Symlo 5 mg ntsiav tshuaj: cov lus qhia thiab tshuaj xyuas ntawm cov tshuaj

Muaj pes tsawg leeg Simlo

• SIMLO Coated ntsiav tshuaj

Cov kev zam: pob kws hmoov txhuv, lactose, microcrystalline cellulose, sodium starch glycolate, gelatinized hmoov txhuv, daj hlau oxide, isopropanol, hydroxytoluene butylate, dej lim, citric acid monohydrate, talc lim huv, magnesium stearate, hydroxyphenyl methylene dichlorophenylmethylene methyl.

10 Pcs. - hlwv (2) - pob khoom los ntawm cardboard.
10 Pcs. - hlwv (3) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (2) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (3) - pob khoom los ntawm cardboard.

Cov kev zam: pob kws hmoov txhuv, lactose, microcrystalline cellulose, sodium starch glycolate, gelatinized hmoov txhuv, liab hlau oxide, isopropanol, hydroxytoluene butylate, dej lim, citric acid monohydrate, talc purified, magnesium stearate, hydroxyphenylmethylene methylpropylene, methylene dichlorop.

10 Pcs. - hlwv (2) - pob khoom los ntawm cardboard.
10 Pcs. - hlwv (3) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (2) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (3) - pob khoom los ntawm cardboard.

Cov kev zam: pob kws hmoov txhuv, lactose, microcrystalline cellulose, sodium starch glycolate, gelatinized hmoov txhuv, liab hlau oxide, isopropanol, hydroxytoluene butylate, dej lim, citric acid monohydrate, talc purified, magnesium stearate, hydroxyphenylmethylene methylpropylene, methylene dichlorop.

10 Pcs. - hlwv (2) - pob khoom los ntawm cardboard.
10 Pcs. - hlwv (3) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (2) - pob khoom los ntawm cardboard.
14 pcs. - hlwv (3) - pob khoom los ntawm cardboard.

• SIMLO Coated ntsiav tshuaj

tab. sheath, 5 mg: 20, 28, 30 lossis 42 pcs.

• SIMLO Coated ntsiav tshuaj

tab. sheath, 10 mg: 20, 28, 30 lossis 42 pcs.

• SIMLO Coated ntsiav tshuaj

tab. sheath, 20 mg: 20, 28, 30 lossis 42 pcs.

Cov Lus Pom Txog Simlo

• SIMLO Coated ntsiav tshuaj

- mob siab mob siab,

- mob siab daim siab mob nyob rau theem mob,

- ib qho kev pheej tsis tu ncua ntxiv hauv cov haujlwm ntawm transaminases ntawm cov tsis paub keeb kwm,

- lactation (pub niam mis),

- menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 17 xyoo,

- Cov tshuaj tiv thaiv tsis haum rau simvastatin thiab lwm yam tshuaj,

- Kev ua haujlwm tsis haum rau lwm qhov HMG-CoA reductase inhibitors.

Muab koob tshuaj thiab cov thawj coj Simlo

• SIMLO Coated ntsiav tshuaj

Qhov ntau npaum cas thiab qhov ntev ntawm kev kho mob tau teeb tsa ua ib tus zuj zus.

Ua raws li qhov mob hnyav ntawm hypercholesterolemia, thawj koob tshuaj yog 5 mg / hnub. Nrog rau qhov mob siab hypercholesterolemia - 10 mg 1 lub sijhawm / hnub. Yog tias tsim nyog, nce qhov koob tshuaj nrog ib ncua sijhawm 4 lub lis piam. Qhov nyiaj pab ntau tshaj txhua hnub yog 40 mg.

Cov tshuaj yuav tsum noj 1 zaug / hnub nyob rau yav tsaus ntuj, ua ntej lossis thaum noj mov.

Rau cov neeg mob uas tau txais cov tshuaj txhaj tiv thaiv kab mob, qhov xav kom pib siv yog 5 mg / hnub, qhov siab tshaj plaws txhua hnub yog 5 mg / hnub.

Cov neeg mob uas mob me me los yog mob raum tsis txaus noj tsis tas yuav tau kho cov tshuaj ntau npaum li cas. Rau cov neeg mob uas mob raum tsis zoo, thawj zaug tshuaj yog 5 mg / hnub, thaum pawg neeg mob no yuav tsum tau tshuaj xyuas mob tas li.

Sab Sab Simlo

• SIMLO Coated ntsiav tshuaj

Los ntawm cov txheej txheem hauv plab zom mov: feem ntau - cem quav, raws plab, tsis qab los noj mov, pom zoo, xeev siab, mob plab, txhaws qa, tej zaum muaj kev nce ntxiv hauv theem ntawm transaminases thiab CPK hauv cov ntshav plasma (feem ntau nyob rau thaum xaus ntawm thawj lub hlis ntawm kev kho). Lub sijhawm nruab nrab ntawm lub asthiv thib 2 thiab 4 txij li pib kev kho mob, kev nce ntshav ntau ntxiv ntawm ALT, AST thiab alkaline phosphatase yog ua tau. Qhov siab tshaj plaws nce hauv cov ntsuas no tau pom nyob ib ncig ntawm 8 lub lim tiam ntawm kev kho mob. Tom qab tsis ua hauj lwm ntawm kev kho tshuaj, ntau qib enzyme yog txo kom tsawg.

