Diabeton MV: cov lus qhia ua tiav rau kev siv, tshuaj xyuas cov neeg mob ntshav qab zib

Ntshav qab zib MV yog tshuaj siv dav dav hauv kev kho mob ntshav qab zib hom 2. Nws yog tshuaj feem ntau rau cov neeg mob ntshav qab zib tsis muaj qhov hnyav dhau thiab tshaj tawm ntawm cov ntaub so ntswg tiv thaiv cov tshuaj insulin, vim tias ntsiav tshuaj pab txhawb rau maj mam hnyav nce thiab txhawb cov txiav ua ke.

Cov tshuaj tsis nto npe ntawm cov tshuaj yog gliclazide. "Diabeton MV" yog lub npe kev lag luam ntawm cov tshuaj ntawm Fabkis lub tuam txhab pabcuam Servier, nws tau muab rau cov tshuaj nyob rau hauv lub tsev muag tshuaj ntawm daim ntawv nyiam, vim tias lawv muaj nqi ntau dua li cov kabmob generics (Diabinax, Glidiab, Diabefarma) uas tsim tawm los ntawm gliclazide.

Kab laum MV txhais tau tias Diabeton nrog kev hloov kho tso tawm thiab cov nquag ua haujlwm tsis pom tshwm sim nws tus kheej tam sim ntawd, tab sis thaum nruab hnub, nyob hauv ib feem.

Tus neeg tau txais txiaj ntsig ntawm Diabeton MV

Yog tias peb sib piv cov tshuaj nrog lwm cov qauv ntawm sulfonylurea series, tom qab ntawd thaum tsis tau tshaj tawm cov lus txhoj puab heev, nws cov hauj lwm zoo yuav siab dua.

Diabeton MV nti tawm zoo rov qab glycemic tshuav,
Glyclazide stimulates lub sijhawm 2 ntawm cov tshuaj hormones tso tawm, tam sim ntawd mus txog qhov siab kawg thaum tau txais cov khoom noj carbohydrates.
Cov tshuaj txo cov kev pheej hmoo ntawm thrombosis,

Nrog rau cov lus pov thawj zoo ntawm cov tshuaj, cov tshuaj kuj muaj qhov tsis zoo.

B ua lub luag haujlwm rau insulin ntau lawm yog depleted.
Rau 2-8 xyoo (nyob ntawm lub cev qhov hnyav, sai dua rau cov neeg nyias), tus mob ntshav qab zib muaj tus mob thib 2 kis tau tus mob ntshav qab zib hom 1 ntau dua.
Cov tshuaj tsis tshem tawm cov ntaub so ntswg ua kom tsis muaj zog rau cov insulin, tab sis rau qee yam txawm tias txhim kho nws.
Kev txhim kho glycemic profile tsis tuaj yeem lav qhov txhim kho ntawm cov neeg tuag los ntawm cov ntshav qab zib (raws li kev tshawb fawb los ntawm lub chaw nto moo thoob ntiaj teb ADVANCE).

Txhawm rau tsis txhob yuam kom lub cev xaiv ntawm cov teeb meem los ntawm cov txiav thiab kab mob ntawm lub plawv, cov ntsiav tshuaj yuav tsum tau pab los ntawm kev tswj hwm koj kev noj haus thiab cov leeg ua si.

Kev ua neej hloov kho kuj tseem yuav txo cov kev pheej hmoo mob plawv rau hauv kev ua kom muaj glycemia ntau dua, poob rau hauv cov ntshav siab, rog rog, thiab lipid metabolism tsis meej.

Kev piav qhia ntawm daim ntawv muaj pes tsawg leeg thiab noj tshuaj

Lub ntsiab ntawm cov mis yog gliclazide - ib cov tshuaj nrog hypoglycemic lub peev xwm, tus sawv cev ntawm sulfonylurea chav kawm ntawm cov tshuaj. Cov tshuaj muaj pes tsawg leeg ntxiv nrog kev ua kom ntev ntawm lactose monohydrate, maltodextrin, hypromellose, magnesium stearate, silicon dioxide.

Cov ntsiav tshuaj tuaj yeem txheeb xyuas tau los ntawm oval cov duab nrog cov kab sib faib thiab cov tsiaj ntawv luv "DIA 60" rau ntawm ib sab.

Cov tshuaj tau ntim rau hauv cov hlwv rau 15-30 daim, hauv ib lub thawv ntawv cardboard nrog rau cov lus qhia nws tuaj yeem muaj 1-4 daim hlau zoo li no.

Cov tshuaj kws kho mob muab tawm. Rau Diabeton MV, tus nqi tsis yog qhov kev siv nyiaj ntau tshaj plaws, rau 30 ntsiav tshuaj qhov nruab nrab ntawm 300 rubles yuav tsum tau them.Qhov tshuaj tsis nyob hauv daim ntawv teev npe ntawm cov tshuaj tiv thaiv kab mob ua ntej. Lub sijhawm tag sij hawm tshaj tawm los ntawm tus tsim khoom lag luam tsis pub ntau tshaj 2 xyoos. Cov tshuaj tsis tas yuav tshwj xeeb rau kev khaws cia.

Cov Tshuaj Hauv Tshuaj

Sulfonylurea tshuaj, uas suav nrog Diabeton MV, txhawb kev ua ub no ntawm lub txiav thiab nws lub hlwb b, uas tswj cov tshuaj insulin ntau lawm. Qeb ntawm kev kis tau ntawm cov tshuaj no yog nruab nrab, piv txwv li, Maninil ib txwm muaj kev txhoj puab heev.

Cov tshuaj yuav pab tau zoo nrog rau cov cim ntawm kev ploj ntawm kab mob ntawm lub txiav, thaum tsis muaj kev tawm tsam nws tsis muab qib ntawm insulin tsim nyog los them rau kev mob glycemia. Nrog rau tej theem ntawm kev rog, cov tshuaj tsis tau hais tawm lawm.

Diabeton MV rov qab ua thawj theem ntawm cov tshuaj insulin yog tias qhov poob qis hauv nws qhov kev ua tau zoo raug pom hauv lub cev. Hauv cov ntshav qab zib uas muaj hom mob 2, cov tshuaj pab txhim kho cov tshuaj insulin thaum ntxov thaum cov carbohydrates nkag mus rau hauv lub cev thiab rov kho theem ob ntawm lub voj voog.

Ntxiv nrog rau qhov kev lees paub tsawg dua hauv glycemic indices, kev noj tshuaj pab cuam tshuam rau kev noj qab haus huv ntawm cov hlab ntsha thiab cov ntshav khov hauv lub cev. Txo cov platelet adhesion (kev sib sau ua ke), nws txo txoj kev pheej hmoo ntawm vascular thrombosis, ntxiv dag zog rau lawv los ntawm sab hauv, muab kev tiv thaiv angioprotective.

Cov tshuaj cuam tshuam cawv algorithm yog ib qho kev ua ntu zus.

Kev txiav tawm ua ntej txhawb los tso tawm qhov tshuaj hormones rau hauv cov ntshav,
Tom qab ntawd cov theem pib ntawm insulin secretion tau simulated thiab rov qab,
Txhawm rau txo qhov tsim ntawm cov ntshav txhaws hauv cov hlab ntsha me, platelet sib sau ua ke yog txo,
Nyob rau hauv parallel, muaj qee cov nyhuv antioxidant.

Ib qho kev siv ntawm cov tshuaj muab ib qho zoo ntawm cov tshuaj glibenclamide ib hnub. Qib theem ntawm C-peptide thiab insulin yog tsim nyob rau hauv lub cev tsis tau ntxov dua tom qab 2 xyoos ntawm kev noj tshuaj tas li.

Cov Tshuaj Pharmacokinetics

Cov tshuaj yog nqus rau hauv lub plab zom mov tag nrho. Hauv cov ntshav, nws cov ntsiab lus accumulates maj dhau 6 lub sijhawm. Cov qib ua tiav tau ntev li 6 mus rau 12 teev. Kev hloov pauv rau ntau yam kabmob ntshav qab zib muaj tsawg.

Ib txhij nrog cov tshuaj, kev nqus ntawm cov zaub mov noj rau hauv lub cev tsis hloov pauv pharmacokinetic yam ntxwv ntawm gliclazide. Kev sib txuas lus nrog cov ntshav protein yog khaws cia ntawm 95%, Vd - txog 30 liv.

Gliclazide metabolism tshwm sim hauv lub siab, tsis muaj lub zog metabolites hauv cov hlab ntshav.

