Diabeton: cov lus qhia rau kev siv, cim ntsuas, tshuaj xyuas thiab analogues

Diabeton yog cov tshuaj hypoglycemic los ntawm cov pab pawg ntawm sulfonylurea derivatives ntawm 2nd tiam, uas ua rau hauv cov qauv ntawm cov ntsiav tshuaj rau kev tswj hwm qhov ncauj. Lub ntsiab sib txawv los ntawm cov tshuaj zoo sib xws yog qhov muaj cov nplhaib N-muaj heterocyclic nrog kev ua kom cov kabmob endocyclic.

Diabeton MV yog daim ntawv ntev, nws yuav tsum tau noj tsawg dua thiab tuaj yeem hloov ob peb koob tshuaj ntawm daim ntawv tso tawm qauv.

Hauv hom 2 mob ntshav qab zib mellitus, Diabeton pib kev tsim tawm thaum ntxov ntawm insulin los ntawm tus txiav ua teb rau kev nce ntxiv hauv cov ntshav qab zib, thiab ntxiv rau qhov ib txwm ua theem thib ob ntawm insulin secretion. Ib qho kev nce ntxiv hauv insulin ntau dua tshwm sim nyob rau hauv teb rau cov khoom noj thiab qabzib nkag mus rau cov hlab ntshav.

Cov tshuaj ua haujlwm nquag - Gliclazide - muaj kev ua haujlwm kho ob yam, ua pov thawj cov khoom noj metabolism, hemovascular thiab antioxidant zog. Cov tshuaj nquag Diabeton ua tau zoo nce cov rhiab heev ntawm cov ntaub so ntswg mus rau insulin.

Diabeton MV 60 mg, duab ntawm cov tshuaj

Tom qab siv cov tshuaj, qhov mob rhiab ntawm peripheral cov ntaub so ntswg rau insulin yog nce los ntawm 32%, qhov nqus ntawm cov piam thaj hauv cov leeg nqaij txhim kho - qhov no zoo heev rau kev muaj peev xwm tswj ntshav qab zib thiab ntshav qab zib mellitus. Cov nyhuv ntawm gliclazide tau piav qhia los ntawm qhov tseeb tias nws pab insulin ua rau cov leeg glycogen synthetase thiab ua rau cov kev hloov kho tom qab hloov hauv GLUT4 ntsig txog cov piam thaj.

Mob ntshav qab zib 60 mg zoo txo cov ntshav qab zib vim kev ua kom muaj zog ntawm insulin secretion los ntawm β-hlwb ntawm cov txiav. Hauv cov neeg mob uas muaj ntshav qab zib hom 2, cov tshuaj no ua kom zoo thaum ntxov ntawm insulin secretion thiab txhim kho qib 2 ntawm insulin ntau lawm, uas yog txhaws hauv cov ntshav qab zib.

Tom qab noj cov tshuaj, cov tshuaj nquag ua rau lub cev ua haujlwm ntawm cov islets ntawm Langerhans, uas zoo sib xws ntawm cov txiav. Ib qho ntxiv, 60 mg Diabeton ntsiav tshuaj tiv thaiv cov ntshav txhaws hauv cov hlab ntshav ntu, qhov ntshav ntws qeeb.

Diabeton tseem tsis tau muaj pov thawj ua rau kev rog vim tias cov tshuaj cuam tshuam rau thaum ntxov ntawm insulin ntau lawm thiab tsis ua rau hyperinsulinemia. Ntawm qhov tod tes, tshuaj pab txo cov rog hauv cov neeg mob rog, ntawm chav kawm, nrog kev noj zaub mov kom haum.

Feem ntau, kev noj tshuaj ib zaug txhua hnub ntawm Diabeton MB muab txoj kev kho zoo ntawm cov tshuaj nquag hauv cov ntshav rau 24 teev, thiab tuaj yeem hloov 2 koob tshuaj ntawm cov qauv tshuaj.

Kev ntsuas rau siv

Cov cim tseem ceeb rau kev noj cov ntshav qab zib yog hom 2 mob ntshav qab zib mellitus (DM) thiab kev tiv thaiv ntawm nws cov teeb meem.

Ntshav Qab Zib Hom 2 uas tsis muaj txiaj ntsig zoo rau cov piam thaj hauv qab los ntawm kev noj zaub mov, kev tawm dag zog thiab poob phaus,
kev tiv thaiv ntawm kev cuam tshuam ntawm cov ntshav qab zib hom 2 cuam tshuam nrog cov ntshav siab hauv qab.

