Cov lus qhia rau kev siv tshuaj, tshuaj yeeb dawb, tshuaj xyuas

Npe sau npe: P N015030 / 05-031213
Hom Lub Npe: Augmentin®
Thoob ntiaj teb uas tsis yog tus tswv lossis cov pab pawg npe: amoxicillin + clavulanic acid.

Daim ntawv muab cov: cov ntsiav tshuaj-coated ntsiav tshuaj.

Cov tshuaj sib xyaw ua ke (1 ntsiav tshuaj)
Yam tshuaj muaj zog:
Amoxicillin trihydrate nyob rau hauv cov nqe lus ntawm amoxicillin 250.0 mg,
Poov tshuaj clavulanate nyob rau hauv cov nqe lus ntawm clavulanic acid 125.0 mg.
Cov muaj tswv yim:
ntsiav tshuaj tub ntxhais: magnesium stearate, sodium carboxymethyl hmoov txhuv nplej siab, colloidal silicon dioxide, microcrystalline cellulose,
zaj duab xis txheej ntsiav tshuaj: titanium dioxide, hypromellose (5 cP), hypromellose (15 cP), macrogol-4000, macrogol-6000, dimethicone.

Qhov sib piv ntawm cov nquag

Dosage form Qhov sib piv ntawm cov nquag ua haujlwm Amoxicillin, mg (hauv daim ntawv ntawm amoxicillin trihydrate) Clavulanic acid, mg (hauv daim ntawv ntawm potassium clavulanate)
Ntsiav tshuaj 250 mg / 125 mg 2: 1 250 125

Kev piav qhia
Cov yeeb yaj kiab xim-xev yog oval los ntawm dawb mus rau yuav luag dawb hauv cov xim nrog cov ntawv sau "AUGMENTIN" ntawm ib sab. Cov ntsiav tshuaj los ntawm daj dawb mus rau yuav luag dawb hauv pob txha tawg.

Pharmacological pawg
Tshuaj tua kab mob, penicillin semisynthetic + beta-lactamase inhibitor.

ATX Code: J01CR02

PHARMACOLOGICAL COV CAI

Cov Tshuaj Hauv Tshuaj
Mechanism ntawm kev ua
Amoxicillin yog cov tshuaj tua kab mob ntau tshaj ib nrab hnub nrog kev ua si tiv thaiv ntau yam kab mob gram-positive thiab gram-tsis zoo. Tib lub sijhawm, amoxicillin tiv thaiv kev puas tsuaj los ntawm beta-lactamases, thiab yog li ntawd cov spectrum ntawm kev ua ntawm amoxicillin tsis txuas ntxiv mus rau cov kab mob me me uas tsim cov enzyme no.
Clavulanic acid, beta-lactamase inhibitor yam ntxwv cuam tshuam txog penicillins, muaj peev xwm tsis muaj peev xwm tsis muaj peev xwm ua ntau yam ntawm beta-lactamases pom muaj nyob rau hauv penicillin thiab cephalosporin tiv taus cov kab mob me me. Clavulanic acid muaj kev ua tau zoo txaus los tiv thaiv plasmid beta-lactamases, uas feem ntau txiav txim siab qhov tawm tsam ntawm cov kab mob, thiab tsis muaj kev tiv thaiv zoo tiv thaiv cov chromosomal beta-lactamases hom 1, uas tsis yog tshuaj tiv thaiv los ntawm clavulanic acid.
Muaj cov clavulanic acid nyob hauv kev npaj Augmentin® tiv thaiv amoxicillin los ntawm kev puas tsuaj los ntawm cov enzymes - beta-lactamases, uas tso cai rau nthuav cov tshuaj tua kab mob ntawm amoxicillin.
Cov hauv qab no yog hauv kev ua haujlwm hauv vitro ntawm amoxicillin nrog clavulanic acid.
Cov kab mob feem ntau cuam tshuam rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid
Gram-zoo aerobes
Bacillus anthracis
Enterococcus faecalis
Listeria monocytogenes
Nocardia asteroides
Streptococcus pyogenes1,2
Tus kab mob Streptococcus agalactiae 1.2
Streptococcus spp. (lwm beta hemolytic streptococci) 1,2
Staphylococcus aureus (methicillin rhiab) 1
Staphylococcus saprophyticus (methicillin rhiab)
Coagulase-negative staphylococci (rhiab rau methicillin)
Gram-zoo anaerobes
Clostridium spp.
Peptococcus niger
Peptostreptococcus magnus
Peptostreptococcus micros
Peptostreptococcus spp.
Gram-negative aerobes
Bordetella mob hnoos qhuav
Haemophilus infuenzae1
Helicobacter pylori
Moraxella catarrhalis1
Neisseria gonorrhoeae
Pasteurella multocida
Vibrio mob raws plab
Gram-negative anaerobes
Bacteroides fragilis
Bacteroides spp.
Capnocytophaga spp.
Eikenella corrodens
Fusobacterium nucleatum
Fusobacterium spp.
Porphyromonas spp.
Prevotella spp.
Lwm yam
Borrelia burgdorferi
Leptospira icterohaemorrhagiae
Treponema pallidum
Cov kab mob rau cov uas kis tau tiv thaiv ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid yuav ntxim
Gram-negative aerobes
Escherichia coli1
Klebsiella oxytoca
Klebsiella pneumoniae1
Klebsiella spp.
Proteus mirabilis
Proteus vulgaris
Proteus spp.
Salmonella spp.
Shigella spp.
Gram-zoo aerobes
Corynebacterium spp.
Enterococcus faecium
Tus kab mob Streptococcus pneumoniae 1.2
Cov pab pawg Streptococcus Viridans
Cov kab mob uas ib txwm muaj peev xwm tiv thaiv kev sib txuas ntawm amoxicillin nrog clavulanic acid
Gram-negative aerobes
Acinetobacter spp.
Citrobacter freundii
Cov kab mob Enterobacter spp.
Hafnia alvei
Legionella pneumophila
Morganella morganii
Providencia spp.
Pseudomonas spp.
Serratia spp.
Stenotrophomonas maltophilia
Yersinia enterocolitica
Lwm yam
Chlamydia mob ntsws dej
Chlamydia psittaci
Chlamydia spp.
Coxiella burnetii
Mycoplasma spp.
1 - rau cov kab mob no, kev soj ntsuam kev tau txais txiaj ntsig ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid tau pom hauv cov kev tshawb fawb soj ntsuam.
2 - hom kab mob ntawm cov kab mob no tsis tsim cov beta-lactamases.
Kev nkag siab nrog amoxicillin monotherapy qhia qhov zoo sib xws mus rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid.
Cov Tshuaj Pharmacokinetics
Xuas
Ob lub cev sib xyaw ntawm Augmentin® kev npaj, amoxicillin thiab clavulanic acid, tau sai thiab tag nrho los ntawm kev mob plab zom mov (GIT) tom qab kev tswj hwm qhov ncauj. Qhov nqus ntawm cov khoom nquag ntawm kev npaj ntawm Augmentin® yog qhov zoo tshaj thaum noj cov tshuaj thaum pib noj mov.
Cov tshuaj pharmacokinetic ntawm amoxicillin thiab clavulanic acid, tau txais hauv kev tshawb fawb sib txawv, thaum cov neeg tuaj yeem yoo mov sai:
- 1 ntsiav tshuaj ntawm Augmentin®, 250 mg / 125 mg (375 mg),
- 2 ntsiav tshuaj ntawm cov tshuaj Augmentin®, 250 mg / 125 mg (375 mg),
- 1 ntsiav tshuaj ntawm Augmentin®, 500 mg / 125 mg (625 mg),
- 500 mg ntawm amoxicillin,
- 125 mg ntawm clavulanic acid.
Yooj yim pharmacokinetic

Cov Tshuaj Tshuaj Koob Tshuaj (mg) Cmax (mg / l) Tmax (h) AUC (mg × h / l) T1 / 2 (h)
Amoxicillin nyob rau hauv muaj pes tsawg leeg ntawm cov tshuaj Augmentin®
Augmentin®, 250 mg / 125 mg 250 3.7 1.1 10.9 1.0
Augmentin®, 250 mg / 125 mg, 2 ntsiav tshuaj 500 5.8 1.5 20.9 1.3
Augmentin® 500 mg / 125 mg 500 6.5 1.5 23.2 1.3
Amoxicillin 500 mg 500 6.5 1.3 19.5 1.1
Clavulanic acid nyob rau hauv kev sib xyaw ntawm cov tshuaj Augmentin®
Augmentin®, 250 mg / 125 mg 125 2.2 1.2 6.2 1.2
Augmentin®, 250 mg / 125 mg, 2 ntsiav tshuaj 250 4.1 1.3 11.8 1.0
Clavulanic acid, 125 mg 125 3.4 0.9 7.8 0.7
Augmentin®, 500 mg / 125 mg 125 2.8 1.3 7.3 0.8

