Torvacard - cov lus qhia rau kev siv, tso tawm daim ntawv, cim, cov kev mob tshwm sim, analogues thiab tus nqi

Qhov cuab yeej zoo hauv kev tiv thaiv atherosclerosis yog Torvacard. Nws txo qis tag nrho cov roj (cholesterol) los ntawm 30–46%, cov lipoprotein tsawg-los ntawm 40-60%, thiab txo cov roj triglycerides. Nws feem ntau tau sau tseg txhawm rau txhawm rau tiv thaiv myocardial infarction nrog cov ntshav siab, mob hlab ntsha hauv plawv, mob plawv, thiab lwm yam kev mob plawv. Cov tshuaj yog tshwj xeeb tshaj yog rau cov ntshav qab zib.

Torvacard yog dab tsi

Lub chaw tsim khoom ntawm Torvacard yog lub tuam txhab Czech koom haum Zentiva. Qhov cuab yeej hais txog cov lipid-txo cov tshuaj, nws qhov kev ua raws li kev tiv thaiv kom tsis txhob muaj cov lipoproteins tsawg (LDL), uas nqa cov roj cholesterol thoob plaws lub cev. Txog rau qhov no, Torvacard txo qis tag nrho cov roj hauv lub cev (qhov kev cia siab poob qis hauv nws qhov "tsis zoo" yog 36-54%), thiab yog li ntawd cov tshuaj nyob rau hauv chav kawm ntawm statins.

Cov roj (cholesterol) nyob ua ke rau cov roj ntsha muaj cawv thiab noj ib feem hauv ntau cov txheej txheem hauv lub cev: nws koom nrog kev tsim cov vitamin D, kev tsim cov kua tsib kua qaub, cov tshuaj hormones steroid, nrog rau qhov chaw mos. Yim caum feem pua ntawm cov roj cholesterol yog tsim los ntawm lub cev, tus so los nrog zaub mov noj. Cov tshuaj tsis yaj ua rau dej, thiab yog li tsis tuaj yeem nkag mus rau hauv lub hlwb nrog cov ntshav ntws. Ua li no, nws ua ke nrog kev thauj cov protein, tsim cov lipoproteins ntawm qhov sib txawv.

Cov roj (cholesterol) nce mus txog cov hlwb zoo ua ib feem ntawm LDL, uas, txawm hais tias nws ua lub luag haujlwm tseem ceeb, hu ua "cov roj (cholesterol) phem" vim tias nws nyhav rau cov ntshav ntawm cov hlab ntsha. Cov lipoproteins uas ntau, HDL, uas paub tias cov roj (cholesterol) zoo, yog lub luag haujlwm rau tshem cov roj cholesterol hauv lub cev thiab ntxuav cov vascular phab ntsa. Cov theem siab ntawm HDL yog tus yam ntxwv ntawm lub cev muaj zog noj qab haus huv.

Yog tias qhov concentration ntawm LDL hauv cov ntshav siab dhau, "cov roj (cholesterol) zoo" yuav tsis tu lawv lub luag haujlwm. Raws li qhov tshwm sim, cov roj hauv plaques yog tso rau ntawm cov hlab ntshav vias, uas ua rau txhaws ntawm cov ntshav vim yog nqaim ntawm lub lumen ntawm cov hlab ntsha. Cov kev tso cai feem ntau ua rau phab ntsa ntawm cov leeg ntshav thiab cov hlab ntsha, uas ua rau lub ntsej muag ntawm cov ntshav txhaws, uas tsim thaum platelets thiab lwm lub hlwb pib kho cov qhov txhab.

Ua haujlwm dhau sijhawm, cov plahaum roj (plaques) ua kom tawv thiab hloov cov ntaub so ntswg zoo, uas yog vim li cas cov hlab ntsha, leeg ntshav, cov hlab ntuag poob lawv qhov elasticity. Nyob rau hauv quab yuam ntawm cov ntshav ntws, lawv feem ntau tawg, ua rau loj los me los ntshav. Yog tias hemorrhage tshwm sim hauv thaj av ntawm lub plawv lossis lub paj hlwb, lub plawv yuav tshwm sim. Txawm tias yuav tau txais kev pabcuam raws sijhawm, kev tuag yuav tshwm sim.

Txhawm rau txo cov roj synthesis, Torvacard inhibits cov kev ua ntawm enzyme HMG-CoA reductase, uas koom tes nrog cov roj ntsha ua kom muaj roj. Qhov no ua rau muaj kev txo qis hauv nws cov lus neeg sib tov, thiab nrog nws kom txo qis cov lipoproteins uas muaj tsawg. Ua ke nrog LDL, triglycerides kuj txo qis - ib hom rog uas muab lub cev nrog lub zog thiab koom nrog kev tsim cov lipoproteins. Qhov ntxiv yog tias qhov ntau ntawm cov "roj cholesterol" zoo hauv qab ntawm Torvacard nce.

Cov lus qhia siv Torvacard

Thaum siv tshuaj kho, tus neeg mob yuav tsum ua raws cov zaub mov noj kom txo qis lipid. Koj tuaj yeem siv cov tshuaj noj nrog ob qho khoom noj thiab ntawm lub plab khoob. Kev noj Torvacard thaum noj mov ua rau kom cov txheej txheem nqus qis, tab sis qhov ua tau zoo ntawm cov tshuaj rau qhov no tsis txo qis. Ua ntej kev kho mob, nws yog qhov yuav tsum tau ua kev soj ntsuam rau qib ntawm cov lipids hauv cov ntshav, hla lwm qhov kev kuaj mob tsim nyog.

Qhov siab tshaj plaws ntawm cov tshuaj hauv plasma yog pom ib teev lossis ob teev tom qab nws siv. 98% ntawm cov khoom nquag tom qab nqus mus rau hauv cov ntshav khi rau nws cov protein thiab tau nyiaj mus rau lub luag haujlwm. Feem ntau ntawm Torvacard tawm lub cev ua ib feem ntawm cov kua tsib tom qab ua los ntawm daim siab. Nrog zis, tsis pub ntau tshaj ob feem pua los tawm. Kev tshem tawm ib nrab-lub neej yog 14 teev.