Cov lus qhia rau kev siv tshuaj ntshav qab zib 60 mg, noj ntau npaum

Cov tshuaj yog npaj rau cov laus xwb.

Kev xaiv koob tshuaj Diabeton yuav tsum tau ua raws li qhov kev nyeem ntawv txog qib ntawm cov piam thaj hauv cov ntshav thaum lub sijhawm pib siv tshuaj. Kev maj mam nce ntxiv hauv cov tshuaj tuaj yeem nqa tawm tsawg kawg tom qab 14 hnub tom qab noj tshuaj.

Tus txheej txheem thawj zaug tshuaj yog 30 mg rau ib hnub (1/2 ntsiav tshuaj Ntshav Qab Zib 60 mg.).

Cov koob tshuaj tsim nyog yog xaiv tau ncaj qha, raws li cov ntsuas ntawm cov piam thaj hauv cov ntshav thiab glycated hemoglobin HbA1C. Yog tias qhov tshuaj thawj zaug tsis txaus, lawv hloov mus rau Diabeton 60 mg (tag nrho cov ntsiav tshuaj) thiab lwm yam. Lub sijhawm nruab nrab ntawm nce ntxiv cov koob tshuaj yuav tsum yog tsawg kawg 2 lub lis piam, nrog saib xyuas zoo ntawm cov piam thaj ntau ntau.

Qhov tshuaj ntau ntau yog 120 mg ib hnub twg.

Ntshav qab zib yog sib xws nrog lwm cov tshuaj mob ntshav qab zib. Ib lub tshuaj ntawm Diabeton 60 mg tuaj yeem hloov pauv los ntawm 1/2 ntsiav tshuaj ntawm Diabeton MB 60 mg. Thaum hloov mus rau tus neeg mob los ntawm cov tshuaj Diabeton 60 mg rau Diabeton MB, nws yog ib qho tseem ceeb uas tswj cov qib qabzib ntawm lub ntsuas ob peb zaug hauv ib hnub.

Yog tias koj plam ib lossis ntau dua ntawm cov tshuaj, koj tsis tuaj yeem siv ntau dua koob tshuaj ntxiv, koob tshuaj ploj yuav tsum noj nyob rau hnub tom ntej. Hauv cov lus yooj yooj yim - tsis txhob yuam kev ntawm lub sijhawm tau txais mus kawm, yog tias koj plam - tsuas yog noj cov tshuaj ntxiv tom ntej raws li lub sijhawm. Tsis pub txhaj ob npaug lossis ntau zaus rau prema!

Rau cov neeg laus (tshaj 65 xyoo), yuav tsum tau kho ntawm kev tswj hwm lossis noj ntxiv.

Hauv cov neeg mob uas mob raum tsis tshua mob pes tsawg lossis qis qis, cov tshuaj kho tau muab rau hauv tib lub sijhawm ib yam li cov neeg mob uas lub raum tsis ua haujlwm. Cov koob tshuaj zoo li no tau pom tseeb los ntawm kev kuaj mob hauv tsev kho mob.

Cov kev thaiv tsis zoo thiab cov tshwm sim

Lub ntsiab contraindications ntawm cov tshuaj:

Cov tib neeg lub cev tsis haum rau cov tshuaj muaj yees (gliclazide lossis rau ib qho twg ntawm cov tshuaj,
Ntshav qab zib mellitus (hom 1), tshwj xeeb yog cov hluas, keto-acidosis, ntshav qab zib muaj koob muaj npe,
Mob rau hepatic lossis lub raum tsis ua haujlwm,
Miconazole txoj kev kho,

Diabeton yog contraindicated rau kev siv thaum cev xeeb tub thiab thaum pub niam mis.

Cov tshuaj muaj pes tsawg leeg suav nrog lactose, yog li Diabeton tsis pom zoo rau cov neeg mob ua tsis taus dab tsi, galactosemia, glucose-galactose malabsorption.

Nws tsis pom zoo kom siv cov tshuaj no ua ke nrog phenylbutazone lossis danazole.

Noj ntau dhau

Cov tsos mob tseem ceeb ntawm kev siv ntau tshaj ntawm ntshav qab zib yog ntshav qog ntshav qab zib.

Hauv cov teeb meem loj (nrog lub cev tsis nco qab "tsis nco qab lawm"), kev tso dej ceev ceev ntawm hypertonic dextrose (qabzib) daws ntawm 40% yog tsim nyog.

