Cov tshuaj Metformin-Canon rau kev kho mob ntshav qab zib

Kev pham thiab kev nce rog hauv cov rog rog yog tsis txwv. Qhov no tsis yog ib qho txhaum tas mus ntawm tus neeg thiab nws tus cwj pwm, vim hais tias noj qee cov tshuaj provokes hnyav nce. Nws yog tsis yooj yim sua kom tiv thaiv lub txim ntawm kev kho mob yam tsis muaj tshuaj, uas ua rau lub sijhawm teem ntawm cov tshuaj Metformin Canon rau kev kho mob ntshav qab zib. Nov yog cov tshuaj ntsiav ntawm cov tshuaj hypoglycemic.

Ib yam khoom raws li metformin yog tsim, yog li ntawm kev muag koj tuaj yeem nrhiav cov npe lag luam txawv rau cov tshuaj no: Glucofage, Metformin Richter (Teva) lossis Siofor. Lub hom phiaj tseem ceeb yog kev kho mob ntshav qab zib, tab sis tam sim no nws tau siv los tswj kev hnyav dhau thiab rog dhau ntawm ntau hom.

Kev piav qhia thiab muaj pes tsawg leeg

Metformin Canon belongs rau lub koob thib 3 tiam ntawm biguanides. Nws yog siv rau hauv kev kho mob ntshav qab zib los ntawm kev kho kom cov lipid tshuav nyiaj thiab tswj qhov hnyav ntawm ib tug neeg.

Qhov peculiarity ntawm kev noj tshuaj, uas zoo cais nws los ntawm cov qauv tshuaj tiv thaiv, yog qhov tsis muaj ib qho kev ua ntxiv ntawm kev mob siab ntxiv. Metformin normalizes ntshav qab zib.

Cov muaj pes tsawg leeg ntawm cov tshuaj muaj xws li cov neeg tsis muaj npe:

Talc,
Primogel
Macrogol
Titanium thiab talc dioxide,
Povidone
Thaj av dawb.

Cov tshuaj tsuas yog muag hauv daim ntawv oval lossis round ntsiav tshuaj nrog lub thawb me ntsis, uas tau muab zais los ntawm lub plhaub dawb. Cov kev xaiv ntau ntau. Yog li, 500 mg ntsiav tshuaj tuaj yeem muas tau hauv thaj av 160 rubles rau 60 units, thiab kev lag luam npe Metformin Canon nrog cov tshuaj uas yog 2 npaug siab tshaj qhov qub dhau los - rau 138 rubles (30 pcs.). Thiab qhov thib peb ntau yam nthuav tawm hauv cov nyiaj ntawm 30 ntsiav tshuaj rau 90 rubles, yog tias cov koob tshuaj ntawm cov tshuaj nquag yog 850 mg.

Ntxiv dag zog rau cov txheej txheem ntawm cov piam thaj tau los ntawm cov leeg nqaij,
Kev ua haujlwm ntawm cov anaerobic metabolism hauv cov piam thaj hauv cov hnyuv,
Qhov kev xav ntawm cov roj (cholesterol) tag nrho txo,
Fatty acid oxidation hauv lub siab,
Lipid muaj pes tsawg leeg cov ntshav pab txoj kev,
Kev nqus thiab siv cov piam thaj los ntawm cov rog rog,
Txo cov ntshav qab zib
Qhov rhuav tshem ntawm glycogen nyob rau hauv daim siab.

Nco ntsoov nyeem: Flying nqos - tshuaj ntsuab tshuaj yej rau qhov poob phaus

Cov piam thaj hauv cov neeg mob txo qis, uas ua rau cov inhibition ntawm txheej txheem nqus los ntawm nws cov hnyuv phab ntsa. Raws li qhov tshwm sim, nws tau siv los ntawm lwm cov ntaub so ntswg thiab hloov mus rau hauv lub zog tsim nyog rau lub cev, thiab tsis muaj cov nyiaj khaws cia rog.

Cov tshuaj muaj ib qho tseem ceeb thiab tseem ceeb ua haujlwm - nws ua rau kom poob phaus, thiab qhov no yog qhov qhia tau zoo rau kev tswj glycemia kom raug rau cov neeg mob ntshav qab zib hom 2.

Kev taw qhia thiab contraindications

Kev siv tshuaj hypoglycemic nyob rau hauv cov tshuaj yog siv los ua tshuaj rau cov ntshav qab zib kom tsawg. Nyob rau hauv tib si, cov tshuaj nquag muaj ntau qhov tshwm sim zoo rau lwm cov kabmob thiab cov kab ke. Tab sis nyob rau lub sijhawm thaum lwm tus neeg sawv cev ntawm cov tshuaj no rau cov neeg mob ntshav qab zib tsis tswj hwm qhov theem ntawm cov piam thaj concentration tsis tswj, Metformin Canon tsis tso cai rau qhov tsis txaus siab poob qis dua qhov cim tsim nyog.