Torvacard tuaj yeem txo qhov kev ua haujlwm ntawm cov enzyme HMG-CoA reductase vim nws atorvastatin. Cov tshuaj tau tso tawm hauv cov ntsiav tshuaj, hauv txhua - 10, 20 lossis 40 mg ntawm cov tshuaj nquag no. Ib pob muaj 30 lossis 90 ntsiav tshuaj. Ntxiv nrog rau cov tshuaj nquag, cov tshuaj muaj pes tsawg leeg suav nrog:

microcrystalline cellulose - normalizes lub plab zom mov, txo qis kev tsim cov roj thiab cov piam thaj, khi cov co toxins,
magnesium oxide - txo acidity, txhawb pob txha muaj zog, txhim kho txoj haujlwm ntawm lub siab, leeg, hlwb hlwb,
silicon dioxide - ib qho enterosorbent uas sib xyaw nrog cov co toxins, cov ua xua, cov kab mob thiab lwm cov khoom lag luam metabolic hnyav,
croscarmellose sodium - pab cov ntsiav tshuaj yaj sai tom qab noj,
magnesium stearate - txhawb kev tsim cov homogeneous loj hauv kev tsim cov ntsiav tshuaj,
hydroxypropyl cellulose - thickener,
lactose monohydrate yog ib qho muab tub lim.

Txhawb kev ntshav lipids (hyperlipidemia) yog qhov qhia txog kev teem caij Torvacard. Siv cov tshuaj thooj txhij ua ke nrog kev noj haus uas txo qis lipoproteins tsawg thiab triglycerides, ntau ntxiv "cov roj cholesterol zoo." Torvacard kuj tau hais tseg hauv cov xwm txheej hauv qab no:

siab concentration ntawm triglycerides hauv cov ntshav (hypertriglyceridemia),
dysbetalipoproteinemia,
ua ke hypertriglyceridemia thiab hypercholesterolemia (cov roj hauv siab),
heterozygous (thawj) thiab homozygous kab mob hypercholesterolemia, thaum khoom noj tsis zoo,
kab mob ntawm cov hlab plawv system nyob rau hauv qhov muaj dyslipidemia (ua txhaum ntawm qhov sib piv ntawm cov ntshav lipids) rau kev tiv thaiv mob stroke thiab myocardial infarction.

Nrog cov lus hais txog kev mob plawv, Torvacard cov ntsiav tshuaj tau sau tseg rau kev tiv thaiv mob stroke thiab lub plawv nres, pab txhawb cov txheej txheem vascular kev kho mob rov qab (rov qab kho dua tshiab), thiab txo cov kev pheej hmoo hauv tsev kho mob thaum muaj mob plawv. Kws tshuaj muab tshuaj rau thaum tsis muaj cov cim ntawm kev mob plawv (CHD), tab sis nws muaj qhov yuav tsum tau ua ntej rau nws qhov tshwm sim:

ntshav siab
haus luam yeeb
cov theem ntawm cov roj (cholesterol) zoo
hnub nyoog 55 xyoos
muaj keeb muaj mob muaj keeb.

Txhawm rau tiv thaiv kom txhob mob stroke, Torvacard yog tsim rau cov neeg mob ntshav qab zib hom 2 uas tsis muaj cov tsos mob ntawm kev mob plawv, tab sis muaj ntshav siab, retinopathy (puas tsuaj rau retina), cov protein nyob hauv cov zis (albuminuria), qhia tias muaj teeb meem lub raum. Qhia cov tshuaj yog cov ntshav qab zib haus luam yeeb. Nws yuav tsum raug sau tseg tias atorvastatin tuaj yeem ua rau cov ntshav qab zib hauv cov neeg uas nyob hauv tus kabmob no, thiab hauv cov ntshav qab zib nws nce cov piam thaj hauv qab. Vim li no, koj yuav tsum tau noj cov tshuaj Torvard, nruj saib xyuas cov lus pom zoo los ntawm tus kws kho mob.

Kev kho mob pib nrog ib koob tshuaj 10 mg ib hnub twg, uas maj mam nce mus txog 20 mg. Koj tsis tuaj yeem noj ntau dua 80 mg ntawm cov tshuaj ib hnub. Cov koob tshuaj yog xaiv los ntawm tus kws kho mob, coj mus rau hauv tus lej ntsuas, tus yam ntxwv ntawm tus neeg mob. Rau cov neeg mob homozygous hypercholesterolemia, qhov koob tshuaj yog raws nraim 80 mg. Lub sijhawm ntawm cov chav kawm ntawm kev kho yog txiav txim los ntawm tus kws kho mob. Qhov ua kom pom qhov tseeb tshwm sim tau pom ob lub lis piam tom qab thawj koob tshuaj thawj zaug. Ib hlis tom qab pib kev kho mob, yuav tsum kuaj ntshav lipids thiab kev kho mob yuav tsum tau kho.

Cov Yuav Tsum Tau Ua

Torvacard yog ua tiav rau hauv daim siab ua ntej tawm hauv lub cev, yog li ntawd cov tshuaj yog contraindicated nyob rau hauv yog tias muaj qhov mob loj ntawm cov kab mob no. Koj tsis tuaj yeem noj cov tshuaj nrog:

kom cov qib siab hloov pauv - enzymes lub luag hauj lwm rau cov metabolism hauv lub cev, cov concentration ntawm cov uas feem ntau nce nrog kab mob siab,
cov kab mob tsis haum rau lactose, qabzib, lactase deficiency,
hnub nyoog txog 18 xyoo
kev fab tshuaj rau cov tshuaj hauv cov tshuaj.

Tsis txhob hais kom sau Torvacard rau cov poj niam uas muaj hnub nyoog yug me nyuam uas tsis siv tshuaj tiv thaiv: statins tuaj yeem tsim kev puas tsuaj rau lub cev ntawm tus menyuam hauv plab. Thaum cev xeeb tub, cov concentration ntawm cov roj cholesterol thiab triglycerides ib txwm loj hlob, vim tias cov tshuaj no tsim nyog rau kev tsim cov me nyuam hauv plab tag nrho. Cov kev tshawb fawb txog cov nyhuv ntawm cov tshuaj rau ntawm cov menyuam mos tsis tau ua, tab sis nws paub tias statins muaj peev xwm nkag mus rau hauv niam mis thiab ua rau muaj kev phiv hauv menyuam thaum lub sijhawm lactation.

Torvacard tau ua tib zoo saib rau teeb meem nrog cov metabolism, dej-electrolyte tshuav, thiab ntshav siab. Kev quav dej cawv, kab mob siab, mob ntshav qab zib mellitus, mob qaug dab peg, kev raug mob tsis ntev los no, kev phais mob hnyav ntxiv yuav tsum muaj kev ceev faj thaum siv tshuaj, kev ua raws li cov tshuaj thiab kev kho mob.

Sab sij huam

Noj Torvacard tuaj yeem ua kev mob tshwm sim. Los ntawm lub paj hlwb tuaj yeem pom:

insomnia
mob taub hau
kev nyuaj siab
paresthesia - ib hom rhiab rhiab uas tshwm sim los ntawm kev kub nyhiab, tingling, goosebumps,
ataxia - kev ua txhaum ntawm kev sib koom tes ntawm kev txav ntawm cov nqaij sib txawv,
neuropathy yog qhov chaw mob sib txuas ntawm cov hlab ntsha uas tsis yog-khaus tawm.

