Glimekomb - (Glimekomb) cov lus qhia rau siv

Daim ntawv koob tshuaj - ntsiav tshuaj: tiaj-cylindrical, los ntawm dawb mus dawb nrog creamy los yog daj tint (marbling xim yog muaj peev xwm ua tau), nrog kev nqis siab thiab ib qho bevel (10 pcs. Hauv pob ntawm contour hlwb, hauv ib daim ntawv thawv 6 pob, 20 pcs. cov hlwv, hauv ib daim ntawv qhwv ib pob 5 pob, 30, 60 thiab 120 pcs. hauv hwj yas, hauv duab los qhia ib pob 1 fwj).

Yam tshuaj muaj nyob hauv 1 ntsiav tshuaj:

• metformin hydrochloride - 500 mg,
• gliclazide - 40 mg.

Cov khoom siv ntxiv: croscarmellose sodium, povidone, magnesium stearate, sorbitol.

Kev ntsuas rau siv

• hom 2 mob ntshav qab zib mellitus thaum tsis muaj kev tiv thaiv kev noj zaub mov zoo, kev tawm dag zog thiab kev kho mob yav dhau los nrog tshuaj tua kab mob gliclazide lossis metformin,
• yam 2 mob ntshav qab zib mellitus nrog cov ntshav siab ruaj khov thiab tswj tau ntshav qabzib - los hloov kev kho ua ke dhau los nrog ob yam tshuaj (gliclazide thiab metformin).

Cov Yuav Tsum Tau Ua

• ntshav qab zib,
• ketoacidosis, mob ntshav qab zib precoma thiab coma,
• ntshav qab zib hom 1
• daim siab ua hauj lwm
• mob thiab mob mus ntev nrog cov nqaij mos hypoxia: tsis ntev los no myocardial infarction, ua pa thiab lub plawv tsis ua hauj lwm, poob siab,
• mob uas tuaj yeem ua rau lub raum hloov pauv tau: mob hnyav, lub cev qhuav dej, ceeb,
• mob raum tsis zoo,
• lactic acidosis, suav nrog keeb kwm ntawm
• cov kab mob sib kis, kev kub nyhiab, kev raug mob, kev phais mob hnyav thiab lwm yam mob uas yuav tsum muaj tshuaj tua kab mob,
• porphyria
• haus dej cawv txaus, mob cawv sij hawm ntev,
• ua raws li kev noj haus kom tsis txhob muaj calories ntau tsawg (tsawg dua 1000 calories / hnub),
• lub sijhawm cev xeeb tub thiab pub niam mis,
• ua kev ntsuas radioisotope lossis xoo hluav taws xob nrog kev qhia ntawm iodine-muaj qhov nruab nrab ntawm qhov nruab nrab (48 teev ua ntej thiab 48 teev tom qab),
• siv cov miconazole kom nruj,
• ua kom lub cev tsis haum rau ib qho nquag lossis pabcuam ntawm cov tshuaj lossis lwm yam sulfonylurea derivatives.

Glimecomb tsis pom zoo rau cov neeg mob hnub nyoog 60 xyoo uas ua haujlwm lub cev nyhav (vim qhov pheej hmoo ntawm kev tsim mob lactic acidosis).

• mob qog nrog kev ua txhaum ntawm nws txoj haujlwm,
• adrenal tsis txaus,
• febrile mob
• hypofunction ntawm lub anterior pituitary caj pas.

Tsuas tshuaj thiab tswj hwm

Glimecomb yuav tsum tau noj ntawm qhov ncauj thaum lossis noj mov tom qab noj mov tas.

Tus kws kho mob txiav txim siab muab koob tshuaj ib leeg zuj zus, nyob ntawm seb muaj ntshav qabzib nyob hauv cov ntshav.

Thawj koob tshuaj txhua hnub, raws li txoj cai, yog 1-3 ntsiav tshuaj, tom qab ntawd nws tau maj mam nce ntxiv, yog tias tsim nyog, kom txog thaum them nyiaj ruaj khov ntawm tus kabmob tuaj yeem ua tiav.

Qhov siab tshaj plaws niaj hnub noj yog 5 ntsiav tshuaj.

Qhov koob tshuaj txhua hnub feem ntau faib ua 2 koob - thaum sawv ntxov thiab yav tsaus ntuj.