Lwm qhov zoo ntawm kev noj tshuaj:

Tsis qab los noj mov
Ua rau rhiab heev ntawm cov kab mob insulin,
Qhov kev txiav ua piam thaj hauv ib lub sijhawm thaum ib tus neeg tseem tsis tau noj vim yog qhov qis dua glycogen hauv lub siab,
Kev kho cov ntshav roj,
Ua rau qeeb ntawm kev tsim cov glycogen los ntawm cov protein thiab rog,
Hauv cov hnyuv, qhov nqus ntawm carbohydrates yog qhov txo.

Thaum noj tshuaj, muaj qhov raug zoo hauv kev txo cov roj hauv lub plab hauv plab, uas nyob ntawm qhov rhiab ntawm cov txais mus rau insulin. Muaj cov kev tshawb fawb nyob rau hauv uas cov kws tshawb fawb thiab cov kws qhia zaub mov noj haus hauv tebchaws Askiv tsim kom muaj kev vam khom lub neej ntev txog kev siv cov tshuaj no.

Ntau cov neeg rog xaiv tshuaj noj rau qhov hnyav dua vim qhov txo qis hauv kev nqhis khoom noj. Tab sis cov tshuaj Metformin Canon muaj ib qho tsis sib xws - nws cuam tshuam tus neeg mob txoj kev ua haujlwm. Siv cov kev kawm, nws yog qhov nyuaj rau tus neeg mus los ntawm tib daim ntawv teev cov kev tawm dag zog, yog li cov kws kho mob pom zoo thaum kho mob kom txo me ntsis qhov ntev thiab kev siv ntawm cov chav kawm.

Cov tshuaj Metformin Canon tau tsim tawm rau cov laj thawj hauv qab no: mob ntshav qab zib hauv cov neeg mob 10-xyoo thiab kev kuaj mob tib yam rau cov neeg laus. Cov chav kawm ntawm kev kho yog nqa ob qho tib si hauv kev sib txuam nrog lwm cov tshuaj hypoglycemic npaj, thiab raws li kev siv tshuaj kho mob nkaus xwb.

Nco ntsoov nyeem: Cov lus Fabkis Zoo Vichy qab zib rau cov cim ncab

Cov txheej txheem rau tshuaj yog qhov zoo heev:

Cev xeeb tub
Kev tsis txaus ntseeg ntawm lub siab, lub ntsws, lub raum,
Kev pub niam mis rau cov neeg mob
Pathological kev ntawm daim siab thiab biliary ib ntsuj av,
Mob ntshav qab zib Hom 1 thiab hom 2.

Cov kab mob thiab tawg, nrog rau ib qho kab mob ntev ntev, dhau los ua ib txoj kev cuam tshuam rau kev noj cov tshuaj no. Kev haus dej cawv thiab nquag ua raws li cov khoom noj kom nruj thiab tsawg cov roj ntsha ua rau lub ntsej muag ua rau muaj kev tshem tawm hauv chav kho mob.

Koj tsis tuaj yeem siv cov tshuaj rau cov neeg mob uas muaj kev puas tsuaj los ntawm kev ua pa ntawm daim ntawv tsis xwm yeem. Tom qab ib qho myocardial infarction, ib tug neeg raug txwv tsis pub haus cov tshuaj Metformin Canon thaum lub sijhawm rov ua kom zoo, nrog rau thaum rov kho dua tom qab kev phais lossis raug mob hnyav.

Tsuas tshuaj thiab tswj hwm

Txhua yam kev ntsuas no yuav qhia meej los ntawm tus kws kho mob uas tau mus kawm tom qab ua tib zoo tshawb xyuas thiab coj mus rau hauv tus lej tus yam ntxwv ntawm tus neeg mob txoj kev noj qab haus huv. Nws yog nruj me ntsis txwv tsis pub nws tus kheej noj tshuaj thiab sau tshuaj los yog kho cov zaus thiab ntau npaum li cas. Cov ntsiav tshuaj tsuas noj tom qab los yog thaum noj mov, tsis yog kev zom lossis tom, tab sis nqos. Nws yog qhov tsim nyog los haus nrog kua hauv qhov ntim ntawm 250 ml.

Thawj koob tshuaj yog 1000 mg, tab sis koj yuav tsum tsis txhob noj nws rau 1 zaug. Tus neeg mob yuav tsum faib cov ntsiav tshuaj ua ob peb zaug tshuaj. Cov kws kho mob piav qhia cov phiaj xwm no nrog qhov ua tau rau qhov mob hnyav ntawm tib neeg lub cev mus rau qhov kev ua ntawm cov tshuaj nquag - metformin. Thaum pib ntawm chav kawm ntawm txoj kev kho, cov neeg mob tuaj yeem soj ntsuam kev phiv, yog li, txhawm rau kom zam dhau lub xeev tsis kaj siab, kev noj kom tsawg txhua hnub yuav tsum muab faib ua ob peb qho me me.