Ntawm ib feem ntawm cov hlab plawv: kev mob ntshav khov yog qhov ua tau (feem ntau tshwm sim thaum noj cov tshuaj ntawm 10 mg / hnub, yog qhov hloov mus rau qhov xwm txheej thiab tsis tas yuav tsum tau kho ntawm ntau npaum li cas).

Los ntawm lub hauv nruab nrab hauv lub paj hlwb thiab lub paj hlwb peripheral: mob taub hau, pw ntxhov, asthenia, kiv taub hau yog ua tau.

Los ntawm cov leeg musculoskeletal: tsis tshua muaj - myopathy, rhabdomyolysis.

Los ntawm cov kab mob hemopoietic: tsis tshua muaj - eosinophilia, thrombocytopenia.

Kev ua xua: tsis tshua muaj - urticaria, angioedema.

Lwm yam: tsis tshua muaj tshwm sim - photosensitization, vasculitis, lupus-zoo li syndrome.

Cov tshuaj feem ntau zoo tiv thaiv. Cov kev mob tshwm sim feem ntau yog me me thiab hloov dua tshiab.

• SIMLO Coated ntsiav tshuaj

Cov ntaub ntawv ntawm kev tshaj tawm ntawm cov tshuaj Simlo tsis muab.

• SIMLO Coated ntsiav tshuaj

Nrog tib lub sijhawm siv Simlo nrog cov tshuaj tiv thaiv kab mob (cyclosporine), erythromycin, gemfibrozil, nicotinic acid, qhov kev pheej hmoo ntawm rhabdomyolysis thiab mob raum tsis zoo nce.

Nrog rau kev siv tib lub Simlo nrog cov tshuaj tiv thaiv tsis tau, kev nce qib hauv kev txiav txim ntawm qhov kawg tau ua tau.

Nrog rau kev siv Simlo ib txhij nrog colestyramine, qhov kev nyab xeeb ntawm simvastatin poob qis (nws raug nquahu kom Simlo 4 teev tom qab noj colestyramine).

Nrog rau kev siv tib lub Simlo nrog digoxin, kev nce ntxiv ntawm qhov kawg ntawm cov ntshav hauv ntshav tshwm sim.

• SIMLO Coated ntsiav tshuaj

Nrog kev ceev faj, cov tshuaj yuav tsum tau tsim rau cov neeg mob uas quav cawv thiab / lossis muaj keeb kwm muaj kab mob siab.

Nrog kev ceev faj, cov tshuaj yuav tsum raug kho rau cov neeg mob tom qab hloov khoom nruab nrog cev tau txais tshuaj tiv thaiv kab mob, vim tias qhov pheej hmoo ntawm rhabdomyolysis thiab kev txhim kho lub raum tsis ua haujlwm.

Nrog kev mob ntshav hauv lub plawv, mob sib kis ceev, nrog cov teeb meem loj hauv lub cev, endocrine system, dej-electrolyte tshuav, thaum muaj kev cuam tshuam kev phais mob (suav nrog kev kho hniav) lossis raug mob, hauv cov neeg mob txo lossis nce ntxiv ntawm pob txha pob txha ntawm cov leeg tsis paub, nrog qaug dab peg, cov tshuaj tau tawm nrog ceev faj, vim hais tias cov kab mob thiab kab mob tuaj yeem ua rau mob raum tsis zoo.

Kuaj xyuas

Thaum lub sijhawm siv cov tshuaj, nws yog ib qho tsim nyog los tswj cov plasma cholesterol cov ntsiab lus. Thawj qhov kev tshawb fawb tau nqa tawm 4 lub lis piam tom qab pib siv tshuaj, tom qab ntawd kev soj ntsuam cov kab mob tsis tu ncua ntawm qhov ntsuas no tau ua.

Ua ntej thiab thaum kho nrog cov tshuaj, cov ntsiab lus ntawm daim siab enzymes hauv cov ntshav yuav tsum tau saib xyuas: thaum thawj 3 lub hlis ntawm kev kho, kev saib xyuas yog nqa nrog lub sijhawm ntawm 6 lub lis piam, tom qab ntawd txhua 6 lub hlis. Nrog kev nce qib hauv cov ntshav transaminase ntau dua los ntawm ntau tshaj 3 zaug piv nrog theem pib, kev kho mob nrog Simlo yuav tsum tau txiav.