Tej zaum yuav muaj teeb meem rau cov txheej txheem hauv plab: mob hauv lub plab, xeev siab, ntuav, raws plab los yog cem quav, hloov pauv ntawm lub siab, plab zom mov (ua haujlwm nyuaj thiab mob plab zom mov). Tus mob muaj kab mob siab, daj ntseg, mob daj ntseg. Lub cev cov leeg tuaj yeem teb rau Torvacard - mob plab, mob hauv cov leeg thiab pob qij txha, nraub qaum, mob myositis (mob rau cov leeg pob txha).

Ntawm cov kev mob tshwm sim ntawm cov tshuaj yog mob hauv siab, tinnitus, plaub hau poob, qaug zog, rog rog. Qee zaum cov raum tsis ua haujlwm tshwm sim, hauv cov txiv neej - impotence. Kev ua xua rau Torvacard qhia tau nws tus kheej zoo li urticaria, khaus, liab ntawm daim tawv nqaij, tawm pob, o. Kev kuaj ntshav tuaj yeem qhia paub txo qis hauv platelet, nce ntxiv hauv kev ua haujlwm ntawm daim siab enzymes, creatine phosphokinase, thiab kev hloov pauv hauv cov piam thaj.

Kev tswj hwm ua ke ntawm Torvacard nrog lwm cov tshuaj yuav tsum tau sab laj nrog kws kho mob txhawm rau kom zam kev phiv. Nws yog qhov txaus ntshai los ua ke ntawm atorvastatin nrog cov tshuaj uas ua rau nws cov concentration: xws li kev sib xyaw ua ke tuaj yeem ua rau rhabdomyolysis (kev puas tsuaj rau cov leeg pob txha). Yog tias tus neeg mob yuav tsum siv cov tshuaj no, tus kws kho mob tau sau ntawv rau Torvacard qhov tsawg kawg nkaus rau tus neeg mob nyob hauv kev saib xyuas tas mus li.

Kev piav qhia thiab muaj pes tsawg leeg

Cov ntsiav tshuaj yog oval, biconvex. Lawv yog txheej nrog cov xim dawb los yog yuav luag cov zaj duab xis dawb.

Ua cov tshuaj nquag lawv muaj atorvastatin calcium. Cov nram qab no tshuaj yog muaj raws li ntxiv Cheebtsam:

magnesium oxide
MCC
mis nyuj qab zib
Aerosil
croscarmellose sodium,
E 572,
low-qib hyprolose.

Lub plhaub yog tsim los ntawm cov tshuaj hauv qab no:

hypromellose,
propylene glycol 6000,
talcum hmoov
titanium dawb.

Muaj pes tsawg leeg thiab noj ntau npaum

Cov tshuaj Torvacard belongs rau cov pab pawg neeg hypolipidemic ntawm cov tshuaj, statins. Raws li cov lus piav qhia hauv cov lus qhia, nws yog ib qho inhibitor ntawm HMG-CoA reductase enzyme uas hloov cov substrate rau hauv mevalonic acid. Kev tsuj ntawm GMG-CoA-reductase tseem nyob ntev txog 21-29 teev vim yog muaj cov molecules nquag tom qab cov kab mob hepatic. Lub hauv paus ua haujlwm tseem ceeb, raws li cov lus qhia ntawm lub npe ntawm cov tshuaj (RLS) yog atorvastatin calcium. Ntu cov khoom siv muaj xws li magnesium oxide, silicon dioxide, lactose monohydrate, hydroxypropyl thiab microcrystalline cellulose.

Lub ntsiab pharmacological kev ua ntawm torvacard nyob rau hauv cov lus qhia yog txo qis LDL synthesis hauv lub siab, thiab ntxiv rau - qhov nce ntxiv hauv cov dej num ntawm kev cuam tshuam nrog cov kev txais ntawm qhov feem ntawm cov roj (cholesterol). Cov qauv kev tsim tawm ntawm cov tshuaj no yog cov ntsiav tshuaj, coated saum, hauv tsos zoo li tsiav tshuaj. Muaj nyob hauv peb txoj kev xaiv ntau npaum li cas - Torvacard 10 mg, Torvacard 20 mg, Torvacard 40 mg.

Pharmacological kev txiav txim ntawm Torvacard

Torvacard yog yeeb tshuaj uas zwm rau ib pawg tshuaj lipid-txo cov tshuaj. Qhov no txhais tau hais tias nws txo qis cov lipids hauv cov ntshav, thiab ua ntej txhua yam, txo cov roj (cholesterol).

Lipid-txo cov tshuaj tau muab faib, nyeg, mus rau ntau pawg, thiab Torvakard belongs rau ib pawg hu ua statins. Nws yog xaiv kev sib tw inhibitor ntawm HMG-CoA reductase.

HMG-CoA reductase yog ib qho enzyme uas ua lub luag haujlwm rau kev hloov pauv ntawm 3-hydroxy-3-methylglutaryl coenzyme A rau mevalonic acid. Mevalonic acid yog ib hom tshuaj tua kab mob sib ntxiv.

Tus txheej txheem ntawm kev ua ntawm Torvacard yog tias nws inhibits, uas yog, inhibits qhov kev hloov pauv no, sib tw nrog thiab thaiv HMG-CoA reductase. Nws paub txog cov roj (cholesterol), thiab triglycerides, suav nrog cov qauv ntawm lipoproteins uas tsis muaj ntau, uas tom qab ntawd tig mus rau hauv cov lipoproteins tsawg kawg, cuam tshuam nrog lawv cov receptors tshwj xeeb.

Cov tshuaj muaj zog ntawm Torvacard - atorvastatin - yog lub luag haujlwm rau txo cov roj cholesterol thiab cov lipoproteins uas tsis muaj ntau thiab tsawg, pab ua kom cov lipoprotein txais qis tsawg hauv cov nplooj siab, ntawm lub ntsej muag ntawm tes, uas cuam tshuam rau kev nrawm ntawm lawv kev txhim kho thiab tawg.

Torvacard txo kev tsim cov lipoproteins uas tsis muaj ntau ntau hauv cov neeg mob uas raug mob los ntawm ib tug kab mob xws li homozygous tsev neeg hypercholesterolemia, uas yog feem ntau nyuaj kho nrog kev siv tshuaj.

Tsis tas li, cov tshuaj pab ua rau kom muaj pes tsawg leej ntawm lipoproteins ntau lub luag haujlwm rau kev tsim cov "roj" zoo.

