Kev kho mob ntshav qab zib hom 1 hauv israel

antagonist B. cepacia AB 1934 thiab 8 ntau yam ntawm B. thailandensis 295, uas tau cim los ntawm qhov poob ntawm qhov tsis kam tiv thaiv kanamycin, tab sis khaws cov tshuaj tiv thaiv chloramphenicol thiab tib lub sijhawm ua kom tau txais kev pabcuam, uas qhia tias kev sib xyaw ntawm Tn9 rau hauv lub tshuab hluav taws xob. Kev txiav txim siab ntawm lawv cov khoom noj khoom haus xav tau raws li Holliday cov txheej txheem qhia tau hais tias kev sib koom ua ke ntawm kev hloov pauv hauv kev hloov pauv rau kev tos ntawm cov kab muag lossis glutamine. Ua haujlwm dhau sijhawm, ib feem ntawm cov StK clones tau hloov mus rau prototrophy, uas tej zaum vim yog qhov kev hloov ntawm transposon raws tus chromosome.

Qhov kev ua haujlwm no tau qhia txog qhov ua tau thiab qhov xwm txheej ntawm kev sib kis thaum lub sijhawm sib xyaw ua ke ntawm plasmid Rts1 :: Tn9 los ntawm E. coli KS 707 (Rts1 :: Tn9) rau B. cepacia AB 1934 thiab B. thailandensis 295 hom muaj ntau zaus ntawm 6 × 10-8 ib tus neeg tau txais kev pabcuam. Cov. Hloov kho txoj siv nrog plasmid tshuaj tua kab mob tiv thaiv tau txais, qhov kev txiav txim siab uas tau txais txiaj ntsig zoo hauv tus tswv tsev tshiab, nce qhov kev cuam tshuam ntawm cov kab mob mus rau kanamycin thiab chloramphenicol los ntawm 3-6 zaug. Transconjugates qhia tau txo qis rau thaum kawg rau kub hamsters thiab cytopathogenicity rau P aculeata. Qhov tseem ntawm kev sib xyaw Tn9 rau hauv lub chromosome tau qhia.

Yog li, peb tuaj yeem xaus tias plasmid Rts1 :: Tn9, ntxiv rau plasmids P-1 ntawm pab pawg sib raug zoo, tuaj yeem siv rau kev tshawb fawb keeb ntawm burkholder.

1. Voronina O. L., Chernukha M. Yu., Shaginyan I.A. et al. // Molecular Genetics, Microbiology thiab Virology. - Xyoo 2013. - No. 2 - S. 22-30.

2. Kalinkina E.V., Ageeva N.P., Merinova O.A. et al. // Cov teeb meem tshwj xeeb tshaj yog kis mob. - 2008. - Zaj 96 - S. 32-35.

3. Molchanova E.V., Ageeva N.P. Patent rau qhov kev tsim tshiab No. 2485182 Ib txoj hauv kev los ntsuas tus kheej virulence ntawm cov kab mob pathogenic burkholderia raws cytopathogenicity / hnub tim 23.01.2012.

4. Morozova M.V., Merinova L.K., Seimova I.K. et al. // Cov ntawv xov xwm ntawm Volgograd Scientist Center ntawm RAMS. - 2006. - No. 1. - S. 38-40.

5. Peters M. K., Shipovskaya N. P., Merinova L. K. // Microbiological phau ntawv xov xwm. - 1983. - T 45. - V. 3. - S. 11-14.

6. Coenye T., Vandamme P. // Chaw. Microbiol. - 2003. - Vol. 5. - P 719-729.

7. Deshazer D. // FEMS Microbiol. Ntawv tso. - 2007. - Vol. 277 (1). - P 64-69.

8. Murata T., Ohnishi M., Ara T., li al. // J. Bacteriol. - 2002. - Vol. 184. - P 3194-3202.

Molchanova Elena Vladimirovna - K. b. n.,.

nrog n nrog chaw sau ntawv FKUZ Volgograd Kev Tshawb Fawb Kev Tshawb Fawb Plague Lub koom haum ntawm Rospotrebnadzor, tus pabcuam ntawm Lub Tsev Haujlwm ntawm Molecular Biology thiab Genetics, Volgograd State Medical University e-mail: [email protected]

YEEM INSULINS IN TSHUAJ LOS NTAWM KEV MENYUAM MENYUAM DIABETES MELLITUS HOM I: "RAU" THIAB "Tawm tsam"

N. Yu. Otto, G. R Sagitova, M. Ya. Ledyaev

Lub Tsev Kho Menyuam Menyuam Hauv Cheeb Tsam muaj npe tom qab N.N. Silishcheva, Astrakhan,

Astrakhan Xeev Medical Academy,

Volgograd State Medical University

Ib qho ntawm ob tog los txhim kho lub neej zoo ntawm cov neeg mob yog suav tias yog kev xaiv cov tshuaj insulin kom tsim nyog. Raws li peb qhov kev soj ntsuam hauv tus kheej, cov hau kev rau kev tawm tsam ntawm kev siv tshuaj insulin yog nce, nyob ntawm seb hom tshuaj, hnub nyoog ntawm tus menyuam, thiab txaj pw hauv tsev kho mob.

Cov ntsiab lus: cov menyuam yaus, hom I ntshav qab zib mellitus, kev kho tshuaj insulin.

PROS THIAB COV TSWV YIM NTAWM KEV SIV COV QAUV INSULIN NYOB RAU kev kho mob ntawm cov menyuam nrog yam I DIABETES

N. Yu. Oio, G. R. Sagitova

Tsim nyog xaiv cov tshuaj insulin yog suav tias yog ib qho tseem ceeb hauv kev txhim kho cov neeg mob lub neej. Peb tawm tswv yim rau kev siv rau kev siv tshuaj insulin raws li hom tshuaj, hnub nyoog ntawm tus menyuam raws li peb cov kev tshawb fawb hauv kev paub.

Cov ntsiab lus: cov menyuam yaus, hom I ntshav qab zib, kev kho tshuaj insulin.

Kev kawm txog cov teeb meem cuam tshuam, cuam tshuam rau lub teb chaws thiab lub teb chaws txoj haujlwm 1, 2. Kev mob ntshav qab zib sai, tshwj xeeb tshaj yog nyob hauv cov menyuam yaus, tau paub tias yog tus kabmob.

Qhov Xwm Txheej 4 (48). 2013 57

insulin tsis muaj zog txaus. Yog li ntawv hloov tshuaj insulin thiaj kho tau yam mob ntshav qab zib hom I hauv menyuam yaus nkaus xwb. Txij li xyoo 2012, Daim Ntawv Teev Cov Tshuaj Tseem Ceeb thiab Cov Tshuaj Tseem Ceeb tau siv, tau pom zoo los ntawm Tsab Cai ntawm Tsoomfwv Lavxias ntawm Lub Kaum Ob Hlis 7, 2011 No. 2199-r, uas suav nrog insulin. Qhov kev xaiv kho kom zoo tshaj plaws rau cov ntshav qab zib hom I yog suav tias yog kev siv tshuaj insulin ntau ntxiv - ib qho kev siv ntau txoj kev txhaj tshuaj ntawm cov tshuaj insulin uas ua rau muaj kev tawm tsam ntawm insulin. Cov kev kho mob yog subcutaneous thawj coj ntawm ob hom tshuaj insulin. Ntau zaus tshaj qhov no yog siv cov insulin luv luv (Actrapid lossis Humulin Tsis tu ncua) lossis ultrashort (NovoRapid lossis Humalog), uas tau noj ua ntej noj zaubmov tseem ceeb (ib hom ntawm cov qog ntawm cov zaub mov zais cia tshwm sim) thiab nruab nrab ntev insulin (Protofan, Humulin NPH) lossis ua haujlwm ntev (Lantus) ( qog ntawm lub ntsiab lossis qhov tob zais cia ywj pheej ntawm cov khoom noj). 1-2 zaug hauv ib hnub 3, 5 qhia txog Dr. Endocrinologist, xyaum kws kho mob tau hnov ​​ntau yam txog qhov zoo ntawm cov "tshiab" insulins dhau "qub", siv zog ua kom tiav ntawm thawj tus tib neeg tsim kho (biosynthetic) insulins, xws li Actrapid thiab Protofan (tuam txhab Novo Nordisk, Tebchaws Denmark), Humulin Tsis Txaus thiab Humulin NPH, (Eli Lilly, Asmeskas). Kev hloov mus rau kev siv insulins ntawm tib lub tuam txhab, tab sis ntawm ultrashort kev txiav txim siab (tib neeg analogues) - insulin Aspart (lag luam lub npe Novorapid) thiab insulin Lizpro (Humalog), yog qhov tseeb los ntawm qhov tseeb tias lawv tau ua yeeb yam ceev. Ntawm cov insulins niaj hnub ntev hauv kev kho mob siv, Glargin (Lantus) (Aventis, Lub Tebchaws Yelemees) thiab Detemir (Levemir) (Novo Nordisk, Denmark) tau siv ntau hauv kev kho mob. Qhov kom zoo ntawm ultrashort insulins yog tias tsis tas yuav tiv thaiv lub sijhawm ua ntej noj mov, cov neeg mob hloov lub cev sib xyaw thiab sijhawm noj mov, thiab qhov no yog qhov tseem ceeb heev los ntawm qhov pom ntawm kev ntsuas lub neej zoo ntawm cov neeg mob. Lantus yog qhov tshuaj insulin 24-teev ib zaug ib hnub, qhov txawv ntawm cov tshuaj nruab nrab (Protofana thiab Humulin NPH), uas tau txhaj ob zaug (sawv ntxov thiab yav tsaus ntuj), uas, dhau los, txo cov naj npawb ntawm cov hno. Tsuas yog qhov tsis zoo ntawm cov insulins niaj hnub no yog tus nqi, uas, piv txwv li, ntau dua tus nqi ntawm Actrapid thiab Protofan thiab Humulin los ntawm ntau dua 3 zaug.

