600 ml / min (10 ml / s) thiab 50 ml / min (0.83 ml / s), feem, kev ua kom lub raum

74 ml / min (1.23 ml / s) thiab 26 ml / min (0.43 ml / s), raws li. T_1/2 (ib nrab-lub neej) ntawm losartan - 2 teev, metabolite EXP-3174 - 6–9 teev. Kwv yees li 58% ntawm cov tshuaj tau tawm nrog cov kua tsib, txog 35% - los ntawm lub raum.

Pharmacokinetic cov yam ntxwv ntawm hydrochlorothiazide:

• kev nqus thiab faib tawm: nqus tau tom qab kev tswj hwm ntawm qhov ncauj yog li ntawm 60 txog 80%. C_max hauv cov ntshav plasma tau ncav cuag tom qab 1-5 teev. Mus txog 64% ntawm cov khoom sib txuas rau cov ntshav plasma protein,
• cov metabolism thiab nthuav tawm: tsis yog metabolized, ua rau ntawm lub raum sai sai, T_1/2 yog los ntawm 5 txog 15 teev

Kev ntsuas rau siv

Raws li cov lus qhia, Lorist N tau pom zoo rau kev kho mob tawg hauv cov neeg mob uas pom tias yog kev sib xyaw ua ke.

Cov tshuaj no tseem tau sau tseg txhawm rau txo qis kev pheej hmoo ntawm cov hlab plawv thiab kev tuag ntawm cov neeg mob ntshav liab thiab sab laug ventricular hypertrophy.

Suav ne tus kws kho mob hais li cas txog kev kub siab

Kuv tau kho tus mob ntshav siab tau ntau xyoo. Raws li kev txheeb cais, nyob rau hauv 89% ntawm cov neeg mob, ntshav siab ua rau lub plawv nres lossis mob stroke thiab ib tus neeg tuag. Txog li ob feem peb ntawm cov neeg mob tam sim no tuag thaum thawj 5 xyoos ntawm tus kab mob.

Qhov tseeb hauv qab no - nws yog qhov ua tau thiab tsim nyog los daws lub siab, tab sis qhov no tsis kho tus kab mob nws tus kheej. Tsuas yog cov tshuaj uas tsis cuam tshuam lub hauv paus ntawm cov tshuaj suav thiab yog siv los ntawm cov kws kho plawv muaj npe rau kev kho mob ntshav siab yog Hyperten. Cov tshuaj cuam tshuam rau kev ua kom muaj tus kabmob, uas ua rau nws muaj peev xwm ua kom tiav ntawm kev kub siab. Ib qho ntxiv, nyob rau hauv tsoomfwv txoj haujlwm, txhua tus neeg nyob hauv Lavxias Lavxias tuaj yeem txais nws PUB DAWB .

Tshuaj Lorista N thiab Lorista ND muaj tib yam qhia rau siv:

• kev pheej hmoo txo kev mob plawv,
• txo kev tuag nyob hauv cov neeg mob mob laug ventricular hypertrophy thiab leeg ntshav siab,
• leeg ntshav siab (kev sib txuas ua ke).

Ob yam tshuaj yuav tsum tsis txhob siv rau cov teeb meem hauv qab no:

• anusia,
• xam phaj lactases,
• hyperkalemia,
• refractory hypokalemia,
• qias neeg lub raum lossis lub siab ua haujlwm,
• galactosemia,
• lub cev qhuav dej,
• arterial hypotension,
• cev xeeb tub
• piam thaj los yog galactose malabsorption syndrome,
• kev pub mis
• rhiab rau ib qho twg, rau sulfonamide derivatives,
• tsis tau muaj 18 xyoo.

Siv nrog ceev faj thaum:

• mob ntshav qab zib,
• ob leeg lub raum leeg txoj hlab ntsha,
• ua txhaum ntawm cov dej-electrolyte sib npaug ntawm cov ntshav (hypomagnesemia, hypochloremic alkalosis, tshuaj mob siab ntsws, hypokalemia),
• raum leeg mob hlwb,
• cov kab mob ntshav ntshav
• hyperuricemia,
• kev tsis haum keeb kwm
• hypercalcemia,
• mob gout,
• bronchial hawb pob,
• ib txhij nrog NSAIDs.

Cov kev mob tshwm sim tom qab no tuaj yeem los ntawm kev noj cov tshuaj no:

• kiv taub hau (tsis yog-qhov system thiab nruab nrog), insomnia, mob taub haumob taub hau, qaug zog,
• palpitations, koob-hais txog orthostatic hypotension, tachycardianyob rau hauv mob hnyav - vasculitis,
• hnoos, o ntawm lub qhov ntswg mob, pharyngitismob ua pa (sab saud),
• xeev siab, mob plab, zawv plabntuav dyspepsia, muaj qee zaus, kab mob siab, ua haujlwm nce siab rau daim siab ua haujlwm hauv lub siab, bilirubin, ua rau lub siab ua haujlwm tsis zoo,
• rov qab mob arthralgia,myalgia,
• Shenlein-Genoch liab doog, anemia,
• tsis muaj zog, mob hauv siab, astheniaperipheral edema,
• khaus, anaphylactic tshua, urticariaangioedema.

Noj cov tshuaj no tseem tuaj yeem cuam tshuam ntsuas ntsuas: hyperkalemia, ib qho kev nce ntawm creatinine, urea, nce ntxiv ntawm hematocrit thiab hemoglobin.

Cov lus qhia rau kev siv Lorista N (Txuj ci thiab ntau npaum li cas)

Cov tshuaj yog npaj rau hauv lub qhov ncauj. Tej zaum muaj kev sib xyaw nrog lwm cov tshuaj nrog cov nyhuv antihypertensive. Kev noj cov tshuaj tsis yog nyob ntawm kev noj zaub mov nkaus xwb.

Ntawm leeg ntshav siab qhov txhaj tshuaj tsawg kawg nkaus yog - 1 ntsiav tshuaj. Tom qab peb-lub limtiam kawm, qhov siab tshaj plaws kev ua haujlwm siab tiav. Txhawm rau kom muaj zog ntxiv, nws txaus los noj 2 ntsiav tshuaj ib hnub, uas yog qhov ntau tshaj plaws.