Cmax - ntau qhov ntshav siab tshaj plaws.
Tmax - lub sijhawm kom mus txog qhov siab tshaj plaws ntshav plasma.
AUC yog thaj chaw hauv qab kev cia siab-lub sijhawm nkhaus.
T1 / 2 - ib nrab-lub neej.
Thaum siv cov tshuaj Augmentin®, ntshav ntau ntawm amoxicillin zoo ib yam li cov tshuaj noj ntawm qhov ncauj ntawm sib piv ntawm amoxicillin.
Kev xa Khoom
Ib yam li kev sib xyaw ua ke ntawm amoxicillin nrog clavulanic acid, kev kho mob ntau ntawm amoxicillin thiab clavulanic acid muaj nyob rau hauv ntau cov ntaub so ntswg thiab cov kua dej interstitial (nyob rau hauv lub qog, cov nqaij hauv lub plab, tawv nqaij, adipose thiab cov leeg nqaij, synovial thiab peritoneal kua, kua tsib, thiab purulent tawm). Cov.
Amoxicillin thiab clavulanic acid muaj qhov tsis muaj zog ntawm kev cog lus rau cov ntshav protein. Cov kev tshawb fawb pom tau tias kwv yees li 25% ntawm tag nrho cov nyiaj clavulanic acid thiab 18% ntawm amoxicillin hauv ntshav plasma khi rau cov ntshav plasma protein.
Hauv kev tshawb nrhiav tsiaj, tsis muaj kev txuam ntawm lub Cheebtsam ntawm Augmentin® kev npaj hauv ib qho khoom hauv nruab nrog.
Amoxicillin, zoo li feem ntau penicillins kis mus rau niam mis. Cov kab ntawm clavulanic acid kuj tseem yuav pom nyob hauv niam cov kua mis. Dhau ntawm qhov muaj peev xwm ntawm kev nkag siab, mob raws plab thiab candidiasis ntawm lub qhov ncauj ua pa ntawm lub qhov ncauj, tsis muaj lwm yam tsis zoo ntawm amoxicillin thiab clavulanic acid rau kev noj qab haus huv ntawm cov menyuam noj niam mis.
Cov kev tshawb fawb tsiaj yug me nyuam tau pom tias amoxicillin thiab clavulanic acid hla qhov chaw teeb meem. Txawm li cas los xij, tsis muaj qhov tshwm sim tsis zoo ntawm tus me nyuam hauv plab.
Kev zom zaub mov
10-25% ntawm thawj zaug koob tshuaj amoxicillin raug ntiab tawm los ntawm ob lub raum ua lub zog tsis haum (penicilloic acid). Clavulanic acid tau dav dav rau 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid thiab 1-amino-4-hydroxy-butan-2-ib thiab tau tawm los ntawm lub raum, los ntawm kev zom cov pa zom zaws, ntxiv rau nrog cov huab cua tas sijhawm hauv daim ntawv carbon dioxide.
Chaw Sau Ntawv
Zoo li lwm yam rau penicillins, amoxicillin raug cais tawm feem ntau los ntawm lub raum, thaum clavulanic acid los ntawm ob lub raum thiab ntxiv kev ua haujlwm. Txog 60-70% ntawm amoxicillin thiab kwv yees li 40-65% ntawm clavulanic acid raug tso tawm los ntawm lub raum tsis hloov hauv thawj 6 teev tom qab kev teem 1 lub tshuaj ntawm cov tshuaj Augmentin® hauv kev tsim cov tshuaj yeeb yaj kiab-ntsiav tshuaj, 250 mg / 125 mg lossis 500 mg / 125 mg. Cov.
Kev tswj hwm tib lub sijhawm ntawm probenecid qeeb qeeb ua rau qhov tsis pom kev ntawm amoxicillin, tab sis tsis yog clavulanic acid (saib ntu "Kev cuam tshuam nrog lwm cov tshuaj").

INDICATIONS RAU SIV

Cov kab mob kis tau los ntawm cov kab mob me me uas nkag rau amoxicillin / clavulanic acid:
• mob ENT, xws li mob ua mob tonsillitis, mob ntsws, mob otitis, feem ntau los ntawm tus kab mob Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis thiab Streptococcus pyogenes.
• Cov kab mob ua pa tsawg dua, xws li ua kom mob ntsws txhaws ntev, mob ntsws, thiab mob ntsws, feem ntau los ntawm tus kab mob Streptococcus pneumoniae, Haemophilus inflluenzae, thiab Moraxella catarrhalis.
• Kab mob Urogenital, xws li cystitis, mob urethritis, pyelonephritis, poj niam lub cev ua paug, feem ntau yog tshwm sim los ntawm hom kab mob Enterobacteriaceae (feem ntau Escherichia coli), Staphylococcus saprophyticus thiab hom Enterococcus, nrog rau mob gonorrhea tshwm sim los ntawm Neisseria gonorrhoeae.
• Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos, feem ntau tshwm sim los ntawm Staphylococcus aureus, Streptococcus pyogenes, thiab hom ntawm cov genus Bacteroides.
• Kev kis mob ntawm cov pob txha thiab pob qij txha, xws li osteomyelitis, feem ntau tshwm sim los ntawm Staphylococcus aureus, yog tias muaj kev kho mob ntev yog tsim nyog.
• Lwm yam kev kis mob sib xyaw (piv txwv li, septic rho menyuam tawm, mob plab rau leeg, seps plab hauv plab) yog txoj haujlwm kho mob.
Kev kis mob tshwm sim los ntawm cov kab mob me me uas nkag rau amoxicillin tuaj yeem kho nrog Augmentin®, vim tias amoxicillin yog ib qho ntawm nws cov khoom xyaw tseem ceeb.

TSWJ SIB LWM

• Kev ua haujlwm tsis haum rau beta-lactams, xws li penicillins thiab cephalosporins lossis lwm yam tshuaj,
• Cov mob daj ntseg yav dhau los lossis lub siab ua kom lub siab ua haujlwm nrog keeb kwm ntawm amoxicillin / clavulanic acid,
• cov menyuam yaus hnub nyoog qis dua 12 xyoos rau daim ntawv noj tshuaj no.

DAIM NTAWV THOV KEV TXHAUM CAI THIAB THAUM MUAJ NCUAV QAB ZE QAB ZIB

Cev xeeb tub
Hauv kev tshawb fawb ntawm kev ua me nyuam hauv cov tsiaj, qhov ncauj thiab kev tswj hwm ntawm Augmentin® tsis ua rau muaj teebmeem teratogenic.
Hauv kev tshawb fawb ib zaug hauv cov poj niam nrog lub cev ua ntej lub cev xoos xoos, nws tau pom tias prophylactic kev siv tshuaj kho mob yuav cuam tshuam nrog kev pheej hmoo ntawm necrotizing enterocolitis hauv cov menyuam mos. Zoo li txhua yam tshuaj, Augmentin® tsis pom zoo rau siv thaum cev xeeb tub, tshwj tsis yog tias muaj kev cia siab rau tus niam tshaj qhov muaj feem yuav ua rau muaj menyuam hauv plab.
Lub sijhawm pub mis niam
Augmentin® tuaj yeem siv thaum pub mis. Dhau ntawm qhov muaj peev xwm ntawm kev nkag siab, mob raws plab, thiab candidiasis ntawm lub qhov ncauj cov leeg ua kab mob cuam tshuam nrog kev nkag mus ntawm cov nyiaj ntawm cov khoom xyaw tseem ceeb ntawm cov tshuaj no rau cov niam mis, tsis muaj lwm yam kev tsis zoo tshwm sim hauv cov menyuam mos niam mis. Yog tias muaj qhov tshwm sim tsis zoo hauv cov menyuam yaus noj niam mis, nws yuav tsum tsis ua mus ntxiv.

KHAWV KOOB THIAB KEV COB QHIA

Txog kev tswj hwm qhov ncauj.
Cov tshuaj noj rau lub cev yog tsim tshwj xeeb raws lub hnub nyoog, lub cev qhov hnyav, lub raum kev ua haujlwm ntawm tus neeg mob, nrog rau qhov mob hnyav heev.
Txo kom txo tau qhov muaj peev xwm ua mob plab hnyuv twm thiab kom muaj qhov nqus tau zoo, kom cov tshuaj yuav tsum noj thaum noj mov.
Qhov kawm tsawg kawg ntawm cov tshuaj tua kab mob yog 5 hnub.
Txoj kev kho yuav tsum tsis txhob txuas ntxiv ntev dua 14 hnub yam tsis muaj tshuaj xyuas qhov xwm txheej kho mob.
Yog tias tsim nyog, nws muaj peev xwm los ua cov kauj ruam kho mob (thawj zaug, kev tswj hwm txoj kev npaj ntawm Augmentin a nyob rau hauv ib daim ntawv tshuaj noj; hmoov rau kev npaj cov tshuaj rau kev tswj hwm nrog kev hloov mus tom qab Augmentin® hauv kev kho mob qhov ncauj).
Nws yuav tsum nco ntsoov tias 2 ntsiav tshuaj ntawm Augmentin® 250 mg / 125 mg tsis sib npaug rau ib ntsiav tshuaj ntawm Augmentin® 500 mg / 125 mg.
Cov neeg loj thiab menyuam yaus hnub nyoog 12 xyoos thiab laus dua lossis hnyav 40 kg lossis ntau dua
1 ntsiav tshuaj 250 mg / 125 mg 3 zaug ib hnub rau kev kis mob me me mus rau mob hnyav.
Hauv kev kis mob hnyav (suav nrog kev mob raum thiab mob rov zoo li qub, mob ntsws thiab ib puag ncig kev ua pa ntawm txoj hlab ntsws), lwm txoj kev noj tshuaj ntawm Augmentin® yog kev pom zoo.
Cov pab pawg neeg tshwj xeeb
Cov me nyuam qis dua 12 xyoos los hnyav dua 40 kg
Hauv cov menyuam hnub nyoog qis dua 12 xyoos, nws raug nquahu kom siv lwm cov tshuaj noj ntawm Augmentin® kev npaj.
Cov neeg laus cov neeg mob
Tsis tas yuav tsum kho npaum li cas. Hauv cov neeg mob laus uas lub raum lub raum tsis ua haujlwm, qhov koob tshuaj yuav tsum tau kho raws li tau piav qhia saum toj no rau cov neeg laus uas lub raum tsis ua haujlwm.
Cov neeg mob uas lub raum tsis ua hauj lwm zoo
Kev kho ntawm cov tshuaj ntau npaum li cas yog raws li qhov siab tshaj plaws kev pom zoo ntawm amoxicillin thiab creatinine tshem tawm tus nqi.

Creatinine tshem tawm Augmentin® kev txhaj tshuaj ntau dua
> 30 ml / min Tsis tas yuav muab kho kom haum
10-30 ml / min 1 ntsiav tshuaj 250 mg / 125 mg (rau kev sib kis me me mus rau mob) 2 zaug ib hnub

Cov ntawv tso tawm, ntau yam thiab npe ntawm Augmentin

Tam sim no, Augmentin muaj nyob rau hauv peb yam hauv qab no:
1. Augmentin
2. Augmentin EU,
3. Augmentin SR.