Sab sij huam

• kev ua xua: maculopapular tawm pob, khaus, urticaria,
• los ntawm ib sab ntawm cov metabolism: nrog rau kev noj zaub mov tsis zoo thiab kev ua txhaum ntawm kev noj tshuaj - hypoglycemia (kev tshaib plab, mob taub hau, qaug zog, lub cev tsis muaj zog, kiv taub hau, nce tawm hws, ib ce mob ib ntus, ua tsis tiav ntawm kev txav mus los, palpitations, nrog kev nce ntawm hypoglycemia - poob ntawm kev tswj tus kheej thiab nco qab) , qee kis - mob lactic acidosis (mob plab, ua pa tsis haum, txo ntshav siab, nkees, myalgia, tsis muaj zog, mob ntshav qab zib, tsis nco qab caj dab),
• los ntawm cov ntshav hemopoietic plab hnyuv siab raum: tsis tshua muaj - inhibition ntawm cov pob txha mob hematopoiesis (thrombocytopenia, ua kom ntshav liab, leukopenia),
• los ntawm lub plab zom mov: ploj ntawm lub siab, ua tsis haum plab (mob tsis haum rau hauv lub qhov ncauj, zawv plab, xeev siab, hnov ​​qhov hnyav hauv lub sijhawm epigastrium), tsis tshua muaj - daim siab puas (muaj kev ua haujlwm ntau ntawm hepatic transaminases thiab alkaline phosphatase, cholestatic jaundice, kab mob siab),
• Lwm yam: tsis pom kev pom.

Cov lus qhia ntawm sulfonylureas, uas suav nrog ib qho ntawm cov khoom xyaw tseem ceeb ntawm Glimecomb (glyclazide), tuaj yeem ua rau cov kev mob tshwm sim hauv qab no: kev ua xua vasculitis, hemolytic anemia, agranulocytosis, pancytopenia, erythropenia, thiab lub siab ua rau lub siab tsis ua haujlwm.

Thaum muaj kev noj ntau dhau thiab nyob rau ntawm qhov muaj kev pheej hmoo vim tias cov tshuaj metformin uas yog ib feem ntawm cov tshuaj, kev txhim kho ntawm cov kab mob lactic acid yog ua tau - ib qho kev mob uas yuav tsum tau kho mob sai (nws cov tsos mob tau piav qhia saum toj no). Kev kho mob yuav tsum tau nqa tawm hauv tsev kho mob. Txoj kev kho mob zoo tshaj plaws rau cov kev mob no yog hemodialysis.

Tsis tas li, ib qho kev tshaj tawm tuaj yeem ua rau kev loj hlob ntawm hypoglycemia, vim tias gliclazide yog ib feem ntawm cov tshuaj. Nrog rau qhov hnyav mus rau mob hnyav ntawm cov ntshav qog ntshav qab zib, qabzib (dextrose) yuav tsum tau muab tshuaj lossis qab zib daws qhov ncauj. Hauv cov ntshav qog ntshav hnyav (uas tsis nco qab lawm) 40% cov kua nplaum (dextrose) daws tau txhaj rau cov tshuaj, ntshav qab zib lossis ntshav qab zib. Tom qab tus neeg mob rov qab nco qab, nws yuav tsum tau noj cov khoom noj uas muaj cov khoom noj carbohydrate kom tiv thaiv kev rov qab txhim kho hypoglycemia.

Cov lus qhia tshwj xeeb

Glimecomb tsuas yog kho rau cov neeg mob uas tau txais zaub mov tsis tu ncua nrog cov ntsiab lus carbohydrate tsawg, uas suav nrog pluas tshais.

Thaum kho, koj yuav tsum tau soj qab xyuas kom cov qib ntawm cov piam thaj hauv cov ntshav ntawm lub plab thiab tom qab noj mov, tshwj xeeb tshaj yog nyob rau thawj hnub ntawm kev noj tshuaj.

Glimecomb yuav tsum tau tsum tsum tsis pub puv 48 teev ua ntej kev tso dej khov ntawm cov tshuaj iodine muaj radiopaque tus neeg sawv cev lossis kev phais mob. Koj tuaj yeem rov noj sijhawm tsis pub dhau 48 teev.

Nws yuav tsum tau yug los hauv lub siab tias sulfonylurea derivatives (hauv qhov no, glyclazide) tuaj yeem ua rau mob ntshav qab zib (hypoglycemia), qee qhov xwm txheej hauv daim ntawv loj thiab lub caij nyoog. Feem ntau, qhov xwm txheej no tsim tawm nrog cov zaub mov tsis muaj calorie ntau, tom qab siv zog lossis ua kom lub cev ntev dhau, tom qab haus cawv, nrog rau thaum noj ntau yam tshuaj hypoglycemic. Txhawm rau kom zam dhau kev txhim kho hypoglycemia, nws yuav tsum ua tib zoo xaiv ib qho tshuaj rau txhua tus neeg mob thiab muab nws cov ntaub ntawv tiav ntawm cov kev kho mob uas yuav tuaj tom ntej no.