Rau cov neeg mob nrog txo bcc koj yuav tsum noj 25 mg losartan ib hnub. Yog tias qhov txo qis hauv BCC tshwm sim thaum noj cov tshuaj tseem ceeb ntawm diuretics, tom qab ntawd ua ntej pib kev kho mob nrog Lorista N, nws yog qhov tsim nyog kom thim kev noj haus ntawm diuretics.

Thawj qhov muab tshuaj tsis xav kom raug kho rau cov neeg mob uas ntawm lim ntshav kev txom nyem lub raum tsis ua hauj lwm (muaj pes tsawg) thiab cov neeg laus laus(tshaj 65 xyoos).

Cov koob tshuaj txhua hnub ntawm 50 mg ntawm losartan tau sau tseg los txo cov kev pheej hmoo ntawm cov hlab plawv thiab kev tuag ntawm cov neeg mob uas tau txheeb xyuas nrog sab laug ventricular hypertrophy lossis hlab ntsha tawg. Yog tias nws tsis tuaj yeem txo qhov siab thaum noj 50 mg, tom qab ntawd koj yuav tsum sib xyaw losartan nrog hydrochlorothiazide (12.5 mg). Yog tias tsim nyog, losartan tuaj yeem nce txog 100 mg tsis tas hloov cov koob tshuaj hydrochlorothiazide. Qhov siab tshaj txhua hnub qhov noj tshuaj yuav tsum tsis pub ntau tshaj ib zaug 2 ntsiav tshuaj.

Cov lus qhia rau kev siv Lorista ND: cov tshuaj no tau sau tseg nyob rau qhov tsis muaj kev kho tshuaj los ntawm kev noj tshuaj Lorista N. Cov tshuaj Lorista ND noj nyob rau tib hnub tshuaj zoo li Lorista N.

Noj ntau dhau losartan muaj cov tsos mob nram qab no: qhov txo qis hauv lub siab, bradycardia, tachycardiaCov. Yog tias pom tias muaj ntau tus tsos mob tshwm sim, kev kho mob raug pom zoo: kev kho cov tsos mob, yuam kom diuresis. Hemodialysis nyob rau hauv cov ntaub ntawv no yog qhov ua tsis tiav.

Nyob rau hauv cov ntaub ntawv ntawm overdose hydrochlorothiazide Cov tsos mob yuav tshwm sim: tshuaj tiv thaiv hypochloremia, hypokalemia, tshuaj mob siab ntswsCov. Hauv qhov no, kev kho cov tsos mob yog tau sau tseg.

Clinically tseem ceeb sib cuam tshuam ntawm losartan nrog digoxin, phenobarbital, hydrochlorothiazide, ketoconazolomvarfarin, erythromycin thiab cimetidine tsis qhia npe.

Cov qib ntawm cov khoom noj ua kom lub cev ntuag tsawg zuj zus thaum noj cov tshuaj losartan nrog rabampicin thiab fluconazoleCov. Txawm li cas los xij, xws li kev cuam tshuam tsis tau tshawb fawb txog kev tshawb fawb.

Hyperkalemia tej zaum yuav yog los ntawm kev sib txuas nrog cov tshuaj tua poov tshuaj-tshuaj tua kab mob (triamteren, Nrogpironolactone, amiloride), cov ntsev ntsev tshuaj ntsev lossis cov tshuaj ntxiv poov tshuaj.

Qhov ua tau zoo ntawm losartan tej zaum yuav txo qis vim kev noj NSAIDs thiab xaiv COX-2 inhibitors.

Txais tos indomethacin tej zaum yuav ua rau qhov txo qis hauv qhov hypotensive lazortana.

Ethanol, Cov tshuaj yeeb thiab barbiturates thaum ua ke nrog hydrochlorothiazide, lawv tuaj yeem ua rau orthostatic hypotension.

Kev saws ua ib txhij cov kab mob hypoglycemic (suav nrog tshuaj insulin) tej zaum yuav tau kho kom haum.

Ib qho kev tiv thaiv ntxiv yuav tshwm sim thaum sib txuas nrog kev kho mob nrog lwm tus antihypertensive cov neeg sawv cev.

Cuam tshuam kev nqus ntawm hydrochlorothiazide tuaj yeem siv yeeb tshuaj xws li colestipol lossis colestyramine.

Hydrochlorothiazide tej zaum yuav txhim kho cov hauj lwm zoo ntawm cov leeg relaxants (tudocurarin).

Cov natriuretic, hypotensive, thiab diuretic los ntawm hydrochlorothiazide tuaj yeem txo qis vim kev siv ntawm NSAIDs(suav nrog COX-2 inhibitors).

Kev kuaj pom ntawm parathyroid muaj nuj nqi tuaj yeem tsis txawv txav vim muaj cov txiaj ntsig ntawm hydrochlorothiazide ntawm calcium metabolism.

Cov khw muag tshuaj yog muag tshwj xeeb nrog cov tshuaj xaj.

Cov tshuaj yuav tsum tau muab khaws cia hauv qhov chaw tsaus, tsis ntub. Qhov sov siab tshaj plaws yog 30 ° C.

Muaj peev xwm ua ke nrog lwm cov tshuaj tiv thaiv antihypertensive.

Cov tshuaj thawj zaug rau cov neeg mob laus tsis hloov kho tshwj xeeb.

Hydrochlorothiazide tuaj yeem nce ntxiv arterial hypotension thiab tawg dej-electrolyte tshuav nyiaj li casCov. Nws kuj tseem muaj peev xwm ua rau cov ntshav qabzib tsis txaus, txo qis tso zis tawm ntawm cov calcium, uas ua rau cov ntshav calcium muaj ntau ntxiv.

Noj cov tshuaj ntawm II lossis III peb lub hlis thaum cev xeeb tub tuaj yeem ua rau me nyuam tuag. Cov tshuaj yuav tsum tsis ua ntxiv yog tias cev xeeb tub tshwm sim. Tus menyuam mos lossis menyuam hauv plab yuav tshwm sim dajntooniam thrombocytopenia.