Tag nrho peb ntawm cov ntau ntawm Augmentin yog cov lag luam tawm ntawm tib cov tshuaj tua kab mob nrog tib cov kev cuam tshuam, kev ntsuas thiab cov cai ntawm kev siv. Tsuas yog qhov sib txawv ntawm kev ua lag luam ntau yam ntawm Augmentin yog qhov ntau npaum ntawm cov tshuaj nquag thiab daim ntawv tso tawm (ntsiav tshuaj, ncua kev kawm, hmoov rau kev daws rau kev txhaj tshuaj). Cov kev sib txawv no ua rau koj xaiv qhov zoo tshaj plaws ntawm cov tshuaj rau qee kis. Piv txwv li, yog tias ib tus neeg laus yog rau qee qhov tsis muaj peev xwm nqos tau Augmentin ntsiav tshuaj, nws tuaj yeem siv Augmentin EU kev ncua, thiab lwm yam.

Feem ntau, txhua hom tshuaj no tsuas yog hu ua "Augmentin," thiab txhawm rau paub meej qhov txhais tau meej, lawv tsuas ntxiv lub npe ntawm cov tshuaj thiab ntau npaum, piv txwv li, Augmentin raug tshem tawm 200, Augmentin ntsiav tshuaj 875, thiab lwm yam.

Muaj ntau hom Augmentin muaj nyob hauv cov ntawv hauv qab no:
1. Augmentin:

Qhov ncauj ntsiav tshuaj
Hmoov rau kev tshem tawm ntawm qhov ncauj
Hmoov rau kev daws rau kev txhaj tshuaj.

2. Augmentin EU:

Hmoov rau kev ncua rau kev tswj hwm qhov ncauj.

3. Augmentin SR:

Cov qauv tshuaj tso tawm nrog rau kev ua yeeb yam ntev.

Nyob rau hauv lub neej txhua hnub, rau kev tsim qauv ntawm ntau yam thiab ntau hom ntawm Augmentin, feem ntau cov ntawv luv luv tau siv, suav nrog lo lus "Augmentin" thiab qhov ntsuas ntawm daim ntawv los yog cov tshuaj ntau npaum li cas, piv txwv li, raug ncua ntawm Augmentin, Augmentin 400, thiab lwm yam.

Kev sib xyaw ntawm Augmentin

Cov sib xyaw ua ke ntawm txhua yam thiab muab cov tshuaj ntawm Augmentin li cov nquag ua ke suav nrog ob yam hauv qab no:

Amoxicillin
Clavulanic acid.

Amoxicillin thiab clavulanic acid nyob rau ntau hom Augmentin muaj nyob hauv ntau qhov sib txawv thiab kev sib piv ntawm ib leeg, uas tso cai rau koj xaiv qhov zoo tshaj plaws ntawm cov tshuaj yeeb dej caw rau txhua yam kis mob thiab hnub nyoog ntawm ib tus neeg.

Amoxicillin yog cov tshuaj tua kab mob uas yog koom nrog pawg penicillin, uas muaj qhov kev txiav txim siab dav dav thiab ua rau muaj ntau cov kab mob pathogenic uas ua rau kis kab mob ntawm ntau yam plab hnyuv siab raum thiab tshuab. Tsis tas li ntawd, amoxicillin tau pom zoo zoo thiab tsis tshua muaj kev phiv, uas ua rau cov tshuaj tua kab mob no muaj kev nyab xeeb, siv tau thiab pom zoo rau siv txawm tias cov poj niam cev xeeb tub thiab cov menyuam mos.

Txawm li cas los xij, nws muaj ib qho tsis txaus ntseeg - kev tawm tsam amoxicillin nyob rau hauv ntau cov kab mob tom qab ob peb hnub ntawm kev siv, txij li cov microbes pib tsim cov tshuaj tshwj xeeb - lactamases uas rhuav tshem cov tshuaj tua kab mob. Qhov teeb meem no txwv txoj kev siv amoxicillin siv los kho tus kab mob.

Txawm li cas los xij, amoxicillin deficiency yog tshem tawm. clavulanic acid , uas yog qhov thib ob ntawm Augmentin. Clavulanic acid yog ib yam khoom uas ua rau lactamases ua los ntawm cov kab mob thiab, raws li, ua rau amoxicillin ua tau zoo txawm tias tawm tsam cov microbes uas yav dhau los ua tsis tau rau nws txoj haujlwm. Ntawd yog, clavulanic acid ua rau amoxicillin ua hauj lwm zoo tiv thaiv cov kab mob uas tiv thaiv nws txoj haujlwm, uas nthuav dav ntau ntawm kev siv cov tshuaj sib xyaw Augmentin.

Yog li, kev sib xyaw ntawm amoxicillin + clavulanic acid ua rau cov tshuaj tua kab mob ua tau zoo dua, nthuav dav nws cov yeeb yam ntawm kev ua thiab tiv thaiv kev txhim kho ntawm kev tawm tsam los ntawm cov kab mob.

Augmentin Dosage (rau cov neeg laus thiab cov menyuam yaus)

Txhua daim ntawv tshuaj ntawm Augmentin muaj ob qho tshuaj uas muaj sia - amoxicillin thiab clavulanic acid, yog li qhov ntau ntawm cov tshuaj tau qhia tsis yog los ntawm ib tus lej, tab sis los ntawm ob, piv txwv li, 400 mg + 57 mg, thiab lwm yam. Ntxiv mus, thawj tus lej ib txwm qhia txog amoxicillin ntau npaum li cas, thiab lub thib ob - clavulanic acid.

Yog li, Augmentin nyob rau hauv daim ntawv ntawm hmoov rau kev npaj ntawm kev daws rau kev txhaj tshuaj muaj nyob rau hauv qhov ntau thiab tsawg ntawm 500 mg + 100 mg thiab 1000 mg + 200 mg. Qhov no txhais tau hais tias tom qab diluting hmoov nrog dej, ib qho kev daws teeb meem tau txais uas muaj 500 mg lossis 1000 mg ntawm amoxicillin thiab, ntsig txog, 100 mg thiab 200 mg ntawm clavulanic acid. Hauv lub neej txhua hnub, cov ntaub ntawv tshuaj no feem ntau hu ua "Augmentin 500" thiab "Augmentin 1000", siv ib daim duab uas nthuav tawm cov ntsiab lus ntawm amoxicillin thiab rho tawm ntau npaum li cas ntawm clavulanic acid.

Augmentin nyob rau hauv cov hmoov sau rau kev npaj ntawm qhov ncauj ncua yog muaj nyob hauv peb qhov ntau: 125 mg + 31.25 mg rau 5 ml, 200 mg + 28.5 mg rau 5 ml thiab 400 mg + 57 mg rau 5 ml. Nyob rau hauv lub neej txhua hnub, kev tsim qauv ntawm tus nqi ntawm clavulanic acid feem ntau yog lawb tawm, thiab tsuas yog cov ntsiab lus ntawm amoxicillin yog qhia, vim tias qhov kev xam ntawm cov tshuaj noj yog ua tshwj xeeb rau cov tshuaj tua kab mob. Vim qhov no, kev tsim qauv luv luv ntawm kev ncua ntawm ntau yam tshuaj zoo li no: "Augmentin 125", "Augmentin 200" thiab "Augmentin 400".

Txij li thaum lub sijhawm Augmentin raug tshem tawm yog siv rau hauv menyuam yaus qis dua 12 xyoos, feem ntau nws hu ua "Cov Menyuam Augmentin". Raws li, qhov ntau npaum li cas ntawm lub txim yog hu ua menyuam mos. Qhov tseeb, qhov ntau npaum li cas ntawm kev ncua yog tus qauv thiab tej zaum yuav siv tau rau cov neeg laus uas lub cev tsis tshua muaj ceeb thawj, tab sis vim yog qhov tseem ceeb ntawm kev siv cov tshuaj no rau cov menyuam yaus, lawv hu ua menyuam yaus.

Cov tshuaj Augmentin muaj nyob rau hauv peb qhov tshuaj: 250 mg + 125 mg, 500 mg + 125 mg thiab 875 mg + 125 mg, uas nws txawv hauv cov ntsiab lus ntawm amoxicillin xwb. Yog li no, hauv lub neej txhua hnub, ntsiav tshuaj feem ntau yog hais luv, qhia tias tsuas yog noj tshuaj amoxicillin: "Augmentin 250", "Augmentin 500" thiab "Augmentin 875". Tus nqi qhia ntawm amoxicillin muaj nyob hauv ib lub Augmentin ntsiav tshuaj.

Augmentin EC muaj nyob rau hauv cov hmoov ntawv rau kev npaj ntawm kev ncua nyob hauv ib qho tshuaj - 600 mg + 42.9 mg rau 5 ml. Qhov no txhais tau hais tias 5 ml ntawm qhov kev ua tiav kev ua tiav muaj 600 mg ntawm amoxicillin thiab 42.9 mg ntawm clavulanic acid.

Augmentin SR muaj nyob rau hauv daim ntawv foos nrog nrog kev siv tshuaj ntau npaum - 1000 mg + 62.5 mg. Qhov no txhais tau hais tias ib ntsiav tshuaj muaj 1000 mg ntawm amoxicillin thiab 62.5 mg ntawm clavulanic acid.

Daim ntawv tso tawm

Augmentin ntsiav tshuaj sib txawv txawv ntawm oval duab, plhaub dawb thiab dawb lossis daj-dawb xim ntawm pob txha tawg. Ib sab ntawm cov ntsiav tshuaj muaj ib kab uas cov tshuaj tuaj yeem tsoo. Ntawm txhua sab ntawm cov tshuaj muaj cov tsiaj ntawv loj A thiab C. Cov ntsiav tshuaj raug muag hauv hlwv ntawm 7 lossis 10 daim, thiab hauv ib pob tuaj yeem muaj 14 lossis 20 ntsiav tshuaj.

Cov tshuaj yog tsim tawm hauv lwm cov ntaub ntawv:

Vials ntawm hmoov los ntawm kev npaj los txhawm rau. Daim ntawv no tau nthuav tawm hauv ntau txoj kev xaiv, nyob ntawm qhov ntau npaum li cas ntawm amoxicillin rau ib 5 milliliters ntawm cov tshuaj - 125 mg, 200 mg lossis 400 mg.
Hmoov vials uas yog diluted rau cov tshuaj txhaj leeg. Lawv kuj tseem muaj nyob hauv ob qhov tshuaj - 500mg + 100mg thiab 1000mg + 200mg.