Lawv lub raum raug tshem tawm (nce txog 1% hauv tib qho). T1 / 2 ntawm gliclazide sib txawv li ntawm 12-20 teev.

Thaum cov koob tshuaj tau nce mus rau qhov siab tshaj plaws (120 mg), thaj chaw hauv qab kab cim ntawm kev sib raug zoo ntawm lub sijhawm thiab kev faib tawm nce rau hauv kev faib ncaj qha.

Kev ntsuas rau siv

Kev txhim kho tshiab ntawm cov tshuaj nrog lub txiaj ntsig ntev ntev tau tsim kho los kho cov glycemic profile thiab tiv thaiv kev mob ntshav qab zib (mob stroke, retinopathy, mob plawv, nephropathy, mob caj dab).

Nws yog tshuaj rau cov neeg mob ntshav qab zib nrog lub cev nyhav nrog hom 2 mob ntshav qab zib ntawm kev mob hnyav thiab mob hnyav uas tsis muaj cov tsos mob ntawm cov ntaub so ntswg tiv thaiv cov tshuaj insulin.

Nws kuj tseem siv los ntawm cov kis las los txhim kho qhov rhiab ntawm cov ntaub so ntswg mus rau insulin, uas ua kom nrawm nce ntxiv.

Raws li pib tshuaj rau tus mob ntshav qab zib, Diabeton MV tsis haum. Nws kuj tseem txaus ntshai dhau los sau cov tshuaj rau cov rog, txij li tus txiav, thiab yog li nws ua haujlwm ntawm nws qhov txwv, ua 2-3 qhov kev txwv ntawm cov tshuaj insulin uas tsis tuaj yeem tiv thaiv kev mob hnyav. Mob ntshav qab zib MV nyob rau hauv cov ntaub ntawv no muaj peev xwm txawm provoke kev tuag (los ntawm mob plawv).

Txhawm rau kawm txog kev sib raug zoo ntawm kev xaiv ntawm cov tshuaj xub thawj rau kev tswj hwm tus mob ntshav qab zib hom 2 thiab kev pheej hmoo ntawm kev tuag, kev kawm tshwj xeeb tau ua. Cov lus xaus yog pom tseeb.

Hauv cov neeg mob ntshav qab zib tau txais tshuaj sulfonylurea, piv nrog cov neeg tuaj yeem noj tshuaj metformin, qhov tshwm sim ntawm kev tuag los ntawm cov mob plawv yog 2 zaug ntau dua, mob plawv mob ntshav siab (CHD) yog 4.6 lub sijhawm siab dua, thiab ntshav hlab hlwb (NMC) yog 3 zaug.
Txoj kev pheej hmoo ntawm kev tuag los ntawm NMC thiab mob plawv ua rau muaj ntau dua rau cov neeg mob ntshav qab zib uas tau haus tshuaj raws li glibenclamide, glycvidone, glyclazide dua li cov uas tau kho nrog metformin.
Piv nrog rau cov pab pawg kho nrog glibenclamide, cov neeg koom nrog tau txais gliclazide qhia cov txiaj ntsig hauv qab no: ib qho txo 20% ntawm kev tuag tag nrho, thiab 40% txo kev tuag los ntawm UC thiab CCC.

Yog li, kev xaiv ntawm Diabeton MV ua tus thawj kab tshuaj, zoo li lwm yam tshuaj sulfonylurea, muaj feem yuav tuag nyob rau hauv 5 xyoo 2 zaug, khwv tau myocardial infarction - 4.6 zaug, mob hlwb - 3 zaug. Nrog cov mob ntshav qab zib uas nyuam qhuav soj ntsuam, metformin yog thawj txoj kev pabcuam khomob yog qhov kev xaiv zoo tshaj plaws.

Hauv kev ncaj ncees, nws yuav tsum raug sau tseg tias nrog peb lub xyoo lossis ntau dua ntawm kev haus ntshav qab zib MV, qhov kev pheej hmoo ntawm kev tau txais atherosclerosis tau txo qis. Lwm tus neeg sawv cev ntawm hom tshuaj no tsis tau muaj cov txiaj ntsig zoo sib xws. Lub antisclerotic muaj peev xwm ntawm Diabeton MV tuaj yeem piav qhia los ntawm qhov muaj nyob rau hauv nws cov muaj pes tsawg tus antioxidants uas tiv thaiv cov nqaij mos los ntawm oxidation.

Cov txiaj ntsig thiab mob loj ntawm Diabeton - hauv video:

Cov Yuav Tsum Muaj

Mob ntshav qab zib MV yog ib hom tshuaj tshiab tshiab nrog cov neeg ua haujlwm siab. Nws txawv ntawm tag nrho cov analogues ntawm sulfonylurea chav kawm ntawv nyob rau hauv cov nqe lus ntawm kev txhim kho ntawm cov teeb meem thiab ib feem pua tsawg ntawm cov kev mob tshwm sim.

Tab sis, zoo li ib yam tshuaj hluavtaws, gliclazide muaj ib tug xov tooj ntawm contraindications:

Cov siab nkag rau cov feem ntawm cov qauv thiab cov tshuaj sulfonylurea feem ntau,
Yam 1 ntshav qab zib
Cov mob ntshav qab zib ketoacidosis, tsis nco qab, thiab precoma,
Cov kab mob hnyav ntawm lub raum thiab nplooj siab, thaum hloov pauv mus rau insulin yog qhov yuav tsum tau ua.
Cev xeeb tub thiab lactation
Kho kho nrog miconazole,
Lub hnub nyoog txog 18 xyoo.

Cov tshuaj muaj lactose, yog li ntawd nws tsis yog qhia rau nws tsis txaus siab, rau cov ntshav qabzib-galactose malabsorption, galactosemia. Nws tsis pom zoo kom muab cov tshuaj danazol thiab phenylbutazone nrog Diabeton MV.

Cev xeeb tub

Tsis muaj kev paub dhau los hauv kev kho tus poj niam cev xeeb tub nrog gliclazide, nrog rau cov ntaub ntawv hais txog kev kho mob ntawm hom mob ntshav qab zib no nrog sulfonylurea cov tshuaj feem ntau.

Hauv kev sim rau cov poj niam tsiaj, qhov tshwm sim teratogenic ntawm gliclazide tsis tau tshwm sim.

Txhawm rau txo qis kev pheej hmoo ntawm kab mob plab yug me nyuam, yuav tsum tau tshuaj xyuas tas li thiab kev kho mob ntshav qab zib hom 2 xav tau. Qhov ncauj tshuaj qog ntshav hauv qhov ncauj tsis tau siv rau lub sijhawm no, cov poj niam cev xeeb tub tau pauv mus rau insulin thiab nws yog qhov zoo tshaj los ua qhov kev hloov pauv no txawm nyob rau theem ntawm kev npaj xeeb tub.

Tsis muaj cov ntaub ntawv hais txog kev nkag mus ntawm gliclazide mus rau niam mis, qhov txaus ntshai ntawm neonatal hypoglycemia tseem tsis tau tsim, vim li no, thaum kho nrog Diabeton MV, kev pub niam mis yog contraindicated.
Tsis muaj pov thawj rau kev ua haujlwm thiab kev nyab xeeb ntawm kev siv Diabeton MV rau cov menyuam yaus, yog li ntawd, rau cov neeg mob ntshav qab zib qis dua 18 xyoo, cov tshuaj kuj tsis tau sau tseg.

Sab sij huam

Diabeton MV muaj kev paub dhau los ntawm kev siv nrog qhov tsawg kawg ntawm kev sib txuam thiab cov kev mob tshwm sim, lub ntsiab yog qhov uas suav hais tias yog hypoglycemia, thaum lub ntsej muag glucometer nyeem poob qis dua cov phiaj.

Koj tuaj yeem paub qhov txawv xeev txaus ntshai los ntawm:

Mob taub hau thiab kiv taub hau,
Hma puas qab
Dyspeptic mob,
Poob lub zog, qaug zog,
Tawm hws ntau,
Kev mob siab rau lub plawv
Kev poob siab, zoo siab lub xeev, kev nyuaj siab,
Kev npau taws adrenergic, tshee hnyo,
Hais lus tsis meej, chov suab,
Pom kev tsis pom kev
Mob leeg pob txha
Tsis paub pab lub xeev, poob ntawm kev tswj hwm tus kheej,
Tsaus muag, tsis nco qab.

Nrog ib daim ntawv me me ntawm hypoglycemia, tus neeg raug muab qab zib, nrog rau daim ntawv hnyav, yuav tsum tau mus pw hauv tsev kho mob sai. Lub xeev ntawm hypoglycemia yog txaus ntshai thiab rov tshwm sim, yog li nws yog qhov tseem ceeb los tswj kev noj qab haus huv tom qab zoo los ntawm tus mob.