Kev noj cov tshuaj hauv cov neeg mob feem ntau tsis cuam tshuam lub peev xwm los ua cov haujlwm uas yuav tsum muaj kev kub siab. Txawm li cas los xij, qee tus neeg mob thaum pib kho yuav soj ntsuam qhov txo qis hauv lub siab, kiv taub hau. Ua ntej pib txoj haujlwm ntawd, nws yog qhov yuav tsum tau soj ntsuam tus mob tom qab noj cov tshuaj.

Rau analogues Lorista N suav nrog: angizar ntxiv rau, gizaar forte, co-center, Lozap Ntxiv, kaw, nostasartan n, tozaar-g.

Tag nrho cov ntsuas saum toj no kuj siv rau cov txhais tau tias ntawm Lorista ND.

Qhov nruab nrab tshuaj tau yog 4.5 cov qhab nia (tawm ntawm 5). Cov neeg yuav khoom nco ntsoov qhov ua tau zoo ntawm cov tshuaj, nws cov nyhuv tsawg. Ntawm qhov tsis txaus ntseeg yog qhov yuav tsum tau noj txhua txhua hnub thiab ua kom pom kev phiv.

Cov lus pom zoo los ntawm cov kws kho mob hais txog cov tshuaj hais tias nws cov hauj lwm zoo. Txawm li cas los xij, cov kws tshaj lij tau sau tseg tias nws yuav tsum tau coj nws nruj ntawm cov koob tshuaj uas txiav txim los ntawm tus kws kho mob txhawm rau txhawm rau txo kev phom sij ntawm kev phiv.

Xyuas rau Lorist ND phim xyuas txog Loriste N.

Nqi Lorists ND nyob rau hauv Russia nws qhov nruab nrab 350 rubles, hauv Ukraine - 112 UAH.

Tus nqi nruab nrab rau Lorist N nyob rau hauv Russia - 214 rubles, hauv Ukraine - 114 UAH.

THEM SAIB!
Cov ntaub ntawv hais txog cov tshuaj ntawm lub xaib yog kev saib xyuas-dav dav, sau los ntawm pej xeem cov chaw thiab tsis tuaj yeem ua lub hauv paus rau kev txiav txim siab txog kev siv tshuaj thaum lub sijhawm kho mob. Ua ntej siv cov tshuaj Lorista N / ND, nco ntsoov sab laj nrog koj tus kws kho mob.

Kos ntsiab lus xaus

Kev mob plawv thiab mob nkees yog qhov ua rau kwv yees li 70% ntawm tag nrho cov neeg tuag hauv ntiaj teb. Xya tawm ntawm kaum tus neeg tuag vim kev txhaws ntawm cov hlab ntsha ntawm lub plawv lossis paj hlwb.

Qhov tshwj xeeb tshaj yog txaus ntshai yog qhov tseeb tias ntau tus neeg tsis txawm xav tias lawv muaj ntshav siab. Thiab lawv tsis muaj sijhawm los kho qee yam, tsuas yog dooming lawv tus kheej kom tuag.

• Mob taub hau
• Lub plawv palpitations
• Dub tsuas me me pem hauv ntej lub qhov muag (yoov)
• Apathy, txob taus, tsis tsaug zog
• Qhov muag plooj
• Tawm hws
• Ntev heev ua rog
• Teb lub ntsej muag
• Ntsej muag thiab ua daus no ntawm cov ntiv tes
• Siab surges

Txawm tias ib qho ntawm cov tsos mob no yuav tsum ua rau koj xav. Thiab yog tias muaj ob, ces tsis txhob yig - koj muaj kub siab.

Yuav kho cov ntshav siab thaum lub sij hawm muaj tshuaj ntau uas raug nqi ntau?

Feem ntau cov tshuaj yuav tsis ua ib qho zoo, thiab qee qhov tseem tuaj yeem tsim kev puas tsuaj! Lub sijhawm no, tsuas yog cov tshuaj nkaus xwb uas tau pom zoo los ntawm Ministry of Health rau kev kho mob tawg yog Hyperten.

Mus txog Lub Ob Hlis 26th. Lub koom haum ntawm Cardiology, ua ke nrog Ministry of Health, yog ua ib qho program " tsis muaj kub siab"Nyob rau hauv uas Hyperten muaj PUB DAWB , txhua tus neeg nyob hauv nroog thiab thaj chaw!

Zoo, kuv tsis paub yuav ua li cas, rau kuv, feem ntau cov tshuaj yog cov khib nyiab tiav, kev siv nyiaj pov tseg.Koj puas paub ntau npaum li cas Kuv twb sim txhua yam .. Tsuas yog Hyperten ib txwm pab (los ntawm txoj kev, raws li qhov kev pabcuam tshwjxeeb koj tuaj yeem tau yuav luag txhua yam dawb). Kuv haus nws rau 4 lub lis piam, tom qab thawj lub lim tiam ntawm kev noj, kuv kev noj qab haus huv zoo tuaj. 4 lub hlis dhau mus txij li ntawd, qhov kev kub siab yog qhov qub, thiab kuv tsis nco qab txog kub siab! Txhais tau tias qee zaum kuv haus dua 2-3 hnub, tsuas yog rau kev tiv thaiv. Thiab kuv tau kawm txog nws zoo rau nws los ntawm kev sib tsoo, los ntawm cov ntawv no ..

Lorista N / N

Kev piav qhia cuam tshuam rau 07.05.2014

• Lub npe Latin: Lorista H, Lorista HD
• ATX Code: C09DA01
• Yam tshuaj muaj sia: Losartan, Hydrochlorothiazide (Hydrochlorothiaz>

Hauv ib ntsiav tshuaj ntawm cov tshuaj Lorista N muaj:

• 50 mg losartan poov tshuaj,
• 12,5 mg hydrochlorothiazide,
• magnesium stearate, MCC, lactose monohydrate, pregelatinized hmoov txhuv nplej siab.