Thaum lub sijhawm siv cov tshuaj, nws yog ib qho tsim nyog los tswj qib ntawm CPK hauv cov neeg mob uas tau txais ob qho tshuaj tiv thaiv kab mob los yog nicotinic acid, thiab nrog myopathy (myalgia, leeg tsis muaj zog). Nrog rau kev nce qib hauv qib ntawm CPK los ntawm ntau dua 10 zaug piv nrog cov txiaj ntsig zoo li qub, cov tshuaj yuav tsum tau txiav.

• SIMLO Coated ntsiav tshuaj

Cov tshuaj yuav tsum tau muab cia rau hauv qhov chaw qhuav, tiv thaiv los ntawm lub teeb, tawm ntawm cov menyuam yaus ntawm qhov kub tsis tshaj 25 ° C.

Txee lub neej yog 2 xyoos. Cov tshuaj yuav tsum tsis txhob siv tom qab hnub tas sij hawm qhia ntawm pob.

Cov tshuaj muaj pes tsawg leeg

Txhua lub ntsiav tshuaj Simlo yog coated nrog ib tus neeg zaj duab xis txheej, thiab muaj cov hauv qab no:

Cov khoom xyaw dhia: simvastatin 10,000 mg

• Lactose monohydrate nyob rau hauv ib qhov nyiaj ntawm 75,500 mg,
• Citric acid monohydrate tsis ntau tshaj li 1,250 mg,
• Ascorbic acid 2,500 mg,
• Cellulose hauv ib qhov loj ntawm 9,400 mg,
• Magnesium stearate 1,200 mg.

Lub plhaub muaj: hypromellose, tolk, titanium dioxide 0.520 mg, daj hlau oxide zas 0.002 mg, macrogol-400 0.120 mg., Cov hlau oxide liab oxide 0.038 mg.

Txhua Lub Simlo 20 mg ntsiav tshuaj nrog zaj duab xis txheej muaj:

Lub cev nquag ua haujlwm: tivthaiv simvastatin 20,000 mg.

• 151,000 mg lactose monohydrate,
• 2,500 mg hmoov nplej pregelatinized,
• Silicon dioxide colloidal 2,400 mg,
• Sodium carboxymethyl hmoov txhuv nplej siab (hom A) 15,000 mg,
• Butylhydroxytoluene 0.040 mg,
• Citric acid monohydrate 2,500 mg,
• Pob kws hmoov txhuv nplej siab hauv qhov ntau tshaj 20.360 mg,
• 5,000 mg ascorbic acid,
• Microcrystalline cellulose nyiaj muaj 18,800 mg,
• cov tshuaj ntawm magnesium stearate tsis ntau tshaj 2,400 mg.

Lub plhaub tshuaj muaj: talcum loj 1,040 mg, hypromellose hauv 2,400 mg, titanium dioxide hauv qhov loj ntawm 1,040 mg, hlau zas hlau oxide 0,036 mg, macrogol-400 0,240 mg, daj hlau oxide zas 0,044 mg.

Simlo qhia rau siv nyob rau qee qhov xwm txheej:

1. Nrog hyperlipidemia, nyob rau hauv rooj plaub thaum kev kho kev noj zaub mov noj nrog cov roj cholesterol tsawg thiab lwm yam kev ntsuas tsis muaj tshuaj tsis muaj txiaj ntsig.
2. Nyob rau hauv cov ntaub ntawv ntawm cov tsos ntawm kev pom ua ke nrog hypercholesterolemia, hypertriglyceridemia thiab hyperlipoproteinemia, uas tsis tuaj yeem kho los ntawm kev noj zaub mov tshwj xeeb lossis thauj khoom.
3. Thaum ib tug homozygous mob hom ntawv ntawm hypercholesterolemia tshwm sim.
4. Thaum kev mob plawv mob hnyav rau lub plawv (tshwm sim lwm yam kev tiv thaiv).
5. Thaum pom zoo siv rau cov neeg mob uas xav tau kom txo qis kev tuag.
6. Txo txoj kev pheej hmoo ntawm myocardial infarction.
7. Yog tias tsim nyog, txo txoj kev pheej hmoo ntawm lub cev tuag.

Cov lus sib xyaw thiab cov ntawv ntau npaum

Simlo yog daim ntawv tshuaj uas muaj cov nyhuv lipid-txo qis. Tus txheej txheem ntawm kev ua kom lub zog yog qhov ua kom tsis txhob muaj cov enzymatic ntawm HMG-CoA reductase.

Daim ntawv tso tawm Simlo - tsiav tshuaj thiab ntsiav tshuaj, zaj duab xis-txheej saum. Hauv peb lub khw muag tshuaj muaj peb ntau kev hloov ntau - 5, 10 thiab 20 mg.

Yam khoom muaj sia - simvastatin (simvastatin - raws li lub radar - siv tshuaj yaj yeeb). Cov tshuaj ntxiv uas ua rau lub ntsiav tshuaj: pob kws hmoov txhuv nplej siab, ferrum oxide, 4-valent titanium oxide, microcrystalline thiab hydroxypropylmethyl cellulose, isopropanol, methylene chloride, citric acid monohydrate.