Los ntawm txoj kev, piv nrog cov Diabeton yooj yim, nws cov analogue (nrog qeeb tso tawm) tso cai rau koj faib cov teeb meem hauv lub cev ntau dua. Qhov no txo cov kev pheej hmoo ntawm hypoglycemia.

Ntxiv rau cov ntshav qog ntshav qab zib, muaj lwm qhov tsis pom tshwm sim:

Urticaria, ua pob ua xua, Quincke's edema,
Lub plab zom mov tsis zoo,
Cov kev mob hauv lub cev ua rau ntshav khov, ua kom cov ntshav dawb tsawg,
Pom ib ntus kev pom qhov tsis zoo vim qhov hloov ntawm glycemia, ntau zaus thaum hloov kho rau cov tshuaj,
Ntxiv kev ua haujlwm ntawm daim siab enzymes AST thiab ALT, hauv qee kis, kab mob siab.

Yog tias Diabeton MV tau raug siv es tsis txhob siv lwm yam tshuaj kho ntshav qab zib, nws yog ib qho tseem ceeb los saib xyuas glycemic rau ob lub lis piam los tiv thaiv qhov kev cuam tshuam ntawm cov teebmeem ntawm ob yam tshuaj phom sij rau hypoglycemia.

Thaum lub sijhawm kev sim kho mob ntawm lub chaw muaj npe zoo ADVANCE, ib qho tsis txaus ntseeg (los ntawm qhov kev xav tau ntawm qhov sib txawv) qhov sib txawv ntawm cov kev tswj hwm thiab pawg sim tau pom. Qhov ntau zaus thiab qhov mob ntawm cov hypoglycemia yog tsau tsawg. Feem ntau ntawm cov ntshav ntawm hypoglycemia tau sau tseg tiv thaiv keeb kwm ntawm kev kho txoj hauv txoj hauv kev nrog kev npaj cov tshuaj insulin.

Qhia Txog Tshuaj Yeeb

Txhim kho cov kev ua ntawm Diabeton MV miconazole (ob qho tib si hauv kev siv tshuaj thiab thiab siv sab nraud). Txoj kev sib xyaw ua ke yog nruj me ntsis, vim nws tuaj yeem ua rau mob ntshav qab zib.

Nws tsis pom zoo kom muab cov gliclazide nrog phenylbutazone. Nrog kev tswj hwm kev tswj hwm, hypoglycemic muaj peev xwm ntawm sulfonylurea derivatives yog txhim kho: kev tshem tawm yeeb tshuaj qeeb qeeb, phenylbutazone hloov chaw nws los ntawm cov protein ligament. Yog tias tsis muaj kev hloov pauv rau cov tshuaj, nws yog ib qho tsim nyog yuav tau kho qhov kev txhaj tshuaj ntawm gliclazide thiab ua tib zoo saib xyuas glycemia rau tag nrho lub sijhawm ntawm kev kho mob thiab tom qab qhov kawg.

Nce kev pheej hmoo ntawm glycemia ethanol thiab tshuaj raws nws. Rau lub sijhawm ntawm kev kho mob nrog Tus Mob Ntshav Qab Zib MV, nws yog ib qho tsim nyog yuav tsum tso tseg cov dej cawv thiab cov tshuaj raws dej cawv.

Kev sib xyaw nrog cov tshuaj tiv thaiv kab mob tau muab nrog kev ceev faj: insulin, biguanides, acarbose, diazolidinediones, GLP-1 antagonists, DPP-4 inhibitors, PP-blockers, MAO thiab ACE inhibitors, fluconazole, sulfonamide tshuaj, NP. Ib qho ntawm cov kev sib txuas ua ke nce qhov hypoglycemic muaj peev xwm ntawm Diabeton MV thiab xav tau koob tshuaj titration thiab saib xyuas qhov tseeb ntawm glycemic profile.

Nws tsis muaj zog lub peev xwm ntawm Diabeton MV Danazole, uas ua rau kom cov ntsiab lus ntawm cov suab thaj hauv ntshav. Nrog rau kev siv ncaj qha, dosage titration thiab glycemic xyuas yuav tsum muaj rau tag nrho chav kawm ntawm kev kho mob thiab tom qab nws. Qhov xwm txheej zoo sib xws tau pom nrog iv txhaj tshuaj b-adrenergic agonists.

Glyclazide + chlorpromazine complexes yog kho nrog ceev faj. Hauv kev txhaj tshuaj ntau, cov tshuaj tiv thaiv kab mob txo qis insulin ntau lawm, pab kev txuam nrog cov piam thaj hauv cov ntshav ntawm cov ntshav. Nws yog qhov tsim nyog los laij cov tshuaj ntau npaum li cas.

GCS thiab tetracosactide nrog rau txhua txoj hauv kev thov (pob qij txha, tawv nqaij, lub ntsaum tawm tswv yim) nce ntshav qab zib, ua rau ketoacidosis tshwm sim, uas txo qis kev kam rau cov khoom lag luam carbohydrate. Nyob rau thawj theem ntawm kev kho mob, maj mam koob ib feem kaum thiab kev saib xyuas ntawm cov glucometer tsis tsim nyog rau tag nrho lub sijhawm ntawm kev sib koom tes thiab tom qab ua tiav.

Txoj kev siv

Txog Cov Kab Mob Ntshav Qab Zib MV, cov lus qhia rau kev siv pom zoo tias cov neeg mob ntshav qab zib noj tshuaj thaum sawv ntxov, nrog rau noj tshais. Ib yam li txhua yam tshuaj tiv thaiv kev tiv thaiv kab mob, tus endocrinologist xaiv cov koob tshuaj tus kheej, suav txog qhov tshwm sim ntawm kev tshuaj ntsuam, theem ntawm ntshav qab zib, kab mob sib kis, lub cev tawm tsam cov tshuaj.

Thaum ib koob tshuaj twg (ntawm 30 txog 120 mg, uas yog 0.5-2 ntsiav tshuaj), noj gliclazide yog ib leeg. Yog tias lub sijhawm tau tawg, muab ob npaug rau noj yog qhov txaus ntshai - lub cev xav tau lub sijhawm los nqus tag nrho, yam tsis muaj kev xav tsis zoo, qhov tsis tuaj yeem.

Hauv qhov qauv txheem, qhov pib tshuaj yog Ѕ rooj. (30 mg). Rau cov ntshav qab zib ntawm lub hnub nyoog paub tab, koob tshuaj feem ntau tsis tsim nyog.

Yog tias qhov kev cai zoo li no muab kev tswj tiav glycemia, nws tuaj yeem siv los ua kev kho mob. Nrog kev tswj tsis tau zoo, qhov tshuaj kho tau kho, nqa cov txheej txheem txhua hnub rau 60.90 thiab txawm 120 mg. Koob txheej titration yog nqa tawm tom qab 30 hnub - nws yuav siv sij hawm ntau heev los soj ntsuam qhov ua tau zoo ntawm qhov xaiv xaiv.

Yog tias tus mob ntshav qab zib tsis muaj kev hloov pauv hauv 2 lub lis piam rau qhov zoo dua, kev suav nrog yog ua tau tsis pub dhau ib nrab ib hlis. Qhov siab tshaj uas tau tso cai kho tshuaj ntawm gliclazide yog 120 mg.

Yog tias cov ntshav qab zib tau pauv los ntawm cov kab mob ntshav qab zib Diabeteson nrog kev tso tawm sai sai ntawm gliclazide mus rau ib qho tshuaj tiv thaiv ntev, tom qab ntawv 80 mg Diabeton ntsiav tshuaj tuaj yeem hloov nrog cov koob tshuaj zoo sib xws nrog lub siab ntev ntawm 60 mg lossis 30 mg.

Thaum hloov lwm txoj kev kho mob glycemic nrog Diabeton MV, kev kho mob yav dhau los thiab lub sijhawm rau kev tshem tawm cov tshuaj yog muab rau hauv tus account.Feem ntau tsis tas yuav tsum muaj kev sib hloov ua ntu zus. Qhov pib noj tshuaj yog txiav txim siab ntawm 30 mg nrog kev kho me ntsis yog tias qhov tshwm sim ntawm kev kho tsis zoo.

Yog tias T1 / 2 ntawm cov tshuaj dhau los ntev, thiaj li yuav zam tau qhov kev cuam tshuam ntawm kev cuam tshuam uas ua rau lub plawv tsis muaj zog, yuav tsum tau txais ib qho ntawm qhov kev kawm. Lub hauv paus pib ntawm Diabeton MV kuj tseem sau ntawv yam tsawg kawg - 30 mg nrog tau muaj ntxiv titration.