Cov tshuaj ntsiav tshuaj Lorista ND ntim:

• 100 mg losartan poov tshuaj,
• 25 mg nidrohlortiziada,
• magnesium stearate, MCC, lactose monohydrate, pregelatinized hmoov txhuv nplej siab.

Lub plhaub muaj hypromellosequinoline zas (daj), talc, macrogol 4000 thiab titanium dioxide (E171).

Cov Yuav Tsum Muaj

Ob yam tshuaj yuav tsum tsis txhob siv rau cov teeb meem hauv qab no:

• anusia,
• xam phaj lactases,
• hyperkalemia,
• refractory hypokalemia,
• qias neeg lub raum lossis lub siab ua haujlwm,
• galactosemia,
• lub cev qhuav dej,
• arterial hypotension,
• cev xeeb tub
• piam thaj los yog galactose malabsorption syndrome,
• kev pub mis
• rhiab rau ib qho twg, rau sulfonamide derivatives,
• tsis tau muaj 18 xyoo.

Siv nrog ceev faj thaum:

• mob ntshav qab zib,
• ob leeg lub raum leeg txoj hlab ntsha,
• ua txhaum ntawm cov dej-electrolyte sib npaug ntawm cov ntshav (hypomagnesemia, hypochloremic alkalosis, tshuaj mob siab ntsws, hypokalemia),
• raum leeg mob hlwb,
• cov kab mob ntshav ntshav
• hyperuricemia,
• kev tsis haum keeb kwm
• hypercalcemia,
• mob gout,
• bronchial hawb pob,
• ib txhij nrog NSAIDs.

Sab sij huam

Cov kev mob tshwm sim tom qab no tuaj yeem los ntawm kev noj cov tshuaj no:

• kiv taub hau (tsis yog-qhov system thiab nruab nrog), insomnia, mob taub haumob taub hau, qaug zog,
• palpitations, koob-hais txog orthostatic hypotension, tachycardianyob rau hauv mob hnyav - vasculitis,
• hnoos, o ntawm lub qhov ntswg mob, pharyngitismob ua pa (sab saud),
• xeev siab, mob plab, zawv plabntuav dyspepsia, muaj qee zaus, kab mob siab, ua haujlwm nce siab rau daim siab ua haujlwm hauv lub siab, bilirubin, ua rau lub siab ua haujlwm tsis zoo,
• rov qab mob arthralgia,myalgia,
• Shenlein-Genoch liab doog, anemia,
• tsis muaj zog, mob hauv siab, astheniaperipheral edema,
• khaus, anaphylactic tshua, urticariaangioedema.

Noj cov tshuaj no tseem tuaj yeem cuam tshuam ntsuas ntsuas: hyperkalemia, ib qho kev nce ntawm creatinine, urea, nce ntxiv ntawm hematocrit thiab hemoglobin.

Noj ntau dhau

Noj ntau dhau losartan muaj cov tsos mob nram qab no: qhov txo qis hauv lub siab, bradycardia, tachycardiaCov. Yog tias pom tias muaj ntau tus tsos mob tshwm sim, kev kho mob raug pom zoo: kev kho cov tsos mob, yuam kom diuresis. Hemodialysis nyob rau hauv cov ntaub ntawv no yog qhov ua tsis tiav.

Nyob rau hauv cov ntaub ntawv ntawm overdose hydrochlorothiazide Cov tsos mob yuav tshwm sim: tshuaj tiv thaiv hypochloremia, hypokalemia, tshuaj mob siab ntswsCov. Hauv qhov no, kev kho cov tsos mob yog tau sau tseg.

Kev sib txuam

Clinically tseem ceeb sib cuam tshuam ntawm losartan nrog digoxin, phenobarbital, hydrochlorothiazide, ketoconazolomvarfarin, erythromycin thiab cimetidine tsis qhia npe.

Cov qib ntawm cov khoom noj ua kom lub cev ntuag tsawg zuj zus thaum noj cov tshuaj losartan nrog rabampicin thiab fluconazoleCov. Txawm li cas los xij, xws li kev cuam tshuam tsis tau tshawb fawb txog kev tshawb fawb.

Hyperkalemia tej zaum yuav yog los ntawm kev sib txuas nrog cov tshuaj tua poov tshuaj-tshuaj tua kab mob (triamteren, Nrogpironolactone, amiloride), cov ntsev ntsev tshuaj ntsev lossis cov tshuaj ntxiv poov tshuaj.

Qhov ua tau zoo ntawm losartan tej zaum yuav txo qis vim kev noj NSAIDs thiab xaiv COX-2 inhibitors.

Txais tos indomethacin tej zaum yuav ua rau qhov txo qis hauv qhov hypotensive lazortana.

Ethanol, Cov tshuaj yeeb thiab barbiturates thaum ua ke nrog hydrochlorothiazide, lawv tuaj yeem ua rau orthostatic hypotension.

Kev saws ua ib txhij cov kab mob hypoglycemic (suav nrog tshuaj insulin) tej zaum yuav tau kho kom haum.

Ib qho kev tiv thaiv ntxiv yuav tshwm sim thaum sib txuas nrog kev kho mob nrog lwm tus antihypertensive cov neeg sawv cev.

Cuam tshuam kev nqus ntawm hydrochlorothiazide tuaj yeem siv yeeb tshuaj xws li colestipol lossis colestyramine.

Hydrochlorothiazide tej zaum yuav txhim kho cov hauj lwm zoo ntawm cov leeg relaxants (tudocurarin).

Cov natriuretic, hypotensive, thiab diuretic los ntawm hydrochlorothiazide tuaj yeem txo qis vim kev siv ntawm NSAIDs(suav nrog COX-2 inhibitors).

Kev kuaj pom ntawm parathyroid muaj nuj nqi tuaj yeem tsis txawv txav vim muaj cov txiaj ntsig ntawm hydrochlorothiazide ntawm calcium metabolism.

Cov lus qhia tshwj xeeb

Muaj peev xwm ua ke nrog lwm cov tshuaj tiv thaiv antihypertensive.

Cov tshuaj thawj zaug rau cov neeg mob laus tsis hloov kho tshwj xeeb.