Kev cuam tshuam ntawm cov tshuaj pharmacological ntawm kev siv cov simvastatin no cuam tshuam nrog nws lub peev xwm los tiv thaiv kev tsim cov roj hauv ntshav ua ntej los ntawm lub cev. Yog li, tom qab nws siv, muaj txo qis hauv feem ntawm cov rog hauv cov ntshav. Hauv tshwj xeeb, qhov concentration ntawm triglycerides, LDL thiab VLDL, cov roj (cholesterol) tag nrho tsawg, qhov sib piv ntawm lipoproteins rau txhua lwm qhov zoo dua, thiab qhov sib piv ntawm cov roj (cholesterol) tag nrho nrog nws cov feem (cov ntsiab lus ntawm cov roj (cholesterol) thiab HDL yog muaj kev tiv thaiv ib nrab).

Txoj kev kho kom zoo tshwm sim ob lub lis piam tom qab pib noj Simlo. Qhov siab ntawm cov nyhuv kho tshwm sim nyob rau lub sijhawm dhau los ntawm plaub mus txog rau lub lim tiam thib rau ntawm kev siv statin. Ntxiv mus, cov nyhuv no tseem nyob hauv txoj kev kho mob, txawm li cas los xij, thaum txoj kev kho mob tso tseg, daim duab lipid tshuav nyiaj yuav rov qab mus rau theem pib ua ntej kev kho tshuaj.

Pharmacokinetic cov yam ntxwv suav nrog kev nqus sai ntawm lub plab hnyuv thaum coj qhov ncauj. Biotransformation thiab cov metabolism ntawm simlo tshwm sim hauv lub siab. Lub cev siv tshuaj tiv thaiv kab mob tau tsim nyob rau ntawd, uas yog beta-hydroxymetabolites. Txog 95% ntawm lawv khi rau cov protein ua cov ntshav.

Txoj hauv kev tseem ceeb ntawm kev nthuav tawm ntawm cov khoom seem ntawm cov tshuaj yog nrog cov kua tsib thiab ob lub raum. Tias yog vim li cas, cov paib tsis yog tshuaj rau cov kab mob ntawm lub raum thiab mob siab nyob rau theem ntawm qhov mob tshwm sim. Thaum lub sijhawm siv cov tshuaj simvastatin, plasma transaminases thiab CPK yuav tsum tau saib xyuas tsis tu ncua.

Rau cov kab mob ntshav siab rau ntshav ntshav, thawj zaug kev kawm yuav tsum tau ua rau lub lis piam tom qab pib kev kho mob.

Sab sij huam

Muaj qee zaus, tus neeg mob lub cev muaj peev xwm muab ntau cov lus teb rau siv cov cim. Cov lus hauv qab no yog ntaus nqi rau qhov ua tau cov tsos mob:

1. Kev tsis txaus siab noj mov, muaj peev xwm nthuav dav ntawm ob qho raws plab thiab cem quav, uas yuav nrog ntu ntawm kev xeev siab, pom pob thiab mob plab.
2. Arterial hypotension yog ua tau - qhov mob uas ntshav siab poob qis dua cov lej ib txwm, cov teeb meem metabolic tsis txaus.
3. Cephalgia, mob nruab nrog leeg.
4. Kev mob leeg nqaij - xws li mob myopathy, mob hauv cov leeg nqaij, hauv cov xwm txheej hnyav - rhabdomyolysis los ntawm cov kab mob urinary nrog lub raum tsis zoo.
5. Cov tshuaj tiv thaiv lub cev tsis haum thiab lwm yam txheej txheem autoimmune - vasculitis, kev ua xua pob, ua kom mob ntsws mob ntsws.
6. Cov tawv nqaij ua pob, ua pob liab liab, khaus.
7. Hauv kev kawm tshawb fawb los ntawm cov kab mob hematopoietic, tsis tshua muaj qhov tsis tshua muaj kev coj ua nyob rau hauv cov kev coj ntawm cov duab anemia thiab eosinophilia.

Yog tias koj muaj ib lossis ntau ntawm cov tsos mob tau hais los saud, koj yuav tsum hu rau koj tus kws kho mob tam sim ntawd thiab, yog tias tsim nyog, txo qhov koob tshuaj, lossis tag nrho tsis siv nws.

Kev cuam tshuam nrog lwm yam tshuaj

Simlo yuav tsum tau ua ke nrog kom zoo nrog cov tshuaj xws li fibrates (gemfibrozil), cyclosporine, niacin, erythromycin, thiab tus lej ntawm lawv cov analogues. Thaum siv nyob rau hauv parallel nrog lawv, lub bioavailability ntawm cov tshuaj nce, lawv plasma concentration nce, qhov kev pheej hmoo ntawm rhabdomyolysis hloov zuj zus ob peb zaug, tom qab ntawd lub raum tsis ua haujlwm, thiab tshwj xeeb tshaj yog nrog kev mob ntshav hypotension.