Cov nquag ua haujlwm ntawm Augmentin ntsiav tshuaj yog ob lub tebchaw:

Amoxicillin, uas tau nthuav tawm hauv cov tshuaj ua daim ntawv trihydrate.
Clavulanic acid, uas muaj nyob hauv cov ntsiav tshuaj hauv daim ntawv ntawm poov tshuaj ntsev.

Nyob ntawm qhov ntau npaum li cas ntawm cov khoom xyaw no hauv ib ntsiav tshuaj, cov tshuaj hauv qab no tau txawv:

250 mg + 125 mg
500 mg + 125 mg
875 mg + 125 mg

Hauv kev teeb tsa no, thawj tus lej qhia tias yog amoxicillin ntau npaum li cas, thiab lub cim thib ob qhia cov ntsiab lus ntawm clavulanic acid.

Ntu cov khoom siv sab hauv ntawm cov ntsiav tshuaj yog colloidal silicon dioxide, MCC, magnesium stearate thiab carboxymethyl hmoov txhuv nplej siab sodium. Lub plhaub tshuaj yog tsim los ntawm macrogol (4000 thiab 6000), dimethicone, hypromellose (5 thiab 15 cps) thiab titanium dioxide.

Lub hauv paus ntsiab lus ntawm kev khiav haujlwm

Amoxicillin tam sim no hauv cov tshuaj muaj cov kab mob bactericidal ua rau ntau hom microbes, tab sis nws tsis cuam tshuam cov kab mob me me uas muaj peev xwm ua kom tsis pub muaj cov beta-lactamases, txij li cov enzymes rhuav tshem nws. Ua tsaug rau qhov kev tsis txaus ntseeg beta-lactamase clavulanic acid, qhov kev pom ntawm kev ua ntawm cov ntsiav tshuaj tau nthuav dav. Vim li no, kev sib xyaw ntawm cov tebchaw zoo li no muaj peev xwm ua tau zoo dua li cov tshuaj muaj tsuas yog amoxicillin.

Augmentin nquag tawm tsam staphylococci, listeria, gonococci, pertussis bacillus, peptococcus, streptococcus, hemophilic bacillus, helicobacter, clostridia, leptospira thiab ntau yam kab mob me.

Txawm li cas los xij, cov kab mob xws li Proteus, Salmonella, Shigella, Escherichia, pneumococcus thiab Klebsiella tuaj yeem tiv taus cov tshuaj tua kab mob no. Yog tias tus menyuam muaj tus kabmob virus, mycoplasma, chlamydia, entero-lossis cytrobacter, pseudomonas thiab qee yam kabmob microbes, cov kev kho mob nrog Augmentin yuav tsis.

Ntsiav tshuaj Augmentin yog tshuaj rau:

Kev mob pob txha
Tonsillite
Mob ntsws los yog mob ntsws,
Purulent otitis media
Pyelonephritis, cystitis thiab lwm yam kev kis mob ntawm cov neeg mob,
Kabmob hnoos hawbpob
Gonorrhea
Kab mob Streptococcal / staphylococcal mob ntawm daim tawv nqaij lossis cov nqaij mos,
Periodontitis thiab lwm yam kev mob odontogenic,
Mob ntsws hnoos qeev
Sib koom tes
Osteomyelitis
Tus mob cholecystitis
Sepsis thiab lwm yam mob tshwm sim los ntawm cov tshuaj yeeb tshuaj lom.

Kuv muaj pes tsawg xyoo uas kuv tuaj yeem tau txais?

Kev kho mob nrog Augmentin ntsiav tshuaj pom zoo rau cov menyuam yaus hnub nyoog 12 xyoos. Nws kuj tseem tuaj yeem hais rau cov menyuam yau yog tias tus menyuam qhov hnyav tshaj 40 phaus. Yog tias koj xav muab cov tshuaj zoo li no rau tus menyuam nrog lub cev nyhav qis dua thiab thaum muaj hnub nyoog ntxov (piv txwv li, thaum muaj hnub nyoog 6 xyoo), siv kev ncua. Xws li cov kua ua tau siv txawm tias hauv cov menyuam mos.

Cov kev cai dav dav rau kev coj ua txhua daim ntawv thiab ntau yam ntawm Augmentin

Cov ntsiav tshuaj yuav tsum tau nqos tag nrho, tsis ntxo, tsis tom los yog tsoo lwm qhov, thiab ntxuav nrog me me ntawm cov dej (ib nrab khob).

Ua ntej noj qhov ncua kev kawm ntawv, ntsuas qhov ntsuas yuav tsum tau siv uas siv lub ntsuas phoo tshwj xeeb lossis koob txhaj tshuaj zuam. Qhov kev ncua yog muab ntawm qhov ncauj, nqos tus ntsuas uas tsim nyog ntsuas los ntawm lub ntsuas ntsuas. Cov menyuam yaus uas yog vim li cas tsis tuaj yeem haus cov dej raug tshem tawm, nws raug nquahu kom dilute nws nrog dej hauv qhov sib piv ntawm 1: 1, tom qab nchuav cov nyiaj tsim nyog los ntawm lub ntsuas ntsuas rau hauv lub khob lossis lwm lub khob. Tom qab siv tas, lub hau ntsuas lossis cov koob txhaj tshuaj yuav tsum yaug nrog cov dej huv.

Txhawm rau kom txo qis tsis xis nyob thiab phiv los ntawm lub plab zom mov, nws raug nquahu kom noj cov ntsiav tshuaj thiab muab ncua thaum pib noj mov. Txawm li cas los xij, yog tias qhov no ua tsis tau li cas los xij, tom qab ntawd cov ntsiav tshuaj tuaj yeem noj lub sijhawm twg los ntawm kev saib xyuas zaub mov, vim tias cov zaub mov tsis cuam tshuam rau qhov tshwm sim ntawm cov tshuaj.

Kev txhaj tshuaj Augmentin yog muab rau txoj leeg ntshav. Koj tuaj yeem hno cov tshuaj sib tov (los ntawm cov koob txhaj tshuaj) lossis infusion ("dropper"). Intramuscular cov thawj coj ntawm cov tshuaj tsis raug tso cai! Kev daws rau kev txhaj tshuaj yog npaj los ntawm hmoov tam sim ntawd ua ntej tswjhwm thiab tsis khaws txawm tias nyob hauv tub yees.

Kev tswj hwm ntawm cov ntsiav tshuaj thiab kev ncua, nrog rau kev tswj hwm ntawm cov dej ntawm Augmentin kev daws teeb meem, yuav tsum tau nqa tawm ntawm kev ua haujlwm tsis tu ncua. Piv txwv li, yog tias koj yuav tsum tau noj cov tshuaj ob zaug hauv ib hnub, ces koj yuav tsum tswj kev ncua 12 teev ib zaug nyob nruab nrab ntawm koob tshuaj. Yog tias nws yuav tsum tau coj Augmentin 3 zaug hauv ib hnub, tom qab ntawd koj yuav tsum ua qhov no txhua 8 teev, sim ua kom nruj me ntsis saib ntu no, thiab lwm yam.

Yam tsawg kawg nkaus pub rau kev siv ib daim ntawv thiab ntau yam ntawm Augmentin yog 5 hnub. Qhov no txhais tau tias koj tsis tuaj yeem noj cov tshuaj tsawg dua 5 hnub. Qhov siab kawg tau pub ntev tshaj plaws ntawm kev siv ib daim ntawv thiab ntau yam ntawm Augmentin yam tsis tau rov kuaj dua yog 2 lub lis piam. Ntawd yog, tom qab kev kuaj pom tau ua tsis muaj kev kuaj zaum ob, koj tuaj yeem siv cov tshuaj kom tsis pub ntev tshaj 2 lub lis piam. Yog hais tias, thaum lub sij hawm ntawm txoj kev kho, kev kuaj mob rov qab tau nqa tawm, uas qhia txog qhov ua tau zoo, tab sis qeeb, kev hloov kho, tom qab ntawd, raws li cov txiaj ntsig no, lub sijhawm ntawm Augmentin tswj hwm tuaj yeem nce ntxiv mus rau 3 lossis txawm 4 lub lis piam.

Yog tias tsim nyog, koj tuaj yeem nqa tawm cov kauj ruam kev kho mob, uas muaj nyob rau tom qab siv kev siv tshuaj thiab ntsiav tshuaj lossis kev ncua nyob sab hauv. Hauv qhov no, ua ntej kom tau txais cov txiaj ntsig ntau, Augmentin kev txhaj tshuaj yog ua, thiab tom qab ntawd lawv hloov mus rau kev noj tshuaj lossis ncua kev kawm.

Koj yuav tsum tsis txhob hloov ntau cov ntawv thiab kev noj tshuaj ntawm Augmentin nrog txhua lwm, piv txwv li, tsis txhob siv ib ntsiav tshuaj ntawm 500 mg + 125 mg, noj 2 ntsiav tshuaj ntawm 250 mg + 125 mg, thiab lwm yam. Cov kev hloov pauv tsis tuaj yeem ua tau, vim tias ntau txoj kev siv ntau yam ntawm tib hom tshuaj tsis sib thooj. Txij li thaum muaj kev xaiv dav ntawm Augmentin dosages, koj yuav tsum xaiv qhov yog, thiab tsis siv qhov uas twb muaj lawm, sim hloov nws nrog qhov tsim nyog.

Cov Yuav Tsum Muaj

Cov ntsiav tshuaj tsis raug muab rau cov menyuam yaus uas muaj lub siab tawv rau ib qho twg ntawm lawv cov khoom xyaw. Tsis tas li, cov tshuaj yog contraindicated yog tias tus menyuam yaus ua xua rau lwm yam tshuaj tua kab mob, penicillins lossis cephalosporins. Yog tias tus neeg mob me me muaj kev ua tsis zoo ntawm daim siab lossis lub raum, kev siv Augmentin yuav tsum muaj kev saib xyuas kev noj qab haus huv thiab kev hloov kho nyob ntawm cov txiaj ntsig ntawm kev ntsuam xyuas.