Hydrochlorothiazide tuaj yeem nce ntxiv arterial hypotension thiab tawg dej-electrolyte tshuav nyiaj li casCov. Nws kuj tseem muaj peev xwm ua rau cov ntshav qabzib tsis txaus, txo qis tso zis tawm ntawm cov calcium, uas ua rau cov ntshav calcium muaj ntau ntxiv.

Noj cov tshuaj ntawm II lossis III peb lub hlis thaum cev xeeb tub tuaj yeem ua rau me nyuam tuag. Cov tshuaj yuav tsum tsis ua ntxiv yog tias cev xeeb tub tshwm sim. Tus menyuam mos lossis menyuam hauv plab yuav tshwm sim dajntooniam thrombocytopenia.

Kev noj cov tshuaj hauv cov neeg mob feem ntau tsis cuam tshuam lub peev xwm los ua cov haujlwm uas yuav tsum muaj kev kub siab. Txawm li cas los xij, qee tus neeg mob thaum pib kho yuav soj ntsuam qhov txo qis hauv lub siab, kiv taub hau. Ua ntej pib txoj haujlwm ntawd, nws yog qhov yuav tsum tau soj ntsuam tus mob tom qab noj cov tshuaj.

Rau analogues Lorista N suav nrog: angizar ntxiv rau, gizaar forte,co-center, Lozap Ntxiv, kaw, nostasartan n, tozaar-g.

Tag nrho cov ntsuas saum toj no kuj siv rau cov txhais tau tias ntawm Lorista ND.

Kev txheeb xyuas txog Lorista N

Qhov nruab nrab tshuaj tau yog 4.5 cov qhab nia (tawm ntawm 5). Cov neeg yuav khoom nco ntsoov qhov ua tau zoo ntawm cov tshuaj, nws cov nyhuv tsawg. Ntawm qhov tsis txaus ntseeg yog qhov yuav tsum tau noj txhua txhua hnub thiab ua kom pom kev phiv.

Cov lus pom zoo los ntawm cov kws kho mob hais txog cov tshuaj hais tias nws cov hauj lwm zoo. Txawm li cas los xij, cov kws tshaj lij tau sau tseg tias nws yuav tsum tau coj nws nruj ntawm cov koob tshuaj uas txiav txim los ntawm tus kws kho mob txhawm rau txhawm rau txo kev phom sij ntawm kev phiv.

Xyuas rau Lorist ND phim xyuas txog Loriste N.

Qhov sib txawv ntawm Lorista thiab Lorista N yog dab tsi?

Qhov sib txawv tseem ceeb ntawm ob lub tshuab kho mob no nyob rau hauv lawv muaj pes tsawg leegCov. Yog li, yog tias nyob rau hauv ib qho dog dig version ntawm cov tshuaj no, losartan yog muab, thiab cellulose, pob kws hmoov txhuv nplej siab, magnesium stearate, silicon dioxide thiab li ntawm tau siv ua kev zam, yog li ntawm Lorista N, txhua qhov saum toj no kuj tau ntxiv nrog hydrochlorothiazide. Qhov tom kawg yog cov tshuaj uas txo qhov kev rov ua dua tshiab ntawm Na + ntawm qib ntawm cortical ntu. Tau kawg, nws cov nyhuv poob qis, thiab qee zaus txawm tias nres yog qhov glomerular pom kev poob qis rau 30 ml / min.

Yog tias peb tham txog cov neeg mob ntshav qab zib insipidus, ces cov cuab yeej no yuav muab rau lawv antidiuretic nyhuvtsim nyog nyob rau hauv kev txiav txim kom txo tau qhov ntim ntawm cov zis, nrog rau nce nws cov concentration. Hauv kev siv yeeb tshuaj "LoristaN", qee cov lus qhia tshwj xeeb tau muab. Qhov tshwj xeeb tshaj plaws ntawm lawv yog qhov tsis muaj qhov xav tau los xaiv qhov pib txhaj tshuaj rau cov neeg laus. Ntxiv mus, ua ntej koj yuav Lorista N, koj yuav tsum coj mus rau hauv tus account qhov tseeb tias nws tseem muaj cov lactose, uas tsis tuaj yeem raug cuam tshuam txog cov neeg mob uas tau pom yav dhau los galactosemia.

Txhawm rau saib lub ntsab lug saum toj saud, peb xav txog nws tsim nyog sau tseg qee yam, tshwj xeeb qhov tseem ceeb:

1. Firstly, cov tshuaj sib txawv ntawm lawv cov paj hlwb. Yog li, piv txwv, nyob rau hauv rooj plaub ntawm Lorista N, ib qho kev tivthaiv xws li hydrochlorothiazide yog muab. Hauv txoj ntsiab cai, nws lub xub ntiag ntxiv cov txiaj ntsig rau cov tshuaj no vim tias nws txo Na + reabsorption.
2. Tus nqi ntawm ob hom tshuaj no kuj tseem txawv. Yog li, hauv qhov xwm txheej uas rau tus qauv Lorista, koj yuav tsum tau muab 130 rubles, tom qab ntawd rau kev yuav khoom ntawm Lorista N, koj yuav tsum tau muab 230 rubles.

Muaj pes tsawg leeg thiab pharmacological kev txiav txim siab

Cov tshuaj yog mus rau cov pab pawg ntawm cov tshuaj tiv thaiv antihypertensive. Nws cov khoom tseem ceeb yog losartan. Cov tshuaj no txhawb cov kev ua si renin thiab txo cov aldosterone ntau. Qhov no pab txo cov kev ntxhov siab ntawm phab ntsa ntawm cov hlab ntsha thiab lub plawv.

Ntxiv rau losartan, cov tshuaj muaj pes tsawg leeg suav nrog:

• cellulose
• magnesium stereate,
• cellulose
• hypromellose,
• hmoov txhuv nplej siab
• talcum hmoov
• silica
• hypromellose,
• titanium dioxide
• propylene glycol.

Qhov nquag ua haujlwm yog yooj yim nqus, ua li cas hauv lub zom zaub mov, nws kev nthuav tawm yog nqa los ntawm lub raum. Ib feem, nws tawm hauv lub cev nrog bile.