Thaum ua ke nrog cov tshuaj tiv thaiv kev puas tsuaj, simvastatin tuaj yeem txhim kho lawv cov nyhuv. Kev saib xyuas tshwj xeeb yuav tsum tau them rau cov neeg mob plawv tsis ua hauj lwm uas tau txais kev kho mob nrog plawv glycosides - digoxin. Simvastatin ua rau nws cov tshuaj plasma ntau dua, uas, muab cov khoom ntawm glycoside, tuaj yeem muab cov kev mob hnyav rau cov hlab plawv, ua kom cov kab mob plawv txaus.

Cov Sim Ceeb Simlo

Hauv peb txoj kev lag luam kws tshuaj, Simlo statin muaj ntau ntawm cov qauv ua qauv. Cov no suav nrog kev hloov pauv rau cov tshuaj muaj txiaj ntsig - Simvakard 10, 20, 40 mg, Simgal 10, 20 thiab 40 mg, Vasilip 10, 20 thiab 40 mg.

Hloov maj mam hloov chaw. raws li lub ntsiab cai ntawm kev uaCov. Ntawm no, txoj kab ntawm cov tshuaj qub thiab cov generics yuav luag tsis muaj nyiaj - los ntawm Atorvastatin, Torvakard, Atoris, Liprimar, Krestor, rau Holetar, Lipostat, Livazo thiab Rosucard. Txhua tus ntawm lawv muaj lipid-txo cov teebmeem zoo thiab koom nrog pawg ntau ntawm cov tshuaj - statins.

Kev Siv Tshuaj Xyuas

Viktorova S.N., Moscow, kws kho mob ntawm cov qeb siab tshaj plaws, lub taub hau ntawm endocrinology chav haujlwm ntawm Lub Tsev Kho Mob Hauv Nroog No. 7: “Kuv tau raug teem Simlo rau kuv cov neeg mob tau ntau xyoo. Txaus siab nrog cov txiaj ntsig, cov tshuaj yeeb tshuaj stably qhia nws qhov ua tau zoo thiab kev muaj peev xwm ntawm cov tshuaj kho mob. Raws li rau statin, nws cov kev mob tshwm sim tsis tshua muaj neeg pom; kev kho mob los ntawm txhua tus neeg mob tau pom zoo zoo. Tom qab kev siv tshuaj kho mob, cov ntshav lipid ib txwm nyob ruaj khov. ”

Pavelko P.A. Kiev, 65 xyoo, nyiaj laus: "Txog plaub xyoos dhau los, tus kws kho mob tau hais kom Simlo rau kuv, vim tias muaj ntau yam kev hloov pauv los ntawm daim lipid profile. Raws li kuv tsis tuaj yeem hais meej, Kuv nco ntsoov tias muaj cov roj (cholesterol) thiab triglycerides ntau, yuav luag txhua qhov kev tsom xam yog txhawb zog. Tam sim no txhua hnub kuv noj tshuaj ntsiav thiab kev noj qab haus huv. Qhov kev ntxhov siab tsuas yog tias tam sim no tag nrho kuv lub neej kuv yuav tau zaum ntawm ntsiav tshuaj. Tus kws kho mob tau hais tias tom qab tsum tsis noj tshuaj ntxiv lawm, txhua tus po ntawm kuv cov hlab ntshav tuaj yeem rov qab los, yog li kuv yuav tsum tau noj tas li. "

Kev tshuaj xyuas txog Simlo los ntawm ob tus kws kho mob thiab tus neeg mob yog qhov zoo feem ntau ntawm cov neeg. Qhov no yog vim tus nqi zoo / zoo piv nrog ntev, thiab qhov tseem ceeb tshaj plaws, muaj kev vam meej hauv kev siv cov tshuaj no hauv cov tshuaj. Nws yog qhov tseeb pov thawj inhibitor ntawm HMG-CoA reductase, muaj ntau qhov sib txuam hauv cov khw muag tshuaj thiab tsis tshua muaj kev phiv tshuaj.

Cov lus qhia rau cov tshuaj no

Txhua pob ntawm cov tshuaj Simlo suav nrog cov lus qhia txog kev txais mus kawm.

Cov lus qhia rau cov tshuaj muaj cov ntaub ntawv hais txog qhov ntsuas, tsim nyog yuav tau noj tshuaj, kev phiv, contraindications, daim ntawv tso tawm, muaj pes tsawg leeg, ua rau kev noj tshuaj ntau dhau, txoj kev tswj hwm, kev txais neeg mob thaum cev xeeb tub lossis pub niam mis, chaw cia khoom, thiab txee lub neej.

Tsis tas li ntawd, tseem muaj cov ntaub ntawv ntawm tus nqi thiab kev hloov kho.