Cov koob tshuaj ntawm Glimecomb yuav tsum tau kho thaum hloov pauv kev noj haus, nrog kev mob siab thiab lub cev.

Cov neeg mob hauv qab no yog tshwj xeeb tshaj yog kev cuam tshuam ntawm kev txiav txim ntawm cov tshuaj hypoglycemic:

• cov neeg mob pituitary-adrenal tsis txaus,
• neeg laus neeg laus
• cov neeg uas tsis tau noj zaub mov zoo,
• cov neeg mob uas muaj lub zog tsis tu ncua lub xeev.

Kev tshaib plab, haus dej cawv thiab cov tshuaj uas tsis yog tshuaj steroidal txhawb txoj kev pheej hmoo ntawm ntshav qab zib.

Guanethidine, reserpine, clonidine thiab beta-blockers tuaj yeem npog qhov chaw kuaj ntshav ntawm hypoglycemia.

Hauv cov kab mob sib kis nrog febrile syndrome, kev kub hnyiab ntev, kev raug mob thiab kev phais mob hnyav, Kev Txiav Txim Siab Glimecomb thiab kev teem sijhawm kho tshuaj insulin tej zaum yuav tsum tau ua. Thaum kho, nws yog ib qho tsim nyog yuav tau soj ntsuam lub raum thiab lub sijhawm (tsawg kawg 2 zaug hauv ib xyoos) txiav txim rau lactate hauv ntshav. Nyob rau hauv cov ntaub ntawv ntawm lactic acidosis, nws yog ib qho tsim nyog kom thim tawm cov tshuaj.

Thaum npaj lub cev xeeb tub thiab thaum muaj tshwm sim thaum siv tshuaj, nws yog qhov yuav tsum tau tsum tsis txhob noj tshuaj thiab tawm kev siv tshuaj insulin.

Thaum kho lub sijhawm, haus cawv kom txwv. Kev ceev faj yuav tsum tau siv thaum tsav tsheb thiab ua cov haujlwm muaj feem phom sij uas yuav tsum muaj kev saib xyuas ntau dua, qhov ceev ntawm lub hlwb thiab lub cev muaj zog.

Yeeb tshuaj sib cuam tshuam

Cov nyhuv hypoglycemic ntawm Glimecomb yog kho kom zoo los ntawm lwm cov kab mob hypoglycemic (xws li, insulin, acarbose, biguanides), tubular secretion blockers, ntev ua yeeb yam sulfonamides, blockers N₂histamine receptor antagonists (e.g. cimetidine), coumarin anticoagulants, noj cov tshuaj mas siv (fluconazole, miconazole), ACE inhibitors (enalapril, captopril), beta-blockers, salicylates, nonsteroidal anti-inflammatory siv tshuaj (oxyphenbutazone, azapropazone, phenylbutazone), monoamine oxidase inhibitors , tshuaj tiv thaiv kab mob TB (ethionamide), fibrates (clofibrate, bezafibrate), anabolic steroids, oxytetracycline, fenfluramine, disopyramide, tetracycline, guanethidine, fluoxetine, c cyclophosphamide, allopurinol, reserpine, chloramphenicol, pyridoxine, theophylline, pentoxifylline, bromocriptine.

Hypoglycemic txiav txim Glimekomba tsis muaj zog carbonic anhydrase inhibitors (acetazolamide), thiazide diuretics, lithium, anti-epileptic tshuaj (phenytoin), cov thyroid hormones blockers qeeb calcium raws, steroids, barbiturates, agonists (epinephrine, clonidine), rifampicin, baclofen, chlorthalidone, diazoxide, furosemide, glucagon, isoniazid, triamteren, terbutaline, morphine, asparaginase, salbutamol, danazol, ritodrin, hauv kev txhaj tshuaj ntau - qhov ncauj tiv thaiv kab mob, estrogens, chlorpromazine, nicotine hydrochloric acid.

Cov tshuaj uas inhibit pob txha mob hematopoiesis nce rau kev muaj peev xwm ntawm myelosuppression, ethanol - txoj kev txhim kho ntawm lactic acidosis.

Kev sib xyaw ua ke nrog kev mob plawv glycosides, Glimecomb nce kev pheej hmoo ntawm ventricular extrasystole.