Sab sij huam

Cov lus qhia rau kev siv Diabeton qhia txog cov kev mob tshwm sim hauv qab no:

Ntau yam mob plab zom mov: ntuav, zawv plab, xeev siab, mob plab, cem quav, qee zaum, cholestatic jaundice,
Kev tsis txaus siab ntawm cov hlab plawv: thrombocytopenia, ntshav liab, agranulocytosis lossis mob leukopenia,
Reversible nce siab ntawm daim siab enzymes (ALT, AST, alkaline phosphatase), kab mob siab (tsis tshua muaj), hyponatremia
Ntau yam kev txhaum fab hnyav (raws li kev ntsuam xyuas ntawm tus kab mob ntshav qab zib - tsis tshua muaj txaus),
Cov neeg pom kev ua kom tsis pom kev zoo, feem ntau thaum pib tshuaj,
Kev ntshav siab.

Nws ua tau kom txo cov ntshav qog ntshav qab zib los ntawm Diabeton los ntawm barbiturates, ntau yam diuretics (thiazide, ethacrylic acid, furosemide), progestogens, diphenin, estrogen, rifampicin, glucocorticosteroids.

Cov tshuaj tiv thaiv ntshav qab zib, cov npe tshuaj

Tus mob ntshav qab zib tuaj yeem hloov nrog cov tshuaj yeeb tshuaj hauv qab no, cov npe tshuaj:

Vero-Glyclazide,
Glidiab MV,
Glisid
Glyclazide
Lub Neej
Glucostabil,
Diab phem
Diabefarm
Diabinax
Diabresid
Medoclacid
Predian
Khaws.

Nws yog ib qho tseem ceeb kom nkag siab tias cov lus qhia rau kev siv Diabeton, tus nqi thiab tshuaj xyuas tsis siv rau cov tshuaj analogues thiab tsis tuaj yeem siv los ua cov lus qhia rau kev siv tshuaj ntawm cov sib thooj lossis cov nyhuv. Txhua txhua teem sijhawm kho yuav tsum ua los ntawm kws kho mob. Thaum hloov ntshav qab zib cov ntshav nrog tshuaj analogue, nws yog ib qho tseem ceeb kom sab laj nrog kws tshaj lij, koj yuav tsum tau hloov kho txoj kev kho, kev noj tshuaj, thiab lwm yam.

Tsis txhob tus kheej noj tshuaj - nws yog lub neej hem!

Pharmacodynamics thiab pharmacokinetics

Lub ntsiab, tseem ua tshuaj yog gliclazideCov. Kev siv tshuaj tiv thaiv kabmob hypoglycemic los ntawm pawg thib ob sulfonylurea. Glyclazide yog sulfonylurea derivative. Nws muaj lub nplhaib azobicyclooctane, uas nws paub qhov txawv ntawm nws cov tshuab ntawm kev txiav txim los ntawm cov piam thaj txo qis ntawm qhov loj thiab sulfonamides.

Cov tshuaj kuj muaj hemovascular, metabolic thiab antioxidant ntawv. Raws li cov ntshav qab zib ntshav qab zib, cov ntsiab lus ntawm cov piam thaj hauv cov ntshav yuav txo qis (vim tias kev txhim kho ntawm insulin los ntawm tshwj xeeb pancreatic beta hlwb).

Hauv cov neeg mob nrog mob ntshav qab zib yam thib ob ntawm cov tshuaj xa rov qab thaum ntxov siab hauv kev tsim khoomtshuaj insulin, thiab nce qib ntxiv ntawm cov insulin secretion. Kev nce ntawm cov tshuaj insulin tshwm sim ua ntej noj mov lossis piam thaj hauv lub cev.

Antioxidant thiab hemovascular cuam tshuam ntawm cov tshuaj txo cov kev pheej hmoo ntawm cov teeb meem ntshav qab zib. Mob ntshav qab zib tiv thaiv microthrombosis vim muaj ib nrab ntawm kev tsis sib xyaw ua ke, platelet adhesion, txo qis ntawm cov platelet ua cim.

Cov tshuaj tsub kom qhov kev ua ntau ntawm tPa, cuam tshuam rau cov kev ua haujlwm fibrinolytic ntawm phab ntsa endothelial ntawm lub nkoj.

Cov hauj lwm antioxidant ntawm glycazide ua tiav los ntawm kev txo qis peroxide lipids hauv cov ntshav ntshav, nce kev ua haujlwm ntawm erythrocyte dismutase, ntshav thiols, muaj peev xwm ua tau tag nrho antioxidant.