Yuav ua li cas Lorista thiab Lorista N tshuaj ua haujlwm?

Lorista belongs rau cov pab pawg ntawm cov angiotensin II receptor antagonists.

Lorista belongs rau cov pab pawg ntawm cov angiotensin II receptor antagonists.

Lub zog tshuaj ntawm cov tshuaj yog poov tshuaj losartan. Cov neeg tsim khoom muab 4 tshuaj:

Cov tshuaj no xaiv tau txwv tsis pub AT1 receptors, yam tsis muaj kev cuam tshuam cov receptors ntawm lwm cov tshuaj hormones koom nrog kev tswj hwm hauv lub xeev vascular system. Vim qhov no, cov tshuaj inhibits qhov nce ntawm systolic thiab diastolic ntshav siab tshwm sim los ntawm infusion ntawm angiotensin:

• 85% thaum lub sijhawm siab tshaj plaws plasma concentration tau mus txog ib teev tom qab noj 100 koob tshuaj,
• 26-39% tom qab 24 teev txij li lub sijhawm kev tswj hwm.

Ntxiv rau ntawm kev mob ntshav hauv arterial hypertension, kev qhia rau kev siv cov tshuaj no yog:

• mob plawv tsis ua hauj lwm (yog tias kho nrog ACE inhibitors tsis tau),
• qhov xav tau kom qeeb qhov muaj mob ntawm lub raum tsis ua haujlwm hauv cov neeg mob uas muaj ntshav qab zib hom 2.

Noj cov tshuaj no rau ntshav siab tuaj yeem txo kev ploj tuag.
Lorista yog siv rau kev mob ntshav txhaws.
Lorista yog siv rau kev mob plawv ntev.
Noj cov tshuaj no rau ntshav siab tuaj yeem txo kev tuag los ntawm kev mob plawv.
Lorista siv thaum tsim nyog yuav ua rau qeeb tus mob ntawm lub raum tsis ua haujlwm rau cov neeg mob ntshav qab zib hom 2.

Noj cov tshuaj no rau kev kub siab tuaj yeem txo kev tuag los ntawm kev mob plawv lossis mob hlab ntsha tawg ntawm cov neeg mob uas mob plawv, tshwj xeeb sab laug ventricular hypertrophy.

Cov tshuaj hauv cov tshuaj Lorista N suav nrog:

• hydrochlorothiazide - 12,5 mg,
• poov tshuaj losartan - 50 mg.

Nws yog cov tshuaj antihypertensive tshuaj.

Kev siv cov khoom sib txuas ua ke no ua rau cov nyhuv tawm ntau dua li siv cais.

Hydrochlorothiazide belongs rau cov pab pawg ntawm thiazide diuretics, muaj cov nyhuv hauv qab no:

• nce kev ua si ntawm renin thiab cov ntsiab lus ntawm angiotesin II hauv ntshav ntshav,
• txhawb kev tso tawm ntawm aldosterone,
• txo qis reabsorption ntawm sodium thiab cov poov tshuaj nyob hauv cov ntshav ntshav.

Cov tshuaj sib xyaw ua ke no muab cov ntshav siab txo qis, tsis cuam tshuam rau lub plawv dhia.

Cov tshuaj sib xyaw ua ke no muab cov ntshav siab txo qis, tsis cuam tshuam rau lub plawv dhia.

Kev kho mob ntawm cov koob tshuaj tshwm sim 2 teev tom qab kev tswj hwm thiab kav rau 24 teev.

Cov tshuaj muaj feem muaj cov kev mob tshwm sim ntau, ntawm lawv:

• kev cuam tshuam ntawm cov hlab ntsha paj hlwb: pw tsis txaus, mob taub hau, nco qab tsis zoo, thiab lwm yam,
• lub siab tuaj cuam tshuam tuaj
• Lub raum khiav tsis zoo (suav nrog mob raum tsis ua haujlwm),
• kev ntxhov siab hauv cov dej-electrolyte metabolism,
• ntxiv cov roj (cholesterol) thiab triglycerides,
• Cov tsos mob dyspeptic
• ntau yam qhia ntawm ua xua,
• pom kev mob thiab qhov muag tsis zoo,
• hnoos thiab mob ntswg ib ce,
• ua txhaum kev sib deev.

Cov tshuaj hauv cov lus nug muaj ntau qhov tshwm sim, ntawm lawv pw tsaug zog.
Cov tshuaj hauv cov lus nug muaj ntau qhov tshwm sim, ntawm lawv muaj kev tsis haum tshuaj.
Cov tshuaj nyob rau hauv nqe lus nug muaj ntau ntawm cov kev mob tshwm sim, ntawm lawv muaj kev ua haujlwm tsis zoo hauv lub raum.
Cov tshuaj hauv cov lus nug muaj ntau qhov tshwm sim, ntawm lawv tau ua txhaum ntawm lub plawv lub plawv.
Cov tshuaj suav tshuaj muaj ntau cov kev mob tshwm sim, ntawm lawv dyspeptic cuam tshuam.
Cov tshuaj noj xam pom tias muaj ntau cov kev mob tshwm sim, ntawm lawv cov pom mob.
Cov tshuaj siv hauv cov lus nug muaj ntau ntau tshwm sim, suav nrog kev hnoos.

Vim tias qhov tseeb tias kev noj tshuaj uas muaj hydrochlorothiazide tuaj yeem ua rau lub raum tsis ua haujlwm, lawv yuav tsum tau ua ke nrog Metformin nrog kev ceev faj. Qhov no tuaj yeem ua rau kev txhim kho ntawm cov kab mob lactic acidosis.

Koj yuav tsum paub tias cov tshuaj no tau sib kis hauv cov neeg mob hnub nyoog qis dua 18 xyoo, thaum cev xeeb tub thiab lactation, nrog rau cov kab mob hauv qab no:

• hypotension
• hyperkalemia
• lub cev qhuav dej
• malabsorption ntawm qabzib.