Pharmacokinetics thiab cov chaw muag tshuaj

Pharmacokinetics yog cov kev hloov pauv uas tshwm sim nrog cov tshuaj nws tus kheej hauv tib neeg lub cev. Qhov nws nqus tau, uas yog, kev nqus, yog qhov siab. Tsis tas li, cov tshuaj sai heev ncav cuag nws qhov kev xav ntau hauv cov ntshav, tom qab kwv yees li ib mus rau ob teev. Ntxiv mus, nyob hauv cov poj niam, tus nqi ntawm kev ncav cuag qhov siab tshaj plaws yuav nrawm dua li 20%. Hauv cov neeg muaj kev txom nyem los ntawm kev mob siab rau daim siab vim yog cawv cawv, qhov kev cia siab nws tus kheej yog 16 npaug dua siab dua li cov cai, thiab tus nqi ntawm nws qhov ua tiav yog 11 zaug.

Qhov nqus tau ntawm Torvacard yog ncaj qha ntsig txog kev noj zaub mov, vim tias nws ua rau kom nqus qis, tab sis tsis cuam tshuam rau qhov txo qis ntawm lipoprotein cov roj cholesterol kom tsawg. Yog tias koj noj tshuaj thaum yav tsaus ntuj, ua ntej yuav mus pw, ces nws cov tshuaj lom hauv cov ntshav, tsis zoo li cov tshuaj noj thaum sawv ntxov, yuav qis dua. Nws kuj tau pom tias muaj ntau dua qhov ntau ntawm cov tshuaj, nws ceev dua nws yooj yim dua.

Lub bioavailability ntawm Torvacard yog 12% vim nws txoj kev kis los ntawm cov qog ua kua ntawm lub plab zom mov thiab dhau los ntawm daim siab, qhov twg nws yog qee qhov kho.

Cov tshuaj yuav luag 100% ua txhua yam rau cov ntshav protein. Tom qab hloov kho ib nrab hauv daim siab vim kev txiav txim ntawm isoenzymes tshwj xeeb, cov metabolites nquag tau tsim, uas muaj cov nyhuv tseem ceeb ntawm Torvacard - lawv inhibit HMG-CoA reductase.

Tom qab qee yam hloov pauv hauv lub siab, cov tshuaj nrog bile nkag mus rau txoj hnyuv, dhau los ntawm qhov nws kiag li tshem tawm los ntawm lub cev. Ib nrab-lub neej ntawm Torvacard - lub sijhawm thaum lub siab ntawm cov tshuaj nyob rau hauv lub cev txo qis raws nraim 2 zaug - yog 14 teev.

Cov nyhuv ntawm cov tshuaj pom tau rau kwv yees li ib hnub vim kev ua ntawm cov metabolites ntxiv.Hauv cov zis, ib qho me me ntawm cov tshuaj muaj peev xwm kuaj pom.

Nws yog tsim nyog xav tias thaum lub sijhawm hemodialysis nws tsis ua kom pom.

Kev qhia rau kev siv tshuaj

Torvacard muaj qhov ntau ntawm cov cim.

Nws yuav tsum nco ntsoov tias cov tshuaj muaj tag nrho cov npe ntawm cov cim qhia rau kev siv, coj mus rau hauv tus account thaum sau daim ntawv yuav siv tshuaj.

Cov lus qhia rau kev siv qhia txhua tus neeg quav yeeb tshuaj.

Ntawm lawv, cov tseem ceeb muaj li hauv qab no:

Torvacard tau raug tshaj tawm kom txo cov roj cholesterol tag nrho, nrog rau cov tshuaj lipoproteins uas tsis muaj ntau, kom txo qis apolipoprotein B, kuj triglycerides, thiab nce cov nyiaj lipoprotein ntau rau cov neeg mob ntshav qab zib rau cov neeg txom nyem los ntawm heterozygous los yog thawj hypercholesterolemia, zoo li hom II lipid lipidemia Cov. Cov nyhuv yog pom tsuas yog thaum noj zaub mov.
Tsis tas li, thaum kev noj haus, Torvacard yog siv rau hauv kev kho mob ntawm tsev neeg endogenous hypertriglyceridemia ntawm plaub yam raws li Frederickson, thiab rau kev kho mob ntawm dysbetalipoproteinemia ntawm yam thib peb, nyob rau hauv uas noj tsis tau zoo.
Cov tshuaj no yog siv los ntawm ntau tus kws tshaj lij txhawm rau txo qib ntawm tag nrho cov roj (cholesterol) thiab qis lipoproteins tsawg hauv cov kab mob xws li homozygous tsev neeg hypercholesterolemia, yog tias kev noj zaub mov noj thiab lwm txoj hauv kev kho mob tsis muaj tshuaj muaj txiaj ntsig. Feem ntau raws li cov tshuaj thib ob.

Ib qho ntxiv, cov tshuaj no yog siv rau cov mob plawv thiab mob ntshav hauv cov neeg mob uas muaj kev pheej hmoo txaus rau kev mob plawv mob ntshav siab. Qhov no muaj hnub nyoog ntau dua 50 xyoos, mob ntshav siab, haus luam yeeb, sab laug ventricular hypertrophy, mob ntshav qab zib mellitus, mob raum, mob plawv, nrog rau qhov muaj mob rau cov ntshav plawv hauv cov neeg hlub.

Nws yog qhov tshwj xeeb tshaj yog nrog concomitant dyslipidemia, vim nws tiv thaiv kev txhim kho ntawm lub plawv nres, mob plawv, thiab tuag taus.

Kev phiv tshuaj los ntawm kev siv cov tshuaj

Thaum siv cov tshuaj hauv tus neeg mob, tag nrho cov kev phiv tshuaj tsis zoo yuav tshwm sim.

Qhov tshwm sim uas tshwm sim ntawm qhov tshwm sim tsis zoo yuav tsum tau txiav txim siab thaum sau ntawv tshuaj.

Coob tus ntawm cov kev mob tshwm sim thaum siv cov tshuaj ua rau categorical txiav npluav ntawm kev tswj hwm tus kheej ntawm cov tshuaj thaum kho. Cov tshuaj muaj cai raug tsuas yog kws kho mob tau sau tseg, suav ua tus yam ntxwv ntawm tus neeg mob lub cev.