Gliclazide yog metabolized hauv lub siab.

Cov Yuav Tsum Muaj

Ntshav qab zib ketoacidosisyam 1 mob ntshav qab zib mellitus, mob hnyav mob lub raum thiab kab mob siab, ntshav qab zib ua ntej, comacev xeeb tub.

Nrog kev ceev faj, Diabeton yog tseg rau tus neeg laus, tom qab kev kub hnyiab ntev. Siv tsis tau rau hauv kho mob me nyuam yaus.

Sab sij huam

Nrog rau cov zaub mov tsis txaus, qhov ua txhaum ntawm kev tsuas tshuaj yog muab sau tseg ntshav qogkev tshaib kev nqhis, nkees, mob taub hau, tawm hws sai sai lub plawv dhiainsomnia ntxhov siabtsim txom hnyav, tsis saib xyuas, pom qhov tsis zoo,paresis, tshee hnyokev nyuaj siab, tsis saib xyuas, aphasia, qhov txawv txav tsis sib xws, delirium, hypersomnia, cramps.

Kev kho mob txoj hnyuv: mob dyspeptic, cholestatic jaundice, qab los noj mov, muaj ntau cov nplooj siab enzymes.

Hematopoietic plab hnyuv siab raum: inhibition ntawm cov pob txha hlwb hematopoiesis.

Noj ntau dhau

Hnov nco qab, hypoglycemia, coma.

Nws yog ib qho tsim nyog yuav tau qhia 40% hypertonic dextrose kev daws, noj qab zib sab hauv, 2 mg glucagon.

Saib xyuas ntshav qab zib txhua 15 feeb. Noj zaub mov ntau hauv carbohydrates (yooj yim zom tau).

Kev sib txuam

H2-histamine receptor blockers, ACE inhibitors, NSAIDs, fibrates, antifungal tshuaj, coumarin anticoagulants, MAO inhibitors, anabolic steroids, sulfonamides, biguanides, cyclophosphamides, pentoxifyllinetheophylline tetracycline, reserpine, disopyramide, insulin,ethanol, allopurinol txhim kho cov nyhuv ntawm Diabeton.

GKS, barbiturates, antiepileptic, adrenostimulants, BMKK, thiazide diuretics, triamteren, furosemide, baclofendiazoxide, asparaginase, triamteren, morphine, isoniazidterbutaline, ritodrin, glucagon, salbutamol, rifampicin, estrogenschlorpromazine nicotinic acid ua kom tsis muaj zog ntawm cov tshuaj.

Cov lus qhia tshwj xeeb

Nrog rau cov ntshav qab zib decompensation, kev phais mob, kev siv tshuaj insulin yuav tsum tau txiav txim siab. Thaum siv cov tshuaj cawv, qhov kev pheej hmoo ntawm kev muaj ntshav qab zib ntau zuj zus.

Nrog rau kev xav, lub cev nqaij ntawm lub cev, nws yog qhov tsim nyog los kho lub koob tshuaj ntawm cov tshuaj ntshav qab zib.

Cov neeg laus, cov neeg mob pituitary-adrenal tsis txaus ntseeg tshwj xeeb tshaj yog rau cov tshuaj hypoglycemic.

Ua rau kom qeeb ntawm lub nrawm ntawm lub cev psychomotor.

Diabeton analogues

Cov tshuaj ntawm cov tshuaj tuaj yeem raug hu ua cov nyiaj: Glidia, Glykinorm, Gliklada, Gliclazide, Lub Neej, Kev kuaj mob, Diazide, Panmicron, Khaws.

Kev Ntshav Qab Zib

Cov tshuaj yog yam ntxwv ua haujlwm zoo rau kev txo qis ntshav qab zib, nws yog qhov yooj yim los siv piv nrog kev txhaj tshuaj insulin. Cov kev mob tshwm sim yuav luag tsis pom, tej zaum yuav tsis haum rau txhua tus neeg mob.

Kev tshuaj xyuas txog tus neeg mob ntshav qab zib hauv kev tawm dag zog hauv lub cev ua rau muaj qhov sib txawv ntawm cov tshuaj uas yog txhais tau tias kom hnyav. Txawm li cas los xij, cov kws kho mob tsis pom zoo kom siv cov tshuaj thiab, tshwj xeeb, Diabeton tsis yog rau lawv lub hom phiaj uas tau npaj tseg. Qhov no tuaj yeem ua kom muaj kev phom sij rau kev noj qab haus huv. Kev siv tshuaj noj tuaj yeem ua rau ntshav qab zib hauv lub cev.