Yog tias muaj pathologies ntawm lub plab zom mov hauv daim ntawv ntawm ntuav, raws plab, lossis mob hauv plab, koj yuav tsum tsis txhob tso tseg txoj kev kawm ntxiv. Cov kws kho mob tshwj xeeb thiab cov chaw tsim tshuaj txog kev noj tshuaj kom paub meej tias yuav txo qis cov tsos mob tom qab 2 lub lis piam nkag.

Hauv ob peb hnub tom qab no, thaum thawj cov tshuaj tiv thaiv rau cov tshuaj ua kom tsawg, tus kws kho mob yuav nce ntxiv rau 2000 mg ib hnub. Nws yog ib qho tseem ceeb kom nco ntsoov tias ntau tshaj 3 ntsiav tshuaj ntawm 1000 mg toj ib hnub yuav tsum tsis txhob nojCov. Cov tub ntxhais hluas hluas txij li 10 xyoo muaj cai haus Metformin-Canon noj nrog 500 mg ib hnub twg. Qhov zoo ntawm kev noj cov ntsiav tshuaj hmo ntuj yuav tsum tau fwm. Tom qab 2 lub lis piam, qhov ntim tau nce ntxiv 3 zaug, thiab qhov kev txwv ntau tshaj yog 2 ntsiav tshuaj ntawm 1000 mg lossis 4 ntsiav tshuaj ntawm 500 mg rau ib hnub.

Nco ntsoov nyeem: Noj Doppelherz tshuaj rau qhov poob phaus thiab rov qab los ntawm cov kev ua tsis tau zoo ntawm cov metabolism hauv lub cev

Cov kws kho mob thiab cov chaw tsim khoom taw qhia cov lus qhia tshwj xeeb rau cov neeg laus. Lub sijhawm ntawm cov chav kawm ntawm kev kho mob thiab kev noj tshuaj tsuas yog txiav txim siab los ntawm tus kws kho mob mus koom tom qab kev tshuaj xyuas thiab kev sib sau ua ke. Tab sis cov neeg mob hnub nyoog 60 xyoo tom qab noj cov tshuaj yuav yws ntawm lub raum tsis ua hauj lwm.

Kev phiv tshuaj thiab kev haus ntau dhau

Cov nyhuv ntawm Metformin Canon tsis yog qhov zoo tshaj plaws, tab sis koj tsuas yog yuav tsum muaj sia nyob nrog cov tsos mob no. Ntawm cov feem ntau kuaj pom muaj cov tsos mob li nram no:

Kev Hypovitaminosis B12,
Xeev siab thiab ntuav
Raws plab thiab tsam plab, roj,
Mob hauv plab
Ua kom tiav tsis qab los noj mov,
Kev Ntshav Qab Zib,
Megaloblastic anemia,
Ua xua rau tawv nqaij ua pob.

Hauv cov txheej txheem pathological los ntawm kev ua haujlwm tsis zoo ntawm lub plab, tus neeg mob yuav tsum tsis txhob ua dab tsi, vim tias cov tsos mob hla nws tus kheej tom qab 2 lub lis piam. Lwm zaus, koj yuav tsum tsis txhob noj cov ntsiav tshuaj thiab sab laj nrog koj tus kws kho mob.

Nyob rau hauv rooj plaub ntawm kev noj tshuaj ntau tshaj nrog cov ntsiav tshuaj tshuaj, tus neeg mob tau kuaj pom tias muaj kev loj hlob ntawm cov kab mob lactic acidosis. Tus mob no yog pom los ntawm cov tsos mob hauv qab no:

Tsawg kub
Ua kom sib haum tsis zoo
Tsis nco qab
Coma
Lub suab ntawm qhov hnyuv plab hloov pauv,
Kev mob siab rau hauv cheeb tsam epigastric,
Nqaij pob txha
Txog siav.

Nyob rau ntawm qhov muaj cov teeb meem hloov pauv loj uas yuav tsum tau hu tawm sai li sai tau ntawm pab pawg kho mob thiab tsev kho mob, kev siv cov tshuaj Metformin Canon yuav tsum tau tshem tawm. Txhawm rau tshem tawm cov khoom seem ntawm cov tshuaj tiv thaiv nquag hauv tsev kho mob, chaw kho mob hauv tsev kho mob.

Cov tshuaj tso tawm kom zoo nyob hauv qib tom qab thaj, thaum cuam tshuam lub cev rog. Tib qho uas ua rau cov neeg mob tsis meej pem yog qhov kev tsis zoo siab uas yuav tsum tau ua kom mob rau 10 lossis ntau hnub.