Txoj kev kawm txog cov yam ntxwv ntawm cov tshuaj insulin, suav txog ntau hnub siv sijhawm los ntawm cov neeg mob ntshav qab zib hom I hauv tsev kho mob thiab qhov nruab nrab txhua hnub koob tshuaj insulin nyob ntawm seb muaj hnub nyoog li cas.

Kev soj ntsuam ntxaws ntawm cov ntaub ntawv kho mob (daim ntawv 112, daim foos 003 / y) ntawm 144 cov menyuam thiab cov tub ntxhais hluas tau ua tiav

ntawm hom I mob ntshav qab zib mellitus uas tau tshuaj xyuas thiab kho ntawm Endocrinology Department xyoo 2012. Cov kev kho mob feem ntau siv yog insulin ntawm "tiam tshiab": cov kev ua kom zoo dua Humalog lossis Novorapid (70%) nrog cov tshuaj insulin Lantus ntev (50%) thiab hauv 1/5 me nyuam yaus ua ke nrog Levemir. Cov insulins "laus", xws li Humulin - Li Niaj Zaus thiab NPH. ntau tshaj li ib feem peb ntawm cov menyuam tau txais, thiab Actrapid thiab Protofan 4% ntawm cov menyuam yaus. Feem ntau, kev sib xyaw ua ke ntawm luv-ntev thiab nruab nrab-ntev insulins tau siv - Actrapid + Protofan, Humulin Tsis Tu ncua + Humulin NPH, ultrashort thiab ntev ntev insulin-Humalog + Lantus thiab Novorapid + Levemir (95%). Tsis tshua muaj siv: Humulin Tsis tu ncua + Lantus, Actrapid + Lantus, Actrapid + Levemir, Novorapid + Lantus (5%), uas cuam tshuam nrog kev npaj cov tshuaj insulin ntawm qhov chaw nyob. Hauv cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog 11-17 xyoo, qhov tshiab tshaj ntawm insulins - Humalog thiab Lantus - tau siv ntau dua, hauv cov menyuam yaus ntawm tsev kawm ntawv hnub nyoog 7-10 xyoo - Novorapid thiab Levemir, hauv cov menyuam yaus - Humulin Tsis tu ncua thiab Humulin NPH. Xws li kev xaiv ntawm cov tshuaj insulin hauv cov pab pawg hnub nyoog yau yog tshwm sim los ntawm kev muab khoom zoo ntawm HumaPen thiab Novo-Pen insulin syringe cwjmem nrog kev txhaj tshuaj me me ntawm 0.5 units. Kev tsom xam qhov taw qhia ntawm cov naj npawb ntawm cov txaj pw thaum kho, peb tau sau tseg tias thaum siv ultra-luv thiab luv luv ua yeeb yam insulins (Humalog, Novorapid, Actrapida, Humulin tsis tu ncua), qhov tsawg tshaj plaws nyob hauv txaj tau sau tseg thaum kho nrog Novorapi-tsev - nruab nrab pw hnub 16.6 qhov loj tshaj plaws - nrog kev kho mob ntawm Humalog - 18.5. Kev pw lub txaj nruab nrab luv tshaj plaws tau pom thaum siv Humalog hauv ib pab menyuam yaus hnub nyoog 14-14 xyoo, Novorapida - hauv pab pawg hnub nyoog 4-6 xyoo, Humulin tsis tu ncua - hauv ib pawg 4-6 xyoo, Actrapida rau cov neeg hluas hnub nyoog 15-17 xyoo. Thaum siv cov insulins ntawm lub sijhawm nruab nrab thiab kev ua haujlwm ntev (Protofan, Humulin NPH, Lantus, Levemir), kev nyob tsawg tshaj plaws tau sau tseg nrog Protofan kev kho mob - nruab nrab ntawm lub txaj-hnub yog 16,2, thiab qhov loj tshaj nrog kev kho mob Lantus - nruab nrab ntawm lub txaj-hnub yog 18.8. Lub txaj luv tshaj plaws-hnub thaum siv Lantus tau sau tseg hauv pawg 7-10 xyoo, Levemira - hauv pawg 4-6 xyoo thiab 15-17 xyoo, Protofana - hauv pab pawg ntawm 15-17 xyoo, Humulin NPH - hauv pawg 4-6 xyoo. Cov hnub pw ntev tshaj plaws yog tus yam ntxwv rau lub hnub nyoog ntawm 11-14 xyoo (uas muaj peev xwm sib txuas nrog lub sijhawm ntawm cov tshuaj hormonal load) thiab yog 20.2 hnub pw. Hauv kev kho mob nrog ultrashort insulins, qhov nruab nrab ib hnub ntawm 15 (Novorapid) yog 17 units (Huma log) thiab rau cov "qub" tiam ntawm luv luv ua yeeb yam insulin, qhov nruab nrab txhua hnub koob tshuaj insulin yog 15.8 (Humulin Tsis Txaus) - 17.7 units (Actrapid). Cov "insulins" ua yeeb yam ntev ntev tseem tsis tau muaj txiaj ntsig zoo: qhov ntsuas nruab nrab txhua hnub ntawm 12.3 (Levemir) yog 13,1 units (Lantus), thiab insulin "qub".

Qhov Xwm Txheej 4 (48). 2013

qhov nruab nrab ntawm nruab nrab qhov nruab nrab ib hnub ib nrab yog 12.7 (Humulin NPH) yog 13.9 units (Protofan). Rau tag nrho cov insulins, ib yam yog cov yam ntxwv: qhov koob tshuaj nce rau hauv qhov sib piv rau lub hnub nyoog, muaj qhov "dhia" nce ntxiv ntawm cov tshuaj insulin los ntawm 1.5-3 zaug, uas poob rau lub hnub nyoog 7-14 xyoo, piv nrog cov menyuam pib kawm. Rau cov menyuam yaus hnub nyoog (1-3 xyoos), qhov tsawg kawg yog nruab nrab txhua hnub rau txhua qhov insulin (4-8 units), thiab qhov siab tshaj plaws - rau lub hnub nyoog 15-17 xyoo (17-28 units). Thaum siv insulins ultra-luv-ua yeeb yam thiab luv luv ua yeeb yam insulins (Humalog, Novorapid, Aktrapid, Humulin Tsis Txaus), qhov tsawg tshaj plaws nruab nrab txhua hnub ntawm insulin yog pom nyob hauv Humalog thaum 1-3 xyoo ntawm lub neej (5.1 units), Novorapid thaum 7-10 xyoo (13 , 2 units), Actrapida hauv 7-10 xyoo (14.0 units). Thaum siv cov tshuaj insulins ntawm cov tshuaj nruab nrab thiab ua ntev ntev (Protofan, Humulin NPH, Lantus, Levemir), qhov qis tshaj plaws ntawm ib hnub ib zaug tau raug soj ntsuam nyob rau hauv Humulin NPH hauv 1-6 xyoo ntawm lub neej - 4.5 ntsuas. Thaum muaj hnub nyoog 7-10 xyoo, koob tshuaj Lantus thiab Levemir yog 1.5 npaug tsawg dua thaum siv cov tshuaj insulins nruab nrab (Protofan thiab NPH). Peb ntseeg tias thaum muaj hnub nyoog ntawm 11-14, nws yog qhov zoo dua los muab qhov zoo rau Lantus, txij li nws muaj qhov koob tshuaj qis tshaj thaum siv (13,2 units). Thaum 15-17 xyoo, cov koob tshuaj qis tshaj thaum siv Protofan (17 units) thiab Lantus (17.8 units).

1. Nws tsis muaj qhov kev txo qis tseem ceeb ntawm lub sijhawm nyob hauv txaj thiab qhov txo qis hauv nruab nrab txhua hnub thaum siv cov insulins "tshiab".

2. Tsom ntsoov rau qhov tshwm sim ntawm kev kho mob ntawm lub txaj-hnub tus nqi thiab kev noj tshuaj insulin txhua hnub, peb xav kom siv cov kev pom zoo hauv qab no: Humalog tuaj yeem pom zoo thaum muaj hnub nyoog ntawm 1-3 xyoos thiab 11-14 xyoo, Novorapid thaum 4-10 xyoo, Humulin Tsis tuaj yeem pom zoo hauv 4-6 xyoo, NPH thaum muaj hnub nyoog 1-6 xyoo, Leva-ntiaj teb 4-10 thiab 15-17 xyoo, Lantus thaum muaj hnub nyoog 7-17 xyoo, Actrapid thaum muaj hnub nyoog 7-10 xyoo, Actrapid thiab Protofan (tsis zoo rau lub tswv yim niaj hnub) 15-17 xyoo Cov.

1. Dedov I.I., Kuraeva T. L., Peterkova V. A., Shcherba-cheva L. N. Mob ntshav qab zib mellitus hauv cov menyuam yaus thiab cov hluas. - M.: Universum Kev Tshaj Tawm, 2002 .-- 203 p.

2. Dedov I.I., Melnichenko G.A. Lub zog tu xyuas. Endocrinology. - M .: Litterra, 2007 .-- 85 p.

3. Dedov I.I., Peterkova V.A., Kuraeva T. L. Lavxias pom zoo txog kev kho mob ntshav qab zib hauv cov menyuam yaus thiab cov hluas. // Farmateka. - 2010. - Zaj 3. - S. 7-10.

4. Cov txheej txheem los kho tshwj xeeb rau cov neeg mob ntshav qab zib mellitus // Mob Ntshav Qab Zib. - 2011. - Zaj 3 (txuas ntxiv).