Kev siv cov sulfonylureas hauv kev kho mob

Cov tshuaj pab pawg yog suav hais tias yog ib qho txiaj ntsig zoo tshaj plaws los tswj cov ntshav qab zib.

Cov lus qhia tseem ceeb ntawm txoj kev kho yuav tsum ua tiav cov hom phiaj hauv qab no:

kev tsim tawm ntawm insulin hormone secretionꓼ
txo qis cov roj ntsha insensitivity ntawm cov hlwb клеток
ncua kev kawm ntawm cov kua nplaum ua ke thiab ua kom qeeb kom nws nqus tau rau hauv cov ntshav los ntawm cov hnyuv ꓼ
kev txhim kho ntawm kev tshwm sim ua txhaum ntawm qhov feem ntawm lipid feem hauv cov ntshav.

Ua raws li kev kawm ntawv thiab qhov xwm txheej ntawm kev txhim kho cov txheej txheem pathological, cov kws kho mob tau tshaj tawm txog kev siv cov tshuaj tsim nyog los ntawm ib los yog ob peb pawg ib zaug. Derivatives ntawm sulfonylureas tuaj yeem dhau los ua ib qho ntawm cov tshuaj no.

Sulfonylurea yog ib yam tshuaj hypoglycemic uas yog tsim los ntawm sulfamide thiab siv rau hauv kev kho mob ntshav qab zib. Lub tswv yim tseem ceeb ntawm kev nqis tes ntawm cov tshuaj no yog tswj lub qhov ua kom lub cev tuag ntawm pancreatic beta hlwb los ua cov tshuaj insulin xav tau. Vim cov nyhuv no, tsis tsuas yog ntxiv cov khoom tsim tawm hauv lub cev lawm, tab sis kuj tseem rhiab ntawm lub cev nqaij rau nws nce ntau.

Tsis tas li ntawd, qhov zoo tshwm sim ntawm sulfonylurea tshuaj yog:

Nce cov kev cuam tshuam ntawm insulin, uas ua rau kev txo qis hauv cov piam thaj ntau dua.
Lawv nruab nrab ua haujlwm ntawm cov enzymes uas zom cov insulin uas twb muaj lawm.
Ua kom ntau ntawm cov insulin receptors rau ntawm cov cell.
Kev lom zem rau kev cuam tshuam cov txheej txheem ntawm kev siv ntshav qabzib los ntawm lub siab ua haujlwm.
Lawv nce ntxiv kev nqus thiab oxidation ntawm cov piam thaj.

Cov tshuaj zoo li no feem ntau yog kho rau cov neeg uas lub cev hnyav, tsis raug kev txom nyem los ntawm kev rog.

Txhua qhov sulfonyl derivatives raug nthuav tawm hauv cov qauv tshuaj uas muaj peb tiam neeg.

Thawj cov tshuaj uas tsis siv rau hauv kev kho mob niaj hnub, vim tias lawv muaj cov tshuaj lom rau tib neeg lub cev

Kev tsim tshuaj thib ob, uas muaj kev nyab xeeb dua, thiab yog li ntawd tau siv ncaj qha rau kev kho mob. Lawv sawv cev los ntawm ib yam muaj sia xws li gliclazide, uas yog ib feem ntawm Diabeton ntsiav tshuaj.

Cov tshuaj thib peb, uas muaj qhov ua kom ntev thiab cia koj noj tshuaj txo suab thaj hauv cov koob tshuaj qis kom ua tiav cov txiaj ntsig xav tau.

Lawv lub ntsiab tseem ceeb ua yog glimepiride.

Cov tshuaj muaj suab thaj txo qis yog dab tsi?

Cov tshuaj Diabeton yog ib qho tshuaj hypoglycemic, uas tau suav nrog pawg pab pawg ntawm sulfonide derivatives ntawm lub cim thib ob.

Lub hauv paus ntawm nws cov muaj pes tsawg leeg yog cov tshuaj nquag muaj gliclazide, vim tias cov nyhuv tsim nyog ntawm kev noj cov tshuaj yog nqa tawm.

Tsis zoo li lwm yam tshuaj sulfonylurea (piv txwv li, Glibenclamide), Diabeton muaj cov ntshav tsawg dua qub, uas cuam tshuam rau microcirculation, hemostasis, cov ntaub ntawv hematological thiab rheological ntawm cov ntshav. Nws yog cov khoom no uas yog qhov tseem ceeb tshaj plaws rau cov neeg mob uas kuaj pom tus mob ntshav qab zib hom 2.

