Thioctacid - BV (Thioctacid - HR) cov lus qhia rau siv

Thioctacid BV: cov lus qhia rau kev siv thiab tshuaj xyuas

Lub npe Latin: Thioctacid

ATX Code: A16AX01

Cov khoom xyaw nquag: thioctic acid (thioctic acid)

Chaw tsim tshuaj paus: GmbH MEDA Raug (Tebchaws Yelemees)

Hloov kho cov lus piav qhia thiab yees duab: 10.24.2018

Cov nqi hauv khw muag tshuaj: los ntawm 1605 rubles.

Thioctacid BV yog ib qho tshuaj noj tshuaj metabolic nrog cov antioxidant cuam tshuam.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Thioctacid BV yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj coated nrog zaj duab xis txheej: ntsuab-daj, oblong biconvex (30, 60 lossis 100 pcs. Hauv tsaus iav lub khob, 1 lub raj mis hauv ib pob ntawv qhwv).

1 ntsiav tshuaj muaj:

• cov tshuaj nquag: thioctic (alpha-lipoic) acid - 0.6 g,
• Cov khoom xyaw pabcuam: magnesium stearate, hyprolose, qis-hloov hyprolose,
• zaj duab xis txheej muaj pes tsawg leeg: titanium dioxide, macrogol 6000, hypromellose, kua roj vanish raws indigo carmine thiab zas xim quinoline daj, talc.

Cov Tshuaj Hauv Tshuaj

Thioctacid BV yog cov tshuaj metabolic uas txhim kho cov hlab hlwb neurons, muaj cov kab mob hepatoprotective, hypocholesterolemic, hypoglycemic, thiab lipid-txo cov teebmeem.

Cov tshuaj ua haujlwm nquag ntawm cov tshuaj yog thioctic acid, uas muaj nyob hauv tib neeg lub cev thiab yog ib qho kev tiv thaiv tsis zoo. Raws li coenzyme, nws koom nrog oxidative phosphorylation ntawm pyruvic acid thiab alpha-keto acids. Tus txheej txheem ntawm kev ua ntawm thioctic acid yog ze rau cov txiaj ntsig biochemical ntawm cov vitamins B. Nws pab tiv thaiv cov hlwb los ntawm cov tshuaj lom los ntawm cov dawb radicals uas tshwm sim hauv cov txheej txheem metabolic, thiab neutralizes exogenous tshuaj lom cov tebchaw uas tau nkag hauv lub cev. Ua kom nce qib ntawm cov endogenous antioxidant glutathione, ua rau muaj qhov txo qis ntawm cov kev mob tshwm sim ntawm polyneuropathy.

Cov nyhuv synergistic ntawm thioctic acid thiab insulin yog qhov nce ntawm cov piam thaj siv.

Cov Tshuaj Pharmacokinetics

Qhov nqus ntawm thioctic acid los ntawm kev mob plab hnyuv (GIT) thaum muab qhov ncauj tshwm sim sai thiab ua kom tiav. Kev noj tshuaj nrog zaub mov tuaj yeem txo nws txoj kev nqus. C_max (qhov siab tshaj plaws) hauv cov ntshav ntshav tom qab noj cov tshuaj ib zaug tiav tom qab 30 feeb thiab yog 0.004 mg / ml. Qhov tseeb txog kev tsis raug mob ntawm Thioctacid BV yog 20%.

Ua ntej nkag mus rau hauv cov kab mob rau hauv lub nruab nrog cev, thioctic acid yauv ua haujlwm ntawm thawj qhov kev nkag los ntawm lub siab. Lub hauv kev tseem ceeb ntawm nws cov metabolism yog oxidation thiab conjugation.

T_1/2 (Ib nrab-lub neej) yog 25 feeb.

Kev nqhis ntawm cov tshuaj nquag ua haujlwm Thioctacid BV thiab nws cov metabolites yog nqa tawm los ntawm lub raum. Nrog tso zis, 80-90% ntawm cov tshuaj tawm los.