Dosage Cov Ntawv thiab Sib Sau ntawm Metformin Canon

Cov chaw tsim tshuaj lag luam nyob hauv Canonfarm ntau lawm tsim cov tshuaj nyob rau hauv daim ntawv puag ncig lossis oval convex ntsiav tshuaj hauv lub plhaub dawb. Ua raws li cov ntsiab lus ntawm metformin hydrochloride, ib hom tshuaj uas muaj tshuaj ntau npaum li 1000, 850, 500 mg tuaj yeem yuav hauv lub tsev muag tshuaj network.

Ntawm Metformin Canon, tus nqi yuav yog nyob ntawm txoj cai kev lag luam ntawm lub tsev muag tshuaj thiab cov koob tshuaj:

30 pcs 850 mg txhua. - 88-90 rubles.,
30 pcs 1000 mg txhua - 108-138 rubles.,
60 pcs. 500 mg txhua - 146-160 rubles.,
60 pcs. 850 mg txhua - 167-192 rubles.,
60 pcs. 1000 mg txhua - 248-272 rubles.

Ntxiv nrog rau cov nquag tivthaiv, cov tshuaj sib xyaw ua ke tseem muaj cov tshuaj ntxiv rau hauv cov qauv ntawm cov hmoov txhuv nplej siab, primogel, povidone, sodium stearyl fumarate, talc. Lub plhaub yog ua los ntawm dawb opadra II, macrogol, polyvinyl cawv, titanium dioxide thiab talc.

Lub txee lub neej ntawm cov ntsiav tshuaj yog 2 xyoos, cov tshuaj tsis xav tau cov kev mob tshwj xeeb rau kev cia khoom.

Kws Tshuaj

Metformin Canon yog qhov tshuaj noj suab thaj qhov ncauj, yog tus sawv cev ntawm chav kawm biguanide nkaus xwb. Nrog rau ib qho dhau ntawm cov piam thaj hauv cov ntshav, nws txo nws cov qib, inhibiting glucogenesis nyob rau hauv daim siab, thaiv nws qhov kev nqus los ntawm cov hnyuv phab ntsa, ua kom nws txoj kev siv nws los ntawm cov nqaij mos, qhov twg nws hloov mus rau lub zog, ntau dua li cov rog, vim qhov nce ntawm lub hom phiaj cell receptors rau insulin.

Txo cov tshuaj insulin kom tsawg dua rau cov nqaij sib kis, cov rog txheej yog qhov nyuaj dua rau kev zom zaub mov.

Metformin stimulates glycogen synthase thiab cell glycogenesis. Tsis zoo li npaj ntawm sulfanyl urea pab pawg, insulin ntau lawm tsis txhawb kev biagunids. Qhov no tsis tsim lub nra ntxiv rau cov txiav thiab lub hlwb b, tsis tsim kev puas tsuaj rau cov neeg mob ntshav qab zib hauv cov neeg noj qab haus huv uas siv cov metformin rau qhov kev poob phaus, kev tiv thaiv ntawm oncology thiab cov hlab plawv, lossis ua kom ntev lub neej hauv kev laus (tom qab 40 xyoo).

Ib qho mob tseem ceeb rau kev tswj hwm tag nrho ntawm glycemia hauv ntshav qab zib hom 2 yog qhov ib txwm ua rau lub cev hnyav. Tsis zoo li feem ntau cov tshuaj hypoglycemic, Metformin Canon yog qhov nruab nrab hauv kev sib piv rau qhov hnyav, thiab nrog tas li siv nws txawm ua rau txo qis me ntsis.

Cov Tshuaj Pharmacokinetics

Qhov nqus ntawm metformin nyob rau hauv cov phab ntsa ntawm lub plab yog nyob ntawm nws lub cev: yog tias koj noj cov tshuaj ua ntej noj mov, qhov nqus tau yog 48-52%, thaum koj siv cov tshuaj thaum tib lub sijhawm ua zaub mov, txoj kev ua haujlwm poob qis thiab qhov ua haujlwm poob qis.

Kev saib xyuas qhov siab tshaj plaws ntawm biagunide (2 μg / l) yog pom tom qab 2-3 teev. Cov tshuaj sib kis tau sai heev los ntawm cov ntaub so ntswg, nrog lub cev txoj kev cia siab txog 60%. Cov tshuaj metabolite tsis tuaj rau hauv cov ntshav, tab sis nws nkag mus rau hauv cov ntshav liab. Feem ntau ntawm cov tshuaj accumulates nyob rau hauv ob lub raum, mob siab, salivary qog. Thaum siv cov ntsiav tshuaj hnyav 850 mg, qhov xa tawm yuav yog 296-1012 litres.

Metformin metabolites hauv lub cev tsis pom, ob lub raum tshem tawm nws hauv qhov tsis hloov pauv. Hauv cov neeg muaj lub cev tsis sib xws, metformin tshem tawm yog nyob hauv thaj tsam ntawm 400 ml / min. Qhov kev tshem tawm ib nrab-lub neej yog 6.2 teev. Nrog lub raum pathologies, qhov ntsuas no nce, thiab nrog nws txoj kev pheej hmoo ntawm metformin, ua rau cov kab mob lactic acidosis.