Cov tshuaj Diabeton kho lub zog thaum ntxov ntawm insulin secretion, uas tau cuam tshuam los ntawm kev txhim kho ntawm cov txheej txheem pathological. Tsis tas li ntawd, ntawm lub zog pharmacological ntawm cov tshuaj suav nrog:

txo hauv platelet aggregationꓼ
nce kev ua si ntawm cov nqaij mos activator ntawm plasminogen thiab prekallikreinꓼ
neutralization ntawm kev pheej hmoo ntawm cov ntshav txhaws ꓼ
txo qis ntawm oxidative kev nyuaj siab thiab kev lag luam ntawm kev nplaum nplaum moleculesꓼ
ib qho kev txo qis ntawm cov pro-atherogenic alpha hlav necrosis yam, vim tias ib qho kev tiv thaiv kev ua haujlwm raug pom hais txog kev txhim kho cov kab mob plawv thiab teeb meem nrog cov ntshav tsis txaus nyob rau hauv cov ntshav qab zib ꓼ
kev ua kom zoo ntawm cov txheej txheem fibrinolysis.

Tsis tas li ntawd, rau Diabeton, cov lus qhia rau kev siv qhia tau tias cov tshuaj muaj tsis tsuas hypoglycemic cov khoom ntiag tug, tab sis kuj muaj hemovascular, metabolic thiab antioxidant cov yam ntxwv. Xws li cov qauv tshuaj pharmacological tuaj yeem ua rau muaj kev pheej hmoo ntawm ntau yam mob uas tshwm sim los ntawm cov ntshav qab zib.

Qhov ntsuas dab tsi rau nws siv nyob ua ib ke?

Cov tshuaj Diabeton tau raug faib nyob hauv cov tsev muag tshuaj hauv nroog yog tias muaj tshuaj kho mob uas kws kho mob tau txib tuaj.

Ib tus kws tshaj lij ntawm kab mob kev nkeeg txiav txim siab qhov xav tau chav kawm kho mob siv tshuaj kho mob.

Tsis zoo li cov tshuaj los ntawm cov pab pawg biguanide (xws li Metformin), Diabeton rau qhov poob phaus tsis siv. Ntxiv mus, qee cov neeg mob noj cov tshuaj no tau sau tseg nce hauv lawv qhov hnyav thaum kho.

Raws li cov lus piav qhia rau cov tshuaj, cov cim tseem ceeb rau kev siv cov tshuaj no yog:

Kev txhim kho mob ntshav qab zib mellitus ntawm daim ntawv insulin-ywj siab raws li kev kho mob lossis kho txoj hauv kev. Feem ntau xws li npaj ntawm sulfonyl derivatives pib siv tom qab kev siv tshuaj tsis siv tshuaj (ua raws li cov zaub mov tsim nyog thiab ua haujlwm ntawm lub cev) tsis tsim cov txiaj ntsig xav tau
Yuav kom ua kom nruab nrab txoj kev pheej hmoo thiab tiv thaiv lub hom phiaj, los tiv thaiv qhov pom ntawm ntau cov kev tsis zoo uas kawm txog tus mob ntshav qab zib nqa.

Ua ntej tshaj plaws, kev siv cov tshuaj yuav tiv thaiv cov kev tshwm sim ntawm cov teeb meem micro-vascular pathologies, xws li retinopathy thiab nephropathy, thiab lwm yam kab mob ntawm cov hlab plawv - mob plawv lossis mob hlab ntsha tawg.

Cov lus qhia rau kev siv tshuaj

Cov tshuaj Diabeton muaj nyob hauv daim foos.

Nyob rau tib lub sijhawm, cov tshuaj muaj pes tsawg leeg suav nrog yim yim milligrams ntawm cov kev ua haujlwm nquag.

Ntshav qab zib cov ntsiav tshuaj yog noj raws li cov lus qhia nruj ntawm tus kws kho mob.