Diabeton MV tuaj yeem siv hauv kev kho mob nyuaj. Txhawm rau txhim kho hypoglycemic muaj peev xwm siv insulin, biguanides, b-glucosidase inhibitors. Yog tias qhov ua tsis tiav, cov koob tshuaj insulin tau teev tseg.

Cov lus pom zoo ntxiv

Cov neeg mob ntshav qab zib nrog lub raum pathologies nyob rau hauv daim ntawv me thiab mob nyhav tsis pom zoo rau koob tshuaj feem ntau, nws tsuas yog ib qho tseem ceeb los soj ntsuam glycemia thiab lub raum kev ua tau zoo.

Kev saib xyuas tshwj xeeb yog yuav tsum tau los ntawm cov neeg mob uas muaj kev pheej hmoo nrog cov zaub mov tsis muaj calorie, ua haujlwm tsis txaus lub cev, endocrine pathologies (adrenal thiab pituitary tsis txaus, hypothyroidism, tshem tawm corticosteroids tom qab siv ntev lossis siv tshuaj ntau, CVD hnyav ntawm kev mob atherosclerosis lossis mob hlab plawv). Qhov kev mob ntshav qab zib no yog yam tsawg kawg nkaus uas yog kho tus mob ntshav qab zib MV - 30 mg.

Txhawm rau kom tau txais 100% qhov tshwm sim, qhov koob tshuaj tuaj yeem nce ntxiv rau 120 mg / hnub. Ib qho yuav tsum tau ua ua ntej yuav yog kev hloov kho lub neej - hloov mus rau kev noj zaub mov kom tsawg, ua kom lub cev qoj ib ce, thiab tswj lub xeev kev xav.

Yog tias tsim nyog, koj tuaj yeem ntxiv tshuaj kho mob nrog Diabeton MV metformin, insulin, thiazolidinediones. Hauv qhov no, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov muaj cov kev mob tshwm sim ntawm txhua qhov kev siv tshuaj thiab lawv sib cuam tshuam. Ua ntej tshaj plaws, peb tab tom tham txog kev pheej hmoo ntawm lub qog ntshav qab zib.

Pab nrog overdose

Qhov phom sij tseem ceeb ntawm kev noj ntau tshaj yog qhov mob hypoglycemic. Nrog rau cov tsos mob me thiab muaj kev tswj hwm tus kheej, nws yog qhov tsim nyog los txo cov qog ntawm Diabeton MV thiab lwm yam tshuaj tiv thaiv kab mob, kho cov khoom noj kom tau cov ntsiab lus tsis zoo. Saib xyuas kev noj qab haus huv ntawm tus mob ntshav qab zib yog qhov tseem ceeb kom txog thaum tus mob glycemia tiav kiag li, vim kev rov huam mob dua nyob hauv cov xwm txheej no.

Yog tias pom cov tsos mob glycemic muaj tseeb tshaj thiab qhia tseeb kev hem thawj rau kev noj qab haus huv, tshwj xeeb tshaj yog tias tus neeg mob tsis nco qab, nyob hauv txoj kev tsis nco qab, nrog rau qhov mob chua leeg, yuav tsum tau kho mob sai, tom qab mus pw hauv tsev kho mob. Thaum pib lub sijhawm zoo tshaj plaws, cov ntshav qab zib yuav tsum tau txhaj tshuaj rau cov ntshav nrog 50 ml ntawm cov piam thaj.

Txhawm rau kom muaj kev sib npaug (saum toj 1 g / l) - kuj muaj 10% kev daws teeb meem. Kev soj ntsuam ntawm txhua qhov ntsuas tseem ceeb tau ua nrog tsawg kawg 48 teev. Txij li thaum gliclazide nquag khi rau cov ntshav protein, hemodialysis nyob rau hauv rooj plaub no yog qhov tsis muaj txiaj ntsig.

Kuv yuav hloov li cas hloov ntshav qab zib MV

Tus thawj MV Diabeton, uas yog tsim los ntawm Fabkis lub tuam txhab Servier, muaj txaus pheej yig analogues raws li gliclazide, tab sis cov kev mob tshwm sim ntawm cov tshuaj no tuaj yeem hais tawm ntau dua, yog li thaum xaiv koj yuav tsum tsom tsis zoo rau tus nqi xwb, tab sis kuj pom zoo cov lus pom zoo ntawm tus kws kho mob tuaj koom.

Cov tsev muag tshuaj tuaj yeem muab cov tshuaj generics rau koj:

RDiabefarm, Glyclazide, Glucostabil, Glidiab,
Czech Gliklad,
Yugoslavian Predian thiab Glioral,
Indian Diabinax, Diatiku, Reklid, Glisid.

Yog tias gliclazide-based cov khoom lag luam tsis haum, tus endocrinologist yuav xaiv:

Cov tshuaj ntawm sulfonylurea series raws li glibenclamide, glycvidone, glimepiride,
Cov tshuaj ntawm cov chav kawm sib txawv, tab sis nrog tib lub tshuab ntawm kev txiav txim siab, piv txwv li NovoNorm los ntawm cov chav kawm av nplaum,
Cov tshuaj uas muaj txiaj ntsig zoo ib yam li Januvia lossis Galvus (DPP-4 inhibitors).

Glidiab MV lossis Diabeton MV: dab tsi yog qhov zoo tshaj plaws rau qee tus neeg mob tsuas yog txiav txim los ntawm tus kws kho mob. Cov ntaub ntawv yog muab rau kev hais dav dav, thiab tsis yog rau kev tshuaj xyuas tus kheej thiab kev tswj hwm tus kheej ntawm cov tshuaj muaj mob loj.

Dab Tsi Mob Ntshav Qab Zib MV Cov Ntshav Qab Zib Xav Txog

Txog Tus Mob Ntshav Qab Zib MV, kev tshuaj xyuas cov mob ntshav qab zib yog qhov tsis txaus siab: qab zib pab tswj hwm, tab sis ob peb tus neeg tswj hwm kom tsis txhob muaj qhov tsis txaus siab xav tau. Qhov kev ntshai tshaj plaws yog qhov tseeb hais tias tom qab cov tshuaj zoo li no, yuav luag txhua tus hloov mus rau tshuaj insulin - qee yam ua ntej, qee zaum tom qab.

Mob ntshav qab zib MV tsis yog kws kho mob rau cov neeg mob ntshav qab zib los ntawm txhua tus neeg mob ntshav qab zib, tab sis txawm tias cov neeg uas haum rau cov tshuaj yuav tshwm sim kev quav tshuaj rau cov tshuaj. Vim tias kev noj tshuaj tsis tsim nyog lossis tsis ua raws li lub sijhawm tswj hwm, qhov ua tau ntawm cov tshuaj yuav tsis raug rau cov lus tshaj tawm.

Nrog rau qhov ua kom mob ntshav qab zib ntau dhau, txawm tias muaj zaub mov noj kom tsawg thiab ua kom ib ce muaj zog, yuav tsum tau siv lwm txoj hauv kev kho kom zoo. Muaj ntau yam nuances, yog tias koj tau tso npe Diabeton MV, kawm cov lus qhia no kom paub tseeb tias kev teem caij tau kho kom raug.

Cov ntaub ntawv ntxiv txog Ntshav Qab Zib MV - hauv video:

Kev Siv Cov Tshuaj Ntshav Qab Zib

Cov tshuaj Diabeteson hauv cov ntsiav tshuaj uas pom zoo thiab hloov kho tawm (MV) raug tso cai rau cov neeg mob ntshav qab zib hom 2, uas kev noj haus thiab kev tawm dag zog tsis tswj tus kab mob tau zoo txaus. Cov tshuaj ua haujlwm nquag ntawm cov tshuaj yog gliclazide. Nws belongs rau cov pab pawg ntawm sulfonylureas. Gliclazide stimulates pancreatic beta hlwb tsim tawm thiab paim insulin ntau dua rau hauv cov ntshav, yam tshuaj uas ua kom qab zib.

Nws raug nquahu ua ntej ntawm txhua tus los kho mob ntshav qab zib hom 2 cov neeg mob tsis yog mob ntshav qab zib, tab sis cov tshuaj metformin - Siofor, Glyukofazh lossis Gliformin npaj. Kev noj tshuaj ntawm cov metformin yog maj mam nce los ntawm 500-850 txog 2000-3000 mg ib hnub. Thiab tsuas yog tias qhov kev daws teeb meem no tau txo qab qab zib tsis txaus, sulfonylurea derivatives tau ntxiv rau nws.