Peb xav kom koj saib ib daim vis dis aus ntawm Dr. Komarovsky txog yam tshuaj uas yuav tsum tau muaj hauv tsev uas muaj menyuam yaus thiab yuav siv lawv li cas.

Sab sij huam

Tus me nyuam lub cev tuaj yeem teb rau kev txais tos ntawm Augmentin:

Cov tsos mob ntawm kev tsis haum tshuaj, xws li urticaria lossis tawv nqaij khaus.
Nrog qhov tso quav xoob, xeev siab, lossis txhaws ntuav.
Hloov pauv hauv cov naj npawb ntawm cov ntshav, piv txwv, leukocytopenia thiab thrombocytopenia. Tsawg tsawg zaus, cov tshuaj provokes anemia, agranulocytosis thiab lwm yam kev hloov.
Qhov tshwm sim ntawm candidiasis ntawm daim tawv nqaij lossis cov qog ua kua.
Ntxiv kev ua haujlwm ntawm daim siab enzymes.
Kiv taub hau lossis mob taub hau.

Qee zaum, kev kho mob nrog cov tshuaj tua kab mob no tuaj yeem ua rau qaug dab peg, stomatitis, colitis, anaphylaxis, kev ntxhov siab tsis zoo, mob lub raum thiab lwm cov kev tsis zoo. Yog tias lawv tshwm sim hauv menyuam yaus, cov ntsiav tshuaj yuav tsum tau muab tso tseg tam sim ntawd.

Cov lus qhia rau kev siv

Augmentin regimen hauv cov ntsiav tshuaj muaj kev cuam tshuam los ntawm tus neeg mob lub cev qhov hnyav thiab hnub nyoog, nrog rau kev ua kom mob nyav ntau dhau, nrog rau lub raum ua haujlwm.
Txhawm rau cov tshuaj kom ua rau muaj kev mob tshwm sim tsawg dua los ntawm kev mob plab, nws raug nquahu kom haus nws nrog zaub mov (thaum pib noj mov). Yog tias qhov no ua tsis tau, koj tuaj yeem noj tshuaj ntsiav txhua lub sijhawm, vim kev zom zaub mov tsis cuam tshuam rau nws qhov nqus.
Cov tshuaj tau muab tshuaj rau tsawg kawg 5 hnub, tab sis tsis pub ntev tshaj 2 lub lis piam.
Nws yog ib qho tseem ceeb kom paub tias ib qho 500mg + 125mg ntsiav tshuaj tsis tuaj yeem hloov nrog ob 250mg + 125mg ntsiav tshuaj. Lawv kev noj tshuaj yog tsis sib npaug.

Qhov kev xaiv ntawm daim ntawv ntau npaum ntawm cov tshuaj

Tsis hais txog ntawm qhov kis ntawm tus kab mob sib kis, cov neeg laus thiab menyuam yaus hnub nyoog 12 xyoos lossis muaj lub cev qhov hnyav tshaj 40 kg yuav tsum noj Augmentin tsuas yog hauv daim ntawv tshuaj (txhua yam tshuaj - 250/125, 500/125 lossis 875/125) lossis ncua nrog muab tshuaj ntau dua 400 mg + 57 mg Kev raug ncua nrog cov tshuaj ntawm 125 mg thiab 200 mg yuav tsum tsis txhob noj los ntawm cov neeg laus thiab menyuam yaus hnub nyoog dhau 12 xyoos, vim tias cov tshuaj amoxicillin thiab clavulanic acid nyob hauv lawv tsis suav nrog kev suav nrog tus lej ntawm kev ua kom zoo thiab faib tawm ntawm cov tshuaj hauv cov ntaub so ntswg.

Cov menyuam yaus hnub nyoog qis dua 12 xyoos lossis muaj lub cev qhov hnyav tsawg dua 40 kg yuav tsum siv Augmentin tsuas yog tshem tawm. Hauv qhov xwm txheej no, cov menyuam mos hnub nyoog qis dua 3 hlis tuaj yeem tsuas yog muab ncua kev kawm ntawv nrog qhov tshuaj ntau npaum li 125 / 31.25 mg. Hauv cov menyuam yaus uas muaj hnub nyoog tshaj 3 hlis, nws tau tso cai siv rau kev ncua nrog ib qho tshuaj ntawm cov khoom nquag. Vim tias qhov tseeb tias ncua Augmentin yog rau cov menyuam yaus, nws feem ntau hu tau tias yooj yim “Cov me nyuam Augmentin,” uas tsis qhia txog daim ntawv tshuaj noj (ncua kev kawm). Cov tshuaj ntawm qhov ncua kev kawm raug suav txhua tus raws hnub nyoog thiab lub cev qhov hnyav ntawm tus menyuam.

Kev txhaj tshuaj Augmentin tuaj yeem siv rau cov menyuam yaus hnub nyoog thiab rau cov neeg laus, tom qab suav tus neeg noj tshuaj los ntawm lub cev hnyav.

Kev ncua Augmentin EU thiab Augmentin SR cov ntsiav tshuaj tuaj yeem noj rau cov laus thiab menyuam yaus hnub nyoog 12 xyoos lossis hnyav tshaj lub cev hnyav dua 40 kg.

Cov kev cai npaj rau kev npaj ncua kev kawm ntawv Augmentin thiab Augmentin EU

Koj tsis tuaj yeem nchuav tag nrho cov hmoov los ntawm lub raj mis thiab faib nws, piv txwv li, ua 2, 3, 4 lossis ntau qhov chaw, thiab cais cov feem tau sib cais. Kev tsoo zoo li no ua rau cov tshuaj tsis raug thiab kev faib tsis sib luag ntawm cov tshuaj lom neeg rau hauv qhov chaw ntawm cov hmoov, vim nws tsis tuaj yeem sib tov nws thiaj li tias cov lwg me me ntawm cov nquag ua kom sib txig sib luag faib thoob plaws qhov ntim. Qhov no, nyeg, ua rau tsis muaj txiaj ntsig ntawm qhov raug ncua tau npaj los ntawm ib nrab ntawm cov hmoov, thiab kev siv ntau dhau ntawm kev ncua ua los ntawm lwm feem ntawm hmoov. Ntawd yog, tom qab tsoo, hauv ib feem ntawm cov hmoov muaj peev xwm muaj ob peb yam tshuaj, thiab lwm qhov, ntawm qhov tsis sib xws, ntau dhau. Raws li qhov tshwm sim, kev ncua tawm ua los ntawm cov hmoov uas muaj cov ntsiab lus tsawg ntawm cov khoom sib txuas yuav muaj qhov qis qis dua ntawm amoxicillin thiab clavulanic acid ntau dua li tsim nyog. Thiab lwm qhov kev ncua, npaj los ntawm cov hmoov uas muaj ntau ntawm amoxicillin thiab clavulanic acid, yuav, ntawm qhov tsis sib xws, muaj ntau dhau ntawm cov ntsiab lus nquag.

Qhov ncua kev kawm ntawv tau npaj nrog kev haus tshuaj ntawm cov txheej txheem nquag raws li hauv qab no:
1. 60 ml ntawm cov dej npau muab tso rau hauv lub raj mis hmoov (qhov dej ntim tuaj yeem ntsuas nrog ib rab koob).
2. Ntsia rau ntawm lub hau taub hau thiab co nws kom khov kho kom txog thaum hmoov tau tag.
3. Tom qab ntawv tso lub raj mis li 5 feeb rau ib qho chaw tiaj.
4. Yog tias tom qab qhov no, cov kab tawm tsis txaus ntawm cov hmoov sib sau rau hauv qab, tom qab ntawd nchuav lub thawb rov qab sib zog thiab rov muab nws tso rau ib qho chaw tiaj rau 5 feeb.
5. Thaum, tom qab 5 feeb ntawm kev tawm tsam, tsis muaj ib qho hmoov hauv qab ntawm qhov vial, qhib lub hau thiab ntxiv cov dej rhaub kom txias rau lub cim.

Nws yuav tsum nco ntsoov tias rau kev npaj ncua kev ncua nrog qhov ntau npaum ntawm 125 / 31.25, dej ntau ntxiv (kwv yees li 92 ml) yuav tsum ntau dua li kev noj tshuaj 200 / 28.5 thiab 400/57 (kwv yees li 64 ml). Yog li, rau thawj zaug kev sib cais, nws yog ib qho tsim nyog yuav tsum tsis txhob ntau tshaj 60 ml dej (nws tau tso cai rau nchuav me ntsis, tab sis tsis ntau, yog li ntawd tom qab tau txais kev ncua nws tsis pom tias nws qib siab dua lub cim rau ntawm lub raj mis).

Kev tshem tawm tiav tuaj yeem khaws cia rau hauv tub yees (yam tsis muaj khov) rau ib lub lim tiam, tom qab ntawd txhua qhov seem tsis siv yuav tsum muab pov tseg. Yog tias cov chav kawm ntawm kev kho mob ntev dua 7 hnub, tom qab ib lub lim tiam ntawm kev khaws cia, koj yuav tsum muab pov tseg cov seem ntawm cov tshuaj qub thiab npaj ib qho tshiab.

Cov kev cai npaj rau kev npaj cov tshuaj Augmentin tov

Txhawm rau npaj cov tshuaj rau kev txhaj tshuaj, cov ntsiab lus ntawm lub raj mis nrog hmoov hauv qhov ntau npaum ntawm 500/100 (0.6 g) hauv 10 ml dej yuav tsum tau diluted, thiab lub raj mis nrog qhov tshuaj ntau npaum li 1000/200 (1.2 g) hauv 20 ml dej. Txhawm rau ua qhov no, 10 lossis 20 ml dej rau kev txhaj tshuaj yog kos rau hauv cov phwj, tom qab uas xav tau lub raj mis nrog hmoov yog qhib. Ib nrab dej los ntawm cov phwj (uas yog 5 los sis 10 ml) tau ntxiv rau hauv lub thauv thiab shaken zoo kom txog thaum cov hmoov yaj tag. Tom qab ntawd ntxiv cov dej ntxiv thiab co zoo dua. Tom qab qhov no, txoj kev ua tiav lawm tso rau sawv ntsug li 3 mus rau 5 feeb. Yog tias cov kua nplaum ntawm cov kua tshuaj tsis muaj kua tshwm rau hauv qab ntawm lub thawb tom qab daws, sib zog nchuav lub khob ntim rov qab nrawm dua Thaum twg tsis muaj cov hmoov me me tshwm rau hauv qab ntawm lub vial tom qab daws ntev li 3 txog 5 feeb, cov tshuaj yuav pom tau tias npaj txhij thiab siv.

