Lub teeb kuaj mob insulin > Cov tshuaj insulin

Lantus yog qhov yuav npaj cov insulin-txos qis dua. Qhov nquag ua haujlwm ntawm lub lantus yog cov tshuaj insulin glargine - ib qho khoom sib piv ntawm tib neeg cov tshuaj insulin, tsis zoo rau hauv ib puag ncig nruab nrab.

Hauv Lantus, cov tshuaj yeeb yaj kiab raug tshem tawm tag vim yog qhov tshwj xeeb acidic nruab nrab, thiab nrog kev tswj hwm subcutaneous, cov kua qaub yog neutralized thiab microprecipitates raug tsim, ntawm uas insulin glargine maj mam tso tawm me me. Yog li, nyob rau hauv cov ntshav ntshav tsis muaj qhov txawv txav ntawm cov kua dej, tab sis pom qhov muaj qhov sib luag ntawm cov concentration-sijhawm nkhaus yog pom. Microprecipitate muab cov tshuaj ua nrog lub sijhawm ntev.

Pharmacological kev ua

Qhov nquag ua haujlwm ntawm lub lantus muaj qhov sib txuam rau insulin receptors zoo ib yam li kev sib raug zoo rau tib neeg cov insulin. Glargine khi rau cov tshuaj insulin receptor IGF-1 5-8 zaug muaj zog dua li tib neeg cov insulin, thiab nws cov metabolites tsis muaj zog.

Kev kho kom haum siab ntawm kev sib koom ua ke ntawm cov nquag muaj feem ntawm insulin thiab nws cov metabolites hauv cov ntshav ntawm cov neeg mob ntshav qab zib hom 1 ntshav qab zib qis qis dua qhov tsim nyog kom ntseeg tau tias ib nrab-qhov siab tshaj qhov txuas nrog IGF-1 receptors thiab txuas ntxiv ua rau cov kab mob mitogenic-proliferative catalyzed los ntawm cov receptor no.

Cov txheej txheem no ib txwm ua haujlwm los ntawm endogenous IGF-1, tab sis kev siv tshuaj tua kab mob ntawm cov tshuaj insulin uas siv hauv kev siv tshuaj insulin yog qhov qis dua qhov ntau qhov chaw muag tshuaj uas tsim nyog los ua rau lub tshuab los ntawm IGF-1.

Lub luag haujlwm tseem ceeb ntawm ib qho insulin, suav nrog glargine, yog kev cai ntawm cov piam thaj glucose (carbohydrate metabolism). Cov tshuaj insulin lantus ua kom nrawm nrawm rau cov piam thaj los ntawm adipose thiab cov leeg nqaij, vim qhov ntawd ua rau ntshav plasma cov ntshav qab zib tsawg dua. Tsis tas li, cov tshuaj no inhibits qhov ua haujlwm ntawm cov piam thaj hauv lub siab.

Cov tshuaj Insulin ua kom lub zog ntawm cov protein nyob hauv lub cev, thaum tab tom ua kom cov txheej txheem ntawm cov khoom (proteolysis) thiab lipolysis hauv adipocytes.

Cov kev tshawb fawb soj ntsuam thiab chaw muag tshuaj tau qhia tias thaum muab tshuaj rau tib leeg, qhov tshuaj tiv thaiv tib yam nkaus ntawm insulin glargine thiab tib neeg insulin yog qhov sib npaug. Qhov kev ua ntawm insulin glargine hauv lub sijhawm, zoo li lwm tus neeg sawv cev ntawm qhov koob no, nyob ntawm kev ua haujlwm ntawm lub cev thiab ntau lwm yam.

Nrog rau kev tswj hwm subcutaneous, cov tshuaj Lantus yog maj mam nqus, kom nws tuaj yeem siv ib hnub ib zaug. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias muaj cov kev paub cuam tshuam kev hloov pauv txawv hauv qhov xwm ntawm kev ua ntawm insulin lub sijhawm. Cov kev tshawb fawb pom tau tias qhov kev hloov pauv ntawm cov ntshav qab zib ua kom tsis muaj qhov sib txawv loj thaum siv insulin glargine thiab insulin NPH.

Nrog kev siv cov Lantus hauv cov menyuam yaus thiab cov hluas, kev txhim kho ntawm nocturnal hypoglycemia tau pom tsawg dua li nyob hauv pawg ntawm cov neeg mob tau txais NPH insulin.

Tsis zoo li insulin NPH, glargine vim kev nqus sai tsis ua rau lub ncov tom qab kev tswj hwm subcutaneous. Kev sib luag ntawm cov tshuaj nyob rau hauv cov ntshav ntshav yog pom rau ntawm 2 - 4 hnub ntawm kev kho mob nrog rau kev tswj hwm niaj hnub ib zaug. Ib nrab-lub neej ntawm insulin glargine thaum tswj cov tshuaj sib raug rau lub sijhawm zoo sib xws ntawm tib neeg insulin.

Nrog rau cov metabolism hauv ntawm insulin glargine, qhov tsim ntawm ob lub tebchaw nquag M1 thiab M2 tshwm sim. Kev txhaj tshuaj subantaneous ntawm Lantus muaj qhov cuam tshuam vim yog raug M1, thiab M2 thiab insulin glargine tsis raug kuaj nyob hauv feem ntau ntawm cov ncauj lus.

Qhov ua tau zoo ntawm cov tshuaj Lantus yog ib yam hauv pawg sib txawv ntawm cov neeg mob. Hauv chav kawm ntawm cov kev tshawb fawb, pab pawg tau tsim los ntawm hnub nyoog thiab poj niam txiv neej, thiab cov nyhuv ntawm cov tshuaj insulin hauv lawv yog tib yam li cov pej xeem tseem ceeb (raws li kev ua tau zoo thiab kev nyab xeeb). Hauv cov menyuam yaus thiab tub ntxhais hluas, kev tshawb fawb pharmacokinetics tsis tau ua.

Kev ntsuas rau siv

Lantus yog tsim rau kev kho mob rau cov ntshav qab zib-insulin nyob rau cov neeg laus thiab cov menyuam yaus hnub nyoog tshaj li 6 xyoo.

Cov tshuaj yog siv rau kev coj ua subcutaneous, nws yog txwv tsis pub muab tso rau hauv txoj leeg ntshav. Cov txiaj ntsig ntev ntawm cov roj lantus yog txuam nrog nws cov lus qhia rau hauv cov rog subcutaneous.

Nws yog ib qho tseem ceeb kom tsis txhob hnov qab tias nrog kev tswj hwm ntawm cov tshuaj kho mob ib txwm muaj, cov tshuaj tiv thaiv ntshav qab zib siab hnyav tuaj yeem tsim kho. Thaum siv cov tshuaj no, yuav tsum muaj ntau txoj cai:

Thaum lub sijhawm kev kho mob, koj yuav tsum ua raws li qee qhov kev ua neej thiab muab qhov hno kom raug.
Koj tuaj yeem nkag mus rau cov tshuaj hauv plab plab, ntxiv rau hauv tus ncej lossis cov leeg txhaws. Tsis muaj qhov sib txawv hauv qhov chaw kho mob nrog cov hau kev ntawm cov thawj coj.
Txhua qhov kev txhaj tshuaj yog zoo tshaj plaws nyob rau qhov chaw tshiab hauv thaj chaw pom zoo.
Koj tsis tuaj yeem yug Lantus lossis sib tov nws nrog lwm yam tshuaj.

Lantus yog qhov ua yeeb yam ntev ntev, yog li nws yuav tsum tau txhaj tshuaj ib hnub ib zaug, zoo dua rau tib lub sijhawm. Cov koob tshuaj rau txhua tus neeg tau xaiv ib tus zuj zus, nrog rau lub koob thiab lub sijhawm ntawm thawj coj.

Nws yog qhov lees txais tau los sau cov tshuaj Lantus rau cov neeg mob uas kuaj mob hom 2 mob ntshav qab zib mellitus ua ke nrog cov tshuaj tiv thaiv kab mob rau kev tswj hwm qhov ncauj.

Nws yog ib qho tseem ceeb uas yuav tau txiav txim siab hais tias cov kev ntsuas ntawm kev ua ntawm cov tshuaj no yog txawv ntawm qhov kev ntsuas ntawm lwm cov tshuaj muaj cov tshuaj insulin.

Cov neeg laus yuav tsum kho lub tshuaj, vim tias lawv tuaj yeem txo qis qhov xav tau ntawm cov tshuaj insulin vim muaj kev puas tsuaj hauv lub raum. Tsis tas li ntawd, nyob rau hauv cov neeg mob uas lub siab tsis ua haujlwm zoo, qhov xav tau ntawm insulin yuav poob qis. Qhov no yog vim qhov tseeb tias cov tshuaj insulin metabolism ua rau qeeb dua, thiab gluconeogenesis tseem txo qis.

Hloov mus rau Kab Ntsuas nrog lwm hom insulin

Yog hais tias ib tus neeg ua ntej siv tshuaj ntawm nruab nrab thiab siab ntev ntawm kev nqis tes ua, tom qab ntawd hloov mus rau Lantus, feem ntau nws yuav xav kho qhov tshuaj ntawm cov tshuaj inulin, nrog rau kev tshuaj xyuas cov kev kho dua.

Txhawm rau txo qis kev pheej hmoo ntawm cov ntshav qog ntshav thaum sawv ntxov thiab thaum tsaus ntuj, thaum hloov lub sijhawm ob lub sijhawm tswj hwm ntawm basal insulin (NPH) rau kev txhaj tshuaj ib leeg (Lantus), qhov tshuaj ntawm cov tshuaj insal basal yuav tsum tau txo 20-30% thaum thawj nees nkaum hnub ntawm kev kho mob. Thiab cov koob tshuaj ntawm cov tshuaj insulin muab txuas nrog kev noj mov yuav tsum tau nce ntxiv me ntsis. Tom qab ob mus rau peb lub lis piam, kev hloov kho tshuaj yuav tsum tau nqa tawm ntawm tus kheej rau txhua tus neeg mob.

Yog tias tus neeg mob tau txais cov tshuaj tiv thaiv rau tib neeg cov tshuaj insulin, tom qab ntawd thaum siv Lantus, lub cev tau teb rau cov tshuaj insulin hloov pauv, uas tseem yuav xav tau kev tshuaj xyuas. Nws tseem yog qhov tsim nyog thaum hloov txoj kev ua neej, hloov qhov hnyav ntawm lub cev lossis lwm yam cuam tshuam uas cuam tshuam rau kev coj ua ntawm cov tshuaj.

Cov tshuaj Lantus yuav tsum raug tswj hwm tsuas yog siv OptiPen Pro1 lossis ClickSTAR koob txhaj tshuaj. Ua ntej pib siv, koj yuav tsum ua tib zoo kawm cov lus qhia rau tus cwj mem thiab ua raws txhua qhov kev lag luam pom zoo. Qee qhov kev cai rau kev siv cov xaum xim:

Yog tias tus kov tawg, ces nws yuav tsum tau muab pov tseg thiab ib qho tshiab siv.
Yog tias tsim nyog, cov tshuaj los ntawm daim cartridge tuaj yeem raug tswj nrog cov tshuaj insulin tshwj xeeb nrog cov nplai ntawm 100 units hauv 1 ml.
Lub taub ntim yuav tsum khaws cia ntawm chav tsev qhov chaw sov li ob peb teev ua ntej muab tso rau hauv cov xaum xaum.
Koj tuaj yeem siv cov kab ntawv ntawd nkaus xwb uas qhov pom ntawm kev daws tsis tau hloov, nws cov xim thiab qhov pom, tsis muaj nag lossis daus tau tshwm sim.
Ua ntej qhia kev daws los ntawm daim cartridge, nco ntsoov tshem cov pa npuas (yuav ua li cas, nws tau sau nyob rau hauv cov lus qhia rau tus cwj mem).
Refilling cartridges yog nruj me ntsis txwv tsis pub.
Txhawm rau tiv thaiv kev raug mob los ntawm lwm yam tshuaj insulin es tsis txhob siv cov glargine, nws yog qhov yuav tsum tau kuaj xyuas cov ntawv lo ntawm txhua qhov kev txhaj tshuaj.