5. Miskas Pab Koom Tes Sib Koom Tes. Cov Qauv Ntawm Kev Kho Mob Hauv Cov Mob Ntshav Qab Zib // Ntshav Qab Zib Kho - 2009. - Vol. 32 (Cov Khoom Xa Khoom 1). - P. 13–61.

Otto Natalya Yuryevna - Lub taub hau ntawm Endocrinology Department ntawm Lub Tsev Haujlwm Menyuam Menyuam Hauv Cheeb Tsam muaj npe tom qab N. N. Silishcheva ”, e-mail: [email protected]

PECULIARITIES NTAWM KEV HLOOV THIAB KEV LAG LUAM NTAWM OXIDATIVE NYOB ZE HAUV LUB ACTIVE theem NTAWM PYELONEPHRITIS HAUV COV MENYUAM

Smolensk Lub Xeev Kev Kawm Kho Mob

Cov ntaub ntawv tshawb fawb txog cov txheej txheem prooxidant thiab cov tshuaj tiv thaiv kab mob hauv 79 tus menyuam tau nthuav tawm, ntawm 49 cov menyuam yaus muaj tus kabmob pyelonephritis thiab 30 tus menyuam muaj hnub nyoog 1 txog 17 xyoos. Peculiarities ntawm kev txhim kho thiab chav kawm ntawm kev nyuaj siab oxidative hauv pyelonephritis nyob ntawm nws cov chav kawm tau qhia.

Cov lus tseem ceeb: pyelonephritis, menyuam yaus, oxidative kev nyuaj siab, ua pa oxygen hom, tiv thaiv antioxidant, chemiluminescence.

PECULIARITIES NTAWM KEV HLOOV THIAB KEV TIV THAIV OXIDATIVE NYOB ZE RAU ​​HAUV KEV UA PHEM NTAWM PYELONEPHRITIS HAUV COV MENYUAM

Tsab xov xwm nthuav tawm cov ntaub ntawv ntawm kev kawm txog prooxidant thiab cov kab mob antioxidant hauv 79 cov menyuam, suav nrog 49 cov menyuam yaus uas muaj kev ua si ntawm pyelonephritis, thiab 30 tus menyuam muaj hnub nyoog muaj hnub nyoog txog 1 txog 17. Cov yam ntxwv ntawm oxidative kev nyuab siab hauv pyelonephritis, nyob ntawm nws chav kawm, yog txiav txim siab.

Cov ntsiab lus tseem ceeb: pyelonephritis, menyuam yaus, oxidative kev nyuab siab, ua pa oxygen hom, tiv thaiv antioxidant, chemiluminescence.

Hauv cov qauv ntawm cov kev tshawb fawb pathology, tso zis tawm yog lonephritis. Cov txheej txheem dawb dhau mus koom nrog ib ntawm cov txiaj ntsig kev mob ntawm cov kab mob hauv lub nruab nrog cev hauv cov menyuam yaus.

Yam 1 ntshav qab zib mellitus: cov cim, kev noj haus thiab kev tiv thaiv tus mob ntshav qab zib hom I

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Tsuas yog ob peb lub xyoos dhau los, cov ntshav qab zib tau pom tias yog kab mob ntsig txog hnub nyoog - thaum muaj hnub nyoog yau, qee leej raug mob los ntawm nws. Hmoov tsis zoo, tsis ntev los no nws tau muaj kev nyiam ua kom muaj ntshav qab zib thaum muaj hnub nyoog yau. Cov laj thawj rau kev loj hlob ntawm tus kab mob hauv cov neeg laus thiab cov tub ntxhais hluas sib txawv: yog tias nrog lub hnub nyoog no ua rau kom cov kab mob ntawm lub cev tsis muaj zog, suav nrog rau tus txiav, thaum nyob hauv lub cev hluas no yog vim muaj cov tshuaj insulin. Sij hawm dhau los, hom kab mob ntshav qab zib no hu ua "insulin-dependant diabetes mellitus." Tam sim no nws tau ua ntau dua - hom ntshav qab zib 1. Nws yog cov kab mob metabolic tsiag ntawv los ntawm hyperglycemia.

Cov Ntsiab Lus Cov Ntsiab Lus: hyperglycemia yog cov tsos mob soj ntsuam qhia txog cov ntsiab lus ntawm cov piam thaj hauv qab zib hauv cov ntshav ntshav.

Qhov tseem ceeb sib txawv ntawm tus mob ntshav qab zib hom 1 thiab ntshav qab zib hom 2 yog tias nyob hauv rooj plaub thib ob, lub cev tuaj yeem tsim cov tshuaj insulin ywj pheej thiab, raws li, maj mam txo cov ntshav qab zib. Hauv thawj hom kab mob, insulin tsis tsim nws tus kheej thiab tus neeg mob ncaj qha nyob ntawm kev noj tshuaj muaj suab thaj thiab kev txhaj tshuaj insulin.

Hom 1 mob ntshav qab zib mellitus feem ntau pib nrog xws li mob hnyav ntawm tus kab mob uas tus neeg mob muaj peev xwm txawm tias lub npe hnub thaum thawj cov tsos mob ntawm hyperglycemia tshwm sim:

• Lub qhov ncauj qhuav
• Tubneeb
• Kev ceev ceev tso zis.

Kev poob phaus ntse, qee zaus ncav cuag 10-15 kg hauv ib hlis, kuj yog ib qho ntawm cov tsos mob ntawm tus mob ntshav qab zib hom 1.

Txhawm rau kom paub tseeb tias kev kuaj mob, kev tshawb xyuas biochemical ntawm cov ntshav thiab zis yog raug xaj. Yog tias kev kuaj pom tias muaj cov ntshav qab zib ntau ntau, thiab cov acetone thiab qabzib muaj nyob rau hauv cov zis, kev kuaj mob tau lees paub.

Ntshav Qab Zib Hom 1 yog ib tus kabmob autoimmune, thiab feem ntau ua ke nrog cov kabmob zoo sib xws - diffuse toxic goiter (Graves disease), autoimmune thyroiditis.

Chav kawm ntawm tus kab mob

Txawm hais tias thaum pib mob hnyav los, cov ntshav qab zib hom mob ntshav qab zib yuav txhim kho qeeb. Lub caij ua latent, latent qee zaum kav ntev ntau xyoo. Thiab tsuas yog thaum muaj kev puas tsuaj ntawm β-hlwb nce mus txog 80% ua cov tsos mob hauv tsev kho mob tau pib tshwm sim.

Cov lus txhais cov ntsiab lus: β - hlwb - ib hom ntawm cov hlwb ntawm endocrine txiav. Beta cell tsim cov tshuaj hormone insulin, uas ua rau cov ntshav nyob hauv qis.

Hauv kev txhim kho ntawm cov ntshav qab zib hom 1, rau qib ua qhov txawv:

1. Theem ntawm kev tshuaj ntsuam genetic predisposition. Nws yuav tsum raug sau tseg tias tsuas yog 2-5% ntawm cov tib neeg uas muaj kev mob caj ces rau hom ntshav qab zib hom 1 thiaj li kis tau. Yuav kom tau txais cov ntaub ntawv muaj txiaj ntsig ntawm cov kab mob sib kis, nws yog ib qho tsim nyog yuav tsum ua qhov kev tshawb fawb ntawm cov cim caj ces ntawm tus kab mob. Qhov muaj ntawm HLA antigens qhia tau tias qhov kev pheej hmoo ntawm kev tsim kab mob ntshav qab zib insulin yog qhov ntau. Hauv ntshav dej, lub cim no tshwm 5-10 xyoo ua ntej thawj qhov kev saib xyuas mob ntawm tus kab mob.
2. Pib ntawm txheej txheem autoimmune. Cov xwm txheej sab nraud uas tuaj yeem ua rau qhov pib ntawm tus kabmob tuaj yeem yog - cov kab mob kis (mob pob qa txha, mob qoob, mob cytomegalovirus), tshuaj, kev ntxhov siab, khoom noj khoom haus - kev siv cov kua mis sib xyaw nrog tsiaj cov tsiaj kom muaj pes tsawg leeg, muaj cov khoom uas muaj nitrosamines. Hauv 60% ntawm tus neeg mob, nws yog lwm yam sab nraud uas dhau los ua khawm pib rau kev txhim kho mob ntshav qab zib hom 1. Pancreatic insulin secretion tseem tsis tau tshwm sim nyob rau theem no, tab sis kev sim tshuaj tiv thaiv kab mob twb txiav txim siab lub xub ntiag ntawm cov tshuaj tiv thaiv.
3. Kev tsim kho ntawm kev tiv thaiv kab mob. Nws qee zaum hu ua insulin mob ntev.Nyob rau theem no, tseem tsis muaj cov kev hloov pauv hauv metabolic, tab sis kev ua kom maj mam ua kom muaj kev puas tsuaj ntawm cov hlwb betta pib tshwm sim. Hauv cov ntshav muaj qee yam kev tiv thaiv tiv thaiv kab mob rau ntau cov qauv ntawm β-hlwb - cov tshuaj tiv thaiv tiv thaiv kab mob rau insulin. Cov theem tsis muaj cov yam ntxwv tshwm sim. Hauv kev kuaj mob (feem ntau yog tso ntshav kuaj ntshav qab zib), qhov poob ntawm thawj theem ntawm insulin secretion tau pom.
4. Cov mob tiv thaiv tsis haum - ntshav qab zib mellitus. Txawm hais tias kev tso ntshav qabzib tsis muaj teebmeem, tseem tseem tsis pom txog cov tsos mob ntshav qab zib. Qhov ntsuas cov ntshav qabzib hauv qhov ncauj qhia txog kev nce nrawm ntawm cov piam thaj, uas tshwm sim los ntawm kev rhuav tshem yuav luag ib nrab ntawm cov β-hlwb. Feem ntau cov neeg mob nyob rau theem no yws yws ntawm malaise, rov muaj dua furunculosis, conjunctivitis.
5. Tag nrho ntshav qab zib mellitus ntawm thawj hom mob nrog cov tso pa tawm ntawm cov kua dej. Nyob rau theem no, tag nrho cov kev kuaj mob ntawm tus kab mob no tau pom muaj puv siab. Tus kab mob no muaj mob hnyav - tsis muaj kev kho kom zoo, tom qab 2 lub lis piam muaj kev tuag tshwm sim - ketoacidosis uas mob ntshav qab zib. Kev puas tsuaj ntawm β-hlwb nce mus txog 80-90%, txawm li cas los xij, cov roj ntsha tseem tshuav ntawm cov kua dej tseem tseem khaws cia. Yog tias cov tshuaj insulin tsis tu ncua tau pib, hauv qee cov neeg mob pib lub sijhawm ua haujlwm ruaj khov ntawm tus kab mob - "honeymoon", uas yog tus cwj pwm los ntawm qhov xav tau tsawg kawg nkaus rau insulin exogenous.
6. Ntshav qab zib mellitus uas tsis muaj qhov tsis txaus insulin - tag nrho cov ntshav qab zib. Kev puas tsuaj rau β-hlwb tau nce mus txog ib qib tseem ceeb, kev ua haujlwm ntawm cov kua dej hauv lub cev tau nres los ntawm lub cev. Cov metabolism hauv ib txwm tsis muaj peev xwm ua tau yog tias tsis muaj cov tshuaj insulin tsis tu ncua.