Cov lus qhia rau kev siv Thioctacid BV: txoj kev thiab ntau npaum li cas

Raws li cov lus qhia, Thioctacid BV 600 mg tau noj hauv lub plab khoob sab hauv, 0.5 teev ua ntej noj tshais, nqos tau tag nrho thiab haus dej kom ntau.

Cov tshuaj pom zoo: 1 pc. Ib hnub.

Muab cov ntaub ntawv soj ntsuam ua tau, rau kev kho mob ntawm cov mob hnyav ntawm polyneuropathy, thawj zaug kev tswj hwm ntawm kev daws thioctic acid rau kev tswj hwm ntshav (Thioctacid 600 T) yog ua tau rau lub sijhawm 14 mus rau 28 hnub, tom qab ntawd hloov chaw ntawm tus neeg mob mus rau kev noj tshuaj txhua hnub (Thioctacid BV).

Sab sij huam

• los ntawm lub plab zom mov: feem ntau - xeev siab, tsis tshua muaj - ntuav, mob hauv plab thiab plab hnyuv, raws plab, ua txhaum ntawm saj tsis zoo,
• los ntawm cov leeg hlwb: feem ntau - kiv taub hau,
• kev ua xua: tsis tshua muaj tshwm sim - khaus, tawm pob ntawm daim tawv nqaij, urticaria, anaphylactic ceeb,
• los ntawm lub cev tag nrho: qhov tsis tshua muaj tshwm sim - txo ntshav qabzib hauv lub ntsej muag, qhov tshwm sim ntawm cov tsos mob ntawm kev mob ntshav qab zib ua ib qho mob taub hau, tsis meej pem, nce tawm hws, thiab pom kev tsis zoo.

Noj ntau dhau

Cov tsos mob: tiv thaiv keeb kwm ntawm ib zaug ntawm 10-40 g ntawm thioctic acid, kev qaug cawv ntau yuav tshwm sim nrog cov kev mob tshwm sim xws li mob nriaj chua leeg, mob tsis meej pem, tsis txaus ntseeg nyob rau hauv cov kua qaub-hauv paus, lactic acidosis, mob hnyav los ntshav (nrog rau kev tuag).

Kev Kho Mob: Yog tias xav ntau dhau ntawm Thioctacid BV xav tias yog xav (ib koob tshuaj rau cov neeg laus ntau tshaj 10 ntsiav tshuaj, menyuam yaus ntau dua 50 mg rau 1 kg ntawm nws lub cev qhov hnyav), tus neeg mob yuav tsum tau mus pw hauv tsev kho mob sai nrog kev teem sijhawm kho mob. Yog tias tsim nyog, kev siv tshuaj tiv thaiv kev kho mob siv, kev kho mob thaum muaj xwm txheej ceev tswj kom tau lub luag haujlwm ntawm cov kabmob tseem ceeb.

Cov lus qhia tshwj xeeb

Txij li thaum ethanol yog qhov muaj kev pheej hmoo rau kev txhim kho polyneuropathy thiab ua rau txo qis kev kho mob ntawm Thioctacid BV, kev haus cawv yog nruj me ntsis hauv cov neeg mob.

Hauv kev kho mob ntshav qab zib polyneuropathy, tus neeg mob yuav tsum tsim cov kev mob uas ua kom muaj kev saib xyuas ntawm qib siab ntawm cov piam thaj hauv cov ntshav.

Tso tawm daim ntawv, ntim thiab muaj pes tsawg leeg Thioctacid ® BV

Cov ntsiav tshuaj, zaj duab xis-coated daj-ntsuab, oblong, biconvex.

Tshwjxeeb: tsawg hloov chaw hyprolose - 157 mg, hyprolose - 20 mg, magnesium stearate - 24 mg.

Cov sib xyaw ua ke ntawm cov zaj duab xis txheej: hypromellose - 15.8 mg, macrogol 6000 - 4.7 mg, titanium dioxide - 4 mg, talc - 2.02 mg, txhuas cov kua roj vanish raws cov xim quinoline daj - 1,32 mg, kua roj vanish raws indigo carmine - 0.16 mg.