Thaum siv tshuaj Torvakard, cov kev mob tshwm sim hauv qab no tshwm sim:

Lub hauv nruab nrab thiab nruab nrab lub paj hlwb - mob taub hau, kiv taub hau, qaug zog, pw tsaug zog, npau suav phem, nco puas, poob qis lossis tsis hnov qab lub cev tsis zoo, kev nyuaj siab, ataxia.
Lub plab zom mov - cem quav lossis zawv plab, ib qho kev xav ntawm xeev siab, ditch, ntau dhau lawm, kev mob siab rau thaj tsam epigastric, qhov tsis txaus siab poob qis, ua rau mob ntshav qab zib, nws tseem yog lwm txoj hauv ib puag ncig, nws mob hauv daim siab thiab mob caj pas, daj ntseg vim stagnation ntawm cov kua tsib,
Musculoskeletal system - feem ntau tsis tshua muaj mob ntawm cov leeg thiab pob qij txha, mob myopathy, mob ntawm cov leeg nqaij, rhabdomyolysis, mob nraub qaum, mob tawm tsam ntawm cov leeg nqaij,
Kev ua xua cuam tshuam - khaus thiab tawm pob rau ntawm daim tawv nqaij, urticaria, kev tsis haum tshuaj tam sim (mob anaphylactic), Stevens-Johnson thiab Lyell syndromes, angioedema, erythema,
Kev ntsuas ntsuas - nce lossis tsawg dua ntawm cov ntshav qabzib, kev nce hauv cov kev ua ntawm creatiphosphokinase, alanine aminotransferase thiab aspartate aminotransferase, nce ntxiv ntawm glycated hemoglobin,
Lwm tus - mob hauv siab, o ntawm sab hauv thiab sab saud, impotence, focal alopecia, hnyav, dav dav, tsis muaj zog platelet, txo pob txha tsis ua haujlwm.

Kev phiv tshuaj tiv thaiv tus yam ntxwv ntawm txhua qhov tshuaj ntawm cov pab pawg neeg statin kuj raug cais:

txo qis libido
gynecomastia - kev loj hlob ntawm cov qog mammary nyob hauv tus txiv neej,
cov leeg cev tsis sib haum,
Kev Nyuaj Siab
tsis tshua muaj cov kab mob ntsws nrog kev kho mob ntev ntev,
cov tsos mob ntshav qab zib.

Kev saib xyuas tshwj xeeb yuav tsum tau saib xyuas thaum noj Torvacard thiab cytostatics, fibrates, tshuaj tua kab mob thiab tshuaj tua kab mob, vim tias lawv tsis zoo tas li. Qhov no kuj siv rau mob glycosides, tshwj xeeb tshaj yog Digoxin.

Xws li cov tshuaj ntawm Torvacard yog tsim tawm xws li Lovastatin, Rosuvastatin, Vasilip, Liprimar, Akorta, Atorvastatin, Zokor.

Kev tshuaj xyuas txog cov tshuaj feem ntau yog qhov zoo, vim tias statins yog pab pawg zoo tshaj plaws ntawm cov tshuaj uas txo cov roj cholesterol.

Cov kws tshaj lij yuav tham txog cov statins hauv kev yees duab hauv kab lus no.

Pharmacological pawg

Cov tshuaj nquag xaiv thiab sib tw txwv HMG-CoA reductase, ib qho enzyme koom nrog tsim cov tshuaj steroids, suav nrog cov roj (cholesterol). Nws kuj tseem ua rau kom LDL cov neeg txais ntau ntxiv hauv daim siab, ua rau muaj kev nce siab thiab rhuav tshem LDL.

Atorvastatin txo qis LDL ntau ntau hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, uas, raws li txoj cai, tsis tuaj yeem kho nrog lwm cov tshuaj hypolipidemic.

Qhov siab tshaj plaws ntawm atorvastatin yog pom 1-2 teev tom qab noj mov. Thaum noj tshuaj thaum yav tsaus ntuj, nws qhov kev tshaj tawm yog 30% qis dua thaum sawv ntxov. Lub bioavailability ntawm cov tshuaj tsuas yog 12%, qhov no yog vim qhov tseeb tias cov tshuaj ua kom nquag plias yog metabolized hauv cov qog ua kua ntawm lub plab zom mov thiab hauv lub siab. Txog li 98% ntawm cov tshuaj khi rau cov ntshav protein. Nws yog tawm los ntawm lub cev nrog bile, ib nrab-lub neej ntawm 14 teev.

Rau cov laus

Torasemide ua ke nrog kev noj zaub mov noj yog muaj raws cai:

kom txo qhov nce ntawm tag nrho cov roj (cholesterol), qis lipoproteins tsawg, apolipoprotein B thiab triglycerides, thiab kom cov ntsiab lus ntawm lipoproteins ntau rau hauv cov neeg mob uas muaj thawj hyperlipidemia, heterozygous tsev neeg thiab tsis muaj mob hyperlipidemia, thiab sib xyaw (sib xyaw) hypercholesterolemia (hom IIa thiab IIon Fred)
nrog rau kev nce hauv triglycerides (yam IV raws Fredrickson),
nrog dysbetalipoproteinemia (hom III raws li Fredrickson),
nrog homozygous tsev neeg hypercholesterolemia kom txo qis ntawm cov roj (cholesterol) thiab cov lipoproteins uas tsis muaj ntau.

Torasemide yog tsim rau cov kab mob ntawm txoj hlab plawv mus rau cov neeg mob uas muaj kev pheej hmoo mob ntshav siab rau lub plawv - ntau dua 55 xyoos, kev quav yeeb quav cawv, ntshav siab, ntshav qab zib mellitus, mob hlab ntsha hlwb, keeb kwm ntawm mob hlab ntsha tawg, sab laug ventricular hypertrophy, protein ntau hauv cov zis, mob ntshav hauv lub plawv cov txheeb ze, suav nrog vim yog dyslipidemia. Hauv cov neeg mob no, noj cov tshuaj txo qis kev ua rau kev tuag, myocardial infarction, mob hlab ntsha tawg, rov qab pw hauv tsev kho mob vim tias angina pectoris thiab xav tau kom rov qab kho dua.

Torvacard yuav tsum tsis txhob raug txwv rau cov menyuam hluas.

Rau cev xeeb tub thiab lactating

Torvacard yog contraindicated rau cov neeg mob hauv txoj hauj lwm thiab pub niam mis. Cov tshuaj yuav tsum tsis txhob siv rau cov poj niam uas muaj hnub nyoog deev me nyuam yog tias lawv tsis siv kev tswj kom tsis muaj txiaj ntsig. Muaj kev paub txog kev yug me nyuam ntawm cov me nyuam nrog yug cov kab mob sib deev hauv rooj plaub thaum lawv cov teeb meem raug coj tawm thaum cev xeeb tub Torvacard.