Yog tias Augmentin tau muab tshuaj rau hauv lub dav hlau, tom qab ntawd qhov kev txiav txim siab tsim nyog los ntawm lub thauv mus rau hauv cov tshuaj tsis haum thiab txhaj tshuaj kom maj mam dhau 3 mus rau 4 feeb. Rau cov dav hlau tswj kev lag luam, ib qho kev daws teeb meem yuav tsum npaj kom txhij tam sim ntawd ua ntej siv. Qhov siab tshaj plaws pub rau lub sijhawm ntawm cov tshuaj tiav ua ntej kev txhaj tshuaj rau hauv lub zog tsis pub tshaj 20 feeb.

Yog hais tias Augmentin yuav muab tshuaj rau hauv cov qauv ntawm cov dej ntws tawm, tom qab ntawd cov ntsiab lus ntawm lub vial (tag nrho cov kev daws teeb meem) yog nchuav rau hauv cov kua dej ua kua uas twb tau dhau los hauv qhov system (dropper). Ntxiv mus, ib qho kev daws teeb meem nrog ib qho tshuaj yeeb dej caw ntawm 500/100 yog diluted nrog 50 ml ntawm infusion kua, thiab ib qho kev daws teeb meem nrog qhov ntau npaum ntawm 1000/200 - 100 ml ntawm cov kua dej ua kua. Tom qab ntawd tag nrho cov ntim ntawm cov tshuaj tov yog txhaj dropwise rau 30 txog 40 feeb.

Raws li qhov ua kua nqus dej, koj tuaj yeem siv cov tshuaj hauv qab no:

Dej rau kev txhaj tshuaj
Lub nplhaib
Cov tshuaj saline daws
Tshuaj nrog cov poov tshuaj sodium thiab sodium chlorides,
Cov kua nplaum tov
Dextran
Kev daws sodium bicarbonate.

Npaj tov rau Txoj kev lis ntshav tuaj yeem khaws cia rau 3 mus rau 4 teev.

Kev ncua Augmentin (Augmentin 125, Augmentin 200 thiab Augmentin 400) - cov lus qhia rau kev siv rau menyuam yaus (nrog kev muab xam)

Ua ntej siv, koj yuav tsum xaiv cov hmoov uas muaj txoj kev siv tshuaj thiab npaj rau kev ncua. Kev tshem tawm tas yuav tsum tau muab khaws cia rau hauv tub yees, tsis raug saib kom khov, ntev txog 7 hnub. Yog tias koj xav noj nws ntau tshaj li ib lub lim tiam, tom qab ntawd cov seem ntawm cov raug tshem tawm qub uas muab cia rau hauv lub tub yees yuav tsum tau muab pov tseg rau 8 hnub thiab ib qho tshiab yuav tsum tau npaj.

Ua ntej txhua tus txais tos, nws yog ib qho tsim nyog kom co lub vial nrog rau kev ncua, thiab tsuas yog tom qab ntawd, hu rau tus nqi uas yuav tsum tau siv uas siv lub taub hau ntsuas los yog cov koob txhaj muaj ib qho uas muaj kev sib faib. Tom qab siv txhua zaug, yaug lub hau thiab koob txhaj tshuaj nrog dej huv.

Qhov kev ncua yuav tuaj yeem hno ncaj qha los ntawm lub ntsuas ntsuas lossis yav tas los nchuav rau hauv lub thawv me, piv txwv li, khob, thiab lwm yam. Nws raug nquahu kom nchuav qhov kev ncua ntawv uas tau kos rau hauv cov koob txhaj tshuaj rau hauv rab diav lossis lub khob. Yog tias vim qee qhov nws nyuaj rau tus menyuam yaus nqos kev tshem tawm huv, tom qab ntawv ntsuas rau ib koob nkaus xwb tuaj yeem ntxiv dej nrog dej hauv qhov sib piv ntawm 1: 1. Hauv qhov no, koj tsis tuaj yeem ceev cov hmoov nrog ob zaug dej ntau. Ib qho kev ncua yuav tsum tau diluted ua ntej txhua koob thiab tsuas yog tus nqi uas tsim nyog nyob rau hauv ib zaug.

Cov tshuaj Augmentin hauv txhua kis yog xam ib tus zuj zus raws li lub cev qhov hnyav, hnub nyoog thiab mob hnyav ntawm tus menyuam. Hauv qhov no, tsuas yog amoxicillin coj los rau kev suav, thiab clavulanic acid tsis quav ntsej. Nws yuav tsum nco ntsoov tias cov menyuam yaus hnub nyoog qis dua 2 xyoos yuav tsum tsuas yog muab ncua rau Augmentin 125 / 31.5. Thiab cov menyuam yaus hnub nyoog ntau dua ob xyoos tuaj yeem raug ncua nrog ib qho tshuaj ntawm cov tshuaj yeeb dej caw (Augmentin 125, 200 thiab 400).

Cov me nyuam qis dua 3 hli kev noj tshuaj txhua hnub ntawm Augmentin ncua kev kawm yuav tsum tau muab xam raws li qhov sib piv ntawm 30 mg ntawm amoxicillin rau 1 kg. Tom qab ntawd txhais qhov ntau npaum li cas ntawm mg hauv milliliters, cov txiaj ntsig txhua hnub tau muab faib 2 thiab muab rau tus menyuam ob zaug ib hnub twg txhua 12 teev. Xav txog ib qho piv txwv ntawm kev laij qhov koob tshuaj Augmentin 125 / 31.25 kev ncua ntawv rau tus menyuam hnub nyoog 1 hlis nrog lub cev hnyav txog 6 kg. Yog li, qhov tshuaj rau nws txhua hnub rau nws yog 30 mg * 6 kg = 180 mg. Tom ntej no, koj yuav tsum xam seb muaj pes tsawg milliliters ntawm kev ncua ntawm 125 / 31.25 muaj 180 mg ntawm amoxicillin. Ua li no, peb suav qhov kev faib ua feem:
125 mg hauv 5 ml (qhov no yog qhov kev ncua tsis suav zoo raws li tau tshaj tawm los ntawm cov khw)
180 mg hauv X (x) ml.

Los ntawm cov kev sib piv peb suav qhov sib npaug: X = 180 * 5/125 = 7.2 ml.

Ntawd yog, qhov kev noj tshuaj txhua hnub ntawm Augmentin rau ib hlis tus menyuam yaus nrog lub cev nyhav txog 6 kg yog muaj nyob hauv 7.2 ml ntawm kev ncua nrog ib koob tshuaj 125 / 31.25. Txij li thaum tus menyuam yuav tsum raug muab ncua ob zaug hauv ib hnub, tom qab ntawd faib 7.2 / 2 = 3.6 ml. Yog li tus menyuam yuav tsum tau muab 3.6 ml ntawm kev ncua ob zaug nyob rau ib hnub.

Cov menyuam muaj 3 hlis txog 12 xyoos xam qhov ntau ntawm cov tshuaj ncua kev ncua ntawv tau ua raws lwm cov cim, tab sis kuj tseem coj mus rau hauv lub cev qhov hnyav thiab qhov mob hnyav ntawm tus kab mob. Yog li, qhov tshuaj txhua hnub rau kev ncua ntawm ntau qhov ntau yog xam los ntawm cov kev sib piv hauv qab no:

Ncua Kev Kawm Ntawv 125 / 31.25 - suav seb qhov noj ntau npaum li cas raws li ntawm 20 - 40 mg rau 1 kg ntawm huab hwm coj,
Ncua Kev Kawm 200 / 28.5 thiab 400/57 - xam qhov ntau npaum li cas hauv qhov piv ntawm 25 - 45 mg rau 1 kg ntawm huab hwm coj.

Nyob rau tib lub sijhawm, tsis tshua muaj kev sib cais (20 mg rau 1 kg rau kev ncua ntawm 125 mg thiab 25 mg rau 1 kg rau kev ncua 200 mg thiab 400 mg) raug coj los suav txhua hnub ntawm Augmentin rau kev kho mob ntawm daim tawv nqaij thiab cov nqaij mos, nrog rau cov mob tonsillitis. Thiab kev sib piv siab (40 mg / 1 kg rau kev ncua ntawm 125 mg thiab 45 mg / 1 kg rau kev ncua ntawm 200 mg thiab 400 mg) yog coj los suav cov tshuaj txhua hnub rau kev kho mob ntawm txhua lwm yam kab mob (otitis media, sinusitis, mob ntsws, mob ntsws, osteomyelitis, thiab lwm yam). .).

Ib qho ntxiv, rau cov menyuam yaus ntawm cov hnub nyoog no, txoj cai hauv qab no yuav tsum nco ntsoov - kev ncua kev kawm nrog qhov siab ntawm 125 / 31.5 tau muab peb zaug hauv ib hnub txhua 8 teev, thiab kev ncua nrog kev noj ntau npaum li 200 / 28.5 thiab 400/57 tau muab ob zaug ib hnub ntawm kev ncua sij hawm. thaum 12 teev sawv ntxov. Raws li, los txiav txim siab ntau npaum li cas muab ncua kev kawm muab rau tus menyuam, ua ntej, raws li tus qauv sib piv qhia saum toj no, kev noj tshuaj txhua hnub ntawm Augmentin hauv mg yog xam, thiab tom qab ntawd nws hloov mus rau hauv milliliters ntawm kev ncua nrog ib lossis lwm qhov kev xav. Tom qab ntawd, cov tau txais ml yog faib ua 2 lossis 3 koob tshuaj ib hnub.