Nifedipine ua rau kom nqus tau thiab ua rau qeeb ntawm kev txiav tawm cov tshuaj metformin.

Nrog rau siv ntev, cov kab mob cationic zais cia hauv cov tubules (procainamide, amiloride, vancomycin, quinine, quinidine, digoxin, triamteren, morphine, ranitidine) nce qhov siab tshaj plaws ntawm metformin hauv cov ntshav los ntawm 60%, furosemide - los ntawm 22%.

Metformin txo qhov kev xav ntau thiab ib nrab ntawm lub neej ntawm furosemide los ntawm 31 thiab 42.3%, ntsig txog.

Daim ntawv tso tawm, ntim thiab muaj pes tsawg leeg Glimecomb ®

Cov ntsiav tshuaj los ntawm dawb rau dawb nrog creamy lossis daj daj zas, tiaj tus cylindrical, nrog chamfer thiab kev pheej hmoo, marbling raug tso cai.

Tshwjxeeb: sorbitol, povidone, croscarmellose sodium, magnesium stearate.

10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.

Pharmacological kev txiav txim

Sib xyaw tshuaj hypoglycemic rau kev siv lub qhov ncauj. Glimecomb® yog kev sib xyaw ua ke ntawm ob lub qhov ncauj hypoglycemic ntawm cov pab pawg biguanide thiab sulfonylurea pawg.

Nws muaj pancreatic thiab extrapancreatic kev txiav txim.

Glyclazide yog sulfonylurea derivative. Stimulates ua rau cov kua dej tso tawm los ntawm tus txiav, nce qhov rhiab ntawm peripheral cov ntaub so ntswg rau insulin. Tsim kho kev ua ub no ntawm intracellular enzymes - nqaij hlav glycogen synthetase. Nws rov kho lub sijhawm thaum kawg ntawm cov tshuaj insulin secretion, txo lub sijhawm ncua sijhawm ntawm lub sijhawm noj mov kom txog thaum pib lub cev insulin, thiab txo qis postprandial hyperglycemia. Ntxiv nrog rau cuam tshuam rau cov metabolism hauv kev ua haujlwm, nws cuam tshuam microcirculation, txo platelet adhesion thiab kev sib sau ua ke, qeeb kev txhim kho ntawm parietal thrombosis, normalizes vascular permeability thiab inhibits kev txhim kho ntawm microthrombosis thiab atherosclerosis, rov qab cov txheej txheem ntawm physiological parietal fibrinolysis, thiab tawm tsam cov tshuaj tiv thaiv muaj zog rau vascular adrenal. Txo cov kev loj hlob ntawm cov ntshav qab zib retinopathy nyob rau theem tsis-loj hlob, nrog rau cov ntshav qab zib uas muaj lub cev ntev nrog kev siv ntev, qhov tseem ceeb txo qis rau cov proteinuria tau sau tseg. Nws tsis ua rau kom nce hauv lub cev nyhav, vim nws muaj cov teebmeem tseem ceeb ntawm kev xav thaum ntxov ntawm insulin secretion thiab tsis ua rau hyperinsulinemia, pab txo lub cev qhov hnyav hauv cov neeg mob rog, ua raws li kev noj zaub mov kom tsim nyog.

Metformin belongs rau cov pab pawg ntawm cov loj loj. Nws txo cov concentration ntawm cov piam thaj hauv cov ntshav los ntawm inhibiting gluconeogenesis nyob rau hauv daim siab, txo qhov nqus ntawm cov piam thaj los ntawm cov hnyuv thiab ua kom nws cov kev siv hauv cov ntaub so ntswg. Nws txo qhov concentration ntawm triglycerides, roj (cholesterol) thiab LDL (txiav txim siab ntawm lub plab khoob) hauv cov ntshav cov ntshav thiab tsis hloov lub siab ntawm lipoproteins ntawm ntau qhov sib txawv. Pab ua kom ruaj khov lossis txo lub cev qhov hnyav. Thaum tsis muaj cov tshuaj insulin nyob rau hauv cov ntshav, kev kho mob tsis pom tseeb. Kev ua kom lub cev ntshav qis tsis tuaj yeem ua. Txhim kho cov khoom fibrinolytic ntawm cov ntshav vim los ntawm kev tsuj ntawm ib qho inhibitor ntawm activator profibrinolysin (plasminogen) cov ntaub so ntswg hom.