Ntau tus kws kho mob tau sau ntawv kho mob ntshav qab zib MV es tsis txhob siv cov tshuaj metformin rau lawv cov neeg mob. Txawm li cas los xij, qhov no tsis raug, tsis ua raws li cov lus pom zoo hauv nom tswv. Gliclazide thiab metformin tuaj yeem ua ke. Kev siv ua ke ntawm cov tshuaj no feem ntau tso cai rau koj kom tus neeg mob ntshav qab zib li qub qab zib rau ob peb xyoos.

Gliclazide hauv kev ntxiv cov ntsiav tshuaj tso tawm ua haujlwm ib yam rau 24 teev. Txog rau hnub no, cov qauv kev kho mob ntshav qab zib pom zoo kom cov kws kho mob sau ntawv rau Diabeton MV rau lawv cov neeg mob ntshav qab zib hom 2, tsis yog cov sulfonylureas yav dhau los. Saib, piv txwv, cov ntawv sau "Cov txiaj ntsig ntawm DYNASTY txoj kev kawm (" Diabeton MV: kev soj ntsuam ntawm cov neeg mob ntshav qab zib hom 2 uas muaj mob ntshav qab zib ") hauv phau ntawv journal" Teeb meem ntawm Endocrinology "No. 5/2012, sau phau ntawv M. V. Shestakova, O K. Vikulova thiab lwm yam.

Tus mob ntshav qab zib MV ua rau nws cov ntshav qab zib qis. Cov neeg mob zoo li nws yooj yim mus noj ib hnub ib zaug. Nws ua kom muaj kev nyab xeeb ntau dua li cov tshuaj qub - sulfonylurea derivatives Txawm li cas los xij, nws muaj qhov tsis zoo, vim tias nws zoo dua rau cov neeg mob ntshav qab zib kom tsis txhob noj. Nyeem hauv qab no qhov dab tsi yog qhov mob ntawm Diabeton, uas npog tag nrho nws cov zoo. Lub Diabet-Med.Com lub vev xaib txhawb txoj kev kho mob zoo rau hom ntshav qab zib hom 2 yam tsis muaj tshuaj kho mob.

Kev kho mob ntshav qab zib hom 2: cov txheej txheem ib qib zuj zus - tsis muaj kev tshaib plab, tshuaj phem thiab cov tshuaj insulin
Siofor thiab Glucofage ntsiav tshuaj - metformin
Li cas los kawm kom txaus siab rau kev kawm siv lub cev

Qhov zoo thiab qhov tsis zoo

Kev kho mob ntshav qab zib hom 2 nrog kev pab los ntawm cov tshuaj Diabeton MV muab tau txiaj ntsig zoo nyob rau lub sijhawm luv luv:

cov neeg mob tau txo cov ntshav qab zib kom tsawg,
txoj kev pheej hmoo ntawm hypoglycemia tsis yog ntau dua 7%, uas yog ntau dua qis dua rau lwm yam sulfonylurea derivatives,
nws yooj yim rau noj cov tshuaj ib hnub ib zaug, yog li cov neeg mob tsis txhob muab kev kho mob,
thaum noj cov tshuaj gliclazide hauv cov ntsiav tshuaj tso tawm ntev, tus neeg mob lub cev qhov hnyav yog nce me ntsis.

Diabeton MB tau dhau los ua cov tshuaj mob ntshav qab zib hom 2 vim nws muaj qhov zoo rau cov kws kho mob thiab nws yooj yim rau cov neeg mob. Nws yog ntau lub sijhawm yooj yim dua rau cov kws kho mob endocrinologist kom muab tshuaj noj dua li txhawb cov neeg mob ntshav qab zib kom ua raws li kev noj haus thiab kev tawm dag zog. Cov tshuaj sai sai txo cov suab thaj thiab zoo tiv thaiv. Tsis pub ntau dua 1% ntawm cov neeg mob yws ntawm cov kev mob tshwm sim, thiab txhua tus so txaus siab.

Qhov tsis zoo ntawm cov tshuaj Diabeton MV:

Nws ua kom nrawm nrawm rau kev tuag ntawm pancreatic beta hlwb, vim tias tus kab mob no hloov mus rau mob ntshav qab zib hom 1 ntau dua. Qhov no feem ntau tshwm sim ntawm 2 txog 8 xyoo.
Hauv cov neeg yuag thiab nyias, cov mob ntshav qab zib insulin feem ntau ua tshwj xeeb tshaj yog sai sai - tsis pub dhau tom qab 2-3 xyoos.
Nws tsis tshem tawm qhov ua rau mob ntshav qab zib hom 2 - txo qis rhiab ntawm cov hlwb rau insulin. Qhov teeb meem metabolic no yog hu ua insulin tsis kam. Noj Cov Ntshav Qab Zib yuav tuaj yeem ntxiv dag zog nws.
Lowers ntshav qab zib, tab sis tsis qis qis tuag. Qhov no tau lees paub los ntawm kev soj ntsuam thoob ntiaj teb loj heev los ntawm ADVANCE.
Cov tshuaj no tuaj yeem ua rau ua rau ntshav muaj ntshav qab zib. Muaj tseeb, nws qhov ntau yam tsawg dua yog tias lwm qhov sulfonylurea derivatives tau coj. Txawm li cas los xij, mob ntshav qab zib hom 2 tuaj yeem tswj tau yooj yim yam tsis muaj kev phom sij rau ntshav qab zib.

Cov tub txawg txij xyoo 1970 tau paub tias sulfonylurea derivatives ua rau kev hloov pauv ntawm cov ntshav qab zib hom 2 mus rau kev mob ntshav qabzib-hom ntshav qab zib hom 1 ntau. Txawm li cas los xij, cov tshuaj no tseem tseem tau sau tseg tshuaj. Qhov laj thawj yog tias lawv tshem tawm lub nra ntawm cov kws kho mob. Yog tias tsis muaj tshuaj txo cov ntshav qab zib, tom qab ntawd cov kws kho mob yuav tsum sau cov kev noj haus, kev tawm dag zog, thiab tshuaj insulin rau txhua tus mob ntshav qab zib. Qhov no yog ib txoj haujlwm nyuaj thiab tsis ua cas. Cov neeg mob coj tus cwj pwm zoo li tus neeg vwm Pushkin: "Nws tsis yog qhov nyuaj rau kev dag ntxias kuv, Kuv zoo siab los dag kuv tus kheej." Lawv kam noj tshuaj, tab sis lawv tsis nyiam ua raws kev noj haus, qoj ib ce, thiab ntau dua li yog li txhaj tshuaj insulin.

Mob ntshav qab zib MV - noj tshuaj tsis zoo. Txawm li cas los xij, sulfonylurea derivatives ntawm cov cim yav dhau los tseem phem dua. Cov kev tsis zoo uas tau teev tseg saum toj saud, lawv tau nrov tshaj. Mob ntshav qab zib MV tsawg kawg tsis cuam tshuam rau kev tuag, thaum lwm yam tshuaj nce ntxiv. Yog tias koj tsis npaj hloov mus rau txoj hauv kev ntuj rau kev kho mob ntshav qab zib hom 2, tom qab ntawd tsawg kawg yog hloov kho tso tawm (MV) ntsiav tshuaj.

Kev cuam tshuam ntawm kev mob ntshav qab zib rau tus kab mob ntshav qab zib ua rau pancreatic beta hlwb tsis ua rau muaj kev txhawj xeeb txog qhov endocrinologist thiab lawv cov neeg mob. Tsis muaj luam tawm hauv kev sau ntawv kho mob txog qhov teeb meem no. Qhov laj thawj yog hais tias feem ntau cov neeg mob uas muaj ntshav qab zib hom 2 tsis muaj sij hawm los muaj sia nyob ua ntej lawv pib tsim muaj cov ntshav qab zib insulin. Lawv lub plawv mob ua rau lub ntsej muag tsis muaj zog dua li cov kab mob pancreas. Yog li ntawd, lawv tuag los ntawm kev mob plawv lossis hlab ntsha tawg. Kev kho mob ntshav qab zib hom 2 raws li cov zaub mov uas tsis muaj carbohydrate ntau ib txhij ua rau cov piam thaj, ntshav siab, kuaj cov ntshav muaj roj thiab lwm yam kev phom sij.