Sab sij huam

Feem ntau cov feem ntau, hauv cov neeg mob uas tsis nco qab zoo thaum siv cov tshuaj Lantus yog hypoglycemia. Nws muaj kev vam meej yog tias cov tshuaj tau muab tshuaj rau hauv ntau npaum li qhov tsim nyog rau tus neeg mob. Cov kev tsis zoo hauv qab no kuj tseem yuav tshwm sim rau kev qhia ntawm Lantus:

los ntawm cov kev paub ntawm cov plab hnyuv siab raum thiab lub paj hlwb - dysgeusia, kev tsis pom zoo hauv kev pom tseeb, rov ua haujlwm,
nyob rau ntawm daim tawv nqaij, nrog rau cov nqaij mos ua kom raug mob - lipohypertrophy thiab lipoatrophy,
hypoglycemia (teeb meem metabolic tsis txaus),
kev tsis haum - kev ua xua thiab liab rau ntawm daim tawv nqaij ntawm qhov chaw txhaj tshuaj, urticaria, anaphylactic shock, bronchospasm, Quincke's edema,
kev ncua ntawm sodium ions hauv lub cev, mob leeg.

Nws yuav tsum tau yug los rau hauv lub siab tias yog qhov kev mob ntshav qab zib ntau dhau los, feem ntau txoj kev pheej hmoo ntawm kev tsim teeb meem nyob rau hauv kev ua haujlwm ntawm lub paj hlwb tau siab. Ntev ntshav siab thiab ntshav qis yog qhov txaus ntshai rau tus neeg mob lub neej.

Thaum kho cov tshuaj insulin, cov tshuaj tiv thaiv tuaj yeem tsim cov tshuaj.

Hauv cov menyuam yaus thiab tub ntxhais hluas, qhov tsis tsim nyog xws li mob leeg, qhov tshwm sim tsis haum, qhov mob ntawm qhov chaw txhaj tshuaj tuaj yeem txhim kho cov tshuaj Lantus. Feem ntau, rau ob tus laus thiab menyuam yaus, kev nyab xeeb ntawm Lantus yog nyob rau tib theem.

Cov Yuav Tsum Muaj

Lantus yuav tsum tsis txhob raug rau cov neeg mob uas tsis txaus siab rau cov tshuaj nquag lossis cov khoom siv pabcuam hauv kev daws teebmeem, ntxiv rau cov neeg mob ntshav qab zib.

Hauv cov menyuam yaus, kab mob Lantus tuaj yeem raug kho yog tias lawv muaj hnub nyoog 6 xyoo thiab laus dua.

Raws li yeeb tshuaj ntawm kev xaiv rau kev kho mob ntshav qab zib ketoacidosis, cov tshuaj no tsis tau sau tseg.

Nws yog ib qho tsim nyog yuav tsum tau siv Lantus ua tib zoo siv rau hauv cov neeg mob uas muaj kev pheej hmoo ntau rau kev noj qab haus huv thaum lub sijhawm muaj ntshav qab zib tsawg, tshwj xeeb tshaj yog rau cov neeg mob nqaim ntawm lub hlwb thiab cov hlab ntsha lossis cov hlab ntsha hlwb loj loj, cov lus qhia qhia txog qhov no.

Nws yog ib qho tsim nyog yuav tsum tau ceev faj nrog cov neeg mob uas qhov tshwm sim ntawm kev mob ntshav qab zib tuaj yeem ua npog ntsej muag, piv txwv li, nrog cov leeg mob hlwb, kev puas siab puas ntsws, maj mam txhim kho hypoglycemia, thiab lub caij nyoog ntev ntawm mob ntshav qab zib mellitus. Nws tseem yog qhov yuav tsum tau ua tib zoo sau Lantus rau cov neeg laus thiab cov neeg mob uas tau hloov mus rau tib neeg cov kua dej los ntawm cov tshuaj ntawm tsiaj keeb kwm.

Thaum siv Lantus, koj yuav tsum tau ua tib zoo saib xyuas cov tshuaj hauv cov neeg uas muaj kev pheej hmoo siab ntawm kev mob ntshav qab zib siab ntau. Qhov no yuav tshwm sim thaum:

nce qhov rhiab heev ntawm cov hlwb mus rau insulin, piv txwv li, ntawm kev tshem tawm yam ua rau kev ntxhov siab,
kev tawm dag zog lub cev,
raws plab thiab ntuav
kev noj tsis txaus, nrog rau noj mov hla zaub mov,
haus cawv
kev tswj hwm ntawm qee cov tshuaj.

Hauv kev kho mob ntawm Lantus, nws zoo dua tsis koom rau hauv cov haujlwm uas xav tau kev saib xyuas, vim tias hypoglycemia (zoo li hyperglycemia) tuaj yeem ua rau txo qis ntawm qhov pom thiab pom tseeb.

Lantus thiab cev xeeb tub

Hauv cov poj niam cev xeeb tub, tsis tau tshawb nrhiav qhov kev tshawb fawb txog cov tshuaj no tau ua tiav. Cov ntaub ntawv tau tsuas yog nyob rau hauv kev tshawb fawb tom qab kev lag luam (kwv yees li 400 - 1000 tus neeg mob), thiab lawv tau qhia tias insulin glargine tsis muaj kev cuam tshuam zoo rau lub sijhawm cev xeeb tub thiab kev loj hlob ntawm tus menyuam.

Cov tsiaj sim tau pom tias insulin glargine tsis muaj kev phom sij rau lub cev xeeb tub thiab tsis ua rau muaj kev cuam tshuam txog kev muaj menyuam.

Cov poj niam cev xeeb tub Lantus tuaj yeem raug xaj los ntawm kws kho mob yog tias tsim nyog. Nws yog ib qho tseem ceeb nyob rau tib lub sijhawm los saib xyuas cov kua qab zib txhua tus thiab ua txhua yam kom muaj cov piam thaj hauv ntshav ntawm cov poj niam cev xeeb tub, nrog rau saib xyuas cov kev mob ntawm cov niam uas tseem muaj nyob thaum lub sijhawm xeeb tub. Hauv thawj peb lub hlis, xav tau cov tshuaj insulin yuav txo qis, thiab hauv kev txiav thib ob thiab thib peb, nce ntxiv. Tam sim ntawd tom qab yug tus menyuam tas, lub cev xav tau cov tshuaj no poob qis thiab ntshav qabzib tau pib.

Nrog kev lactation, kev siv ntawm Lantus tseem ua tau nyob rau hauv kev soj ntsuam ze ntawm kev ntsuas ntau npaum li cas ntawm cov tshuaj. Thaum nqus tau rau hauv lub plab zom mov, insulin glargine raug faib ua amino acids thiab tsis ua rau muaj kev phom sij rau tus menyuam los ntawm kev pub niam mis. Cov lus qhia uas glargine kis mus rau niam cov kua mis, cov lus qhia tsis muaj.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog tib lub sijhawm siv cov tshuaj Lantus nrog qee lwm yam txhais tau tias muaj kev cuam tshuam cov metabolism hauv kev txi kev noj haus, kev hloov kho tshuaj yog tsim nyog.

Cov suab thaj txo qis ntawm cov tshuaj insulin yog txhim kho los ntawm cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj, angiotensin-hloov nyhuv tshuaj tiv thaiv, disopyramides, fibrates, monoamine oxidase inhibitors, fluoxetine, pentoxifylline, salicylates, propoxyphene, sulfonamides.

Cov nyhuv ntshav hypoglycemic ntawm Lantus yog txo qis los ntawm kev nqis tes ntawm danazol, diazoxide, corticosteroids, glucagon, diuretics, estrogens thiab progestins, somatotropin, sympathomimetics, isoniazid, phenothiazine derivatives, olanzapine, protease inhibitors, clozapine, thyroid hormones.

Qee cov tshuaj, xws li clonidine, beta-blockers, lithium thiab ethanol, tuaj yeem ob leeg txhim kho thiab ua kom lub zog ntawm Lantus.

Cov lus qhia rau kev siv ua ke nrog cov tshuaj no nrog pentamidine qhia tau tias hypoglycemia yuav tshwm sim ua ntej, uas tom qab ntawd dhau los ua hyperglycemia.

Noj ntau dhau

Kev noj tshuaj ntau dhau ntawm cov yeeb yaj kiab Lantus tuaj yeem ua rau mob hnyav, ua kom ntev thiab mob ntshav qab zib tsawg, uas yog qhov txaus ntshai rau kev noj qab haus huv thiab lub neej ntawm tus neeg mob. Yog hais tias kev noj haus ntau dhau tsis zoo qhia, nws tuaj yeem nres los ntawm kev siv carbohydrates.

Thaum muaj kev txhim kho tsis tu ncua ntawm hypoglycemia, tus neeg mob yuav tsum hloov nws txoj kev ua neej thiab kho qhov koob tshuaj uas tau siv rau kev siv.

Yog hais tias hypoglycemia manifests nws tus kheej kom meej meej heev, nrog rau kev mob nriaj nrog, mob hlwb hloov pauv, ces glucagon yuav tsum tau txhaj tshuaj subcutaneously lossis intramuscularly lossis txhaj tshuaj rau ntawm cov ntshav khov kho. Los ntawm txoj kev, tus mob muaj qhov tshwm sim hnyav tshaj plaws, thiab cov tsos mob ntawm tus mob hypoglycemic tsis meej pem, thiab qhov no yog nws, koj yuav tsum paub.

Nws yuav tsum nco ntsoov tias cov tshuaj Lantus muaj qhov cuam tshuam ntev, yog li txawm tias tus neeg mob tus mob tau zoo dua, koj yuav tsum tau noj cov zaub mov ntxiv mus ntev thiab saib xyuas qhov mob ntawm lub cev.

Cia rau cov neeg mob

Txee lub neej ntawm Lantus yog 3 xyoos, lub sijhawm no nws haum rau kev siv, kev tswj hwm kub yuav tsum tswj tsis pub dhau 2 - 8 degrees Celsius. Nws yog txwv tsis pub khov rau cov tshuaj. Tom qab qhib lub laub yuav tsum khaws cia ntawm qhov kub li 15 - 25 degrees. Txee lub neej ntawm kev qhib tshuaj tsis yog ntau dua 1 hlis.

Hauv 1 ml ntawm Lantus tov muaj:

3.6378 mg ntawm cov tshuaj insulin glargine (qhov no yog sib npaug nrog 100 units ntawm glargine),
Cov khoom xyaw pabcuam.

Ib daim cartridge nrog cov tshuaj muaj 300 tawm ntawm insulin glargine thiab tshuaj ntxiv.

Cov lus qhia rau kev siv

Ua cov txheej txheem ib hnub ib zaug tib lub sijhawm. Kev txhaj tshuaj rau hauv qhov ncauj kom zoo yuav tsum nruj me ntsis. Txhawm rau kom tsis txhob lipodystrophy, hloov thaj chaw txhaj tshuaj.