Cov ntsiab lus ntawm nosological pawg

Cov Tshuaj Pharmacokinetics

Xuas thiab faib khoom

Tom qab kev tswj hwm ntawm qhov ncauj, nqus tau yog siab. Thaum noj nyob rau hauv ib koob ntawm 40 mg C max hauv cov ntshav plasma tau mus txog tom qab 2-3 teev thiab ntau npaum li 2-3 μg / ml. Plasma protein khi yog 85-97%.

Kev ntsuas phoo thiab nthuav tawm

Cov tshuaj txiav tawm hauv daim siab. T 1/2 - 8-20 teev. Nws raug nthuav tawm ntau hauv cov qauv ntawm cov khoom siv metabolites los ntawm ob lub raum - 70%, los ntawm txoj hnyuv - 12%.

Hauv cov neeg mob laus, cov kab mob tseem ceeb hloov hauv pharmacokinetic tsis tau pom.

Xuas thiab faib khoom

Tom qab kev tswj hwm ntawm qhov ncauj, qhov nqus tau yog 48-52%. Sai sai nqus los ntawm cov hnyuv. Kev tsis txaus siab txog kev noj qab haus huv (ntawm lub plab khoob) yog 50-60%. C max hauv cov ntshav ntshav tau mus txog tom qab 1.81-2.69 h thiab tsis pub tshaj 1 μg / ml. Txais tos nrog cov zaub mov txo C max hauv plasma los ntawm 40% thiab txo nws qhov ua tiav los ntawm 35 feeb. Plasma protein khi yog negligible. Metformin muaj peev xwm khaws ntau ntxiv hauv cov ntshav liab.

T 1/2 yog 6.2 teev .Nws yog tawm los ntawm lub raum, feem ntau tsis hloov pauv (glomerular pom thiab tubular tso zis) thiab los ntawm cov hnyuv (txog 30%).

Cov nqi hauv cov khw muag tshuaj hauv Moscow

Tso koj saib

Cov Ntaub Ntawv Tam Sim No Xav Tau Index, ‰

Cov ntawv pov thawj rau npe Glimecomb ®

• LSR-009886/09

Lub vev xaib raug cai ntawm lub tuam txhab RLS ®. Lub encyclopedia tseem ceeb ntawm cov tshuaj thiab cov khoom muag ntawm cov khw muag tshuaj assortment ntawm Lavxias Internet. Daim ntawv teev cov tshuaj Rlsnet.ru muab cov neeg siv kev nkag mus rau cov lus qhia, tus nqi thiab cov lus piav qhia txog cov tshuaj, khoom noj tshuaj, khoom siv kho mob, khoom siv kho mob thiab lwm yam khoom lag luam. Cov lus qhia ntawm pharmacological suav nrog cov ntaub ntawv ntawm kev sib xyaw thiab daim ntawv tso tawm, kev nqis tes ua pharmacological, kev taw qhia rau kev siv, contraindications, kev phiv tshuaj, cuam tshuam tshuaj, hom kev siv tshuaj, cov tuam txhab tshuaj. Daim ntawv qhia cov tshuaj muaj nqi rau tshuaj thiab cov khoom lag luam tshuaj hauv Moscow thiab lwm lub nroog Lavxias.

Nws yog txwv tsis pub xa, theej, tshaj tawm cov ntaub ntawv yam tsis tau txais kev tso cai los ntawm RLS-Patent LLC.
Thaum hais cov ntaub ntawv xov xwm luam tawm nyob rau ntawm nplooj ntawv ntawm lub xaib www.rlsnet.ru, qhov txuas mus rau qhov chaw ntawm cov ntaub ntawv xav tau.

Ntau ntau yam nthuav

Qoob loo.

Kev ua lag luam siv cov ntaub ntawv tsis raug tso cai.

Cov ntaub ntawv yog npaj rau cov kws kho mob.

Thov

Glimecomb raug pom zoo rau siv rau hauv cov neeg mob uas kuaj pom tus mob ntshav qab zib hom 2. Nws yog ib qho tseem ceeb tias cov tshuaj no yog tsom rau xws li kev mob tshwm sim thaum muaj kev tawm dag zog thiab daim ntawv qhia zaub mov tshwj xeeb tsis coj cov txiaj ntsig tsim nyog. Qhov no txhais tau tias cov tshuaj no tau sau tseg rau hauv kev ua tsis tiav ntawm kev kho txoj kev kho mob, sib txuas nrog ob yam tshuaj (feem ntau sib cais nrog metformin thiab gliclazide) nrog rau kev ua haujlwm ntawm lub cev thiab kev noj haus.