Kws Tshuaj

Cov tshuaj Simlo yog tsim los normalize cov roj feem ntawm cov ntshav. Lub hauv paus ntsiab lus ntawm cov nyhuv ntawm cov tshuaj Simlo yog ua raws li lub peev xwm ntawm nws lub hauv paus tseem ceeb los rhuav tshem cov txheej txheem sib tov ntawm ib qho ntawm cov cholesterol ua ntej nyob hauv daim siab.

Kev kho kom zoo ntawm cov tshuaj biochemical yog ib qho tseem ceeb tshaj plaws uas txo qis kev loj hlob ntawm cov mob atherosclerosis, uas txo txoj kev pheej hmoo ntawm kev tsim kab mob ischemic, thiab tseem yog kev tiv thaiv zoo heev ntawm cov tsos ntawm myocardial infarction.

Thaum noj, cov tshuaj pib tau adsorbed nyob rau hauv txoj hnyuv me. Nws yuav tsum raug sau tseg tias thawj theem pib ntawm fermentation ntawm cov tshuaj nquag tshwm sim hauv cov hnyuv phab ntsa. Thaum dhau los ntawm daim siab, feem ntau ntawm cov tshuaj raug hloov mus rau hauv ib qho kev tsim.

Kev ntsuas rau nkag

Cov tshuaj yog pom zoo rau kev siv:

1. Hyperlipidemia (tuaj yeem raug kho tsuas yog thaum tsis muaj txiaj ntsig kev noj zaub mov zoo thiab lwm yam kev ntsuas tsis siv tshuaj.
2. Coronary heart disease (nrog tiv thaiv theem ob).
3. Nrog rau kev sib xyaw ua ke ntawm kev kho mob hypercholesterolemia thiab hypertriglyceridemia.
4. Hyperlipoproteinemia, uas tuaj yeem kho tsis tau los ntawm kev noj zaub mov zoo, nrog rau kev ua lub cev.
5. Txo txoj kev pheej hmoo ntawm mob ntshav caj dab, nrog rau kev tiv thaiv ntawm myocardial infarction.
6. Kev cuam tshuam ncig ntawm lub hlwb.
7. Atherosclerosis

Kev Txais nyiaj

Saib xyuas! Yog tias yuav tsum tau, tus kws kho mob tuaj yeem hloov kho qhov ntau npaum.

Nrog hypercholesterolemia, kev muab tshuaj thawj zaug yuav tsum tsis pub ntau tshaj 5 mg / hnub. Nrog lub siab dhia hauv cov roj (cholesterol) hauv cov ntshav, ib cov tshuaj hauv cov tshuaj 10 mg.

Cov tshuaj yuav tsum muab rau tus neeg mob tsis pub ntau tshaj ib zaug ib hnub. Yog tias tsim nyog, nce ntxiv rau kev noj nrog lub sijhawm nrog plaub lub lis piam. Qhov siab tshaj plaws pub tau noj tshuaj uas yuav tau noj nyob rau ib hnub twg yog 40 mg. Lub cuab yeej tso cai rau coj mus thaum yav tsaus ntuj.

Hauv qhov no, cov tshuaj tuaj yeem ua kom qaug thaum noj mov lossis hauv pem hauv ntej. Rau cov neeg mob uas tau txais cov tshuaj tiv thaiv kab mob, cov tshuaj uas tau pom zoo yog tsib mg rau ib hnub.

Cov neeg mob uas muaj mob raum me me los sis hnyav, tsis tas yuav tau kho ntau npaum li cas.

Yog tias qhov lesion loj heev, ces kev siv tshuaj thawj zaug yuav tsum tsis pub ntau tshaj 5 mg rau ib hnub. Hauv qhov no, nws yog ib qho tseem ceeb uas yuav tsum tau mus kuaj mob tas li.

Nrog kev tso mob hauv lub siab me me, kev kho kom haum rau hauv lub siab kuj tsis tas yuav tsum ua. Yog tias swb yeej loj heev, Tom qab ntawd Simlo yuav tsum yauv tsum tsis noj cov tshuaj.

Txog kev kho mob ntawm IHD, ib hom tshuaj tawm hauv cov tshuaj 10 mg. Qhov ntau ntawm kev pub nkag mus ib hnub yuav tsum tsis muaj ntau tshaj ib zaug. Qhov ntau tau tso cai tshuaj yuav tsum yog 10 mg.

Kev sib xyaw ntawm cov nyiaj nrog lwm cov tshuaj

Nrog kev tswj hwm tib lub sijhawm ntawm Simplo nrog cyclosporine, gemfibrozil, erythromycin lossis nicotinic acid, qhov pheej hmoo ntawm rhabdomyolysis nce ntau zaug.

Thaum noj ua ke nrog cov tshuaj tiv thaiv tsis tau tiv thaiv, qhov tshwm sim ntawm tom kawg tuaj yeem nce ntxiv.

Thaum noj nrog roj cholesterol, lub bioavailability ntawm simvastatin txo qis. Yog tias noj ob yam tshuaj yog tsim nyog, ces Simlo yuav tsum tau noj 4 teev tom qab noj cholestyramine.