Xav txog ib qho piv txwv ntawm xam qhov ntau npaum li cas ntawm kev ncua ntawv rau cov menyuam yaus hnub nyoog ntau dua 3 hlis. Yog li, tus menyuam yaus lub cev nyhav li 20 kg tiv thaiv tus mob tonsillitis. Yog li, nws xav siv sijhawm ncua 125 mg ntawm 20 mg rau 1 kg lossis ncua 200 mg thiab 400 mg ntawm 25 mg rau 1 kg. Peb suav pes tsawg mg rau yam muaj txiaj ntsig uas tus me nyuam xav tau nyob hauv kev ncua ntawm txhua qhov kev xav:
1. Ncua Kev Kawm Ntawv 125 / 31.25: 20 mg * 20 kg = 400 mg ib hnub,
2. Raug tshem tawm 200 / 28.5 thiab 400/57: 25 mg * 20 kg = 500 mg ib hnub.

Tom ntej no, peb suav pes tsawg milliliters ntawm kev ncua kev kawm muaj 400 mg thiab 500 mg ntawm amoxicillin, ntsig txog. Ua li no, peb suav qhov tsim nyog.

Rau qhov ncua kev kawm ntawv nrog qhov siab ntawm 125 / 31.25 mg:
400 mg hauv X ml
125 mg hauv 5 ml, X = 5 * 400/125 = 16 ml.

Rau qhov ncua kev kawm ntawv nrog qhov siab ntawm 200 / 28.5:
500 mg hauv X ml
200 mg hauv 5 ml, X = 5 * 500/200 = 12.5 ml.

Rau qhov ncua kev kawm ntawv nrog qhov siab ntawm 400/57 mg:
500 mg hauv X ml
400 mg hauv 5 ml, X = 5 * 500/400 = 6.25 ml.

Qhov no txhais tau hais tias rau tus menyuam lub cev muaj lub cev hnyav txog 10 kg raug kev txom nyem los ntawm tonsillitis, kev noj tshuaj rau txhua hnub ntawm kev ncua ntawm 125 mg yog 16 ml, ncua kev kawm 200 mg - 12.5 ml thiab ncua 400 mg - 6.25 ml. Tom ntej no, peb faib cov milliliters ntawm qhov nyiaj ib hnub rau kev ncua rau 2 lossis 3 koob tshuaj ib hnub. Rau qhov muab ncua kev ncua ntawm 125 mg, faib los ntawm 3 thiab tau txais: 16 ml / 3 = 5.3 ml. Rau kev ncua, 200 mg thiab 400 mg tau faib ua 2 thiab peb tau txais: 12.5 / 2 = 6.25 ml thiab 6.25 / 2 = 3.125 ml, feem. Qhov no txhais tau tias tus menyuam yuav tsum tau muab cov tshuaj hauv qab no:

5.3 ml ntawm kev ncua kev kawm ntawv nrog qhov sib xyaw ntawm 125 mg peb zaug hauv ib hnub txhua 8 teev,
6.25 ml ntawm kev ncua nrog lub zog ntawm 200 mg ob zaug ib hnub tom qab 12 teev,
Ntawm 3.125 ml ntawm ncua kev kawm ntawv nrog qhov sib zog ntawm 400 mg ob zaug ib hnub tom qab 12 teev.

Ib yam li ntawd, qhov ntau npaum li cas ntawm kev ncua yog xam rau qee kis, suav txog qhov hnyav ntawm lub cev ntawm tus menyuam thiab qhov mob ntawm nws qhov mob.

Ntxiv nrog rau txoj kev teev tshwj xeeb rau kev xam cov nyiaj ncua kev raug ncua rau qee kis tshwj xeeb, koj tuaj yeem siv cov qauv tshuaj rau cov hnub nyoog thiab lub cev hnyav. Cov qauv tshuaj zoo li cas tau qhia hauv lub rooj.

Muaj hnub nyoog menyuam	Tus me nyuam hnyav	Ncua Kev Kawm Ntawv 125 / 31.25 (noj cov koob txhaj 3 zaug ib hnub)	Raug tshem tawm 200 / 28.5 thiab 400/57 (noj cov koob txhaj 2 zaug ib hnub)
3 lub hlis - 1 xyoos	2 - 5 kg	1.5 - 2.5 ml	1.5 - 2.5 ml tshem tawm 200 mg
3 lub hlis - 1 xyoos	6 - 9 kg	5 ml	5 ml raug tshem tawm 200 mg
1 - 5 xyoos	10 - 18 kg	10 ml	5 ml raug tshem tawm 400 mg
6 - 9 xyoo	19 - 28 kg	15 ml lossis 1 ntsiav tshuaj 250 + 125 mg 3 zaug ib hnub	7.5 ml ntawm kev ncua ntawm 400 mg lossis 1 ntsiav tshuaj ntawm 500 + 125 mg 3 zaug ib hnub
10 txog 12 xyoos	29 - 39 kg	20 ml lossis 1 ntsiav tshuaj 250 + 125 mg 3 zaug ib hnub	10 ml ntawm kev ncua ntawm 400 mg lossis 1 ntsiav tshuaj ntawm 500 + 125 mg 3 zaug ib hnub

Cov lus no tuaj yeem siv tau sai sai txiav txim qhov kev ncua ntawm kev ncua ntawm ntau ntau yam rau cov menyuam yaus hnub nyoog sib txawv thiab lub cev hnyav. Txawm li cas los xij, nws raug nquahu los laij cov tshuaj noj ib lub zuj zus, vim qhov no yuav txo qhov kev phom sij ntawm kev mob tshwm sim thiab lub nra rau lub raum thiab mob siab rau tus menyuam.

Augmentin ntsiav tshuaj - cov lus qhia rau kev siv (nrog rau kev xaiv ntau thiab)

Cov ntsiav tshuaj yuav tsum tau siv nyob rau hauv ib hlis tom qab qhib cov ntawv ci pob. Yog tias Augmentin ntsiav tshuaj nyob twj ywm 30 hnub tom qab qhib pob ntawv no, lawv yuav tsum muab pov tseg thiab tsis siv.

Augmentin ntsiav tshuaj yuav tsum tau siv rau cov neeg laus thiab cov menyuam yaus hnub nyoog dhau 12 xyoos nrog lub cev qhov hnyav tsawg kawg 40 kg. Qhov kev xaiv ntawm cov ntsiav tshuaj yog txiav txim siab los ntawm qhov mob hnyav thiab tsis yog nyob ntawm lub hnub nyoog thiab lub cev qhov hnyav.

Yog li, rau cov mob me thiab mob nyhav ntawm ib qho chaw hauv ib cheeb tsam, nws raug nquahu kom noj 1 ntsiav tshuaj ntawm 250 + 125 mg 3 zaug hauv ib hnub txhua 8 teev rau 7 txog 14 hnub.

Hauv kev kis mob hnyav (suav nrog cov mob mus ntev thiab rov ua dua ntawm cov kab mob genitourinary thiab ua pa), Augmentin ntsiav tshuaj yuav tsum tau ua raws li hauv qab no:

1 ntsiav tshuaj 500 + 125 mg 3 zaug hauv ib hnub txhua 8 teev,
1 ntsiav tshuaj ntawm 875 + 125 mg 2 zaug ib hnub twg txhua 12 teev.

Qhov loj ntawm tus mob yog txiav txim siab los ntawm qhov hnyav ntawm intoxication tshwm sim: yog tias mob taub hau thiab kub yog mob pes nrab (tsis siab dua 38,5 o C), ces qhov no yog mob sib khuav lossis mob hnyav. Yog hais tias lub cev kub nce siab dua 38.5 o C, tom qab ntawv qhov no yog chav kawm hnyav.

Yog tias xav tau kev kho mob sai, koj tuaj yeem hloov kho cov ntsiav tshuaj nrog kev ncua raws li kev sib haum xeeb hauv qab no: 1 ntsiav tshuaj ntawm 875 + 125 mg yog sib npaug rau 11 ml ntawm ncua kev kawm ntawm 400/57 mg. Lwm txoj kev xaiv rau kev hloov cov ntsiav tshuaj nrog rau kev ncua tsis tuaj yeem ua tau, vim tias cov tshuaj hauv lawv yuav tsis zoo ib yam.

Cov lus qhia tshwj xeeb

Hauv cov neeg laus, kho cov tshuaj ntawm Augmentin tsis tsim nyog. Cov tib neeg muaj kab mob siab yuav tsum soj ntsuam kev ua haujlwm ntawm lub cev, xws li kev ua si ntawm AsAT, AlAT, ALP, thiab lwm yam nyob rau txhua lub sijhawm ntawm kev siv Augmentin.

Ua ntej koj pib siv Augmentin, koj yuav tsum ua kom ntseeg tau tias ib tus neeg tsis muaj kev fab tshuaj rau cov tshuaj tua kab mob ntawm penicillin thiab cephalosporin pawg. Yog tias muaj qhov ua xua tshwm sim thaum siv Augmentin, tom qab ntawd cov tshuaj yuav tsum nres tam sim ntawd thiab tsis txhob siv ntxiv lawm.

Augmentin yuav tsum tsis txhob siv rau hauv rooj plaub uas xav tias muaj mob mononucleosis.

Thaum noj Augmentin hauv kev siv tshuaj ntau kawg, tsawg kawg 2 - 2.5 litres ntawm cov kua hauv ib hnub yuav tsum tau haus kom lub teeb liab ntau ntau tsis tsim nyob rau hauv cov zis, uas tuaj yeem kos lub qhov zis thaum tso zis.

Thaum siv kev ncua, nco ntsoov txhuam koj cov hniav ob peb zaug hauv ib hnub los tiv thaiv kev qias neeg.