Thaum kho nrog Glimecomb, kev tshuaj xyuas cov ntshav qab zib kom tsawg ntawm tus neeg mob ua ntej thiab tom qab noj mov yog qhov tsim nyog (tshwj xeeb yuav tsum them rau thawj lub lim tiam ntawm kev nkag mus).

Tso Tawm Cov Ntawv

Glimecomb muaj kev tso tawm ib qho hauv daim ntawv ntawm cov ntsiav tshuaj. Cov tshuaj raug faib los ntawm cov txheej txheem ntawm kev ntim rau hauv cov pawg hauv qab no:

• hauv cov yas hwj hauv pob ntawv thawv. Ib lub vial ntawd ntim tau 30, 60 lossis 120 ntsiav tshuaj,
• hauv daim thawv ntawv thawv nrog blisters ntawm 10 ntsiav tshuaj hauv ib qho. Ib pob muaj 6 lub hlwv,
• nyob rau hauv ib lub thawv ntawv thawv nrog lub hlwv ntawm 20 ntsiav tshuaj hauv ib qho. Ib lub pob ntawd muaj 5 lub hlwv.

Cov ntsiav tshuaj lawv tus kheej yog nyob rau hauv daim ntawv ntawm cov tiaj tus kheej kheej, feem ntau dawb (beige, marble lossis daj yog siv tau). Tshuaj tua kab mob muaj qhov pheej hmoo thiab ib qho bevel. Qhov sib xyaw ua ke ntawm Glimecomb suav nrog metformin thiab hydrochloride hauv ib qho npaum li 500 mg, zoo li glycoslide 40 mg. Tsis tas li ntawd, povidone, magnesium stearate, sorbitol thiab croscarmellose sodium yog tam sim no cov khoom me me.

Kev taw qhia ntawm cov tshuaj Glimecomb ®

• hom 2 mob ntshav qab zib mellitus (non-insulin dependant) nrog qhov tsis muaj txiaj ntsig ntawm kev kho kev noj haus, kev tawm dag zog thiab kev kho mob yav dhau los nrog metformin lossis gliclazide,
• hloov cov kev kho mob yav dhau los nrog ob yam tshuaj (metformin thiab gliclazide) hauv cov neeg mob uas muaj ntshav qab zib hom 2 (tsis-insulin-tiv thaiv) nrog cov ntshav khov thiab tswj tau ntshav qabzib.

Cov lus qhia rau kev siv

Glimecomb noj qhov ncauj, tam sim ntawd tom qab noj mov lossis nrog nws, nyob ntawm kev ntau npaum li cas. Thaum kho nrog cov ntsiav tshuaj, koj yuav tsum ua raws li cov zaub mov carb qis uas cov kws tshaj lij pom zoo, uas yuav tsum muaj noj tshais. Cov koob tshuaj ntawm cov ntsiav tshuaj yuav tsum coj mus rau hauv tus account tsis tsuas yog cov neeg mob ntshav qab zib mellitus ntawm hom thib ob, tab sis kuj hais txog kev xav thiab lub cev ntawm tus neeg mob. Tsis tas li, kev hloov pauv ntawm kev noj haus yauv tsum muaj kev sib koom tes nrog kws kho mob (yoo mov thiab haus cawv tsis txaus ntseeg). Nws yog ib qho tsim nyog yuav tsum tau khaws cov tshuaj rau hauv qhov chaw qhuav, tsaus ntawm qhov kub ntawm qhov siab tsis tshaj 25 degrees Celsius. Txee lub neej 2 xyoos.

Nws yuav tsum nco ntsoov tias sulfonylurea cov khoom muaj nyob hauv cov tshuaj tuaj yeem ua rau mob ntshav qab zib. Txhawm rau zam qhov no, ua tib zoo xaiv cov koob tshuaj thiab zaub mov noj rau txhua tus neeg mob yog qhov tsim nyog. Thaum kho, yuav tsum tau saib xyuas tshwj xeeb thaum tsav tsheb thiab ua haujlwm uas yuav tsum muaj kev kub siab thiab nce siab ntxiv.

Kev noj tshuaj ntxiv

Cov tshuaj yog noj qhov ncauj thaum lub sijhawm lossis tom qab noj mov tas. Qhov ntau thiab tsawg ntawm cov tshuaj tau txiav txim los ntawm tus kws kho mob tshwj xeeb rau txhua tus neeg mob, nyob ntawm seb cov ntshav nyob ntawm seb ntau npaum li cas.