Raws li txoj cai, txoj kev kho mob ntawm kev noj tshuaj yog siv raws cov qauv hauv qab no:

siv cov tshuaj ib hnub ib zaug tsis hais txog kev noj zaub mov zoo li cas (nyiam kom muab rau thaum sawv ntxov) ꓼ
Diabeton tsiav tshuaj yuav qaug cawv qhov ncauj nrog cov dej ntxhia ntau ntau yam tsis muaj roj
kev noj tshuaj txhua hnub tau teev nyob rau hauv thaj tsam ntawm yim caum milligrams ntawm cov tshuaj nquag nquag nrog kev muaj peev xwm nce ntxiv yog tias tsim nyog, thaum ib txwm pib qhov kev kho mob tshwm sim tshwj xeeb nrog kev siv cov koob tshuaj tsawg kawg nkaus, uas tau muab cia hauv ib ntsiav tshuaj ntawm cov tshuaj,
cov koob tshuaj tsim nyog raug tshuaj yog tshuaj los ntawm tus kws kho mob mus kawm ib tus zuj zus rau txhua tus neeg mob, coj mus rau hauv tus account yam ntxwv ntawm tus yam ntxwv ntawm tus mob, lub hnub nyoog ntawm tus neeg mob thiab theem ntawm hypoglycemiaꓼ
txhawm rau tshem tawm qhov tshwm sim ntawm kev phiv, thaum hla cov tshuaj tom ntej, koj yuav tsum tsis txhob nce cov tshuaj nquag ntxiv lwm zaus koj siv ꓼ
qhov ntau tshaj plaws ntawm kev noj tshuaj txo cov piam thaj thaum nruab hnub yuav tsum tsis pub ntau dua 320 mg, uas yog, plaub ntsiav tshuaj, thaum lub sijhawm yuav tsum tau noj ntau dua ntawm cov tshuaj yuav tsum tau nrog los ntawm kev nce ntxiv ntawm cov koob tshuaj thaum nruab hnub (cov tshuaj yog qaug cawv ob mus rau peb zaug ib hnub, nyob ntawm seb cov lus pom zoo kws kho mob).

Qee qhov, muaj kev kho ua ke, uas suav nrog kev noj tshuaj los ntawm ntau cov chav kawm.

Yog li, cov nyhuv ntawm txhua cov tshuaj rau tus neeg mob lub cev tau kho kom zoo.

Cov ntsiav tshuaj hypoglycemic tej zaum yuav raug siv los ua ke nrog tshuaj los ntawm cov pab pawg biguanide, alpha glucosidase inhibitors, lossis kev kho tshuaj insulin. Txoj kev kho kom zoo yuav tuaj yeem txo cov kev pheej hmoo ntawm ntau yam mob, nrog rau kev ua kom ib ce nrawm dhau mus hauv cov ntshav qabzib.

Nws yuav tsum tau yug los hauv lub siab hais tias cov tshuaj noj ib zaug dhau ntawm cov tshuaj uas tau pom zoo tuaj yeem ua rau kev txhim kho ntshav qab zib.

Yog li, thaum ua txoj kev kho kom zoo, tus neeg mob yuav tsum ntsuas ntsuas cov suab thaj hauv cov ntshav ntau ntau.

Dab tsi yog cov kev pheej hmoo ntawm kev siv tshuaj?

Zoo li feem ntau cov tshuaj, Diabeton muaj kev phiv thiab contraindications.

Yog tias tsis pom zoo rau kev kho mob thiab kev siv tshuaj ntau ntxiv, kev saib xyuas ntshav qab zib ntau tshaj plaws yuav tsum pom.

Qhov tshwm sim no ua rau lub xeev ntawm cov ntshav qab zib tsis xeev ua tsis taus pa, tsis nco qab zoo thiab muaj ntshav qab zib tsawg. Txhawm rau tshem tawm cov tsos mob ntawm kev noj ntau dhau, nws yog qhov yuav tsum tau qhia tus neeg mob txoj kev daws teeb meem hypertonic dextrose (ntawm kev sib tov ntawm plaub caug feem pua) thiab ib qho kev daws teeb meem glucagon, thiab tseem muab qab zib me ntsis.

Nws raug nquahu ntxiv tias cov ntshav qabzib hauv cov ntshav yuav tau saib xyuas txhua kaum tsib feeb. Lwm qhov tsis zoo ntawm kev overdose yog qhov ua tau ntawm cerebral puffiness. Hauv qhov xwm txheej no, cov kws kho mob tau sau ntawv rau Dexamethasone thiab Mannitol ua kev kho mob.

Nws yuav tsum raug sau tseg tias kev noj tshuaj yog txwv tsis pub siv rau hauv kev ua kom pom ntawm qee yam xwm txheej thiab cuam tshuam.