30 pcs - tsaus iav fwj (1) - pob khoom los ntawm cardboard.
60 pcs. - tsaus iav fwj (1) - pob khoom los ntawm cardboard.
100 pcs - tsaus iav fwj (1) - pob khoom los ntawm cardboard.

Yeeb tshuaj sib cuam tshuam

Nrog tib lub sijhawm siv Thioctacid BV:

• cisplatin - txo qis nws cov nyhuv kho,
• insulin, cov tshuaj tiv thaiv kab mob hypoglycemic - tuaj yeem txhim kho lawv cov txiaj ntsig, yog li ntawd, kev soj ntsuam cov ntshav ntawm cov ntshav qabzib yog qhov yuav tsum tau ua, tshwj xeeb tshaj yog thaum pib ntawm kev sib xyaw, yog tias tsim nyog, yuav tsum tau txo cov tshuaj hypoglycemic,
• ethanol thiab nws cov metabolites - ua rau qaug zog ntawm cov tshuaj.

Nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus kheej cov cuab yeej ntawm thioctic acid rau qhov khi ntawm cov hlau thaum ua ke nrog cov tshuaj muaj hlau, magnesium thiab lwm yam hlau. Nws raug nquahu kom lawv qhov kev nkag mus tau pauv mus rau yav tav su.

Kev tshuaj xyuas ntawm Thioctacide BV

Kev tshuaj xyuas ntawm Thioctacide BV feem ntau zoo dua. Cov neeg mob ntshav qab zib qhia tias cov ntshav qab zib thiab ntshav qab zib yuav txo qis, muaj kev noj qab haus huv zoo tiv thaiv keeb kwm ntawm kev siv lub sijhawm ntev. Ib qho kev tshaj tawm ntawm cov tshuaj yog qhov kev tso tawm sai ntawm thioctic acid, uas pab txhawm rau ua kom cov txheej txheem metabolic thiab tshem tawm cov rog tsis txaus los ntawm lub cev, qhov hloov pauv ntawm carbohydrates rau hauv lub zog.

Ib txoj hauv kev kho kom zoo yog sau tseg thaum siv tshuaj yaj yeeb rau kev kho mob siab, kho cov leeg mob hlwb, rog dhau. Piv nrog analogues, cov neeg mob qhia tias qis dua qhov tshwm sim ntawm qhov tsis xav txog.

Hauv qee tus neeg mob, noj cov tshuaj tsis muaj kev cia siab txog kev txo qis cov roj lossis pab txhawb kev txhim kho mob urticaria.

Pharmacological kev txiav txim

Cov tshuaj txiav txim hlau. Thioctic (lip-lipoic) acid yog pom nyob rau hauv tib neeg lub cev, qhov twg nws ua raws li coenzyme hauv oxidative phosphorylation ntawm pyruvic acid thiab alpha-keto acids. Thioctic acid yog qhov tshuaj tiv thaiv kab mob endogenous; raws li lub tshuab biochemical ntawm kev nqis tes ua, nws nyob ze rau B vitamins.

Thioctic acid pab tiv thaiv cov hlwb los ntawm cov tshuaj lom neeg los ntawm cov dawb radicals uas tshwm sim hauv cov txheej txheem metabolic, nws kuj neutralizes exogenous lom cov sib txuas uas tau nkag mus rau hauv lub cev. Thioctic acid nce qhov kev xav txog ntawm cov tshuaj tua kabmob muaj sia ntau kawg, uas ua rau txo qis ntawm qhov mob hnyav ntawm cov tsos mob polyneuropathy.

Cov tshuaj muaj hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effect, txhim kho trophic neurons. Kev txiav txim siab ntawm thioctic acid thiab insulin ua tau los ntawm kev siv cov piam thaj ntau ntxiv.