Thawj koob tshuaj feem ntau yog 1-3 ntsiav tshuaj / hnub nrog maj mam xaiv cov koob tshuaj kom txog thaum them nyiaj ruaj khov ntawm tus kabmob. Qhov siab tshaj plaws niaj hnub noj yog 5 ntsiav tshuaj.

Feem ntau cov tshuaj no yuav noj 2 zaug / hnub (sawv ntxov thiab yav tsaus ntuj).

Sab sij huam

Cov kev mob tsis txaus siab uas tuaj yeem ntsib thaum noj Glimecomb feem ntau vim tias nws noj ntau dhau lossis tsis sib xws nrog tus neeg mob lub cev tshwj xeeb. Thiab cov ntsiab lus ntawm sulfonylurea derivatives ua rau muaj kev pheej hmoo ntau ntawm cov kev mob tshwm sim. Kev xaiv koob tsis raug rau tus neeg mob yog fraught nrog kev txhim kho ntawm cov kab mob lactic acidosis, nrog rau yastaw yauv tawm, tsis muaj zog ib ce, qhov siab ntawm nkees, nrog rau kev txiav mob rau hauv thaj chaw hauv plab thiab txo qis siab hauv cov hlab ntsha.

Cov hauv qab no yog cov tsis xav tau qhov cuam tshuam thaum noj Glimecomb:

• kev txhim kho ntawm hypoglycemia thiab lactocidosis nrog txhua yam mob mob tshwm sim,
• cov tsos ntawm zawv plab thiab flatulence,
• tas li tsis kaj siab lom zem nyob rau hauv lub plab kab noj hniav,
• txo hauv kev tshaib plab,
• qee zaus tshwm sim ntawm kev saj ntawm cov ntshav hauv lub qhov ncauj thiab lub caj pas,
• kev txhim kho ntawm daim siab mob siab (kab mob siab, thiab lwm yam) muaj tsawg
• kev tsis haum tshuaj rau cov khoom siv ntawm cov muaj pes tsawg leeg (urticaria, khaus, qog,
• ua pob liab liab, ntau hom pob khaus),
• muaj cov xwm txheej tsis pom kev zoo thaum noj Glimecomb.

Yog tias koj muaj cov tsos mob saum toj no, koj yuav tsum tau sab laj nrog tus kws kho mob tshwj xeeb.

Hauv cov chaw muag tshuaj ntawm Lavxias, tus nqi ntawm Glimecomb nws txawv ntawm 200 txog 600 rubles, nyob ntawm qhov ntim thiab cov naj npawb ntawm cov ntsiav tshuaj hauv nws, kuj yog raws li tus xa khoom thiab thaj chaw muag. Tus nqi ntawm cov tshuaj no ua rau nws pheej yig heev rau ntau qhov ntawm cov pej xeem, thiab yog li ntawd hauv kev thov ntawm cov khw muag tshuaj. Yog li tus nqi nruab nrab hauv khw hauv online rau Glimecomb ntsiav tshuaj yog 40 mg + 500 mg 450 rubles rau ib pob, uas muaj 60 ntsiav tshuaj. Hauv cov khw muag tshuaj hauv lub network, tus nqi ntawm cov tshuaj rau 60 ntsiav tshuaj yuav yog li 500-550 rubles.

Glimecomb analogues yog cov tshuaj hauv qab no:

• Gliformin (txog 250 rubles rau 60 ntsiav tshuaj), lub hauv paus ntsiab lus ntawm kev ua yog tib yam li ntawm Glimecomb, qhov muaj pes tsawg leeg yog qhov zoo ib yam, tab sis qhov muaj cov tshuaj insulin ua rau cov tshuaj no tsawg dua,
• Diabefarm (rau 60 ntsiav tshuaj, koj yuav tsum tau them nyiaj txog 150 rubles). Nws muaj cov tshuaj muaj zog ntau dua ntawm glyclazide - 80 mg, tsom rau kev tshem tawm tib cov teeb meem zoo li Glimecomb.
• Gliclazide MV (tus nqi nruab nrab rau 60 ntsiav tshuaj yog 200 rubles). Nws muaj cov khoom sib txawv los ntawm Glimecomb, nws tsuas muaj 30 mg ntawm glycoslazide. Kev qhia rau kev siv yog tib yam li nyob hauv cov tshuaj qub.