Soj ntsuam kev soj ntsuam

Kev soj ntsuam tseem ceeb ntawm cov tshuaj Diabeton MV yog txoj kev tshawb nrhiav ADVANCE: Kev Ua Hauv Ntshav Qab Zib thiab VAscular -
preterax thiab Diamicron MR Tshuaj Ntsuam Xyuas. Nws tau tsim tawm xyoo 2001, thiab cov txiaj ntsig tau tshaj tawm nyob rau xyoo 2007-2008. Diamicron MR - raws li lub npe no, glyclazide hauv kev hloov kho cov ntsiav tshuaj yog muag hauv cov teb chaws Askiv. Nov yog tib yam li tshuaj Diabeton MV. Preterax yog hom tshuaj ua ke rau kev kub siab, cov khoom xyaw nquag uas yog indapamide thiab perindopril. Hauv cov tebchaws hais lus Lavxias, nws raug muag hauv qab lub npe Noliprel. Txoj kev tshawb no koom nrog 11,140 cov neeg mob uas muaj ntshav qab zib hom 2 thiab ntshav siab. Cov kws khomob raug saib xyuas nyob hauv 215 chaw kho mob hauv 20 lub tebchaws.

Tus mob ntshav qab zib MV txo qis ntshav qab zib, tab sis tsis txo kev tuag ntawm cov neeg mob ntshav qab zib hom 2.

Raws li cov txiaj ntsig ntawm txoj kev tshawb fawb, nws tau muab tawm tias cov ntsiav tshuaj siab rau cov neeg mob ntshav qab zib hom 2 txo cov zaus ntawm cov hlab plawv teeb meem li 14%, mob raum - los ntawm 21%, lub neej tuag - los ntawm 14%. Tib lub sijhawm, Diabeton MV txo qis cov ntshav qab zib, txo cov zaus ntawm ntshav qab zib nephropathy los ntawm 21%, tab sis tsis cuam tshuam rau lub neej tuag. Lavxias-lus los ntawm cov lus - tsab xov xwm “Qhia kev kho mob rau cov neeg mob ntshav qab zib hom 2 mob ntshav qab zib: cov txiaj ntsig ntawm qhov kev tshawb pom ADVANCE” hauv phau ntawv Journal System Cov Kev Ntshav Qeb No. 3/2008, sau Yu. Lub hauv paus qub - “Pab Pawg Sib Koom Tes ADVANCE. Kev tswj ntshav qabzib ntau ntxiv thiab cov kev mob ntshav siab rau cov neeg mob ntshav qab zib hom 2 "nyob rau hauv phau ntawv Xov Xwm New England Journal of Medicine, 2008, No. 358, 2560-2572.

Cov neeg mob uas muaj ntshav qab zib hom 2 tau raug xaj kom txo cov ntshav qab zib thiab cov tshuaj insulin yog tias noj zaub mov zoo thiab tawm dag zog tsis muab cov txiaj ntsig zoo. Qhov tseeb, cov neeg mob tsuas yog tsis xav ua raws li kev noj zaub mov kom tsawg thiab ua kom ib ce muaj zog. Lawv xum noj tshuaj tuag. Tseem ceeb tshaj plaws nws ntseeg tias lwm txoj kev kho tau zoo, tsuas yog siv tshuaj thiab txhaj tshuaj loj ntawm cov tshuaj insulin, tsis muaj nyob. Yog li, cov kws kho mob tseem siv cov tshuaj muaj suab thaj uas tsis ua rau txo kev tuag. Txog Ntshav Qab Zib-Med.Com koj tuaj yeem pom nws yooj yim npaum li cas los tswj hom mob ntshav qab zib hom 2 yam tsis muaj kev tshaib plab thiab kev noj tshuaj insulin. Tsis tas yuav siv cov tshuaj phom sij, vim lwm txoj kev kho tau pab zoo.

Kev kho mob ntshav siab nyob rau hauv cov neeg mob uas muaj hom 1 thiab ntshav qab zib hom 2
Siab ntsiav tshuaj Noliprel - Perindopril + Indapamide

Hloov kho cov ntsiav tshuaj

Diabeton MV - hloov cov ntsiav tshuaj tso tawm. Cov tshuaj nquag - gliclazide - raug tso tawm los ntawm lawv maj mam, thiab tsis sai. Vim tias qhov no, ib qho kev sib xyaw xim ntawm gliclazide hauv cov ntshav tau khaws cia 24 teev. Noj cov tshuaj no ib hnub ib zaug. Raws li txoj cai, nws yog tsim tawm thaum sawv ntxov. Cov Ntshav Qab Zib Muaj Feem (yam tsis muaj CF) yog hom tshuaj qub. Nws cov ntsiav tshuaj yaj tag rau hauv lub plab zom mov tom qab 2-3 teev. Txhua tus gliclazide uas nws muaj tam sim ntawd nkag rau hauv cov ntshav ntshav. Diabeton MV qis qis dua cov piam thaj kom huv si, thiab cov ntsiav tshuaj ib txwm muaj, thiab lawv cov nyhuv sai sai.

Cov ntsiav tshuaj tso tawm niaj hnub no muaj qhov zoo tseem ceeb dua cov tshuaj laus dua. Lub ntsiab yog tias lawv muaj kev nyab xeeb dua. Tus mob ntshav qab zib MV ua rau lub ntsej muag ntshav qab zib (qis qab zib) ntau zaus tsawg dua li niaj zaus Diabeton thiab lwm yam sulfonylurea derivatives. Raws li kev tshawb fawb, qhov kev pheej hmoo ntawm lub qog ntshav qab zib tsis ntau tshaj 7%, thiab feem ntau nws ploj mus yam tsis muaj tsos mob. Tawm tsam cov keeb kwm yav dhau los ntawm kev noj tshuaj tshiab, mob ntshav qab zib tsawg kawg nrog kev hnov mob tsis tshua muaj tshwm sim. Cov tshuaj no tau pom zoo zoo. Cov kev mob tshwm sim muaj qhia tsis ntau tshaj 1% ntawm cov neeg mob.

Kev sib piv ntawm Cov Mob Ntshav Qab Zib MV thiab Cov Kev Tso Tawm Ceev

Hloov kho cov ntsiav tshuaj	Cov ntsiav tshuaj ceev ceev
Pes tsawg zaus ib hnub twg noj	Ib hnub	1-2 zaug ib hnub
Kev mob ntshav siab	Tus nqi tsawg	Siab
Ua rau lub cell txo kev txiav tawm	Qeeb	Ceev ceev
Tus neeg mob lub cev hnyav ntxiv	Tsis Tseem Ceeb	Siab

Hauv cov ntawv xov xwm hauv cov ntawv kho mob, lawv nco ntsoov tias cov roj ntsha ntawm cov ntshav qab zib MV yog cov tshuaj tua kab mob vim nws cov qauv tshwj xeeb. Tab sis qhov no tsis muaj qhov nqis tiag, nws tsis cuam tshuam rau qhov txiaj ntsig ntawm kev kho mob ntshav qab zib. Nws paub zoo tias Diabeton MV txo qis qhov tsim los ntawm cov ntshav txhaws hauv cov ntshav. Qhov no tuaj yeem txo qhov kev pheej hmoo ntawm mob stroke. Tab sis tam sim no tsis tau muaj pov thawj tias cov tshuaj tiag tiag muab cov nyhuv zoo li ntawd. Qhov tsis zoo ntawm cov tshuaj ntshav qab zib, sulfonylurea derivatives, tau teev saum toj no. Hauv Diabeton MV, qhov tsis zoo no yuav tsis tshua hais tshaj hauv cov tshuaj qub. Nws muaj cov txiaj ntsig zoo dua ntxiv ntawm cov beta hlwb ntawm cov txiav. Hom insulin ntshav qab zib tsis loj hlob sai.

Yuav noj cov tshuaj no li cas

Mob ntshav qab zib MV noj ib hnub ib zaug, feem ntau yog noj tshais. Ib lub 60 mg notched ntsiav tshuaj tuaj yeem faib ua ob ntu kom tau txais koob tshuaj 30 mg. Txawm li cas los xij, nws tsis tuaj yeem zom lossis zuaj. Siv tshuaj nrog dej. Cov ntshav qab zib-Med.Com lub vev xaib txhawb txoj kev kho mob zoo rau hom ntshav qab zib hom 2. Lawv tso cai rau koj kom koj tso tseg cov neeg mob ntshav qab zib, kom tsis txhob muaj qhov cuam tshuam rau nws cov teebmeem. Txawm li cas los xij, yog tias koj noj tshuaj noj, ua txhua hnub yam tsis muaj khoob. Txwv tsis pub qab zib yuav nce siab dhau.