Nws tsis pom zoo kom dilute los yog sib xyaw Lantus nrog lwm cov tshuaj insulin. Qhov no tuaj yeem ua rau muaj kev hloov pauv hauv cov chaw muag tshuaj ntawm glargine.

Kev xaiv koob tshuaj yog qhov xav tau thaum hloov qhov hnyav ntawm tus neeg mob lossis nws txoj kev ua neej. Tsis tas li, qhov ntau npaum li cas ntawm cov tshuaj yog nyob ntawm lub sijhawm ntawm nws txoj kev tswj hwm.

Sab sij huam

Cov kev mob tshwm sim tsis zoo ntawm kev noj cov tshuaj yog hypoglycemia. Nws ua rau qhov tseem ceeb tshaj ntawm cov koob tshuaj ntawm cov tshuaj kwv yees rau cov kev xav tau ntawm tus mob ntshav qab zib.Lub hauv paus mob tshwm sim ua ntej los ntawm cov tsos mob xws li tachycardia, tawm hws ntau dhau, kev tshaib plab, poob siab, txob taus, blanching ntawm daim tawv nqaij. Kev mob ntshav qab zib yog nws tus kheej los ntawm cov tsos mob hauv qab no:

teeb meem tsis pom kev
cramps
qaug zog thiab qaug zog,
mob taub hau
hnov li cas txo nyob rau hauv concentration,
bouts ntawm xeev siab thiab ntuav.

Lub caij nyoog ntev thiab nquag tawm tsam cov ntshav qog ntshav qab zib txhawb kev puas tsuaj rau cov hlab ntshav ntawm lub paj hlwb. Qee zaum nws yuav ua rau neeg tuag taus.

Ib qho tsis haum rau Insulin Lantus yog kev fab tshuaj. Nws yog tsiag ntawv los ntawm kab mob edema, tawv nqaij ua pob, voos ncig hypotension, lossis bronchospasm. Qee qhov xwm txheej, kev tiv thaiv insulin tuaj vim qhov tshwm sim ntawm cov tshuaj tiv thaiv tsim nyog hauv tus neeg mob lub cev.

Lwm yam kev phiv hais suav nrog saj cuam tshuam, tsis nco qab noj qab haus huv retinopathy, myalgia, lipoatrophy, thiab lipodystrophy. Edema, mob, liab thiab khaus tshwm sim ntawm thaj chaw txhaj tshuaj. Tom qab lub sijhawm luv luv, cov phiajcim no ploj ntawm lawv tus kheej.

Cev xeeb tub thiab lactation

Cov neeg mob yuav tsum qhia lawv tus kws kho mob txog kev xeeb tub tam sim no lossis npaj yuav muaj lub zog.

Tsis muaj ib qho kev sim kho mob sib kis ntawm kev siv tshuaj insulin glargine rau cov poj niam cev xeeb tub.

Ntau qhov kev soj ntsuam (ntau tshaj 1000 qhov tshwm sim ntawm cev xeeb tub hauv kev rov ua dua tshiab thiab kev cia siab yav tom ntej) nrog kev tshaj tawm tom qab kev siv tshuaj tua kab mob insulin glargine tau qhia tias nws tsis muaj teebmeem tshwj xeeb rau ntawm chav kawm thiab cov txiaj ntsig ntawm cev xeeb tub lossis ntawm kev mob ntawm menyuam, lossis kev noj qab haus huv ntawm tus menyuam mos.

Tsis tas li ntawd, txhawm rau txheeb xyuas kev nyab xeeb ntawm insulin glargine thiab insulin-isophan siv rau cov poj niam cev xeeb tub nrog tus mob ntshav qab zib yav dhau los los yog mob ntshav qab zib hauv lub cev, cov meta-tsom xam ntawm yim soj ntsuam kev soj ntsuam tau ua, nrog rau cov poj niam uas siv insulin glargine thaum cev xeeb tub (n = 331) thiab cov tshuaj insulin isophane (n = 371).

Qhov tsom xam no tsis qhia txog qhov sib txawv txog kev nyab xeeb ntawm leej niam lossis kev noj qab haus huv tshiab thaum siv tshuaj insulin glargine thiab insulin-isophan thaum cev xeeb tub.

Hauv cov kev tshawb fawb tsiaj, tsis muaj cov ntaub ntawv ncaj qha lossis tsis ncaj rau ntawm cov embryotoxic lossis fetotoxic cov teebmeem ntawm insulin glargine.

Rau cov neeg mob uas muaj mob ntshav qab zib ua ntej los yog muaj lub cev ua rau mob ntshav qab zib, nws yog ib qho tseem ceeb kom muaj kev cai tsim nyog ntawm cov khoom noj hauv lub cev thoob plaws lub cev xeeb tub kom tiv thaiv qhov tshwm sim uas tsis xav tau qhov cuam tshuam nrog hyperglycemia.

Cov tshuaj Lantus® SoloStar ® tuaj yeem siv thaum cev xeeb tub rau kev kuaj mob.

Qhov kev xav tau rau insulin tuaj yeem txo qis hauv thawj peb lub hlis thaum cev xeeb tub thiab, feem ntau, nce ntxiv thaum txiav thib ob thiab peb feem plaub.

Tam sim ntawd tom qab yug los, xav tau cov insulin tsawg zuj zus (qhov kev pheej hmoo ntawm cov ntshav qog ntshav nce siab). Nyob rau cov xwm txheej no, kev saib xyuas kev saib xyuas ntawm cov ntshav qabzib hauv cov ntshav yog qhov tseem ceeb.

Cov neeg mob lub cev thaum lactation yuav tau kho cov tshuaj ntau dua ntawm cov tshuaj insulin thiab kev noj haus.

Hauv cov kev tshawb fawb tsiaj, tsis muaj cov ntaub ntawv ncaj qha lossis tsis ncaj rau ntawm cov embryotoxic lossis fetotoxic cov teebmeem ntawm insulin glargine.

Txog tam sim no, tsis muaj txheeb cais hais txog kev siv cov tshuaj thaum cev xeeb tub. Muaj pov thawj ntawm kev siv Lantus hauv 100 tus poj niam cev xeeb tub muaj ntshav qab zib. Cov chav kawm thiab kev tshwm sim ntawm cev xeeb tub hauv cov neeg mob no tsis txawv ntawm cov poj niam cev xeeb tub uas muaj ntshav qab zib uas tau txais lwm yam tshuaj insulin.

Kev teem caij ntawm Lantus hauv cov poj niam cev xeeb tub yuav tsum tau ua nrog ceev faj. Rau cov neeg mob uas muaj kab mob ntshav qab zib yav dhau los los yog mob ntshav qab zib hauv lub cev, nws yog ib qho tseem ceeb kom muaj kev cai tsim nyog ntawm cov khoom noj hauv lub cev thoob plaws lub cev xeeb tub.

Qhov kev xav tau rau insulin tuaj yeem txo qis hauv thawj peb lub hlis thaum cev xeeb tub thiab nce ntxiv thaum lub sijhawm thib ob thiab thib peb. Tam sim ntawd tom qab yug los, xav tau cov insulin tsawg zuj zus (qhov kev pheej hmoo ntawm cov ntshav qog ntshav nce siab).

Nyob rau cov xwm txheej no, yuav tsum tau saib xyuas kev ntshav qabzib kom zoo.

Hauv cov pojniam muaj menyuam, kev txhaj tshuaj thiab noj zaub mov kom haum.

Cov txiaj ntsig tsis zoo ntawm cov tshuaj hauv lub cev ntawm cov poj niam cev xeeb tub thiab tus me nyuam hauv plab tsis tau lees paub los ntawm kev tshawb fawb soj ntsuam. Txawm li cas los xij, cov poj niam lub sijhawm nyob rau lub sijhawm muaj menyuam yaus yuav tsum siv cov tshuaj nrog kev ceev faj, soj ntsuam nruj kev noj tshuaj uas tus kws kho mob tuaj koom.

Thaum noj cov tshuaj no, cov poj niam cev xeeb tub yuav tsum tau kuaj ntshav tas li kom tswj hwm cov ntshav qab zib hauv lub cev. Thawj 3 lub hlis uas cev xeeb tub, lub cev xav tau cov tshuaj insulin tuaj yeem txo qis, tab sis nyob rau lub sijhawm thib 2 thiab 3 nws tuaj yeem nce ntxiv. Tom qab yug tus me nyuam, xav tau cov tshuaj dua ib zaug tsawg zuj zus, uas cuam tshuam nrog kev hloov hauv keeb kwm yav dhau los.

Cev xeeb tub

Cev xeeb tub tsuas yog thaum tsim nyog nkaus xwb. Nws yog ib qho tseem ceeb uas yuav tsum saib xyuas cov qib ntawm cov piam thaj hauv cov ntshav thiab saib xyuas qhov xwm txheej ntawm tus poj niam cev xeeb tub. Hauv thawj peb lub hlis, lub cev xav tau cov tshuaj insulin tsawg dua, thiab hauv rau lub hlis tom ntej no nws nce. Tam sim ntawd tom qab xa khoom tas, qhov xav tau rau cov tshuaj no poob qis zuj zus. Muaj kev pheej hmoo ntawm lub qog ntshav qab zib.

Nrog rau lactation, noj cov tshuaj yog ua tau, tab sis nyob rau hauv kev soj ntsuam tas li ntawm kev ntau npaum. Glargin yog nqus hauv cov hnyuv thiab tawg rau hauv cov amino acids. Nws tsis muaj teebmeem dabtsi rau tus menyuam thaum pub niam mis.

Hloov mus rau Lantus los ntawm lwm hom insulin

Yog tias tus neeg mob yav dhau los siv tshuaj ntawm qhov siab thiab nruab nrab ntawm kev nqis tes ua, tom qab ntawd hloov mus rau Lantus, kev kho qhov tshuaj ntawm cov tshuaj insulin tseem ceeb yog qhov tsim nyog. Yuav tsum tau tshuaj xyuas kom yooj yim.

Thaum ob-lub sij hawm txhaj tshuaj ntawm basal insulin (NPH) raug hloov pauv mus rau kev txhaj tshuaj ib zaug ntawm Lantus, qhov koob tshuaj ntawm thawj zaug poob qis txog 20-30%. Qhov no yog ua thaum thawj 20 hnub ntawm kev kho. Qhov no yuav pab tiv thaiv kom tsis txhob muaj ntshav qab zib thaum hmo ntuj thiab sawv ntxov. Hauv qhov no, lub koob tshuaj tau muab ua ntej noj mov tau nce siab. Tom qab 2-3 lub lis piam, kho cov nqi ntawm cov tshuaj yog nqa tawm ntawm tus kheej rau txhua tus neeg mob.

Hauv lub cev qee cov neeg mob, cov tshuaj tiv thaiv rau tib neeg cov insulin yog tsim tawm. Hauv qhov no, lub cev tiv thaiv kab mob rau Lantus kev txhaj tshuaj hloov pauv. Nws kuj tseem yuav tsum tau rov tshuaj dua.

Txee lub neej thiab analogues

Khaws cov tshuaj rau hauv qhov chaw tiv thaiv los ntawm tshav ntuj. Qhov ntsuas kub zoo rau kev tswj hwm yog +2 ... +8 ° C. Cia kom khov yog qhov tsis lees txais. Nws tseem yog ib qho tseem ceeb kom tsis txhob muaj kev sib cuag nrog lub thawv nrog kev daws nrog cov zaub mov khov thiab lub tub yees txias. Tom qab rub tawm cov cwj mem syringe, nws tuaj yeem khaws cia rau 4 lub lis piam ntawm qhov kub siab txog +25 ° C.

