib.

Ntawm cov kab ke muaj zog, kev tawm pob ua xua, neuropathies, tsis pom kev ib ntus, pom pob txha yog qee zaum pom.

Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!

Ua txhaum ntawm txheej txheem ntawm kev siv tshuaj insulin, lipodystrophy tuaj yeem txhim kho - cov roj ntsha subcutaneous rog. Kev txhaj tshuaj rau hauv cov chaw no yog qhov mob, thiab resorption ntawm cov tshuaj yog qhov nyuaj. Txhawm rau kom tsis txhob tshwm sim ntawm lipodystrophy, nws raug nquahu kom txhaj cov tshuaj insulin ntawm cov ntsiab lus sib txawv hauv thaj chaw, piv txwv li, txav mus ncig ntawm txoj hlab ntaws.

Cov lus qhia tshwj xeeb

Cov kev tshawb fawb txog kev nyab xeeb ntawm cov tshuaj thaum cev xeeb tub tau qhia tias nws tsis cuam tshuam dab tsi hauv cov menyuam hauv plab. Txawm li cas los xij, ua tib zoo xav txog kev hloov pauv hloov, nyob ntawm lub sijhawm thiab qhov xav tau ntau dua kev xaiv koob tshuaj, nws raug nquahu kom hloov mus rau qhov pib kho bolus insulin thaum lub sijhawm xeeb tub.

Thaum lub sijhawm pub mis, Novomix siv tag nrho, nws cov teebmeem zoo ib yam li cov teebmeem ntawm tib neeg cov insulin.

Hauv cov neeg mob laus, tsis muaj kev txwv rau kev siv. Nws yuav tsum tsuas yog coj mus rau hauv kev txiav txim siab tias hauv cov pab pawg hnub nyoog tshaj 65 xyoo, qeeb qeeb hauv kev nqus tshuaj thiab ib qho kev txhim kho tom qab tshwm sim tau.

Nyob rau ntawm qhov muaj mob ntev ntev ntawm daim siab thiab lub raum, ua rau txo qis hauv kev ua haujlwm ntawm cov kabmob, muaj qeeb ntawm kev tshem tawm cov khoom thiab nce ntxiv hauv nws cov concentration hauv cov ntshav cov ntshav. Nyob rau hauv cov teeb meem zoo li no, kev txo qis ntawm Novomix tej zaum yuav tsim nyog.

Kev sib koom tes tswj hwm ntawm qee cov tshuaj tuaj yeem txhim kho lossis ua rau cov kab mob tsis txaus los soj ntsuam. Qhov ncauj hypoglycemic, qee yam tshuaj tiv thaiv kev tiv thaiv kabmob, salicylates, mebendazole, tetracycline, clofibrate, ketoconazole, pyridoxine muab ib qho kev nyiam ntawm hypoglycemia.

Glucocorticoids, qhov ncauj tiv thaiv kab mob, thyroxine, tshuaj tiv thaiv kab mob, thiazides, heparin, morphine, nicotine txo cov hauj lwm zoo ntawm insulin.

Hloov los ntawm lwm cov insulin

Hloov cov tshuaj insulin, ntau dua, thiab txawm tias thaj chaw ntawm kev tswj hwm xav tau kev saib xyuas kev kho mob, yog li ntawd nws raug nquahu kom nyob hauv tsev kho mob lossis muaj lub sijhawm txuas xov tooj nrog koj tus kws kho mob.

Thaum hloov los ntawm cov tshuaj insulin zoo sib xws, cov koob tshuaj yuav tsis tas li ua ke nrog cov koob tshuaj uas tau muab yav dhau los, vim nws muaj peev xwm hloov ntau npaum li cas ntawm cov koob tshuaj thiab cov tshuaj siv rau ib hnub.

Nws yog tsis yooj yim sua kom pom qhov ua tiav kev sib txuam ntawm cov muaj pes tsawg leeg hauv ib qho kev npaj.

Ob-theem tshuaj insulins uas muaj tib neeg lossis cov tshuaj hormones zoo sib xws muaj cov nyhuv zoo xws li: Humulin MZ, Gensulin M30, Humalog Mix25, Insulin lispro biphasic, Insuman Komb25, Biosulin 30/70, Mikstard 30 NM.

Ntshav qab zib ua 10 xyoo. Ua ntej nws coj Metformin, ces Yanumet. Txawm hais tias kev kho mob, qab zib feem ntau sawv, thiab lub zeem muag pib ploj zuj zus. Tus endocrinologist hais kom ntxiv insulin. Kolya Novomiks Flekspen twb dhau los tau 2 xyoos, tau ua tiav zoo hauv kev tswj suab thaj thiab glycated hemoglobin.

Yakovleva P., tus kws kho mob endocrinologist:

Feem ntau hauv kuv kev coj ua kuv hais tawm cov tshuaj insulin biphasic. Kuv muab kev nyiam rau cov tshuaj zoo, vim hais tias txwv tsis pub nws nyuaj rau lav qhov ua tau tsim nyog. Qhov zoo ntawm Novomix yog qhov ua siab ntev rau cov neeg mob, tsis tshua muaj tshwm sim tsis zoo tshwm sim ntawm qhov tsis zoo. Cov lus qhia rau Novomix, nkag siab tau rau cov neeg mob, xyuas kom tseeb tias kev coj ntawm cov tshuaj thiab siab ua raws li kev kho mob.