Cov lus qhia rau kev teem caij Metformin Canon

Metformin Canon tau sau tseg rau cov neeg mob ntshav qab zib nrog hom 2 yog tias hloov kho kev ua neej (noj cov zaub mov kom tsawg, ua kom ib ce muaj zog, thiab tswj lub xeev lub siab) tsis muab glycemic tswj tiav.

Rau cov neeg mob nyhav dhau heev, metformin yog qhov kev xaiv zoo tshaj plaws. Cov tshuaj yog zoo ua ke nrog hypoglycemic tshuaj ntawm lwm pab pawg pharmacological, nyob rau hauv uas lub mechanism ntawm kev ua yog txawv los ntawm biguanides. Tej zaum yuav muaj kev kho mob dav dav nrog insulin.

Cov tshuaj kuj tseem tau hais txog kev kho mob ntshav qab zib hom 2 hauv cov menyuam hnub nyoog ntau dua 10 xyoo. Nws yog siv los ua thawj-kab tshuaj ib zaug lossis hauv kev sib xyaw nrog insulin.

Cov neeg tawm dag zog siv cov tshuaj no ua rau cov leeg qhuav, sim nrog kev poob phaus thiab cov ntxhais, tab sis kev siv no tsuas yog lav yog tias qhov teebmeem ntawm qhov hnyav tshaj yog txuam nrog kev tiv thaiv insulin thiab kev cuam tshuam ntawm metabolic.

LEEJ TWG pom zoo cov tshuaj metformin rau cov neeg mob noj qab haus huv tom qab muaj hnub nyoog 40 xyoo ntawm 200 mg / m / hnub. kom kav ntev lub neej (tiv thaiv ntawm atherosclerosis, kev mob plawv ntshav, oncology).

Neeg Mob Ntshav Qab Zib

Cov tshuaj no yog siv rau kev kho mob monotherapy lossis hauv txoj kev kho mob nyuaj nrog rau lwm cov tshuaj tiv thaiv kab mob. Qhov pib txhaj ntawm Metformin Canon, raws li cov lus qhia rau kev siv, yog 1000-1500 mg / hnub. Yog tias koj faib cov kev cai niaj hnub los ntawm 2-3 zaug, koj tuaj yeem txo qhov yuav raug rau hauv daim ntawv ntawm kev ua rau tsis zoo. Tom qab 2 lub lis piam, yog tias lub cev tau yoog, tab sis glucometer tsis yaum kom muaj zog, maj mam them ib feem kaum ntawm qhov ntau npaum li cas tau.

Thaum hloov lwm cov tshuaj analogues, ib qho yuav tsum tau coj los ntawm kev noj ntau npaum li cas ntawm cov tshuaj yav dhau los, nrog rau lub sijhawm lawv tshem tawm (daim ntawv ntev yuav tsum muaj qee lub sijhawm ncua).

Yog tias Metformin Canon tau raug tshaj tawm rau cov neeg mob ntshav qab zib ua ke nrog kev siv tshuaj insulin, qhov pib ntawm cov ntsiav tshuaj tsis pub tshaj ib chav nyob rau ib hnub ntawm kev noj tshuaj ntawm 1000 mg, 2-3 zaug / hnub. ntawm qhov ntau npaum ntawm 500-850 mg. Hauv qhov no, tus nqi insulin yog teev raws li cov yam ntxwv ntawm cov ntawv qhia zaub mov thiab kev qhia ntawm cov glucometer.

Tshuaj xyuas rau cov neeg mob

Mob ntshav qab zib Hom 2 nyob rau cov menyuam yaus tsis tshua muaj tshwm sim rau niaj hnub no, tshwj xeeb yog hauv cov tebchaws vam meej. Refined khoom noj khoom haus, lub cev tsis muaj zog, lub siab ntxhov siab tom qab tsim cov xwm txheej rau kev kis loj ntawm cov kabmob hauv menyuam yaus. Metformin Canon yog tsim rau cov menyuam muaj hnub nyoog tshaj 10 xyoo los ua ib cov tshuaj thawj zaug lossis hauv kev sib xyaw nrog cov tshuaj insulin.

Cov koob tshuaj pib, kev qhia pom zoo kom xaiv qhov tsawg kawg nkaus - 500 mg / hnub. Ib lub ntsiav tshuaj muab rau tus me nyuam thaum yav tsaus ntuj, thaum noj hmo. Hauv ob lub lis piam, koj tuaj yeem soj ntsuam qhov tshwm sim ntawm kev kho thiab kho qhov tshuaj, maj mam nqa nws mus rau qhov kev saib xyuas txij nkawm (1000-1500 mg / hnub) lossis ntau kawg (200 mg / hnub). Qhov kev siv tshuaj txhua hnub tau muab faib ua 2-3 koob tshuaj.