Cov tshuaj tau noj qhov ncauj 1 teev nyob rau ib hnub / hnub, tsis hais los ntawm cov zaub mov. Cov ntsiav tshuaj yuav tsum tau muab ntxuav nrog kua kom ntau. Kev sib xyaw ntawm cov tshuaj no nrog lwm cov tshuaj tiv thaiv kev tiv thaiv tuaj yeem siv tau. Nrog kev siv tib txhij, ib qho ntxiv cov nyhuv yog pom.

Kev Sib piv Cov Tshuaj

Txawm hais tias muaj ntau ntawm cov yam ntxwv uas sib xyaw ua ke siv cov tshuaj no, tsuas yog tus kws kho mob tuaj yeem txiav txim siab yuav xaiv qhov kev kho twg, nyob ntawm tus neeg mob cov kev xav tau. Nws tsis tuaj yeem yuav tsum tau hloov ib qho tshuaj nrog lwm tus ntawm nws tus kheej.

Cov tshuaj no yog contraindicated hauv hypotension.
Cov tshuaj no yog contraindicated hauv hyperkalemia.
Cov tshuaj no yog contraindicated hauv lub cev qhuav dej.
Cov tshuaj no yog contraindicated thaum cev xeeb tub.
Cov tshuaj no yog contraindicated thaum lactation.
Cov tshuaj no yog contraindicated rau hauv cov neeg mob hnub nyoog qis dua 18 xyoo.

Cov tshuaj no muaj cov yam ntxwv zoo li hauv qab no:

• qhov tshwm sim tiav los ntawm kev noj tshuaj yog txo qis ntshav siab,
• muaj cov poov tshuaj nyob rau hauv losartan,
• daim ntawv tso tawm tshuaj.

Dab tsi yog qhov txawv

Lub ntsiab sib txawv ntawm cov tshuaj yog pom thaum muab piv rau cov kwv yees. Nws dag nyob rau hauv muaj Lorist N ntawm ib qho ntxiv cov tshuaj nquag. Qhov tseeb no tau xav txog qhov xwm ntawm kev txiav txim ntawm cov tshuaj (ntxiv cov nyhuv diuretic), thiab nws tus nqi. Ib qho tseem ceeb yog qhov tseeb tias tshuaj muaj 4 ntau npaum li cas.

Lorista N, tsis zoo li Lorista, tsis yog siv los kho lub plawv tsis ua hauj lwm thiab qeeb kev loj hlob ntawm lub raum ua rau cov neeg mob ntshav qab zib.

Uas yog pheej yig dua

Tus nqi ntawm cov tshuaj Lorista yog feem ntau nyob ntawm qhov ntau ntawm cov tshuaj nquag. Lub vev xaib ntawm cov chaw muag tshuaj nrov Lavxias muaj 30 ntsiav tshuaj ntawm cov nqi hauv qab no:

• 12,5 mg - 145.6 rubles,
• 25 mg - 159 rubles,
• 50 mg - 169 rubles,
• 100 mg - 302 rub.

Thaum tus nqi ntawm Lorista N yog 265 rubles. Los ntawm qhov no tuaj yeem pom tau tias nrog kev sib txig sib luag ntawm losartan potassium, kev npaj ua ke yuav raug nqi ntau dua vim tias muaj ib qho tshuaj ntxiv nyob hauv cov muaj pes tsawg leeg.

Nws yog qhov zoo dua - Lorista lossis Lorista N

Lorista muaj ib tug xov tooj ntawm cov tsis meej qhov zoo tshaj daim ntawv ua ke:

• lub peev xwm los muab tshuaj ntau dua yooj yim,
• tsawg dua cov kev mob tshwm sim vim los ntawm tsuas yog ib qho kev nquag ua,
• qis tus nqi.

Txawm li cas los xij, qhov no tsis txhais tau tias kev nyiam xaiv yuav tsum tau muab rau daim ntawv no ntawm cov tshuaj. Yog hais tias tus neeg mob lub xeev ntawm kev noj qab haus huv yuav tsum muaj kev sib xyaw ua ke, kev teem sij hawm ntawm Lorista N yuav muaj kev txaus siab tag nrho.

Lorista - tshuaj rau qhov txo qis

Kev tshuaj xyuas ntawm cov kws kho mob txog Lorista thiab Lorista N

Alexander, 38 xyoo, kws kho plawv, Moscow: "Kuv xav txog Lorista tam sim no cov tshuaj, zoo rau kev siv hauv kev kub siab ntawm I thiab II degrees."

Elizaveta, 42, kws kho plawv, Novosibirsk: "Kuv xav tias losartan poov tshuaj tsis ua hauj lwm zoo rau kev kho mob ntshav qab zib. Kuv ib txwm xaj nws ua ke nrog calcium antagonists lossis diuretics. Hauv kuv kev coj ua, kuv feem ntau siv cov tshuaj sib xyaw ua ke Lorista N".

Kev Ntsuam Xyuas Rau Neeg Mob

Azat, 54 xyoo, Ufa: "Kuv tau noj Lorista thaum sawv ntxov rau ib hlis. Qhov kev kho mob siv sij hawm tag nrho ib hnub. Thiab txawm tias tag kis sawv ntxov, ua ntej noj cov ntsiav tshuaj, lub siab tseem nyob hauv qhov lees paub."

Marina, 50 xyoo, Kazan: “Kuv xav txog Lorista N ua qhov txiaj ntsig zoo tshaj plaws uas cov hydrochlorothiazide muaj nyob hauv nws cov nkauj, los ntawm kev hle kom zoo, tsis ua rau kom tso zis heev dua.”

Vladislav, hnub nyoog 60 xyoo, St. Petersburg: "Kuv coj Lorista tau ntau xyoo, tab sis sijhawm dhau sijhawm kuv tau pib pom tias thaum yav tsaus ntuj lub siab twb dhau qhov qub. Tus kws kho mob pom zoo hloov cov tshuaj."

Thaum cev xeeb tub thiab lactation

Cov yam ntxwv ntawm cov nyhuv ntawm losartan ntawm kev xeeb tub thiab menyuam kev loj hlob tsis tau kawm. Yog li, thaum cev xeeb tub, cov tshuaj yuav tsum tau cuam tshuam. Cov tshuaj muaj peev xwm cuam tshuam tsis zoo rau lub mis, yog li koj yuav tsum tsis txhob siv nws thaum pub niam mis.