Sab sij huam

Cov kev mob tshwm sim hauv qab no tej zaum yuav tshwm sim thaum kho nrog Torvacard:

mob taub hau, tsis muaj zog, kiv taub hau, ntxhov siab txog kev pw tsaug zog, uas tuaj yeem pom los ntawm kev npau suav phem, tsaug zog, pw tsaug zog, tsis nco qab lossis ua tsis tau dab tsi, kev nyuaj siab, peripheral polyneuropathy, hypesthesia, paresthesia, ataxia,
mob plab thiab mob plab, xeev siab, ntuav, raws plab, cem quav, mob plab, mob siab, mob caj pas, mob caj dab, ua rau lub plab muaj zog, ua kom tsis qab los, ua kom tsis muaj qab los noj mov,
mob leeg thiab mob pob txha, mob nraub qaum, mob hlwb myopathy, mob nqaij pob txha pob txha, mob rwj nrog rau caj pas, mob plab pob txha,
kev tsis haum tshuaj, uas pom los ntawm pob khaus, tawv nqaij ua pob khaus, urticaria, Quincke's edema, anaphylaxis, tawv nqaij ua pob, erythema multiforme exudative,
nce lossis txo hauv cov ntshav qabzib,
kev nce ntxiv hauv cov ntsiab lus ntawm glycosylated hemoglobin, cov haujlwm ntawm daim siab enzymes,
mob hauv siab
o ntawm cov tshaj plaws
erectile kawg
pathological plaub hau poob
coov hauv pob ntseg
txo cov platelet ntau ntau hauv cov ntshav,
theem ob lub raum tsis ua haujlwm
hnyav
qaug zog thiab malaise.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog rau kev tswj hwm tib txhij ntawm atorvastatin thiab cyclosporine, fibrates, erythromycin, clarithromycin, immunosuppressants thiab antimycotics ntawm pab pawg azole, nicotinic acid thiab nicotinamide, tshuaj uas tiv thaiv metabolism, nrog kev koom tes ntawm 3A4 CYP450 isoenzymes, thiab / lossis thauj cov tshuaj, thiab qhov pheej hmoo ntawm myopathy. Yog li ntawd, thaum xws li kev sib koom ua ke yog qhov tsis dhau, koj yuav tsum ntsuas qhov txaus ntshai thiab cov txiaj ntsig ntawm nws. Cov neeg mob uas tau txais kev kho mob sib xyaw ua ke yuav tsum yog kev saib xyuas tas li thiab, yog tias muaj cov kev ua si hauv lub cev ntau dhau los yog pom tias muaj tus mob myopathy pom, Torvacard yuav tsum tsis ua mus ntxiv.

Colestipol txo qis ntawm cov tshuaj atorvastatin, tab sis lipid-txo cov tshuaj ntawm cov kev sib txuam no yog siab tshaj qhov ntawm txhua qhov ntawm cov tshuaj cais tawm.

Atorvastatin nce cov nyhuv ntawm cov tshuaj uas txo qis qib ntawm cov tshuaj hormones endogenous steroid.

Thaum sau tshuaj rau atorvastatin hauv kev noj tshuaj txhua hnub ntawm 80 mg ib txhij nrog lub qhov ncauj tiv thaiv raws li norethindrone thiab ethinidestraliol, ib qho kev nce ntxiv ntawm cov concentration ntawm cov tshuaj tiv thaiv hauv cov ntshav tau pom.

Thaum noj atorvastatin hauv kev noj tshuaj txhua hnub ntawm 80 mg nrog digoxin, ib qho kev nce ntxiv hauv kev saib xyuas ntawm tus mob glycoside tau pom.

Cov lus qhia tshwj xeeb

Ua ntej noj Torvacard, kev txo qis roj yuav tsim nyog sim noj nrog lub cev, ua kom lub cev muaj zog, poob phaus hauv cov neeg mob rog thiab kev kho mob ntawm lwm tus kab mob.

Tawm tsam keeb kwm ntawm kev kho mob, kab mob siab yuav ua haujlwm tsis zoo, yog li nws tus mob yuav tsum kuaj ua ntej pib Torvacard, 6 thiab 12 lub lis piam tom qab pib kho, tom qab lwm qhov nce ntxiv hauv tshuaj, thiab tseem tsis tseg, piv txwv li, ib zaug txhua rau lub hlis. Thaum kho, kev nce siab hauv kev ua si ntawm daim siab enzymes yuav pom, tshwj xeeb tshaj yog nyob rau thawj 3 lub hlis ntawm kev kho mob, tab sis yog tias cov ntsuas no tau dhau los ntau tshaj 3 zaug, koj yuav tsum yog txo cov tshuaj atorvastatin lossis tsum tsis noj.

Tsis tas li, kev kho mob yuav tsum tau txiav yog tias muaj cov cim ntawm myopathy, qhov tseem muaj kev pheej hmoo rau lub raum tsis ua haujlwm vim rhabdomyolysis, xws li ntshav qis, mob hnyav, mob hnyav, phais mob hnyav, mob, tsis nco qab, cuam tshuam ntawm lub cev, ua kom mob endocrine.

Tawm tsam keeb kwm ntawm kev kho mob, cov qib ntawm cov piam thaj hauv lub cev yuav nce ntxiv, hauv qee cov neeg mob, qhov tshwm sim ntawm ntshav qab zib mellitus yog ua tau, uas yuav tsum tau teem sijhawm ntawm cov piam thaj hauv cov tshuaj.

Cov tshuaj tsis cuam tshuam rau lub peev xwm ntawm kev tsav tsheb.

Cia rau cov neeg mob

Torvacard yuav tsum khaws cia kom tsis ncav cuag cov menyuam yaus tau 4 xyoos txij li hnub tsim cov tshuaj. Cov tshuaj no tau faib tawm los ntawm lub khw muag tshuaj raws li kws kho mob tau sau tseg, yog li ntawd lawv tsis raug txwv rau tus kheej.

Tus tub sab. Qhov no yog hom tshuaj Indian uas muaj nyob hauv cov ntsiav tshuaj oblong. Lawv, tsis zoo li Torvacard ntsiav tshuaj, muaj kev pheej hmoo, uas yooj yim rau cov neeg mob uas tsis tuaj yeem nqos tshuaj tag nrho.
Cov Atomax Cov tshuaj yog tsim los ntawm lub tuam txhab Indian HETERO DRUGS Limited. Nws muaj nyob rau hauv puag ncig, biconvex ntsiav tshuaj nrog kev pheej hmoo. Lub txee lub neej ntawm cov tshuaj yog 2 xyoos.
Atorvastatin. Cov tshuaj yog tsim los ntawm ntau lub tuam txhab Lavxias. Nws tus nqi qis dua li ntawm Torvacard, tab sis raws li tom kawg, koj tuaj yeem paub meej txog qhov sib txawv ntawm cov tshuaj hauv tsev. Lub txee lub neej ntawm Atorvastatin tej zaum yuav luv dua li ntawm Torvacard, piv txwv li, nws yog 3 xyoo rau cov tshuaj tsim los ntawm Biocom CJSC.