Cov tshuaj Simlo ob peb zaug ua rau nce siab ntawm digoxin hauv tib neeg cov ntshav.

Sab sij huam

Qee lub sij hawm lub cev cuam tshuam tuaj yeem teb, uas tuaj yeem tshwm nws tus kheej hauv tus neeg mob hauv daim ntawv ntawm cov tsos mob xws li:

1. Mob plab zom mov, cem quav, txo lossis ntau yam qab los noj mov, xeev siab, flatulence, pancreatitis, mob mob plab.
2. Kev Ntshav.
3. Mob hauv lub taub hau, peripheral neuropathy, paresthesia.
4. Myopathy, myalgia, rhabdomyolysis.
5. Lupus-zoo li tus mob ntsws, mob eosinophilia, ua tsis taus pa, vasculitis, angioedema, thrombocytopenia, ua npaws, mob caj dab, mob urticaria.
6. Cov tawv nqaij ua pob, ua xua ntawm daim tawv nqaij, khaus, alopecia, photosensitivity.
7. Mob Kev Plab

Yog tias cov tsos mob no pib tshwm sim, qhia rau tus kws kho mob tam sim ntawd.

Thaum cev xeeb tub

Cov tshuaj no yuav tsum tsis txhob noj thaum cev xeeb tub lossis pub niam mis, raws li Cov kev tsis ncaj ncees yuav pib tshwm sim hauv tus menyuam.

Cov tshuaj yuav tsum tau muab tso rau hauv qhov chaw uas qhov kub yuav tsis ntau tshaj 25 degrees.

Chav no yuav tsum sov so kom txaus, txias, thiab kuj tsaus ntuj nti. Cov tshuaj yuav tsum cia nyob deb ntawm menyuam yaus thiab tsiaj nyiam.

Raws li txhua qhov kev pom zoo, cov khoom lag luam tuaj yeem siv tau ob xyoos.

Ib cov tshuaj uas tau tso tawm tsis pub dhau sijhawm lawm, yog vim tias xws li lub cuab yeej yuav tsuas cuam tshuam koj lub cev twb cuam tshuam.

Nyob ntawm thaj av ntawd, tus nqi tuaj yeem sib txawv.

Hauv Lavxias tus nqi nyob ntawm 275 txog 390 rubles.

Nyob rau hauv Ukraine tus nqi raug muab kho thaum 198, 57 hryvnia.

Ntawm cov analogues ntawm cov cuab yeej no, nws muaj peev xwm kom paub qhov txawv ntawm cov tshuaj xws li Vazilip, Zovatin, Zokor, Levomir, Ovenkor, Simvakol, Simvastol, Simvagestal, Holvasim, Simplakor, Simvakard, Holvasim, Simvor, Sinkard, Simplakor, Simgal, zoo li lwm yam.

Thaum sau tshuaj rau ib qho tshuaj tiv thaiv kab mob, tus kws kho mob yuav tsum coj mus rau hauv lub peev nyiaj txiag ntawm tus neeg mob, nws qhov xwm txheej dav dav, thiab tseem muaj feem cuam tshuam rau cov khoom siv.

Ntawm qhov zoo, ib daim ntawv teev ntau ntawm cov qauv tuaj yeem sib txawv. Ib qho ntxiv, ntau tus kuj tseem paub qhov sib txawv ntawm cov qauv kev coj ua, nrog rau tus nqi pheej yig.

Los ntawm cons, cov neeg mob muaj xws li muaj cov contraindications thiab phiv.

Sab sij huam

Los ntawm lub plab zom mov: dyspepsia (xeev siab, ntuav, gastralgia, mob plab, cem quav lossis mob plab zawv plab, mob plab), mob siab, daj ntseg, nce kev ua haujlwm ntawm "mob siab" transaminases thiab alkaline phosphatase, CPK, tsis tshua muaj - mob pancreatitis.

Los ntawm cov leeg hlwb thiab cov khoom hauv lub cev: asthenia, kiv taub hau, mob taub hau, insomnia, ua kom huam, plab pheem, qhov tsis haum hlwb, qhov muag plooj, tsis pom kev, tsis hnov ​​qab.

Los ntawm cov leeg ua haujlwm: myopathy, myalgia, myasthenia gravis, tsis tshua muaj mob rhabdomyolysis.

Kev ua xua thiab tiv thaiv cov tshuaj tiv thaiv: mob caj dab, mob lupus-zoo li cov tsos mob, mob caj dab mob polymyalgia, mob rheumatism, mob vasculitis, thrombocytopenia, eosinophilia, nce ESR, mob caj dab, mob pob txaws, urticaria, photosensitivity, kub taub hau, hyperemia ntawm daim tawv nqaij, yaug ntsej muag.

Kev ua kom mob Dermatological: tawv nqaij ua pob, khaus, alopecia.