Tsis yog nyob rau hauv txhua tus mob ntawm hom 1 mob ntshav qab zib mellitus, xws li txoj kev txhim kho staged ntawm tus kab mob.

Kev kho mob ntshav qab zib insulin-tiv thaiv mob ntshav qab zib mellitus

Kev kho mob ntshav qab zib hom 1 yog kev noj haus nruj tshaj plaws thiab kev txhaj tshuaj insulin li niaj zaus lossis noj tshuaj muaj suab thaj. Hmoov tsis zoo, ntshav qab zib tsis yog ib qho kho tau. Lub hom phiaj ntawm txoj kev kho yog tswj kom lub cev ua haujlwm li qub thiab tiv thaiv qhov tshwm sim ntawm cov teeb meem.

Yog tias cov koob tshuaj ntawm cov tshuaj insulin raug muab xam yog lawm, tsis muaj qhov sib txawv tshwj xeeb los ntawm cov ntawv qhia zaub mov ntawm ib tus neeg ib txwm. Ib qho tseem ceeb sib txawv yog qhov yuav tsum tau los laij cov zaub mov zom zom kom tau cov zaub mov uas tau yooj yim. Qhov no tso cai rau koj los laij cov tshuaj insulin kom tsawg li sai tau.

• Cov khoom noj yuav tsum muaj ntau yam sib txawv.
• Noj zaub mov zoo - tsawg kawg 4 zaug hauv ib hnub, hauv qee qhov me me,
• Qhov nruab nrab ntim rau ib pluag mov yog 500-600 calories, yog tias muaj qhov xav kom txo qhov hnyav, ces txawm tsawg dua
• Tus nqi ntawm cov carbohydrates tuaj yeem nce ntxiv thaum tawm dag zog lub cev - ncig mus rau tebchaws, kev qhia,
• Nws yog qhov tsim nyog los muab kev nyiam rau cov tais diav. Rog, kib, ntsim, haus - tsuas yog hauv qee yam tsis muaj peev xwm.

Tseem Ceeb! Tsis txhob hla cov pluas noj qab zib nrog ntshav qab zib hauv qee kis. Zoo li overeating.

Kev saib xyuas tshwj xeeb yuav tsum tau them rau cov khoom lag luam nrog cov khoom qab zib - qee qhov lawv tsuas muaj calories tsawg dua li qab zib. Cov khoom qab zib tsawg muaj xws li aspartame, saccharide, stevioside, cyclamate. Fructose, xylitol thiab sorbitol muaj calories ntau. Tsis txhob hnov ​​qab tias cov khoom qab zib tau raug coj los suav thaum suav cov tshuaj insulin, ntxiv rau txhua yam tsis yooj yim, qhov kev puas tsuaj thiab cov txiaj ntsig ntawm fructose yuav luag zoo li qub!

Nws yog qhov nyuaj tshwj xeeb tshaj yog kev noj haus rau cov menyuam yaus uas muaj mob thiab cov hluas. Ntawm niam txiv, kev tshuaj xyuas tas li yog qhov tsim nyog kom tus menyuam tsis txhob noj cov zaub mov uas raug txwv thiab tsis ua rau muaj kev cuam tshuam loj.

Cov khoom lag luam uas raug txwv tsis pub muaj ntshav qab zib mellitus ntawm thawj hom: chocolate, biscuits, qab zib, jam, khoom qab zib thiab lwm yam, muaj cov kuab ntawm cov zom zaub mov ntau. Ntawm cov txiv hmab txiv ntoo - txiv quav ntswv nyoos.

Qhov koob tshuaj insulin yuav tsum tau suav rau txhua tus noj mov thiab txhua hnub, txawm tias nag hmo ntawv qhia zaub mov tsis txawv ntau ntawm hnub no. Qhov no feem ntau yog vim qhov tseeb tias qhov xav tau cov tshuaj insulin tuaj yeem hloov pauv thaum nruab hnub.

Saib xyuas! Cawv!

Cov cawv me me rau cov ntshav qab zib hom 1 tsis raug txwv. Qhov phom sij ntawm kev haus dej cawv yog cov hauv qab no - thaum qaug cawv, ib tug neeg tsis tuaj yeem tswj hwm nws tus mob thiab tsis nco ntsoov pom cov xwm txheej phom sij ntawm kev nce siab hauv cov ntshav qab zib hauv lub sijhawm thiab tsis muaj sijhawm los txhaj tshuaj insulin.

Tsis tas li ntawd, lub xeev hypoglycemic thiab nws cov paib ua ke nrog lub cim ntawm intoxication - hais lus tsis meej, tsis sib haum ntawm kev txav. Thiab yog tias tus mob no tau pib nyob hauv zej tsoom sawv daws, tsis hnov ​​tsw haus cawv tsis pub lwm tus los ntsuas qhov txaus ntshai rau tib neeg lub neej kom raws sijhawm. Raws li qhov, lub sijhawm tsim nyog los cawm lub neej yog tu.

Lub cev qoj ib ce

Cov kev tawm dag zog lub cev yog qhov tsis tuaj yeem ua lub neej nyob ntawm ib tus neeg. Hauv cov ntshav qab zib mellitus, kev tawm dag zog tsis yog sib kis, tab sis muaj qee txoj cai ua kom lawv muaj txiaj ntsig zoo rau lub cev.

1. Thawj txoj cai. Kev qoj ib ce tuaj yeem nqa tawm tsuas yog tiv thaiv keeb kwm ntawm kev them nyiaj ntev ntev rau ntshav qab zib. Hauv theem ntawm cov ntshav qab zib ntau dua 15 mmol / l, kev qoj ib ce yog contraindicated.
2. Txoj cai thib ob. Nrog kev siv dag zog - kev kawm lub cev, ua luam dej, txawm tias ib qho disco - koj yuav tsum noj 1 X.E. txhua ib nrab teev. ntxiv rau. Nws tuaj yeem yog cov khob cij, kua txiv.
3. Txoj cai thib peb. Yog tias kev qoj ib ce ntev ntev, nws yog ib qho tsim nyog yuav tau txo cov koob tshuaj insulin los ntawm 20-50%. Yog tias lub qog ntshav qab zib tseem ua rau nws tus kheej tau hnov, tom qab ntawv nws yuav zoo dua los them rau nws los ntawm kev noj cov zaub mov uas muaj zaub mov tau yooj yim - kua txiv, dej qab zib
4. Txoj Cai Plaub Kev tawm dag zog kom tau zoo tshaj yog ob peb teev tom qab noj mov tseem ceeb. Nyob rau lub sijhawm no, qhov ntxim nyiam ntawm kev txhim kho hypoglycemia yog tsawg.
5. Txoj cai thib tsib. Kev tawm dag zog lub cev yuav tsum xav txog tus neeg tus yam ntxwv ntawm tus neeg mob - lub hnub nyoog, kev tawm dag zog, kev noj qab haus huv txhua yam.

Nco ntsoov tias haus dej haus txaus, vim hais tias thaum lub sijhawm ua haujlwm poob cov kua dej hauv lub cev nce ntxiv. Koj yuav tsum ua kom tiav cov chav kawm los ntawm kev txo qhov kev tawm dag zog ntawm kev tawm dag zog, txav mus rau lwm tus so. Qhov no yuav tso cai rau lub cev kom maj mam txias thiab nkag mus rau qhov kev ua haujlwm zoo rau kev so.

Turmeric rau hom 1 thiab hom 2 ntshav qab zib

• Hais txog cov txiaj ntsig ntawm turmeric
• Hais txog kev siv
• Hais txog cov zaub mov txawv

Mob ntshav qab zib mellitus xav tau kev kho mob nquag, uas koom nrog kev siv tsis tsuas cov tshuaj pom zoo los ntawm tus kws tshaj lij, tab sis kuj siv qee qhov kev siv tshuaj kho mob ib txwm muaj. Cov kev kho mob zoo li no yuav tsum tau txiav txim siab ua tiav rau hom 1 thiab ntshav qab zib hom 2, pab ua kom tsis txhob poob siab insulin. Hauv qhov no, nws yuav tsum raug sau tseg tias cov txuj lom xws li turmeric ua si lub luag haujlwm tshwj xeeb hauv kev rov qab kho ntshav qab zib. Hais txog nws cov khoom muaj txiaj ntsig, nuances ntawm kev thov thiab ntau yam ntxiv tom qab hauv cov ntawv nyeem.