Cov tshuaj tiv thaiv tseem ceeb ntawm cov tshuaj yog Insulin Levemir. Lub chaw tsim khoom yog Novo Nordisk. Nws tseem ua tau zoo rau cov ntshav qab zib.

Insulin Lantus yog qhov tsim nyog rau yuav luag txhua pawg neeg mob. Cov tshuaj luam tawm cov theem zoo ntawm lub cev ntawm insulin yav dhau los thiab muaj kev ua haujlwm ruaj khov.

Dab tsi yog nws muaj

Cov tshuaj tseem ceeb uas muaj cov nyhuv pharmacological ntawm cov tshuaj yog insulin glargine. Hauv 1 ml ntawm Lantus Solostar muaj txog 3.6 mg ntawm cov tshuaj yeeb tshuaj no - qhov siab no yog sib npaug rau 100 IU ntawm tib neeg cov tshuaj insulin.

Cov lus sib xyaw ua ke nrog tus naj npawb ntawm cov koom haum pabcuam, lub hom phiaj uas yog txhawm rau kom muaj cov Solostar kom tsawg, txo tus nqi ntawm qhov tsis pom kev tawm ntawm lub cev. Cov no suav nrog cov tshuaj:

Zinc chloride.
M-cresol.
Cov sodium hydroxide.
Glycerol.
Hydrochloric acid.
Dej rau kev txhaj tshuaj.

Lantus Solostar muaj nyob rau hauv daim ntawv ntawm cov xaum xaum uas yuav siv tau yam tsis muaj kev npaj tshwj xeeb. Txhua tus cwj mem muaj qee cov koob tshuaj ntawm cov tshuaj nquag, thaum lawv xaus, lub cuab yeej tsuas yog muab pov tseg thiab yuav ib qho tshiab. Qhov kev xaiv zoo tshaj plaws rau cov ntshav qab zib yog cov tshuaj uas muaj nyob hauv Opti-Click system: nws tuaj yeem siv ntau zaus - yog tias cov tshuaj insulin hauv daim laub ntim tag, ces nws tsuas yog hloov.

Muaj lwm yam tshuaj zoo ib yam - insulin Tujeo Solostar. Nws muaj ntau dua glargine, hauv 1 ml nws cov ntsiab lus nce mus txog 10.9 mg, uas sib npaug 300 PIECES ntawm tib neeg cov tshuaj insulin. Qhov sib txawv tseem ceeb ntawm cov tshuaj no thiab Lantus yog tias, hauv qhov sib piv nrog tus thib ob, nws siv sijhawm ntev npaum li cas - txog 24 teev.

Ntawm lwm cov Lantus hloov chaw, Humalog thiab Biosulin feem ntau siv. Thawj qhov yog sawv cev los ntawm cov tshuaj muaj zog insulin lispro hauv qhov nyiaj ntawm 100 IU ib milliliter. Qhov thib ob yog tib neeg kev tsim kho tshuab hauv tib qho kev xav. Ntawm txhua qhov sib txawv, qhov tseem ceeb tshaj plaws yog cov tshuaj saum toj no luv-luv, yog li lawv yuav tsum tau siv ntau zaus hauv ib hnub.

Ib qho ntawm cov yeeb yaj kiab ntawm Solostar Humalog.

Thaum yuav siv cov tshuaj

Ib cov tshuaj yog siv rau cov ntshav qab zib, uas yuav tsum tau kho nrog insulin. Ntau zaus nws yog ntshav qab zib hom 1. Qhov tshuaj hormone no tuaj yeem kho rau txhua tus neeg mob uas muaj hnub nyoog 6 xyoo.

Kev siv tshuaj insulin ntev ntev yog qhov tsim nyog los tswj lub cev ceev ceev hauv cov ntshav cov neeg mob cov ntshav. Tus neeg noj qab haus huv hauv cov hlab ntshav yeej ib txwm muaj qee qhov ntawm no, xws li cov ntsiab lus hauv cov ntshav yog hu ua theem pib. Hauv cov neeg mob uas muaj ntshav qab zib mellitus nyob rau hauv rooj plaub ntawm pancreatic kawg, xav tau cov tshuaj insulin, uas yuav tsum tau txhaj tshuaj tsis tu ncua.

Lwm qhov kev xaiv rau kev tso tawm cov tshuaj hormone hauv ntshav tau hu ua bolus. Nws cuam tshuam nrog kev noj mov - hauv kev teb rau kev nce siab hauv cov ntshav qab zib, qee qhov ntshav ntawm insulin raug tso tawm kom sai glycemia li qub. Hauv cov ntshav qab zib mellitus, insulins luv luv tau siv rau qhov no. Hauv qhov no, tus neeg mob yuav tsum txhaj nws tus kheej nrog rab koob txhaj tshuaj txhua lub sijhawm tom qab noj mov, nws muaj cov khoom tsim nyog ntawm cov tshuaj hormones.

Hauv cov tsev muag tshuaj, coob tus muab tshuaj sib txawv rau kev kho mob ntshav qab zib tau muag. Yog tias tus neeg mob xav tau siv lub cev ntev ua cov tshuaj hormones, tom qab ntawd dab tsi yog qhov zoo siv - Lantus lossis Levemir? Ntau txoj hauv kev, cov tshuaj no zoo sib xws - ob qho tib si yog qhov pib, yog qhov ua kwv yees thiab ruaj khov nyob rau hauv kev siv.

Peb yuav xyuas seb cov tshuaj hormones no txawv li cas. Nws ntseeg tias Levemir muaj lub neej ua haujlwm ntev dua li Lantus Solostar - txog 6 lub lim tiam tiv thaiv ib hlis. Yog li no, Levemir pom tau tias yooj yim dua rau kis uas koj xav tau nkag rau qhov qis ntawm cov tshuaj, piv txwv li, ua raws li cov zaub mov uas tsis muaj cov carb qis.

Cov kws txawj hais tias Lantus Solostar yuav ua rau muaj kev pheej hmoo mob qog noj ntshav, tab sis tsis muaj ntaub ntawv txaus ntseeg ntawm qhov no tseem.

Tsis txhob siv cov tshuaj uas tas sij hawm!

Yuav thov lub cuab yeej li cas

Peb yuav txheeb xyuas seb yuav siv Lantus li cas - cov lus qhia rau kev siv hais tias nws yuav tsum tau txhaj tshuaj rau hauv cov ntaub so ntswg ntawm lub plab phab ntsa sab xub ntiag, thiab nws tsis tuaj yeem siv tshuaj ntxau. Qhov qauv ntawm cov tshuaj saib xyuas yeeb tshuaj no yuav ua rau txo qis cov ntshav qabzib hauv lub ntsej muag thiab kev txhim kho ntawm lub ntsej muag hypoglycemic.

Ntxiv nrog rau fiber ntau ntawm lub plab, muaj lwm qhov chaw rau qhov kev qhia tau ntawm Lantus - cov pob txha hauv plab, cov leeg nqaij deltoid. Qhov sib txawv hauv cov nyhuv hauv cov xwm txheej no tsis txaus ntseeg lossis tsis tuaj kiag li. Qhov tshuaj tsis tuaj yeem ua ke ua ke nrog lwm cov tshuaj insulin, nws tsis tuaj yeem xeb ua ntej siv, vim qhov no txo nws cov hauj lwm zoo. Yog tias sib xyaw nrog lwm cov tshuaj pharmacological, dej nag yog tau.

Txhawm rau kom ua tau zoo kho mob, Lantus yuav tsum tau siv txuas ntxiv, txhua txhua hnub nyob rau tib lub sijhawm.

Yuav siv hom tshuaj insulin li cas rau cov ntshav qab zib, kws kho mob endocrinologist yuav qhia koj. Muaj qee kis, kev siv yeeb-tshuaj luv luv tuaj yeem muaj peev xwm kis nrog qee zaum; qee zaum yuav tsum tau muab ob qho tshuaj insulins luv thiab ntev ntev. Ib qho piv txwv ntawm kev sib koom ua ke no yog kev sib koom ua ke ntawm Lantus thiab Apidra, lossis kev sib txuam xws li Lantus thiab Novorapid.

Hauv cov xwm txheej ntawd thaum, rau qee qhov laj thawj, nws yuav tsum hloov cov tshuaj Lantus Solostar hloov mus rau lwm qhov (piv txwv, rau Tujeo), qee cov cai yuav tsum tau ua raws. Qhov tseem ceeb tshaj plaws, kev hloov pauv yuav tsum tsis txhob muaj kev nyuaj siab loj rau lub cev, yog li koj tsis tuaj yeem txo qis dua ntawm cov tshuaj raws li cov lej ntawm qhov kev txiav txim. Ntawm qhov tsis sib xws, hauv thawj hnub ntawm kev tswj hwm, kev nce ntxiv ntawm cov tshuaj insulin yog qhov ua tau kom thiaj li yuav zam tau hyperglycemia. Thaum txhua lub cev hloov mus rau txoj kev siv tshuaj tshiab zoo tshaj plaws, koj tuaj yeem txo qhov koob tshuaj rau tus nqi ib txwm. Txhua yam kev hloov pauv hauv txoj kev kho, tshwj xeeb yog cov cuam tshuam nrog kev hloov cov tshuaj nrog cov tshuaj tiv thaiv kab mob analogues, yuav tsum pom zoo nrog cov kws kho mob koom nrog, uas paub tias ib hom tshuaj txawv ntawm lwm thiab qhov twg zoo dua.

Yuav xaiv cov koob tshuaj basal hormone li cas

Nws yog qhov tseeb tshaj plaws los sab laj nrog tus kws kho mob endocrinologist uas tuaj yeem tawm tswv yim txog kev yuav txhaj Lantus insulin li cas; cov lus qhia rau kev siv cov cuab yeej no yuav tsis muab cov lus teb rau txhua lo lus nug. Ua ntej qhia cov tshuaj, cov neeg mob yuav tsum tau laij qhov koob tshuaj uas yuav tsum tau ua. Cov koob tshuaj ntawm cov tshuaj muab nyob ntawm ntau yam: tus nqi ntawm cov carbohydrates noj, lub cev nyhav, cov yam ntxwv ntawm lub cev. Txog kev suav, koj xav tau kev zoo siab rau tus kheej.

Lub ntsuas ntshav ntawm tus kheej yuav tsum nyob hauv txhua tsev neeg!

Ua ntej, koj yuav tsum xam lub sij hawm yav tsaus ntuj. Tus neeg mob yuav tsum, li niaj zaus noj zaub mov rau noj su thiab tsis txhob noj ntau rau hnub ntawd, thiab tsis txhob txhaj Lantus Solostar lossis lwm yam tshuaj noj. Pib txij rau rau thaum yav tsaus ntuj, ntsuas koj cov ntshav qab zib txhua teev thiab ib nrab. Yog tias muaj cov cim suab thaj nce ntxiv hauv ntshav qab zib, tom qab ntawd txhaj cov tshuaj insulin me me rau cov kab mob glycemia ib txwm muaj.