Lwm yam: ua kom ntshav txhaws, palpitations, mob raum tsis ua haujlwm (vim yog rhabdomyolysis), tsawg dua potency.

Cov lus qhia tshwj xeeb

Ua ntej pib txoj kev kho mob, nws yog ib qho tsim nyog yuav tau ua qhov kev kuaj mob siab ua haujlwm (saib xyuas cov haujlwm ntawm "daim siab" hloov tsheb txhua 6 lub lis piam rau thawj 3 lub hlis, tom qab ntawd txhua 8 lub lis piam rau cov seem thawj xyoo, thiab tom qab ntawd ib hlis ib zaug). Rau cov neeg mob tau txais simvastatin hauv ib hnub 80 mg, lub siab ua haujlwm tshuaj xyuas ib zaug txhua 3 lub hlis. Thaum muaj kev cuam tshuam ntawm kev ua haujlwm "mob siab" nce ntxiv (ntau dua 3 zaug ntawm qhov tsis suav qhov siab tshaj), kev kho mob raug tso tseg.

Hauv cov neeg mob nrog myalgia, myasthenia gravis thiab / lossis nrog kev nce siab hauv CPK cov haujlwm, kev kho tshuaj tsis pub muaj.

Simvastatin (ntxiv rau lwm qhov HMG-CoA reductase inhibitors) yuav tsum tsis txhob siv nrog kev pheej hmoo ntawm rhabdomyolysis thiab mob raum (vim muaj mob hnyav, mob ntshav qis, kev phais loj, mob plig, thiab mob ntshav qab zib tsis txaus).

Kev tshem tawm cov kev kho mob lipid-txo qis thaum lub cev xeeb tub tsis cuam tshuam loj heev rau qhov tshwm sim ntawm kev kho mob mus ntev ntawm kev kho tus mob hypercholesterolemia.

Vim qhov tseeb tias HMG-CoA reductase inhibitors inhibit cholesterol synthesis, thiab cov roj cholesterol thiab lwm cov khoom ntawm nws cov synthesis ua lub luag haujlwm tseem ceeb hauv kev txhim kho cov menyuam hauv plab, suav nrog kev sib xyaw ntawm cov tshuaj steroids thiab cell cell, simvastatin tuaj yeem muaj qhov tsis zoo ntawm tus menyuam hauv lub cev thaum kws kho mob rau cov pojniam cev xeeb tub ( Cov poj niam ntawm kev muaj me nyuam hnub nyoog yuav tsum ua tib zoo ua raws li kev ntsuas kom tsis muaj menyuam). Yog tias cev xeeb tub tshwm sim thaum kho, cov tshuaj yuav tsum tsis ua ntxiv, thiab tus poj niam tau ceeb toom tias yuav muaj kev phom sij rau cov menyuam hauv plab.

Simvastatin tsis qhia nyob rau kis uas muaj hom I, IV, thiab V hypertriglyceridemia.

Nws ua tau zoo rau ob qho tib si hauv kev kho mob monotherapy, thiab ua ke nrog kev sib txuas ntawm cov kua tsib kua qaub.

Ua ntej thiab thaum kawg ntawm kev kho, tus neeg mob yuav tsum noj tshuaj kom tsis txhob mob hypocholesterol.

Yog tias tsis nco lub tshuaj tam sim no, cov tshuaj yuav tsum ua kom sai li sai tau. Yog tias nws yog lub sijhawm rau koob tshuaj ntxiv, tsis txhob txhaj ob npaug.

Hauv cov neeg mob uas mob raum tsis zoo, kev kho mob yog ua tiav los ntawm kev tswj raum.

Cov neeg mob yuav tsum tau qhia tam sim ntawd qhia txog cov leeg tsis hnov ​​qhov mob, cia li nkees, lossis tsis muaj zog, tshwj xeeb tshaj yog tias nws nrog nws mob lossis kub taub hau.

Nrog saib xyuas

Cov neeg mob uas cuam tshuam los ntawm kev quav cawv thiab cov neeg mob uas tau hloov khoom nruab nrog cev tau raug qhia kom yauv mus rau kev kho mob Simlo nrog kev ceev faj heev.

Nws raug nquahu kom xyuam xim tseem nyob ntawm qhov pom ntawm cov mob sib kis, thaum hais tawm ntawm endocrine thiab cov teeb meem loj ntawm lub cev, nrog rau kev txhim kho ntawm txoj hlab ntsha hauv lub cev, kev ua txhaum ntawm cov dej-electrolyte sib npaug, thaum kev phais mob lossis raug mob.

Simlo kuj yuav tsum tau ua tib zoo saib xyuas los ntawm cov neeg mob hloov kho pob txha caj dab, nrog mob vwm lossis mob chua leeg. Thaum muaj qee yam ntawm cov kev mob tau hais tseg, nws raug nquahu kom noj cov tshuaj no tsuas yog qhia los ntawm kws kho mob.