Hais txog cov txiaj ntsig ntawm turmeric

Qhov tseeb, nws muaj peev xwm teev txhua qhov laj thawj ntawm kev noj tshuaj turmeric ntev heev, vim tias nws yog kab lis kev cai tiag tiag uas yuav muaj txiaj ntsig zoo rau txhua yam ntshav qab zib mellitus thiab yuav tsis ua rau muaj cov insulin ntau ntxiv. Nws yog tsim nyog nqa tawm kev kho mob nrog nws, vim hais tias nws:

• normalizes ntshav siab,
• txo qhov feem ntawm cov roj (cholesterol) phem thiab ua rau nws muaj peev xwm tiv thaiv atherosclerosis,
• siv txoj kev tiv thaiv zoo,
• tsim kev tiv thaiv mob khaub thuas, kho tau lawv - insulin koob txhaj tshuaj kuj tuaj yeem siv rau kev kho,
• muab kev ua haujlwm ntau dua ntawm lub plawv kev mob.

Tsis tas li ntawd, turmeric yog ib qho tshuaj tua kab mob zoo tshaj plaws ntawm lub hauv paus chiv keeb. Nws tsis muaj txoj hauv kev tuaj yeem ua mob rau lub plab hnyuv microflora. Tsis tas li ntawd, noj cov txuj lom no kuj yog vim qhov tseeb tias nws muaj cov yam ntxwv los tiv thaiv thiab muaj peev xwm txo qis tsis tsuas yog xav noj cov khoom noj muaj roj, tab sis kuj kho cov txim ntawm cov txheej txheem no, kom ntseeg tau tias kev khaws cov tshuaj insulin. Txhua yam no, muaj tseeb, nws muaj txiaj ntsig zoo rau ntshav qab zib, ob hom thawj thiab hom thib ob.

Cov kws tshaj lij kuj tseem ceeb txog qhov txo qis hauv cov lus piv ntawm cov piam thaj hauv cov ntshav thiab txo qis ntawm cov qog adipose, uas, tau kawg, cuam tshuam tsis zoo rau kev noj qab haus huv ntawm cov ntshav qab zib. Tias yog vim li cas nws yuav tsum tau muab pov tseg, zoo li muaj teeb meem nrog lub cev uas tsim cov tshuaj insulin. Tsis tas li ntawd, kho cov kab mob turmeric nrog ntshav qab zib tshem tawm los yog tsis tso cai rau kev txhim kho ntawm kev muaj teeb meem hauv qhov mob ntshav qab zib mellitus. Hauv tshwj xeeb, qhov no siv tsis tas rau atherosclerosis, tab sis kuj rau mob caj dab.

Cov npe ntawm cov cheebtsam ntawm turmeric suav nrog cov vitamins uas koom rau pawg B, C, E thiab K, nrog rau cov kab kawm, cov tshuaj tiv thaiv ntuj thiab cov roj tseem ceeb, nrog rau curcumin. Vim li ntawd cov lus piav qhia yuav tsum coj los ntawm txhua tus neeg mob ntshav qab zib.

Xws li cov nplua nuj muaj pes tsawg leeg cuam tshuam txhua yam kev zom zaub mov uas tshwm sim hauv tib neeg lub cev, yog li nws raug nquahu kom siv nws txhua hnub. Cov kev kho mob zoo li no yuav tsum tau ua rau lub ntsiab ntawm:

1. kev tiv thaiv ntawm ntau ailments,
2. nce "zoo" ntawm kev tiv thaiv kab mob.

Hais txog kev siv

Hauv kev ua cov khoom siv nquag ntawm turmeric, qee qhov kev cai yuav tsum ua raws.

Muab hais tias qhov no tseem yog seasoning nrog lub suab saj, koj yuav tsum tsis txhob nqa nrog nws siv.

Tib lub sijhawm, thaum mob ntshav qab zib mellitus ntawm ib yam twg nrog cov teeb meem ntawm txoj hnyuv, nws raug nquahu kom siv cov turmeric tsuas yog tom qab sab laj nrog tus kws tshaj lij.

Kev kho mob nrog curcumin qhib lub sijhawm los txo qis ntawm cov roj cholesterol hauv cov ntshav thiab ua kom cov ntshav muaj pes tsawg leeg. Nyob rau tib lub sijhawm, nws tsis yog tsuas yog ua kom huv, tab sis kuj tseem ua rau cov qe ntshav liab kom zoo dua tuaj, thiab cov neeg ua haujlwm ntawm cov platelets tseem txo qis. Hauv qhov no, noj cov txuj lom no yuav tsum ua tib zoo thiab cov neeg muaj ntshav.

Kev muab nws lub peev xwm tshem tawm cov tshuaj phem thiab co toxins ntawm lub cev, nws raug qhia kom ntxiv rau cov zaub mov nrog kev siv tshuaj ntev los yog kev kho mob ntshav qab zib. Tsis tas li, txoj kev kho yuav cuam tshuam rau kev lom nrog ntau yam tshuaj tua kab thiab tshuaj lom neeg.

Ua tsaug rau txhua yam ntawm nws txoj kev kho kom zoo, turmeric rau cov ntshav qab zib ntawm txhua yam:

• tsis tsuas yog txo cov ntshav qabzib hauv cov ntshav,
• tab sis kuj tseem ua kom nrawm dua kev rov qab ntawm lub cev.

Ntxiv rau, kev siv lub sijhawm piav qhia cov txuj lom ua rau nws tuaj yeem zam qhov pib ntawm ntshav qab zib mellitus rau cov uas muaj kev pheej hmoo. Yog vim li ntawd turmeric hauv ntshav qab zib yuav tsum yog qhov tseem ceeb ntawm kev noj haus. Cov zaub mov dab tsi nrog nws siv?

Hais txog cov zaub mov txawv

Rau txhua hom ntshav qab zib, cov zaub mov txawv ntawm turmeric tseem zoo li qub. Piv txwv li, koj tuaj yeem ua cov tshuaj yej muaj txiaj ntsig zoo, uas suav nrog cov khoom xyaw hauv qab no: peb peb diav tshuaj yej dub, ib me nyuam diav me me ntawm cinnamon, ob diav ntawm turmeric thiab peb me me ntawm qhiav.

Tsis tas li, kefir, zib ntab thiab mis nyuj rau saj yuav tsum muaj nyob hauv cov tshuaj yej no - txhua qhov feem cuam yuav tsum muaj ntshav qab zib.

Kev ua noj ua haus siv qhov chaw raws li cov txheej txheem hauv qab no: turmeric yog nchuav nrog cov dej npau npau, nrog rau cov tshuaj yej dub, cinnamon, qhiav thiab zib ntab. Tag nrho cov no tau muab sib xyaw, txias thiab kefir ntxiv. Nws raug tso cai siv tshuaj yej thaum sawv ntxov lossis yav tsaus ntuj, ib khob ib. Koj tseem tuaj yeem npaj cov paj npleg nqaij nrog turmeric, uas yog qhov zoo rau cov neeg mob ntshav qab zib.

Tws dos thiab nqaij (nyiam dua nqaij nyuj) nrog nqaij grinder lossis blender. Tag nrho cov no yog muab tso rau hauv lub lauj kaub nrog zaub roj thiab kib rau txog kaum feeb. Tom ntej:

1. txias nqaij nrog dos yog sib xyaw nrog tus so hauv cov khoom xyaw (qe, tshuaj ntsuab, turmeric, qaub cream thiab butter),
2. nteg tawm hauv cov tais ci tshwj xeeb.

Ib lub tais yog npaj rau ntawm qhov kub tsawg kawg 180 degrees rau 50 feeb. Nws yuav pab tau zoo rau cov ntshav qab zib thiab yuav muab ib txoj hauv kev tsis yog rau saturate lub cev, tab sis kuj tseem yuav txhawb nws nrog cov tshuaj muaj txiaj ntsig.

Kev kho mob rau cov menyuam yaus uas muaj ntshav qab zib hom 1 nrog kev tso tshuaj insulin Humalog: Kev paub txog Polish

Peb coj mus rau koj mloog ib tug txhais lus los ntawm lus Askiv ntawm ib tsab xov xwm los ntawm kws kho mob Polish luam tawm nyob rau lub Cuaj hlis 2012. Qhov no yog ib qho ntawm ob peb pab tau ua kom cov insulin dilution cov ntaub ntawv. Cov neeg nyeem ntawm peb lub xaib, suav nrog cov neeg laus uas tswj hwm lawv cov ntshav qab zib uas muaj zaub mov tsis zoo rau lub cev, yuav tsum txhawm rau insulin, vim hais tias tsis yog li ntawd cov koob tshuaj yuav ua rau siab dhau. Hmoov tsis zoo, cov tshuaj ua haujlwm, nrog rau cov tuam txhab tsim cov tshuaj insulin thiab cov koob txhaj tshuaj, tsis quav ntsej cov ncauj lus no. Nyeem peb cov lus nkag rau hauv qab heev, tom qab ntawv ntawm kab lus.

Rau cov menyuam yaus tsawg tshaj plaws uas muaj ntshav qab zib hom 1, koob tshuaj insulin txhua hnub feem ntau tsawg dua 5-10 ntu. Qhov no txhais tau hais tias cov neeg mob zoo li no ib hnub yuav tsum nkag tsawg dua 0.05-0.1 ml ntawm insulin ntawm qhov siab ntawm 100 PIECES / ml. Qee tus menyuam yaus tsuas xav tau 0.2-0.3 PIECES ntawm bolus (luv luv) insulin los npog 10 gram ntawm cov carbohydrates noj. Qhov no yog qhov tsis txaus ntseeg, lub koob tshuaj me me ntawm 0.002-0.003 ml ntawm cov tshuaj insulin ntawm qhov ua kom siab ntawm 100 PIECES / ml.