Koj tuaj yeem coj cov analogue hloov chaw Torvacard tsuas yog tom qab sab laj tus kws kho mob.

Tus nqi ntawm Torvacard yog qhov nruab nrab ntawm 680 rubles. Tus nqi li ntawm 235 txog 1670 rubles.

Siv thaum cev xeeb tub

Cev xeeb tub nrog kev siv cov statin no yog kev sib deev. Raws li cov lus qhia, cov tshuaj tseem tsis tau sau lub sijhawm pub niam mis, vim qhov tseeb tias nws tsis tau meej meej meej tias seb puas muaj kev tivthaiv, atorvastatin, kis mus rau hauv niam mis.

Raws li cov lus qhia, nws tsis yog kws kho nyob rau hauv kev kho mob hauv tsev kho mob vim tias tsis muaj pov thawj hauv paus rau kev thov hauv kev lag luam no.

Kev cuam tshuam nrog lwm yam tshuaj

Txoj kev pheej hmoo ntawm cov tsos thiab kev loj hlob ntawm myopathy thaum sau tshuaj lipid-txo cov tshuaj uas txo cov tsim ntawm cov roj cholesterol nce nrog qhov kev sib txuam nrog ntau ntawm cov tshuaj. Hauv tshwj xeeb, fibrates, antimicrobials (azole derivatives), cyclosporine, thiab ib tug xov tooj ntawm lwm yam tshuaj. Cov lus qhia muaj cov npe ntawm cov cuab yeej, cuam tshuam nrog uas muaj tus lej ntawm cov nta:

Nrog lub sijhawm sib law liag ntawm torvacard nrog phenazone lossis warfarin - Tsis pom muaj tsos mob tshwm sim loj tsawv rau pom.
Nrog synchronous thawj coj ntawm cov tshuaj, nyiam cyclosporine fibrates (gemfibrozil thiab lwm yam tshuaj ntawm pab pawg no), cov tshuaj tiv thaiv kab mob, cov tshuaj tua kab mob azole derivatives, cov tshuaj uas inhibit metabolism hauv nrog CYP450 isoenzyme 3A4, lub plasma concentration ntawm Torvacard nce. Soj ntsuam kev soj ntsuam ntawm cov neeg mob thiab, yog tias tsim nyog, kev tswj hwm tshuaj ntawm tsuas yog hauv kev pib siv pom zoo.
Nrog rau kev siv nrawm nrog Torvacard hauv ib qho nyiaj ntawm 10 mg rau ib hnub thiab azithromycin nyob rau hauv ib qho nyiaj ntawm 500 mg rau ib hnub, AUC ntawm thawj ntawm lawv nyob hauv ntshav tseem tsis tau hloov pauv.
Nrog rau cov kev siv sib luag ntawm cov statin no thiab cov tshuaj tua kab mob, uas muaj cov hydroxyxides ntawm magnesium thiab aluminium, cov statin AUC hauv cov ntshav txo qis yuav luag 30-35%, tab sis cov kev kho mob tsis tau hloov thiab qib qis dua ntawm LDL hauv cov ntshav ntshav tsis hloov, txawm li cas los xij, tus kws kho mob xav tau kev tswj hwm.
Kauj ruamCov. Ib yam li cov statins uas tau kawm txog niaj hnub no, nws tseem yog ib qho lipid-txo cov khoom uas yog pawg ntawm anion-txauv resins. Nrog rau cov ntawv thov kev sib raug zoo, qhov kev kub siab hauv lub plasma ntawm Torvacard poob qis los ntawm yuav luag ib lub hlis twg, tab sis cov txiaj ntsig kev soj ntsuam tag nrho los ntawm kev pib siv cov tshuaj synchronously tau siab dua txhua ntawm lawv cais.
Qhov ncauj txwv tsis pub muajCov. Cov kev tswj hwm thaum uas tig mus ua ke ntawm kev txiav txim siab statin hauv qhov siab (80 milligrams) nrog cov tshuaj no ua rau pom qhov nce hauv qib ntawm cov tshuaj hormonal tshuaj. Raws li cov lus qhia, AUC ntawm ethinyl estradiol nce txog 20%, thiab norethisterone los ntawm 30%.
DigoxinCov. Kev sib xyaw nrog digoxin ua rau qhov tseeb tias feem pua ntawm cov ntshav torvacard nce ntxiv txog 20%. Cov neeg mob tau txais digoxin ntau ntxiv nrog statin ntawm qhov ntau tshaj koob (80 milligrams - ntau kawg, tswj hwm los ntawm cov lus qhia) yuav tsum tau saib mus tas li.

Tus nqi tshuaj

Tus nqi nruab nrab ntawm cov tshuaj ntawm cov khw muag tshuaj muaj raws li nws cov koob tshuaj thiab cov tshuaj hauv lub ntim. Hauv Lavxias tus nqi nruab nrab rau Torvakard hauv lub tebchaws yog:

Torvacard 10 mg - txog 240-280 rubles rau 30 ntsiav tshuaj, rau 90 ntsiav tshuaj koj yuav tsum tau muab tus nqi nyob rau hauv thaj tsam ntawm 700-740 rubles.
Torvacard 20 mg - txog 360-430 rubles rau 30 ntsiav tshuaj thiab 1050 - 1070 rubles rau 90 ntsiav tshuaj, ntsig txog.
Torvacard 40 mg - txog 540 - 590 rubles rau 30 ntsiav tshuaj thiab 1350 - 1450 rubles rau 90 daim.

Hauv Ukrainian Cov tshuaj khw rau Torvacard hauv cov chaw muag tshuaj yog raws li nram no:

Torvacard 10 mg - txog 110-150 UAH rau 30 ntsiav tshuaj, rau 90 ntsiav tshuaj koj yuav tsum tau muab tus nqi hauv thaj tsam ntawm 310 - 370 UAH.
Torvacard 20 mg - txog 90 - 110 UAH rau 30 ntsiav tshuaj thiab 320 - 370 UAH rau 90 ntsiav tshuaj, ntsig txog.
Torvacard 40 mg - tus nqi sib txawv ntawm 220 txog 250 UAH rau 30 ntsiav tshuaj.

Kev cai tswj hwm tus nqi yog nyob ntawm lub teb chaws thiab cov chaw tsim khoom, nyob ntawm cov yam ntxwv ntawm kev lag luam kws tshuaj, raws li kev cai nqe hauv cheeb tsam.