Nrog rau kev noj ntshav qab zib, kev haus cawv ntau tuaj yeem yuav muaj kab mob ntau ntxiv. Cov tsos mob tshwm sim yog mob taub hau, ua tsis taus pa, pws tsaug zog, mob plab, xeev siab thiab ntuav.

Mob ntshav qab zib tuaj yeem ua rau cov ntshav qab zib tsawg, thiab cawv yuav npog nws cov tsos mob. Qhov no yog qhov txaus ntshai! Tsaus muag vim tsis muaj suab thaj zoo li cov cawv ua rau qaug cawv. Muaj kev pheej hmoo siab tuag! Txo koj txoj kev nqus ntawm tus ntsuj plig los yog tsis txhob haus cawv. Tsawg kawg, xyuas seb yuav ua li cas haus dej haus cawv kom nyab xeeb.

Cov tsim tawm ntawm sulfonylureas, suav nrog Diabeton MV, tsis yog thawj txoj kev xaiv tshuaj rau ntshav qab zib hom 2. Raws li kev lees paub, nws raug pom zoo tias cov neeg mob yuav tsum tau kho ua ntej ntawm txhua daim metformin ntsiav tshuaj (Siofor, Glucofage). Maj mam, lawv cov koob tshuaj tau nce ntxiv rau qhov siab kawg ntawm 2000-3000 mg ib hnub twg. Thiab tsuas yog tias qhov no tsis txaus, ntxiv ntau Diabeton MV. Cov kws kho mob muab tshuaj kho ntshav qab zib kom tsis txhob siv cov tshuaj metformin ua txhaum. Ob qho tshuaj yuav tuaj yeem ua ke, thiab qhov no muab cov txiaj ntsig zoo. Zoo dua, hloov mus rau hom 2 kho mob ntshav qab zib pab cuam los ntawm tsis lees noj tshuaj tsis zoo.

Cov tsim tawm ntawm sulfonylureas ua rau cov tawv nqaij raug yoog mus rau ultraviolet hluav taws xob. Kev pheej hmoo ntawm tshav kub nce ntxiv. Nws raug nquahu kom siv cov tshuaj pleev thaiv hnub, thiab nws zoo dua tsis txhob pleev rau hnub. Xav txog qhov kev pheej hmoo ntawm hypoglycemia uas Diabeton yuav ua rau. Thaum tsav tsheb los yog ua haujlwm muaj kev phom sij, sim koj qab zib nrog glucometer txhua txhua 30-60 feeb.

Leej twg tsis haum rau nws

Tus mob ntshav qab zib MB yuav tsum tsis txhob noj rau txhua tus, vim tias lwm txoj kev kho mob ntshav qab zib hom 2 pab tau zoo thiab tsis ua rau muaj kev phiv tshuaj. Cov nom tswv contraindications muaj nyob hauv qab no. Kuj tseem pom tias pawg twg ntawm cov neeg mob yuav tsum tau muab cov tshuaj no nrog ceev faj.

Thaum cev xeeb tub thiab pub niam mis, ib qho ntsiav tshuaj txo qis qab zib yog contraindicated. Mob ntshav qab zib MV tsis tau sau tseg rau cov menyuam yaus thiab cov hluas, vim tias nws cov hauj lwm zoo thiab kev nyab xeeb rau pawg neeg mob no tseem tsis tau tsim. Tsis txhob noj cov tshuaj no yog tias yav dhau los koj tau ua xua rau nws lossis nrog lwm tus sulfonylurea derivatives. Cov tshuaj no yuav tsum tsis txhob noj los ntawm cov neeg mob uas muaj ntshav qab zib hom 1, thiab yog tias koj muaj qhov tsis ruaj khov ntawm hom 2 mob ntshav qab zib, nquag tshwm sim ntawm ntshav qog ntshav qab zib.

Yog tias koj ua raws li cov zaub mov tsis muaj carbohydrate, muaj kev pheej hmoo siab tias Diabeton ntsiav tshuaj yuav ua rau muaj ntshav qab zib tsawg. Nws yog ib qho tsim nyog los txo cov ntau npaum, tab sis nws yog qhov zoo dua rau kev tso tseg lawv cov kev nkag mus suav daws. Lwm txoj kev kho rau cov mob ntshav qab zib hom 2 raws li kev noj haus cov zaub mov uas tsis muaj carbohydrate tsawg cov piam thaj kom zoo, yog li tsis tas yuav siv cov tshuaj phem.

Sulfonylurea derivatives tsis tuaj yeem siv rau cov neeg mob siab thiab mob raum. Yog tias koj muaj ntshav qab zib nephropathy - sab laj nrog koj tus kws kho mob. Feem ntau yuav luag, nws yuav qhia hloov cov ntsiav tshuaj nrog kev siv tshuaj insulin. Rau cov neeg laus dua, Diabeton MV tau raug cai yog tias lawv lub siab thiab lub raum ua haujlwm zoo. Tsis raws kev raws cai, nws ua rau kev hloov pauv ntawm cov ntshav qab zib hom 2 mus rau hom kab mob ntshav qab zib insulin ntau. Yog li, cov neeg mob ntshav qab zib uas xav ua lub neej ntev yam tsis muaj teeb meem zoo dua yog tias tsis noj tshuaj.

Nyob rau qhov xwm txheej twg yog Diabeton MV tau ceeb toom nrog:

hypothyroidism - txoj haujlwm tsis muaj zog ntawm cov thyroid caj pas thiab qhov tsis txaus rau nws cov tshuaj hormones hauv cov ntshav,
tsis muaj peev xwm ua rau cov tshuaj hormones tsim los ntawm cov qog adrenal thiab cov qog pituitary,
kev noj zaub mov tsis xwm yeem
quav cawv.

Diabeton analogues

Tus thawj cov tshuaj Diabeton MV yog tsim los ntawm lub chaw muag tshuaj Lub Chaw Siv Tshuaj (Servier) (Fab Kis). Txij li thaum Lub Kaum Hlis 2005, nws tau tsum tsis muab cov tshuaj ntawm cov tub ntxhais hluas dhau los rau Russia - Diabeton 80 mg sai ntsiav tshuaj. Tam sim no koj tuaj yeem yuav xwb thawj Diabeton MV - hloov kho ntsiav tshuaj. Daim ntawv muab cov tshuaj no muaj qhov zoo, thiab cov khw tau txiav txim siab mloog zoo. Txawm li cas los xij, gliclazide hauv cov ntsiav tshuaj tawm sai yog tseem muag. Cov no yog cov analogues ntawm Diabeton, uas yog tsim los ntawm lwm cov tuam ntxhab.

Cov tshuaj ntawm cov tshuaj Ntshav qab zib MV

Lub npe tshuaj	Tuam txhab tsim khoom lag luam	Ncig Teb Chaws
Glidiab MV	Akrikhin	Lavxias
Lawbalong	Synthesis OJSC	Lavxias
Gliclazide MV	LLC Ozone	Lavxias
Diabefarm MV	Kws Tshuaj Ntau Lawm	Lavxias

Cov tshuaj ntawm cov ntsiav tshuaj Ntshav qab zib ntawm kev tso tawm sai

Lub npe tshuaj	Tuam txhab tsim khoom lag luam	Ncig Teb Chaws
Glidiab	Akrikhin	Lavxias
Glyclazide-AKOS	Synthesis OJSC	Lavxias
Diabinax	Shreya lub neej	Is Nrias teb
Diabefarm	Kws Tshuaj Ntau Lawm	Lavxias

Kev npaj uas nws nquag muaj tshuaj gliclazide hauv cov ntsiav tshuaj tso tawm sai yog tam sim no tsis siv lawm. Nws raug nquahu kom siv Diabeton MV lossis nws cov analogues hloov. Txawm tias zoo dua yog kev kho mob rau tus mob ntshav qab zib hom 2 raws li kev noj haus cov zaub mov uas muaj cov rog carbohydrate tsawg. Koj yuav muaj peev xwm ua kom cov ntshav qab zib nyob ruaj khov, thiab koj tsis tas yuav siv cov tshuaj phom sij.

Diabeton lossis Maninil - uas zoo dua

Lub hauv paus rau ntu no yog cov ntawv sau "Kev pheej hmoo ntawm kev dav dav thiab lub plawv kev tuag, nrog rau cov kab mob myocardial infarction thiab mob ntshav qab zib hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus nyob ntawm seb hom pib kho hypoglycemic" hauv phau ntawv journal "Ntshav Qab Zib" No. 4/2009. Tus sau ntawv - I.V. Misnikova, A.V. Dreval, Yu.A. Kovaleva.