Nkag tau cov neeg mob Lorista uas muaj hnub nyoog qis dua yuav raug txwv, vim tias cov ntaub ntawv hais txog nws txoj kev nyab xeeb thiab siv tau rau lawv tsis muaj.

Sab sij huam

Cov tshuaj no zoo tiv thaiv thiab tsis tshua muaj kev phiv tshuaj. Tab sis tib neeg cov kab mob sib txawv, yog li cov tshuaj tiv thaiv losartan tuaj yeem sib txawv. Hauv daim ntawv teev cov kev mob tshwm sim hais txog:

• kiv taub hau
• mob taub hau
• insomnia
• tachycardia
• hnoos
• o ntawm cov qog ua kua,
• xeev siab
• mob plab
• txo qis libido
• myalgia
• anemia
• nce hws
• daim tawv nqaij ua pob,
• khaus
• urticaria.

Tab sis qee zaum yuav tsum thim tawm cov tshuaj ntawd. Yog li, lawv qhov tshwm sim yuav tsum tshaj tawm rau tus kws kho mob uas koom nrog.

Cov lus thiab cov xwm txheej ntawm kev cia

Rau qhov no, kev cuam tshuam ntawm tshav ntuj yog qhov txaus ntshai, yog li ntawd nws raug nquahu kom muab nws tso rau hauv qhov chaw tsaus. Nws kuj tseem tsis tuaj yeem nqa dej rau nws - qhov no cuam tshuam lub sijhawm sib xws thiab thaj chaw muaj tshuaj. Qhov zoo tshaj qhov kub cia yog txog 30 degrees. Nws yog qhov tsim nyog kom ua cov tshuaj no rau cov menyuam yaus siv tsis tau.

Lorista tseem siv tau nyob rau 5 xyoos (yog tias kev cia khoom tsim nyog). Tom qab no, cov tshuaj txwv tsis pub.

Zoo sib xws txhais tau tias

Muaj ntau cov tshuaj uas tuaj yeem hloov cov tshuaj no. Cov no suav nrog:

Tus kws kho mob yuav tsum xaiv yam uas haum rau tus neeg mob. Txhua yam ntawm cov txhais tau tias nws muaj nws tus yam ntxwv, vim tias qhov ntawd tuaj yeem tuaj yeem tsim kev puas tsuaj.

Tus neeg mob lub tswv yim

Raws li cov neeg siv tshuaj xyuas, koj tuaj yeem nkag siab txog yam tshwm sim tuaj yeem xav los ntawm cov tshuaj Lorista.

Kuv lub siab pib nce tsis ntev los no, thiab Lorista yog thawj yam tshuaj uas kuv tus kws kho mob tau sau tseg. Txog tam sim no, Kuv tsis tuaj yeem hais ib qho tsis zoo txog nws. Muaj mob taub hau thaum xub thawj, tab sis kws kho mob tau hais tias lub cev no teb rau cov kev hloov. Tom qab ntawd txhua yam mus, thiab kuv pib zoo siab dua. Lub siab poob qis yuav luag txhua qhov, thiab lub siab ntawm nkees tas li thiab qaug zog kuj ploj mus.

Valentina, hnub nyoog 43 xyoos

Kuv muaj teeb meem nrog lub siab ntau xyoo dhau los, yog li kuv tswj tau hloov ntau cov tshuaj antihypertensive. Lorista yog ib qho tshuaj zoo. Kuv tsis muaj kev phiv tshuaj vim nws. Nws tsis muaj lub zog ua tau zoo thiab txo qis maj mam nce, uas kuv nyiam. Txoj kev cia li dhia ceev ceev hauv ntshav siab yog qhov txaus ntshai, thiab nrog kev poob qis sai sai, Kuv hnov ​​tus mob loj dua. Yog li no, rau cov uas tsuas yog tsim kev kub siab, cov tshuaj no yuav pab tau zoo. Tab sis nrog cov teeb meem kub siab, nws yuav tsis pab - cov tshuaj muaj zog ntau nrog kev ua nrawm yog xav tau ntawm no.

Ekaterina, 46 xyoo

Kuv tsis muaj qhov kev xav zoo tshaj plaws txog cov tshuaj no. Kuv siv lwm yam twj txhua lub sijhawm, thiab nws tau pab kuv. Tab sis kuv tsis nco qab yuav tshuaj, thiab kuv yuav tsum tau siv kuv tus poj niam lub tshuaj. Cov tshuaj no tau dhau los ua Lorista. Nws siv sij hawm ntau hnub, thiab txhua yam zoo, thiab tom qab ntawd lub siab pib nce. Kuv xav tias kuv tsis nco qab noj tshuaj thiab haus lwm ntsiav tshuaj. Nws tsuas muaj zuj zus. Lub siab poob qis me ntsis, tab sis kuv lub taub hau pib mob, thiab xeev siab thiab kiv taub hau. Txhua yam nws tau mus ntsib kws kho mob. Thiab nws kuj tseem cem kuv, hais tias cov tshuaj no tsis haum rau kuv. Tej zaum nws hais yog lawm.

Victor, 49 xyoo

Cov neeg mob lub tswv yim hais txog txoj kev kho mob feem ntau yog qhov zoo. Cov kev xav tsis zoo feem ntau yog los ntawm cov neeg uas tau ua cov kev coj tus kheej.

Hauv cov kab mob ntawm cov kab mob ntawm lub tso zis, cov tshuaj tiv thaiv kev tiv thaiv kab mob qee zaum siv, uas suav nrog Lorista. Cov tshuaj no tshem tawm cov dej noo ntau dhau ntawm lub cev, yog li lawv ua haujlwm zoo rau kev o tshwm sim los ntawm lub raum tsis ua haujlwm.

Tab sis qee qhov kev tiv thaiv kab mob ntawm cov kab mob tso zis yog qhov tsis zoo rau lawv siv. Nws yog ib qho tsim nyog yuav tsum ua tib zoo kawm cov lus qhia thiab ua raws nws.