Cov Lus Cim Torvakard

Torvacard - cov tshuaj uas tau ua pov thawj nws tus kheej, qhia tau tias qhov kuaj mob tau zoo thiab tsim nyog tus nqi - pheej yig hauv nqe. Txawm li cas los xij, nyob hauv qee kis (qee tus mob tsis nco qab, hloov pauv ntawm cov ntawv kho mob, hloov pauv ntawm tus neeg mob lub sijhawm), nws yuav tsum xaiv ib qho analogue tsis txhob siv lub teeb.

Muaj cov hloov chaw nrog tib yam tshuaj muaj yees hauv cov lus qhia, raws li nrog Torvakard - AtorvastatinCov. Cov no suav nrog Atokor, Atoris, Liprimar, Torvazin, Tulip, Livostor.

Ntxiv rau lawv, cov kws kho mob tshwj xeeb muaj peev xwm xaiv tau cov neeg ua liaj ua teb. cov pab pawg kuj muaj statins. Cov no suav nrog cov tshuaj xws li Acorta, Rosuvastatin, Krestor, Rosucard, Rosart, Lipostat, Roxer, Simgal thiab lwm yam.

Kev Siv Tshuaj Xyuas

Ntawm cov kws kho mob, hais txog torvakard kev txheeb xyuas tshwj xeeb tshaj yog hais lus txhawb. Nws feem ntau pom tshwm hauv kev teem caij rau hypercholesterolemia ntawm txawv keeb. Ntau xyoo dhau los, cov tshuaj no tau ua pov thawj hauv kev coj ua.

Zhilinov S.A. Endocrinologist, Ufa: “Kuv tau siv sijhawm rau kuv cov neeg mob rau qee lub sijhawm. Kuv ib txwm pom lub txiaj ntsig ruaj khov nrog qhov tsawg kawg ntawm kev sib txuam lossis cov kev mob tshwm sim. Nws ua tau zoo heev hauv kev kho cov mob uas muaj cov roj cholesterol siab. Tsis tas li ntawd, hauv kev tiv thaiv cov mob ischemia, nws kuj tseem yog lub luag haujlwm tseem ceeb. Thiab ntawm tus nqi nws yeej muaj rau yuav luag txhua tus neeg mob. ”

Zoo li cov kws kho mob, cov neeg mob tseem hais lus txog cov tshuaj no. Thaum piv nrog lwm cov statins nrov, tus nqi thiab muaj ntawm cov tshuaj txaus nyiam heev.

Vasilenko S.K., tus tsav tsheb tavxij, hnub nyoog 50 xyoo, Kerch: “Kuv muaj cov roj (cholesterol) hauv kuv cov lus hais rau rau lub xyoo tas los. Kuv tau mus rau hauv thaj chaw kho mob, tus kws kho mob hauv zos tau qhia Torvakard rau kuv. Thaum xub thawj kuv xav tias kuv tau siv nyiaj tas li, tab sis tom qab ntawd kuv nyeem cov lus qhia ntawm cov tshuaj, mloog cov lus qhia los ntawm tus kws kho mob thiab pom tau tias cov nyhuv tsis muaj txiaj ntsig, tab sis maj mam tshwm sim. Thiab tom qab ob lub lis piam, Kuv kuv tus kheej tau hloov pauv zoo hauv kuv li kev noj qab haus huv. Tam sim no kuv tsis muaj cov kev tsis txaus siab pom tseeb, Kuv xav tias kuv tus kheej muaj kaum xyoo yau dua. "

Chegoday E.A. 66 xyoo, Voronezh: “Txij li thaum kuv tseem hluas kuv muaj teeb meem mob ntshav siab. Ua ntej noj torvacard, Kuv haus lypimar - txiav txim los ntawm cov lus qhia, lawv muaj yuav luag tib yam. Tab sis tus nqi rau lypimar yog tam sim no tom, yog li tus kws kho mob pom zoo tias kuv yuav hloov nws nrog cov tshuaj pheej yig dua. Kuv tus kheej tsis pom ib qho txawv, tsis muaj kev phiv los ntawm daim ntawv teev loj hauv cov lus qhia, Kuv tsis pom pom ntawm cov tshuaj lossis qhov no. Nws tsuas yog ib qho tu siab tias cov tshuaj no yuav tsum haus tag nrho kuv lub neej. "

Panchenko Vera, 39 xyoo, p. Antonovka: “Kuv txiv muaj mob ntshav qab zib hom 2 ntev los lawm, ua ntej kho, qhov ntau ntawm cov piam thaj hauv cov ntshav ntawm lub plab khoob tau txog 8-9. Nws muaj qhov ntau dhau ntawm lub cev nyhav, thiab raws li kws kho mob tau hais, yog vim li cas cov roj (cholesterol) thiaj li poob mus rau hauv kev ntsuas. Hauv tsev kho mob hauv nroog, peb tau hais qhia kom zoo, ntxiv rau txhua qhov kev kho peb tus mob, haus 20 milligrams ntawm torvacard ib hmos, raws li cov lus qhia. Nws muab tawm los ua qhov yooj yim heev - koj yuav tsum tau haus nws tsuas yog ib hnub ib zaug. Tsuas yog qhov koj xav tau, vim hais tias txiv muaj hnub nyoog yuav luag 70 xyoo thiab nyob rau hauv nws lub xyoo nws nyuaj rau nws nco qab txhua yam tshuaj. Ntxiv mus, cov lus qhia tau hais tias kev noj tshuaj tsis yog nyob ntawm cov zaub mov - qhov no tau yooj yim muab rau leej txiv cov ntshav qab zib. Hauv thawj lub hlis thawj zaug, thaum peb pib haus cov tshuaj no, muaj kev txo qis hauv cov roj uas txhaws taus, thiab tam sim no txhua yam zoo rau nws, nws yog qhov qub».

Raws li koj tuaj yeem pom, txiav txim los ntawm kev tshuaj xyuas ntawm ob tus kws kho mob thiab lawv cov neeg mob, xaiv cov lipid-txo cov tshuaj - Torvakard - muaj cov kev ua tau zoo heev thiab yog qhov tshwm sim ntau hauv kev kho mob. Tsis tas li feem ntau muaj kev tshuaj xyuas txog qab ntxiag tsim nyog tus nqi ntawm cov statin no. Nws yuav tsum raug coj mus rau hauv tus account thiab nco ntsoov tias nws yog qhov tsim nyog los sau tshuaj torvacard tsuas yog tom qab kev kuaj xyuas tag nrho thiab sab laj nrog cov kws tshaj lij txoj cai, ua raws nws cov lus qhia nruj ntawm tus kheej.