Kev sib xyaw, kev piav qhia, daim ntawv thiab ntim ntawm cov tshuaj

Koj tuaj yeem yuav cov tshuaj hauv ob hom sib txawv:

• Kev npaj ntawm ncauj "Thioctacid BV" (ntsiav tshuaj). Cov lus qhia rau kev siv hais tias nws muaj daim duab convex, zoo li lub plhaub daj lossis nrog lub zuaj ntsuab. Ntawm kev muag, xws li cov ntsiav tshuaj tuaj hauv lub raj mis ntawm 30 daim. Lub zog tshuaj ntawm cov cuab yeej no yog thioctic acid. Cov tshuaj noj kuj tseem muaj cov ntsiab lus ntxiv hauv daim ntawv ntawm qis-hloov hydroxypropyl cellulose, magnesium stearate, hydroxypropyl cellulose, hypromellose, macrogol 6000, quinoline daj aluminium ntsev, titanium dioxide, talc thiab indigo carmine txhuas ntsev.
• Txoj kev daws teeb meem "Thioctacid BV" 600. Cov lus qhia rau kev siv xov xwm tias daim ntawv no ntawm cov tshuaj yog npaj rau kev txhaj tshuaj rau leeg. Cov tshuaj ntshiab yog daj thiab muaj nyob hauv qhov tsaus iav ampoules. Nws lub cev ua haujlwm tseem yog thioctic acid. Raws li cov tshuaj ntxiv, cov dej lim thiab trometamol siv.

Kws Tshuaj

Hauv tib neeg lub cev, thioctic acid ua lub luag haujlwm ntawm coenzyme, uas koom nrog oxidative cov cuam tshuam ntawm phosphorylation ntawm alpha-keto acids, nrog rau pyruvic acid. Tsis tas li ntawd, nws yog ib qho tshuaj antioxidant endogenous. Los ntawm nws cov ntsiab cai ntawm kev coj ua (biochemical), qhov kev tivthaiv no ze li sai tau ntawm B vitamins.

Raws li cov kws tshaj lij, thioctic acid tiv thaiv cov hlwb los ntawm cov tshuaj lom los ntawm cov dawb radicals uas tau tsim thaum lub cev metabolism. Nws kuj pab mus rau neutralize exogenous lom lub tebchaw uas tau nkag mus rau hauv tib neeg lub cev.

Cov tshuaj muaj nqi

Cov tshuaj yeeb yaj kiab "Thioctacid BV 600 yog dab tsi?" Cov lus qhia rau kev siv qhia tias thioctic acid muaj peev xwm nce ntxiv qhov muaj zog ntawm cov tshuaj tiv thaiv kab mob zoo li glutathione. Cov txiaj ntsig zoo sib xws ua rau txo qis qhov tseem ceeb ntawm qhov mob ntawm polyneuropathy.

Nws yog tsis yooj yim sua kom tsis txhob hais tias cov tshuaj hauv cov lus nug muaj qhov ua kom tsis muaj ntshav qab zib, mob siab, mob ntshav qab zib thiab mob ntshav qis. Nws kuj tseem tuaj yeem txhim kho trophic neurons.

Cov teebmeem synergistic ntawm thioctic acid thiab insulin nce kev siv piam thaj.

Cov Yuav Tsum Muaj

Vim tias tsis muaj qhov kev paub txaus nrog kev siv cov cuab yeej no thiab cov kev tshawb fawb soj ntsuam, nws tsis tshua pom zoo kom taw nws rau leej niam thiab tus poj niam cev xeeb tub.

Puas yog nws ua tau rau muab tshuaj rau me nyuam "Thioctacid 600BV"? Txwv tsis pub siv cov tshuaj no rau menyuam yaus thiab tub ntxhais hluas. Tsis tas li, nws yuav tsum tsis txhob siv thaum muaj kev fab tshuaj rau ib yam ntawm cov khoom siv.

Kev phiv tshuaj

Nrog kev tswj hwm sab hauv ntawm cov tshuaj, tus neeg mob tuaj yeem txhim kho qhov tsis xav zoo li:

• kev ua xua nyob rau hauv daim ntawv ua pob thiab khaus khaus ntawm daim tawv nqaij, nrog rau urticaria,
• phiv los ntawm cov hnyuv hauv plab (zawv plab, xeev siab, mob thiab ntuav).