Thaum 22:00 koj yuav tsum tso tus txheej txheem tshuaj insulin rau lub caij nyoog ntev. Yog tias koj siv Tujeo Solostar, hauv cov khoom ua kom nquag muaj 300 PIECES, qhov xav kom pib ntawm yuav yog 6 PIECES. Tom qab ob xuab moos, cov ntshav qabzib tau ntsuas dua. Cov neeg mob yuav tsum tau sau cia rau hauv qhov chaw kho mob txhua qhov tau txais cov ntaub ntawv ntsuas, nrog rau cov koob tshuaj ntawm cov tshuaj insulin txhaj, lub sijhawm ntawm kev sim thiab kev tswj hwm tshuaj. Txhawm rau tiv thaiv kev txhim kho ntshav qab zib, nws pom zoo kom koj ib txwm muaj ob peb lub qab zib, kua txiv qab zib lossis lwm yam khoom noj muaj piam thaj nrog koj.

Lub hauv paus insulin peaks thaum hmo ntuj, feem ntau nyob hauv thaj tsam li 2 txog 4 teev. Nyob rau tib lub sijhawm, koj yuav tsum ntsuas ntsuas ntshav qab zib ib zaug ib teev. Qhov no yuav ua rau nws muaj peev xwm txiav txim siab seb yuav ua li cas muaj ntau qhov kev txiav txim siab ntawm kev siv tshuaj yuav tsum tau noj nyob rau yav tsaus ntuj txhawm rau kom muaj txiaj ntsig cov ntshav qab zib kom tsawg dua, tab sis tsis ua tiav ntshav qab zib thaum hmo ntuj.

Tib txoj kev txiav txim siab muab ntau npaum li cas ntawm cov tshuaj insulin glargine Lantus thaum sawv ntxov. Txawm li cas los xij, nws tsim nyog pib nrog lub ntsiab txhais ntawm yav tsaus ntuj tshuaj, tom qab ntawd los hloov cov tshuaj txhua hnub.

Koob tshuaj hloov kho

Qee qhov xwm txheej, koj yuav tsum hloov pauv cov tshuaj insulin uas tswj hwm los ntawm Solostar. Muaj ntau ntau cov laj thawj uas vim li cas qhov xav tau ntawm cov tshuaj hormones tuaj yeem nce lossis tsawg zuj zus:

Yog tias tus neeg mob haus dej cawv.
Txoj kev ntxhov siab.
Cov yuam kev ntawm cov khoom noj, kev siv cov khoom uas muaj suab thaj.
Ntau yam kab mob ntawm txoj hnyuv, uas tuaj yeem ua ke nrog zawv plab thiab ntuav.
Siv cov tshuaj.
Lub xub ntiag ntawm endocrine pathologies, piv txwv li, hypo- lossis hyperthyroidism.
Cev xeeb tub, tshwj xeeb yog cov menyuam yuav tsum loj.

Nyob rau hauv muaj somatic pathologies, ua tib zoo mloog yuav tsum tau them nyiaj rau kev hloov pauv cov tshuaj ntawm lub cev. Feem ntau xav tau cov tshuaj nce ntxiv, yog li cov neeg mob yuav tsum nquag noj qee cov khoom noj carbohydrates kom tsis txhob muaj tsos mob ntawm kev mob ntshav qab zib thiab lwm yam teeb meem.

Tsis txhob tsis quav ntsej txog kev noj qab haus huv, kom tsis txhob muaj mob rau lub cev!

Kev kho mob ntshav qab zib yuav tsum muaj lub luag haujlwm tseem ceeb los ntawm tus neeg mob txhawm rau txo qis txhua qhov tshwm sim tsis zoo uas cuam tshuam nrog tus kabmob thiab txo cov kev pheej hmoo ntawm cov teeb meem. Ntxiv rau kev siv yeeb tshuaj, kev nqis tes ua uas tau ua txhawm rau txo qis hauv glycemia, nws yog ib qho tseem ceeb kom ua raws li kev noj qab haus huv, ua raws kev noj haus. Nws tseem yuav pab tau nyeem cov lus qhia rau siv rau Lantus Solostar lossis lwm yam kev siv. Paub txog txoj cai tswj hwm kev siv tshuaj, koj tuaj yeem ua tiav lawv txoj kev ua tau zoo tshaj plaws.

Ntev ntshav Insulin - Nta ntawm Kev Kho Mob Ntshav Qab Zib

Nrog rau tus kab mob, ntshav qab zib yuav tsum tau muaj kev txhawb nqa insulin. Cov tshuaj insulin luv thiab insulin ntev ntev raug siv los kho tus mob. Qhov zoo ntawm lub neej ntawm cov ntshav qab zib feem ntau nyob ntawm kev ua raws li tag nrho cov tshuaj kho mob.

Yuav tsum siv cov insulin txuas mus tau sai thaum yoo cov ntshav cov piam thaj kom yuav tsum hloov kho. Cov insulins uas siv tau ntev tshaj plaws rau hnub no yog Levemir thiab Lantus, uas tus neeg mob yuav tsum tau noj ib zaug txhua 12 lossis 24 teev.

Cov insulin ntev ntev muaj qhov cuab yeej zoo, nws muaj peev xwm ntsi xws li lub cev ntuj tsim uas tsim los ntawm cov hlwb ntawm cov txiav. Tib lub sijhawm, nws yog maj rau ntawm cov hlwb zoo li ntawd, txhawb lawv txoj kev zoo rov los, uas yav tom ntej tso cai tsis kam hloov kho insulin.

Kev hno cov tshuaj insulin ntev ntev yuav tsum tau muab rau cov neeg mob uas muaj qib siab qab zib thaum nruab hnub, tab sis nws yuav tsum xyuas kom tus neeg mob noj zaub mov tsis pub dhau 5 teev ua ntej yuav mus pw. Tsis tas li, cov insulin ntev yog tsim rau cov tsos mob ntawm "thaum sawv ntxov kaj ntug", nyob rau hauv rooj plaub thaum lub siab pib pib thaum hmo ntuj ua ntej tus neeg mob sawv, ua kom cov insulin tsis muaj teebmeem.

Yog hais tias luv luv insulin xav tau txhaj thaum nruab hnub kom txo tau cov ntshav qabzib nrog cov zaub mov, tom qab ntawd ntev insulin tuaj yeem tiv thaiv insulin keeb kwm yav dhau los, ua qhov kev tiv thaiv zoo tshaj plaws ntawm ketoacidosis, nws kuj pab rov qab rau pancreatic beta hlwb.

Kev hno ntshav ntawm cov tshuaj insulin ntev tsim nyog tau txais kev mloog rau qhov lawv pab ua rau tus neeg mob tus kheej ib txwm muaj thiab xyuas kom meej tias cov ntshav qab zib hom 2 tsis dhau rau thawj hom kab mob.

Qhov tseeb muab xam ntawm cov koob tshuaj ntawm cov insulin ntev thaum hmo ntuj

Txhawm rau kom lub neej tsis muaj sia nyob, tus neeg mob yuav tsum tau kawm kom paub tseeb ntsuas qhov ntau thiab tsawg ntawm Lantus, Protafan lossis Levemir thaum hmo ntuj, kom cov qib nrawm nrawm nrog rau ntawm 4.6 ± 0.6 mmol / l.

Ua li no, nyob hauv lub limtiam koj yuav tsum ntsuas qib suab thaj thaum hmo ntuj thiab sawv ntxov thaum lub plab khoob. Tom qab ntawd koj yuav tsum xam qhov txiaj ntsig ntawm qab zib thaum sawv ntxov tshaj tawm nag hmo tus nqi thaum hmo ntuj thiab suav qhov nce qhov nce, qhov no yuav muab qhov ntsuas ntawm qhov tsawg kawg yuav tsum tau noj.

Piv txwv li, yog tias qhov nce qib ntawm thaj suab thaj tsawg tshaj plaws yog 4.0 mmol / l, tom qab ntawd 1 ntu ntawm cov tshuaj insulin ntev tuaj yeem txo qhov ntsuas no los ntawm 2.2 mmol / l hauv ib tus neeg hnyav 64 kg. Yog tias koj qhov hnyav hnyav 80 kg, tom qab ntawd peb siv cov qauv hauv qab no: 2.2 mmol / L * 64 kg / 80 kg = 1.76 mmol / L.

Cov koob tshuaj ntawm cov tshuaj insulin rau ib tus neeg uas hnyav 80 kg yuav tsum yog 1.13 units, tus lej no yog muab kwv yees mus rau lub quarter ze thiab peb tau txais 1.25E.

Nws yuav tsum raug sau tseg tias Lantus tsis tuaj yeem raug diluted, yog li nws yuav tsum tau txhaj nrog 1ED lossis 1,5ED, tab sis Levemir tuaj yeem raug txhaws thiab txhaj nrog qhov yuav tsum muaj tus nqi. Hauv ob peb hnub tom qab no, koj yuav tsum tau soj ntsuam seb cov piam thaj sai npaum li cas thiab yuav ua rau ntau ntxiv lossis txo cov tshuaj.

Nws yog xaiv qhov raug thiab raug yog tias, hauv ib lub lis piam, cov piam thaj sai dua tsis tshaj 0.6 mmol / l, yog tias tus nqi ntau dua, ces sim nce qhov ntau npaum ntawm 0.25 units txhua peb hnub.

Glargin thiab lwm yam tshuaj

Kev sib xyaw nrog lwm cov tshuaj cuam tshuam rau cov txheej txheem metabolic txuam nrog cov piam thaj:

Qee cov tshuaj txhim kho cov nyhuv ntawm Lantus. Cov no suav nrog sulfonamides, salicylates, tshuaj noj ntawm qhov ncauj-txo qhov ncauj, ACE thiab MAO inhibitors, thiab lwm yam.
Diuretics, sympathomimetics, protease inhibitors, ib leeg tiv thaiv kab mob, cov tshuaj hormones - poj niam, cov thyroid, thiab lwm yam tsis muaj zog cov kev cuam tshuam ntawm insulin glargine.
Kev nqus cov roj ntsha lithium, kev tiv thaiv beta-blockers lossis kev haus cawv ua rau muaj qhov tsis meej xwm - txhim kho lossis txo cov nyhuv ntawm cov tshuaj.
Noj pentamidine nyob rau hauv parallel nrog Lantus ua rau muaj kev ntsia hlau loj nyob rau hauv cov piam thaj, qhov kev hloov pauv ntse los ntawm ib qho zuj zus mus rau qhov nce.

Feem ntau, cov tshuaj muaj cov tshuaj xyuas zoo. Tus nqi insulin glargin raug nyiaj npaum li cas? Tus nqi ntawm cov nyiaj hauv thaj tsam thaj tsam li 2500-4000 rubles.

Qhov tshuaj tsis tuaj yeem ua ke ua ke nrog lwm cov tshuaj insulin, nws tsis tuaj yeem xeb ua ntej siv, vim qhov no txo nws cov hauj lwm zoo. Yog tias sib xyaw nrog lwm cov tshuaj pharmacological, dej nag yog tau.

Txhawm rau kom ua tau zoo kho mob, Lantus yuav tsum tau siv txuas ntxiv, txhua txhua hnub nyob rau tib lub sijhawm.

Ntawm qhov tsis sib xws, hauv thawj hnub ntawm kev tswj hwm, kev nce ntxiv ntawm cov tshuaj insulin yog qhov ua tau kom thiaj li yuav zam tau hyperglycemia. Thaum txhua lub cev hloov mus rau txoj kev siv tshuaj tshiab zoo tshaj plaws, koj tuaj yeem txo qhov koob tshuaj rau tus nqi ib txwm.

Txhua yam kev hloov pauv hauv txoj kev kho, tshwj xeeb yog cov cuam tshuam nrog kev hloov cov tshuaj nrog cov tshuaj tiv thaiv kab mob analogues, yuav tsum pom zoo nrog cov kws kho mob koom nrog, uas paub tias ib hom tshuaj txawv ntawm lwm thiab qhov twg zoo dua.