Cov Neeg Mob Cov Laus

Xyoo dhau los, hauv cov neeg mob ntshav qab zib nrog kev paub dhau los (thiab tsis yog xwb), lub peev xwm ntawm lub raum tsawg dua, yog li Metformin Canon tau raug tshuaj rau kev saib xyuas kev ua haujlwm ntawm lawv txoj haujlwm txhua txhua rau lub hlis. Lub sijhawm kawm yog teem los ntawm tus kws kho mob, nws raug nquahu kom tswj lub sijhawm ntawm kev noj tshuaj rau hom mob ntshav qab zib no thiab tsis cuam tshuam kev kho mob yam tsis tau txais kev pom zoo los ntawm tus kws kho mob endocrinologist.

Cov lus pom zoo ntxiv

Kev kho mob nrog Metformin Canon yuav tsum tau soj ntsuam txhua hnub ntawm cov glucometer thiab sau cov txiaj ntsig hauv qhov chaw muag mis nyuj ntawm tus mob ntshav qab zib. Ntxiv nrog rau kev yoo mov qab zib, nws yog ib qho tsim nyog yuav tau kuaj xyuas thiab xaib tom qab, 2 teev tom qab noj mov. Yog tias cov txiaj ntsig tau dhau dhau ntawm ib qho dhau los ntawm ntau tshaj 3 mmol / l, koj yuav tsum kho cov zaub mov noj.

Thaum muab tshuaj rau, cov ntshav qab zib tau ceeb toom txog qhov yuav tshwm sim tsis tuaj yeem ua tiav: yog tias xeev siab thiab ntuav, mob hauv plab plab, mob leeg thiab tsis muaj zog tuaj, koj yuav tsum tso tseg kev siv tshuaj thiab qhia qhov teeb meem rau tus kws kho mob.

Cov teeb meem me me tsis haum plab (tso quav thiab noj zaub mov) yuav ploj mus yam tsis muaj kev pab kho mob, tab sis qee cov cim yuav yog thawj qhov hu ntawm kev tsim cov mob lactic acidosis.

Metformin, zoo ib yam li lwm yam tshuaj rau qhov ncauj hypoglycemic, raug tso tseg ob hnub ua ntej kev ua haujlwm, kev kuaj mob xoo hluav taws xob (suav nrog kev tiv thaiv tsis zoo, iv urography), uas siv iodine-based radiopaque cim. Rau lub sijhawm no, cov ntshav qab zib tau pauv mus rau insulin. Cov txheej txheem kev kho mob yav dhau los xa rov qab 2 hnub tom qab ua tiav ntawm cov txheej txheem, yog tias nws tus mob tsis tas yuav siv lwm yam kev ntsuas.

Metformin raug tshem tawm los ntawm lub raum, yog li ntawd, ua ntej pib ua haujlwm thiab thaum lub sijhawm noj tshuaj, creatinine tshem tawm yuav tsum kuaj xyuas: nrog lub raum zoo - 1 zaug hauv ib xyoos, nrog txo KK thiab kev laus - 2-4 zaug / xyoo.

Cov tsos mob ntawm kev kis tus kab mob ntawm lub ntsws, ntsws thiab urogenital kheej kuj yuav tsum yog lub laj thawj ntawm kev mus ntsib tus kws endocrinologist.

Tawm tsam keeb kwm yav dhau los ntawm kev siv tshuaj metformin, dej cawv tshwj xeeb tshaj yog. Kev txwv tsis pub los ntawm lub luag haujlwm ntawm daim siab, ua cov glycogen endogenous, hem txoj kev loj hlob ntawm hypoglycemic thiab disulfiram-zoo li cov neeg mob.

Kev nqus tau cov vitamin B 12 tsis txaus ntseeg tau los ntawm kev thaiv nws txoj kev nqus. Qhov teeb meem tshwm sim nrog lub sijhawm ncua ntev ntawm cov tshuaj thiab yog thim rov qab. Yog tias pom cov tsos mob ntawm hypovitaminosis B12 raug pom, metformin yuav tsum hloov nrog analogues.

Cawv rau lub peev xwm tswj hwm cov khoom siv nyuaj

Metformin Canon tsis cuam tshuam rau kev tswj hwm kev thauj khoom lossis cov txheej txheem nyuaj yog tias nws tau siv hauv kev kho mob monotherapy. Nrog cov kev kho mob nyuaj nrog sulfonylureas thiab cov tshuaj insulin, ib qho kev tiv thaiv hypoglycemic yog qhov ua tau, uas cuam tshuam loj dua psychomotor kev xav thiab kev saib xyuas.