Vim li cas kuv thiaj yuav tsum txhav tshuaj insulin

Yog tias qis kawg ntawm cov tshuaj insulin xav tau los kho ntshav qab zib, qhov no tsim teeb meem thaum sim ua kom paub tseeb thiab ruaj khov subcutaneous tswj hwm ntawm insulin los ntawm koob txhaj tshuaj lossis insulin twj tso kua mis. Hauv cov twj tso tawm, lub tswb yog feem ntau ua rau.

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Ntshav Qab Zib 1 yog kuaj tau rau cov menyuam yaus thaum hnub nyoog yau dua. Yog li, qhov teeb meem ntawm kev tswj hwm qhov qis kawg ntawm cov tshuaj insulin cuam tshuam ntau dua thiab ntau cov neeg mob. Feem ntau, cov tshuaj insulin lyspro (Humalog), diluted nrog cov kua tshwj xeeb los ntawm tus tsim kev lag luam, yog siv rau cov tshuaj insulin kho rau cov menyuam mos. Hauv tsab xov xwm niaj hnub no, peb nthuav qhia qhov kev paub dhau los ntawm kev siv lyspro insulin (Humalog), diluted nrog saline 10 zaug - rau ib qho ntsiab lus ntawm 10 PIECES / ml, rau kev tso kua mis insulin rau hauv tus menyuam yaus.

• Hom 1 kho mob ntshav qab zib rau cov neeg laus thiab menyuam
• Yam 1 mob ntshav qab zib
• Honeymoon lub sijhawm thiab yuav ua li cas txuas ntxiv nws
• Cov txheej txheem ntawm kev siv tshuaj insulin tsis muaj mob
• Mob ntshav qab zib Hom 1 rau menyuam yaus raug kho yam tsis raug siv tshuaj noj kom yog. Xam phaj nrog tsev neeg.
• Yuav ua li cas qeeb ntawm kev ua haujlwm ntawm lub raum

Vim li cas koj thiaj li txiav txim siab sim diluting Humalog nrog kua ntsev?

Ib tug tub hluas hnub nyoog 2.5 xyoo, tau los ntawm kev mob ntshav qab zib hom 1 tau 12 lub hlis lawm, txij thaum xub thawj nws tau raug kho mob los ntawm cov tshuaj insulin kho. Ua ntej lawv siv NovoRapid insulin, tom qab ntawd hloov mus rau Humalog. Tus me nyuam tsis qab los noj mov tsis zoo, thiab nws qhov siab thiab qhov hnyav tau nyob ze rau hauv qab ntawm qhov ib txwm nyob rau nws lub hnub nyoog thiab tub los ntxhais. Glycated hemoglobin - 6.4-6.7%. Cov teeb meem technical nrog lub twj tso kua mis insulin tshwm sim ntau dhau - ntau zaus hauv ib lub lis piam. Vim li no, txhua lub sijhawm infusion teeb tuaj yeem siv tsis pub dhau 2 hnub. Kev piam sij hauv cov ntshav qab zib tau siab (9.6 ± 5.16 mmol / L), qab zib tau ntsuas 10-17 zaug hauv ib hnub. Cov koob tshuaj ntawm cov insulin yog 4.0-6.5 IU ib hnub (0.41-0.62 IU / kg lub cev qhov hnyav), uas 18-25% yog qhov tseem ceeb.

• Kev kho mob ntshav qab zib nrog insulin: pib ntawm no. Hom insulin thiab txoj cai rau nws cov khoom cia.
• Yuav siv hom tshuaj insulin dab tsi rau kev txhaj tshuaj, sijhawm lub sijhawm twg thiab siv sijhawm twg. Cov txheej txheem rau hom ntshav qab zib hom 1 thiab ntshav qab zib hom 2.
• Yuav ua li cas thiaj li txhaj tshuaj insulin tsis hnov ​​mob. Subcutaneous Qhov Kev Siv Insulin
• Cov tshuaj insulin cov koob txhaj tshuaj, koob txhaj tshuaj thiab koob rau lawv. Cov koob txhaj tshuaj twg zoo siv dua.
• Lantus thiab Levemir - ncua kev ua yeeb yam insulin. Ncuav qab zib thaum sawv ntxov nyob rau ntawm lub plab khoob
• Ultrashort insulin Humalog, NovoRapid thiab Apidra. Tib neeg luv insulin
• Muab xam los ntawm cov koob tshuaj insulin ua ntej noj mov. Yuav ua li cas kom qis qab zib rau li qub yog tias nws dhia
• Yuav ua li cas txhawm rau cov tshuaj insulin kom raug txhaj tshuaj qis
• Insulin twj tso kua mis: pros thiab cons.Tso kua mis kho

Cov teeb meem uas ua rau peb sim thim tshuaj insulin nrog kev ua ntsev yog cov hauv qab no:

• Qhov “cim npe” insulin dilution kua los ntawm lub khw tsim khoom tsis tau muaj.
• Tus neeg mob tau qhia txog kev hloov pauv zuj zus hauv theem ntawm bilirubin thiab cov kua tsib kua qaub hauv cov ntshav. Qhov no tuaj yeem txhais tau tias cov tshuaj muaj zog nyob hauv insulin thiab cov dej ua kua (metacresol thiab phenol) muaj teeb meem rau nws lub siab.

Pawg Neeg Saib Xyuas Kev Ncaj Ncees pom zoo rau kev sim siv cov tshuaj insulin uas tov nrog ntsev ua kev kho. Cov niam txiv tau kos npe rau tsab ntawv pom zoo tso cai. Lawv tau txais cov lus qhia ntxaws ntxiv yuav ua li cas txhawm rau insulin nrog saline thiab yuav ua li cas los teeb cov chaw ntawm lub tshuab nqus insulin.

Cov txiaj ntsig ntawm kev tso kua mis insulin kho nrog diluted insulin

Cov niam txiv tau pib siv cov twj tso kua mis kho nrog insulin, diluted nrog saline 10 zaug, ntawm kev kho mob sab nraud, i.e. hauv tsev, tsis muaj tshuaj xyuas tas li los ntawm cov kws tshwj xeeb. Ib qho kev daws ntawm diluted insulin Humalog tau npaj dua txhua 3 hnub. Tam sim no, siv cov roj ntsha insulin, 10 npaug ntawm cov kua dej nkag mus rau hauv tus menyuam lub cev ntau dua li cov koob tshuaj insulin lawm.

Txij thawj hnub ntawm kev kho mob ntshav qab zib raws li txoj kev cai tshiab, ntau zaus teeb meem cov teeb meem nrog ib lub twj tso kua mis tsis muaj zog txaus. Cov ntshav qab zib cov ntshav qab zib tsawg zuj zus thiab dhau los ua kom paub tseeb tseeb, nce txog 7.7 ± 3.94 mmol / L. Cov no yog cov ntsuas raws li cov txiaj ntsig ntawm kev ntsuas ntshav qab zib 13-14 zaug hauv ib hnub. Tshaj 20 lub hlis tom ntej, kev txhaws ntawm cannula ntawm lub twj tso kua mis los ntawm insulin muaju tau pom tsuas yog 3 zaug. Ib qho xwm txheej ntawm cov ntshav qog ntshav hnyav tau tshwm sim (cov ntshav qab zib yog 1.22 mmol / L), uas yuav tsum muaj kev tswj hwm ntawm glucagon. Hauv qhov xwm txheej no, tus me nyuam tsis nco qab lawm 2-3 feeb. Glycated hemoglobin hauv thawj 15 lub hlis yog 6.3-6.9%, tab sis 5 lub hlis tom ntej nws tau nce mus rau 7.3-7.5% tiv thaiv keeb kwm ntawm kev kis mob khaub thuas.

Cov koob tshuaj ntawm Humalog insulin, diluted 10 zaug, thiab tswj hwm nrog lub twj tso kua mis, yog 2.8–4.6 U / hnub (0.2-0.37 U / kg lub cev hnyav), ntawm cov uas 35-55% yog qhov yooj yim nyob ntawm seb lub cev puas tsuaj thiab muaj muaj tus kab mob sib kis. Tus me nyuam tseem tsis qab los noj mov, thiab qhov no cuam tshuam rau kev tswj hwm nws cov ntshav qab zib. Tab sis nws tab tom tsim tawm ib txwm, nce hauv qhov siab thiab qhov hnyav, txawm hais tias cov ntsuas no tseem nyob hauv qis dua ntawm kev txwv hnub nyoog. Qib ntawm bilirubin thiab bile acids nyob rau hauv cov ntshav poob qis rau qhov qub. Zaus ntawm cov teeb meem kev nrog twj tso kua mis insulin kuj poob qis. Niam txiv zoo siab. Lawv tsis kam hloov tus menyuam rov qab mus rau hauv insulin ntawm qhov siab ntawm 100 IU / ml.

Peb tau txiav txim siab tsuas yog ib rooj plaub, tab sis peb cov kev paub yuav pab tau zoo rau lwm cov kev coj ua. Peb xav tias diluting Humalog insulin 10 zaug rau kev siv nrog lub twj tso kua mis ua raws li txoj kev kho yuav pab tau hauv kev kov yeej cov teeb meem kev qhia. Txoj kev kho mob no tau ua rau muaj kev nyab xeeb rau tus menyuam yaus uas xav tau cov tshuaj insulin tsawg heev. Lub hauv paus tseem ceeb hauv kev kho kom zoo yog kev koom tes nrog niam txiv thiab ua tib zoo saib xyuas tus txheej txheem los ntawm cov kws tshwj xeeb. Cov txheej txheem insulin zom zaws tuaj yeem ua kom yooj yim thaum kaw lub voj voos insulin kev tswj hwm raug tsim kho rau cov menyuam yau tshaj. Txhawm rau kos cov lus xaus kawg, xav tau kev tshawb fawb ntxiv, nrog rau cov lus pom los ntawm cov neeg tsim tawm insulin.