Tus mob ntshav qab zib contraindications muaj cov hauv qab no:

Txoj kev ua kom paub ketoacidosis ntawm hom ntshav qab zib.
Daim foos-insulin-daim ntawv foos ntawm kev txhim kho ntawm tus txheej txheem pathological.
Cov kab mob hnyav ntawm cov nruab nrog sab hauv xws li ob lub raum thiab mob siab.
Lub xub ntiag ntawm glycemic coma thiab kab mob koob meej.
Thaum cev xeeb tub thiab pub niam mis.
Yog tias tus neeg mob tau mob kub hnyav lossis mob hnyav.
Hauv cov menyuam yaus thiab cov neeg laus laus.
Nyob rau hauv muaj ib tug neeg intolerance mus rau ib los yog ntau Cheebtsam ntawm cov tshuaj.

Tsis tas li ntawd, thaum pib ntawm lub hom phiaj ntawm kev kho mob, nws yog ib qho tsim nyog los saib xyuas cov kev noj qab haus huv thiab lub xeev kev noj qab haus huv, vim tias muaj ntau yam tsis zoo los ntawm sab hauv cov nruab nrog sab hauv thiab cov kab ke tuaj yeem tsim kho. Ua ntej tshaj, koj yuav tsum tau them sai sai rau qhov muaj kev tsis haum tshuaj, thiab yog tias muaj qhov tshwm sim, tsum tsis txhob noj cov tshuaj.

Tsis tas li, cov kev mob tseem ceeb los ntawm kev noj tshuaj muaj xws li:

txo cov ntshav qab zib hauv qab cov theem uas tsim nyog tau txais
nce los yog tsis qab los noj mov, yuag rog ntxiv
lub cev kev nkees heev thiab poob lub zog loss
tawm hws ntau dhau ꓼ
tachycardiaꓼ
pom kev pom ꓼ
teeb meem pw tsaug zog thiab insomniaꓼ
tsis paub cai ntawm kev ntxhov siab, kev txob txob lossis txob taus ꓼ
qhov zoo li cramps hauv plab plab hlaub nqaij ꓼ
tso pa nrov plhu
nce ci enzymesꓼ
hypersomnia.

Yog tias muaj qhov tshwm sim tsis zoo, nws yog qhov yuav tsum tau qhia rau tus kws kho mob uas tau koom nrog qhov no txhawm rau kom ntsuas qhov tsim nyog lossis hloov cov tshuaj.

Kuv yuav siv tau cov tshuaj twg los hloov?

Cov tshuaj kho mob niaj hnub no muab ntau lub tswv yim uas qhia tau tias kev siv tshuaj ib txwm muaj nyob rau lub sij hawm ntev ua rau muaj kev puas tsuaj me ntsis ntawm pancreatic beta hlwb thiab tuaj yeem pab txhawb kev tsim kab mob ntshav qab zib insulin-mellitus.

Hauv qhov xwm txheej no, txawm tias muaj lus sib liam li no los, cov kws kho mob tseem siv cov tshuaj los kho cov pathology.

Txog Tus Mob Ntshav Qab Zib, cov neeg kuaj xyuas cov mob muaj ntau yam. Qee tus neeg hais tias cov tshuaj muaj txiaj ntsig zoo thiab yooj yim zam, thaum lwm tus neeg npau taws thaum tsis muaj txiaj ntsig thiab muaj qhov hnyav nce ntxiv tom qab kev kho.

Koj yuav tsum tsis txhob ua txhua qhov kev tshuaj xyuas txog tus mob ntshav qab zib ib yam nkaus, vim tias txhua yam kab mob ib leeg ib leeg, thiab qhov uas tsis haum rau ib tus neeg yuav tsim nyog rau lwm tus.

Tus nqi ntawm ib cov tshuaj nyob rau hauv kev ua lag luam yog kwv yees li peb puas rubles. Yog tias tsim nyog, tus kws kho mob tuaj koom tuaj yeem hloov cov tshuaj nrog nws cov txheej txheem analogue.

Tsim cov ntsiav tshuaj siv tshuaj xws li:

Tag nrho cov tshuaj analogue saum toj no tau koom rau cov pab pawg ntawm sulfonyl derivatives ntawm tiam thib ob. Lawv qhov sib txawv nyob hauv cov tuam txhab tsim khoom lag luam (qee leej yog cov sawv cev ntawm cov tuam txhab txawv teb chaws chaw muag tshuaj, qee qhov yog tsim hauv Lavxias Lavxias), tus nqi thiab tus lej ntawm cov kev mob tshwm sim, contraindications.

Cov lus qhia txog Tus Mob Ntshav Qab Zib muaj nyob hauv cov yeeb yaj kiab hauv tsab xov xwm no.