Raws li rau daim ntawv txhaj tshuaj, nws feem ntau ua rau:

• daim tawv nqaij ua pob, anaphylactic ceeb thiab khaus,
• ua pa nyuaj thiab ua rau muaj kev nkag siab ntau ntxiv (intracranial),
• los ntshav, cramps, teeb meem tsis pom kev, thiab ntshav me me.

Cov tshuaj txhaum kev cai ntau dhau

Yog tias cov koob pom zoo ntawm cov tshuaj tau dhau los, tus neeg mob yuav tsim muaj cov tsos mob xws li nriaj, mob lactic acidosis, tso ntshav tawm thiab tsis nco qab lawm.

Thaum soj ntsuam cov kev tawm tsam zoo li no, koj yuav tsum sab laj nrog kws kho mob, thiab tseem ua rau qaug dab peg hauv tus neeg raug mob, muab nws enterosorbents thiab yaug koj plab. Tus neeg mob yuav tsum tau txais kev txhawb kom txog thaum lub tsheb thauj neeg mob tuaj txog.

Dosage daim ntawv

600 mg zaj duab xis-coated ntsiav tshuaj

Ib ntsiav tshuaj muaj

cov tshuaj nquag - thioctic acid (alpha lipoic) 600 mg,

tus zam: tsis tshua muaj cov hloov hydroxypropyl cellulose, hydroxypropyl cellulose, magnesium stearate,

hypromellose, macrogol 6000, titanium dioxide (E 171), talc, quinoline daj (E 104), indigo carmine (E 132).

Cov ntsiav tshuaj, zaj duab xis-coated daj-ntsuab, oblong nyob rau hauv cov duab nrog ib tug biconvex nto.

Analogs thiab nqi

Hloov cov tshuaj zoo li Thioctacid BV nrog cov tshuaj hauv qab no: Berlition, Alpha Lipon, Dialipon, Tiogamma.

Raws li rau tus nqi, nws tuaj yeem sib txawv rau cov ntawv sib txawv thiab cov tuam ntxhab. Tus nqi ntawm cov ntsiav tshuaj daim ntawv ntawm "Thioctacid BV" (600 mg) yog li 1700 rubles rau 30 daim. Ib cov tshuaj nyob rau hauv daim ntawv ntawm kev daws teeb meem tuaj yeem tau yuav rau 1,500 rubles (rau 5 daim).

Kev tshuaj xyuas txog cov tshuaj

Raws li koj paub, cov tshuaj "Thioctacid BV" yog npaj rau cov neeg uas muaj teeb meem ntawm kev mob plab zom mov tsis txaus. Kev tshuaj xyuas ntawm cov neeg mob txog cov ntsiav tshuaj daim ntawv tsis meej xwm. Raws li lawv cov lus ceeb toom, qhov cuab yeej no muaj txiaj ntsig zoo. Tab sis hmoov tsis zoo, ntsiav tshuaj feem ntau ua rau muaj kev phiv tshuaj, uas qhia tau lawv tus kheej hauv txoj kev xeev siab, urticaria, thiab qee zaus txawm tias yog kub thiab hloov pauv ntawm tus neeg mob lub siab thiab lub siab.

Tam sim no koj paub cov tshuaj "Thioctacid BV 600" sawv cev li cas. Cov lus qhia rau kev siv, tus nqi ntawm cov tshuaj tau piav saum toj no.

Kev tshuaj xyuas txog cov kev hais daws tau tawm tsis yog tsuas yog cov neeg mob uas siv nws cov ntsiav tshuaj, tab sis kuj yog cov uas tau tsim cov tshuaj rau kev txhaj tshuaj.

Raws li cov lus ceeb toom ntawm cov neeg zoo li no, phiv nrog kev tswj hwm tshuaj ntawm cov tshuaj muaj tsawg dua. Ntxiv mus, lawv yuav tsis tshaj tawm tau hais zoo li thaum noj tshuaj.