Hauv raum tsis ua hauj lwm nrog kev tshem tawm ntawm ntau tshaj 30 ml / min, Augmentin yuav tsum noj tshuaj ntau npaum li cas rau ib tus neeg lub hnub nyoog thiab hnyav. Yog tias creatinine tshem tawm ntawm lub raum tsis ua haujlwm tsawg dua 30 ml / min, tom qab ntawd tsuas yog siv cov Augmentin li nram no coj los ua:

Kev Ncua Quaj nrog lub siab ntawm 125 / 31.25 mg,
250 + 125 mg ntsiav tshuaj
500 + 125 mg ntsiav tshuaj
Kev daws rau kev txhaj tshuaj 500/100 thiab 1000/200.

Cov koob tshuaj ntawm cov ntaub ntawv ntawm Augmentin rau siv rau kev ua haujlwm hauv lub raum ua haujlwm nrog creatinine tshem tawm tsawg dua 30 mg / ml yog pom hauv lub rooj.

Creatinine kev tshem tawm	Ncua Sijhawm Muab Tshuaj Tawm 125 / 31.25 mg	Muab koob tshuaj ntawm ntsiav tshuaj 250 + 125 mg thiab 500 + 125 mg	Caj Ces Txhaj Tshuaj Loj	Koob tshuaj txhaj rau cov menyuam yaus
10 - 30 mg / ml	Noj 15 mg rau 1 kg ntawm lub cev hnyav 2 zaug ib hnub	1 ntsiav tshuaj 2 zaug ib hnub	Thawj zaug kev qhia 1000/200, tom qab ntawd 500/100 2 zaug ib hnub	Sau 25 mg rau 1 kg ntawm qhov hnyav 2 zaug hauv ib hnub
Tsawg tshaj li 10 mg / ml	Noj 15 mg rau 1 kg ntawm lub cev hnyav 2 zaug ib hnub	1 ntsiav tshuaj ib hnub ib zaug	Thawj cov lus qhia 1000/200, tom qab ntawd 500/100 1 zaug nyob rau ib hnub	Sau 25 mg rau 1 kg ntawm qhov hnyav 1 zaug hauv ib hnub

Kev cuam tshuam nrog lwm yam tshuaj

Nrog tib lub sijhawm siv ntawm Augmentin thiab tsis siv tshuaj tua kabmob (Warfarin, Thrombostop, thiab lwm yam), INR yuav tsum tau saib xyuas, vim nws tuaj yeem hloov pauv. Hauv qhov no, nws yog ib qho tsim nyog yuav tau kho cov tshuaj ntau ntau ntawm cov tshuaj anticoagulants rau lub sijhawm uas lawv ua ke nrog kev sib tw nrog Augmentin.

Probenecid ua rau muaj kev nce ntxiv hauv cov concentration ntawm Augmentin hauv cov ntshav. Allopurinol thaum noj Augmentin ua rau muaj kev pheej hmoo ntawm kev tsim cov tawv nqaij ua kom hnyav.

Augmentin ua rau kom muaj tshuaj lom quav ntxiv ntawm methotrexate thiab txo cov txiaj ntsig ntawm kev sib xyaw ua ke ntawm qhov ncauj. Yog li, tawm tsam cov keeb kwm yav dhau los ntawm kev siv Augmentin, yuav tsum siv lwm txoj kev tswj kom tsis txhob muaj menyuam yaus ntau ntxiv.

Cov rooj noj mov

Nyob ntawm seb qhov koob tshuaj ntawm cov tshuaj sib txuas zoo li cas, cov tshuaj tau tawm rau cov menyuam muaj hnub nyoog 12 xyoos raws li hauv qab no:

Amoxicillin thiab clavulanic acid ntau npaum	Yuav noj li cas
250mg + 125mg	1 ntsiav tshuaj peb zaug ib hnub yog tias qhov mob hnyav tau mob sib khuav lossis mob pesnrab
500mg + 125mg	1 ntsiav tshuaj txhua 8 teev, i.e. peb zaug ib hnub
875mg + 125mg	1 ntsiav tshuaj nrog kev sib nrug ntawm 12 teev, uas yog, ob zaug ib hnub

Noj ntau dhau

Yog tias cov lus pom zoo rau kev siv tsis ua raws, Augmentin hauv kev noj tshuaj ntau dhau cuam tshuam rau txoj hnyuv thiab tuaj yeem cuam tshuam cov dej-ntsev kom sib npaug hauv tus menyuam lub cev. Cov tshuaj kuj ua rau lub ntsej muag crystalluria, uas cuam tshuam loj rau kev ua haujlwm ntawm lub raum. Nrog kev noj ntau tshaj rau cov menyuam yaus lub raum tsis ua haujlwm, mob nriaj yog ua tau.

Kev cuam tshuam nrog lwm yam tshuaj

Yog tias koj muab cov tshuaj ua ke nrog cov tshuaj tso quav lossis cov tshuaj tiv thaiv kab mob, qhov no yuav ua rau muaj zog ntawm Augmentin.
Cov tshuaj tsis pom zoo kom ua ke nrog cov tshuaj tua kab mob bacteriostatic, piv txwv li, nrog tetracycline tshuaj los yog macrolides. Lawv muaj cov nyhuv tawm tsam.
Cov tshuaj tsis yog siv nrog methotrexate (nws cov tshuaj lom ntau ntxiv) lossis allopurinol (kev phom sij ntawm cov tawv nqaij ua xua nce).
Yog tias koj muab cov tshuaj tiv thaiv tsis ncaj nrog rau cov tshuaj tua kab mob no, lawv cov kev kho mob nce ntxiv.

Cov Nta Cia

Khaws hauv tsev daim ntawv tawv ntawm Augmentin qhia hauv qhov kub ntawm qhov tsis siab tshaj + 250C. Rau khaws cia ntawm cov tshuaj, qhov chaw qhuav yog qhov zoo tshaj plaws hauv kev ua kom tus menyuam yaus tsis tuaj yeem txais tshuaj. Lub txee lub neej ntawm ntsiav tshuaj 500mg + 125mg yog 3 xyoos, thiab cov tshuaj nrog rau lwm cov tshuaj yog 2 xyoos.

Feem ntau, cov niam txiv teb tau zoo rau kev siv Augmentin hauv menyuam yaus, ceeb toom tias cov tshuaj no ua sai sai thiab tua cov kab mob kis tau zoo heev. Kev txiav txim los ntawm kev xyuas, cov kev mob tshwm sim tsis tshua pom tshwm thaum noj nws. Ntawm lawv, qhov tshwm sim tsis zoo ntawm lub zom zaub mov feem ntau tau sau tseg.

Txhawm rau hloov los ua cov ntawv hnyav ntawm Augmentin, lwm tus neeg sawv cev nrog kev sib xyaw ua ke ntawm cov tshuaj yeeb dej caw tuaj yeem siv, piv txwv li:

Yuav luag tag nrho cov tshuaj no tau nthuav tawm hauv cov qauv tshuaj, tab sis qee cov kuj muaj nyob hauv kev ncua. Ntxiv rau, lwm qhov penicillin tshuaj tua kab mob los yog cephalosporin (Suprax, Amosin, Pantsef, Ecobol, Hikontsil) tuaj yeem hloov pauv rau Augmentin. Txawm li cas los xij, xws li cov kab mob analogue yuav tsum raug xaiv ua ke nrog tus kws kho mob, nrog rau tom qab kev txheeb xyuas ntawm qhov kev nkag siab ntawm tus kab mob.

Augmentin - analogues

Kev ua lag luam tshuaj muaj ntau ntawm Augmentin cov lus ua, uas tseem muaj cov tshuaj amoxicillin thiab clavulanic acid raws li cov khoom siv hauv cheeb tsam. Cov tshuaj no yog txhais ua cov lus sib hloov ntawm cov khoom nquag.

Cov tshuaj hauv qab no raug xa mus rau rau xws li Augmentin analogues ua cov khoom xyaw dhia:

Amovikomb hmoov rau kev daws rau kev txhaj tshuaj,
Amoxivan hmoov rau kev daws rau kev txhaj tshuaj,
Amoxiclav ntsiav tshuaj thiab hmoov rau kev npaj ntawm kev txhaj tshuaj thiab raug ncua rau kev tswj hwm ntawm qhov ncauj,
Amoxiclav Quiktab ntsiav tshuaj dispersible,
Amoxicillin + Clavulanic acid hmoov rau tov rau kev txhaj tshuaj,
Arlet tshuaj,
Cov ntsiav tshuaj Baktoclave,
Verklav hmoov rau tov rau kev txhaj tshuaj,
Clamosar hmoov rau kev daws rau kev txhaj tshuaj,
Lyclav hmoov rau tov rau kev txhaj tshuaj,
Medoclave ntsiav tshuaj thiab hmoov rau kev npaj rau kev ncua ntawm kev tswj hwm qhov ncauj thiab kev daws teeb meem rau kev txhaj tshuaj,
Panclave ntsiav tshuaj,
Panclav 2X ntsiav tshuaj thiab hmoov rau qhov ncauj ncua,
Ranclav ntsiav tshuaj,
Rapiclav ntsiav tshuaj
Fibell hmoov rau tov rau kev txhaj tshuaj,
Ntsiav tshuaj Flemoklav Solutab,
Foraclav hmoov rau tov rau kev txhaj tshuaj,
Ecoclave ntsiav tshuaj thiab hmoov rau kev daws qhov ncauj.

Kev txheeb xyuas txog Augmentin

Kwv yees li 80 - 85% kev tshuaj xyuas ntawm Augmentin yog qhov zoo, uas yog vim qhov ua tau ntawm cov tshuaj hauv kev kho mob rau kev kho mob rau tib neeg. Hauv kev yuav luag txhua qhov kev tshuaj xyuas, tib neeg qhia tias muaj txiaj ntsig zoo ntawm cov tshuaj, vim tias nws muaj kev kho sai rau ib tus mob kis. Txawm li cas los xij, nrog rau cov lus hais txog kev ua haujlwm ntawm Augmentin, tib neeg qhia tias muaj cov kev mob tshwm sim uas tsis zoo lossis lub siab tsis zoo. Nws yog qhov tshwm sim ntawm cov kev mob tshwm sim uas yog lub hauv paus rau cov seem 15 - 20% ntawm kev tshuaj xyuas tsis zoo sab laug txawm hais tias qhov kev ua tau zoo ntawm cov tshuaj.