Txoj kev sib txawv ntawm kev kho mob ntshav qab zib hom 2 muaj qhov sib txawv ntawm kev pheej hmoo ntawm lub plawv, mob hlab ntsha tawg thiab tuag tag nrho hauv cov neeg mob. Cov kws sau ntawv ntawm tsab xov xwm tau txheeb xyuas cov ntaub ntawv muaj nyob rau hauv cov ntawv sau npe ntawm cov ntshav qab zib mellitus ntawm thaj av Moscow, uas yog ib feem ntawm Lub Xeev kev sau npe ntawm cov ntshav qab zib mellitus ntawm Lavxias Federation. Lawv tau tshawb xyuas cov ntaub ntawv rau cov tib neeg uas tau txheeb pom tias mob ntshav qab zib hom 2 nyob rau xyoo 2004. Lawv tau sib piv cov txiaj ntsig ntawm sulfonylureas thiab metformin yog tias tau kho rau 5 xyoos.

Nws muab tawm tias cov tshuaj - sulfonylurea derivatives - muaj kev phom sij ntau dua li pab tau. Lawv ua li cas piv nrog metformin:

txoj kev pheej hmoo ntawm kev dav dav thiab lub plawv kev tuag tau ob npaug,
Kev pheej hmoo mob plawv - nce 4.6 npaug,
txoj kev pheej hmoo ntawm mob hlab ntsha tawg tau nce peb zaug.

Tib lub sijhawm, glibenclamide (Maninil) tseem muaj kev phom sij ntau dua li gliclazide (Mob ntshav qab zib). Muaj tseeb, tsab xov xwm tsis tau qhia tias cov ntawv sau ntawm Manilil thiab Diabeton tau siv - txhawb kev tso tawm los sis cov tshuaj uas pom zoo. Nws yuav txaus siab los sib piv cov ntaub ntawv nrog cov neeg mob ntshav qab zib hom 2 uas tam sim ntawv kho cov tshuaj insulin tam sim ntawd tsis siv tshuaj. Txawm li cas los xij, qhov no tsis tau ua tiav, vim tias cov neeg mob zoo li ntawd tsis txaus. Feem coob ntawm cov neeg mob categorically tsis kam txhaj tshuaj insulin, yog li lawv tau muab tshuaj rau noj.

Cov Lus Nquag Nug thiab Cov Lus Teb

Tus kab mob ntshav qab zib tswj kuv cov ntshav qab zib hom 2 tau zoo rau 6 xyoo, thiab tam sim no tau tso tseg kev pab lawm. Nws nce nws koob tshuaj rau 120 mg ib hnub, tab sis cov piam thaj hauv ntshav tseem siab, 10-12 mmol / l. Vim li cas tshuaj ho ploj nws qhov kev ua tau zoo? Yuav kho tau li cas tam sim no?

Diabetone yog sulfonylurea derivative. Cov tshuaj no txo cov ntshav qab zib, tab sis kuj muaj cov nyhuv tsis zoo. Lawv maj mam ua kom puas rau pancreatic beta hlwb. Tom qab 2-9 xyoo ntawm lawv cov kev nkag rau hauv tus neeg mob, insulin tsis txaus nyob rau hauv lub cev. Cov tshuaj tau poob nws qhov kev ua tau zoo vim tias koj lub npov beta tau "hlawv tawm." Qhov no yuav muaj tshwm sim ua ntej. Yuav kho tau li cas tam sim no? Yuav tsum tau txhaj cov tshuaj insulin, tsis muaj kev xaiv. Vim tias koj muaj ntshav qab zib hom 2 hloov mus ua hom mob ntshav qab zib hom 1. Ncua tseg Diabeton, hloov mus rau kev noj zaub mov kom tsis rog lossis haus kom tsawg thiab txhaj tshuaj ntxiv kom muaj ntshav qab zib kom qis.

Cov neeg laus tau mob ntshav qab zib hom 2 tau 8 xyoo. Cov ntshav qab zib 15-17 mmol / l, cov kev tsim mob hnyav tshwm sim. Nws coj manin, tam sim no pauv mus rau Diabeteson - tsis muaj dab tsi. Kuv puas yuav tsum pib noj cov tshuaj amaryl?

Qhov xwm txheej zoo li tus sau ntawm cov lus nug dhau los. Vim ntau xyoo ntawm kev kho tsis raug, hom 2 mob ntshav qab zib tau hloov pauv mus rau hom mob ntshav qab zib hom 1 ntau. Tsis muaj tshuaj yuav muab qhov tshwm sim. Ua raws li hom kabmob ntshav qab zib hom 1, pib txhaj insulin. Hauv kev xyaum, feem ntau nws tsis tuaj yeem tsim kho txoj cai kho rau cov neeg mob ntshav qab zib. Yog hais tias tus neeg mob qhia tsis nco qab thiab mob siab - tawm txhua yam raws li nws, thiab tos twj ywm.

Txog hom mob ntshav qab zib hom 2, tus kws kho mob tau sau 850 mg rau ib hnub Siofor rau kuv. Tom qab 1.5 lub hlis, nws pauv mus rau Diabeton, vim tias qab zib tsis poob txhua. Tab sis cov tshuaj tshiab no tseem siv me ntsis. Puas tsim nyog nws mus rau Glibomet?

Yog tias Diabeton tsis txo cov piam thaj, ces Glybomet yuav tsis muaj kev siv lawm. Xav kom qis dua cov piam thaj - pib txhaj cov tshuaj insulin. Txog rau qhov xwm txheej ntawm tus kab mob ntshav qab zib siab, tsis muaj lwm yam tshuaj zoo tau tseem tau tsim. Ua ntej tshaj plaws, hloov mus rau qhov kev noj haus kom tsawg cov zaub mov kom tsawg thiab tsis txhob noj cov tshuaj phem. Txawm li cas los xij, yog tias koj twb muaj keeb kwm ntev ntev ntawm tus mob ntshav qab zib hom 2 thiab koj tau raug kho tsis raug nyob rau xyoo dhau los, ces koj kuj yuav tsum tau txhaj tshuaj insulin. Vim tias tus txiav ua kom tiav thiab tsis tuaj yeem tiv tau yam tsis muaj kev txhawb nqa. Kev noj zaub mov kom tsawg-carbohydrate yuav txo koj cov piam thaj, tab sis tsis yog rau txoj cai. Yog li qhov kev tsis sib haum xeeb tsis tsim tawm, qab zib yuav tsum tsis siab tshaj 5.5-6.0 mmol / l 1-2 teev tom qab noj mov thiab sawv ntxov ntawm lub plab khoob. Maj mam txhaj cov tshuaj insulin me ntsis kom ua tiav lub hom phiaj no. Glibomet yog cov tshuaj sib xyaw. Nws suav nrog glibenclamide, uas muaj tib cov teeb meem cuam tshuam zoo li Diabeton. Tsis txhob siv cov tshuaj no. Koj tuaj yeem nqa tshuaj "ntshiab" metformin - Siofor lossis Glyukofazh. Tab sis tsis muaj tshuaj muaj peev xwm hloov cov tshuaj insulin.

Puas muaj peev xwm nrog tus mob ntshav qab zib hom 2 noj ntshav qab zib thiab reduxin rau cov kev poob phaus tib lub sijhawm?

Yuav ua li cas Diabeton thiab reduxin cuam tshuam nrog ib leeg - tsis muaj ntaub ntawv. Txawm li cas los xij, Diabeton stimulates zus ntawm insulin los ntawm tus txiav. Cov Insulin, nyeg, hloov cov piam thaj rau hauv cov rog thiab inhibits qhov tawg ntawm adipose ntaub so ntswg. Ntau cov insulin hauv cov ntshav, qhov nyuaj dua nws yog qhov poob phaus. Yog li, Diabeton thiab reduxin muaj qhov sib txawv. Reduxin ua rau muaj kev phiv loj heev thiab cov kev quav sai tshwm sim rau nws. Nyeem kab lus “Yuav ua li cas thiaj poob ceeb thawj nrog ntshav qab zib hom 2.” Tsis txhob noj ntshav qab zib thiab reduxin. Hloov mus rau qhov kev noj zaub mov tsis muaj roj kom tsawg. Nws normalizes qab zib, ntshav siab, roj cholesterol nyob rau hauv cov ntshav, thiab cov phaus ntxiv yuav ploj mus.

Kuv tau noj tshuaj Mob Ntshav Qab Zib MV tau 2 xyoo lawm, yoo cov piam thaj ceev txog 5.5-6.0 mmol / l. Txawm li cas los xij, qhov kev hnov mob nyob hauv kev txhais taw tau tsis ntev los no