Cov lus qhia rau lub xaib Ntshav qab zib-Med.Com

Rau luv luv thiab ultrashort hom insulin, qhov kev coj ua no tsis raug pom zoo los ntawm cov tuam ntxhab, tab sis nws kuj tsis txwv. Hauv kev sib tham txog ntshav qab zib, koj tuaj yeem paub tias nws muab ntau los sis tsawg dua cov txiaj ntsig zoo. Koj tuaj yeem hloov ntawm Humalog mus rau Actrapid ua ntej noj mov uas ua qeeb dua thiab du. Tab sis yog tias koj xav tswj cov ntshav qab zib hauv ib tus menyuam tiag, koj yuav tsum txhaws rau nws ib yam nkaus.

Nws tau raug pov thawj tias cov me nyuam yaus uas muaj ntshav qab zib hom 1 xav tau txhaws nrog insulin yog li lawv tuaj yeem txhaj tshuaj me me ib txwm. Thiab yog tias koj ua raws li peb txoj kev kho mob ntshav qab zib hom 2 lossis hom 1 kev kho mob ntshav qab zib, uas yog, ua raws li cov zaub mov tsis muaj carbohydrate, tom qab ntawd qhov muaj feem ntau tsis tsuas yog cov menyuam yaus tab sis tus neeg laus yuav xav tau cov tshuaj insulin. Vim tias yog tias koj qhia txog cov tshuaj tiv thaiv kab mob siab tshaj plaws, nws yuav ua rau muaj ntshav qab zib thiab nquag muaj ntshav ntau hauv lub cev.

Hmoov tsis zoo, cov tshuaj ua haujlwm tsis lees paub lub ntsiab lus ntawm insulin dilution. Txog rau hnub tim, tshaj tawm cov ntawv tshaj tawm txog kev kho mob ntshav qab zib hauv cov neeg hais lus Lavxias yog 2011 ob lub ntim tsim los ntawm I. I. Dedov thiab M. V. Shestakova.

Qhov no yog xim xim luam tawm, ze li 1,400 nplooj ntawv. Alas, nws tsis hais ib lo lus hais txog yuav txo cov tshuaj insulin li cas, txawm nyob hauv seem ntawm kev kho mob ntshav qab zib hom 1 hauv cov menyuam yau tshaj. Tsis yog hais cov laus. Cov kws sau ntawv kuj tseem tsis quav ntsej txog kev noj zaub mov kom muaj cov zaub mov uas muaj txiaj ntsig rau lub cev, txawm hais tias qhov no ua tau zoo tshaj plaws los tswj ntshav qab zib thiab tiv thaiv kom tsis txhob muaj ntshav qab zib. Nov yog kev vwm.

Hauv kev ncaj ncees, peb nco ntsoov tias tib lub txiaj ntsig kev npau taws yog tshwm sim txawv teb chaws. Cov ntawv tshiab hais ua lus Askiv thiab phau ntawv qhia txog kev kho mob ntshav qab zib kuj tsis hais txog kev noj zaub mov kom tsis rog lossis noj tshuaj ntxaib. Kuv tsuas yog yuav txhawb koj kom kawm peb cov ntawv tseem ceeb, "Yuav ua li cas Dilute Insulin rau Qhov Ntsuas Tshaj Tawm Qis Qis." Siv cov hau kev uas twb tau ua pov thawj hauv kev coj ua, thiab sim koj tus kheej.

Hauv xyoo 1970, cov tshuaj raug cai tau tawm tsam qhov tshwm sim ntawm cov ntshav qab zib hauv tsev rau tsawg kawg 5 xyoos, uas yuav ua rau cov neeg mob ntshav qab zib los ntsuas nws cov ntshav qab zib. Txhua lub xyoo, cov kws kho mob tau hais tias muaj ntshav qab zib, tswj ntshav qab zib kom zoo li ib txwm muaj hauv cov neeg noj qab haus huv yog qhov tsis muaj txiaj ntsig thiab txaus ntshai. Nyeem qhov Biography ntawm Dr. Bernstein kom ntxaws ntxiv. Cov hnub no, keeb kwm rov ua nws tus kheej nrog kev noj zaub mov kom tsawg los tswj hom 1 thiab ntshav qab zib hom 2.

Nyeem vim li cas peb tsis pom zoo siv lub tshuab nqus ntshav, txawm tias cov menyuam yaus muaj ntshav qab zib hom 1. Coj koj tus menyuam noj cov zaub mov noj kom tsawg thaum uas yuav pub mis niam dhau. Hloov cov tshuaj insulin koob txhaj nrog lub twj tso kua mis yuav tsum tau pom zoo tsuas yog thaum cov twj kawm paub ntsuas cov ntshav qab zib thiab kho cov tshuaj insulin raws li cov txiaj ntsig ntawm cov kev ntsuas no. Hauv tsab xov xwm, cov kab laum insulin siab tshaj plaws ntawm lub neej yav tom ntej hu ua "kev kaw lub voj voog." Thiab tseem, qee qhov teeb meem daws tsis tau uas lawv ua yuav tsis ploj.

Koj yuav pab tau lub zej zog loj-hais lus Lavxias ntawm cov neeg mob ntshav qab zib yog tias koj qhia cov kev tshwm sim ntawm koj cov kev sim ntawm insulin dilution hauv cov lus rau cov lus.

Tus Kws Kho Mob Tawm Tswv Yim

Tom qab tso tawm, cov niam txiv tau hloov lub rooj noj mov 9 daim ntawv pom zoo nrog kev noj zaub mov kom tsawg ntawm 6-8 XE, tshem tawm cov nplais nplej, mov ci, cov txiv ntoo qab zib, qab zib, txhua yam dej qab zib nrog qab zib. Txuas ntxiv rau kev haus dej cawv thiab kev tawm dag zog lub cev.

Txij li hnub tim 04/07/2016, txhawm rau tsim kev tiv thaiv kab mob, Phoenix Fohow cell khoom noj khoom haus (monosaccharides, disaccharides, cordyceps-uas muaj cov khoom siv roj ntsha) tau siv raws li txoj cai, kev ua kom huv, thiab cov khoom noj khoom haus zoo.

Maj mam, thaum glycemia poob zuj zus, cov koob tshuaj ntawm cov tshuaj insulin txo qis dua. Tom qab 2 lub hlis, tus neeg mob muaj peev xwm tshem tawm txoj kev siv tshuaj insulin tag nrhoCov. Los ntawm leej niam tsab ntawv: “Lub Rau Hli 10 peb ua tiav tsis kam cov tshuaj insulin, thaum lub suab thaj tseem nyob ruaj khov: los ntawm 4.8 txog 7 mmol / l, nce mus txog qhov siab ntawm 8.5-9 mmol / l tom qab noj. "

09/10/2016 3 lub hlis tom qab tshem tawm cov tshuaj insulin: glycated hemoglobin 6 %C peptide 0.53 ng / ml, nrog ib tus qauv ntawm 0.79 - 4.19. Qhia tau taw qhia kom rov qab tsim kho lawv tus kheej cov insulin.

Rov qab nco niam menyuam

08.10.2016
Thaum kawg, Kuv sau rau koj txog qhov tshwm sim.
Cov tub ntxhais hluas muaj hnub nyoog 14 xyoos, qhov tshwm sim ntawm cov ntshav qab zib hom 1 rau lub Ob Hlis 27, 2016, Glycated hemoglobin 13.8, kev tshuaj xyuas kab mob tau zoo txhua yam (kev paub tseeb ntawm hom 1 ntshav qab zib). Kev siv tshuaj insulin raug sau tseg: 10 lub roj pleev qhov muag (1 lub sijhawm ib hnub) thiab 6-7 units ntawm apidra rau ib pluag noj (3 zaug hauv ib hnub). Kev tawm hauv tsev kho mob thaum Lub Peb Hlis 3 nrog cov ntshav qabzib hauv cov ntshav 6 mus txog 12 units.

Tam sim ntawd tom qab tso tawm, txoj kev noj haus tau hloov: 6-8 XE ib hnub hloov qhov kev pom zoo 18-20 XE rau ib hnub, zaub mov, mov ci, txiv hmab txiv ntoo qab zib, qab zib, tag nrho cov dej qab zib rau cov qab zib tau muab cais tawm. Hauv tag nrho, lub hauv paus ntawm kev noj haus yog: nqaij, ntses, zaub, nqaij nruab deg, tsev cheese, kua mis nyeem qaub, txiv ntoo thiab noob.

Lub Plaub Hlis 7, raws li kev pom zoo ntawm Dr. Tetyuk, kev tswj hwm ntawm Fohow npaj tau pib. Nyob rau tib lub sijhawm, lawv tau kawm ib chav koom nrog thiab qhia txog kev ua noj kom zoo thiab kev ua kis las.

Cov koob tshuaj insulin tau txo qis tas li, uas feem ntau yuav yog vim cov kev sib xyaw ua ke thiab "honeymoon", uas qee zaum tshwm sim tom qab ua kom muaj ntshav qab zib.

Thaum Lub Tsib Hlis 25, 2016, glycated hemoglobin yog nyob rau theem ntawm 6.8. Cov piam thaj hauv qab tau ruaj khov yam tsis muaj hyper- thiab hypoglycemia.

Lub Rau Hli 10, peb tso tawm cov tshuaj insulin pov tseg tag nrho, thaum cov piam thaj tseem ruaj khov nyob rau ntawm thaj tsam ntawm 4.8 txog 7, mus txog qhov siab kawg ntawm 8,5-9 units tom qab noj mov. Kev nqus ntawm Fohow tshuaj thiab ua raws li kev noj haus tseem tsis tau hloov pauv.