Yam tsis tau xav txog

Metformin yog cov tshuaj uas muaj cov pov thawj muaj txiaj ntsig ntawm kev nyab xeeb thiab ua tau zoo, tus txheej txheem kub hauv kev kho mob ntshav qab zib, tab sis cov tshuaj pom tau tias cov neeg mob ntshav qab zib sib txawv. Feem ntau qhov tsis xav tau qhov tsis txaus ntseeg yog dyspeptic; thaum lub sijhawm hloov kho, qee leej tswj kom zam lawv. Yog tias koj noj ntsiav tshuaj nrog zaub mov, maj mam ntxiv qhov ntau dua, koj tuaj yeem txo cov tsos mob ntawm tus mob plab.

Lwm qhov huab yog lactic acidosis, uas tshwm sim nrog kev txuam nrog metformin hauv lub cev txuam nrog raum tsis ua haujlwm. Cov xwm txheej zoo li no yog muaj tsawg heev, kwv yees ua ntej thiab xav kom thim cov tshuaj Nws yog qhov yooj yim rau kev soj ntsuam qhov degree ntawm qhov tshwm sim ntawm kev phiv los ntawm ntau yam plab hnyuv siab raum thiab kev siv tshuab hauv lub rooj.

Organs thiab tshuab

Hom ntawm phiv

CNShloov hauv saj (saj ntawm hlau)feem ntau Kev kho mob txoj hnyuvpoob ntawm qab los noj mov, dyspeptic cuam tshuamheev heev Hepatobiliary systemdaim siab ua tsis tiav, kab mob siabpheej xav Kev ua xuaerythema, tawv nqaij ua pob khaus thiab khaus, urticariatsis tshua muaj Kev paub kev zom zaub movlactic acidosistsis tshua muaj neeg pom Lwm yam kev xaivHypovitaminosis B12, tsis tuaj yeem nqus tau ntawm folic acid, megaloblastic anemiatsis tshua muaj neeg pom

Tag nrho cov kev mob tshwm sim yog qhov thim rov qab thiab ploj tom qab tshem tawm ntawm Metformin Canon. Cov kev tshawb fawb soj ntsuam pom tias thaum muaj hnub nyoog 10-16 xyoo cov xwm txheej thiab cov zaus tshwm sim los ntawm cov kev mob tshwm sim zoo ib yam li cov neeg laus.

Contraindicated kev sib txuas ua ke

Cov tshuaj tiv thaiv hluav taws xob sib xyaw ua ke raws li iodine, siv rau hauv kev tshawb nrhiav hluav taws xob, tuaj yeem ua rau cov kab mob lactic acidosis thaum noj tshuaj metformin. Yog li, 2 hnub ua ntej cov txheej txheem thiab 2 hnub tom qab kuaj xyuas, cov ntsiav tshuaj tau hloov nrog cov tshuaj insulin.

Cov Kev Siv Muaj Txiaj Ntsig

Thaum siv danazol nrog metformin, kev mob hypoglycemic yog ua tau. Yog tias tsim nyog, xws li kev sib koom ua ke yog qhov tsim nyog kom qhia meej cov koob tshuaj metformin.

Cov koob tshuaj tseem ceeb ntawm chlorpromazine thaiv qhov kev tso tawm ntawm cov tshuaj insulin endogenous, nce qib suab thaj. Antipsychotics kuj tseem xav kom tau ib feem kaum ntawm ib koob tshuaj metformin thaum kho cov kab mob sib luag thiab tom qab nws txiav tawm.

Glucocorticosteroids txo qis cov ntshav qabzib, thaum nce nws qib hauv ntshav, ketosis muaj peev xwm tshwm sim hauv qhov xwm txheej huabCov. Nrog rau kev teem sij hawm ntawm cov kev ua dag zog li no, tus nqi ntawm metformin yog txo.

NSAIDs thiab ntxig cov diuretics nrog metformin ua rau lub raum ua teeb meem. Tus mob no yog qhov txaus ntshai rau kev loj hlob ntawm cov kab mob lactic acidosis.

Nifedipine ua kom zoo dua rau qhov nqus thiab qhov siab tshaj plaws ntawm metformin, qhov tseeb no yuav tsum raug coj los txiav txim siab thaum nqus ib qho kev kho mob.

Txhim kho lub ntsej muag hypoglycemic ntawm cov tshuaj thiab kev sib txuas nrog acarbose, insulin, sulfonylurea tshuaj.

Cov tshuaj siv los tswj cov ntshav siab tuaj yeem txhim kho cov nyhuv hypoglycemic thiab xav tau titration ntawm ib koob tshuaj metformin.