Qhov yuav tsum tau siv rau lwm pab pawg ntawm cov tshuaj rau kev kho mob yuav tsum tau ceeb toom ua ntej rau tus kws kho mob uas koom nrog. Qee cov tshuaj, sib cuam tshuam nrog Lantus, txhim kho nws cov nyhuv, thaum lwm tus, ntawm qhov tsis tooj, inhibit nws, ua rau nws tsis tuaj yeem tau txais kev kho kom zoo.

Cov tshuaj uas txhim kho qhov kev txiav txim ntawm Lantus:

inhibitors
antimicrobial tus neeg sawv cev
ib pawg ntawm salicylates, fibrates,
Fluoxetine.

Lawv txoj kev tswj hwm tib lub sijhawm tuaj yeem ua rau cov ntshav qab zib dhia thiab cov ntshav glycemia muaj zog. Yog tias nws tsis tuaj yeem thim cov nyiaj no, nws yog ib qho tsim nyog yuav tau kho cov tshuaj ntawm cov tshuaj insulin.

Kev qaug zog ntawm qhov ua tau zoo ntawm cov tshuaj tuaj yeem tshwm sim thaum nws cuam tshuam nrog cov tshuaj diuretic, ib pawg estrogens thiab progestogens, thiab atypical antipsychotics. Cov tshuaj hormones kho mob los kho cov pathology ntawm cov thyroid caj pas thiab endocrine system tuaj yeem ua kom cov nyhuv hypoglycemic ntawm Lantus.

Nws raug nquahu kom tsis txhob haus dej haus cawv thiab siv cov tshuaj ntawm pawg beta-blocker rau kev kho, uas tuaj yeem txo ob txoj kev ua haujlwm ntawm cov tshuaj thiab ua rau glycemia, nyob ntawm qhov ntau npaum li cas thiab cov tib neeg cov yam ntxwv ntawm tus neeg mob lub cev.

Kev sib txuam tshuaj nrog ntau cov tshuaj tuaj yeem cuam tshuam cov metabolism hauv cov piam thaj. Cov tshuaj hauv qab no cuam tshuam rau kev nqis tes ntawm Lantus raws li cov lus qhia:

Cov tshuaj uas txhim kho qhov kev ua ntawm Lantus (insulin glargine) - ACE inhibitors, tshuaj tiv thaiv hypoglycemic, MAO inhibitors, fluoxetine, fibrates, disopyramides, propoxyphene, pentoxifylline, sulfonamide tshuaj thiab salicylates,
Cov tshuaj uas ua rau cov nyhuv tsis muaj zog ntawm Lantus (insulin glargine) - GCS, diazoxide, danazole, diuretics, gestagens, estrogens, glucagon, isoniazid, somatotropin, phenothiazine derivatives, sympathomimetics (epinephrine, terbutaline, salbutamolum), protease inhibitors los yog qee yam tshuaj tiv thaiv nerogen. cov thyroid hormones
Ob leeg txhim kho thiab ua kom cov nyhuv ntawm Lantus (insulin glargine) beta-blockers, lithium ntsev, clonidine, cawv,
Qhov tsis txaus ntseeg ntawm cov piam thaj hauv ntshav nrog kev hloov pauv ntawm hypoglycemia rau hyperglycemia tuaj yeem ua rau tib lub sijhawm tswj hwm ntawm Lantus nrog pentamidine,
Cov tsos mob ntawm adrenergic counterregulation tuaj yeem txo lossis ncua sijhawm thaum noj cov tshuaj sympatholytic - guanfacin, clonidine, reserpine thiab beta-blockers.

Txoj kev ntawm daim ntawv thov

Hauv kev siv, ua raws li txoj cai:

Cov lus qhia ntawm cov tshuaj yog nqa tawm hauv subcutaneous rog txheej ntawm tus ncej puab lossis lub xub pwg, pob tw, lub plhaw thawj thaj tsam. Cov tshuaj siv ib zaug ib hnub, thaj chaw txhaj tshuaj hloov, thiab kev sib luag sib luag yog tswj ntawm qhov hno tshuaj.
Qhov ntau npaum li cas thiab lub sijhawm ntawm kev txhaj tshuaj yog txiav txim los ntawm tus kws kho mob - cov kev txwv no yog tus neeg. Cov tshuaj siv tsuas yog siv ib leeg los yog ua ke nrog lwm cov tshuaj uas tsim los txo cov ntshav hauv qab ntuj.
Txoj kev txhaj tshuaj tsis haum lossis diluted nrog cov tshuaj insulin.
Cov tshuaj ua haujlwm zoo thaum muab tshuaj rau hauv qab daim tawv, yog li nws tsis pom zoo kom txhaj tshuaj rau qhov ntswg.
Thaum tus neeg mob hloov mus rau cov tshuaj insulin glargine, kev saib xyuas ntshav qab zib cov ntshav yog tsim nyog rau 14-21 hnub.

Thaum hloov cov tshuaj, cov kws tshwj xeeb xaiv cov txheej txheem raws li cov ntaub ntawv ntawm tus neeg mob tshuaj ntsuam thiab coj mus rau hauv tus yam ntxwv ntawm nws lub cev. Insulin rhiab heev dhau sij hawm vim kev txhim kho cov kev cai metabolic nce ntxiv, thiab kev pib qhov pib ntawm cov tshuaj yuav txawv.

Kev kho ntawm kev tswj hwm kuj yog qhov tsim nyog rau kev hloov pauv ntawm lub cev lub cev, hloov kev ua haujlwm, kev hloov pauv sai sai hauv txoj kev ua neej, uas yog, nrog rau cov ntsiab lus uas tuaj yeem ua rau lub siab rov qab rau qhov siab lossis qis qis qhov tseem ceeb.

Hauv cov neeg laus neeg laus, kev ploj zuj zus hauv lub raum ua haujlwm tuaj yeem ua rau cov insulin txuas ntxiv kom tsawg.

P / c. Cov neeg loj thiab me nyuam muaj hnub nyoog tshaj 2 xyoos.

Lantus® SoloStar® yuav tsum tau txhaj tshuaj sc ib zaug ib hnub nyob rau txhua lub sijhawm ntawm hnub, tab sis txhua hnub nyob rau tib lub sijhawm.

Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, Lantus® SoloStar ® tuaj yeem siv ob qho tib si li monotherapy thiab hauv kev sib xyaw nrog lwm cov tshuaj hypoglycemic.

Cov hom phiaj tseem ceeb ntawm cov piam thaj hauv cov ntshav, nrog rau cov koob tshuaj thiab lub sijhawm ntawm kev tswj hwm lossis kev tswj hwm ntawm cov tshuaj hypoglycemic yuav tsum txiav txim siab thiab kho tus kheej.

Kev hloov kho koob tshuaj kuj tseem yuav tsum tau ua, piv txwv li, thaum hloov tus neeg mob lub cev qhov hnyav, kev ua neej, hloov lub sijhawm ntawm kev saib xyuas ntawm cov tshuaj insulin, lossis lwm qhov xwm txheej uas yuav ua rau muaj kev cuam tshuam rau kev txhim kho hypo- lossis hyperglycemia (saib "Cov lus qhia tshwj xeeb"). Txhua qhov kev hloov pauv ntawm cov koob tshuaj insulin yuav tsum tau ua nrog ceev faj thiab kev saib xyuas mob.

Lantus® SoloStar® tsis yog qhov insulin ntawm kev xaiv rau kev kho mob ntshav qab zib ketoacidosis. Hauv qhov no, kev nyiam yuav tsum tau muab rau hauv / hauv kev qhia luv luv ntawm kev ua yeeb yam insulin.

Hauv cov txheej txheem kho mob suav nrog kev txhaj tshuaj insal basal thiab prandial insulin, 40-60% ntawm cov tshuaj insulin txhua hnub hauv daim ntawv ntawm insulin glargine feem ntau yog siv kom tau raws li qhov xav tau ntawm insulin basal.

Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, siv cov tshuaj hypoglycemic rau kev tswj hwm ntawm qhov ncauj, kev sib xyaw ua ke pib nrog ib koob tshuaj insulin glargine 10 PIECES ib hnub ib zaug, thiab hauv kev kho mob tom ntej yog kho tus kheej.

Hauv txhua tus neeg mob ntshav qab zib, soj ntsuam cov ntshav qabzib hauv siab pom zoo.

Hloov los ntawm kev kho mob nrog lwm cov tshuaj hypoglycemic rau Lantus® SoloStar®

Thaum hloov cov neeg mob los ntawm cov txheej txheem kev kho mob uas siv nruab nrab ntev lossis ntev ntev rau cov tshuaj insulin rau kev kho mob uas siv cov tshuaj Lantus® SoloStar® kev npaj, nws yuav tsim nyog kho qhov ntau (ntau npaum li cas) thiab lub sijhawm ntawm kev tswj hwm ntawm luv luv ua yeeb yam insulin lossis nws cov tshuaj tiv thaiv thaum nruab hnub lossis hloov cov tshuaj ntawm qhov ncauj hypoglycemic tshuaj Cov.

Thaum hloov cov neeg mob los ntawm ib qho kev txhaj tshuaj ntawm cov tshuaj insulin-isofan nyob rau ib hnub rau ib txoj kev tswj hwm ntawm cov tshuaj thaum nruab hnub, Lantus® SoloStar®, cov tshuaj tiv thaiv thawj zaug feem ntau tsis hloov pauv (i.e., qhov ntau ntawm U / hnub ntawm Lantus® SoloStar® tau siv, sib npaug ntawm tus nqi ntawm IU / hnub tshuaj insulin isophane).

Thaum hloov cov neeg mob los ntawm kev tswj hwm cov tshuaj insulin-isophan ob zaug thaum nruab hnub rau ib qho kev tswj hwm ntawm Lantus® SoloStar® ua ntej yuav mus pw kom txo qis kev pheej hmoo ntawm hypoglycemia thaum hmo ntuj thiab thaum sawv ntxov ntxov, qhov kev pib noj txhua hnub ntawm insulin glargine feem ntau yog txo 20% (piv nrog qhov tshuaj txhua hnub insulin-isophane), thiab tom qab ntawd nws raug hloov kho nyob ntawm tus neeg mob cov lus teb.

Lantus® SoloStar® yuav tsum tsis txhob sib xyaw nrog lwm cov tshuaj insulin los yog ua kom sib xyaw. Koj yuav tsum paub tseeb tias cov koob txhaj tshuaj tsis muaj cov tshuaj seem ntawm lwm cov tshuaj. Thaum muab sib xyaw los yog zom, qhov profile ntawm insulin glargine yuav hloov lub sijhawm.

Thaum hloov los ntawm tib neeg cov tshuaj insulin mus rau Lantus® SoloStar® thiab thaum thawj lub lis piam tom qab nws, ceev faj kev ntsuas metabolic (saib xyuas cov ntshav qabzib hauv cov ntshav) nyob rau hauv kev saib xyuas mob tau pom zoo, nrog kev kho cov tshuaj ntau ntxiv ntawm cov insulin yog tias tsim nyog.

Ib yam li lwm cov duab ntawm tib neeg cov tshuaj insulin, qhov no tshwj xeeb tshaj yog rau cov neeg mob, vim tias muaj cov tshuaj tiv thaiv rau tib neeg cov tshuaj insulin, yuav tsum tau siv cov koob tshuaj ntau kawg ntawm tib neeg cov insulin.

Hauv cov neeg mob no, thaum siv cov tshuaj insulin glargine, muaj kev txhim kho tseem ceeb rau cov tshuaj tiv thaiv kab mob insulin.