Noj ntau dhau

Nyob rau hauv rooj plaub ntawm kev noj tshuaj ntau dhau ntawm Glimecomb, lactacidosis thiab hypoglycemia tshwm sim. Txhawm rau tiv thaiv cov mob no, tshuaj kho mob hemodialysis feem ntau tau kho. Glycemia yuav tsum tau siv cov piam thaj lossis ib qho kev daws teeb meem qab zib sab hauv (nrog mob hnyav lossis mob hnyav). Hauv ntau qhov xwm txheej hnyav, txog li qhov tsis nco qab, yuav tsum tau siv tshuaj daws ntshav qab zib 50% (tuaj yeem hloov nrog glucagon). Sai li tus neeg mob rov qab nco qab, nws yog ib qhov tsim nyog los muab nws cov khoom noj uas muaj cov khoom noj khoom haus siab kom ua rau nws txhawm rau tiv thaiv kev nce qib ntawm cov ntshav qab zib tsawg.

Thiab, yog tias kev haus cawv tshwm sim yam tsis muaj teeb meem loj, tus neeg mob yuav hnov ​​zoo li tsis tsaug zog txog qhov tsaus muag, xeev siab, mob plab thiab raws plab, nrog rau yob yoos yauv. Hauv qhov no, koj yuav tsum thov kev pab tam sim. Nyob hauv tsev, nws yog ib qho tsim nyog los yaug lub plab thiab tam sim ntawd tshem tawm cov tshuaj tawm ntawm cov hnyuv, tom qab los ntawm kev noj zaub mov nplua nuj hauv carbohydrates. Yog tias tsim nyog, yuav tsum tau pw hauv tsev kho mob tau raws li kev saib xyuas tas li ntawm tus kws tshaj lij.

Qhov kev ua tau zoo ntawm cov tshuaj no dhau los tswj cov ntshav qab zib hauv ntshav qab zib ntawm hom thib ob, nrog rau nws cov nqi nruab nrab, ua rau cov tshuaj nrov heev thiab tau txais ntau cov kev tshuaj xyuas zoo. Tab sis tsis txhob hnov ​​qab txog kev phiv los ntawm cov tshuaj no. Nws yog vim tias cov npe loj uas tsis xav tau uas pom qhov tsis zoo ntawm cov neeg mob tau pom. Hauv qab no yog qee qhov kev txheeb xyuas txog cov tshuaj no:

Glimecomb, raws li kev xyaum qhia, yog ib yam tshuaj uas nrov hauv kev kho mob ntshav qab zib hom 2. Kev sib xyaw ua ke ntawm tus nqi, kev ua tau zoo thiab kev ua haujlwm siab tau ua rau cov ntsiav tshuaj tshwj xeeb hauv cov khw muag tshuaj.

Sab sij huam

Los ntawm cov kab mob endocrine: hypoglycemia (kev ua txhaum ntawm txoj kev noj tshuaj ntau thiab noj zaub mov tsis txaus) - mob taub hau, nkees, tshaib plab, tawm hws, mob tsis muaj zog, mob plab, kiv taub hau, ua tsis tau haujlwm ntawm kev txav mus los, ib ntus ntawm lub cev tsis zoo, nrog kev txhim kho ntawm hypoglycemia, poob ntawm kev tswj tus kheej tau, tsis nco qab.

Los ntawm ib sab ntawm cov metabolism: hauv qee kis - lactic acidosis (tsis muaj zog, myalgia, ua pa tsis haum, tsaug zog, mob plab, hypothermia, txo ntshav siab, bradyarrhythmia).

Los ntawm lub plab zom mov: dyspepsia (xeev siab, zawv plab, zoo nkaus li qhov hnyav hauv lub phaum epigastrium, saj "xim hlau" hauv qhov ncauj), qab los noj tsawg (qhov tsis zoo ntawm cov tshuaj no yuav txo qis nrog cov tshuaj thaum noj mov), tsis tshua muaj kab mob siab, mob siab daj ntseg (noj tshuaj tawm) , nce kev ua si ntawm hepatic transaminases, alkaline phosphatase.

Los ntawm cov kab mob hemopoietic: tsis tshua muaj - inhibition ntawm cov pob txha mob hematopoiesis (mob ntshav qab zib, thrombocytopenia, leukopenia).

Ua xua: khaus, urticaria, maculopapular pob.

Lwm yam: tsis pom kev pom.

Yog tias muaj kev mob tshwm sim, qhov koob tshuaj yuav tsum raug txo lossis cov tshuaj txuas mus ib ntus.

Cov kev mob tshwm sim ntawm sulfonylurea derivatives: erythropenia, agranulocytosis, hemolytic anemia, pancytopenia, kev tsis haum vasculitis, ua rau lub siab ua rau lub siab tsis ua haujlwm.