Cov Yuav Tsum Muaj

Ntxiv nrog rau kev ua kom tsis haum rau cov khoom xyaw ntawm cov mis, cov tshuaj tsis yog kws kho:

Nrog rau cov mob ntshav qab zib tsis xeev, precoma, ketoacidosis,
Rau cov ntshav qab zib uas muaj CK qis dua 60 ml / min.,
Muaj kev cuam tshuam los ntawm cov mob tsis zoo (lub cev qhuav dej, kub taub hau, mob hnyav),
Nrog hypoxia tshwm sim los ntawm kev poob siab, sepsis, pathologies ntawm ob lub raum ntawm mob keeb kwm, mob ntsws, ntsws,
Cov neeg mob uas muaj mob los yog mob ntev ua rau cov nqaij mos hypoxia,
Rau lub sijhawm ntawm kev phais mob, nyob rau hauv kev kho mob ntawm kev raug mob hnyav thiab kub hnyiab,
Tus cawv mus sij hawm ntev, cov neeg uas haus cawv heev,
Nrog daim siab ua hauj lwm tsis zoo,
Hauv lub xeev lactic acidosis,
Cov menyuam yaus hnub nyoog qis dua 10 xyoo, cev xeeb tub thiab lactating niam,
Ib ntus: kev txwv nyob rau lub sijhawm ntawm kev ua haujlwm thiab kev tshawb nrhiav hluav taws xob.

Hom ntawm overdose

Hauv cov kev tshawb fawb soj ntsuam hauv cov neeg ua haujlwm pab dawb uas tau noj tshuaj kaum zaus ntawm metformin (85 g), cov ntshav qog ntshav qab zib tsis txhim kho, lawv pom cov cim ntawm cov kab mob lactic acidosis.

Koj tuaj yeem paub tus mob los ntawm kev tsis haum siab, kev hloov pauv ntawm lub suab ntawm lub plab, qhov kub qes qis dua qhov qub, mob nqaij ntshiv thiab mob epigastric, ua pa luv, ua tsis taus kev sib koom tes thiab nco qab, tsaus muag thiab tsis nco qab. Tus mob yuav tsum tau maj tawm yeeb tshuaj thiab mus pw hauv tsev kho mob. Cov lactate thiab metformin cov khoom seem hauv tsev kho mob yog kho los ntawm hemodialysis.

Kev Ntsuas Cov Tshuaj Ntshav Qab Zib

Txog Metformin Canon, kev tshuaj xyuas feem ntau yog qhov zoo. Ntau tus sau tseg tias muaj cov tshuaj ntawm cov nqi peev nyiaj. Ib nrab ntawm cov neeg mob qhia tias tswj cov piam thaj kom ruaj khov, ua kom yuag, qab los tswj.

Ntawm qhov kev ntsuas tsis zoo, kev tsis txaus siab ntawm cov kev mob tshwm sim hauv daim ntawv ntawm txoj hnyuv chim siab uas muaj feem ntau dhau sijhawm. Pom tseeb, hauv cov xwm txheej zoo li no, nws tsim nyog sab laj nrog koj tus kws kho mob, vim tias txawm tias metformin-based analogues muaj ntau yam kev pabcuam uas tuaj yeem ua rau ua xua thiab lwm yam tshuaj tiv thaiv. Nws yog qhov ua tau los hloov cov generic nrog thawj Glucophage.

Analogues ntawm cov tshuaj

Rau Metformin Canon, ntau hom tshuaj yeeb yaj kiab tuaj yeem yog analogues. Pharmacological sib npaug nrog kev kho mob zoo ib yam thiab cov khoom siv yooj yim ntawm metformin yog:

Glucophage - ib hom tshuaj Fabkis qub tsim nyog txog 130 rubles.,
Metfogamma - Cov ntsiav tshuaj German ntawm tus nqi nce txog 330 rubles.,
Formmetin yog txoj kev pabcuam hauv tsev, lawv muag rau 250 rubles.,
Sofamet yog lus Bulgarian, tuaj yeem yuav rau 109 rubles.

Raws li kev ua ATX kev faib tawm, cov npe tuaj yeem raug ntxiv los ntawm Siofor, Bagomet, Avandamet, Metformin Teva thiab lwm yam duab. Cov chaw tsim khoom ntawm Metformin Canon kuj muaj qhov sib txawv nrog cov nyhuv ntev. Cov tshuaj maj mam tso tawm muaj nyob hauv qhov ntau npaum li 500, 750 thiab 1000 mg. Cov tsiaj ntawv ua ntej "ntev" thiab muaj lwm yam analogues

Kev lag luam kws tshuaj niaj hnub muaj ntau yam tshuaj tiv thaiv kab mob, tab sis tawm ntawm 10 chav kawm ntawm cov tshuaj tsim los tswj hom 2 ntshav qab zib, metformin ib leeg tseem tsis muaj kev tiv thaiv. Qhov no tsuas yog tus nqi pheej yig, kawm tau zoo uas yog tus mob ntshav qab zib xav tau thaum twg los tau.

Cov lus qhia tseeb txog metformin tuaj yeem nrhiav pom hauv video.