Txoj kev siv tshuaj Lantus® SoloStar®

Cov tshuaj Lantus® SoloStar ® raug muab tshuaj raws li s / c txhaj tshuaj. Tsis tau npaj rau kev tswj hwm iv.

Lub sijhawm ntev ntawm kev ua ntawm insulin glargine yog pom tsuas yog thaum nws qhia rau hauv cov rog subcutaneous. Hauv / hauv kev qhia ntawm cov tshuaj subcutaneous li niaj zaus tuaj yeem ua rau mob ntshav qab zib heev.

Lantus® SoloStar® yuav tsum tau txhaj rau cov roj ntsha hauv plab, xub pwg lossis lub duav. Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv nrog txhua qhov kev txhaj tshuaj tshiab hauv thaj chaw pom zoo rau kev tswj hwm sc ntawm cov tshuaj.

Xws li lwm hom tshuaj insulin, qhov siab ntawm kev nqus, thiab vim li ntawd qhov pib thiab lub sijhawm ntawm nws qhov kev ua, tuaj yeem hloov pauv nyob rau ntawm tus yam ntxwv ntawm lub cev thiab lwm yam kev hloov pauv ntawm tus neeg mob lub cev.

Lantus® SoloStar® yog cov kev daws teeb meem, tsis raug ncua. Yog li ntawd, rov kho dua ua ntej siv tsis tas.

Yog tias Lantus® SoloStar® Syringe Cwj mem tsis ua haujlwm, cov tshuaj insulin glargine tuaj yeem tshem tawm los ntawm daim cartridge mus rau hauv cov koob txhaj tshuaj (haum rau cov tshuaj insulin 100 IU / ml) thiab tsim nyog txhaj tshuaj.

Cov lus qhia rau kev siv thiab tuav ntawm cov xaum ua ntej xaum xaum SoloStar®

Ua ntej siv thawj zaug, rab koob xaum xaum yuav tsum khaws cia ntawm chav tsev li 1-2 teev.

Ua ntej siv, tshawb xyuas daim cartridge sab hauv daim ntawv xaum. Nws yuav tsum siv tsuas yog hais tias qhov kev daws teeb meem yog pob tshab, xim, tsis muaj qhov pom ntawm cov khoom thiab thiab zoo sib xws, cuam tshuam nrog dej.

Lub cev tsis siv SoloStar ® cov koob txhaj tshuaj yuav tsum tsis tau siv thiab muab pov tseg.

Txhawm rau tiv thaiv kev kis mob, tus cwj mem uas muaj menyuam qhwv ua ntej tsuas yog siv los ntawm ib tus neeg mob thiab yuav tsum tsis txhob hloov mus rau lwm tus.

Kev Siv SoloStar® Syringe Cwj mem

Ua ntej siv SoloStar® Syringe Cwj mem, ua tib zoo nyeem cov lus qhia siv.

Cov ntaub ntawv tseem ceeb ntawm kev siv SoloStar® Syringe Cwj mem

Ua ntej siv txhua qhov, ua tib zoo txuas lub koob tshiab rau daim duab xaum xaum thiab kev sim kev nyab xeeb. Tsuas siv cov koob uas txuam nrog SoloStar ® yuav tsum siv.

Cov kev tiv thaiv tshwj xeeb yuav tsum tau ceev faj kom tsis txhob muaj kev sib tsoo nrog kev siv koob thiab qhov kis tau ntawm kev kis tus kab mob.

Txawm li cas los xij koj yuav tsum siv SoloStar® koob txhaj tshuaj yog tias nws puas ntsoog lossis yog koj tsis paub meej tias nws yuav ua haujlwm tau zoo.

Nws yog ib txwm tsim nyog yuav tsum muaj SoloStar ring syringe cwj mem thaum koj poob lossis ua rau daim ntawv dhau ntawm SoloStar® koob txhaj tshuaj.

Ntu Kev Khaws Cia Cov Khoom yuav tsum kuaj xyuas nrog txoj cai khaws cia ntawm SoloStar® Syringe Cwj mem.

S / c, hauv cov roj ntsha hauv qab ntawm lub plab, sab xub pwg lossis ncej puab, ib txwm tib lub sijhawm 1 zaug hauv ib hnub. Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv nrog txhua qhov kev txhaj tshuaj tshiab hauv thaj chaw pom zoo rau kev tswj hwm sc ntawm cov tshuaj.

Hauv / hauv kev qhia ntawm cov koob tshuaj ib txwm, npaj rau sc tswj hwm, tuaj yeem ua rau kev txhim kho ntshav nce siab ntau dhau.

Cov koob tshuaj ntawm Lantus thiab lub sijhawm ntawm hnub rau nws cov kev taw qhia tau xaiv ib tus zuj zus. Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, Lantus tuaj yeem siv ob qho tib si li monotherapy thiab hauv kev sib xyaw nrog lwm cov tshuaj hypoglycemic.

Cov tshuaj ntawm glargine tsuas yog xaiv los ntawm tus kws kho mob koom nrog ib tus zuj zus rau txhua tus neeg mob. Qhov kev txhaj tshuaj yog ua rau subcutaneously hauv qhov rog quav hauv lub plab, hips, xub pwg. Qhov kev txhaj tshuaj yog txhaj ib zaug hauv ib hnub, nyob rau tib lub sijhawm. Thaum muaj kev sib cuam tshuam nrog lwm cov tshuaj noj los ntawm tus neeg mob, ua kom qaug zog los yog sib zog ntawm qhov kev ua tau yog ua tau.

Hloov cov tshuaj ntxiv ntawm glargine yog tias:

Kev hloov pauv ntawm cov duab sib dhos ntawm lub neej.
Qhov hnyav los sis ceeb thawj.
Noj Mov Pauv Hloov.
Kev phais mob.
Raum tsis ua haujlwm.
Kev kis mob.
Cov tsos mob ntawm hypo- lossis hyperthyroidism.

Glargin muaj ntau cov kev mob tshwm sim:

Muaj hws ntau.
Mob taub hau.
Lub plawv palpitations.
Khaus
O o.

Kev noj ntau dhau ua rau lub plab tsis nco qab yuav tsum zam.

Glargine cov npe lag luam yog Lantus, Lantus SoloStar, Insulin Glargine, Tujeo SoloStar. Cov tshuaj siv yog siv hauv kev kho tshuaj tiv thaiv kab mob ntshav qab zib insulin-mellitus hauv cov neeg laus thiab cov menyuam yaus hnub nyoog tshaj li rau xyoo. Glargine thiab analogues yog contraindicated nyob rau hauv cov ntaub ntawv ntawm hypersensitivity rau lawv lub Cheebtsam thiab cov menyuam yaus hnub nyoog qis dua 6 xyoo. Ceev faj yog siv thaum nqa tus menyuam thiab pub niam mis.

Kev siv cov glargine tso cai kom ua tiav cov nyhuv hypoglycemic tseem ceeb nrog qhov txo qis ntawm qhov tseem ceeb ntawm glycemia thiab glycated hemoglobin. Hloov chaw tej zaum yuav tsis zoo li.

Qhov tsis muaj qhov tseem ceeb contraindications, nrog rau kev ua haujlwm siab, yog qhov muaj txiaj ntsig txaus rau kev pom zoo rau cov neeg mob ntshav qab zib hom 2 rau kev kho mob nkaus xwb, nrog rau kev sib xyaw nrog cov piam thaj txo cov ntsiav tshuaj thiab luv luv insulins.

Lantus yog tsim los kho cov teeb meem cuam tshuam nrog theem siab thiab qis qab zib. Nws yuav tsum raug tswj tsuas yog nyob hauv qab ntawm daim tawv nqaij thiab raug txwv tsis pub - txog leeg.

Lub sijhawm ntev ua rau ntawm cov tshuaj yog vim qhov tseeb tias nws tau txhaj rau hauv cov rog subcutaneous. Peb yuav tsum tsis txhob hnov qab tias qhov kev qhia ntawm cov tshuaj ib txwm tso rau hauv tuaj yeem ua rau qhov kev txhim kho ntawm cov ntshav khov qis.

Ua cov txheej txheem ib hnub ib zaug tib lub sijhawm. Kev txhaj tshuaj rau hauv qhov ncauj kom zoo yuav tsum nruj me ntsis. Txhawm rau kom tsis txhob lipodystrophy, hloov thaj chaw txhaj tshuaj.

Cov koob tshuaj ntawm cov tshuaj yog nyob ntawm qhov hnyav ntawm tus neeg mob, nws txoj kev ua neej thiab lub sijhawm ntawm kev tswj hwm ntawm cov tshuaj. Nws yog tus xaiv los ntawm tus kws kho mob.

Nws tsis pom zoo kom dilute los yog sib xyaw Insulin Lantus nrog lwm cov tshuaj insulin. Qhov no tuaj yeem ua rau muaj kev hloov pauv hauv cov chaw muag tshuaj ntawm glargine.

Raws li cov lus qhia, Lantus (insulin glargine) yog qhia nyob rau hauv cov ntaub ntawv ntawm:

Hom I ntshav qab zib mellitus (insulin-dependant),
Hom Ntshav Qab Zib II mellitus (non-insulin-dependant) nyob rau theem ntawm kev ua rau kev cuam tshuam ntawm qhov ncauj ntawm cov tshuaj ntshav qab zib, cov kab mob sib kis thiab kev xeeb tub.

Txhawm rau siv Lantus raws li cov lus qhia, cov cai hauv qab no yuav tsum nruj me ntsis:

Txhawm rau hno cov tshuaj rau hauv cov nqaij ntshiv subcutaneous ntawm tus ncej puab, lub xub pwg, phab ntsa plab pem hauv ntej, pob tw nrawm nruj rau tib lub sijhawm, ib hnub ib zaug, hloov chaw txhaj tshuaj txhua hnub,
Cov koob tshuaj thiab lub sijhawm ntawm cov thawj coj yog xaiv tus kheej los ntawm tus kws kho mob koom nrog, kev kho mob lossis noj tshuaj nrog rau lwm cov tshuaj tiv thaiv ntshav qab zib raug tso cai,
Cov roj pleev txhaj tshuaj yuav tsum tsis txhob tov lossis sib xyaw nrog lwm cov tshuaj insulin,
Lantus yuav tsum tsis txhob ua haujlwm koob tshuaj, qhov ua tau zoo tshaj plaws ntawm cov tshuaj yog manifested nrog subcutaneous tswj hwm,
Thaum hloov mus rau Lantus los ntawm lwm cov tshuaj insulin, nws yog ib qho tsim nyog yuav tsum tau ua tib zoo saib xyuas ntshav qib ntshav hauv thawj 2-3 lub lis piam.

Tus txheej txheem ntawm kev hloov pauv los ntawm lwm cov tshuaj hypoglycemic mus rau Lantus yuav tsum yog tus kws kho mob tau koom nrog cov txiaj ntsig ntawm kev tshuaj xyuas mob, suav txog tus yam ntxwv ntawm tus neeg mob. Yav tom ntej, kev noj tshuaj ntau dua tuaj yeem hloov kho nrog kev nkag siab ntau ntxiv rau cov tshuaj insulin vim muaj kev txhim kho kev tswj ntawm cov metabolism.

Kev kho ntawm lub tswv yim kuj yuav xav tau thaum hloov txoj kev ua neej, kev ua neej, lub cev qhov hnyav, lossis nrog rau lwm yam ua rau kev nce siab ntawm kev mob siab rau hyper- lossis hypoglycemia.