Nyob rau lub caij ntuj sov, cov txiv ntoo thiab zaub txhua lub caij tau muab los qhia ntxiv (nws nyuaj rau tawm tsam, txij li ob tus menyuam noj txhua). Muaj txiv duaj, thiab dib liab, thiab txhua hom txiv ntoo. Qos yaj ywm xyaum tsis nce suab thaj (tshwj xeeb yog txias hauv cov zaub xam lav), tab sis peb tsis noj cov qos yaj ywm hauv txoj ntsiab cai.

Tag nrho cov txiaj ntsig rau lub Cuaj Hli 10: glycated hemoglobin 6 units, c-peptide 0.53 units, nrog tus cai ntawm 0.79 - 4.19. Txais tos ntawm Fohow cov khoom lag luam tau dhau los ua tsis yog rau tus hluas piav qhia saum toj no, tab sis kuj tseem rau peb ob tug me nyuam ntxiv thiab.

Hloov kho 10.09.2016 3 lub hlis tom qab tshem tawm ntawm exulinous insulin: glycated hemoglobin 6,0 % ntawm ib txwm (2.0 - 6.0), C-peptide 0.53 ng / ml ntawm qhov nruab nrab (0.79 - 4.19).

12/17/2016 Cov Khoom Kho Dua Tshiab 6 lub hlis tom qab tsis ua tiav ntawm cov tshuaj insulin: glycated hemoglobin 5,6 % (2.0 - 6.0), C-peptide 0.88 ng / ml (0,79 – 4,19). Ob qhov ntsuas yog qhov qub, qhia tau tias ua tiav ntawm kev ua tiav pancreaticCov. Txoj haujlwm yog kom ncaj ncaj rau nthuav cov zaub mov noj thaum ua kom tshwm sim.

Pathogenesis ntawm hom 1 mob ntshav qab zib

1. Noob kev tshawb xav - 2 hloov khoom rau ntawm 6 lub chromosome. Lawv cuam tshuam nrog HLA-system, uas txiav txim xyuas cov lus teb ntawm lub cev thiab beta hlwb mus rau ntau cov ntshav siab.
2. Tus kab mob viral (cov kab mob kis rau cov neeg mob ntshav qab zib ua rau muaj kev puas tsuaj rau cov qe ntshav lossis ua rau muaj tus kabmob txuas ntxiv nrog rau kev txhim kho autoimmune fab hauv islet nqaij.)

Lub hauv paus yog qhov tsis txaus insulin.

Qhov tsis muaj peev xwm ntawm cov kua nplaum nkag mus rau insulin-cov ntaub so ntswg ua rau lub zog tsis txaus, ua rau cov lipolysis sib zog thiab tiv thaiv tsis txaus, uas cuam tshuam nrog kev poob phaus. Nyob rau hauv cov xwm txheej ntawm insulin deficiency thiab lub zog tsis txaus, kev tsim cov tshuaj hormones contrainsular yog txwv tsis pub, uas, txawm hais tias nce glycemia, ua rau kev ua kom muaj zog ntawm GNG. Kev lipolysis ntau nyob rau hauv cov nqaij adipose ua rau muaj kev nce ntau ntxiv nyob rau hauv kev ua siab ntev ntawm FAs. Nrog cov tshuaj insulin tsis txaus, lub siab liposenthetic muaj peev xwm ua rau lub siab raug tshem tawm, thiab FAs dawb pib koom tes hauv ketogenesis. Kev sib txuam ntawm ketone lub cev ua rau kev loj hlob ntawm cov kab mob ntshav qab zib ketosis, thiab yav tom ntej - ketoacidosis. Nrog rau kev nce ntxiv hauv lub cev qhuav dej thiab acidosis, lub cev tsis nco qab tshwm sim, uas tsis tas yuav muaj tshuaj tua kab mob insulin thiab lub cev ua kom lub cev tsis nco qab txog qhov tuag.

✧ kev ua yeeb yam ntev - Lantus (pib ntawm kev ua tom qab 4 teev, sijhawm ua haujlwm - txog 28 teev).

SAWV DAWS SAWV RAWS INSULIN
■ Hloov los ntawm cov yeeb yam luv luv ua yeeb yam rau insulin analogue (piv txwv li Lizpro insulin) tso cai rau koj muab kev hloov pauv ntawm cov zaub mov noj rau cov neeg mob uas feem ntau yuam kom hloov nws vim kev ua haujlwm.
■ Cov nyhuv ntawm Lizpro insulin pib pib tom qab txhaj tshuaj, yog li ntawd cov tshuaj muaj peev xwm muab tau sai sai ua ntej lossis thaum noj mov.
■ Hauv kev sim tshuaj, Lizpro cov tshuaj insulin tsis qhia pom kev txhim kho kev tswj ntshav qab zib kom piv rau kev ua yeeb yaj kiab tiv thaiv kab mob ntshav qis.
Yet Tseem tsis tau pom zoo kom siv cov tshuaj insulin sib piv hauv cov menyuam yaus uas muaj 12 xyoos rov hauv thiab cov poj niam cev xeeb tub.
INSULIN QHIA RAU LUS TXWV
Fold Daim tawv nqaij yuav tsum tsim nyob ntawm qhov chaw txhaj tshuaj kom lub koob tau nkag hauv qab daim tawv nqaij thiab tsis nkag mus rau cov leeg nqaij. Daim tawv nqaij yuav tsum dav, rab koob yuav tsum nkag mus rau ntawm daim tawv nqaij ntawm kaum ntawm 45-60 °.
Areas Cov tawv nqaij tuab yuav tsum raug zam thaum xaiv qhov chaw txhaj tshuaj. Qhov chaw txhaj tshuaj tsis tuaj yeem hloov ua tsis tau zoo.
Tsis txhob txhaj tshuaj rau hauv qab tawv xwb pwg.
■ Cov insulins ua yeeb yaj kiab luv luv yuav tsum tau txhaj rau hauv cov nqaij mos subcutaneous ntawm lub plab phab ntsa 20-30 feeb ua ntej noj mov (ib qho tshuaj insulin tam sim ntawd ua ntej noj mov).
Ins Cov insulins ntev ntev tau muab tso rau hauv cov roj subcutaneous ntawm tus ncej puab lossis pob tw.
■ Ultra-luv-ua yeeb yam insulin txhaj tshuaj (humalog lossis Novorapid) tau muab tam sim ua ntej noj mov, thiab yog tias tsim nyog, thaum lossis tom qab noj mov tas.
Tus neeg mob yuav tsum tau piav qhia tias kub thiab tawm dag zog nce tus nqi ntawm kev nqus ntawm insulin, thiab txias txo nws.
Tib lub koob txhaj tshuaj thiab koob siv tau 4–6 zaug hauv 2-3 hnub.
Txhua tus menyuam yaus thiab tub ntxhais hluas uas muaj ntshav qab zib hom 1, poj niam cev xeeb tub muaj ntshav qab zib, cov neeg mob uas tsis pom kev zoo thiab txiav tawm qhov qis dua vim tias mob ntshav qab zib yuav tsum tau txhaj tshuaj insulin (koob txhaj tshuaj)!
COV NYIAJ UA NTEJ YUAV TSUM UA NOJ HAUV INSULIN
Illness Kev mob cuam tshuam lossis lwm yam kev ntxhov siab ntxiv qhov xav tau ntawm insulin.
Kev tawm dag zog lub cev ua kom cov ntshav qabzib muaj ntau ntxiv thiab tuaj yeem ua rau cov ntshav qabzib qis yog tias cov tshuaj insulin tsis raug txo lossis siv cov carbohydrates ntxiv.
■ Somogy Phenomenon: Insulin-induced hypoglycemia ua rau muaj kev tso tawm ntawm cov tshuaj tiv thaiv (adrenaline, cortisol, kev loj hlob hormone thiab glucagon), uas tau txiav txim siab ua rau hyperglycemia. Kev tsis quav ntsej ntawm qhov ua rau hyperglycemia thiab kev nce ntxiv ntawm cov tshuaj insulin ua rau cov ntshav qab zib ntau heev tshaj dua. Kev mob ntshav qab zib thaum pw tsaug zog yuav yog qhov tsis paub txog qhov ua rau muaj kev nce nrawm dua cov ntshav qabzib hauv siab, tej zaum qhov no, qhov kev txo qis ntawm cov tshuaj insulin tso cai koj los kho cov ntshav qog ntshav qab zib kom sawv ntxov.
■ Qhov tshwm sim ntawm "thaum sawv ntxov ntxov" (pom ob qho tib si hauv ntshav qab zib thiab ib txwm muaj) - nce ntawm cov ntshav qabzib thaj tsam thaum 5 txog 7 teev sawv ntxov, tshwm sim los ntawm kev kub siab ntawm kev loj hlob hormone nyob rau lub sijhawm thaum ntxov uas tsis muaj qog ntshav qab zib yav dhau los.
TSIS TXAUS SIAB RAU HAUV INSULIN THERAPY
Yp Kev mob ntshav siab ntshav qis.
Kev sib xyaw ua ke hauv zos thiab thoob ntiaj teb (tsis tshua muaj neeg paub nrog kev qhia txog tib neeg cov kua dej).
■ Cov qog tsim cov tawv nqaij thiab cov nplawm adipose tuaj yeem tshwm sim ntawm qhov chaw txhaj tshuaj insulin, tej zaum vim lub cev lipogenic ua haujlwm ntawm cov tshuaj insulin rau cov rog rog. Cov qauv tshuaj tuaj yeem ua rau me me tuaj yeem txo thaum qhov kev txhaj tshuaj nres ntawm cov chaw ntawm lipohypertrophy.