Yog li, nws tuaj yeem pom zoo tias "Thioctacid BV" yog cov cuab yeej siv tau zoo los tsim los tawm tsam cov tsos mob ntawm polyneuropathy uas tau tshwm sim tom qab haus dej haus cawv ntev ntev los yog tiv thaiv keeb kwm ntawm ntshav qab zib mellitus.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Nrog rau kev tswj hwm qhov ncauj, muaj kev nqus sai ntawm thioctic (alpha-lipoic) acid hauv lub cev. Vim tias kev faib tawm sai dhau ntawm cov ntaub so ntswg, ib nrab-lub neej ntawm thioctic (alpha-lipoic) acid hauv cov ntshav ntshav yog kwv yees li 25 feeb. Qhov siab tshaj plaws ntshav ntawm 4 μg / ml tau ntsuas 0.5 teev tom qab kev tswj hwm ntawm 600 mg ntawm alpha lipoic acid. Kev tshem tawm ntawm cov tshuaj tshwm sim feem ntau los ntawm lub raum, 80-90% - nyob rau hauv daim ntawv ntawm metabolites.

Cov Tshuaj Hauv Tshuaj

Thioctic (alpha-lipoic) acid yog qhov kev tiv thaiv tsis zoo thiab ua cov coenzyme hauv oxidative decarboxylation ntawm alpha-keto acids. Hyperglycemia tshwm sim los ntawm cov ntshav qab zib ua rau cov tsub zuj zus ntawm cov piam thaj nyob rau hauv cov roj ntsha matrix cov roj ntsha thiab cov kev tsim ntawm lub npe hu ua "cov khoom lag luam kawg ntawm glycation." Tus txheej txheem no ua rau muaj kev txo qis rau cov ntshav endoneural thiab ua kom cov kabmob hypoxia-ischemia, uas yog ua ke nrog ntau ntxiv ntawm cov pa oxygen dawb radicals, uas ua rau kev puas tsuaj rau peripheral qab haus huv thiab txo cov antioxidants xws li glutathione.

Tsuas tshuaj thiab tswj hwm

Noj 1 lub tshuaj Thioctacid 600BV ib hnub ib zaug hauv ib koob, 30 feeb ua ntej noj mov thawj zaug.

Noj hauv plab khoob, tsis ntxo thiab haus dej ntau. Kev sib xyaw nrog kev noj zaub mov kom tsawg yuav txo qis kev nqus ntawm alpha lipoic acid.

Lub sijhawm kho yog txiav txim siab los ntawm tus kws kho mob.

Cov tshuaj sib cuam tshuam

Muaj qhov txo qis ntawm qhov ua haujlwm ntawm cisplatin thaum muab cov sijhawm ua ke nrog thioctacid. Cov tshuaj yuav tsum tsis txhob kho ib txhij nrog hlau, magnesium, poov tshuaj, lub sijhawm sib nrug ntawm cov koob tshuaj no yuav tsum yog tsawg kawg 5 teev. Txij li thaum cov ntshav qab zib ua kom qis qis ntawm cov tshuaj insulin lossis cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj tuaj yeem ua kom zoo dua, kev saib xyuas cov ntshav qab zib tas li yog qhov kev xav, tshwj xeeb tshaj yog thaum pib kho nrog Thioctacid 600BV. Yuav kom zam tau cov tsos mob ntawm tus mob ntshav qab zib, nws yog ib qhov tsim nyog yuav tau ua tib zoo saib xyuas qib ntshav qab zib hauv cov ntshav.

Daim Ntawv Tso Npe Sau Npe

MEDA Pharma GmbH & Co. KG, Lub Tebchaws Yelemees

Chaw nyob ntawm lub koom haum uas lees txais ntawv thov nyiaj los ntawm cov neeg siv khoom ntawm cov khoom lag luam zoo hauv Republic of Kazakhstan Cov sawv cev ntawm MEDA Tshuaj Switzerland Switzerland GmbH hauv koom pheej ntawm Kazakhstan: Almaty, 7 Al-Farabi Ave., PFC "Nurly Tau", lub tsev 4 A, chaw haujlwm 31, tel. 311-04-30, 311-52-49, xov tooj cua / 277-77-32