Raws li cov lus qhia rau kev siv, insulin Lantus yog tshuaj rau:

mob ntshav qab zib insulin-hom mob ntshav qab zib hom (hom 1,)
non-insulin-daim ntawv foos ntawm tus kabmob (hom 2). Nws yog siv thaum cev xeeb tub, qhov tsis muaj txiaj ntsig ntawm qhov ncauj-txo cov tshuaj, muaj cov kab mob sib kis.

Cov lus qhia rau kev siv qhia tias cov tshuaj no muaj contraindicated:

thaum kev nkag siab ntawm lub cev mus rau cov tshuaj nquag lossis lwm yam ntxiv ntawm cov tshuaj ntxiv,
thaum kho ib tug menyuam yaus hnub nyoog qis dua 6 xyoo.

Hauv lub hlis ntawm cev xeeb tub, cov tshuaj yog coj raws li tus kws kho mob tshwj xeeb.

- mob ntshav qab zib mellitus xav tau cov tshuaj insulin rau cov laus, cov hluas thiab cov menyuam yaus hnub nyoog tshaj 6 xyoo.

Mob ntshav qab zib mellitus xav tau kev kho tshuaj insulin rau cov laus, cov hluas thiab menyuam yaus hnub nyoog ntau dua 2 xyoos.

ua kom lub siab tsis haum rau cov tshuaj insulin glargine lossis lwm yam kev pabcuam ntawm cov tshuaj,

cov menyuam yaus lub hnub nyoog txog 2 xyoos (tsis muaj cov ntaub ntawv hais txog kev siv).

Ceev faj: cov poj niam cev xeeb tub (muaj peev xwm hloov pauv tshuaj insulin thaum cev xeeb tub thiab tom qab yug menyuam).

Mob ntshav qab zib mellitus xav tau kev kho tshuaj insulin rau cov laus, cov hluas thiab cov menyuam yaus hnub nyoog tshaj 6 xyoo.

cov tshuaj tiv thaiv kab mob rau insulin glargine lossis rau ib qho ntawm cov neeg tsis sib haum,

cov menyuam yaus hnub nyoog qis dua 6 xyoo (tam sim no tsis muaj ntaub ntawv qhia txog kev siv).

Ceev faj yuav tsum siv rau hauv tus poj niam cev xeeb tub.

Insulin Lantus SoloStar yog siv rau cov ntshav qab zib ntawm ob hom hnub nyoog ntawm 6 xyoo.

Dab tsi yog cov contraindications rau kev siv tshuaj Lantus? Cov lus qhia rau kev siv cov tshuaj qhia pom ob pawg neeg ntawm cov neeg uas tau muab tshuaj rau contraindicated.

Tsis txhob siv cov tshuaj no rau hauv cov neeg mob uas ua xua nrog cov tshuaj nquag lossis ntxiv rau cov tshuaj ntxiv. Nov yog qhov tsuas yog contraindication rau kev siv tshuaj.

Nws tsis pom zoo kom siv cov tshuaj rau menyuam yaus hnub nyoog qis dua 2 xyoos, vim tias tsis muaj pov thawj tshawb pom los ntawm kev tshawb fawb hauv chaw kuaj mob tias nws muaj kev nyab xeeb.

Nws yog tshuaj rau cov neeg mob ntawm endocrinologist uas raug kev txom nyem los ntawm ob hom ntshav qab zib. Feem ntau cov no yog cov neeg laus thiab menyuam yaus hnub nyoog li ntawm 6 xyoo.

Nws tsis tuaj yeem raug kho rau cov neeg uas tsis mob siab rau rau cov khoom tseem ceeb thiab cov khoom siv ntxiv.

Lantus txwv tsis pub nqa mus rau cov neeg mob kev txom nyem los ntawm kev tso ntshav qab zib kom tsawg.

Txog kev kho mob rau menyuam yaus nrog cov tshuaj no, hauv kev kho menyuam yaus nws tuaj yeem siv los kho cov menyuam mos uas muaj hnub nyoog ntau dua ob xyoos.

Nws yog ib qho tseem ceeb kom nco ntsoov tias insulin glargine, uas yog ib feem ntawm Lantus, tsis yog ib yam khoom uas pab hauv kev kho mob ntshav qab zib ketoacidosis. Lwm lub ntsiab lus tseem ceeb yog hauv qab no: cov tshuaj yuav tsum tau siv nrog ceev faj rau cov neeg uas muaj kev phom sij thaum noj ntshav qis.

Nws yog txwv tsis pub siv insulin glargine rau cov neeg uas muaj kev fab tshuaj rau cov tshuaj no tshwm sim los ntawm kev tsis haum rau ib tug neeg. Kev siv ntawm Lantus Solostar raws li cov lus qhia los ntawm cov menyuam yaus hnub nyoog qis dua 6 xyoo yog txwv tsis pub siv. Nws tsuas yog siv los ntawm tus menyuam hlob dua. Cov tshuaj phiv:

ntshav qab zib,
tab kaum kev cuam tshuam,
lub paj hlwb tsis ua hauj lwm zoo,
kev ua xua ntawm daim tawv nqaij
pom kev pom
myalgia.

Cov kev mob tshwm sim rau cov tawv nqaij ua rau pob thiab khaus khaus pom nyob rau hauv cov neeg tsis tau muaj hnub nyoog 18-20 xyoo, thiab tus neeg mob hnub nyoog laus dua lub hnub nyoog tsis tshua muaj kev phiv los sis cov kev mob tshwm sim, feem ntau vim yog cov tib neeg cov yam ntxwv ntawm lub cev.

Kev mob ntshav qab zib yog ib yam ua rau cov ntshav qab zib tsawg, yog ib qho kev phiv rau cov neeg mob uas siv tshuaj insulin. Ntawm ib feem ntawm lub hauv nruab nrab lub paj hlwb, qhov ib txwm mloog zoo li nkees, txob taus, tsis nco qab thiab tsaug zog yuav tuaj yeem.

Tsaus muag thiab npaj ua ntej yuav tsaus muag yog qhov ua tau, muaj kev xav ntau heev ntawm xeev siab, mob taub hau, ntxhov siab rau ntawm ib feem ntawm kev nco qab, tsis meej pem ntawm kev nkag siab.

Ua rau muaj tshuaj tiv thaiv kab mob glycemia, tus neeg mob yuav muaj qhov tsis nco noj tsis tshaib plab, uas ua rau tus neeg tsis muaj peev xwm tswj hwm tus txheej txheem ntawm kev noj zaub mov. Cov qog pom tshwm, tawv nqaij daj ntseg, ua tawv tawv daj, tawm hws.

Qhov tshwm sim tsis zoo los ntawm lub cev tiv thaiv kab mob yog ua pob rau ntawm daim tawv nqaij, muaj kev pheej hmoo siab ntawm kev poob siab ntawm cov kab mob angioneurotic, bronchospasm. Daim duab cov tsos mob no tuaj yeem cuam tshuam rau cov neeg keeb kwm yav dhau los uas muaj cov kab mob ntev thiab ua kev hem thawj rau tus neeg mob lub neej.

Pom kev tsis zoo, raws li cov lus teb rau insulin, tsis tshua muaj tshwm sim. Pathology cuam tshuam nrog kev hloov pauv ntawm cov nqaij mos ntawm cov nqaij mos, uas yog ib ntus.

Tej zaum muaj kev ua txhaum ntawm tus txheej txheem ntawm kev ua kom rov qab zoo siab ntawm qhov muag teeb. Tsis tshua muaj txiaj ntsig, tab sis muaj feem tshwm sim ntawm Lantus yog myalgia - qhov mob ntawm qhov leeg mob hauv cov leeg.

Hauv thaj tsam ntawm kev tswj hwm tshuaj, muaj kev o me me, liab thiab khaus, qhov mob me me kuj tshwm sim. Cov nqaij mos o qhuav muaj qhov tsawg.

Nrog rau kev siv tsis yog ntawm Lantus, ib qho kev siv ntau tshaj yog ua tau, uas tau hais tawm hauv kev mob hnyav ntawm glycemia. Yog tias tsis muaj kev kho mob raws sijhawm, qhov xwm txheej no tuaj yeem ua rau tuag tau. Cov tsos mob ntawm ib qho kev noj haus ntau dhau yog qhov ua tsis taus pa, muaj kev cuam tshuam ntawm lub hauv nruab nrab cov hlab hlwb, ib qho mob ceev ntawm glycemia, coma.

Cov tshuaj Insulin Lantus muaj cov nyhuv ntev ntev, txhim kho cov metabolism hauv cov piam thaj thiab tswj cov metabolism hauv kev ua kom rog. Thaum noj tshuaj, qab zib kom tsawg los ntawm cov nqaij thiab cov nqaij rog yog ceev. Tsis tas li, tus neeg sawv cev hormonal ua kom cov protein ntau. Tib lub sijhawm, proteolysis thiab lipolysis hauv adipocytes yog inhibited.

Kev siv tshuaj Insulin Lantus tsis yog qhov tsim nyog rau kev tsis txaus ntseeg rau cov tshuaj nquag lossis cov khoom siv pabcuam. Rau cov tub ntxhais hluas, cov tshuaj tau hais tawm tsuas yog thaum lawv muaj 16 xyoo.

Kev saib xyuas tshwj xeeb yuav tsum tau coj thaum tsim kev loj hlob ntawm cov hlab ntsha hlwb ntau dua, kom lub cev ntawm cov hlab ntshav thiab cov hlab ntsha. Kev tshuaj ntsuam mob kuj tseem ceeb rau cov neeg mob uas cov tsos mob ntawm lub qog ntshav qab zib. Tus kab mob no tuaj yeem raug npog los ntawm kev puas siab puas ntsws, leeg mob hlwb, ntshav qab zib ntev.

Raws li cov lus qhia nruj, nws yog tshuaj rau cov neeg laus. Tib yam siv rau cov neeg uas tau hloov los ntawm insulin ntawm tsiaj keeb kwm rau tib neeg.

Raws li cov lus qhia Lantus yog contraindicated:

Nrog rau kev nkag siab ntxiv rau cov tshuaj insulin glargine lossis rau ib ntu twg ntawm cov tshuaj tiv thaiv,
Cov menyuam yaus hnub nyoog qis dua 6 xyoo.

Cov poj niam cev xeeb tub yuav tsum tau siv nrog ceev faj, nyob rau hauv kev saib xyuas ntawm tus kws kho mob.

Cov ntawv tso tawm thiab tus nqi ntawm cov tshuaj

Cov tshuaj nquag siv ntawm cov tshuaj yog cov tshuaj hormone glargine. Cov neeg zam kuj tseem ntxiv rau nws: zinc chloride, hydrochloric acid, m-cresol, sodium hydroxide, dej rau cov tshuaj thiab glycerol. Cov tshuaj no nws txawv ntawm ntau lwm yam tshuaj insulin hauv nws daim ntawv tso tawm.

OptiKlik - ib pob muaj 5 daim cartridges ntawm 3 ml txhua. Cartridges tau ua los ntawm cov iav ntshiab.
Daim duab syringe, siv yooj yim - nrog kov ntawm cov ntiv tes, kuj tseem tsim rau 3ml.
Lantus SoloStar daim cartridges muaj 3 ml ntawm cov tshuaj. Cov cartridges no tau nruab rau hauv cov xaum npuav. Muaj 5 npiv xws li hauv pob, tsuas yog lawv muag yam tsis muaj rab koob.

Cov tshuaj no yog cov tshuaj kho ntev. Tab sis pes tsawg Lantus insulin raug nqi?